Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
JUN CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20711235 20697347
THBS1 CCN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18550634 16878133
CXCL8 GNAI1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
GNA14 GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
GNAQ GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
GNA15 GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
CAPNS1 GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GNB2 ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1962211 1312225
F2RL1 CNN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 CLPTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
GNA14 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA14 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
F2RL1 SYNGR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 ABCC8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 ABHD14A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 ADCY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
AREG EGFR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 20430953 23010081
JUN AREG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22570239 20308529
F2RL1 ARL6IP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
MAPK1 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
ARRB1 GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353685
F2RL1 ATP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 ATP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 ATP2C1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 BSG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CAPN1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8695851
CAPN1 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10978167
CAPN2 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10978167
F2RL1 CAPNS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217522 15708858
CBL F2RL1 â—¼   COLOCALIZATION 2.0 0.8 intact 5217522 15708858
F2RL1 CD63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 CD81 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 CRLS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CTSG F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10978167
TLR4 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17126326 5219377
EGFR PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499
ELANE F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10978167
F2RL1 ERGIC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 F3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0606411103 16959886
F2RL1 PTDSS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 KLC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 NBPF15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 SLC35A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 YIPF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 SLC18B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 MORN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 RGR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 P4HTM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 SLC1A4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 QSER1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 NAT14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 TMBIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 OSTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 HERPUD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 SLC39A13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 ICAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 SLC43A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 TMEM62 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 PIGU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 TMEM161A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 TMED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 MFSD10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 HMOX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 HLA-E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 PPM1J â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 PRRT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 GJB6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 GJC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 KDELR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 SCN1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 SLC31A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 RTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 PSMC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 SDHD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 SLC12A5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 RTN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 PRNP â—¼   PROXIMITY 2.0 0.8 intact 28298427 20167430
PRSS1 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9349532 10978167
PRTN3 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10978167
TPSAB1 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21999702 9020112
F2RL1 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9349532 31160049
WFS1 FOSL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNA15 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
JUN PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17138645
CAPN2 CAPNS1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
GNAI3 GNB2 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
EGFR RAB3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
CD81 GNAI3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
CD81 GNAI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
TMED2 TMED1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TMED10 TMED2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RTN4 RTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EGFR CD44 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23265944 12093135 16565089 15597342 11606076
CD81 EGFR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32900848 30024968
CAPN1 CAPNS1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
JUN MAPK1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
GNAI1 GNAI3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR ARRB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
THBS1 PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 6438154 2522013
F2RL1 GNB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8615752 9349532 7937743
EGFR AREG â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28988771 8663535 10085134 16713569
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
COPS5 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16410250
MAPK1 DUSP6 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 17208316 22569528 20463170
F2 F2RL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 873923 8615752 10079109
JUN TPSAB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16730810 15464728 11157480
MAPK1 KLC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21385839
FOSL1 JUN â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
MAPK1 DUSP6 â—¼   PHOSPHORYLATION ✅ - 0.9 0.9 Signor 15632084
DUSP6 MAPK1 â—¼   DEPHOSPHORYLATION ✅ - 0.9 0.9 Signor 12840032
DUSP6 MAPK1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
CAPN2 CAPNS1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
JUN FOSL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11912197 33961781 11431474 11708771 23661758 9160889 24029232 20511396 26258633
TMED10 TMED2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
JUN CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 18684922 16701870 24048734 14686613 24284797 15057743 12643600 17197543 11864912 10817569 12218154 22031759 17586662 10969814 19064995 12716652 27856305 25582859 17471497 22095787 16818736 23176534 14670967 18435575 16846747 19734226 16299055 14612204 18772138 19132242 12209633 15939312 16834785 11399048 11120852 25567680
PLG F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12604689 10978167 9020112
GNAS ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9228084 9395396 1719547 9268375 21406690
PTGS2 AREG â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 18633355 20138012 21847358 23010081 23390297 25987127
AREG EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 23762360 21071413 10209155 10085134 29045902 2466334 20513444 16713569
MAPK1 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
ARRB1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
ARRB1 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
CAPNS1 CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 28319173 10666632 11673052 16597616 10639123 18519038 11517928
MAPK1 CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11319218 14993287 10644690
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
COPS5 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25609649 20093369 18926707 10766246 16713569 8837781
DUSP6 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12840032 23331499 8626780 18060821 8910287 8670865 9596579 14690430 15632084 9922370 17322878
PTGS2 EGFR â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18633355 20138012 21847358 23010081 23390297 25987127
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
TGFB1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20953304 32103204 19132220 28943431
F2 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10978167 1135698510978160 11356985
JUN F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23038262 11057875 20671239 15201277 15636197 7615158 9585253 9081693 8647847 14603525
JUN FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18435914 15806162 13679379 17082637
JUN FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9160889 11708771 23661758 20511396 11431474 24029232 11912197
JUN TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 12759366 11087751 7935377 21059644 16881863 24548427 12509451 9826775 10318823 8998076 18408586 15546613 20164416 7896795 9211933 10952728 9566900 23583459 10748079 24009130 10954918 10754326 9813054 10837498 9988757 11739517 16365438 19285436 16199883 8816436 10551799 8552071 9160673 11490006 21098092 16483936 10688670 10913190 16888805 9030359 25567680 9760243
JUN PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11901151 16001969 19783677 15238218 23523690 10668496 16007171 12057991 22472290 18294142 16339564 17556653 9830045 9988750 19825968 15994313 15772294 9620167 9686761 15525691 11356200 16256955 11234900 18097055 11980644 9705326 19522015 11278336 18282182 12086396 10811116 20237399
JUN TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8058069 16327802 16730810 23437118 8183578 16365456 22429882 23936544 15546613 10843986 16978906 23762330 7521696 8631909 12794825
MAPK1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8072547 11313929 15378002 12531896 12853483 23720779 9662434 1496019 17570479 1922387 11278277 11739718 16023596 20086174 25557171 7737130 26755651 8224842 14676207 17920329 25201974 9022811 22327296 18650425 8137421 18443042 12881422 18572021 17001009 33767435 7744008 23616010 26745678 14617628 11432833 16819515 22606284 12040039
KLF6 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16611854 18615188 9837963 19076057
THBS1 SDC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 32196115 17879962
THBS1 TGFB1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10657674 11982756 14568985 14996710 21900405 22943793 8349738
THBS1 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22943793 8349738 21900405 1550960