Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NBN ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BLM ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0706013104 17686975
BLM ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
NBN ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
POLR2C INTS10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
POLR2C INTS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
POLR2C INTS12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
SMAD3 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
NFKB1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18031796
POLR2C INTS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
POLR2A CTDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216783 14576432
POLR2B CTDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15670829
POLR2C POLR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
POLR2C POLR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
CTDP1 POLR2G â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
INTS3 NABP1 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
POLR2H POLR2J â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
INTS1 INTS12 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
C7orf26 INTS7 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
INTS6 PPP2R1A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
INTS7 INTS9 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
INTS6 INTS7 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
INTS2 INTS5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
INTS5 INTS8 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
INTS5 INTS6 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CPSF3L INTS2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
INTS2 INTS6 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
INTS4 INTS6 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CPSF3L INTS6 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
INTS6 INTS9 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
INTS6 INTS8 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
INTS1 INTS8 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CTDP1 POLR2E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CTDP1 POLR2J â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
INTS1 INTS6 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
NBN BLM â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29523790 10783165
INTS1 INTS4 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
ATR TP53BP1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
INTS7 PPP2CA â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
INTS8 PPP2CA â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CPSF3L INTS5 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
CPSF3L INTS1 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
INTS1 INTS9 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
ASUN INTS1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ATR ATRIP â—¼   PHOSPHORYLATION ✅ + 0.88 0.88 Signor 15451423
INTS1 INTS5 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
INTS5 PPP2CA â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ATR NBN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17526493 10608806 15758953 23368512
INTS2 PPP2CA â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
PPP2R1B PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8392071 8286818
INTS4 PPP2CA â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
ASUN VWA9 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ATRIP ATR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19097996 28514442 19889979 17384638 15758953 14724280 15451423 23144622 26854234 21285353 18344416 20847938 20616048 15743907 14657349 11721054 15538388 17686975 18162465 17526493 33961781 15210935 18283122
AKT1 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 23397142
SMAD3 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 16189514 25514493 11927552 28443643 21988832 20211142 15084259 12732634 19768112 15467747 20142324 25609649 15922743 12917407 12419246 20564330 24382352 19139564 32296183 24157709 18729074 22442258 10092624 17283070 15350224 17591701 15761153 31591477 10995777 26555259 9892009 9311995 15588252 12167862 10878024 25910212 27703004 33990575 28115363 18055455 22310290 19135894 10531362 12794086 15231748 21297662 22045334 19917253 24584437 27107012 29892012 29997244 21532621 27845895 21597466 25502805 11114293 12543979 23788427
AKT1 SMAD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 25241761
PPP2R1A PPP2CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15936019 16039140
CPSF3L PPP2CA â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
INTS9 PPP2CA â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
UBE2N UBA1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 31638574 14517261 18678647 25527291 27173435 30097011 33619271 27182664 29537486
INTS11 INTS9 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
UBA1 UBE2N â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
PPP2R1A PPP2CB â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217765 15936019
INTS6 PPP2CA â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
INTS1 PPP2CA â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CTDP1 POLR2B â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
INTS4 INTS9 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
ATR BLM â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
INTS1 INTS2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
INTS4 INTS5 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
CPSF3L INTS4 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
BLM TP53BP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
INTS5 INTS9 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
INTS1 INTS7 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
PPP2CB PPP2R1B â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
INTS7 INTS8 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
INTS2 INTS8 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
INTS5 INTS7 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CPSF3L INTS7 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
POLR2D POLR2H â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
INTS3 NABP2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
INIP INTS3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
INTS2 INTS7 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
INIP NABP2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CPSF3L INTS9 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
POLR2E POLR2J â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
POLR2A POLR2J â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CTDP1 POLR2A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
POLR2G POLR2J â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
POLR2D POLR2J â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1A PPP2R1B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
POLR2D POLR2E â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2C POLR2D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2D POLR2G â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2B POLR2J â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CB PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2E POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2B POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2A POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2G POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2C POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2B POLR2D â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2A POLR2D â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2B POLR2G â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2A POLR2B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATR ATRIP â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR ATRIP â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
BLM ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
ATR ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20616048 15451423 19889979 23144622 17686975 18344416
ATR NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17715134 15758953 17526493 18077418
NBN BLM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
UBE2N TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 17349954 17652783 18196958 19203579 19258535 19793861 19793862 19841479 19851286 22771115
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
POLR2C POLR2J â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   PROTEIN_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
PPP2CA SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20704570 23331499 19951945
AKT1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 25241761 15104092 16362038 21071413 18988627 26297431 15048128
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
PPP2CB AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15367694 11087733 18039929 19216069 18077353 19556239 19996169 10026142 10995457 18042541 20452955 18559511 8650155 18588945 16680151 11812651 20360384 16406523
PPP2R1B PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18715871 17540176 19114990
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
POLR2B POLR2E â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2A POLR2E â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2C POLR2E â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2E POLR2G â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2A POLR2C â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2B POLR2C â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2C POLR2G â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2A POLR2G â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105