Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
CHEK2 NSD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
NSD2 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
NSD2 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
NSD2 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
NSD2 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
CHEK2 NSD2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 H2AX â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
H2AX SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
H2AX H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
H2AX UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H2AX SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H2AX DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
CHEK2 H2AX â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
H2AX ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19146767 11673449
ATM H2AX â—¼   COLOCALIZATION 2.0 0.8 intact 16858402 5218840
BICD2 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CEP290 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CHEK2 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
SUMO1 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
BRCA1 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9008167 19146767
UBE2I H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H4C6 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
SUMO2 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
H3-4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
H3-4 USP19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 MRE11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 HOOK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CHEK2 H3-4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
ATR H3-4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19146767 11673449
H3-4 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16774833
KAT5 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ATR BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
PIAS4 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ATRIP BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TP53 BARD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14636569 15782130
CHEK2 MRE11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
MRE11 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
MRE11 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
MRE11 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
MRE11 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
MRE11 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
MRE11 ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
CHEK2 MRE11 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
RAD50 MRE11 â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
CHEK2 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
KDM4B H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22373579 8387631
SUMO2 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
H4C6 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16628214 5218530
H4C6 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H4C6 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H4C6 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H4C6 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
H4C6 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHEK2 H4C6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
H4C6 ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19146767 11673449
H4C6 SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
CHEK2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
SUMO1 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
CHEK2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
MDM2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19816404 21986495
ATM HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
NBN ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
RPA3 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BLM ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
RPA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BRCA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TOP3A ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR RMI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TP53 ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9925639 10435622
ATR BRCA1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 23422745
ATR HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
TOP3A ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BLM ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
NBN ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
WRN ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP RMI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TP53 ATRIP â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9925639 10435622
XRCC5 ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18285803
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
LRRK2 AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
BDKRB2 HERC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
TP53 BDKRB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15632413 10748162
TP53 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
ESR1 BLM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17268063
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
BMI1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6948569 19233177
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
PIAS4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21113239
C5AR2 HERC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CDC14B MAPK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18235225 20236090
RIF1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 CHCHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HERC2 CHEK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
RNF8 CHEK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
NBN CHEK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 UBE2V2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
RNF8 CHEK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
HERC2 CHEK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
NBN CHEK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 UBE2V2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 PIAS4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 RAD50 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 UBE2N â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 MDC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 RNF168 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 KAT5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 MDM2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15862297 5217705
CHMP4B UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KAT5 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
HERC2 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
MDC1 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
UBE2N DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
TP53BP1 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
RAD50 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
RNF168 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
RIF1 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
UBE2V2 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
RNF8 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
NBN DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
PAXIP1 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
PIAS4 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
EIF3E EIF3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18599441 0801313105
EIF3M EIF3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18599441 0801313105
EIF3L EIF3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18599441 0801313105
EIF3K EIF3E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18599441 0801313105
EIF3E KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC EIF3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6613251 18354498
EIF3M EIF3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EIF3I EIF3G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219314 17094969
EIF3M EIF3H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18599441 0801313105
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
UBC FTH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219290 17082767
RPL13 HERC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HERC2 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
MITF HERC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22234890
PRKDC HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
TP53 HLA-A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15501971 12857899
UBE2I KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KAT5 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SIRT1 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20100829
KDM4A UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KDM4A SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KDM4B UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KDM4B SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
TP53 KDM4B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28073943
KRT77 KRT17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RYBP LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP1LC3A PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
MAP1LC3B SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18296641 0712145105
SUMO1 MDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
UBE2I MDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
UBE2I MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12393906 20972456
SUMO1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12393906 11384992
UIMC1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19433585
MITF OCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22234890
NBN SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
NBN SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
NBN UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RAD50 NBN â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
TP53 PAXIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
PHKA2 PHKG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10487978 32296183
UBE2I PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
XRCC6 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
SUMO2 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
XRCC5 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PPP5C TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19176521
XPA PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0915085107 20304803
PRKDC RNF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SUMO1 RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
UBE2I RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO2 RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RPA2 RIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 UBE2V2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
UBE2I RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RNF8 RNF168 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20385750
RNF8 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RNF8 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RPA1 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 20705237
RPA1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 20705237
SIRT3 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18710944
TP53 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
TP53 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23995788 21317932
SUMO1 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20016603 25114211
TP53 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11420669 21187340
SUMO1 UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17698038
UBE2N SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO2 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1004248107 20534433
SUMO2 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO2 UBE2V2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
UBE2I TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
UBC WRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6603858 18588880
UBE2N UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
EIF3B EIF3H â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
BLM RPA2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
MDC1 LMNA â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
RAD50 ATM â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 18854157
ATM RAD50 â—¼   PHOSPHORYLATION 0.8 0.8 Signor 17570479
ATM CHEK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 10973490
ATM WRN â—¼   PHOSPHORYLATION 0.8 0.8 Signor 10608806
RAD50 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 10426999
MRE11 H2AX â—¼   COLOCALIZATION ✅ 0.81 0.81 mint 22157895 8303386
P53 LMNA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 29568061 30419336 25144556
SUMO2 MDC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 32786267 19471022 22661230 19394292
MDM2 XRCC6 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24147044 24583282 18784078 19247369
SUMO2 RIF1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 29234018 19471022 32786267 21252943 21693764
EIF3B EIF3E â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EIF3G EIF3I â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MDC1 UIMC1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
CP088 NSD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NSD2 LMNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22751105 34079125
H2AX RAD50 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15201865 31501894 16377563 10959836 18583988 19234442
XRCC6 BARD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 15782130
BARD1 AURKB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22350409 19176389
P53 NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28977907 22653443
SSBP XRCC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 24981860
SSBP NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32877691
SSBP HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32877691
SSBP XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 24981860
HERC2 RABE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HERC2 KI20A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25476789 26496610
MA7D2 KI20A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARI3A HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 IF4G1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 21182205
HERC2 IF4G1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
EIF3F IF4G1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19615732 17322308
BRCA1 IF4G1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 23805307
HERC2 ZN622 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29511261 19293945
MA7D2 NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LG3BP NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HSDL2 NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CCD65 NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FA98A NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CC111 NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBXL5 NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEUL4 CE170 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 22261722
CC136 NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BICD2 NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28718761
NEUL4 EIF3C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 29426014
NEUL4 ECI2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 22261722
Z286A NEUL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PRKDC MRE11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10608806 20808282
MRE11 NBN â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
HERC2 FRIL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
HERC2 LG3BP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LG3BP KPBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LG3BP MIO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MA7D2 UBP20 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CC136 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CC136 GRDN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HERC2 RN115 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
MK06 EIF3C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21900206 29426014
MK06 AURKB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26972000 29426014
HERC2 FRIH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
FA98A HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RN166 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CP088 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MA7D2 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MA7D2 UBE3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MA7D2 ECI2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EIF3F TBB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HERC2 TBB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
ESR1 TBB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
CCD65 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CCD65 PCM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
Z286A HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CC111 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CC111 ECI2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HERC2 MIO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
HERC2 KPB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
KPB2 KPBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32296183
FARP2 GRDN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HERC2 GRDN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HERC2 KPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
HERC2 SELO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
HERC2 DNJB5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HERC2 KPBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
APBA2 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB1 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 AURKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 21761334
HERC2 BICD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28718761 25476789
BICD1 BICD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28718761
KAT5 BMI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27295567 16169070
BMI1 LMNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26468281 34316702
BRCA1 EIF3B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 26831064
PCM1 BTF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33644029 26638075
HERC2 COPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
HERC2 COPB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
DISC1 SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17043677 31413325
UBE3A ECI2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22645313 29426014
FBXL5 ECI2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HERC2 ECI2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 22261722
OCRL EIF3C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27173435
HERC2 EIF3F â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 30279242
HERC2 EME1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
KDM4B ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30418174 21502505
ESR1 MARK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
FARP2 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GTSE1 OCRL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25107275 26496610
HSDL2 HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RYBP HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 26186194
SOST HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HERC2 HOOK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HERC2 ZBTB5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
HERC2 LMNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
HERC2 WDR24 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
HERC2 WDR59 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
HERC2 OCRL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
STK11 KDM4A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK2 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
MDC1 MDM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18471438 14578343
SUMO1 MITF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22012259 16189514 16029420 10694430
NPRL2 ZBTB5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PIAS4 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29234018 15383276
RPA1 WDR92 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24981860
SUMO2 WRN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19471022 16524884
EIF3D EIF3H â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
BLM RPA3 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
MDC1 CHEK2 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
ATM MDC1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 12607003
EIF3A EIF3M â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EIF3A EIF3H â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
NSD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24101509 31527615
H2AX LMNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25948554 20000738 23658700
H2AX XRCC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20085707 21679440 18406329
BARD1 MDC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12611903 29656893
CE170 KIFC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 26186194 26496610
XRCC6 P53 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11751391 15782130 32807901
LRRK2 P53 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24725412 26384650
BRCA1 DNJA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22990118 25184681 26831064
DNJA1 HERC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HERC2 SSA27 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 22261722
NEUL4 SSA27 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29426014 22261722
HERC2 NEUL4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31665549 29426014 28977907 22261722 30279242 25476789 29511261
SPZ1 NEUL4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
APBB1 NEUL4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 29426014
UBP16 NEUL4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 29426014
NCOA4 FRIL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 25327288
DBNL UBP20 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CC136 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
HERC2 CE170 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 25476789 22261722
AURKA MK06 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26972000 29426014 23443559
HERC2 NUDC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 25476789 31427565
DISC1 GRDN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
BICD1 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
PCM1 BICD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 34133714 26638075 34079125
HERC2 BICD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28718761 25476789
HERC2 BIRC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 26186194 25476789
BMI1 XRCC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 34316702 24457600 20668194
DBNL ECI2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HERC2 EIF3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 30279242 25476789
ESR1 EIF3B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30573685 31527615 19805454
HERC2 EIF3B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 30279242 25476789
HERC2 EIF3C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29426014 30279242 25476789
UBE3A EIF3C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22645313 29426014
HERC2 EIF3D â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29426014 30279242 25476789
HERC2 EIF3E â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 30279242 25476789
ESR1 EIF3F â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30573685 31527615 19805454
HERC2 EIF3G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 30279242 25476789
HERC2 EIF3H â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 30279242 25476789
EIF3I HERC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 30279242 26186194 25476789
HERC2 EIF3K â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 30279242 25476789
HERC2 EIF3L â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29426014 30279242 25476789
HERC2 EIF3M â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 30279242 25476789
RPA2 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 11953755
FBXL5 HERC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 30279242 24778179
SPZ1 HERC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 35140242 26186194
PHKG2 HERC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23455922 29426014 25476789
HERC2 PCM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29426014 25476789 26638075
EIF3D EIF3M â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CHEK2 TP53BP1 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
ATM NBN â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10802669
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HERC2 RPA1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KAT5 MDM2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RPA1 XPA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EIF3H EIF3M â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
BRCA1 UBE2N â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ATR CHEK2 â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10973490
BLM RAD50 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
UBC USP16 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
BLM H2AX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15364958 29523790
BARD1 H2AX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12485996 11927591
P53 AURKB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20959462 29340707
KAT5 APBB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32296183 15044485 15331662 14699153 11441186 33849647 16713569 16223726 25342469 17368826
SUMO2 BLM â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19471022 16524884 16620772 21693764
PRKDC BRCA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25223785 10608806
ESR1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15961505 31527615
LMNA MDC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30179224 30419336 22412018
SUMO1 PIAS4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20016603 15831457 16524884
PIAS4 SUMO2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
EIF3H EIF3L â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HERC2 NCOA4 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
PRIMPOL RPA1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
TP53BP1 UBC â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
BARD1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
EIF3L EIF3M â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
H2AX XRCC6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15613478 33961781 23145133 20224553 28514442 18406329
P53 UBC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17170702 17268548 17290220 18566590 19098711 19619542 19536131 18388957 17139261 17568776 18309296 17159902 19798103
P53 HERC2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31665549 22653443 28977907 27259994 24722987
MK06 CE170 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26972000 29426014 32707033
MK06 ECI2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26972000 29426014 32707033
PHKG2 KPBB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033 26496610
RAD50 BLM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25084169 10783165 29523790
BLM TOP3A â—¼   COLOCALIZATION ✅ 0.85 0.85 mint 20711169 8048867
SUMO2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21147198 20016594 20016603 22689573 21693764
LRRK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
UBC MDM2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18566590 19166840 17290220 19098711
RNF8 NBN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26869104 18001825 23115235
WDR24 NPRL2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23723238 28199315
TOP3A RMI2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 20826342 20711169 26186194 20826341 28514442
SUMO1 WRN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16524884 15355988 19596686
XRCC5 WRN â—¼   PHOSPHORYLATION ✅ 0.85 0.85 mint 10783163 5212534
WRN XRCC5 â—¼   PHOSPHORYLATION ✅ 0.85 0.85 mint 10783163 5212534
TP53 UBE2D1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
WDR24 WDR59 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
EIF3C EIF3M â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
RNF168 UBE2D3 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
EIF3A EIF3L â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
UBE2D3 UBE3A â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
BRCA1 WRN â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
EIF3C EIF3H â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
H2AX NBN â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 6805208 18583988
H2AX PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15613478 26095369 14627815 18406329 22184063 20085707 20356835
NBN H2AX â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 22157895 8303386
H2AX NBN â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 22565321 8391733
BRCA1 ABRAXAS1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 34591612
BRCA1 CLSPN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15096610 22863316 16713569
WDR48 P53 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19615732 32807901
ZRAN1 HERC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19615732 33853758
UBP20 NEUL4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19615732 23486064
ATM PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10464290 10608806
AURKA BRCA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22110403 26831064 14990569
NBN BLM â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10783165 29523790
EIF3G EIF3B â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 24396066
EIF3I ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 10706629
FTH1 NCOA4 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
RNF8 UBE2D3 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
WRN XRCC6 â—¼   PHOSPHORYLATION ✅ 0.86 0.86 mint 10783163 5212534
TP53 WRN â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
EIF3A EIF3C â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ATR TP53BP1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
WRN H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20802463 15733840
ATM H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18344987 26095369 21704408 22451927 11893489 20081839 16858402 9488723 22184063 11571274 21676867 32518374 27918549
P53 KAT5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17189186 23677994 18280244 18485870 33849647 17704809 15310756 16601686
HERC2 CTNA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29426014 25476789 34079125
EIF3H IF4G1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 32269044 24981860
LRRK2 DNJA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19826009 31046837 24725412
UBP16 HERC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 19615732 25305019 28514442 30279242
UBE3A MK06 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26972000 22645313 29426014
TP53BP1 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 16415788 5218238
H4C6 TP53BP1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 16415788 5218238
ATRIP RPA1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CHEK2 TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HERC2 DISC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17043677 31413325 90000000
EIF3F EIF3A â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 24396066
ESR1 UIMC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31527615 17311814
RNF8 HERC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22508508 20023648 22814251 26503038 25305019
SUMO1 MDM2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18583933 20972456 15876874 21316347 11384992 12393906 12297306 12917636 22411991 15876864 17000718
APBB1 KAT5 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
RMI2 TOP3A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ATR TP53 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BLM RMI2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PSMD14 UBE3A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BLM TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EIF3E EIF3H â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATM BRCA1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ATR BRCA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
RNF168 TP53BP1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SUMO1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
EIF3C EIF3L â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
DCLRE1C PRKDC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
EIF3C EIF3D â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ARID3A XPA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
BRCA1 CHEK2 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
BRCA1 RPA1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
HERC2 NEURL4 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
EIF3A EIF3D â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
H2AX MRE11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12419185 15201865 31501894 16377563 22157895 18583988 19234442
RYBP P53 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19098711 34316702
PRKDC P53 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9765199 19918261 10470151 10713094 9363941 9744860 10601022 11551930 11709713 10951572 16713569 8940078 25362358 11751391 12756247 10673501 10747897 9679063 11883897 10608806
AURKB KI20A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15263015 31586073 26766443
NEUL4 MK06 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26972000 29426014 22261722 28514442 23602568 32707033
UBE3A NEUL4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22645313 30257870 29426014
ATM MRE11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10783165 15758953 10608806
MRE11 BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10783165 28506294 29523790
UBP20 HERC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25355518 19615732 29426014 25326330 30279242 25476789
MK06 HERC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26972000 29426014 28514442 30279242 23602568 32707033
NCOA4 FRIH â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28877469 26436293 25327288 28514442
WDR24 MIO â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27173435 28199306 26449471 25263562 23723238 26586190 28199315
PHKG2 KPB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 26496610 28514442 32707033
ATM BLM â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BRCA1 BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25084169 29656893 26831064 10783165
BLM RIF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23509288 20711169
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
UBE3A HERC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22645313 29426014 21493713 30257870 30279242 25476789
XPA HERC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 20304803 23178497
WRN PRKDC â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10608806 11889123
EIF3E EIF3M â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
EIF3A EIF3E â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
ATR ATRIP â—¼   PHOSPHORYLATION ✅ + 0.88 0.88 Signor 15451423
CHEK2 MUS81 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PSMC1 UBE3A â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
BARD1 UBE2D3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
XRCC5 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
EIF3D EIF3L â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
BMI1 UBE2D3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RPA1 XRCC6 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
EIF3D EIF3E â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
BARD1 UBE2D1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
HERC2 UBE3A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MIOS NPRL2 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
NPRL2 WDR59 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
NSD2 MDC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31248990 21293379
BARD1 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26022179 14636569 15782130 21742769
STK11 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16189514 11430832 28205554 28628118 16713569 21317932
SUMO1 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16732283 23150668 15017387 10961991 18583933 21316347 15327968 23825024 17369817 23543742 15931224 16713569 19684601 15144954 11867732 23604351 12917636 17060459 15576338 15242646 19246003 23772552 16189514 20534433 22214662 20972456 10562557 10788439 16122737 20861261 32807901
P53 AURKA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12198151 30013191 23201157 26186194 28514442 14702041 21761334
P53 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17545634 26556313 10766163 16713569 21761334
NEUL4 DBNL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 17353931 29426014 26186194 28514442
MRE11 XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30585729 10508516 26344197
UBP20 APBA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19615732 28514442 32296183 33961781
CE170 DISC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29961565 33961781 17043677 31413325 90000000
PHKG2 KPB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 23455922 32296183 26496610 28514442 32707033
MDC1 ATM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29656893 26734725 12607005 14519663 18006705 28943310
BRCA1 ATRIP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17616665 29656893 24073851
MDC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21622030 17525332 15569676 29656893 12607005 19766185 12611903
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10426999 29656893 10783165 11504724 25659039 25939603 25184681 19244116 18171670 12124328
BRCA1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
DBNL HERC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194 17353931
DISC1 EIF3H â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17043677 31413325 12812986 90000000
MDM2 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897156 17545634 10766163 11178989 16713569 31012223
MAPKAPK5 MAPK6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 21900206 2001699 8089645
UIMC1 MDC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21622030 24240613 21857162 29656893 22990118
UBE2N RNF8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22589545 31048496 20023648 16215985 22814251 23255131 28244869 25909880 19549727 21706008 26285145 18678647 24732096 31792955 27909234 21911360 29523790
UBC UBE2D3 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
ATM CHEK2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PRKDC RPA2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MIOS WDR59 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MDC1 RAD50 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
BRCA1 UBE2D1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MDC1 H2AX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21622030 21293379 15201865 20159462 18001825 28242625 26734725 16377563 12607005 18001824 14519663 30598506 18583988 32518374 12475977 21676867 19234442 29499138
NBN H2AX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16932743 12419185 11110662 15201865 18001825 31501894 20081839 23145133 16377563 18001824 22157895 18583988 22941933 21676867 15733840
H2AX BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18344987 12419185 26095369 20681793 19805520 18001825 31501894 26121674 10959836 12485996 18001824 19766185 11927591 34321665 29499138
UBE2N H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17709392 18077395
RPA3 BARD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 BARD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 BARD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
ESR1 BARD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17275994
ATM P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23890999 9765199 16858402 15713674 23525106 25086746 10713094 11875057 30252118 15790808 10864201 11551930 17157788 10744722 28654064 11709713 16713569 11459832 20010693 19965871 9843217 17409407 14744854 24469230 15064416 10673501 23907539 21383020 10608806 15159397 27559048 15632067
UBE3A P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 1661671 31492752 16493710 12620801 31971989 17131388 23040663 19364824 29426014 29263404 16713569 7724550 7708685 11027293 16189514 8380895 9369221 9688277 9143503 8090726 26789255 15001357 9450543
BLM P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15806145 11781842 12606585 22653443 15364958 12080066 24239288 16713569 32807901 11399766
ATR P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20798688 10435622 10673501 16293623 10747897 15775976 9765199 11883897 11551930 15159397 10608806 11709713 10951572 11459832 15082766
WRN P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11427532 15735006 12080066 16713569 11399766
P53 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14978302 9582019 14710355 21742769 18501503 9482880 14636569 9926942 16677609 26140185 19509300 15571721 16713569 16969499 31073355
RPA2 MRE11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 MRE11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
MDC1 MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12607003 30179224 29656893 20081839 12607005 14519663 18583988
RPA1 MRE11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
BRCA1 MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10426999 11353843 17349954 23530059 24413181 16391231 29656893 11504724 25184681 10783165
NBN MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12750284 12419185 24413181 21884979 24981860 22939629 12679336 10426999 28369484 17526493 9705271 26455393 12607003 17612497 12447395 22464731 22078559 22231403 34348893 28363998 11062235 15758953 11238951 23530059 33558481 15734743 34038735 30179224 12861053 18458108 19270065 17500065 10783165 30440001 22941933 19244116
MAPK6 APBA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RPA3 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
KAT5 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16141325
ATRIP ATR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17686975 14657349 15210935 17384638 20616048 17526493 18162465 21285353 26854234 19097996 18283122 15743907 15451423 14724280 15538388 28514442 23144622 15758953 19889979 18344416 20847938 11721054
ATR UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18519686
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CDC14B MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20236090
TP53 EIF3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
EIF3C MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EIF3L EIF3D â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22190034 24981860 26344197 22939629 18599441 22863883 28514442 11590142 23623729
EIF3L EIF3E â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 26344197 16189514 22939629 19748344 18599441 22863883 28514442 11590142 17403899 23623729
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
HERC2 XPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20304803
RPA1 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
MDM2 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11927554 16904321
RPL13 MAPKAPK5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RNF8 MDC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24240613 25512560 18001825 26734725 18001824 18006705 28943310
TSG101 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11172000 17060450
PRKDC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17570479 22444248 10721693
NBN RPA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
NBN RPA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
PIAS4 RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20016603
XRCC5 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26496610 22404984 15520013 21679440 26446488 26344197 17308091 15941674 28154079 16857680 20711232 19303849 20023628 15758953 20085707 10750018 10446239 33005030 9312071 28345663 12393188
XRCC6 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8422676 20711232 19303849 26175416 28345663 30585729 17308091 22939629 26496610 10750018 15941674 33005030 21969602 15520013 10064605 21575865 26446488
RPA1 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RB1CC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16061648 21775823
RPA1 RMI2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 RMI2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 RMI2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
SIRT1 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18203716 20428248
SIRT1 XPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20670893 30327428
SIRT6 UBE2D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 SUMO2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
TP53 WRN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9774636 11427532
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
EIF3E EIF3L â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
RNF8 UBE2N â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
MAPK6 MAPKAPK5 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
EIF3C EIF3E â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
PSMC1 UBC â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
UBE2D1 UBE3A â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
RPA2 RPA3 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ATR RPA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ATR WRN â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PIAS4 P53 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 15383276 11388671 16713569
EIF3A IF4G1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 16541103 17322308 24981860
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
MUS81 HLA-A â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
WRN XRCC5 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
MIOS WDR24 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ATM NBN â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
BRCA1 UBE2D3 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
MDC1 NBN â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
PHKA2 PHKG2 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
MDM2 UBE2D3 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
TP53 UBE3A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
H2AX KAT5 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 23777805 20224553 18406329
RPA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RPA3 RPA2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24126761
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
MUS81 LMNA â—¼   KO_UP_REGULATES ✅ + 0.92 0.92 PKG 28854368
PIAS4 UBE2I â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
RNF115 UBE2D1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
FTL FTH1 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 8153045 21516116
BLM MUS81 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
BTF3 RPL13 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
NBN RAD50 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
BLM PAXIP1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
RPA1 WRN â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
TOP3A WRN â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
EIF3I IF4G1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 24981860 26186194 16541103 28514442
COPE COPZ1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
PAXIP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
WRN XRCC6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
UBC WDR48 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ATR BLM â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
EIF3B IF4G1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 23023399 9418880 24981860 17322308 27381497 16541103
COPB2 COPA â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9482852 14729954 10921873 26344197 22939629 8940050 8537409 22863883 9751720
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
COPA COPB2 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
BLM TP53BP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
FRIL FRIH â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 25910212 22939629 16169070 21516116 11591653 25416956 31536960 16189514
EIF3K EIF3B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 18628297 24981860 26344197 22939629 18599441
EIF3H EIF3B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 18628297 24981860 26344197 19615732 22939629 18599441 32269044 26186194 28514442
EIF3F EIF3B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 18628297 31527668 26344197 24981860 19615732 22939629 18599441 30573685 24396066 26186194 28514442 19245811
EIF3K EIF3C â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 14519125 33961781 24981860 26344197 22939629 18599441 22863883 23623729
EIF3F EIF3C â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 31527668 24981860 26344197 19615732 22939629 18599441 24396066 26186194 28514442 23623729
EIF3E EIF3D â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 22190034 24981860 26344197 22939629 20890303 18599441 28514442 22863883 17403899 23623729
EIF3F EIF3D â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 22190034 31527668 26344197 24981860 19615732 22939629 26186194 28514442 23623729
EIF3H EIF3D â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 22190034 24981860 26344197 19615732 22939629 32269044 26186194 28514442 22863883 23623729
EIF3F EIF3E â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 31527668 24981860 26344197 19615732 22939629 26186194 28514442 17403899 23623729
EIF3H EIF3E â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 24981860 26344197 19615732 22939629 32269044 26186194 32867821 28514442 22863883 17403899 23623729
EIF3H EIF3F â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 31527668 24981860 26344197 19615732 22939629 19748344 18599441 32269044 26186194 28514442 23623729
EIF3K EIF3G â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 14519125 33961781 24981860 26344197 22939629
EIF3K EIF3H â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 14519125 33961781 24981860 26344197 19615732 22939629 26186194 28514442 23623729
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
SUMO2 UIMC1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MDC1 MAPK6 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
UBC UBE2D1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
COPA COPZ1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
COPB2 COPZ1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
MDM2 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PSMD14 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
H2AX MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6805208 18583988
P53 MDM2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21317885 11839577 23201157 21316347 25312347 22975381 17369817 21084285 30005830 23443559 21465263 10980696 17936559 10488081 16845383 21149449 22366412 23483203 29549180 14741215 26673821 11713288 18665269 15058298 29524278 28514442 22510990 25241761 22525275 19106616 22467867 25954860 10889512 16595680 24998844 15848166 28628118 28362432 17116689 33650658 14499615 24980433 10608892 26876197 17438265 22103682 22374672 16055726 7689721 17363365 19411066 12167711 23318437 18566590 31796886 30244831 12944468 23261415 27215386 27826076 11178989 19223463 17301054 9724739 32894144 21075307 29121928 19305137 17318220 20659896 20080206 7686617 11744695 18467333 23246961 23150668 23776465 16215989 9223638 16331255 31968249 17908790 14702041 15094782 11278372 28605833 31647545 24200963 10601022 21454483 27893708 21088494 32516735 16861890 26238070 20705607 21887275 19303885 25609649 12915590 31406141 27282385 25156994 23671280 15358376 23609977 25168242 19071110 22991965 22653443 22920093 7926727 17470788 26908445 27856536 26475964 19857530 11709713 11714701 30532073 19411846 11094089 20173098 17591690 9582019 12552135 20542919 28205554 14704432 15001357 29876924 25417702 23880345 20124408 19033382 22487680 30598450 33061576 22575647 9131587 17159902 31152661 17297477 9271120 25384516 24659749 21261729 12529318 22411991 14671306 22084066 20395212 21986495 29487367 33355139 23802716 23370271 23946421 22083959 32807901 15154850 29670376 27905468 35140242 25283148 22085928 11562347 10640350 19098711 32901886 21726810 25624478 25637791 21584881 16870621 12690203 12612087 15824742 11572869 25464845 26203195 22157679 30454706 28082682 9809062 17302414 19085961 24567357 25362358 17080083 17426254 15242646 22524527 29295817 16751805 11431470 26882543 30097011 18604177 20591651 22948151 24462112 10827196 20479273 31533005 22389628 21170087 20694676 17666403 11597128 33503543 14596917 18332869 10321734 21857681 16579792 16414131 18264029 21071676 30464405 17989425 20234175 10681559 27308622 19816404 30355102 19805293 9824166 25313037 16173922 24926618 16159876 26540344 18541670 32904724 17616658 12842086 26720344 27129163 22266868 27031960 32528731 22737255 15604276 16432196 19188367 1614537 22914926 24842904 15247280 32097779 23252402 17347673 16964247 17310983 22331460 30584071 22032989 24240685 31652301 10435614 24621507 24361594 15308643 32334023 16547496 20639885 17139261 15933712 21478269 15313915 23402884 21750659 11112690 19255450 22124327 25277184 19234109 21965653 27336364 15122315 22916255 22262183 15295102 31092600 25512388 16713569 26001071 27807478 31940492 20588255 20174603 20570896 20708156 27886165 17056014 19081178 29547122 23572512 16905769 15542844 19941302 10561590 28542145 32066565 16212962 10202144 28549433 10734067 21572037 18172499 9363941 15550400 17380154 10892746 14559824 22227409 18316739 33495326 17234751 15280377 31177307 24127580 19160491 17290220 8875929 12381304 16857591 18813780 10347217 21561866 24413661 31066983 20847049 21098709 25103245 8058315 22807444 30832340 21268072 20962272 26350565 30175854 20591429 22444248 32427887 16023600 24667498 11351297 11285227 11223036 18784078 11384992 10562557 19568783 31138778 21925390 11486026 19597489 9450543 31665549 22318540 27106262 24207125 15950904 18223694 23728348 22474335 34362424 22912717 20047188 14612427 14517261 30679555 18815136 18061646 28394340 34408321 18309296 11046142 15144954 12897156 23776060 15210108 27811966 19357310 22391559 16338390 29899406 34040386 26186194 11284721 15908921 23652204 33765973 31626714 17848574 9529249 25739118 30879903 10766163 15013777 22588298 18981217 29755129 30320499 11070080 22301280 27543608 30948704 19590512 15558054 12867035 24488098 27462439 18485870 17268548 22819825 31591476 23826318 21471462 9278461 16866370 22659184 19166840 20660730 29269425 31239268 32198344 25543083 17875722 10196247 15053879 21084564 16107876 16678796 17098746 19656744 30109812 11925449 17525743 16624812 30455251 19153082 28553961 21132010 26578655 32874188 31903119 29997244 19837670 20837658 26883110 21060154 33961781 33579943 20235143 15064742 26556313 22745160 20657550 20484049 16152627 11697899 18234963 24314634 12208736 30320919 11713287 28223335 30252118 10722742 31594538 19483087 22266850 24643130 20959462 33020477 21988832 12426395 19332559 23169665 12620407 23134341 27249653
EIF3H EIF3C â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 24981860 26344197 19615732 22939629 18599441 32269044 26186194 28514442 22863883 23623729 30021884
NBN MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20224574 7891431
RAD50 NBN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 19197236 22939629 12679336 10426999 26344197 17526493 9705271 12607003 17612497 12447395 22464731 34348893 11062235 15758953 12124328 11238951 26215093 23530059 15734743 16391231 24651726 30179224 17500065 30440001 22941933 10783165
RNF168 UBC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RPA1 TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EIF3I EIF3L â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ATR CHEK2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
BLM RPA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
COPB2 COPE â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPA1 RPA3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UBC UIMC1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EIF3D EIF3L â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
EIF3B EIF3L â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBC UBE2V2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
EIF3G EIF3L â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EIF3C EIF3L â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
MDC1 FTH1 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
RAD50 MRE11 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12750284 24413181 24981860 19197236 22939629 31501894 30733337 10508516 26344197 8756642 28369484 9705271 26455393 12607003 16163361 11504724 34348893 28363998 11062235 26215093 27173435 23530059 33558481 15734743 16391231 24651726 17694070 34038735 17500065 19270065 30179224 10888888 10783165
COPE COPA â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 31712447 9482852 8858162 10921873 26344197 22939629 27684187 16169070 9751720
EIF3B EIF3A â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 14519125 19245811 18628297 24981860 26344197 14688252 8995410 22939629 18599441 30573685 11169732 16541103 9822659 17469741
EIF3G EIF3A â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 14519125 33961781 24981860 26344197 22939629 18599441 24396066 26186194 28514442 9822659 9341143
EIF3L EIF3K â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 28514442 33961781 32296183 24981860 26344197 22939629 19748344 18599441 21516116 25416956 22863883 16189514 23623729
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
TSG101 UBC â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MDM2 UBE2D1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EIF3A EIF3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EIF3E EIF3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EIF3F EIF3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EIF3H EIF3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EIF3L EIF3M â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPA COPB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3B EIF3D â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3B EIF3C â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3C EIF3K â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3C EIF3D â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3C EIF3I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3A EIF3C â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3C EIF3H â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3C EIF3G â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3C EIF3E â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3C EIF3M â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3D EIF3G â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3C EIF3F â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3D EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3E EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3F EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3G EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3H EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3I EIF3M â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3I EIF3K â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3K EIF3L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPA1 RPA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3A EIF3D â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3A EIF3H â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3A EIF3F â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3B EIF3H â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3B EIF3G â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3B EIF3I â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3B EIF3F â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3D EIF3M â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3D EIF3K â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3D EIF3F â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3D EIF3H â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3F EIF3M â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC1 PSMD14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
BARD1 BRCA1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3A EIF3I â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3A EIF3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3A EIF3M â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3A EIF3K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3A EIF3G â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3A EIF3E â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3B EIF3M â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3B EIF3K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3B EIF3E â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3D EIF3E â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3E EIF3K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3E EIF3F â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3E EIF3G â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3E EIF3M â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3E EIF3H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3F EIF3K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3F EIF3H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3F EIF3G â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3G EIF3K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3G EIF3M â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3G EIF3H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3H EIF3M â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3H EIF3K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3K EIF3M â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UBC UBE2N â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
COPA COPE â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NSD2 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
NSD2 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
NSD2 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NSD2 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
NSD2 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
NSD2 XRCC5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H2AX ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
H2AX UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
H2AX ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
H2AX PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H2AX RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
ATR H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 20461094 20976184 20471486 22224778 17303408 28797244 18677104 19622404 15798197 19793801 9488723 20860841 12919958 18158901 20165693 20936109 22002605 26114388 29114052 21283714 22819196 19282663 24893124 17116885 22531632 17582221 30013081 25438756 26019182 17384638 19647519 20205745 23166506 25852739 18471973 27442013 22247744 29584802 20542002 19875294 25249630 20368801 15459660 27332952 27715493 19772495 25247188 17296725 11877377 14643438 24813610 20613862 17102137 20847938 21148072 23443128 27431324 29163782 23754961 17690115 15975956 18663141 21787120 22545090 27077811 19781914 27164092
BRCA1 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18001824 18001825 17145710 12419185
PRKDC H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 107.0 1.0 Omnipath 18454178 9488723 19321613 21930799 19305155 25487737 22819196 20493860 17570479 12607005 16673875 26976643 17723002 21151168 16039583 21514376 26438602 19049966 20368801 23916969 16935931 27919340 17923115 16061642 18438399 20157519 20461094 21690091 24253929 19531483 26960975 25168287 18758438 19268590 27813335 25690891 17210576 26748709 18406329 23972723 17412408 34429760 27551505 12692309 29221122 20703100 16861886 25070753 27332952 33691101 33863809 23653357 21283714 16788066 19781914 20205745 20860841 21389100 16148027 20116089 15610743 20192759 20224553 14627815 24893124 10734083 20488183 23185622 18157161 33945602 30573684 12766154 25699710 18755145 27738310 10477747 34504648 16820894 20356835 19014481 20713529 17525342 23671119 26114388 23355489 28790110 23678292 20118229 23166506 33986864 15604242 16377563 20609246 12907603 26119999 25072018 15289343 23891091 25269479 23620287 33731502 22972376 34282773 26578593
ATM H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 197.0 1.0 Omnipath 27410735 28544233 16426903 28797244 9488723 23847653 30197789 21930799 18158901 21693595 18848500 22819196 15603757 16760673 17570479 24688021 24793032 27458206 16531125 22028490 30154456 19230794 23202908 25852739 19059218 26073471 22247744 28259974 29584802 25691887 19049966 20368801 26700820 29386061 28124509 20613862 27550454 20847938 27388041 27752097 23269287 24480460 22237206 20461094 20971043 26941327 18285803 21690091 15279774 23891287 25847270 24490130 25349305 26906421 20637859 26314960 15286739 27780918 20454618 30013081 28671946 25218945 23742011 26391293 23972723 23382699 26416514 27442013 20703100 24726884 26512707 27332952 29641431 25287622 26295265 14643438 29163809 25264544 19895790 26504743 26113859 27431324 28790385 18413980 21283714 21787120 20205745 19781914 25093845 27135971 23227178 22224778 20923785 20860841 24244154 23386996 30065307 16858402 11879731 28009280 23343929 20192759 22761798 26855420 24378750 20068231 20580718 14504478 24893124 29048667 25661368 26860083 26019182 20488183 28764946 22205726 23977391 18471973 19591958 28239143 20542002 17525332 20495376 18755145 23050241 17782711 11571274 19473884 28431265 25742493 18248856 17690115 20684759 26317467 21727091 24651472 25827888 27164092 28587922 20976184 30723510 20471486 23772364 29794999 11893489 19014481 20165693 26671524 16997395 20936109 26114388 23845989 15138496 22761813 23355489 27455285 28943310 21348461 19647519 23678292 23166506 28099474 29434792 25249630 25269479 27310012 15177039 22559321 26045162 20865059 22972376 21148072 26760771 21188122 22962268 22768044 26711340 20460517 27845910 28855246
RNF8 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19772495 7575488 18590585 17303408 18001824 18678890 18583988 18001825 18678709 12607003 9407949 17660363 18006705 15279786 15459660
RNF168 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19342239 22980979 31533041 18443409
H2AX TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 20075863 18001824 21317870 12447390 17024177 18001825 21566653 12607005 12697768 21623170
H2AX MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21676867 14519663 18001824 21293379 16427009 16377563 18583988 21622030 18001825 12607005 19234442 20159462 15201865
MRE11 H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
NBN H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATM H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
XRCC6 H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H3-4 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
H3-4 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
H3-4 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H3-4 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H3-4 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
H3-4 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RMI2 BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RAD50 BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
WRN BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TOP3A BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 BARD1 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BLM BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BARD1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 BARD1 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
TP53BP1 BARD1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
BARD1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 99.0 1.0 Omnipath 16403807 16391231 28262780 15159397 25652403 26350354 26490435 14647430 11927591 25184681 16713569 11526114 35203293 9738006 12732733 24289923 11573085 18936166 23086937 24085845 12890688 15855157 24695549 19369211 9798686 11257228 11498787 12700228 11925436 10477523 19176389 23680151 25634209 23416467 34726323 29355525 18369654 14636569 11504724 12951069 19117993 20060929 17873885 14638690 18493658 11278247 15184379 22110403 11301010 11773071 12431996 10635334 20029420 9788437 17664283 21901007 25252691 12485996 10026184 12438698 17525341 16489000 8944023 15265711 12419249 20681793 9342365 27239795 20215511 25823446 19916563
ABRAXAS1 RNF168 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
ABRAXAS1 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
UBE2N ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
UBE2V2 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
ATM ABRAXAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17525332 17525340 26778126
ABRAXAS1 PIAS4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
ATM ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
H4C6 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
TP53BP1 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
MRE11 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
HERC2 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
MDC1 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RNF8 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
ABRAXAS1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17643122 19261749 22357538 17525340 19261746 21282113 19261748 25184681 17643121 19305427 23416467
ABRAXAS1 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
NBN ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RPA3 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CLSPN â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP CLSPN â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RPA1 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP CLSPN â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CLSPN â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP CLSPN â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CLSPN â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RPA3 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18309293 24500207 19473886 12766152 18077418
XRCC5 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MRE11 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
MRE11 WRN â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
MRE11 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
MRE11 TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATM MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19709933 26240375 17570479 31353207 10608806
RAD50 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19197236 16163361 10888888 8756642 17713585
MRE11 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 22464731 26455393 12861053 17500065 15734743 12419185 19270065 22078559 19244116 21884979 12679336 11238951 12607003 9705271 17713585 10783165 12447395 10426999 18458108 15758953
XRCC5 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NBN H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
XRCC6 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H4C6 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H4C6 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
H4C6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
H4C6 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H4C6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
KAT5 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12776177 10096020 32814053 24525235 16844118
H4C6 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 23760478 25579814 23377543 25651062 17190600 27153538 18296440 22373579 19218832 16415788
TP53 ARID3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12136662 22172947 18431400 12692263
TP53 ARID3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12136662 15017387 18431400
BLM ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
XRCC6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
WRN ATM â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
BRCA1 ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
XRCC5 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
ATM RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
ATM RAD50 â—¼   PHYSICAL_INTERACTION 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
ATM TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM MDC1 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
ATM RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
WRN ATM â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
ATM MDC1 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM RAD50 â—¼   SHARES_COMPLEX 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
ATM RPA2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM MDM2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM MDC1 â—¼   ENZYMATIC_REACTION ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM SMC3 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM BRCA1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM STK11 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11331603 11571274 11877377 12234250 12607003 15140942 15459660 15964794 16163361 17303408 18001824 18006705 20160076 23030059 23847781 9488723
PPP5C ATM â—¼   REGULATES ✅ 27.0 1.0 ACSN 12086603 12556884 14871926 14988723 15136767 15175241 15459660 15798197 16260606 16332722 16713580 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 18469862 18995830 19151707 19282663 19342888 19622404 19793801 20051983
ATM RAD50 â—¼   REGULATES ✅ 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM MDC1 â—¼   REGULATES ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
AURKB ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22099307 27493659
PAXIP1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15456759 19414588 17690115
PPP5C ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18772547 17376776 17303408 16858402 19151707 14871926 16260606 16332722 12556884 15459660
ATM RIF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18077418 15342490
ATM RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17525332 11359916
ATM RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 29875999 15964794 11877377 17303408 9725899 16163361 14872059 23847781 9139719 10713094 9295339 20860841 16731533 12607003 22977173 7171818 15459660
ATM NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 12433983 12861053 17485521 23146902 10839545 19413330 15302935 27602502 17429352 19523210 24360018 20068231 17507690 17570479 10608806 12598907 18669648 25088203 18003706 11252893 17431132 23097684 10766245 12814430 10802669 21664921 26512707 10839544 11927276 21130714 17525332 12447395 14707289 15733840 15279770 25119968 18644472 28822740
ATM DCLRE1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15723659 25842165 15574327 15456891 16874298 15468306
ATM BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16199871 11146546 25766002 17984114 14643436 20719863 17363339 14729972 18054789 12034743 30496191 16880735 11375976
ATM MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 28193847 21705321 22234877 12607003 12607005 22234878 17525332 18006705
ATM MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 66.0 1.0 Omnipath 14654783 12383858 17936559 20651945 17303408 19816404 10611322 23150762 23277204 23386996 26416444 27258263 23002429 11331603 15865937 21556066 16163361 23708100 17570479 20514355 22264782 27177180 18265945 28690977 23847781 22264786 15140942 15964794 19788416 22624716 25201202 27462439 12607003 28050229 32350255 22649771 27956626 15459660 22976441 25247188 28904407 11877377 21859827 24534650 23405218 29290977 27568562
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 26927092 17303408 15159397 24746700 12024016 10866324 30197789 12919958 11114888 26745677 26383678 34301763 12427729 11313470 16163361 28035057 20068231 25939603 26320175 17570479 19683496 22743550 10608806 23802008 23847781 21203981 15964794 12183412 12607003 17525332 19996295 15459660 11278964 19651622 21706030 11877377 20952512 10373534 19622773 10550055 27170701 15212693 23704879
ATM SMC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 22369641 18442975 15964794 11877377 17303408 16163361 23847781 17570479 12607003 20501661 19906707 17525332 15459660
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATM CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 176.0 1.0 Omnipath 26683224 17303408 28852018 10713094 20080130 27545311 9488723 15342622 23941746 26485758 28937603 15279786 24882580 10744722 15125777 25746763 18583988 28051860 17570479 16531125 21329876 23892398 19607708 16940182 26643553 20396397 28259974 25361978 17660363 15459660 19375317 25247188 16311512 23118481 20498628 22030216 25613496 22420423 9407949 17918214 12493754 20859824 26158765 15700044 27558808 11901158 27602502 20637859 16163361 20599567 23638118 16481012 12242661 23847781 12024051 15140942 11728459 12454775 16936775 25450480 28950914 26295265 20160490 22319212 24349411 18006705 20723763 18678890 12805407 20860841 23386996 24050180 11668173 27271602 29304495 12447382 24798733 9889122 23347679 18794134 21147465 21421565 26516160 17715138 21376743 19440053 12773400 10973490 17174984 26442630 15694385 11877377 29022904 18809224 11850621 18787700 12718885 19481982 22743550 20372057 15212693 16085488 19101576 29555944 25954303 24473398 18087292 16794575 24492479 24244353 19793801 25404613 21102523 29156743 23253087 16997395 7575488 25808488 20647331 18584027 21851590 21315088 23705030 15629715 29741650 21772273 11025670 18590585 26610585 15964794 29434792 20068082 23006513 19881958 19230643 12607003 24769180 25249630 15024084 19772495 25714019 18603484 25173936 23666059 19473886 27568553 22808196
ATM STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 11853558 25329316 12234250 12805220 18971907 20864035 29284117 21191146 17570479 20160076 25488815 25244018
ATM RAD50 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17570479 17081983 15302935
RPA2 ATR â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR ATRIP â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR RPA3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RAD50 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11850621 11877377 12086603 12607003 14988723 15136767 15175241 15459660 15798197 16713580 16805667 17102137 17116885 17296725 17384638 17582221 18087292 18469862 18584027 18677104 18809224 18931676 18995830 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 22751496 23444773 24050180
ATR RAD50 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11850621 11877377 12086603 12607003 14988723 15136767 15175241 15459660 15798197 16713580 16805667 17102137 17116885 17296725 17384638 17582221 18087292 18469862 18584027 18677104 18809224 18931676 18995830 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 22751496 23444773 24050180
ATR ATRIP â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR SMC3 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR CHEK2 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR MDM2 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR BRCA1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR XPA â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
RPA2 ATR â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
BLM ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
RPA2 ATR â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 14654783 17296725 20651945 11877377 19788416 18677104 19282663 15798197 17102137 17116885 17582221 19622404 19793801 17384638 15459660
ATR ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20616048 15451423 19889979 23144622 17686975 18344416
ATR CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 21722802 20859824 26683224 18677104 19622404 15798197 19793801 27545311 23137030 19836377 20647331 20599567 19282663 19658174 17116885 16481012 17582221 11715017 17384638 29741650 12024051 18802408 10973490 9857181 26442630 15459660 17296725 11877377 17102137 12493754
ATR RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 28666352 23684611 19440044 20860841 18289945 24819595 25520194 19843584 10608806 26057167 17035231 24906880 27908669 22977173 25249630 25070753 26271993 23319600 26212458 29875999 24965470 26474068
ATR BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 26927092 17478428 24746700 15159397 17531442 10866324 18677104 19622404 15798197 19793801 20860841 16713569 11114888 23422745 20936109 16322207 19282663 20068231 17116885 17582221 25879655 10608806 17384638 23346553 12773400 12183412 17525332 15459660 11278964 17296725 11877377 17102137 10550055 16522651
ATR TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17145710 22778941 24395704 28468838 12401524 15159397 24877058 15254178 9733515 11483158 15806145 19056039 11875057 15865930 11551930 11883897 19923893 12548019 18697815 29170437 16293623 19010925 11709713 10446957 9363941 21748595 17272272 22797063 12242661 10196661 22084686 10747897 10608806 10673501 12091386 17118344 23892398 9765199 15489221 24037342 15140942 10435622 17241873 10597277 10801407 11711532 17174997 21593792 25201202 9843217 10606744 15024084 15226429 15922368 21415014 21480565 15585169 24947324 9925639 23380594 9733514 11865061 19625493 16390936 10951572 10570149 23311997 12111733 26144601
ATR XPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 19004803 27247238 18677104 19622404 15798197 19793801 23861882 23178497 27827925 18594563 19282663 17116885 17582221 18790090 17384638 20451471 19586908 15459660 16540648 17296725 11877377 24947324 17102137 30327428
ATR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12186630 22592045 22057367 24500207 18077418 16908529 15507430 29309644
ATR NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17715134 15758953 17526493 18077418
RPA3 ATRIP â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 ATRIP â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 ATRIP â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 ATRIP â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 ATRIP â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 ATRIP â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15743907 12791985 16407120 17339343
ATRIP BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24073851 17616665
BRCA1 AURKA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
BRCA1 AURKA â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
AURKA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22864622 22340593 18026198 24775809 14990569
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
AURKB KIF20A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27939310
AURKB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 20959462 27933271 20847049 15469940 32873634 22611192 27496712
AURKB TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28415769
BLM KAT5 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM TOP3A â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12535671 12972610 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18550849 18931676 19217833 19270065 19282663 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM TOP3A â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12535671 12972610 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18550849 18931676 19217833 19270065 19282663 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM WRN â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 22973052 23253856 24089143 24095737
BLM RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12080066 11399766 22653443 24239288 15806145 11781842 16713569 15364958
WRN BMI1 â—¼   UP_REGULATES ✅ + 36.0 1.0 ACSN 11283614 12202749 12545156 15155580 15385537 16449207 17055429 17116323 17550342 17965729 18398454 18524993 18558713 18584027 18809224 19490890 20027199 20064462 20691907 20713526 20818389 21376743 21733352 2191300 21919891 22657828 22743550 23082994 23140366 23161013 23253856 23869868 24036544 24050180 24709898 9618481
BRCA1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 SMC3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11877377 15459660 16697054 17102137 17116885 17296725 17582221 18451105 19158510 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
CHEK2 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11438669 15459660 15810020 15867354 17296736 17464182 17568790 18048416 18566216 18756267 18931676 18971944 19686080 19788416 20019063 20126263
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
BRCA1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20160719 18851829 9000507 21407215
CHEK2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 18566216 15810020 24492479 20860841 16713569 26383678 10724175 12049740 24986639 23388117 14701743 30327455 33397362 22921572 18804494 24348208 20364141 22941656 15459660 17464182 20952512 24069304 15485917 22193408 12111733 27170701
UIMC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17525341 17525342 17525340 17621610
UBE2D3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 11927591 21531767 16713569 21756275 12732733 22863316 17349954 21113135 25355358 21532592 18369654 16818604 20351172 15905410 16628214 19712108 21965653 15886201 15367667 23246971 12438698 17283126
RAD50 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10783165 16260778 16391231 10426999 11504724 25084169 25184681 16713569
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
CDC14B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10644693 16713569
RAD50 CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
MDC1 CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
CHEK2 TP53 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10710310 10673501 10570149 10673500
TP53 CHEK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15326376 19435816 10531348 19395378 15044452
MDC1 CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 12607004 18087292 17303408 20723763 18678890 19793801 9488723 12919958 24050180 15279786 7575488 16163361 18584027 18583988 22743550 16531125 23847781 18590585 15964794 21376743 12551934 12607003 17660363 15459660 19772495 11877377 18809224 11850621 9407949 18006705
PRKDC CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 77.0 1.0 Omnipath 31959038 12607004 22669845 18948271 16794575 24492479 15829965 23684611 12805407 20406977 26929199 21482692 27818175 20660628 33870196 11668173 21731742 33879618 15618221 11901158 24421316 21099343 12386164 15096610 24415760 12447382 12855706 15213307 16150728 20599567 16024600 17570479 12447371 28750002 34244606 33901880 15367709 26505995 16940182 33747205 11025670 12024051 24844881 15668230 10973490 20713355 33961649 19151762 16936775 16798742 12607003 30001349 18644861 25361978 20305300 11390408 20501833 15361851 16982735 23380594 15674326 17237275 20160490 20498628 33851958 15282313 25550082 31609975 15975956 11085506 12493754
NBN CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 18087292 17303408 20723763 18678890 19793801 9488723 11438675 24050180 15279786 7575488 16163361 18584027 18583988 22743550 16531125 23847781 18590585 15140942 15964794 21376743 12773400 10973490 12607003 17660363 15459660 15024084 19772495 11877377 18809224 11850621 9407949 18006705
CHEK2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15862297 10710310
CHEK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 18778462 25545885 16893723 15254178 18833288 23892398 12052256 18319725 25372714 15459660 20514219 25174607 28140789 17339337 22420423 18566216 20950777 20651945 15810020 15700044 22891162 17157788 11551930 18725978 10724175 15467443 23351141 20096447 11063934 11709713 15659650 12242661 10656682 15140942 20041275 11728459 18614044 12781359 22649771 18812180 11173129 10570149 15279785 20081365 20860841 11875057 22778557 19923893 24553354 22797063 26384650 23316480 15489221 19788416 10801407 21187893 9843217 9733514 10710310 24358900 21526939 23843721 29805302 9733515 25404613 12548019 21625617 10673501 11447225 17118344 26610585 19544417 28038466 12810724 25823026 15024084 17464182 15862297 19933256 20526329 12111733 20183804 23144912
XRCC5 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
XRCC6 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
PRKDC DCLRE1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17242184 15723659 11955432 16600297 23163657 22529269 16874298 21641068 19423708 15936993 1660029
EIF3I EIF3A â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 14519125 33961781 24981860 26344197 17353931 22939629 8995409 18599441 26186194 28514442
EME1 MUS81 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
EME1 MUS81 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
FTH1 FTL â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 17603935 26653790 26794443 27048822
FTH1 FTL â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 17603935 26653790 26794443 27048822
TP53 GTSE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12750368 10974554
KDM4A HERC2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19203579 22589545 22980979 18001825 19203578 18001824 18006705
KDM4B HERC2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19203579 22589545 22980979 18001825 19203578 18001824 18006705
HERC2 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
HERC2 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
HERC2 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
HERC2 XRCC5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
HERC2 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
HERC2 RNF168 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20023648
HERC2 RNF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20023648 22508508 25305019 22814251
RIF1 KAT5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC5 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
WRN KAT5 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TOP3A KAT5 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
PAXIP1 KAT5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
KAT5 RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
KAT5 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
KAT5 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16603769 16904321
KDM4A UBE2N â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19203579 22589545 22980979 18001825 19203578 18001824 18006705
KDM4A PIAS4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19203579 22589545 22980979 18001825 19203578 18001824 18006705
KDM4A UBE2V2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19203579 22589545 22980979 18001825 19203578 18001824 18006705
RNF8 KDM4B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19203579 22589545 22980979 18001825 19203578 18001824 18006705
KDM4B PIAS4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19203579 22589545 22980979 18001825 19203578 18001824 18006705
KDM4B UBE2N â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19203579 22589545 22980979 18001825 19203578 18001824 18006705
KDM4B RNF168 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19203579 22589545 22980979 18001825 19203578 18001824 18006705
KDM4B UBE2V2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19203579 22589545 22980979 18001825 19203578 18001824 18006705
MAPKAPK5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 17624785 23685072 26295581 24818748 18568040 17254968
STK11 MARK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 14976552 19369195 28711359 22238344 17573348 17192257
RAD50 MDC1 â—¼   PHYSICAL_INTERACTION 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
XRCC5 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MDC1 RNF8 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 12607003 15279786 15459660 15496928 15549137 15655342 17303408 17660363 18001824 18001825 18006705 18087291 18171670 18212739 18583988 18590585 18678709 18678890 18809224 19217833 19270065 19490890 19772495 20021983 20064462 7575488 9407949
MDC1 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
MDC1 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RAD50 MDC1 â—¼   SHARES_COMPLEX 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
MDC1 RNF8 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12607003 15279786 15459660 15496928 15549137 15655342 17303408 17660363 18001824 18001825 18006705 18087291 18171670 18212739 18583988 18590585 18678709 18678890 18809224 19217833 19270065 19490890 19772495 20021983 20064462 7575488 9407949
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
MDC1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 15201865 20460517 23115235 14519663 18001824 18678890 19804756 18583988 19230643 12607003 12607005 20224574
MDC1 RNF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 24240613 18001824 25512560 18001825 18678647 18082599 18006705
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
UBE2I MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
UBE2I MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10673502 16713569 10694430 16029420
NBN RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
NBN UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
NBN XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NBN TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
SIRT1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17612497
UBE2V2 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RIF1 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RNF8 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
UBE2N PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 PAXIP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 PAXIP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
PAXIP1 PIAS4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
PAXIP1 RNF168 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
TP53BP1 PAXIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19414588 15456759 17690115 14576432 19481982
PAXIP1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14576432 15456759 19481982 19414588
RIF1 PIAS4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
PIAS4 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
PPP5C PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14734805
PRKDC WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29043077 11889123 17570479 20516064 24429382 18157161
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
PRKDC RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 26811421 9139719 9295339 21300785 28046023 27999209 23684611 19704001 24332808 18289945 15703371 21558276 21731742 20016603 19473888 24819595 21175350 8760901 33826602 19843584 32989256 24830725 19808869 20154705 17570479 25733714 33636182 18669648 23677613 21376743 14872059 22057367 24639502 17035231 31527085 30030458 20691907 17928296 21107010 22977173 11731442 15060176 23319600 19772495 19847258 26166705 29875999 28506294 10064605 34385259 16731533 33357448 19346677 16697054 8943020
RIF1 RAD50 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC5 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
TOP3A RAD50 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
XRCC6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
WRN RAD50 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
RAD50 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RAD50 RMI2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
WRN RAD50 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
TP53BP1 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2N RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RNF8 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
UBE2V2 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RIF1 RNF168 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
TP53BP1 RIF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15342490 23333305 29203878
XRCC6 RNF168 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 RNF168 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RNF168 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RNF8 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RNF8 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RNF8 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 18001824 18006705 19203579 19772495
RNF8 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20023648 21911360 22589545 25909880 16215985 24732096 18678647 26285145 23255131 22814251 19549727
RPA2 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
XPA RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12527904 19446504 7665601 8972858 7876167 20304803 7565690 9535929
RPA1 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 14499497 24126761 24332808 10373438 15735006 15965237 26474068 14734561
RPA2 XPA â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 RPA3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 XPA â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 RPA3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
XPA RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12527904 19996105 10982866 8972858 20304803 7876167 11081631 7565690 32296183 20670893 9535929
SIRT1 STK11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15205477 15744310 15989956 18687677 19590512 19960022
SIRT1 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17334224 16189514 15205477
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
STK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20815019 11430832 17108107 16713569
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
WRN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12080066 11399766 15735006 16713569 11427532
UBE2D1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
UBE3A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 23040663 7724550 9450543 16713569 16493710 15001357 17131388 9143503 19364824 31971989 11027293 9688277 9369221 1661671 7708685 12620801 8090726 8380895 26789255
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
TP53 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12080066 11399766 15735006 16713569 11427532
XRCC6 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
TP53BP1 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
UBE2N TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 17349954 17652783 18196958 19203579 19258535 19793861 19793862 19841479 19851286 22771115
TP53BP1 UIMC1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
UBE2I UBE3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15340381 12820959 18997815 15668399 18298802
UBE2I UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19549727 17698038
XRCC5 UBE2N â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 UBE2N â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2N UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
XRCC6 UBE2V2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 UBE2V2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2V2 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
MDC1 NCOA4 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
PRIMPOL KDM4B â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
ATM LMNA â—¼   KO_DOWN_REGULATES ✅ - -1.21 1.2 PKG 28854368
MUS81 LGALS3BP â—¼   KO_UP_REGULATES ✅ + 1.31 1.31 PKG 28854368
MDC1 FTL â—¼   KO_UP_REGULATES ✅ + 1.49 1.49 PKG 28854368
PRKDC ATM â—¼   KO_DOWN_REGULATES ✅ - -1.5 1.49 PKG 28854368
XPA KDM4B â—¼   KO_UP_REGULATES ✅ + 1.79 1.79 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368
PMS1 PMS1 â—¼   KO_DOWN_REGULATES ✅ - -7.89 7.88 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368