KAT5
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
ATR
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
MRE11
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
MRE11
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
MRE11
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21052091
8081463
|
RAD50
|
MRE11
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7114538
19197236
|
ATM
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
ATM
|
HERC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20023648
|
NBN
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
RPA3
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
BLM
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
DNA2
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
RPA1
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
BRCA1
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
TOP3A
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
BRCA1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
23422745
|
ATR
|
HERC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20023648
|
TOP3A
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
BLM
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
DNA2
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
NBN
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
XRCC3
|
BLM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
RAD51C
|
BLM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
TP53BP1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15970701
21914189
|
RPA2
|
DNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18593712
23604072
|
RPA1
|
DNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18593712
23604072
|
RPA3
|
DNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18593712
23604072
|
TOP3A
|
FANCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8140640
21240188
|
RAD50
|
NBN
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7114538
19197236
|
RAD51C
|
TOP3A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
RAD51C
|
RMI1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
RAD51C
|
RMI2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
XRCC3
|
RMI1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
RMI1
|
RMI2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
XRCC3
|
RMI2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
XRCC3
|
TOP3A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
BLM
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
ATM
|
RBBP8
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.8
|
0.8
|
Signor
|
10910365
|
RAD50
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
18854157
|
ATM
|
RAD50
|
â—¼ PHOSPHORYLATION
|
|
|
0.8
|
0.8
|
Signor
|
17570479
|
RAD50
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
10426999
|
RAD18
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
MRE11
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
24981860
|
BRCA1
|
ETAA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29656893
27723720
|
BLM
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
BRCA1
|
RAD18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25184681
29656893
23901102
|
CDCA5
|
INCENP
|
â—¼ CORRELATES
|
|
+
|
0.83
|
0.83
|
CCLE
|
31978347
|
BRCA1
|
RBBP8
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
16818604
|
RBBP8
|
BRCA1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
24832651
|
ATM
|
NBN
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
10802669
|
HERC2
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
BLM
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.83
|
STRING
|
36370105
|
RAD50
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25084169
10783165
29523790
|
FANCA
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
22705371
12973351
23509288
22343915
12724401
|
BLM
|
TOP3A
|
â—¼ COLOCALIZATION
|
✅
|
|
0.85
|
0.85
|
mint
|
20711169
8048867
|
TOP3A
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
20826342
20711169
26186194
20826341
28514442
|
BRCA1
|
FANCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
NBN
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10783165
29523790
|
ATR
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
ATRIP
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
RMI2
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
BLM
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
ATM
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ATR
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
ATM
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10783165
15758953
10608806
|
MRE11
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10783165
28506294
29523790
|
ATM
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
BRCA1
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
25084169
29656893
26831064
10783165
|
ATR
|
ATRIP
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.88
|
0.88
|
Signor
|
15451423
|
NBN
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
BRCA1
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17616665
29656893
24073851
|
NBN
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10426999
29656893
10783165
11504724
25659039
25939603
25184681
19244116
18171670
12124328
|
FANCM
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
RPA3
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
BARD1
|
DNA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
16697054
19772495
19847258
|
RPA2
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
BRCA1
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10426999
11353843
17349954
23530059
24413181
16391231
29656893
11504724
25184681
10783165
|
NBN
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12750284
12419185
24413181
21884979
24981860
22939629
12679336
10426999
28369484
17526493
9705271
26455393
12607003
17612497
12447395
22464731
22078559
22231403
34348893
28363998
11062235
15758953
11238951
23530059
33558481
15734743
34038735
30179224
12861053
18458108
19270065
17500065
10783165
30440001
22941933
19244116
|
RBBP8
|
MRE11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17965729
21052091
|
RPA3
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
KAT5
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16141325
|
ATRIP
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
17686975
14657349
15210935
17384638
20616048
17526493
18162465
21285353
26854234
19097996
18283122
15743907
15451423
14724280
15538388
28514442
23144622
15758953
19889979
18344416
20847938
11721054
|
RMI1
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20360068
20064461
20826342
23509288
26496610
24239288
20711169
15775963
|
BRIP1
|
BLM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21240188
|
FANCA
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12354784
29656893
16713569
21240188
|
RPA2
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
NBN
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
NBN
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
RPA3
|
â—¼ CORRELATES
|
|
+
|
0.9
|
0.9
|
CCLE
|
31978347
|
ATR
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
ATM
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
BLM
|
RMI1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
20711169
8048867
|
APITD1
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
APITD1
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
APITD1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
BLM
|
C17ORF70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
C17ORF70
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
C17ORF70
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
C17ORF70
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
FANCA
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
ATM
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
RPA1
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
RPA3
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
24126761
|
FANCM
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
RAD51C
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
BLM
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
NBN
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ATR
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.94
|
STRING
|
36370105
|
BLM
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
DNA2
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
ATM
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
RAD50
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
24981860
19197236
22939629
12679336
10426999
26344197
17526493
9705271
12607003
17612497
12447395
22464731
34348893
11062235
15758953
12124328
11238951
26215093
23530059
15734743
16391231
24651726
30179224
17500065
30440001
22941933
10783165
|
FANCM
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
RMI1
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
RAD18
|
TP53BP1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.98
|
0.97
|
PKG
|
28854368
|
BRIP1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5220047
17581638
|
BLM
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
BRCA1
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
BRCA1
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
RPA1
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
RAD50
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
12750284
24413181
24981860
19197236
22939629
31501894
30733337
10508516
26344197
8756642
28369484
9705271
26455393
12607003
16163361
11504724
34348893
28363998
11062235
26215093
27173435
23530059
33558481
15734743
16391231
24651726
17694070
34038735
17500065
19270065
30179224
10888888
10783165
|
RMI1
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
APITD1
|
C17ORF70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
APITD1
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
APITD1
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
APITD1
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
APITD1
|
FANCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
C17ORF70
|
FANCM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
C17ORF70
|
FANCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
FANCA
|
FANCM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
FANCA
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
RPA1
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
BARD1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
APITD1
|
FANCM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
FANCM
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
RMI2
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RAD50
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
NBN
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
MRE11
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
TOP3A
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BRCA1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
DNA2
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BLM
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BARD1
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BARD1
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BARD1
|
XRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
TP53BP1
|
BARD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
BARD1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
99.0
|
1.0
|
Omnipath
|
16403807
16391231
28262780
15159397
25652403
26350354
26490435
14647430
11927591
25184681
16713569
11526114
35203293
9738006
12732733
24289923
11573085
18936166
23086937
24085845
12890688
15855157
24695549
19369211
9798686
11257228
11498787
12700228
11925436
10477523
19176389
23680151
25634209
23416467
34726323
29355525
18369654
14636569
11504724
12951069
19117993
20060929
17873885
14638690
18493658
11278247
15184379
22110403
11301010
11773071
12431996
10635334
20029420
9788437
17664283
21901007
25252691
12485996
10026184
12438698
17525341
16489000
8944023
15265711
12419249
20681793
9342365
27239795
20215511
25823446
19916563
|
MRE11
|
DNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
MRE11
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
MRE11
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
MRE11
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
MRE11
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
MRE11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19709933
26240375
17570479
31353207
10608806
|
RAD50
|
MRE11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19197236
16163361
10888888
8756642
17713585
|
MRE11
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
22464731
26455393
12861053
17500065
15734743
12419185
19270065
22078559
19244116
21884979
12679336
11238951
12607003
9705271
17713585
10783165
12447395
10426999
18458108
15758953
|
DNA2
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BLM
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BRCA1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
100.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12086603
12202749
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
100.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12086603
12202749
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
RPA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
RAD50
|
â—¼ REGULATES
|
✅
|
|
100.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12086603
12202749
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATR
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15510216
10608806
17478428
17124492
|
ATM
|
FANCA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17525332
19109555
|
ATM
|
RPA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17525332
11359916
|
ATM
|
RPA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
29875999
15964794
11877377
17303408
9725899
16163361
14872059
23847781
9139719
10713094
9295339
20860841
16731533
12607003
22977173
7171818
15459660
|
ATM
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
80.0
|
1.0
|
Omnipath
|
12433983
12861053
17485521
23146902
10839545
19413330
15302935
27602502
17429352
19523210
24360018
20068231
17507690
17570479
10608806
12598907
18669648
25088203
18003706
11252893
17431132
23097684
10766245
12814430
10802669
21664921
26512707
10839544
11927276
21130714
17525332
12447395
14707289
15733840
15279770
25119968
18644472
28822740
|
ATM
|
BLM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16199871
11146546
25766002
17984114
14643436
20719863
17363339
14729972
18054789
12034743
30496191
16880735
11375976
|
ATM
|
TP53BP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
11042216
17940005
26247731
18996087
19876065
16945145
12447390
22621922
18644834
19650866
24320053
18077418
17570479
17690115
17525332
12697768
|
ATM
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
26927092
17303408
15159397
24746700
12024016
10866324
30197789
12919958
11114888
26745677
26383678
34301763
12427729
11313470
16163361
28035057
20068231
25939603
26320175
17570479
19683496
22743550
10608806
23802008
23847781
21203981
15964794
12183412
12607003
17525332
19996295
15459660
11278964
19651622
21706030
11877377
20952512
10373534
19622773
10550055
27170701
15212693
23704879
|
ATM
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
23468639
23675572
17570479
24837676
10910365
16249056
11689934
10608806
17525332
22743550
|
ATM
|
RAD50
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17570479
17081983
15302935
|
RPA2
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
61.0
|
1.0
|
ACSN
|
10884395
11756412
11877377
12086603
12466554
12766152
12875843
14614141
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15242590
15375219
15377654
15459660
15485915
15703371
15743907
15798197
16530042
16697054
16713580
16805667
16818604
16880517
16885023
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
17855402
18157158
18451105
18469862
18543256
18677104
18931676
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
19686080
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
11850621
11877377
12086603
12607003
14988723
15136767
15175241
15459660
15798197
16713580
16805667
17102137
17116885
17296725
17384638
17582221
18087292
18469862
18584027
18677104
18809224
18931676
18995830
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
22751496
23444773
24050180
|
ATR
|
FANCM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
52.0
|
1.0
|
ACSN
|
11877377
12086603
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15175241
15189446
15459660
15798197
16337602
16697054
16713580
16805667
17035102
17102137
17116885
17296725
17384638
17582221
18157158
18448394
18469862
18472307
18550849
18677104
18931676
18995830
19217833
19225445
19258535
19282663
19342888
19622404
19686080
19772495
19793801
19847258
20051983
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
ATR
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
11850621
11877377
12086603
12607003
14988723
15136767
15175241
15459660
15798197
16713580
16805667
17102137
17116885
17296725
17384638
17582221
18087292
18469862
18584027
18677104
18809224
18931676
18995830
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
22751496
23444773
24050180
|
ATR
|
ATRIP
|
â—¼ SHARES_COMPLEX
|
|
|
61.0
|
1.0
|
ACSN
|
10884395
11756412
11877377
12086603
12466554
12766152
12875843
14614141
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15242590
15375219
15377654
15459660
15485915
15703371
15743907
15798197
16530042
16697054
16713580
16805667
16818604
16880517
16885023
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
17855402
18157158
18451105
18469862
18543256
18677104
18931676
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
19686080
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
FANCM
|
â—¼ SHARES_COMPLEX
|
|
|
52.0
|
1.0
|
ACSN
|
11877377
12086603
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15175241
15189446
15459660
15798197
16337602
16697054
16713580
16805667
17035102
17102137
17116885
17296725
17384638
17582221
18157158
18448394
18469862
18472307
18550849
18677104
18931676
18995830
19217833
19225445
19258535
19282663
19342888
19622404
19686080
19772495
19793801
19847258
20051983
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
ATR
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
42.0
|
1.0
|
ACSN
|
11438669
11877377
14988723
15136767
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18511906
18543256
18677104
18716619
18756267
18931676
18995830
19004803
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
9488723
9858600
|
ATR
|
FANCA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
70.0
|
1.0
|
ACSN
|
11438669
11877377
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
15459660
15485915
15798197
15867354
16332722
16337602
16540648
16697054
16713580
16731533
16885023
17035102
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18157158
18448394
18469862
18472307
18511906
18543256
18550849
18677104
18716619
18756267
18931676
18995830
19004803
19217833
19225445
19258535
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
19847258
20019063
20051983
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
9488723
9858600
|
RPA2
|
ATR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RPA1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RPA3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
BLM
|
ATR
|
â—¼ UP_REGULATES
|
✅
|
+
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
ATR
|
FANCM
|
â—¼ UP_REGULATES
|
✅
|
+
|
52.0
|
1.0
|
ACSN
|
11877377
12086603
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15175241
15189446
15459660
15798197
16337602
16697054
16713580
16805667
17035102
17102137
17116885
17296725
17384638
17582221
18157158
18448394
18469862
18472307
18550849
18677104
18931676
18995830
19217833
19225445
19258535
19282663
19342888
19622404
19686080
19772495
19793801
19847258
20051983
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
ATR
|
FANCA
|
â—¼ UP_REGULATES
|
✅
|
+
|
70.0
|
1.0
|
ACSN
|
11438669
11877377
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
15459660
15485915
15798197
15867354
16332722
16337602
16540648
16697054
16713580
16731533
16885023
17035102
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18157158
18448394
18469862
18472307
18511906
18543256
18550849
18677104
18716619
18756267
18931676
18995830
19004803
19217833
19225445
19258535
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
19847258
20019063
20051983
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
9488723
9858600
|
RPA2
|
ATR
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RPA1
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RPA3
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
XRCC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23438602
26354865
|
ATR
|
ATRIP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20616048
15451423
19889979
23144622
17686975
18344416
|
ATR
|
FANCA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
22615860
18677104
19622404
15798197
19793801
12972610
23253856
15136767
19282663
17116885
17582221
14988723
17384638
24095737
18931676
8020957
22266823
19109555
24089143
20832754
26194820
15459660
23444773
19772495
19847258
17296725
11877377
17102137
18550849
21948210
22657828
16697054
19686080
12535671
|
ATR
|
RPA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
28666352
23684611
19440044
20860841
18289945
24819595
25520194
19843584
10608806
26057167
17035231
24906880
27908669
22977173
25249630
25070753
26271993
23319600
26212458
29875999
24965470
26474068
|
ATR
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
26927092
17478428
24746700
15159397
17531442
10866324
18677104
19622404
15798197
19793801
20860841
16713569
11114888
23422745
20936109
16322207
19282663
20068231
17116885
17582221
25879655
10608806
17384638
23346553
12773400
12183412
17525332
15459660
11278964
17296725
11877377
17102137
10550055
16522651
|
ATR
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
18677104
19622404
15798197
19793801
15485915
24842372
20051983
19282663
17116885
17582221
17384638
23273981
18511906
18716619
19490890
15459660
30135856
19357644
17296725
11877377
17102137
25956864
|
ATR
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17715134
15758953
17526493
18077418
|
RPA3
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA2
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA1
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA2
|
ATRIP
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA1
|
ATRIP
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA3
|
ATRIP
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA3
|
ATRIP
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA1
|
ATRIP
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA2
|
ATRIP
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA1
|
ATRIP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15743907
12791985
16407120
17339343
|
ATRIP
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24073851
17616665
|
BLM
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
15496928
15549137
15655342
16537486
16595695
16697054
18001825
18171670
18212739
18931676
19217833
19270065
19490890
19622404
19686080
19772495
19847258
19945966
20021983
20064462
20826342
22266823
22657828
23253856
24089143
24095737
|
BLM
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BLM
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
12535671
12972610
15496928
15549137
15655342
16537486
16595695
16697054
18001825
18171670
18212739
18550849
18931676
19217833
19270065
19282663
19490890
19622404
19686080
19772495
19847258
19945966
20021983
20064462
20826342
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
BLM
|
FANCM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
BLM
|
FANCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
BLM
|
RMI1
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
15496928
15549137
15655342
16537486
16595695
16697054
18001825
18171670
18212739
18931676
19217833
19270065
19490890
19622404
19686080
19772495
19847258
19945966
20021983
20064462
20826342
22266823
22657828
23253856
24089143
24095737
|
BLM
|
FANCA
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
BLM
|
TOP3A
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
12535671
12972610
15496928
15549137
15655342
16537486
16595695
16697054
18001825
18171670
18212739
18550849
18931676
19217833
19270065
19282663
19490890
19622404
19686080
19772495
19847258
19945966
20021983
20064462
20826342
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
BLM
|
FANCM
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
BLM
|
RAD50
|
â—¼ UP_REGULATES
|
✅
|
+
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
RMI1
|
BLM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
15775963
23509288
|
FANCM
|
BLM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
20347428
20064461
|
BLM
|
CHAF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15143166
|
BRCA1
|
DNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BRCA1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
BRCA1
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BRCA1
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BRCA1
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BRCA1
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
XRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
TP53BP1
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
BRCA1
|
DNA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
18087291
19342239
19793801
20029420
21060331
21337561
|
BRIP1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
22032289
21240188
34591612
18285836
16713569
14576432
17596542
17525342
17525340
15242590
25184681
19369211
18369654
28911102
17581638
15125843
11301010
15133502
19452558
27399284
18717574
17525341
22792074
14576433
20173781
11877378
20681793
14578343
|
RAD50
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10783165
16260778
16391231
10426999
11504724
25084169
25184681
16713569
|
BRCA1
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
21908405
18285836
16713569
15485915
25310973
9738006
17525342
17525340
16843262
24085845
25184681
26387952
18369654
9811458
16818604
20351172
23416467
19442256
10196224
10910365
19452558
11739404
25252691
10764811
25659039
17965729
11689934
|
DNA2
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
NBN
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
KAT5
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RBBP8
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
TOP3A
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RAD50
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RMI2
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BRIP1
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RPA1
|
BRIP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17596542
19419957
|
NBN
|
DNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
DNA2
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
DNA2
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
FANCM
|
FANCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
FANCA
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
12535671
12972610
16697054
18550849
18931676
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
FANCM
|
FANCA
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
FANCA
|
TOP3A
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
12535671
12972610
16697054
18550849
18931676
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
FANCA
|
RAD50
|
â—¼ UP_REGULATES
|
✅
|
+
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
FANCM
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
12535671
12972610
16697054
18550849
18931676
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
FANCM
|
TOP3A
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
12535671
12972610
16697054
18550849
18931676
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
FANCM
|
RAD50
|
â—¼ UP_REGULATES
|
✅
|
+
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
TOP3A
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
KAT5
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
KAT5
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
KAT5
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
NBN
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
NBN
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
NBN
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RPA3
|
RAD18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
RPA2
|
RAD18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
RPA1
|
RAD18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
RAD18
|
RAD51C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19396164
|
TOP3A
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RAD50
|
RMI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RAD50
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
TOP3A
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RMI2
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RBBP8
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
TOP3A
|
RMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
15496928
15549137
15655342
16537486
16595695
16697054
18001825
18171670
18212739
18931676
19217833
19270065
19490890
19622404
19686080
19772495
19847258
19945966
20021983
20064462
20826342
22266823
22657828
23253856
24089143
24095737
|
TOP3A
|
RMI1
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
15496928
15549137
15655342
16537486
16595695
16697054
18001825
18171670
18212739
18931676
19217833
19270065
19490890
19622404
19686080
19772495
19847258
19945966
20021983
20064462
20826342
22266823
22657828
23253856
24089143
24095737
|
RPA2
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA1
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA3
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RAD18
|
DNA2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.03
|
1.02
|
PKG
|
28854368
|
RAD18
|
RMI2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.94
|
1.94
|
PKG
|
28854368
|
ATM
|
ATM
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.25
|
2.25
|
PKG
|
28854368
|
RAD18
|
RAD18
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-4.39
|
4.38
|
PKG
|
28854368
|
NBN
|
NBN
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-6.31
|
6.3
|
PKG
|
28854368
|
TP53BP1
|
TP53BP1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-9.54
|
9.53
|
PKG
|
28854368
|