Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MEF2D SOST â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17696759
MEF2D MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8798771 9858528
WNT6 LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
AP2A1 SMAD9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
BMPR1A SMAD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19620713 11792802
FOXO1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21149440 23430617
FOXO3 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18268343 0706790105
FOXO3 SIRT1 â—¼   DEACETYLATION ✅ 2.0 0.8 Reactome 14976264 23665396
LRP5 SMAD9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
WNT9A LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
WNT9B LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
WNT10B LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
WNT2 LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
WNT2B LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
WNT7A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12857724 15578921
WNT10B LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
WNT9A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
MEF2A SOST â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17696759
MEF2C RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
MEF2C SOST â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17696759
PRMT6 SMAD9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
LRP6 WNT1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
MEF2B MEF2D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST IMA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST MPPB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST ANM6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST IMDH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST SAHH3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT7A WNT7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST BACD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST GCSP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST CSH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST DCAF5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST GTF2I â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MEF2B MEF2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MEF2A MEF2C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 33961781
MEF2B MEF2C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST PSMG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST PSMG3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST SRRT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST SPOP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT3A WNT3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
WNT4 WNT7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PSMG3 PSMG2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 17189198 26186194 33961781
LRP6 WNT3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
WNT1 LRP6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11448771 11029007
SIR1 FOXO1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18235501 15220471 16154098 15692560 22013015
SOST LRP5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 15908424 21471202
MEF2D MEF2A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 8798771 25609649 9858528 20590529
SIR1 FOXO3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20733005 14976264 21713995 15126506
WNT3A LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25425204 21078818 15578921
FOXO1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21471200 21281751 20650891
SOST LRP4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 21471202
WNT8A LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23209147 15578921 32196115
SOST LRP6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21944579 15908424 28514442 21471202
WNT2 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23209147 15578921 32196115
WNT9B LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20093360
MSX2 WNT7A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15591538 15841209 21514273
SIRT1 FOXO3 â—¼   DEACETYLATION ✅ - 0.9 0.9 Signor 24003218
FOXO3 SIRT1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
LRP6 SOST â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
WNT3A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23400998 21078818 19339249 12897152 14739301 24265322 16890161 22726442 19910923 15578921 20093360 22491013 18772438 21944579
WNT7B LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15578921 15923619
LRP6 WNT8B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
FOXO3 FOXO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19244250 16100571 18202312 23509296 19690465
SIRT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 24003218 22013015 14976264 18235501 15220471 14980222 22395773 15788402 15692560
HIF1A FOXO3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
FOXO3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23525956 20816089 15604409 23262029
SIRT1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 24003218 14976264 14980222 15126506 21713995 15917664
SOST LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22696217 15778503 21944579 15908424
WNT1 LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21078818 11336703 15578921
LRP6 WNT8A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
WNT3 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18528331 15578921
SOST LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22696217 15778503 21944579 15908424
WNT1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21078818 11029007 10557084 23331499 29444668 21071413 11448771 18988627
MSX2 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15383550 11683913 16115867 17060321