Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F6 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12004135
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
E2F6 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12004135
MFHAS1 NEK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
HMGN2 NEK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NEK11 FKBP5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDC37 FKBP5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
BLM MYC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23750012 30415952 29467282
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
VAPA FKBP8 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32877691 26496610
BLM CHEK1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CHEK1 E2F6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23954429
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
MYC HMGN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333 11085504
E2F6 NEK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12909625
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CDC25A CHEK1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CHEK1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21050475 20719863 25015292 25906194 15364958
CHEK1 CDC25A â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17568790 17582221 18677104 19793801 20126263
MYC CDC25A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8994810 10205150 11154267 9371770 14519204 15677471 17671423
CHEK1 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 75.0 1.0 Omnipath 12676583 22040655 29435105 12759351 14681206 18677104 20860841 15798197 19793801 22655267 12963847 16682204 14752276 16647857 15736430 29725502 17116885 17582221 20126263 16697662 18167338 19075565 9278511 18480045 17384638 21148633 21252624 27493659 12110582 17030123 23335075 20068082 11298456 27908669 27213455 25936524 15459660 28150240 20798862 22263797 27038604 17296725 14559997 12399544 17102137 17568790 16488126
MYC CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
NEK11 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 22263797 14603323 20090422 19734889 20348946 15021892 22099186 15798217 22655267 14752276 21252624
CHEK1 NEK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20090422 19734889 22655267
NEK2 NEK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15161910 17145710