Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
XRCC2 RAD51D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10749867 5212428
PCNA CHAF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
PCNA FEN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
PCNA FANCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20937699
H2AX SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
H2AX UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H2AX SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H2AX ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19146767 11673449
ATM H2AX â—¼   COLOCALIZATION 2.0 0.8 intact 16858402 5218840
H2AX FANCD2 â—¼   COLOCALIZATION 2.0 0.8 intact 7906544 19609304
H2AX RAD51 â—¼   COLOCALIZATION 2.0 0.8 intact 8149296 21317870
SUMO1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16478998
KAT5 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ATR BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TP53 BARD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14636569 15782130
TP53 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCRS1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UIMC1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MRE11 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
MRE11 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
MRE11 FANCD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7906544 19609304
MRE11 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
MRE11 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
MRE11 ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
MRE11 RBBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21052091 8081463
RAD50 MRE11 â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
PARP1 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18025084
H3C2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
H3C2 PARP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
PARP1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
KAT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10096020
APBB1 H2AFX â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16818236 19234442
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO1 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
ATM RBBP8 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TIMELESS ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19996108
ATM HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
ATM PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12147700
NBN ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
RPA3 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BLM ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
DNA2 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
RPA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
CHEK1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0706013104 17686975
BRCA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TOP3A ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR RMI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR BRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR RBBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR RMI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TP53 ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9925639 10435622
ATR BRCA1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 23422745
TIMELESS ATR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17644383
ATR HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
ATR PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12147700
TOP3A ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BLM ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
DNA2 ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
NBN ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
WRN ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP RBBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP FANCD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20670894 23723247
ATRIP RMI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP BRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP RMI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP EXO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP FANCI â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20670894 23723247
TP53 ATRIP â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9925639 10435622
CHEK1 ATRIP â—¼   COLOCALIZATION 2.0 0.8 intact 20639859 8010047
ATRIP TOPBP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086392 20871591
ATRX POT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
BLM PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16864798 0601828103
BLM RPS27 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16864798 0601828103
XRCC3 BLM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
RAD51C BLM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
ESR1 BLM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17268063
BLM RPS27 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16864798 0601828103
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
FANCD2 BRCA1 â—¼   COLOCALIZATION 2.0 0.8 intact 11239454 5213674
PARP1 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 7596430 376037
CHEK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218401 16511572
RPA2 CHEK1 â—¼   COLOCALIZATION 2.0 0.8 intact 20639859 8010047
CHEK1 FANCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19861535
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
RPA2 DNA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18593712 23604072
RPA1 DNA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18593712 23604072
RPA3 DNA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18593712 23604072
ESR1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 19039095
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
TOP3A FANCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8140640 21240188
FANCB FANCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16720839 17396147
TP53 FANCC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9063748
TP53 FANCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
HSP90AA1 FANCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18266962
MYC FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20638938 19366810
JUN FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21460851 20638938
FEN1 MUS81 â—¼   COLOCALIZATION 2.0 0.8 intact 22551069 8372920
RPA1 FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592449
HERC2 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
MYC HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20388374 19021144
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
JUN TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910340 9448005
UBE2I KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KLF12 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KAT5 SYN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 MLH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15781865
MYC MSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12808131 11983916
TP53 MSH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12209975
RAD51C MUS81 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
XRCC3 MUS81 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
NBN SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
NBN SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
NBN UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RAD50 NBN â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
PARP1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PARP1 TIMELESS â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SUMO1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
SUMO3 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
TP53 PAXIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
PLK1 TP53BP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 1000287 20126263
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
TBPL1 POT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23342266 21423278
SUMO1 RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
UBE2I RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO2 RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO2 RAD51 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19956565 1000252
RAD51C TOP3A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
RAD51C RMI1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
RAD51C RMI2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
WRN RAD52 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216387 12750383
WRN RAD52 â—¼   COLOCALIZATION 2.0 0.8 intact 5216387 12750383
RPA2 RIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC3 RMI1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
RMI1 RMI2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
XRCC3 RMI2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
SUMO2 RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
UBE2I RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RNF8 RNF168 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20385750
RNF8 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RNF8 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RPA1 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 20705237
RPA1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 20705237
RPA1 SUMO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 20705237
TIPIN RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17644383
TOP2A SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18394993 25114211
SUMO1 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20016603 25114211
TP53 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11420669 21187340
SUMO1 UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17698038
SUMO3 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11451954 17938407
SUMO2 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1004248107 20534433
SUMO2 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
TBPL1 TERF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23342266 15380063
TOP3A TERF2 â—¼   COLOCALIZATION 2.0 0.8 intact 6743819 18418389
TERF2 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21824286 8202878
TIPIN TIMELESS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17116885 0609251103
TOP3A TINF2 â—¼   COLOCALIZATION 2.0 0.8 intact 6743819 18418389
TOPBP1 TOP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17006541 5219150
XRCC3 TOP3A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
TOPBP1 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086392 20871591
UBE2I TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
BLM RPA2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
XRCC4 TERF2 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
ATM RBBP8 â—¼   PHOSPHORYLATION ✅ - 0.8 0.8 Signor 10910365
BLM ERCC6L â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
RAD50 ATM â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 18854157
ATM RAD50 â—¼   PHOSPHORYLATION 0.8 0.8 Signor 17570479
ATM WRN â—¼   PHOSPHORYLATION 0.8 0.8 Signor 10608806
RAD50 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 10426999
ATM EXO1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 20019063
MRE11 H2AX â—¼   COLOCALIZATION ✅ 0.81 0.81 mint 22157895 8303386
SUMO2 RIF1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 29234018 19471022 32786267 21252943 21693764
RAD51 SUMO1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
BLM TIMELESS â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
CHEK1 RAD51 â—¼   PHOSPHORYLATION ✅ + 0.81 0.81 Signor 15665856
H2AX RAD50 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15201865 31501894 16377563 10959836 18583988 19234442
XRCC6 BARD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 15782130
JUN P53 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 31182485
MYC RFA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
FACD2 TOP3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25659033 31180492
FACD2 FANCG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18212739 31180492
RFA2 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16169070 20711169
RFA3 TOP3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24126761 24332808
RFA3 RMI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24126761 24332808
TP53B XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 29656893
MRE11 NBN â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
ZN512 BLM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BLM AIPL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27173435
APBB1 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ATRX XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30585729 23329831
MECP2 BLM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BLM PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24239288 34079125
BRCA1 ETAA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29656893 27723720
BRCA1 TINF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34112789 29656893
ESR1 CAND1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
MYC ECT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
ESR1 MSH6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
ESR1 RAP1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
PARP1 JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 24636898
JUN XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 30585729
MECP2 TOP3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC MIB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
XRCC6 MSH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 21075794
MX1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25447205 11716541
MYC RFC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC SF3B2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RAD50 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC PSMD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC TOP2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC TPP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
UIMC1 PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 25252691
RAD52 SUMO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 8812453 10666456
RFC1 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30585729 26344197
SUMO2 WRN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19471022 16524884
ATM CHEK1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 20068082
BLM RPA3 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
FANCL FANCI â—¼   UBIQUITINATION ✅ + 0.82 0.82 Signor 18985065
ATR MRE11A â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
FBXO18 PCNA â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
FACD2 H2AX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17304220 19609304 31180492
XRCC6 P53 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11751391 15782130 32807901
RFA1 XRCC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30585729 24981860 24332808
FANCA RFA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22705371 12973351 12724401
MYC FACD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17314511 24658369
ATR RFA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17035231 24332808 15929725
RFA2 XRCC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26344197 10064605 24981860 24332808
ATM RFA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10713094 9725899
RFA2 PARP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24332808
RFA3 WRN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24126761 30279242 27173435 24332808
MYC TP53B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29656893 29467282 20195357
ATRX NBN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27171262 24651726 23329831
ATRX RAD50 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24651726 23329831
PLK1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31730000 25483079 29656893 24067368
BRCA1 TERF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19797051 29656893 34112789
BRCA1 TERF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19797051 25184681 29656893 34112789
RPA2 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 11953755
HES1 FANCA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18550849 19321451
FANCB FANCG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16720839 27986371 17396147
HES1 FANCG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18550849 19321451
JUN TOP2A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649 8387155
BRCA1 RBBP8 â—¼   UBIQUITINATION ✅ + 0.83 0.83 Signor 16818604
RBBP8 BRCA1 â—¼   RELOCALIZATION ✅ + 0.83 0.83 Signor 24832651
H2AFX RNF8 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
ATM NBN â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10802669
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HERC2 RPA1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BRCA1 FANCD2 â—¼   UBIQUITINATION ✅ + 0.83 0.83 Signor 12485996
FEN1 WRN â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
KAT5 MYC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
RAD52 TP53BP1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
PARP1 UBE2I â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
RFC2 RFC4 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
BLM RAD50 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
DNA2 FEN1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
RFA1 PCNA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11254741 20227374 15831485 21504906 24958773 12171929
PCNA TOP1MT â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
PCNA XRCC6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11239001 24695737 12171929
BLM H2AX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15364958 29523790
BARD1 H2AX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12485996 11927591
BARD1 FANCJ â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17664283 25252691 27399284 16391231 18628483 20451671
FACD2 FAN1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29051491 20603073 25135477 24794430 20603016 20603015
BLM FACD2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15257300 25135477 31180492
RFA2 WRN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24126761 30279242 20802463 24332808
TP53B RAD50 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20010693 29656893
TP53B RIF1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29234018 29203878 29656893
ATRX MRE11 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27171262 24651726 23329831
KAT5 APBB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32296183 15044485 15331662 14699153 11441186 33849647 16713569 16223726 25342469 17368826
MSH2 BLM â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15064730 10783165
MSH6 BLM â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15064730 10783165
SUMO2 BLM â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19471022 16524884 16620772 21693764
PARP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 34079125 26831064 25252691
ESR1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15961505 31527615
HES1 FANCE â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26277624 18550849 19321451
XRCC3 FANCG â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20450923 16621732 18212739
HNF4A SUMO2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 22505616
NBN MLH1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10783165 17121922
RAD51 RAD51C â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
TOP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
FANCF FANCL â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
BARD1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
PCNA FACD2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19704162 25893307 31180492
H2AX XRCC6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15613478 33961781 23145133 20224553 28514442 18406329
EGLN3 P53 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26972000 30067985
P53 HERC2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31665549 22653443 28977907 27259994 24722987
FANCJ RFA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17596542 20159562
FANCJ FACD2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26336824 25070891 31180492
RAD50 BLM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25084169 10783165 29523790
FANCA BLM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22705371 12973351 23509288 22343915 12724401
BLM MYC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30415952 29467282 23750012
BLM TOP3A â—¼   COLOCALIZATION ✅ 0.85 0.85 mint 20711169 8048867
SUMO2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21147198 20016594 20016603 22689573 21693764
BRCA1 TOP2A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25184681 15965487
RNF8 NBN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26869104 18001825 23115235
SUMO2 PARP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19471022 25027693 32786267 19779455 21252943 21693764
TOP3A RMI2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 20826342 20711169 26186194 20826341 28514442
SUMO1 WRN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16524884 15355988 19596686
BRCA1 WRN â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
BRCA1 FANCA â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
MLH1 PCNA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28439008 32814904 15225546
H2AX NBN â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 6805208 18583988
NBN H2AX â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 22157895 8303386
H2AX NBN â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 22565321 8391733
DVL2 PLK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32707033 25659891 31340145
FBXW7 P53 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 28514442 31940492 31346036
TEP1 P53 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10597287 16713569
TP53B NBN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20010693 29656893 20081839
NBN BLM â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10783165 29523790
BRCA1 RFC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25184681 10783165 16713569
FANCF FANCC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16720839 15262960 23303816 24469828 18550849 11063725 27986371 17082180
MYB FBXW7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18765672 21092141
SUMO1 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19779455 15561718 23871147 15576338 19596686
PARP1 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20085707 34079125
SUMO1 SUMO3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 25027693 17938407 21098080 15576338
SUMO2 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19471022 25027693 19394292 18381449 32786267 21252943 20797634 21693764
WRN XRCC6 â—¼   PHOSPHORYLATION ✅ 0.86 0.86 mint 10783163 5212534
BRCA1 MSH2 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
BLM MSH6 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
MRE11A RPA1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
TP53 WRN â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
ATR TP53BP1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
TERF2 H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21044950 22157895 21824286
WRN H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20802463 15733840
ATM H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18344987 26095369 21704408 22451927 11893489 20081839 16858402 9488723 22184063 11571274 21676867 32518374 27918549
H2AX RAD51 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21317870 28190324 30560944 31009828 10959836 28796254 29499138
BARD1 MSH6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16391231 11498787
BARD1 FACD2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12887909 31180492
P53 KAT5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17189186 23677994 18280244 18485870 33849647 17704809 15310756 16601686
RMI1 RFA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24126761 15775963 24332808
FACD2 RAD50 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19609304 31180492
FACD2 RAD51 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27694619 12239151 25893307 30818369
BLM RFA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24332808 12724401 24126761 28506294 30279242 15775963
RMI1 RFA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24126761 15775963 24332808
BLM RFA3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24332808 12724401 24126761 30279242 15775963
ATRIP RPA1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BRCA1 MRE11A â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ESR1 UIMC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31527615 17311814
FANCB FANCL â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16720839 27986371 17396147
FANCD2 FANCE â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FANCF FANCG â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RNF8 HERC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22508508 20023648 22814251 26503038 25305019
MYC RFC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 17314511 29467282
MYC TOP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 17314511 29467282 20195357
SUMO1 RAD51 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24046452 10666456 19956565 9891849 8812453
RAD52 WRN â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
APBB1 KAT5 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
FEN1 MSH2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MRE11A TERF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
RAD50 TERF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
RMI2 TOP3A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ATR TP53 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BLM CHEK1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BLM RMI2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PCNA UBE2I â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BLM TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
POT1 TERF1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 TOPBP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
COPS5 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ERCC6L PLK1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CHAF1A PCNA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ATM BRCA1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRIP1 TOPBP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CHEK1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ATR BRCA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BLM FEN1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BRCA1 MLH1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
FAN1 MLH1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
FAN1 FANCD2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
RNF168 TP53BP1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SUMO1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PCNA TP53BP1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
FANCM RAD52 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TERF2 XRCC6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BRCA1 RPA1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
BRIP1 MLH1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
FEN1 MRE11A â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
H2AX MRE11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12419185 15201865 31501894 16377563 22157895 18583988 19234442
P53 TOP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8639538 11805286 16713569 10468612 18697815 32807901
TP53B RFA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15856006 29656893
RFA1 MSH2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 24332808
TIPIN RFA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24126761 17296725 20679368
BRCA1 RFA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23901102 19369211 29656893 21240188 19766185
MRE11 FACD2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19609304 12447395 31180492
TP53B RFA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15856006 29656893
FANCJ BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24895130 21240188
ATM MRE11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10783165 15758953 10608806
MRE11 BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10783165 28506294 29523790
ATM BLM â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BRCA1 BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25084169 29656893 26831064 10783165
BLM RIF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23509288 20711169
HNF4A RAD50 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 35140242 17353931
MYC PLK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29467282 27773673 30415952 17314511 33494392
WRN PARP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14596914 14734561
CASP3 PARP1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
RPA2 TIPIN â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ATR ATRIP â—¼   PHOSPHORYLATION ✅ + 0.88 0.88 Signor 15451423
FANCC FANCG â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MRE11A RBBP8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
NBN RBBP8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
H2AFX MRE11A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
RAD51C XRCC2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
FBXW7 JUN â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ATM H2AFX â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RPA1 XRCC6 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
XRCC4 CORO7 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
H2AFX PARP1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
TP53B H2AX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21566653 12697768 21317870 28242625 18001825 17024177 15364958 20075863 21623170 12607005 18001824 26734725 31009828 12447390 29662616 29499138
H2AX PARP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28796254 28242625 16377563 27728808 18406329 28514442 20000738 20085707 16522924
BARD1 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26022179 14636569 15782130 21742769
SUMO1 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16732283 23150668 15017387 10961991 18583933 21316347 15327968 23825024 17369817 23543742 15931224 16713569 19684601 15144954 11867732 23604351 12917636 17060459 15576338 15242646 19246003 23772552 16189514 20534433 22214662 20972456 10562557 10788439 16122737 20861261 32807901
MYC P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28205554 28628118
P53 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17545634 26556313 10766163 16713569 21761334
P53 TOP2A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10666337 32807901 16713569
TOP3A RFA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24126761 24332808 12724401
ATRIP RFA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23723247 25916848 26854234 12791985 17526493 31757956 24332808 22258451 16407120 15743907 18936170 21859891
ATR RFA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18162465 10608806 24332808
FACD2 NBN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19609304 12447395 31180492
ATM FACD2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14499622 12086603
RFA2 TOP3A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24126761 30279242 24332808
RAD52 RFA3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24126761 19338310 8702565
BLM TP53B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15364958 17984114 29656893
SUMO1 TP53B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 20016603 29656893
TP53B BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22884692 17525332 21552324 29656893 12364621 31009828 18001824 26831064
PLK1 TP53B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25607646 20126263 25659891 32707033 26291670
TERF2 MRE11 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18212065 22939629 10888888 19287395
MRE11 XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30585729 10508516 26344197
BRCA1 ATRIP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17616665 29656893 24073851
ATRX RAD51 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10426999 29656893 10783165 11504724 25659039 25939603 25184681 19244116 18171670 12124328
BRCA1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
MLH1 BRIP1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5220047 17581638
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
MLH1 FAN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 27880917 29051491 32296183 20603073 26496610 25659891 17148452 20603015
FANCF FANCE â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20064461 15262960 16127171 26277624 27986371 17082180 12093742
MYC FANCI â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 29467282 17353931
MYC MLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29467282 12584560
MRE11A XRCC6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
XRCC6 MSH6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30585729 22863883 21075794
MYC MSH6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17314511 29467282 17353931
RFC4 MYC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 29467282 17353931
MYC XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282
TERF2 NBN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22939629 10888888 19287395
WRN TERF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12181313 18212065
XRCC6 TERF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10984620 26496610 21044950
PLK1 ERCC6L â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 17218258
FANCM RMI2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RAD51 TP53 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FANCL FANCD2 â—¼   UBIQUITINATION ✅ + 0.89 0.89 Signor 17396147
H2AFX XRCC6 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
BLM RAD52 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
EXO1 MRE11A â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
POT1 TINF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
WRN PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12633936 12750383 16713569 10871373 20600238
NBN H2AX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16932743 12419185 11110662 15201865 18001825 31501894 20081839 23145133 16377563 18001824 22157895 18583988 22941933 21676867 15733840
H2AX BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18344987 12419185 26095369 20681793 19805520 18001825 31501894 26121674 10959836 12485996 18001824 19766185 11927591 34321665 29499138
RPA3 BARD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 BARD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 BARD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
BARD1 DNA2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 16697054 19772495 19847258
ESR1 BARD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17275994
HNF4A P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 11818510 16713569 28514442
ATM P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23890999 9765199 16858402 15713674 23525106 25086746 10713094 11875057 30252118 15790808 10864201 11551930 17157788 10744722 28654064 11709713 16713569 11459832 20010693 19965871 9843217 17409407 14744854 24469230 15064416 10673501 23907539 21383020 10608806 15159397 27559048 15632067
BLM P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15806145 11781842 12606585 22653443 15364958 12080066 24239288 16713569 32807901 11399766
ATR P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20798688 10435622 10673501 16293623 10747897 15775976 9765199 11883897 11551930 15159397 10608806 11709713 10951572 11459832 15082766
TP53B P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33606978 25837623 12110597 22653443 20307547 25651062 14985081 30252118 15364958 16713569 26022179 27546791 14978302 25579814 11877378 19433796 22084066 8016121 12351827 15611139 16169070 17805299
WRN P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11427532 15735006 12080066 16713569 11399766
P53 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14978302 9582019 14710355 21742769 18501503 9482880 14636569 9926942 16677609 26140185 19509300 15571721 16713569 16969499 31073355
P53 PLK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15024021 19833129 22653443 16753148
P53 RAD51 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16983346 15064730 8617246 11948396 14636569 16600179 12606585 26140185 16713569 11002423 9380510 12750285
P53 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12898523 14627987 9565608 32807901 16713569 9312059 23169665 15044383
P53 RFA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8361542 8663296 15735006 23267009 9121469 11751427 15489903 32807901
BLM RFA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11950880 10825162 15965237 25135477 12724401 24332808 12181313 24239288 24126761 26474068 30279242 15775963
WRN RFA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15965237 24332808 15735006 24126761 27723720 26474068 14499497 30279242 10373438
RFA3 RFA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 22939629 26496610 7760808 21504906 19338310 12527904 26344197 8663296 20811460 8972858 8663111 24126761 11927569 2159011 10336450 9461578 27723720 12509449 26474068
FANCI FACD2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21719678 25168188 18931676 19561358 32510829 24794430 25319828 28684355 25489943 24451376 30456385 24623813 23993743 27773793 31180492 17460694 28575658 25862789 33795880 20603015 22855611
FACD2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14499622 25652403 31180492 29656893 11239454 16713569 12887909
FANCE FACD2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17308347 12649160 23303816 24451376 16127171 15115758 19704162 26277624 16513431 12093742
RFA2 TIPIN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24126761 24910198 20679368
RFA3 RFA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10982866 33961781 24981860 22939629 7760808 19338310 26344197 8663296 8972858 11081631 11173472 8663111 24126761 8157639 11927569 10449415 17976647 28514442 10336450 16189514 9461578 12509449 15965237 26186194 10064605
ATM TP53B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12697768 29656893 20081839 22621922 12447390 11042216 20010693 18996087
FANCJ BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18285836 22032289 19369211 17664283 29656893 20173781 11301010 14576432 17525342 28911102 17525341 25252691 27399284 30257991 20159462 20681793 15242590 16713569 19452558 21240188 15208681 15125843 14578343 17525340 17581638 23157317 11877378 24573678 26831064 22792074 17596542 15133502 23530059 18628483 16391231 14576433 25184681 18717574 28398198
MLH1 FANCJ â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25502805 20978114 23585563 17581638 16391231 24966277 20173781 24573678 22968820 17148452 22792074
RPA2 MRE11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 MRE11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 MRE11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
BRCA1 MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10426999 11353843 17349954 23530059 24413181 16391231 29656893 11504724 25184681 10783165
NBN MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12750284 12419185 24413181 21884979 24981860 22939629 12679336 10426999 28369484 17526493 9705271 26455393 12607003 17612497 12447395 22464731 22078559 22231403 34348893 28363998 11062235 15758953 11238951 23530059 33558481 15734743 34038735 30179224 12861053 18458108 19270065 17500065 10783165 30440001 22941933 19244116
RBBP8 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17965729 21052091
PHF8 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20531378 20210320
TERF1 ATM â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15314656 18160036 11375976
RPA3 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
KAT5 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16141325
ATRIP ATR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17686975 14657349 15210935 17384638 20616048 17526493 18162465 21285353 26854234 19097996 18283122 15743907 15451423 14724280 15538388 28514442 23144622 15758953 19889979 18344416 20847938 11721054
CHEK1 ATR â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15190204 10859164 11390642
ATR UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18519686
TOPBP1 ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20068082 18769153
RMI1 BLM â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20360068 20064461 20826342 23509288 26496610 24239288 20711169 15775963
BLM TERF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12181313 19329795 15229185
BRIP1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21240188
RAD51 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11498787 31270457 19369211 14636569 24085845 29656893 28319063 25659039 34408138 31009828 9774970 16713569 25499220 19766185 17302439 9008167 28976962
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
FANCA BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12354784 29656893 16713569 21240188
JUN BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25609649 12080089 16713569
MLH1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16786532 29656893 21240188 17148452 25184681 10783165
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 MSH6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11498787 16260778 25184681 10783165
CASP3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12149654
BRCA1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 9774970 9008167
RPA2 BRIP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 BRIP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 BRIP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
CASP3 RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9235961 9351817
TIMELESS CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15798197 23418588
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
ESR1 PWP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
FANCE FANCC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12239156 12649160 15262960 14625294 11157805 16127171 24451376 27986371 23303816 18550849 26277624 24469828 16513431 12093742
TP53 FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23518350 19366810 12824889
TP53 FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31346036 12824889
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
RPA1 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
TP53 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18431400 15781865
MYC MSH2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29467282 30415952 28205554 17314511 28628118 12584560
TP53 MSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11350971 8630028
MYC RFC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NBN RPA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
NBN RPA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
TOP1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15247263 15848144 34079125
RPA1 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
TERF2 RAD50 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18212065 22939629 10888888 19287395 15100233
RPA3 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 RBBP8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 RBBP8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 RBBP8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 RMI2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 RMI2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 RMI2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
SUMO1 RNF4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24844634 23086935 29180619 32296183 15707587 24151981 24907272
RNF4 SUMO1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 SUMO2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
TP53 SUMO3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
TIPIN TIMELESS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12875843 17644383
TIMELESS TIPIN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12875843 17644383
TP53 WRN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9774636 11427532
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
H2AFX NBN â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
RPA2 RPA3 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ATR RPA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ATR WRN â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MSH2 PCNA â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CHAF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PROXIMITY ✅ 0.91 0.91 mint 25281560
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
BLM RMI1 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 20711169 8048867
FANCM MUS81 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
FANCD2 FANCL â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
APITD1 FANCE â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
APITD1 FANCL â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
APITD1 FANCC â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
APITD1 RMI2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
APITD1 FANCB â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
APITD1 RPA2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
APITD1 RPA1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
BLM C17ORF70 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
BLM STRA13 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
C17ORF70 RMI1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
C17ORF70 TOP3A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
C17ORF70 FANCE â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
C17ORF70 STRA13 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
C17ORF70 RMI2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
FANCA RMI2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
FANCC STRA13 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
FANCE STRA13 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
FANCF STRA13 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
RMI1 STRA13 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
RPA1 STRA13 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
RPA2 STRA13 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ATM NBN â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
MLH1 MSH6 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
TOP1 TOP2A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
MSH2 MSH6 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
H2AX KAT5 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 23777805 20224553 18406329
RPA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RPA3 RPA2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24126761
ATR CHEK1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 15775976
FANCM RPA2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
RAD51C XRCC3 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
RNF4 SUMO2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
RAD51D XRCC2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
FEN1 MSH6 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
BLM XRCC3 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
FBXW7 MYC â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
BLM MRE11A â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
FBXO18 RAD51 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
RAD51 UBE2I â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
SUMO1 JUN â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 11867732 15469925 10788439
BLM MUS81 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
H2AFX TP53BP1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
TIMELESS WRN â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NBN RAD50 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
MRE11A TP53BP1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
RAD52 RPA2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
BLM PAXIP1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
RAD51C RAD51D â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
TERF1 TINF2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
FANCM MSH6 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EXO1 TERF2 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
RPA1 WRN â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
TOP3A WRN â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
PCNA MSH2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 8858149 16189514 12171929 15225546
MSH6 MLH1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 30770470 12799449 10748159 10783165
SUMO1 TOP1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 24654937 11709553 12439742 15576338 12149243 19596686
BLM MLH1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
MSH2 BRIP1 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
PAXIP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
WRN XRCC6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
ATR BLM â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
RAD51 RPA1 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
RFA1 MRE11 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 30179224 18936170 24332808 19586055
RAD51 RFA2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 19338310 9826763 15929725
MSH2 MLH1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 12799449 30770470 10748159 25241761 31843968 10783165
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
MLH1 MSH2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RAD52 TERF2 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
PCNA TOP1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
BLM TP53BP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
DNA2 RPA1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
MRE11A NBN â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
RFC2 PCNA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 8093561 9228079 26496610 24958773 12171929
RFA1 RAD51 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19338310 9826763 12077133
FANCA FANCG â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 17396147 5219816
SUMO1 TOP2A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12832072 10862613 19596686 18381449
SUMO2 UIMC1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
SUMO3 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CHEK1 TP53BP1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
EXO1 MLH1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
RAD52 RFA1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28551686 9826763 8702565 24126761 12139939 12077133
RAD52 RFA2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11081631 8702565 15929725 24126761 12139939
ATM MRE11A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
RAD50 NBN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 19197236 22939629 12679336 10426999 26344197 17526493 9705271 12607003 17612497 12447395 22464731 34348893 11062235 15758953 12124328 11238951 26215093 23530059 15734743 16391231 24651726 30179224 17500065 30440001 22941933 10783165
RAD52 RAD51 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28551686 9826763 20190268 12750383 17118963 9837724 10666456 15766559 19338310 10212258 8550550 10448035
TINF2 TERF1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10581025 15383534 28514442 21044950 19487455 33961781 15316005 11701125 26496610 16880378 16169070 15133513 26186194 20811636 17589526 25416956 15181449 28216227
EXO1 MSH2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
INTS3 NABP2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
NBN TERF2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RPA1 TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MSH6 PCNA â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
FANCM RPA1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TERF2 TINF2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RMI1 RMI2 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
BRIP1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5220047 17581638
BLM RPA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BRCA1 BRIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BRCA1 RBBP8 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RAD52 RPA1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPA1 RPA3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RFA2 RFA1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 7876167 24981860 22939629 26496610 28575657 7760808 21504906 22863883 12527904 20679368 26344197 8663296 25499885 24443570 20811460 30279242 8972858 12754299 32296183 8663111 24126761 11927569 2159011 28514442 10336450 9461578 27723720 12509449 15965237 26186194 26474068 10064605
RAD50 MRE11 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12750284 24413181 24981860 19197236 22939629 31501894 30733337 10508516 26344197 8756642 28369484 9705271 26455393 12607003 16163361 11504724 34348893 28363998 11062235 26215093 27173435 23530059 33558481 15734743 16391231 24651726 17694070 34038735 17500065 19270065 30179224 10888888 10783165
MSH6 MSH2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 9428522 15064730 26344197 8942985 10748159 22939629 25241761 26496610 14657349 10856833 9774676 10783165 10029069 19377479
BLM RAD51 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RMI1 TOP3A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
TIMELESS TIPIN â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PCNA RPA1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
APITD1 C17ORF70 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
APITD1 FANCG â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
APITD1 BLM â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
APITD1 TOP3A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
APITD1 RMI1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
APITD1 FANCF â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
APITD1 FANCA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
C17ORF70 FANCM â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
C17ORF70 FANCA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
C17ORF70 FANCL â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
C17ORF70 FANCG â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
C17ORF70 FANCF â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
C17ORF70 FANCC â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
C17ORF70 FANCB â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCA FANCM â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCA FANCG â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCA FANCC â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCA RMI1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCA STRA13 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCB FANCM â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCC FANCM â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCE FANCM â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCF FANCM â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCG STRA13 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCG FANCM â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCL FANCM â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCL STRA13 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MRE11A RAD50 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TOPBP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FEN1 PCNA â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RFC1 RFC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPA1 RPA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RFC2 RFC4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
BARD1 BRCA1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
APITD1 STRA13 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
APITD1 FANCM â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
FANCM STRA13 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
FANCM RMI1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RAD52 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
XRCC3 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
XRCC3 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
FANCD2 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD52 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
FANCD2 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RPA2 PCNA â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA MLH1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20154325 22118461 11274057 23840062
PCNA MSH6 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 20713735 20154325 22118461 11274057 11441019 11005803 18326858 17984070 11809883 16188885 16143102
PCNA FANCD2 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA RAD51 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA FANCI â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA WRN â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 10858306 11283614 11585362 11756412 11948190 12202749 12637553 14624239 14726013 15385537 15703371 15871698 16216273 16442856 16449207 16697054 17055429 17116323 17426133 17599061 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19748837 19847258 20027199 20056333 20064462 20691907 20713526 20955519 21376743 21727086 2191300 21922195 22021614 22455312 22657828 22743550 22973052 23082994 23110144 23161013 23253856 23414611 23485469 24036544 24050180 24709898 9407949
PCNA H2AFX â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA FEN1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
PCNA EXO1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11438669 11756412 14624239 14676842 14726013 15474417 15703371 16697054 18048416 18087292 18584027 18756267 18809224 19490890 1974050 19772495 19847258 20019063 20478261 22021614 23414611
PCNA CHEK1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA ATRIP â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA ATR â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA BRCA1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
RPA2 PCNA â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA FEN1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
PCNA CHEK1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA ATRIP â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA ATR â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA FANCD2 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA RAD51 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA WRN â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 10858306 11283614 11585362 11756412 11948190 12202749 12637553 14624239 14726013 15385537 15703371 15871698 16216273 16442856 16449207 16697054 17055429 17116323 17426133 17599061 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19748837 19847258 20027199 20056333 20064462 20691907 20713526 20955519 21376743 21727086 2191300 21922195 22021614 22455312 22657828 22743550 22973052 23082994 23110144 23161013 23253856 23414611 23485469 24036544 24050180 24709898 9407949
PCNA H2AFX â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA FANCI â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA EXO1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 11438669 11756412 14624239 14676842 14726013 15474417 15703371 16697054 18048416 18087292 18584027 18756267 18809224 19490890 1974050 19772495 19847258 20019063 20478261 22021614 23414611
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA BRCA1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BLM PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 22973052 23253856 24089143 24095737
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
JUN PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22550165 19940138 1352831 15205327 23078099
PCNA FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 28514442 15576034 8668533 3113402 11601988 12853968 31467278 1477073 24958773 7673186 16216273 11313979 15616578 8876181 14657243 11430825 26496610 16189514 9305916 22606318 28073635 19153658 26751069 26186194 9178907 22592530 24728180 17115032 18692475 26030842 16326861 29997244 22556262 9545252 31515488
PCNA EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20970388 16189514 15225546
PCNA RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8999859 12400013 15225546 19285992 10353443 12192049 9649448 26496610 12045192 12171929 24958773 8861969 9092549
XRCC6 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H2AX UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
H2AX ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
H2AX PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H2AX RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
ATR H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 20461094 20976184 20471486 22224778 17303408 28797244 18677104 19622404 15798197 19793801 9488723 20860841 12919958 18158901 20165693 20936109 22002605 26114388 29114052 21283714 22819196 19282663 24893124 17116885 22531632 17582221 30013081 25438756 26019182 17384638 19647519 20205745 23166506 25852739 18471973 27442013 22247744 29584802 20542002 19875294 25249630 20368801 15459660 27332952 27715493 19772495 25247188 17296725 11877377 14643438 24813610 20613862 17102137 20847938 21148072 23443128 27431324 29163782 23754961 17690115 15975956 18663141 21787120 22545090 27077811 19781914 27164092
BRCA1 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18001824 18001825 17145710 12419185
ATM H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 197.0 1.0 Omnipath 27410735 28544233 16426903 28797244 9488723 23847653 30197789 21930799 18158901 21693595 18848500 22819196 15603757 16760673 17570479 24688021 24793032 27458206 16531125 22028490 30154456 19230794 23202908 25852739 19059218 26073471 22247744 28259974 29584802 25691887 19049966 20368801 26700820 29386061 28124509 20613862 27550454 20847938 27388041 27752097 23269287 24480460 22237206 20461094 20971043 26941327 18285803 21690091 15279774 23891287 25847270 24490130 25349305 26906421 20637859 26314960 15286739 27780918 20454618 30013081 28671946 25218945 23742011 26391293 23972723 23382699 26416514 27442013 20703100 24726884 26512707 27332952 29641431 25287622 26295265 14643438 29163809 25264544 19895790 26504743 26113859 27431324 28790385 18413980 21283714 21787120 20205745 19781914 25093845 27135971 23227178 22224778 20923785 20860841 24244154 23386996 30065307 16858402 11879731 28009280 23343929 20192759 22761798 26855420 24378750 20068231 20580718 14504478 24893124 29048667 25661368 26860083 26019182 20488183 28764946 22205726 23977391 18471973 19591958 28239143 20542002 17525332 20495376 18755145 23050241 17782711 11571274 19473884 28431265 25742493 18248856 17690115 20684759 26317467 21727091 24651472 25827888 27164092 28587922 20976184 30723510 20471486 23772364 29794999 11893489 19014481 20165693 26671524 16997395 20936109 26114388 23845989 15138496 22761813 23355489 27455285 28943310 21348461 19647519 23678292 23166506 28099474 29434792 25249630 25269479 27310012 15177039 22559321 26045162 20865059 22972376 21148072 26760771 21188122 22962268 22768044 26711340 20460517 27845910 28855246
RNF8 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19772495 7575488 18590585 17303408 18001824 18678890 18583988 18001825 18678709 12607003 9407949 17660363 18006705 15279786 15459660
RNF168 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19342239 22980979 31533041 18443409
H2AX TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 20075863 18001824 21317870 12447390 17024177 18001825 21566653 12607005 12697768 21623170
RMI2 BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
FANCD2 BARD1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD50 BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
WRN BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RAD51 BARD1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
TOP3A BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 BARD1 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
DNA2 BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BARD1 EXO1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BARD1 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BARD1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BARD1 XRCC3 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 BARD1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
FANCD2 BARD1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 BARD1 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BARD1 XRCC3 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
TP53BP1 BARD1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
BARD1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 99.0 1.0 Omnipath 16403807 16391231 28262780 15159397 25652403 26350354 26490435 14647430 11927591 25184681 16713569 11526114 35203293 9738006 12732733 24289923 11573085 18936166 23086937 24085845 12890688 15855157 24695549 19369211 9798686 11257228 11498787 12700228 11925436 10477523 19176389 23680151 25634209 23416467 34726323 29355525 18369654 14636569 11504724 12951069 19117993 20060929 17873885 14638690 18493658 11278247 15184379 22110403 11301010 11773071 12431996 10635334 20029420 9788437 17664283 21901007 25252691 12485996 10026184 12438698 17525341 16489000 8944023 15265711 12419249 20681793 9342365 27239795 20215511 25823446 19916563
PLK1 DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20823832
FEN1 MRE11 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
XRCC6 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MRE11 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
MRE11 WRN â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 DNA2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
MRE11 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
MRE11 TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 EXO1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
PLK1 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15845385 28512243
ATM MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19709933 26240375 17570479 31353207 10608806
RAD50 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19197236 16163361 10888888 8756642 17713585
MRE11 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 22464731 26455393 12861053 17500065 15734743 12419185 19270065 22078559 19244116 21884979 12679336 11238951 12607003 9705271 17713585 10783165 12447395 10426999 18458108 15758953
CHEK1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 18451105 20068082 23844048 12560483 18066052 20948546 21357687 18243098
SIRT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18337721 16439206 19408108
MLH1 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
DNA2 ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
XRCC6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
WRN ATM â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
BRCA1 ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
H2AFX ATM â—¼   PHYSICAL_INTERACTION 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
ATM RAD50 â—¼   PHYSICAL_INTERACTION 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
ATM RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
ATM RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
WRN ATM â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
H2AFX ATM â—¼   SHARES_COMPLEX 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM RAD50 â—¼   SHARES_COMPLEX 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
H2AFX ATM â—¼   ENZYMATIC_REACTION ✅ 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM TERF1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11331603 11877377 12607003 15140942 15459660 15964794 16163361 17303408 22266654 22634377 23847781
ATM RPA2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM BRCA1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM FANCD2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM EXO1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM PARP1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM CHEK1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
MSH2 ATM â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
MSH6 ATM â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
MLH1 ATM â—¼   UP_REGULATES ✅ + 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
H2AFX ATM â—¼   REGULATES ✅ 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM RAD50 â—¼   REGULATES ✅ 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
PAXIP1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15456759 19414588 17690115
ATM RIF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18077418 15342490
ATM FANCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17525332 19109555
ATM RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17525332 11359916
ATM RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 29875999 15964794 11877377 17303408 9725899 16163361 14872059 23847781 9139719 10713094 9295339 20860841 16731533 12607003 22977173 7171818 15459660
ATM TERF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 17717821 15314656 17570479 23732473 26586433 11375976 22266654
ATM NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 12433983 12861053 17485521 23146902 10839545 19413330 15302935 27602502 17429352 19523210 24360018 20068231 17507690 17570479 10608806 12598907 18669648 25088203 18003706 11252893 17431132 23097684 10766245 12814430 10802669 21664921 26512707 10839544 11927276 21130714 17525332 12447395 14707289 15733840 15279770 25119968 18644472 28822740
ATM NABP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25249620 26170237 28448822 21051358 18449195 23178594
ATM BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16199871 11146546 25766002 17984114 14643436 20719863 17363339 14729972 18054789 12034743 30496191 16880735 11375976
ATM FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17412408 17525332 28636932 32117957
ATM CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 69.0 1.0 Omnipath 29774099 20976184 26683224 25663895 12676583 17303408 14657349 29167438 27545311 10859164 19056039 15485915 28808226 12588868 16163361 15650047 12676962 17570479 14988723 14681223 26516160 10608806 26069190 29741650 12676925 23847781 17118344 11252893 20376879 15964794 15149599 18691976 19059218 20068082 15707391 12607003 25450480 17525332 11553781 19646247 15870257 15459660 20798862 19716789 11877377 12660173 11390642 15674326 16782033 28396830 28228262 12446774 15533933 15212693 29555944
ATM TOPBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11756551 18077418 19279141 17525332 17446169
ATM FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 16280053 17303408 15057286 12427531 15607958 25891850 16163361 21466974 20068231 14499622 17570479 12086603 19774700 23847781 14599770 15964794 22057367 28825622 12607003 17525332 15459660 16943440 15979372 11877377 27094386 15279770 28552166 12612651 19101576
ATM TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16223874 17525332 15314656
ATM FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17525332 26774286
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 26927092 17303408 15159397 24746700 12024016 10866324 30197789 12919958 11114888 26745677 26383678 34301763 12427729 11313470 16163361 28035057 20068231 25939603 26320175 17570479 19683496 22743550 10608806 23802008 23847781 21203981 15964794 12183412 12607003 17525332 19996295 15459660 11278964 19651622 21706030 11877377 20952512 10373534 19622773 10550055 27170701 15212693 23704879
ATM EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 15964794 11877377 17303408 18756267 16163361 15867354 23847781 23675572 25956864 26240375 11438669 24705021 12607003 18048416 17525332 20019063 15459660
ATM RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 23468639 23675572 17570479 24837676 10910365 16249056 11689934 10608806 17525332 22743550
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATM RAD50 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17570479 17081983 15302935
RPA2 ATR â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR TOPBP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
ATR TIPIN â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
ATR FANCD2 â—¼   PHYSICAL_INTERACTION 58.0 1.0 ACSN 11438669 11850621 11877377 12086603 12607003 14988723 15136767 15175241 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18087292 18469862 18511906 18543256 18584027 18677104 18716619 18756267 18809224 18931676 18995830 19004803 19282663 19342888 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 20723763 21376743 22743550 22751496 23444773 24050180 9488723 9858600
ATR ATRIP â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR RPA3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RAD50 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11850621 11877377 12086603 12607003 14988723 15136767 15175241 15459660 15798197 16713580 16805667 17102137 17116885 17296725 17384638 17582221 18087292 18469862 18584027 18677104 18809224 18931676 18995830 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 22751496 23444773 24050180
ATR FANCM â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11877377 12086603 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15175241 15189446 15459660 15798197 16337602 16697054 16713580 16805667 17035102 17102137 17116885 17296725 17384638 17582221 18157158 18448394 18469862 18472307 18550849 18677104 18931676 18995830 19217833 19225445 19258535 19282663 19342888 19622404 19686080 19772495 19793801 19847258 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
ATR CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR TIPIN â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
ATR RAD50 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11850621 11877377 12086603 12607003 14988723 15136767 15175241 15459660 15798197 16713580 16805667 17102137 17116885 17296725 17384638 17582221 18087292 18469862 18584027 18677104 18809224 18931676 18995830 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 22751496 23444773 24050180
ATR FANCD2 â—¼   SHARES_COMPLEX 58.0 1.0 ACSN 11438669 11850621 11877377 12086603 12607003 14988723 15136767 15175241 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18087292 18469862 18511906 18543256 18584027 18677104 18716619 18756267 18809224 18931676 18995830 19004803 19282663 19342888 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 20723763 21376743 22743550 22751496 23444773 24050180 9488723 9858600
ATR TOPBP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
ATR ATRIP â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR FANCM â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11877377 12086603 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15175241 15189446 15459660 15798197 16337602 16697054 16713580 16805667 17035102 17102137 17116885 17296725 17384638 17582221 18157158 18448394 18469862 18472307 18550849 18677104 18931676 18995830 19217833 19225445 19258535 19282663 19342888 19622404 19686080 19772495 19793801 19847258 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
MSH6 ATR â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
MSH2 ATR â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
MLH1 ATR â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
ATR CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR PARP1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR BRCA1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR FANCG â—¼   ENZYMATIC_REACTION ✅ 70.0 1.0 ACSN 11438669 11877377 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 15459660 15485915 15798197 15867354 16332722 16337602 16540648 16697054 16713580 16731533 16885023 17035102 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18157158 18448394 18469862 18472307 18511906 18543256 18550849 18677104 18716619 18756267 18931676 18995830 19004803 19217833 19225445 19258535 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 19847258 20019063 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957 9488723 9858600
ATR H2AFX â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR FANCD2 â—¼   ENZYMATIC_REACTION ✅ 58.0 1.0 ACSN 11438669 11850621 11877377 12086603 12607003 14988723 15136767 15175241 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18087292 18469862 18511906 18543256 18584027 18677104 18716619 18756267 18809224 18931676 18995830 19004803 19282663 19342888 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 20723763 21376743 22743550 22751496 23444773 24050180 9488723 9858600
ATR FANCA â—¼   ENZYMATIC_REACTION ✅ 70.0 1.0 ACSN 11438669 11877377 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 15459660 15485915 15798197 15867354 16332722 16337602 16540648 16697054 16713580 16731533 16885023 17035102 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18157158 18448394 18469862 18472307 18511906 18543256 18550849 18677104 18716619 18756267 18931676 18995830 19004803 19217833 19225445 19258535 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 19847258 20019063 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957 9488723 9858600
ATR EXO1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR FANCI â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
RPA2 ATR â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
HES1 ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
ATR FANCM â—¼   UP_REGULATES ✅ + 52.0 1.0 ACSN 11877377 12086603 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15175241 15189446 15459660 15798197 16337602 16697054 16713580 16805667 17035102 17102137 17116885 17296725 17384638 17582221 18157158 18448394 18469862 18472307 18550849 18677104 18931676 18995830 19217833 19225445 19258535 19282663 19342888 19622404 19686080 19772495 19793801 19847258 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
ATR FANCA â—¼   UP_REGULATES ✅ + 70.0 1.0 ACSN 11438669 11877377 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 15459660 15485915 15798197 15867354 16332722 16337602 16540648 16697054 16713580 16731533 16885023 17035102 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18157158 18448394 18469862 18472307 18511906 18543256 18550849 18677104 18716619 18756267 18931676 18995830 19004803 19217833 19225445 19258535 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 19847258 20019063 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957 9488723 9858600
ATR FANCG â—¼   UP_REGULATES ✅ + 70.0 1.0 ACSN 11438669 11877377 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 15459660 15485915 15798197 15867354 16332722 16337602 16540648 16697054 16713580 16731533 16885023 17035102 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18157158 18448394 18469862 18472307 18511906 18543256 18550849 18677104 18716619 18756267 18931676 18995830 19004803 19217833 19225445 19258535 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 19847258 20019063 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957 9488723 9858600
RPA2 ATR â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TOPBP1 ATR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16530042 18769153 16285702 18066086
MSH2 ATR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19847258 16612326 14657349 16713580 20478261 15703371 18543256 12947387 19473888 19595721 19596235 18157157 16697054 19596236 18406444 21285353
ATR XRCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23438602 26354865
ATR CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 29774099 26683224 26658951 28180282 27545311 29605721 16461339 26165835 24971543 28937603 28573382 27713304 27643582 18723495 26082189 25205668 29088070 22971344 20536192 22353182 28051860 19276361 14681223 14988723 26069190 23892398 12676925 11252893 26643553 16520097 23383325 20396397 16431910 19059218 21440578 22357623 24753408 28572758 11090622 25795119 29309644 15870257 34398682 19716789 23508805 25965828 24947324 23380594 19071136 23118481 28396830 15533933 15190204 19737971 24023735 27283761 28025997 23696651 16360315 28915668 15707569 19062161 14657349 19489726 21937510 25448276 26721387 27558808 25104095 19056039 23468519 17081992 20679434 20062519 28808226 27679857 12588868 22203733 29928473 25459351 28558031 12766152 26748709 28986587 18265945 18669648 27775084 18691976 12781359 23583268 29221122 26633513 34509474 22564734 31928997 33863777 27685627 27167194 29118324 30796221 24366029 11390642 21907702 24632611 27068998 24349411 31591366 17686975 15665856 19781914 21736880 12676583 27690219 23386996 21482692 24113549 21730979 15775976 15272308 17851138 33811702 27271602 30510197 28273450 29209046 23849791 18794134 25024738 12676962 26438152 20932473 15279789 20376879 16414131 15149599 24387336 18790091 24327542 17525332 19646247 23997120 20798862 29022904 15674326 24500207 16137618 12446774 16885021 20639859 19101576 20976184 25663895 24244353 27603133 10859164 23333305 24621867 22863316 24072747 15650047 22084686 10859163 21851590 23613359 15629715 29741650 17118344 22706734 25565400 25301724 17327276 23006513 29242514 24906880 15707391 27908669 18353973 27708213 18243098 18603484 12660173 18955550 26039276 19473886 28255082 25898113 29163782 16629900 25937999 30100999 24140082 24970150 22084169
ATR FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17296725 11877377 19686080 18677104 19282663 15798197 17102137 17116885 17582221 19622404 19793801 17384638 18931676 15459660 19101576
ATR FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 27713304 16943440 27094386 22057367 15616588 18077418 18082599 14988723 19101576
ATR ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20616048 15451423 19889979 23144622 17686975 18344416
ATR FANCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 22615860 18677104 19622404 15798197 19793801 12972610 23253856 15136767 19282663 17116885 17582221 14988723 17384638 24095737 18931676 8020957 22266823 19109555 24089143 20832754 26194820 15459660 23444773 19772495 19847258 17296725 11877377 17102137 18550849 21948210 22657828 16697054 19686080 12535671
ATR RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 28666352 23684611 19440044 20860841 18289945 24819595 25520194 19843584 10608806 26057167 17035231 24906880 27908669 22977173 25249630 25070753 26271993 23319600 26212458 29875999 24965470 26474068
ATR BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 26927092 17478428 24746700 15159397 17531442 10866324 18677104 19622404 15798197 19793801 20860841 16713569 11114888 23422745 20936109 16322207 19282663 20068231 17116885 17582221 25879655 10608806 17384638 23346553 12773400 12183412 17525332 15459660 11278964 17296725 11877377 17102137 10550055 16522651
ATR RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18677104 19622404 15798197 19793801 15485915 24842372 20051983 19282663 17116885 17582221 17384638 23273981 18511906 18716619 19490890 15459660 30135856 19357644 17296725 11877377 17102137 25956864
ATR TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17145710 22778941 24395704 28468838 12401524 15159397 24877058 15254178 9733515 11483158 15806145 19056039 11875057 15865930 11551930 11883897 19923893 12548019 18697815 29170437 16293623 19010925 11709713 10446957 9363941 21748595 17272272 22797063 12242661 10196661 22084686 10747897 10608806 10673501 12091386 17118344 23892398 9765199 15489221 24037342 15140942 10435622 17241873 10597277 10801407 11711532 17174997 21593792 25201202 9843217 10606744 15024084 15226429 15922368 21415014 21480565 15585169 24947324 9925639 23380594 9733514 11865061 19625493 16390936 10951572 10570149 23311997 12111733 26144601
ATR EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 18677104 19622404 15798197 19793801 11438669 18756267 19282663 17116885 17582221 17384638 17525332 20019063 15459660 17296725 11877377 15867354 17102137 24705021 18048416
ATR FANCG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 22615860 18677104 19622404 15798197 19793801 12972610 23253856 15136767 19327579 19282663 17116885 17582221 14988723 17384638 24095737 18931676 8020957 22266823 24089143 20832754 15459660 23444773 19772495 19847258 17296725 11877377 17102137 18550849 21948210 22657828 16697054 19686080 12535671
ATR NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17715134 15758953 17526493 18077418
RPA3 ATRIP â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 ATRIP â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP TOPBP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
ATRIP TIPIN â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
ATRIP TIPIN â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
ATRIP CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP TOPBP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
MSH2 ATRIP â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
MSH6 ATRIP â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
MLH1 ATRIP â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
ATRIP CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RPA2 ATRIP â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 ATRIP â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 ATRIP â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 ATRIP â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15743907 12791985 16407120 17339343
ATRIP BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24073851 17616665
BLM RMI1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
BLM FANCG â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM HES1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCC â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM KAT5 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM TOP3A â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12535671 12972610 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18550849 18931676 19217833 19270065 19282663 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCE â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM EXO1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11438669 14676842 15474417 15496928 15549137 15655342 16697054 18001825 18048416 18087292 18171670 18212739 18584027 18756267 18809224 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 20019063 20021983 20064462 22266823 22657828 23253856 24089143 24095737
BLM SUMO3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18708356 15829507 24027577 19956565 25218447
BLM FANCM â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCA â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCE â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM RMI1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
BLM FANCG â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCA â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM TOP3A â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12535671 12972610 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18550849 18931676 19217833 19270065 19282663 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCC â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM HES1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCM â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM WRN â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 22973052 23253856 24089143 24095737
BLM TERF2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 23253856 24089143 24095737
BLM RAP1A â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 23253856 24089143 24095737
BLM FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM POT1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 23253856 24089143 24095737
BLM FEN1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 22973052 23253856 24089143 24095737
BLM TPP1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 23253856 24089143 24095737
BLM TINF2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 23253856 24089143 24095737
BLM RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
RMI1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 15775963 23509288
FANCM BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20347428 20064461
TERF1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17145710 15229185
FANCC BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19622405
CHEK1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21050475 20719863 25015292 25906194 15364958
TERF2 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 15229185 19329795 12181313
BLM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12080066 11399766 22653443 24239288 15806145 11781842 16713569 15364958
BLM CHAF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15143166
BLM FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 19772495 18931676 19847258 22266823 12356323 19622404 16326861 24089143 22973052 23253856 22657828 16697054 24095737 19686080 14688284
BRCA1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 DNA2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 FANCD2 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 XRCC3 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 H2AFX â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 SUMO3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20016603 25218447 20016594 21147198
BRCA1 FANCI â—¼   PHYSICAL_INTERACTION 55.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 FANCD2 â—¼   SHARES_COMPLEX 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 FANCI â—¼   SHARES_COMPLEX 55.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 XRCC3 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 H2AFX â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
BRCA1 DNA2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11877377 15459660 18087291 19342239 19793801 20029420 21060331 21337561
BRCA1 CHEK1 â—¼   REGULATES ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
UIMC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17525341 17525342 17525340 17621610
BRIP1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 22032289 21240188 34591612 18285836 16713569 14576432 17596542 17525342 17525340 15242590 25184681 19369211 18369654 28911102 17581638 15125843 11301010 15133502 19452558 27399284 18717574 17525341 22792074 14576433 20173781 11877378 20681793 14578343
RAD50 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10783165 16260778 16391231 10426999 11504724 25084169 25184681 16713569
BRCA1 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12887909 12485996 11239454 25652403 14499622 16713569
BRCA1 RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 21908405 18285836 16713569 15485915 25310973 9738006 17525342 17525340 16843262 24085845 25184681 26387952 18369654 9811458 16818604 20351172 23416467 19442256 10196224 10910365 19452558 11739404 25252691 10764811 25659039 17965729 11689934
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
DNA2 BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
KAT5 BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RBBP8 BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TOP3A BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
WRN BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RAD50 BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RMI2 BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRIP1 EXO1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRIP1 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TOPBP1 BRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20159562 25374583
RPA1 BRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17596542 19419957
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
CASP3 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10998058 10082566 11684015
CASP3 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11907276 8090205 7596430 9875225 32223133 10438458 17167422 7774019
TOPBP1 CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
CHEK1 RPA3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 TIPIN â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
CHEK1 RPA2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TOPBP1 CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
CHEK1 TIPIN â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
TOPBP1 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
CHEK1 FANCD2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14988723 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801
CHEK1 FANCA â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801
CHEK1 FANCI â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801
CHEK1 FANCG â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801
CHEK1 FANCE â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17296736 17384638 17582221 18677104 18931676 19686080 19793801
CHEK1 RPA3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TP53 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21546904 11158294 20190799 19435816 18632613 15016801 19395378 11152453 18753293
CHEK1 NEK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20090422 19734889 22655267
CHEK1 FANCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17296725 19686080 18677104 15798197 17102137 17116885 17582221 19793801 17384638 18931676 15459660
CHEK1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 26610585 27685627 18285803 22730303 18317453 22705496 29977027 19473886 22665067 25852742 25909291 24847116 24204313 15665856 24238855
CHEK1 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17296725 19686080 22057367 19861535 18677104 15798197 17102137 17116885 17582221 19793801 14988723 17384638 18931676 15459660
CHEK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 20950777 18778462 25545885 18677104 20860841 15798197 19793801 22891162 16511572 23852422 16713569 15865930 11551930 19923893 15467443 11709713 21748595 17116885 15659650 17582221 26384650 10673501 17384638 23966620 23892398 17118344 9765199 15140942 19788416 10801407 18319725 12781359 12897801 25823026 15459660 23296650 15024084 17296725 17102137 11896572 17339337 19933256 20526329 28140789
CHEK1 FANCG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17296725 19686080 18677104 15798197 17102137 17116885 17582221 19793801 17384638 18931676 15459660
CHEK1 FANCE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17296736 17296725 18995830 19686080 27094386 18677104 19473886 15798197 17102137 17116885 17582221 19793801 19061902 17384638 18931676 15459660
COPS5 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25609649 20093369 18926707 10766246 16713569 8837781
NBN DNA2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
DNA2 KAT5 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
DNA2 RAD50 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
PLK1 ECT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17332740 18669648 16247472
PLK1 ERCC6L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17218258 22527115 20360068
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
MSH6 EXO1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20970388 17426132 14676842 16188885 16143102
NBN EXO1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RAD50 EXO1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MSH2 EXO1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20970388 17426132 14676842 16188885 16143102
KAT5 EXO1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TP53BP1 EXO1 â—¼   REGULATES ✅ 21.0 1.0 ACSN 11042216 11438669 11877378 15496928 15549137 15655342 15867354 17243194 18001825 18048416 18171670 18212739 18756267 19217833 19270065 19490890 20019063 20021983 20064462 20646866 9748285
FANCD2 FAN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20603015 21331524 25135477
FANCC FANCA â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCA â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCA â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA HES1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCE â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCA â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCA â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA HES1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCE â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 16116434 12724401 22343915 24451376 11157805 22705371 12239156 12093742 18550849 17396147 15262960 12973351 15082718
FANCA FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22615860 19622404 12972610 23253856 19282663 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCA FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCL FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22615860 19622404 12972610 23253856 19282663 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCB FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCM FANCC â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCC â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 15496928 15549137 15655342 16337602 16697054 17035102 18001825 18157158 18171670 18212739 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19270065 19282663 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC XRCC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 15496928 15549137 15655342 16337602 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 22266823
FANCC TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC HES1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCE â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCC â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCC â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 15496928 15549137 15655342 16337602 16697054 17035102 18001825 18157158 18171670 18212739 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19270065 19282663 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCE â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC HES1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC XRCC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 15496928 15549137 15655342 16337602 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 22266823
FANCC FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 26277624 17145710 24451376 12649160 11157805 16127171 12239156 12093742 18550849 16513431 15262960 14625294
FANCC FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22615860 19622404 12972610 23253856 19282663 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCC FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 22615860 19622404 11751423 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCD2 FANCI â—¼   PHYSICAL_INTERACTION 66.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14614141 14624239 14726013 15242590 15375219 15377654 15459660 15485915 15703371 16337601 16337602 16697054 16713580 16818604 17303408 17349954 17965729 18082604 18082605 18085520 18087292 18448394 18472307 18543256 18584027 18809224 18931676 18995830 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20064462 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
FANCD2 XRCC3 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
FANCD2 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 H2AFX â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 RAD50 â—¼   PHYSICAL_INTERACTION 63.0 1.0 ACSN 10882712 11850621 11877377 12086603 12556884 12607003 14988723 15136767 15175241 15211575 15459660 15498778 15798197 15964794 16163361 16332722 16337602 16531125 16581787 16713580 16805667 16858402 17036055 17102137 17116885 17296725 17303408 17384638 17582221 17713585 17965729 18087292 18171670 18469862 18584027 18677104 18809224 18931676 18995830 19151707 19282663 19342888 19362533 19622404 19654615 19686080 19772495 19793801 19793861 19793862 19805513 19841479 19892829 20051983 20064462 20723763 21376743 22743550 22751496 23444773 24050180 24089143 24095737
FANCD2 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 H2AFX â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 FANCI â—¼   SHARES_COMPLEX 66.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14614141 14624239 14726013 15242590 15375219 15377654 15459660 15485915 15703371 16337601 16337602 16697054 16713580 16818604 17303408 17349954 17965729 18082604 18082605 18085520 18087292 18448394 18472307 18543256 18584027 18809224 18931676 18995830 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20064462 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
FANCD2 RAD50 â—¼   SHARES_COMPLEX 63.0 1.0 ACSN 10882712 11850621 11877377 12086603 12556884 12607003 14988723 15136767 15175241 15211575 15459660 15498778 15798197 15964794 16163361 16332722 16337602 16531125 16581787 16713580 16805667 16858402 17036055 17102137 17116885 17296725 17303408 17384638 17582221 17713585 17965729 18087292 18171670 18469862 18584027 18677104 18809224 18931676 18995830 19151707 19282663 19342888 19362533 19622404 19654615 19686080 19772495 19793801 19793861 19793862 19805513 19841479 19892829 20051983 20064462 20723763 21376743 22743550 22751496 23444773 24050180 24089143 24095737
FANCD2 XRCC3 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
FANCD2 RAD50 â—¼   ENZYMATIC_REACTION ✅ 63.0 1.0 ACSN 10882712 11850621 11877377 12086603 12556884 12607003 14988723 15136767 15175241 15211575 15459660 15498778 15798197 15964794 16163361 16332722 16337602 16531125 16581787 16713580 16805667 16858402 17036055 17102137 17116885 17296725 17303408 17384638 17582221 17713585 17965729 18087292 18171670 18469862 18584027 18677104 18809224 18931676 18995830 19151707 19282663 19342888 19362533 19622404 19654615 19686080 19772495 19793801 19793861 19793862 19805513 19841479 19892829 20051983 20064462 20723763 21376743 22743550 22751496 23444773 24050180 24089143 24095737
FANCG FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCL FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 17396147 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 19622405 18985065 18550849 21948210 22657828 20832754 19686080 12535671
FANCM FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
HES1 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCF FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCE FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 22615860 24451376 12649160 17308347 19622404 12972610 23253856 15136767 19282663 12093742 14988723 8020957 24095737 18931676 26277624 22266823 16697054 24089143 16513431 19704162 23444773 19772495 19847258 15115758 16127171 18550849 21948210 22657828 20832754 19686080 12535671
FANCI FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21719678 22855611 24451376 17460694 27773793 20603015 25168188 19561358 18931676 24623813
FANCG FANCE â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCE â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE HES1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCE â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCE â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE HES1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22615860 19622404 12972610 23253856 19282663 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCM FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 20450923 12649160 11157805 16621732 17082180 11063725 18212739 16720839 15262960
FANCF FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22615860 19622404 12972610 23253856 19282663 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCM FANCG â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG HES1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG XRCC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 15496928 15549137 15655342 16337602 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 22266823
FANCM FANCG â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG XRCC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 15496928 15549137 15655342 16337602 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 22266823
FANCG HES1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22615860 19622404 12972610 23253856 19282663 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
H2AFX FANCI â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCI RAD51 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
H2AFX FANCI â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCI RAD51 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCL FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22615860 19622404 12972610 23253856 19282663 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCL FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 22615860 19622404 12972610 23253856 19282663 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 19622405 18985065 18550849 21948210 22657828 20832754 19686080 12535671
FANCM FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22615860 19622404 12972610 23253856 19282663 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
HES1 FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM HES1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM HES1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
PLK1 FANCM â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
FANCM RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
PLK1 FANCM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18931676 19270156 19622404 19680264 19686080
FBXW7 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14739463 28036276 18930588 16023596
FBXW7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15498494 17145710 32047362 28007894 31569395 33821962 20399964 20970423 17157259 16023596 20852628 15103331 15150404
WRN FEN1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
NBN FEN1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
PARP1 FEN1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
RPA2 FEN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
RPA1 FEN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
RPA3 FEN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
FEN1 RBBP8 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
WRN FEN1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
WRN FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 14657243 12356323 11598021 16326861 10893179 14688284
TP53 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16432214 20080630 17242190 20422012
PARP1 H2AFX â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 12607003 14726013 15175241 15459660 15703371 16581787 16697054 17088286 17116881 17303408 17713585 19208614 19364882 19772495 19847258 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9488723
H2AFX RAD51 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
H2AFX RAD50 â—¼   PHYSICAL_INTERACTION 73.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15496928 15549137 15655342 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001825 18006705 18087292 18171670 18212739 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20051983 20064462 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
H2AFX RAD51 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
H2AFX RAD50 â—¼   SHARES_COMPLEX 73.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15496928 15549137 15655342 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001825 18006705 18087292 18171670 18212739 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20051983 20064462 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
RNF8 H2AFX â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 12607003 15279786 15459660 15496928 15549137 15655342 17303408 17660363 18001825 18006705 18171670 18212739 18583988 18590585 18678709 18678890 18809224 19217833 19270065 19490890 19772495 20021983 20064462 7575488 9407949
H2AFX RAD50 â—¼   ENZYMATIC_REACTION ✅ 73.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15496928 15549137 15655342 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001825 18006705 18087292 18171670 18212739 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20051983 20064462 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
HERC2 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
HERC2 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
HERC2 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
HERC2 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
HERC2 RNF168 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20023648
HERC2 RNF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20023648 22508508 25305019 22814251
HES1 TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
UBE2I JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11877416 16713569 16055711 10788439 8733011
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
RIF1 KAT5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
WRN KAT5 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TOP3A KAT5 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
PAXIP1 KAT5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
KAT5 RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
KAT5 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
KAT5 RBBP8 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
KAT5 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
KAT5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12776177 19150978 15572685 34650217
MSH2 MSH6 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11307145 11948476 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 16879101 17129768 17303408 17395641 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261 23507534
MSH2 MUS81 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
MSH2 MSH6 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11307145 11948476 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 16879101 17129768 17303408 17395641 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261 23507534
MSH2 MUS81 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
UBE2I MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11779867 16713569 22910413
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 20940401
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
NBN RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
NBN PARP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
NBN UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
NBN RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NBN TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
PARP1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 WRN â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15211575 15385537 15385968 15498778 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19654615 19748837 19847258 19892829 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24089143 24095737 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 RBBP8 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
PARP1 SUMO3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19779455 25218447 23750026 24782567
PARP1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 WRN â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15211575 15385537 15385968 15498778 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19654615 19748837 19847258 19892829 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24089143 24095737 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 WRN â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15211575 15385537 15385968 15498778 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19654615 19748837 19847258 19892829 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24089143 24095737 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
RIF1 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RNF8 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 PAXIP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
PAXIP1 RNF168 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
TP53BP1 PAXIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19414588 15456759 17690115 14576432 19481982
PAXIP1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14576432 15456759 19481982 19414588
PLK1 TERF1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 18625707 18931676 19270156 19622404 19686080 21818122 22433952 22634377 8127874
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 TOP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 25328138 8939955 11699638 19098900 18062778 18171681 7499337 7961967 29915179
PLK1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20126263 25607646 24703952
PLK1 TERF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18625707
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
RAP1A POT1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TINF2 POT1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
POT1 TERF2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
POT1 TPP1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
RAP1A POT1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TINF2 POT1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
POT1 TERF2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
POT1 TPP1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
WRN POT1 â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11283614 12202749 12545156 15155580 15385537 16449207 17055429 17116323 17550342 17965729 18398454 18524993 18558713 18584027 18809224 19490890 20027199 20064462 20691907 20713526 20818389 21376743 21733352 2191300 21919891 22657828 22743550 23082994 23140366 23161013 23253856 23869868 24036544 24050180 24709898 9618481
RIF1 RAD50 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
TOP3A RAD50 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
XRCC6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
WRN RAD50 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
RAD50 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RAD50 RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RAD50 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
WRN RAD50 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
RAD51 XRCC3 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 XRCC3 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
TP53 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513613 16322760 20802511 16398215 18769160
RAD52 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15766559 17145710 9826763 20190268 17118963 10666456 12750383 9837724 19338310 10448035 10212258
XRCC3 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9660962 23438602 28864920 11842113
TP53 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 8617246 11002423 16713569 16322760 16983346 9380510
RPA2 RAD52 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 11571269 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17582221 17884153 18677104 19473888 19772495 19793801 19809470 19847258 20081207
XRCC3 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
XRCC3 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
WRN RAD52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 12750383 12919958 17118963
RAP1A TPP1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
RAP1A TINF2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
RAP1A TERF2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
RAP1A TERF2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
RAP1A TINF2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
RAP1A TPP1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
WRN RAP1A â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11283614 12202749 12545156 15155580 15385537 16449207 17055429 17116323 17550342 17965729 18398454 18524993 18558713 18584027 18809224 19490890 20027199 20064462 20691907 20713526 20818389 21376743 21733352 2191300 21919891 22657828 22743550 23082994 23140366 23161013 23253856 23869868 24036544 24050180 24709898 9618481
TOP3A RBBP8 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
WRN RBBP8 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RMI2 RBBP8 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RBBP8 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
SIRT6 RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20829486
TP53BP1 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RNF8 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RIF1 RNF168 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
TP53BP1 RIF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15342490 23333305 29203878
TOP3A RMI1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
TOP3A RMI1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
XRCC6 RNF168 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RNF168 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RNF8 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RNF8 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RNF8 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 18001824 18006705 19203579 19772495
TIPIN RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 TOPBP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
TIPIN RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 TOPBP1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 TOPBP1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 14499497 24126761 24332808 10373438 15735006 15965237 26474068 14734561
TIPIN RPA2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RPA3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 TOPBP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RPA3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
TIPIN RPA2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 TOPBP1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN RPA2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 TOPBP1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN RPA3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 TOPBP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN RPA3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 TOPBP1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN RPA3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 TOPBP1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TOP1 SUMO1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12149243 11709553 25114211 10759568
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
TOP2A SUMO2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24782567 17183683 18381449 25114211
TOP2A SUMO3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24782567 17183683 18381449 25114211
TINF2 TERF2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TERF2 TPP1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TINF2 TERF2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TERF2 TPP1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
WRN TERF2 â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11283614 12202749 12545156 15155580 15385537 16449207 17055429 17116323 17550342 17965729 18398454 18524993 18558713 18584027 18809224 19490890 20027199 20064462 20691907 20713526 20818389 21376743 21733352 2191300 21919891 22657828 22743550 23082994 23140366 23161013 23253856 23869868 24036544 24050180 24709898 9618481
TERF2 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 15665826 18212065 12181313
TINF2 TPP1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TINF2 TPP1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
WRN TINF2 â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11283614 12202749 12545156 15155580 15385537 16449207 17055429 17116323 17550342 17965729 18398454 18524993 18558713 18584027 18809224 19490890 20027199 20064462 20691907 20713526 20818389 21376743 21733352 2191300 21919891 22657828 22743550 23082994 23140366 23161013 23253856 23869868 24036544 24050180 24709898 9618481
WRN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12080066 11399766 15735006 16713569 11427532
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
TP53 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12080066 11399766 15735006 16713569 11427532
XRCC6 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
TP53BP1 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
TP53BP1 UIMC1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
WRN TPP1 â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11283614 12202749 12545156 15155580 15385537 16449207 17055429 17116323 17550342 17965729 18398454 18524993 18558713 18584027 18809224 19490890 20027199 20064462 20691907 20713526 20818389 21376743 21733352 2191300 21919891 22657828 22743550 23082994 23140366 23161013 23253856 23869868 24036544 24050180 24709898 9618481
UBE2I UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19549727 17698038
EXO1 PIF1 â—¼   KO_UP_REGULATES ✅ + 1.16 1.16 PKG 28854368
EXO1 PLK1 â—¼   KO_UP_REGULATES ✅ + 1.21 1.21 PKG 28854368
RNF8 RPS27 â—¼   KO_DOWN_REGULATES ✅ - -1.57 1.56 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
MSH6 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -4.08 4.07 PKG 28854368
MSH2 MSH6 â—¼   KO_DOWN_REGULATES ✅ - -5.11 5.1 PKG 28854368
MSH6 MSH6 â—¼   KO_DOWN_REGULATES ✅ - -5.12 5.11 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368