Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
F2RL2 F2R â—¼   PROXIMITY 2.0 0.8 intact 17376866 0700763104
PRSS1 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9349532 10978167
F2RL2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GATA2 F2RL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
PRSS1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
PRSS1 MMP3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 3058116 7826345
PIF1 PRSS1 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
EPHA1 PRKDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ERCC6 SNCA â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
LATS1 PARD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26116754 24255178 34079125
KRT1 PRSS1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KRT10 PRSS1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KRT2 PRSS1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KRT10 KRT2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
KRT1 KRT2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
KRT1 KRT10 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PRKDC NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
ERCC6 PRSS1 â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
SMARCAL1 PRSS1 â—¼   KO_DOWN_REGULATES ✅ - -1.22 1.21 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
NHEJ1 PRSS1 â—¼   KO_DOWN_REGULATES ✅ - -1.26 1.25 PKG 28854368
PRKDC PRSS1 â—¼   KO_UP_REGULATES ✅ + 1.42 1.42 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
SMARCAL1 SMARCAL1 â—¼   KO_DOWN_REGULATES ✅ - -7.33 7.32 PKG 28854368