CREB1
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7721872
12658356
|
PXN
|
FN1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21985969
8208414
|
SDC4
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11805099
|
RIPK4
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1232253
23371553
|
LRP6
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
16273260
23371553
|
DVL2
|
RIPK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
16273260
23371553
|
LRP6
|
DVL2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
16273260
23371553
|
DVL2
|
RIPK4
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
16273260
23371553
|
RIPK4
|
DVL2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
1232253
23371553
|
HIF1A
|
ANGPTL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19828020
12099716
|
ARNT
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17991765
|
ESR1
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12603855
26790618
|
RELA
|
CFTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11114294
|
RELA
|
COL2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19022820
|
RUNX2
|
COL2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11331591
16029574
|
ESR1
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10935492
12878732
|
ESR1
|
TGFB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12580758
11159847
|
ESR1
|
RAC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21118977
11060289
|
ESR1
|
PRKCD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22430216
18414489
|
RELA
|
F2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11463837
19351910
|
F2
|
PLAU
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10996659
8428004
|
FN1
|
TNR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7499434
7527058
|
FN1
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11476890
16919435
|
FN1
|
SDC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23290138
27235146
|
PRKCA
|
GIPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5212824
10911369
|
HIF1A
|
RAC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19132225
20001745
|
LRP6
|
RIPK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
16273260
23371553
|
LRP6
|
RIPK4
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
16273260
23371553
|
RUNX2
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19915614
16166639
|
THBS1
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11606713
10900205
|
PDPK1
|
PRKCD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12840507
9889098
|
PDPK1
|
PRKCA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12840507
9889098
|
PRKCA
|
PRKCE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16810323
5218785
|
RAC1
|
PRKCA
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5218533
16628218
|
PRKCE
|
PRKD1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
0809661105
19011111
|
RAC1
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18212043
18066058
|
RELA
|
REL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5211837
10498867
|
SDC4
|
SDC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18093920
0708909105
|
SDC3
|
SDC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18093920
0708909105
|
SDC2
|
SDC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18093920
0708909105
|
SDC2
|
SDC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18093920
0708909105
|
SDC4
|
SDC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18093920
0708909105
|
SDC3
|
SDC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18093920
0708909105
|
DDB2
|
SDC4
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.81
|
0.8
|
PKG
|
28854368
|
COL4A1
|
COL4A2
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
DVL1
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
COL6A1
|
COL6A2
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
REL
|
SDCB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27609421
25416956
|
SDCB1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
31413325
|
GP183
|
SDC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
FGF1
|
SDC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
SGTA
|
SGTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HuRI
|
32296183
|
GP183
|
SDC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
FGF1
|
SDC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
PDPK1
|
FGF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
31980649
|
FGF2
|
SDC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
16982797
|
PDPK1
|
SDC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
31980649
|
FYN
|
PRKCD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
FN1
|
TGM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.84
|
STRING
|
36370105
|
FGF2
|
SDC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8344959
16982797
|
SDC4
|
GIPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10911369
|
SDC2
|
PDPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
28514442
32707033
|
RAD18
|
PCNA
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
19706603
|
FYN
|
SDC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9553134
16189514
16713569
|
FGF2
|
SDC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
28514442
16982797
|
RAD18
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21967848
28924044
21227930
20675655
32701997
21858012
20064529
28831681
33508099
17108083
18363965
23345618
26170230
17720710
24958773
15359278
31873223
18245774
30700555
31887036
30563767
20600238
22904075
31160570
27377895
|
SDC4
|
SDCB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12241528
12842047
|
REL
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
RELA
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10201951
|
PLG
|
PLAU
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
2521625
2935528
1829461
|
PLAU
|
PLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
3920216
2829380
4226004
|
THBS1
|
PLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
6438154
2522013
|
RELA
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10541434
11277268
|
ZNF384
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19429913
|
DDX58
|
TANK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
19668221
19479062
17327220
|
DVL3
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
12533515
|
RUNX2
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17350616
|
F2
|
F2RL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
873923
8615752
10079109
|
HIF1A
|
TGFB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10831118
16611863
|
HIF1A
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20631454
19285046
19950212
|
RELA
|
IL7R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18226221
|
PRKCE
|
PRKD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10092595
12407104
|
RELA
|
TNC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20723226
9154819
|
THBS1
|
TGFB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22943793
8349738
21900405
|
COL1A2
|
SGTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
PTK2
|
PXN
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
15688067
|
NHEJ1
|
SDC4
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.9
|
0.9
|
PKG
|
28854368
|
F2
|
F2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
SDC4
|
SDCBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
COL4A1
|
COL4A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
PXN
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
25795725
|
PCNA
|
POLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
PTK2
|
PXN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
DVL1
|
DVL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
32296183
10330181
|
SDCB1
|
SDC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
18256285
31930596
9391086
22660413
|
HIF1A
|
ARNT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
12391259
10085255
16954218
7836384
17916562
26496610
8663540
34592152
14764593
20603618
14668441
21512126
11606485
26350169
9079689
24056783
19845609
27684187
11782478
19168635
23363003
26160453
28628118
15850782
17197389
21620138
15833858
23086815
24434214
20458141
18024476
23458834
12810720
28514442
15347669
9704006
27320910
20562859
11829741
15031145
21435239
20049704
15479785
20932347
12393189
11025203
16861921
9159130
10671489
16520375
15615775
17213817
28205554
23796364
15319539
11593383
19251694
20699359
|
PCNA
|
RAD18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
ARNT
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
RAD18
|
PCNA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10884424
15280666
15688063
16611994
16824193
17652783
18157158
18196958
18363965
18498753
19013543
19258535
19396164
20129063
20675655
|
RAD18
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
18363965
19706603
17652783
18196958
18498753
20129063
21227930
10884424
19013543
18157158
15280666
19258535
16611994
19396164
20675655
|
COL5A1
|
SDC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11751872
|
TIAM1
|
RAC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11955434
12447393
12829230
15611338
15967165
20841469
|
PRKCA
|
TIAM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9407095
10212259
10734127
|
TIAM1
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
7753201
11130063
15611338
32203420
11955434
15967165
8910315
10592173
12393875
11595749
10212259
12829230
|
FYN
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7617039
10804218
16713569
23128389
|
PTK2
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
109.0
|
1.0
|
Omnipath
|
16298995
26053221
15688067
15572663
15592455
7963537
17389395
25405379
26546726
9658172
15107421
22581436
10823820
16254239
25226367
15817476
10330411
9756887
19543320
9054445
10545505
18707149
29127427
15494312
10764815
7537852
9442086
33823745
12408869
20419088
20655620
22270917
18669648
28373581
10455189
16094384
23936270
19138410
22638989
11337490
11514617
27402964
16713569
7615549
10931187
11774284
26700725
27708220
20068231
20473365
28928239
7561682
34475475
28427224
28068967
8922390
24885567
23209645
27669437
15212693
26711338
9422762
11304546
28214467
26697169
12065577
28415719
10753828
11919182
24364863
9230116
11113628
21741599
10417825
15252114
24642576
22044652
21034468
|
DVL2
|
LRP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
PRKCA
|
DVL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12958364
11940581
21386996
11313945
15567848
|
DVL2
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
15262978
12533515
|
PLAU
|
PLG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
18633355
20027185
22470492
27216177
|
PLG
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
12604689
10978167
9020112
|
PLG
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10978167
|
COL5A3
|
SDC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11751872
|
ADAM12
|
SDC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12509413
|
ARNT
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
17213817
8816435
17197389
14764593
12393189
12810720
15319539
23363003
9079689
11829741
15479785
26496610
12391259
17916562
24434214
11606485
20562859
9704006
21620138
11782478
20932347
15347669
8927054
21435239
19168635
9159130
14668441
20049704
20603618
|
RELA
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
12820969
11478739
17510282
19786024
12050170
21138578
12122011
19828633
18367595
22030901
18502824
16707500
10926836
11413310
20663893
22388040
15144466
9120310
12603855
26096887
11259372
21189258
12388374
15972972
11389171
25523420
18525004
|
CREB1
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11413310
12388374
7513046
|
REL
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12820969
17705131
11259372
9120310
20058312
16707500
|
PRKCA
|
CFTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
92316961
15212693
26888287
1377674
|
RUNX2
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23159876
11106645
11331591
24404380
|
CREB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11579131
12417340
15079071
15187187
15279786
15337521
15536066
16007092
16713974
17303408
17550372
17565603
17660363
18590585
19171876
19879327
20144767
23430059
7575488
8383323
9743347
|
CREB1
|
RELA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
21.0
|
1.0
|
ACSN
|
11579131
12417340
15079071
15187187
15279786
15337521
15536066
16007092
16713974
17303408
17550372
17565603
17660363
18590585
19171876
19879327
20144767
23430059
7575488
8383323
9743347
|
CREB1
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
2170405
22357921
8648265
15908479
1845987
8803927
2542772
15608673
1404598
1320003
12372774
|
CYLD
|
DDX58
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18467330
18636086
|
DVL1
|
LRP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
SDC4
|
DVL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23151663
18403410
16604063
|
DVL1
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
15608632
19365405
12533515
17363564
|
LRP6
|
DVL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
F2
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9058715
10978167
15707890
10644723
14652070
11356985
23450633
18250335
12563219
22972936
|
F2
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10978167
1135698510978160
11356985
|
FGF2
|
PLAU
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11874475
18232728
18633355
18776941
19508171
19631971
21098712
22652804
23123598
25374926
9242465
|
HIF1A
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19492421
16399861
17536272
17942638
|
FGF2
|
SDC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9556568
20382221
9012653
8621465
16982797
8609172
|
FGF2
|
SDC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20382221
8621465
16982797
1101561416982790
8609172
11015614
|
FN1
|
PTK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
FN1
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
RELA
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10649441
18064631
10867646
22223884
12372417
|
TNC
|
FN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7499434
20708078
21349332
|
THBS1
|
FN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
19542224
11773026
18042364
18226512
|
FN1
|
SDC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10772816
1077281610772810
|
IL7R
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7515933
16713569
|
FYN
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17145710
25241761
11927579
10383400
8621384
28259175
12721299
18387943
10319993
|
FYN
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
11369622
12558988
15494733
20151426
12590707
16293639
7505391
15728464
11278857
16713569
10753828
15494732
10085136
15494734
|
FYN
|
PRKCQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10383400
16713569
|
RELA
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18498249
17898080
23185316
|
HIF1A
|
TGFB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7539918
8943284
1823643
12829734
9159130
10712429
13130303
11566883
12080085
10403805
9746763
15451019
11790723
9278421
16887934
|
RELA
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
18298869
12105194
11376631
14600595
17673602
23423566
17922642
15605368
14755547
20332461
18357389
21502320
17186550
11060311
18566231
9679762
16554298
16687076
17121934
15086314
18843978
21963718
18056465
20103608
21238464
17174275
15536164
18028425
17158602
17590163
19303700
7860222
19539355
9500201
22587999
19783786
18567920
15175338
17498959
19616091
10359016
18801463
19454280
24755270
19662350
12193473
16014933
|
NHEJ1
|
POLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
Reactome
|
16439204
17470781
22529269
15451442
14561766
12077346
10757784
9259561
16439205
11702069
18046455
9430729
12509254
|
PDPK1
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10652356
11687500
11747822
12670391
15214048
15536066
15802604
16606694
17544292
17548359
17680028
18784374
18802401
19109239
19122654
19201850
23077238
23433459
23474202
23886063
25960930
|
PDPK1
|
PRKCE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
11964154
11062054
10945988
12640464
|
PDPK1
|
PRKCA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15209375
11078882
10698939
9889098
|
PDPK1
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
16505477
21310943
11839738
31511386
9748166
25472878
25755284
15811957
15133032
11781095
19664995
15024053
15302935
15949469
14581488
28784722
17570831
18669648
11381116
20058876
17965192
19632318
20501830
|
PLAU
|
PTK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
11306493
18633355
19833085
21840487
22470492
22595692
27216177
7512720
7521688
|
RELA
|
PLAU
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11689575
20352621
18226221
19165610
22797919
20018891
10467400
9914486
17407600
|
PRKCA
|
RAC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10679481
10871288
16492141
18851840
20027184
21474067
|
PRKCA
|
SDC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9244383
19901323
|
PRKCA
|
PRKD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15212693
18337243
11741879
11948398
17570479
34010649
10197446
10867018
15024053
15383279
|
PRKCA
|
SDC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
9556568
11916978
14670076
12571249
12377772
|
PRKCA
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16628218
20027184
11284700
18851840
21474067
|
PRKCD
|
PRKD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
15212693
11741879
11948398
23109817
21726532
10867018
15024053
15383279
|
PRKCD
|
SDC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9556568
12377772
11916978
16141413
|
PTK2
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20936779
22163037
26816343
29036929
34252134
|
RAC1
|
RSPO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
ACSN
|
11226259
11274345
11756498
12533515
14704854
14747478
15265686
15618519
17127310
17884187
18000759
18497258
18851840
18953287
19020754
19151919
19565474
19853559
20006983
20093472
20215527
21087212
21380625
21796133
22017973
27331412
7641885
8655584
|
RAC1
|
RSPO3
|
â—¼ SHARES_COMPLEX
|
|
|
28.0
|
1.0
|
ACSN
|
11226259
11274345
11756498
12533515
14704854
14747478
15265686
15618519
17127310
17884187
18000759
18497258
18851840
18953287
19020754
19151919
19565474
19853559
20006983
20093472
20215527
21087212
21380625
21796133
22017973
27331412
7641885
8655584
|
RSPO3
|
SDC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
21397842
24275095
|
THBS1
|
SDC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
32196115
17879962
|
POLM
|
SDC4
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.04
|
1.03
|
PKG
|
28854368
|
NHEJ1
|
COL6A1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.06
|
1.05
|
PKG
|
28854368
|
SETX
|
SDC4
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.11
|
1.1
|
PKG
|
28854368
|
RAD18
|
SDC4
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.13
|
1.12
|
PKG
|
28854368
|
NHEJ1
|
SDC2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.31
|
1.31
|
PKG
|
28854368
|
RAD18
|
SDC2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.39
|
1.38
|
PKG
|
28854368
|
NHEJ1
|
FGF2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.54
|
1.54
|
PKG
|
28854368
|
NHEJ1
|
PCNA
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.66
|
1.65
|
PKG
|
28854368
|
SETX
|
FGF2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.71
|
1.7
|
PKG
|
28854368
|
DDB2
|
FGF2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.76
|
1.75
|
PKG
|
28854368
|
RAD18
|
RAD18
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-4.39
|
4.38
|
PKG
|
28854368
|
DDB2
|
DDB2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-5.71
|
5.7
|
PKG
|
28854368
|
NHEJ1
|
NHEJ1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-6.47
|
6.46
|
PKG
|
28854368
|
SETX
|
SETX
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-8.56
|
8.55
|
PKG
|
28854368
|