Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CTNNB1 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20571031 12200448
SP1 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12888575 18481199
THBS1 CCN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18550634 16878133
ABL1 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 SNX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 LRP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 MEPE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP1 AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12032593
PPARA AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15067378 20613959
RHOA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LRPAP1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DAB2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNX17 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TBP APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MMP2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAC1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CLU APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20573181 7894075
APP PLAU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YBX3 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10692164 12644490
APP DLG4 â—¼   COLOCALIZATION 2.0 0.8 intact 20573181 7894075
OCRL APPL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8184127 21378754
APPL1 LRP2 â—¼   COLOCALIZATION 2.0 0.8 intact 21971085 8306957
LRP2 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PPARA CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DLG4 CLU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CTNNB1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17306568 12782598
DLG4 DLG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
EEA1 LRP2 â—¼   COLOCALIZATION 2.0 0.8 intact 21971085 8306957
VDAC2 LRP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PPIB LRP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
M6PR LRP2 â—¼   COLOCALIZATION 2.0 0.8 intact 21971085 8306957
LRP2 OCRL â—¼   COLOCALIZATION 2.0 0.8 intact 21971085 8306957
THBS1 MMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10900205
RAC1 OCRL â—¼   COLOCALIZATION 2.0 0.8 intact 12915445 8276229
SP1 PDGFD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189269 18258854
ZN408 LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN264 LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZSC29 LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MANS1 SNX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MANS1 LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MANS1 APOE â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
F19A3 LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
F19A3 INSR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN224 LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TAP26 LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHG19 LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AMBN LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CTGF LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
INSL6 LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RIBC2 LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VIP LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PDGFD LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MEPE LRP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APP DAB1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
ZFP41 LRP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CTNNB1 PPARG â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MAPK8IP1 MAPK8IP2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
LRP2 VTDB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11717447 16713569
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
LRP2 UROK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8344937 16713569
LRP2 LIPL â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 7686151 16713569
RET1 LRP2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10203351 16713569
LRP2 APOA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10073957 16713569
LRP2 UTER â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11278724 16713569
RBP1 RAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 7673236 16189514 32203420
LRP2 APOE â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 7768901 11421580 16713569
LRP2 APOH â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9727058 16713569
LRP2 CLUS â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 7768901 9228033 16713569 17260971
ITBP1 LRP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16713569 10827173
LR2BP LRP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12508107 16713569
APP CLU â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ATN1 MAGI1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9647693 16713569
MAGI1 LRP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16713569 11274227
APOE APP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
JIP1 LRP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12508107 16713569 10827173
JIP2 LRP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12508107 16713569 10827173
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
ARH LRP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14528014 16713569
ANRA2 LRP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22649097 11095640
DAB2 LRP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16713569 10769163
LRP2 AMRP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 7512726 16101684 11912251 16713569 28514442
TBP APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8015372
RHOA DLG4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9870943 9870942 16202622
RAC1 DLG4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9870943 9870942 16202622
DLG4 LRP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12713445 16713569 10827173
MAPK8IP2 MAPK8IP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10629060 10490659
TIMP2 MMP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9933646 9410885 9182583 12374789 28514442 12032297 10991943
APP MAPK8IP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ZBTB48 ZNF408 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
APBA2 APP â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
DLG2 DLG4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 21653829 9182804
LDLRAP1 LRP2 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
DLG4 DLG3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10026200 28973854
JIP1 JIP2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 28514442 10629060 10490659
MMP2 TIMP2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
PPARG CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19466435 16306131 16723090 31023188 18274641 19902320 11590167 18991162
ABL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16099633 25164010 17618275 24465953 20841568 17318191 20840866
ABL1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30323259 25368164 26385316
ABL1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11279131 20841568
AGT LRP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15467006
APP APBA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12196555 12972431 11517249 9890987
SP1 APOE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15670754 11229886 18467438 2188976
APOE APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9202294 10559559 10428074 10842709 17116874
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372
CLU LRP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 32332780 17260971 7768901 16713569
PPARG CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12021175 15190077 20303941 14764597 19075513
RAC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19751508 28626389 26403202 19417647 22270359 16212495 16940750 12480336 11152757 29497040 30650643 19020303 15377999
CTNNB1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25721714 16847334 25168821 19495794
SP1 GC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24382322 17312152 23137637 9493965 9632663 19244234 12052832
SP1 INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 1311316 18310298 7776968 15131018 12706836 12665574 7983788 16707431 22033326
LRP2 LDLRAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 14528014 23836931 7768901 8710919 8706697
TCN2 LDLRAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 14528014 23836931 7768901 8710919 8706697
PPARA LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10774955 15713663 12208475 10634806 8895578 12042669 9226459 14960661 16890192
PPARG LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17658475 10098492 8895578 18948972
PPARA LPL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20813756 18391971
TCN2 LRP2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 14528014 23836931 7768901 8710919 8706697
PPARG MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17908458 17625041 16609149 15838654 19345798 17425848
SP1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 16453304 19061309 19853299 16575904 21045016 10506168 21520171 21469139 15317818 17258390 19126647
TIMP2 MMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 9182583 19010413 12023034 9410885 12475252 21839835 9933646 12032297 12374789 10991943
SP1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23978400 10361124 21567400 21076612
PPARA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12941763 16226723 20706641 17261671 18769491
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
SP1 TIMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15691353 16275157 10764764
SP1 TCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9632663 9774437