NOS3
|
ACTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
CDKN1A
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19541625
0812254106
|
AHR
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12203118
24431146
|
CDKN1A
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16616141
5218511
|
DDB2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16678110
|
TGFB1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23741479
12058028
|
AHR
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17070097
15111621
|
ESR1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24559156
10851069
|
ETS2
|
CDKN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11234019
|
ETS1
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16564026
|
SMAD7
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15788410
11279127
|
SP1
|
COL1A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19558215
|
TP53
|
DDB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11971958
|
SHC3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
EGFR
|
H3C2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
MMP2
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15313914
|
TP53
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
HIF1A
|
LRP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19828020
21454812
|
LRP1
|
FZD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14739301
|
F2R
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
MAPK1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ESR1
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23250869
22430216
|
MAPK1
|
MAP2K1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
23241949
8412360
|
MAPK1
|
PPP2R5C
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
16456541
5218298
|
FGF2
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9490736
12750158
|
HGF
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16397249
17667909
|
RUNX2
|
PPM1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1107017108
22065775
|
PPM1D
|
RUNX2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22544321
22065775
|
RUNX2
|
PPM1D
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
1107017108
22065775
|
TP53
|
PPP2R5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219546
17245430
|
PPP2R5C
|
ATF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20730097
|
TFRC
|
TF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20404192
0914898107
|
TF
|
IGFBP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11297622
11749962
|
ETS2
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8649821
10510472
|
TP53
|
MFGE8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17637751
15340061
|
TP53
|
H3C2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16980608
|
TP53
|
HLA-E
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1400626
1652755
|
TP53
|
COL18A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15958553
|
TP53
|
MAP2K1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10529175
9724739
|
TP53
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17564708
24180280
|
TP53
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15230856
8732672
|
TP53
|
STEAP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
19302216
|
TP53
|
GSK3B
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5216887
14744935
|
TP53
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
SERPINE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10766163
16713569
|
TP53
|
STEAP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
MMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
HGF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
COL18A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
HIF1A
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17504662
15723200
|
ETS1
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22266280
17376198
|
ATF1
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10540320
|
SP1
|
IL10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18843277
|
ATF1
|
IL10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20154735
|
SMAD1
|
GADD45G
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22219353
|
RUNX2
|
AXIN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19585539
23300083
|
ITGB3
|
ITGAV
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214491
11546839
|
ITGB1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ITGB1
|
CCNE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
FN1
|
ITGB1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21985969
8208414
|
VTN
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7716514
32196115
|
FYB1
|
SKAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
18760924
20164171
|
FYB1
|
SKAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
18760924
20164171
|
SMAD7
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10519551
19758997
|
SMAD7
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15632190
14761601
|
SMAD7
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15684397
1568439
|
SMAD7
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19397700
12207925
|
SMAD7
|
SERPINE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18762808
17438144
|
AXIN1
|
SMAD7
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16601693
5218493
|
TGFB1
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21358634
9679059
|
SMAD2
|
TGM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMAD2
|
RUNX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15599395
9812998
|
SMAD2
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17058229
12411395
|
SMAD2
|
GADD45B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14630914
12933797
|
SMAD2
|
NANOG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21402155
|
AHR
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19461128
16289099
|
NR4A2
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18550828
19721341
|
ETS2
|
MMP9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19847259
23977064
|
ESR1
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10935492
12878732
|
RUNX3
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21128246
|
RUNX2
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19915614
16166639
|
AHR
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19371443
19755661
|
MMP9
|
FBN2
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
10229672
10386589
|
THBS1
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11606713
10900205
|
TGFB1
|
VTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11796824
16189514
|
TGFB1
|
COL2A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16189514
10085302
|
THBS1
|
ITGA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11980922
10982388
|
ITGA4
|
ITGB7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12626562
19454690
|
ITGA4
|
ITGB7
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12626562
19454690
|
GSK3B
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219694
17318191
|
APP
|
NGF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NGF
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CASP8
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RUNX3
|
CASP8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15930301
|
CASP8
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10409650
10911620
|
CASP8
|
PAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16186808
|
F2RL1
|
HLA-E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
THBS1
|
ITGA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11980922
10982388
|
THBS1
|
MMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10900205
|
ITGA5
|
FN1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16457822
5218313
|
RHOA
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HIF1A
|
HDAC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19071119
6802010
|
HIF1A
|
ITGB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19828020
23640055
|
HIF1A
|
FLT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16601206
15192019
|
HIF1A
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19934262
15780936
|
ATF1
|
FLT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7499271
|
M6PR
|
LRP2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21971085
8306957
|
VTN
|
SERPINE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216470
12808446
|
ESR1
|
SERPINE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15217907
|
ETS1
|
SERPINE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23708702
11590145
|
ELANE
|
SERPINE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7521069
16713569
|
SERPINE1
|
ELANE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
7521069
16713569
|
SERPINE1
|
PLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11113116
16713569
|
PLG
|
PLAT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2318848
7199524
|
PLG
|
PLAT
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
2496749
2962641
|
PLAT
|
PLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11928826
1447176
|
SP1
|
ETS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20045441
12560478
|
ETS2
|
VWF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9444957
|
ETS2
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9334186
16189514
|
NOS3
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17502619
0611416104
|
CAV1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DROSHA
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5212972
10976766
|
SP1
|
FOSL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16288017
13679379
|
SP1
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11133225
7499419
|
SP1
|
ETS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12706891
8247540
|
SP1
|
F2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12911579
|
SP1
|
MAP2K1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17889508
16452190
|
SP1
|
COL18A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11093745
|
SP1
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15158147
19302822
|
SP1
|
ADAM17
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19772640
|
ETS1
|
TFRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12439744
12547252
|
ETS1
|
TIMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10051488
8557686
|
ETS1
|
ITGB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11556732
|
ETS1
|
ITGA10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16684505
17726260
|
ESR1
|
ITGA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18414489
|
VTN
|
FBN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
FGF2
|
FGF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18552176
18757403
|
FOSL1
|
ITGB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23319049
|
SMAD1
|
NOTCH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMAD1
|
RUNX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19664780
24692107
|
SMAD1
|
RUNX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17215250
22298955
|
MYL9
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
10639334
10047984
|
TUBA1A
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HDAC5
|
RUNX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22298955
16613856
|
NR4A2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SHC3
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DVL3
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
COL4A6
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MMP2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
PLSCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
F2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GSK3B
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219694
17318191
|
GSK3B
|
FOSL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20154735
|
CTNNB1
|
TBPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
32448362
25921273
|
CTNNB1
|
AHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19651607
0902132106
|
CTNNB1
|
NANOG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
32448362
25921273
|
ESR1
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16628468
|
CTNNB1
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17306568
12782598
|
CTNNB1
|
NR4A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
21362399
|
NOS3
|
HTRA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
ESR1
|
NOS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17921256
0704315104
|
ESR1
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18313050
19861308
|
ESR1
|
TGFB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12580758
11159847
|
PAX5
|
CSF1R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21549805
16482219
|
PAX5
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15676205
|
TBPL2
|
NANOG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
32448362
25921273
|
LAMA2
|
ITGB4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7721947
32196115
|
MMP2
|
FBN2
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
10229672
10386589
|
MMP16
|
MMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23691193
24376839
|
ELANE
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10978167
|
ELANE
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10978167
|
RUNX2
|
COL2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11331591
16029574
|
SDC2
|
SDC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18093920
0708909105
|
SDC3
|
SDC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18093920
0708909105
|
VWF
|
GP1BB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1939645
2010539
|
EGFR
|
TUBA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
CAV2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
TGFB1
|
MMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
16189514
25241761
10652271
|
CAV1
|
RHOA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
31871319
20460433
9647788
|
GSK3B
|
SMAD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
25241761
18045539
|
ITGA2
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
ITGA5
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
VCAM1
|
ACTN4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
EGFR
|
PSMD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20029029
31980649
|
EGFR
|
IGF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17047074
17307140
|
AXIN1
|
AXIN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22682247
20128690
|
HIF1A
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
CAV3
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
VCAM1
|
FSCN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
FGF8
|
DDX31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ESR1
|
PGR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
825.0
|
0.82
|
STRING
|
36370105
|
IFNA5
|
IFNA6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AXIN1
|
DVL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22682247
12805222
20128690
|
ARHGAP5
|
RHOA
|
â—¼ GTPASE_REACTION
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
32203420
|
AXIN2
|
CTNNB1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
11940574
|
AXIN1
|
DVL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
834.0
|
0.83
|
STRING
|
36370105
|
ESR1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ITGB6
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CAV1
|
NOS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CALM2
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
ESR1
|
IGF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10749889
24051437
14764897
28555617
16113100
|
RUNX2
|
SMAD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10531362
10962029
17215250
20851880
|
HDAC5
|
RUNX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24229708
15138260
|
CALM2
|
NOS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
GSK3B
|
CTNNB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
16293724
|
ITGA4
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
ITGAV
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
ACTN4
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
21078666
19805454
25604459
|
SMAD2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
20207742
11555647
|
ETS2
|
ETS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16189514
9334186
|
FGF2
|
SDC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16982797
8344959
|
FN1
|
TGM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
RUNX2
|
SMAD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
ETS1
|
PAX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
COL3A1
|
PCOLCE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
SMAD7
|
AXIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16601693
18593713
|
ATF1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31527615
21217774
|
GSK3B
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
MMP9
|
TIMP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
24330623
33961781
|
ESR1
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10681512
17656465
17312152
16651265
18765668
10446910
15084343
16439465
15637147
19652226
15705965
15987735
9611253
15557281
9328340
|
RYBP
|
E2F2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16189514
12411495
|
HIF1A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
FN1
|
ITGA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
AHR
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
MAPK1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
FN1
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
SMAD2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16713569
28065597
20935677
11887937
17284441
|
AXIN2
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12183362
10966653
33961781
23602568
32707033
23455922
29568061
30824926
|
SMAD2
|
SMAD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9111321
28628118
18729074
28205554
|
SMAD2
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11114293
10878024
22227581
|
CAV1
|
NOS3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
8910295
12852865
11425855
17502619
|
FGF2
|
SDC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
16982797
33961781
|
CAV1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
ITGA1
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
LLGL2
|
PARD6G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
ACTN4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
26320552
|
SHC3
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22973453
9685397
8610109
16273093
8662772
9507002
|
EGFR
|
LRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
28065597
|
HIF1A
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12228247
17024177
17418410
15780936
|
AHR
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15837795
19460354
12612060
27420286
17392787
10620335
9611253
|
LRRC32
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
CDKN2A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
CAV1
|
CAV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
TUBA1A
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ATP6V1A
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDKN1A
|
COL4A5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDKN1A
|
GNB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SMAD1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19819988
11786386
|
ETS1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18955504
12740370
|
CREB3
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19340300
|
EGFR
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18955552
20937854
15156151
|
EGFR
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20624308
24189400
21918175
24362532
10722725
23866081
26551075
|
EGFR
|
CAV2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
24658140
15273741
25402006
16799092
|
EGFR
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16407214
19446582
22411794
31980649
12388423
24658140
15273741
25402006
16799092
9374534
34079125
12354760
10781609
15657067
|
MAPK1
|
MAP2K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
RHOA
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10617617
9854026
12810709
|
MAPK1
|
BMF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22258404
|
ESR1
|
TF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12459033
|
PAX5
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8521821
22105368
21319196
|
TP53
|
COL2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17003465
24192518
16917063
|
TP53
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8090761
10029407
|
TP53
|
NANOG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18371449
20631301
15619621
|
TP53
|
HGF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17216187
18431400
9023107
|
TP53
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15469934
14586398
|
PPP1CB
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19036824
|
AHR
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20676095
20676092
24315995
|
SMAD1
|
ID3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18372118
21056086
|
MET
|
HGF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17804794
18593464
15167892
1846706
28628118
1655405
19433454
20624990
18495663
16537482
22897854
28205554
17981115
8380735
|
CHAD
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9281592
|
COL4A1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8223488
|
LAMA2
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11278916
|
SP1
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16714330
10843994
|
AXIN1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16601693
|
SMAD2
|
TBPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
21245162
32448362
25921273
|
SMAD2
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19397700
17481939
15954899
|
SMAD2
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
27974707
11456453
16284942
|
SMAD2
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18729074
9111321
|
RUNX3
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20574006
17195845
19139168
|
ATF1
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18641343
12836278
9834094
|
ETS2
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19411629
12438253
|
HIF1A
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20631454
19285046
19950212
|
TIMP1
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24330623
19010413
|
MMP9
|
TIMP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24330623
19010413
|
TGFB1
|
BGN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10383378
16189514
8093006
|
FN1
|
ITGA4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
20644254
22067905
24202395
|
ESR1
|
ITGB7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
AXIN1
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
17601533
21988832
10228155
24976009
30181396
20128690
12511557
17318191
16293724
23455922
28546513
17318175
19303846
18632848
19131971
16890161
26496610
23892894
23602568
22613765
18593713
29568061
21242974
22682247
19759537
11738041
22270359
24451375
9734785
32707033
21502811
17510365
10481074
16199882
26912724
23959799
29045831
22509369
29789528
19202075
12584189
|
CUX1
|
NGF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
7556925
12619038
10900073
|
SP1
|
NGF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22609358
16135093
21123453
|
THBS1
|
PLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
6438154
2522013
|
THBS1
|
TGFB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22943793
8349738
21900405
|
ADAM17
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14970227
|
HIF1A
|
TIMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10334664
15048879
|
HIF1A
|
TGFB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10831118
16611863
|
ETS1
|
FLT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16861237
18625704
10554042
|
SERPINE1
|
PLG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
11021826
20027185
25502501
|
KLF2
|
SERPINE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15718498
17194892
23723375
|
PGR
|
ETS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
ETS2
|
CSF1R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8552081
8981363
9506963
|
CAV2
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12414992
16189514
31980649
9361015
18081315
33961781
24013648
10212252
|
CAV1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11563984
23634843
22230296
19595769
|
ESR1
|
CAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12138116
18414489
|
SP1
|
F2R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9494121
12975361
|
SP1
|
ADAM17
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19772640
22705645
|
SP1
|
COL5A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7646438
|
SP1
|
COL7A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10980546
9092567
|
SP1
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7541039
|
ETS1
|
VWF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9444957
|
ETS1
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11857377
18181172
8934537
|
COL2A1
|
ITGA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7688313
|
CHAD
|
ITGA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9281592
|
COL4A1
|
ITGA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8223488
|
VWF
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16040750
14754902
10446041
|
ADAM17
|
NOTCH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19601831
19726682
19704010
|
ADAM17
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9774383
12535668
|
FN1
|
ITGA3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9733622
|
FN1
|
ITGB8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7542940
|
ITGA3
|
LAMB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11964076
16413178
16581764
|
TUBA1A
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CUX1
|
KIF23
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19015243
|
CTNNB1
|
RUNX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16575901
16043491
24692107
|
DVL3
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10644691
10806215
|
RBM39
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21182205
33731348
11704680
15694343
|
RUNX2
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17350616
|
ESR1
|
PRLR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16705189
16651265
18414489
|
ESR1
|
NOTCH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19376833
|
FOSL1
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20353950
19289495
18288638
|
F2
|
F2RL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
873923
8615752
10079109
|
LAMB3
|
ITGB4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12867433
8143784
32196115
|
COL4A1
|
ITGB8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7542940
|
VWF
|
ITGA2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16040750
14754902
10446041
|
TGM2
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16407273
|
LAMA2
|
ITGA7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11278916
|
ESR1
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
EGFR
|
SHC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
AXIN2
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
F2
|
F2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
FN1
|
ITGAV
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
PLAT
|
SERPINE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
CTNNB1
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
5219694
17318191
|
ATP6V1A
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
SP1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
CCNE2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
F2
|
FGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
ITGAV
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
CDKN1A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
SERPINE1
|
VTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
AXIN2
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
CTNNB1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
MAP2K1
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
TF
|
TFRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
FN1
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
ITGA5
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
ITGA2B
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
AXIN1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
AXIN1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
TP53
|
CCNG1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
7957050
18431400
10094833
19925028
9688532
14581561
16540664
12642871
9233778
9525742
|
TP53
|
CCNG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12556559
16713569
12642871
|
TP53
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
389.0
|
1.0
|
Omnipath
|
9349504
22270849
8749722
21242964
22290440
23874636
23349794
23650552
17280505
16288208
19882681
22948151
8641969
18840648
7777546
9360984
9707425
14614448
15586362
12889596
10597242
18719376
17938176
16343438
9916993
12806965
15024021
10037739
19394332
19749793
22480684
15136035
19501055
22732402
15988033
17307334
18272192
23665236
20331637
10435630
12239594
14743206
24599959
9714336
9652736
19954840
12392301
15339933
9154806
19383287
21295542
16894028
23187802
15248906
14522900
18483411
16261158
11892838
20190809
17167174
18615633
15790310
17916908
19472317
12717415
19789303
16317118
7696178
24584189
22989750
18573881
22532570
9288775
16103882
11890931
17646389
17344317
10753197
8557703
15872011
24356969
11278953
22279545
12902982
9920903
18644983
21524151
16540664
10935506
16537920
19843844
9535786
17878219
9405685
10749849
18656471
11021966
19723072
16778363
18628250
16557594
9614553
21791610
10072388
12203124
12420214
12640112
16601686
20531308
15741235
17317670
18446786
18505818
9224526
17569660
21900401
14517211
12934105
22713239
11313928
15492238
17509529
15985438
14722112
18755897
15489892
23759594
7624148
17786325
9223430
24074410
9525742
11395510
21317932
11444825
18645021
15856024
10559267
18593586
16970927
12665570
10101800
23017582
20696891
9268733
22001409
24821728
23146670
22427654
12573582
19118657
11973611
24096481
20797428
17685229
23066038
10029406
12681065
12433990
18769160
15208672
11152513
8547219
15851483
23474493
24384472
11175333
17158927
23100276
17762884
18951877
12045203
15051477
16107883
18521083
23159636
8603071
20814747
15082782
11375890
21084835
10348346
22244155
21325288
12379483
14580351
17592775
8910340
15566940
12173040
12007564
12609999
8878553
12080472
12384701
22266868
17404570
23329847
7478511
15067082
15007388
16458891
9268365
15728246
17224908
10094833
15897882
18059034
11739748
7624134
17146435
18690848
21528307
21546904
18208621
18172861
17977830
17721438
20817677
22894933
18225552
21642427
11162600
9183012
8647846
10660101
21858218
22514644
18451802
11384995
20673369
7774811
20187950
16230382
17339230
12168779
19630958
8242752
9895308
21606339
11748232
16410722
22611192
16061648
15009091
22503977
8799837
15660129
20473858
20448457
16488074
14612423
21903579
11668476
11313463
17101782
19067706
17121856
10792001
16341121
12925527
7566157
22190353
12782287
9233781
15509808
21245169
17145718
24134839
10498892
18094076
14635196
23208500
20843368
10327058
21969549
9440695
10625687
20885946
12851404
19846554
10910098
14614455
18419600
21552844
24835508
21541551
9472102
11922774
19244234
17903248
9216067
18193090
10566557
18757425
11429705
19608464
8632901
8691637
15184659
12716906
15259070
24559687
7970699
15738655
9588214
16574813
15302882
12560513
16131836
16778203
10522058
11032828
9816111
9108440
15860260
17108107
25024194
9582019
22266186
20036872
9926942
15710329
19243472
17997002
19435914
21093383
23149933
11162506
17678435
11895854
8616838
12748190
17610896
18269916
22086179
21557991
17942917
24821727
11557753
16204065
18645003
24205274
9816061
12226108
24379401
15539944
7753560
15371422
10799578
10777217
16434701
17996705
21957244
9191059
9519881
9207798
24289924
21733196
15496412
20124454
20153576
22172947
10321740
21715977
22253232
8816885
24189165
15882981
8752276
20511722
11514734
20962589
12869419
16733561
19713748
16931520
10499591
16581545
19738071
|
SMAD2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9618481
12200968
17516505
14762439
10506225
24052079
14583455
|
RUNX2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21913213
17438369
19179305
15107836
12391164
|
SMAD7
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10878024
15922743
20104486
12185267
15555279
11180003
|
HIF1A
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15071503
15190211
10559391
20043814
21362093
|
ID3
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23342268
22564737
17639499
20191379
|
ESR1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15557281
16628468
20696891
16847062
12151347
11517191
15378598
11274368
16469747
17681750
20301197
22787161
23349794
|
CUX1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11584018
12438259
15812824
15269344
|
SP1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
101.0
|
1.0
|
Omnipath
|
9580699
15978937
15557281
11064455
16103879
19584258
20301197
20935676
15961274
15361832
11274368
11842244
15489892
15302882
10212208
12796485
23184467
14529564
12806965
9819384
10321829
10649433
12434298
18270969
18850004
16081043
9183012
21858218
10809237
9618481
16298343
11574165
10362258
11384995
15659839
14744793
10030670
17090534
10733944
19318349
12665570
18202149
17516505
15033443
22001409
17885207
10485470
9553133
15345676
15694838
22427654
17556661
10506225
23066038
15979845
18636159
14527674
24821727
15899840
14755691
12151347
24589735
18210215
23877711
11953011
21311948
15528212
15790310
10878024
22132221
12782287
12773551
8995437
21184768
12379120
17026958
24451377
10601254
8557703
16810128
16533812
7499379
10625687
15389873
16706751
12727210
21325288
16818630
18419600
15041706
23235480
19244234
15694666
23329847
18509005
|
TP53
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
19922265
12897156
19597488
16616141
28433629
20066118
20457558
19749794
6396087
21163364
17371838
21900206
21340684
25241761
12897801
12748190
20182602
11896572
|
MAPK1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20519948
19364816
28368408
|
SMAD2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9389648
9618481
12545156
17550342
11013220
15155580
9670020
11074002
11283614
|
GSK3B
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
22154077
28916781
12058028
11779850
17570479
20519948
15212693
17283049
19440234
|
SP1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17026958
9389648
9618481
17550342
12545156
11013220
15155580
11074002
|
CDKN1A
|
CCNE2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
17145710
23443559
26186194
28514442
9840927
9840943
15232106
26496610
24358021
|
TP53
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
16103197
22467867
18555006
8631601
11402335
19649205
22020338
21164364
17265068
16764954
15775976
22056554
18275833
21483786
10348346
19216023
12384561
12091906
19901969
11360201
15205322
11818069
21892281
10980602
11739748
11559812
24672805
10097151
17907153
19244234
15361884
10652576
9436028
21447739
20569441
21555589
21637567
10816133
9774662
19240179
|
SP1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10649433
22025288
15067344
17370299
21830402
17225865
12134028
19115249
16239970
|
ETS1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17370299
22714536
11234019
19240179
|
ETS2
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17370299
11234019
19340300
|
E2F2
|
CDKN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18319725
11883935
|
CDKN2A
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15856024
15989956
9724636
19960022
12740913
17158541
12640129
19590512
|
RUNX2
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23159876
11106645
11331591
24404380
|
SP1
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
10091149
16575855
9666093
10775443
12138160
11348466
17698844
16564026
10082137
7504695
7590335
|
COL1A1
|
ITGA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11359786
7688313
11856343
2156854
|
COL1A1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7716514
10464311
7688313
|
COL1A1
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
1693626
16189514
|
COL1A1
|
ITGA11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11359786
10464311
7688313
11856343
2156854
|
TP53
|
DDB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12771027
22336944
15856024
12509284
12170778
16357511
12967652
15927209
11971958
|
CAV1
|
EGFR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
11102446
17517963
18458534
19411448
20855962
21051947
21150282
21729786
22411312
22874531
23907124
25364523
26828520
|
TP53
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20190820
18359760
9664135
10029407
8152794
11713584
8887630
9285564
19597475
11546792
1586628
18604200
18391986
|
ESR1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12894229
12421825
8200909
21705183
|
PGR
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22542550
8347631
16449295
17074804
|
SP1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
1282800
17616668
18575762
19538880
15665278
18202149
20435036
21705183
18007664
21464950
23821666
15533438
9819401
10830317
8393457
16087726
20407012
18391986
|
MAPK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
12556561
1651322
17081983
3138233
15901825
1939237
91332050
2543683
2115882
17192257
1651323
15302935
|
TGFB1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20953304
32103204
19132220
28943431
|
EGFR
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
19104148
27401557
15371335
16099633
22558232
30747223
12040186
26509276
24816560
12740122
25500543
17318191
19568798
21423209
14585353
34227224
23640056
17496910
17052462
24240237
25164010
14517306
21903109
22200182
16952352
20858269
28035485
9233779
|
EGFR
|
SHC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
24212772
9507002
16273093
11791173
8760305
8662772
|
EGFR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
20809984
17284441
16713569
11887937
|
EGFR
|
CALM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
19901323
20029029
16497976
15592455
25402006
17389395
18578522
16799092
20068231
7925415
3415247
8639568
18669648
12153558
24658140
17287340
2843348
14960328
15212693
18707149
17016520
|
EGFR
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12556561
15531749
|
EGFR
|
CAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17145710
31980649
22411794
9374534
19446582
16799092
12388423
15657067
24658140
19625610
16407214
18789131
25402006
15951569
10781609
16332692
|
PLAT
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
25879083
10632583
1502153
11560943
|
SERPINE1
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
1500157915001570
15001579
16713569
|
TFPI
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8824219
|
MMP9
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11279011
|
ETS2
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
8552081
10358095
20534573
11782450
15572696
|
ETS1
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
8552081
10358095
20534573
11782450
15572696
|
MAPK1
|
FGF23
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
19652666
12419216
18452557
12974390
|
MAPK1
|
SMAD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
10197981
16156666
27153775
29577978
|
SP1
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12220517
16797880
20506264
20121399
20882567
18372343
10727414
21170990
17889508
|
MAP2K1
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
149.0
|
1.0
|
Omnipath
|
21675959
9694850
17081983
10757792
11319218
18799465
15592455
12788955
19415658
12697810
17389395
9447970
15342917
8226933
15851026
12270934
12644307
17255949
10998418
11242034
1378617
1381507
17906627
11986622
8376945
8157000
7992057
11948414
9731057
19651622
11251083
11266467
18707149
14743221
11279118
11704645
12750173
12932319
16497976
11337027
23331499
12048245
7559390
17272394
15811950
19494114
18669648
18691976
11741894
15972258
19053285
16094384
17192257
7898932
24623782
9166761
19369195
21336309
12920017
15466214
17016520
19901323
1712480
19690332
11823456
9032297
11134045
12876277
19534553
10995751
20068231
21506533
8223433
8248196
16153436
12594221
10567369
19933846
17563371
11730323
29175850
11352917
16135787
15951569
19058874
15212693
23241949
9560161
91184134
18083107
16887817
18578522
17569879
21071413
9148935
18452278
1330321
8670897
19541618
10777511
15935618
12925710
11971971
9765155
11136732
11118451
12082107
12952943
10746662
21768338
|
MAPK1
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21494553
21449613
25241761
16045329
23991633
20361728
11570862
22521293
11948414
|
MAPK1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16039586
28646232
18451303
|
MAPK1
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19318349
20882567
16377629
18775330
8226933
14744793
16079281
11904305
9604935
15212693
14593115
8388392
|
MAPK1
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
23331499
10197981
34504019
18775330
20659902
8226933
9620846
16156666
9604935
18988627
12193595
11027280
8388392
27153775
31995604
|
MAPK1
|
PGR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
8702648
17173941
18202149
10628747
15798179
17717077
12529413
15212693
10655479
11110801
|
MAPK1
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11287604
11481231
|
MAPK1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16954218
10551817
18519666
18687685
26784107
|
MAPK1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
15655247
10949034
15528270
18372406
15461668
12118371
12466266
7495695
17615152
15059947
16076840
7491495
12093745
10409727
9528769
7838153
|
MAPK1
|
NR4A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17681692
|
MAPK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
14965474
9765199
15116093
21675959
23443559
10781582
25241761
10446957
10958792
11409876
11709713
21147777
10673501
11551930
15867353
11875057
12091386
|
MAPK1
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
24342355
17290218
|
MAPK1
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
17289590
19914168
9335504
19914161
|
MAPK1
|
PPP2R5C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16456541
|
TP53
|
PPM1D
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18333294
19015127
11101524
22405851
20093361
|
PPM1D
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15870257
17936559
23666059
28903382
|
PPP2R5C
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17245430
25241761
|
HIF1A
|
TF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19828020
9242677
12393745
|
TF
|
TFRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
11027676
21788477
9546397
6270680
16271884
29302006
14691533
12210842
20404192
16354665
6268632
|
ESR1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20080630
16115928
22787161
12750288
20696891
17681750
17699779
|
HIF1A
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12542982
17390008
9537326
15780936
11696352
10469629
17236590
20706634
15629713
11007955
|
AHR
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17070097
15111621
11191113
20478272
|
ETS1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12145208
19022222
8649821
10510472
|
TP53
|
SERPINE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18431400
23665346
23063463
7479001
11470783
20947822
|
TP53
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11564862
20697347
20729811
21691299
19411072
24473123
20064927
18245266
18758483
18372914
|
TP53
|
IGF1R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
15131018
11001824
12089352
20633551
24205274
17097318
10023442
17600529
17014845
8710868
12444079
16181796
22033326
|
TP53
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17311279
15899818
17077165
18635530
|
TP53
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18980971
22451655
23048035
10029407
9343394
19853299
11792711
19939245
17088079
17258390
|
TP53
|
HLA-DRB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15289308
16230375
11382926
15964798
|
TP53
|
CAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10684646
20610713
17014845
11076533
|
TP53
|
IGFBP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10101800
23810988
15661074
7566179
15713654
18084616
9525742
20003326
|
TP53
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12732139
10618379
22264233
23706820
14514686
8183578
14761612
16138117
18593586
23063463
8119773
|
TP53
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
19846904
15790310
11118296
11384995
21611785
7478550
15967108
18419600
19244234
9865734
18769160
|
TP53
|
FLT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16432214
20080630
17242190
20422012
|
TP53
|
THBS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12609716
10719731
10101800
24195060
10029407
16406676
19826414
9833779
12719977
9017002
22028325
10224095
9849855
7521539
|
PPP1CB
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16501611
15178317
|
GSK3B
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
23840442
12064478
11709713
9372954
11483158
16552184
17570479
14744935
16713569
21929745
12048243
21900206
|
TP53
|
IGFBP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7566179
17409411
18431400
|
TP53
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9537326
16713569
12124396
15629713
16882692
|
RHOA
|
PPP1CB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|
MYL9
|
PPP1CB
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|
PPP1CB
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17318175
|
CD14
|
IL10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
IFNG
|
IL10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
IL10
|
ARG2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
10925299
11207245
11438547
11875494
12193690
12811837
12818165
14607900
15282297
15579430
15749903
15833879
16200688
16424049
16713974
17404308
17485448
20184663
20435894
20547845
21115385
21191065
21220452
23124025
23508573
24378531
26755705
9834059
|
IL10
|
THBS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
10925299
11207245
11438547
11875494
12193690
12811837
12818165
14607900
15282297
15579430
15749903
15833879
16200688
16424049
16713974
17404308
17485448
20184663
20435894
20547845
21115385
21191065
21220452
23124025
23508573
24378531
26755705
9834059
|
IL10
|
ID3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
10925299
11207245
11438547
11875494
12193690
12811837
12818165
14607900
15121845
15282297
15579430
15689496
15749884
15749903
15833879
16200688
16424049
16713974
17404308
17485448
18832382
20184663
20435894
20547845
21115385
21191065
21220452
23124025
23508573
24378531
26755705
9834059
|
SP1
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
20072143
22469463
12493739
17376198
12847250
19564345
10903771
10657644
18843277
21309719
10861063
16871431
19307576
11278848
22940633
16413748
17202341
15972681
|
CTNNB1
|
AXIN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
24447505
15473860
11809809
22615875
11809808
12711682
11940574
|
CTNNB1
|
AXIN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10966653
19751508
7542250
8666229
17143292
11955436
11967263
23343194
22270359
9554852
22699938
16039586
16940750
9566905
19619488
15766563
12051714
|
AXIN2
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15611123
10966653
10911903
888800000547
9554852
22745173
9566905
22322943
|
TGFB1
|
ID3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
27.0
|
1.0
|
ACSN
|
11133108
11708773
12490555
14557817
15111329
15181457
15252039
15548370
16474430
16607286
16716598
17615296
17934056
18403754
19010789
19109155
19920116
20519943
20644162
21041997
21278795
21900405
21909923
22703233
7594497
9157999
9335507
|
CALM2
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19358819
20705923
22486744
24379783
11397791
|
ITGAV
|
ITGB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
10837075
11146654
14697347
15031725
18353785
22035837
22470492
9295024
9763615
|
ITGAV
|
ITGB5
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
10837075
11146654
14697347
15031725
18353785
22035837
22470492
9295024
9763615
|
SP1
|
ITGB5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
10964912
11007770
11013220
15001984
17705132
18353785
21252118
23338822
|
ITGB5
|
ITGA2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
5.0
|
1.0
|
ACSN
|
22470492
24309651
26519775
9295024
9763615
|
ITGB5
|
ITGA1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
5.0
|
1.0
|
ACSN
|
22470492
24309651
26519775
9295024
9763615
|
FN1
|
ITGB5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1694173
1532572
17015452
18480047
|
VTN
|
ITGAV
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
7525578
7559467
17968485
9251239
7685013
9443892
|
ITGAV
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
10022831
10545505
10837075
11146654
11335727
11532940
11553709
12000961
14697347
15031725
16919435
18353785
19161977
19339212
19449109
22035837
7512751
7529872
7657702
8636223
8755653
9295024
9763615
|
ITGAV
|
ITGB3
|
â—¼ SHARES_COMPLEX
|
|
|
23.0
|
1.0
|
ACSN
|
10022831
10545505
10837075
11146654
11335727
11532940
11553709
12000961
14697347
15031725
16919435
18353785
19161977
19339212
19449109
22035837
7512751
7529872
7657702
8636223
8755653
9295024
9763615
|
SP1
|
ITGAV
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10504395
23319049
12136940
23345412
|
FN1
|
ITGAV
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
1694173
18480047
1532572
19738201
23154389
17015452
|
COL4A1
|
ITGAV
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14610079
|
VTN
|
ITGAV
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23154389
|
HGF
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11290563
12649206
15059978
16212809
17145802
18633355
19631971
20303741
22763439
23402812
23667593
26366398
26819959
27474009
28475121
9242465
|
HGF
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11290563
12649206
15059978
16212809
17145802
18633355
19631971
20303741
22763439
23402812
23667593
26366398
26819959
27474009
28475121
9242465
|
FGF2
|
HGF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11874475
18232728
18633355
18776941
19508171
19631971
21098712
22652804
23123598
25374926
9242465
|
SP1
|
HGF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9223667
17967179
12482909
|
HGF
|
FN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8780385
25241761
15717924
|
HGF
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
57.0
|
1.0
|
Omnipath
|
17145710
22897854
15167892
1655405
20624990
19433454
23331499
17804794
1846706
28475121
22001117
16537482
15218027
27147579
24362531
17667909
16397249
20178463
17981115
28534512
8380735
18495663
14685170
|
PDGFB
|
PDGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9334164
10508235
1311092
8900172
|
PDGFB
|
THBS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9334164
10508235
1311092
8900172
|
PDGFB
|
THBS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9334164
10508235
1311092
8900172
|
SP1
|
PDGFB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22415074
11222751
15175554
11967988
8662647
|
VTN
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
2412224
2420006
7685013
7542669
|
ITGB1
|
ITGA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
12626562
19161977
19454690
19487819
22470492
9003039
9456329
9763606
9973479
|
ITGB1
|
ITGA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
29.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
12731048
15866889
16076871
16919435
17522712
18037882
19161977
19339212
19454690
19487819
20644254
20814939
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
ITGB1
|
FN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGB1
|
ITGA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
29.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
12731048
15866889
16076871
16919435
17522712
18037882
19161977
19339212
19454690
19487819
20644254
20814939
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
ITGB1
|
ITGA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
12626562
19161977
19454690
19487819
22470492
9003039
9456329
9763606
9973479
|
ITGB1
|
FN1
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGB1
|
FN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
FGA
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15031111
7716514
|
THBS1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15292271
|
COL18A1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12682293
|
THBS2
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15292271
|
COL2A1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9685391
7688313
|
ADAM17
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22413019
14970227
30455686
|
VCAM1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12097820
22623428
19738201
19057841
11751331
|
NPNT
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11470831
|
FN1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
9842903
22451694
17015452
18480047
19738201
7688313
1694173
6325925
25237190
26456826
10772816
7626807
21985969
6284125
1532572
11010812
8120056
|
PLG
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15247268
|
SMAD2
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11074002
11279127
15265520
16179589
16713975
21042762
21614932
22331441
23784029
9670020
|
SMAD2
|
SMAD7
|
â—¼ PROTEIN_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11074002
11279127
15265520
16179589
16713975
21042762
21614932
22331441
23784029
9670020
|
SMAD2
|
SMAD7
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
10.0
|
1.0
|
ACSN
|
11074002
11279127
15265520
16179589
16713975
21042762
21614932
22331441
23784029
9670020
|
TGFB1
|
SMAD7
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
11133108
11708773
12490555
14557817
15111329
15181457
15252039
15548370
16474430
16607286
16716598
17615296
17934056
18403754
19010789
19109155
19920116
20519943
20644162
21041997
21278795
21900405
21909923
22703233
7594497
9157999
9335507
|
SMAD2
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15183844
10887185
10753944
10843994
10559222
|
SMAD7
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10887185
15855807
9886263
20631490
22656308
19214138
23633623
14600158
10753944
11912247
11385614
11180003
17928287
19010789
22496417
22841502
17074765
15496141
11448947
|
CTNNB1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
15684397
21071413
18988627
|
TGFB1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19010789
14718519
16474430
17934056
20519943
9335507
21900405
11133108
14557817
15548370
19920116
|
SMAD7
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
17438144
21071413
9892009
9892110
|
SMAD2
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013220
11074002
11279127
11283613
11283614
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21252118
21614932
2191300
22331441
23140366
23338822
23869868
8515656
9312026
9389648
9618481
9670020
|
SMAD2
|
SP1
|
â—¼ SHARES_COMPLEX
|
|
|
40.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013220
11074002
11279127
11283613
11283614
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21252118
21614932
2191300
22331441
23140366
23338822
23869868
8515656
9312026
9389648
9618481
9670020
|
TGFB1
|
SMAD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD2
|
ITGA11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
11074002
11279127
11792802
12702545
12809600
15265520
16179589
16713975
21042762
21614932
22331441
23784029
9389648
9670020
|
IL18
|
SMAD2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
10.0
|
1.0
|
ACSN
|
10679398
11592085
14504095
14662834
15099563
15802534
26885855
27048821
27066895
9469432
|
SMAD2
|
IFNG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
24.0
|
1.0
|
ACSN
|
10925299
11074002
11279127
11399519
11792802
11875494
12193690
12702545
12809600
15265520
15644117
16127449
16179589
16713975
17260466
17689680
21042762
21614932
22331441
23390297
6357187
8871614
9389648
9670020
|
SMAD2
|
SERPINE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15198928
23063463
19132220
11879191
|
TGFB1
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
15548370
19010789
10678166
16474430
9311995
23831640
17934056
20519943
24075003
11792802
11133108
21900405
14557817
11278410
19920116
9865696
|
SMAD2
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19558215
10878024
12631740
11013220
11114293
|
IFNG
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
SP1
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24019072
17023546
12576336
8756632
18793716
9503023
|
ETS1
|
MMP9
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
10048576
15001984
15003528
15111329
15181457
16079281
16391805
16556862
16682805
17615296
17872466
18337545
19208835
19564415
20589835
21041997
21081489
21317430
22439866
22608498
23691193
24376839
7512751
7528107
8844971
9157999
9811054
|
SP1
|
MMP9
|
â—¼ UP_REGULATES
|
✅
|
+
|
21.0
|
1.0
|
ACSN
|
10048576
10964912
11007770
11013220
11114293
15001984
15592504
16079281
16556862
16716598
16831886
17490644
17705132
18353785
18832382
19564415
20589835
21252118
22439866
23338822
8844971
|
FOSL1
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16554298
22514284
22514348
15319566
17572495
|
ETS1
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22270366
15949416
16722933
11556732
22206665
10949659
|
SP1
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8226872
24755270
18028425
9514098
9520415
23799155
20529870
21840940
7860222
17049831
21963718
18357389
9150367
11060311
19616522
11830485
9748266
20638438
|
CTNNB1
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17306568
17666529
23343194
21285352
15576399
21151179
22761862
22290435
16039586
19619488
19623618
17143292
|
ETS1
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10048576
16391805
17615296
15111329
19564415
9157999
16079281
21081489
21041997
15181457
|
MMP9
|
TGFB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10652271
21900405
25241761
|
TGFB1
|
ITGA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
48.0
|
1.0
|
ACSN
|
10671552
11133108
11348595
11955436
11967263
12051714
12426320
14557817
15001769
15279786
15548370
16039586
16099633
16371504
16474430
17143292
17303408
17660363
17928543
17934056
17936032
18037882
18590585
19010789
19029934
19109155
19171760
19619488
19734908
19920116
20519943
20644162
20705860
21278795
21666923
21900405
22007144
22174153
22203675
22674073
22703233
23343194
24023259
25730849
7542250
7575488
7594497
8666229
|
TGFB1
|
ITGA3
|
â—¼ SHARES_COMPLEX
|
|
|
48.0
|
1.0
|
ACSN
|
10671552
11133108
11348595
11955436
11967263
12051714
12426320
14557817
15001769
15279786
15548370
16039586
16099633
16371504
16474430
17143292
17303408
17660363
17928543
17934056
17936032
18037882
18590585
19010789
19029934
19109155
19171760
19619488
19734908
19920116
20519943
20644162
20705860
21278795
21666923
21900405
22007144
22174153
22203675
22674073
22703233
23343194
24023259
25730849
7542250
7575488
7594497
8666229
|
THBS1
|
TGFB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10657674
11982756
14568985
14996710
21900405
22943793
8349738
|
TGFB1
|
PDGFA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11133108
11708773
12490555
14557817
15111329
15181457
15252039
15548370
16474430
16607286
16716598
17615296
17934056
18403754
19010789
19109155
19920116
20519943
20644162
21041997
21278795
21900405
21909923
22703233
7594497
9157999
9335507
|
TGFB1
|
ETS1
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
11133108
11708773
12490555
14557817
15111329
15181457
15252039
15548370
16474430
16607286
16716598
17615296
17934056
18403754
19010789
19109155
19920116
20519943
20644162
21041997
21278795
21900405
21909923
22703233
7594497
9157999
9335507
|
HIF1A
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16896927
17053163
15611046
19211927
21209004
21057546
21055290
|
SP1
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12186868
9580699
2808430
12615726
22415074
27974707
12138160
10964912
9242631
15178441
23437118
23936544
11114293
8325508
16714330
11278686
10212284
9837963
11054406
23806282
15979845
|
THBS1
|
TGFB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
22943793
8349738
21900405
1550960
|
MMP2
|
TGFB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10652271
25241761
16189514
21900405
|
TGFB1
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12867422
25241761
16189514
2119582
|
TGFB1
|
PDGFA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19010789
16474430
17934056
18403754
20519943
16607286
21900405
11133108
14557817
15548370
19920116
|
JAG1
|
NOTCH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
23331499
18660822
22330899
21071413
16921404
18988627
10958687
22363130
10551863
22353464
|
THBS2
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14699013
|
VCAM1
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22623428
19738201
11751331
|
FN1
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9117345
9842903
19738201
11010812
|
THBS1
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14699013
|
FN1
|
ITGB7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1372909
|
AXIN1
|
FZD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
GSK3B
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
102.0
|
1.0
|
Omnipath
|
20128690
16944320
11738041
20043192
12511557
11967263
16890161
22613765
14663202
23602568
8524413
24451375
19303846
12554650
8638126
22509369
18593713
16199882
21988832
23331499
19759537
10428961
9482734
22270359
19202075
17570479
16293724
15327768
10581160
17318191
11487578
22773187
26496610
16568235
17318175
19131971
15465828
26912724
25241761
24976009
21242974
22682247
10228155
23579495
12584189
23959799
15020233
10421629
10488109
11278246
9501208
18632848
10481074
10535959
10318824
9554852
17601533
9832503
21502811
9734785
23455922
|
AXIN1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
20128690
20531388
16890161
27902311
22509369
18593713
16199882
23331499
9482734
21071413
26496610
19244247
22773187
17318191
10196136
18988627
17208333
19131971
24976009
22682247
10228155
12805222
12000790
10488109
9501208
9601641
18632848
9554852
19166851
23959799
12421363
9734785
11940574
|
CD14
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
21737330
12752666
15814722
16115877
14739303
21737329
|
IL2RG
|
IL18
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
CD14
|
TIMP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
SP1
|
CD14
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11698458
17203216
12213324
7512565
|
PDGFA
|
THBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9334164
10508235
1311092
8900172
|
THBS1
|
ITGA3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10196234
|
THBS1
|
ITGA2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
2478219
|
THBS1
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
2478219
14963009
|
THBS1
|
FN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
19542224
11773026
18042364
18226512
|
ITGA5
|
FN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGA5
|
FN1
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
SP1
|
ITGA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22227038
18775869
15825163
24130169
|
VTN
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11331280
23154389
|
COL18A1
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11158588
12682293
|
FN1
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
11423542
1694173
6325925
11801679
18480047
16457822
10772816
9211865
1532572
25237190
26456826
19738201
23154389
22451694
17015452
20643357
|
ARHGAP5
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
32203420
9407060
10592173
8537347
12842009
|
DVL3
|
FZD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
GSK3B
|
FZD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
FZD1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
7641885
15265686
19718039
21602792
210606194
8655584
19705439
19029934
20093472
17430994
21606194
17884187
14747478
22017973
22433869
17143292
20006983
19072724
14704854
16965538
16443747
22007144
16547521
19020754
20940130
21640127
21087212
17127310
21796133
|
HIF1A
|
CAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10804084
16110315
16127144
17533374
20427344
20535745
20855962
21051947
21765015
22006996
22850421
22988108
24006507
25043024
25103413
25732824
|
HIF1A
|
TFRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10446188
18519569
23160040
10518614
16510596
10446187
13679021
|
HIF1A
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19492421
16399861
17536272
17942638
|
HIF1A
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16099863
17028975
|
HIF1A
|
SERPINE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
19828020
10590062
11877282
17570486
18381294
9427542
14708599
17721610
15968405
16778202
17197388
19132225
20216986
21132271
14567996
14978738
20136501
17384280
12393531
19490965
8672239
11313255
20351105
|
HIF1A
|
TGFB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7539918
8943284
1823643
12829734
9159130
10712429
13130303
11566883
12080085
10403805
9746763
15451019
11790723
9278421
16887934
|
HIF1A
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
17615296
9157999
9278421
11708773
16716598
12080085
10403805
16887934
15181457
7539918
12490555
1823643
12829734
13130303
15451019
9746763
8943284
15111329
9159130
11566883
21041997
|
HIF1A
|
FLT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7539918
1823643
12829734
9159130
13130303
9746763
12080085
11566883
10403805
8943284
15451019
11528470
9278421
16887934
9295307
|
SP1
|
SERPINE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15178441
23235480
12105191
10880342
1634545
11423472
17890327
8342330
9525928
15039136
11251188
|
VTN
|
SERPINE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11113116
12808446
11796824
8830783
16713569
9065424
|
SERPINE1
|
PLAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
2110366
16713569
8607113
3090045
|
PLG
|
IGFBP3
|
â—¼ CLEAVAGE
|
✅
|
|
10.0
|
1.0
|
Reactome
|
8817670
7527330
17047378
8964575
11739083
7588299
8894645
12466191
12379487
10990447
|
PLG
|
ITGA9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15247268
|
PLG
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10978167
|
PLG
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
12604689
10978167
9020112
|
SP1
|
ITGA11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
10964912
11007770
11013220
15001984
17705132
18353785
21252118
23338822
|
ETS2
|
IL12B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9497375
8958954
10657616
9234715
16518544
|
ESR1
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11773442
17535799
15033483
22031296
15496458
|
SP1
|
CAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15531587
10684646
23280667
21631282
17108117
|
SP1
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12759366
19105596
15722551
18624763
12684688
9614091
10574932
10713142
15061658
12270858
15180995
|
SP1
|
CYP1B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12801909
23376040
|
SP1
|
IGF1R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10720440
21447702
7497000
15345673
17170218
7491107
17049831
17014845
10982795
17486080
|
SP1
|
HLA-DRB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14561739
18097593
15142888
20515942
|
SP1
|
IL12B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16518544
20121399
15270850
19134014
|
SP1
|
TIMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
22415074
16931573
9478976
11348466
15048879
11830330
|
SP1
|
PDGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
15297375
9453298
9321833
9351401
22964636
7499234
10364563
11823426
|
SP1
|
COL2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18044710
11447232
12888570
18065760
16650379
12637574
|
SP1
|
PGR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12554796
12706304
15019994
20087433
10894148
|
SP1
|
PRLR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21238538
16651265
21670145
9748306
|
SP1
|
AHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
9778040
16410262
21569840
20478378
|
SP1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12237165
19351845
11345900
21235772
23209644
12429135
18006846
10982795
22622808
15691879
21191649
|
SP1
|
ITGA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8887648
20090957
11238113
11313353
|
SP1
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
16453304
19061309
19853299
16575904
21045016
10506168
21520171
21469139
15317818
17258390
19126647
|
SP1
|
APP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19049493
8427604
15673661
9361293
21557719
18449948
14701757
8015372
|
SP1
|
PLAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10452548
21437359
2172788
18419748
9851700
|
SP1
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15908479
16341057
9671487
1845987
8803927
2542772
7565693
15608673
9566920
1404598
2170405
10421838
|
SP1
|
IGFBP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12200149
11517158
15247904
|
SP1
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11910354
12473536
9223667
15067326
21831840
17283128
|
ETS1
|
ITGB3
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
10048576
15001984
15003528
15111329
15181457
16079281
16391805
16556862
16682805
17615296
17872466
18337545
19208835
19564415
20589835
21041997
21081489
21317430
22439866
22608498
23691193
24376839
7512751
7528107
8844971
9157999
9811054
|
ETS1
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12039986
16391805
12122099
17088079
|
MAPK7
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8761310
12048211
20361728
25885538
8552081
11948414
|
FN1
|
ITGA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7688313
|
VTN
|
ITGB8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
7525578
7559467
17968485
9251239
7685013
9443892
|
VTN
|
ITGA2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
2412224
2420006
7685013
7542669
|
VTN
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
7525578
7559467
17968485
9251239
7685013
9443892
|
VTN
|
ITGB6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8120056
|
VTN
|
ITGA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7559467
|
VTN
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16195248
11331280
|
VTN
|
ITGB8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11156415
|
FN1
|
ITGB6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
1694173
18480047
1532572
17015452
|
FGF2
|
SDC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20382221
8621465
16982797
1101561416982790
8609172
11015614
|
ESR1
|
IGF1R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17170218
20021813
16087727
19250214
10982795
24281069
18414489
15595626
|
IGF1R
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17496910
22558232
12040186
19568798
14585353
|
F2
|
IGFBP3
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
8817670
11739083
12379487
12466191
17047378
|
MMP2
|
IGFBP3
|
â—¼ CLEAVAGE
|
✅
|
|
6.0
|
1.0
|
Reactome
|
8817670
9922210
7523391
12379487
12466191
17047378
|
FN1
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11423542
1694173
18480047
1532572
8663002
17015452
|
FN1
|
ITGA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7559467
7626807
|
FN1
|
ITGA9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11839764
|
FN1
|
SDC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10772816
1077281610772810
|
FN1
|
ITGA2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8663002
|
GSK3B
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
18045539
25241761
|
ESR1
|
PSMD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18457947
9253789
12648521
11696545
23580568
|
MAP2K1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17081983
21105670
16964243
14617795
30711629
18547980
8382613
17188038
17192257
15020233
|
GSK3B
|
DVL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
GSK3B
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
183.0
|
1.0
|
Omnipath
|
22415718
11967263
27158593
29455668
19303846
19797085
8638126
19293931
23056571
22662165
25352148
16611981
27068260
28337019
10671551
21743491
20688898
16293724
23721711
23552738
18687691
28977889
19622173
12051714
25241761
27683053
28549350
22699938
19565571
23076981
21562161
19575820
20219694
20537194
10330181
21986938
29183346
27773936
11251183
19711366
21035499
19675674
7542250
23151663
24451375
14663202
23804296
8524413
25639486
23770025
18070361
26892600
30143633
9233789
19667122
27507058
19061640
19223551
29387014
23331499
16199882
11533658
18644116
24501426
24913829
11835406
17318191
26014148
25366337
28183999
22640743
26910375
12000790
12114015
18387957
19107203
9832503
16371461
29805709
27462866
20137080
27902311
12040186
19576224
25644994
12615961
19060929
25897075
12851486
15465828
17053159
18952601
10228155
15020233
17444818
20140245
26453498
17052453
16944320
24015932
23602568
24975844
24931005
28948000
20080742
23209942
30271168
28220106
16520547
28430641
11818547
25546293
27672271
11955436
11154277
26373837
16039586
23778311
28697793
20302655
25136145
26905812
22216350
8666229
12957350
23109003
10074433
28529629
20215423
21329734
11254732
9501208
27098453
27281614
30279527
19631635
25482131
18455992
24403311
11274345
|
GSK3B
|
DROSHA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20554852
27907888
25699712
21674040
25727520
|
GSK3B
|
NOTCH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
28.0
|
1.0
|
Omnipath
|
16944320
15465828
11967263
14663202
8524413
20068231
12794074
21828089
17570479
9832503
15020233
18669648
15302935
|
GSK3B
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10428798
10949034
17609434
15461668
9528769
12118371
15059947
16076840
17570479
7491495
12093745
8308015
15212693
15528270
7838153
|
MET
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
17496910
25163657
24511551
22558232
11929826
16909210
24342833
12040186
26654598
19568798
14585353
23083465
|
ESR1
|
FOSL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22514284
20034404
|
ESR1
|
CYP1B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16010691
17511620
15126349
22761658
18414489
|
ESR1
|
CAV2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12711000
12138116
18414489
|
ESR1
|
PGR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
12829318
12554765
12446585
11000528
15019994
8043503
23027806
9058379
9717846
18414489
12706304
10835496
16293641
18784357
12761896
8145766
22543272
15743834
8530508
10894148
|
ESR1
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22052999
11029009
10690351
14742696
19914929
|
AHR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12612060
17392787
10620335
|
PGR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
22396492
16168121
12612073
11000528
18988627
26153859
|
AHR
|
CYP1B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
17012224
9478971
19287966
17709388
23275542
21742528
12801909
19376845
17511620
19805408
12376470
12859982
18059014
17785579
14728982
19789301
16115918
10051545
21703235
24299737
22138065
22187486
19126602
12213569
|
PDGFA
|
THBS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9334164
10508235
1311092
8900172
|
PDGFA
|
THBS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9334164
10508235
1311092
8900172
|
F2
|
FGA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
25241761
2133223
2742826
1587268
|
FGA
|
PLAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
3088041
11170397
|
F2
|
GP1BB
|
â—¼ CLEAVAGE
|
✅
|
|
4.0
|
1.0
|
Reactome
|
10781579
8338946
2019570
9888880
|
F2
|
VWF
|
â—¼ CLEAVAGE
|
✅
|
|
7.0
|
1.0
|
Reactome
|
19240027
8052958
2104766
15705787
1851341
2109644
1973901
|
F2
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9058715
10978167
15707890
10644723
14652070
11356985
23450633
18250335
12563219
22972936
|
F2
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10978167
1135698510978160
11356985
|
TIMP1
|
MMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
19010413
12475252
|
COL2A1
|
ITGA2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7520045
10772239
|
VWF
|
ITGA2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
31035301
1737795
|
KLF2
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
22987017
15718498
22178876
18218985
15834135
20551324
16043642
|
COL5A1
|
SDC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11751872
|
COL2A1
|
ITGA10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9685391
|
NPNT
|
ITGA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11470831
|