Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MAP3K3 AKAP8L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STK11 CDC37 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 34591612
CDC37 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2R1A CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
RACGAP1 CDK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
RPA2 CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CSNK2A2 PTEN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12297295 11035045
LDOC1 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 MVP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 PSME3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PSMC3 HTRA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTRA2 BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11583623 5214623
YWHAH MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
YWHAQ MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
MYC ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17006931 8076602
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC MYCBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15979100 20562918
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYC MYO1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17353931 17093053
MYO1B MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NUAK1 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
NUAK1 LATS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7717767 19927127
TET2 OGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353889
RACGAP1 PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19468302 1000111
RACGAP1 PLK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 1000110 19468300
YWHAG STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8329523 22575644
YWHAH STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8329523 22575644
STK11 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TUBB6 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SF3B4 CHERP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SF3B4 RBM10 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 22365833 8293266
JUP BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CHERP CCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPH2 RBM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPH2 PRPF31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
KRT17 KRT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ESR1 HEXIM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18757415 21423213
HSP90AB1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CAV1 TRAF2 â—¼   COLOCALIZATION 2.0 0.8 intact 5213300 11112773
SPTAN1 JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PTEN CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12176037 6731969
CAV1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
MAST2 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15951562
PTEN RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10753747
YWHAQ RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
YWHAG RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
RACGAP1 AURKB â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
FBXW5 CUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14603323 5216801
DIABLO BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10929712 5212852
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
HSP90AB1 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SRC CKAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC F2R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
HSP90AB1 LIMK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17188549 16641196
SCRIB MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
WWTR1 LATS2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21205866 18227151
AMOT WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21205866 23431053
ESR1 SIAH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 16141343
TUBB TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAG ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TIMM13 ADRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
ALB YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
RACGAP1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MAP3K2 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG SRRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAG SRRM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG TRA2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MOB1A LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
MOB1B LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
MOB1A LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
MOB1B LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
PPP2R1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2R1A MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PRKAR1A PRKACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 24855271 1252328
PRKACA SLTM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EIF4EBP1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19375531 7021854
HSP90AB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SPTAN1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
PPP1CA MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP1CC MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SPTBN1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAH MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP1R12A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAQ MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SF3B6 SF3B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
WWOX CPSF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217863 16055720
WWOX CPSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217863 16055720
WWOX FIP1L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217863 16055720
CCAR1 RBM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
BIRC2 HTRA2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
YWHAG RACGAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
LATS2 SAV1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
SF3B1 SRRM1 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
STK4 CDC37 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24366813 23455922
CDC37 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17525741 25036637
MYC CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
CDK2 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
ESR1 DDX50 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21182205 31527615
RAF1 EMD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 25852190
HTRA2 LATS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17130845 22641346 16007220
HTRA2 PSME3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31617661 33961781
SF3B1 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29467282 20936779
MYC CPSF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 20551172
MYC NOP58 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC PKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25609649 29467282
MYC RING1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
OGT TET2 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
ESR1 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
SRRM2 SF3B4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
AURKB DPM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29568061 31586073
TRAF1 CUL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
YWHAG MAP3K2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5217174 15324660
SAV1 AMOT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30266805 24255178
SVIL ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 11792840
ESR1 OTUD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ESR1 MYH14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21182205 25604459
PARD3 AMOT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 16678097
TRA2A SRRM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ZYX CCAR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STK3 MOB1B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 21808241
CDC37 RAF1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
MYC DPM1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
MYC PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 30415952 29467282
STK4 RASSF1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
RPA2 ESR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11953755 31527615
FBXW5 CUL4A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22910413 17079684 18381890
MAX RING1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 24981860 27705803
MAX PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 22325352 33961781 25609649 24981860 29028833 20946988
CREBBP HIST1H4A â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
CREBBP HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
WWTR1 AMOT â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20972459 33961781 26186194
TRAF1 OTUD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 25996949
MOB1B MOB1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 24366813 33961781
LATS1 PARD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 26116754 24255178
TRA2A SRRM1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SRRM1 SPOP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29996942 31911863 28805822 21988832
PSME3 PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PTPN14 WWC1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
NOP2 NOP58 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
LATS1 STK4 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
NUAK1 SRRM2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
STK3 PLK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20562859 24255178 27566175
SRC TRAF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10635328 15707590
LATS2 AMOT â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24225952 24101513 24106267 24255178 30266805
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HIST1H2AJ HIST1H4A â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
MDM4 YWHAQ â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
MOB1B STK3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H2AC HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
AMOT NF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
SIAH2 TRAF2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12411493 16713569
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
LATS2 USP9X â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 29183995 28720576 24255178
LATS2 LATS1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 24255178 34079125 32707033 21233212
LATS1 STK4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24012335 15688006 33945069
NF2 AMOT â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
MYC MYO1B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 29467282
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
RAC1 BIRC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24276241 25301945 22117219
WWTR1 LATS1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20412773 27847303 29787761 26116754 22078877 21555462
RACGAP1 KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 8397056 22580824
CUL1 CDK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 9636170 26186194 21145461 23455922
TRAF2 HTRA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20562859 31617661 33961781 33229071
MYC TAF12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 30415952 12660246
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
SF3B1 SF3B4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28541300 12234937 22939629 26344197
SF3B4 RBM10 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 22365833 26871637
PTEN MAST2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15951562 22894835
SIAH2 LATS2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27030211 25438054
YWHAG KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5217174 15324660
STK4 MAP1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20562859 23455922 24366813
STK3 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 23431053
STK3 STK4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CKAP5 SLAIN2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
LATS2 MOB1B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CAV1 RAC1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ARHGEF7 SCRIB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ARHGEF7 RAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
BIRC2 TRAF2 â—¼   UBIQUITINATION ✅ - 0.87 0.87 Signor 20651737
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
RAF1 CDC37 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25036637 31980649 24189400 24292678 17979178 33961781 32707033 16611982 16335536
CDC37 AURKB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25036637 33961781 26186194 31586073 32707033 29568061
OTUD4 FXR2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29395067 19615732
MYC PLK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27773673 17314511 33494392 29467282 30415952
PKP1 DSG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9606214 24981860 19136012
TRAF2 CAV1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11805080 16189514 16713569 11112773 32041822
CUL1 FBXW5 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
LATS2 MOB1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23886938 29183995 19739119 20624913 33961781 24255178 31941533 26898830
LATS2 MOB1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 19739119 33961781 24255178 32707033 19919647
LATS1 MOB1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16061636 16674920 33141042 19739119 20624913 24255178 31941533
STK3 MAP1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 24366813 23455922
MOB1B LATS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 16674920 19739119 33961781 24255178 34079125 24366813 18328708
AMOT LATS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 30266805 32292505 24101513 24255178 34079125 24366813
STK4 MOB1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22863277 24255178
SRRM1 SRRM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16159877 9531537 22939629 26344197
SF3B4 SRRM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MDM4 YWHAG â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
BIRC2 TRAF1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
SF3B1 SRRM2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RAF1 YWHAH â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AJUBA LATS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20303269 33961781 16413547
CDK1 LATS1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9988268 12372621 25218637
PTEN SPOP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24656772 27622336 32297747
RAF1 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
FBXW5 CUL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23314863 23319600 25515538 29103612 25143387 14603323 21145461
SRC CAV1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8910575 8632005 8621645 29720121
KIF23 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
SAV1 LATS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25670202 34404733 25692647 24255178 30266805
STK3 MOB1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18362890 31941533 24255178 23972470
STK3 MOB1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24255178 32296183 19919647
LATS1 ZYX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10831611 16713569
RING1 PCGF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 22493164 12167161 27705803 22325352 33961781 24981860
OTUD4 MYCBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29395067 19615732 33961781
BIRC2 DIABLO â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 12525502
L3MBTL2 PCGF6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
STK4 SAV1 â—¼   UP_REGULATES ✅ + 0.89 0.89 Signor 16930133
KRT16 KRT5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
LATS1 WWTR1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PPHLN1 CDC37 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDC37 STK11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25036637 14676191 20562859 12489981 21860411 33961781 14668798 32707033
CDC37 SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 33961781 31980649 11085988
MAX GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15021909
HTRA2 BIRC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 16713569 11604410 12865429 33961781 11583623 31617661
MYCBP MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9797456 32140074 12223483
MYC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 9315742 28628118 28205554
MYC EXOSC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10918582 18444242 11258956
MYC CLNS1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SFXN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC EIF4B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC PKP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
NUAK1 USP9X â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 16306228 24785407 18254724
PPP1R12A PLK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 18477460 22641346 22365832
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
TAF12 TAF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14580349 23292512 33961781 10594036 15601843 11564872 12237304
PPP1CA CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 4092695
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
TRAF1 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10544141 25241761 20385093 14557256 21903422 14743216 32296183 29748372 11181075 15383523 8702708 8069916 19287455 16713569 9718306 25996949 9500555 33961781
SRC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17097642 16189514 7517401 8876196 10205168
RAF1 STK3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20086174 24929361 15618521 17889669 20212043
PPP1CA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7604263 16630891
SPOP CUL3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22911784 21577200 21988832 19256485 28216678 29160310 25011449 30244836 16524876 22013077 22632832 33961781 25278611 19261606 31559706
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
SRC PPP2R1A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
SCRIB ARHGEF7 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 15975580 5217786
SCRIB ARHGEF7 â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 24550280
CAV1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11563984 23634843 22230296 19595769
ESR1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12138116 18414489
BIRC2 TRAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11907583 16713569 21988832 20447407 9384571 8943045 25996949 33961781 23524849 16891304 30561431 8548810 21903422
SAV1 STK3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 32296183 21988832 15688006 20920251 20562859 16930133 33961781 24255178 26186194 24981860 17379520 23455922 24366813
NF2 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26045165 24012335
MOB1A STK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23386615 24255178 21516123 31941533
STK4 STK3 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
STK3 STK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 28628118 20562859 20920251 24981860 23386615 24255178 28205554 24366813 23455922 26344197
NF2 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26045165 24012335
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PPP1CC PPP1R13B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PPP1CA PPP1R13B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PRPF31 SF3B4 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
RAF1 YWHAQ â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
KRT16 KRT6C â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRT16 KRT6A â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
STK4 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 21808241
PCGF6 RING1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
BIRC2 DIABLO â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
NOP2 RSL1D1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
BIRC2 TRAF2 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
YWHAH RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8005785 11697890
LATS2 STK4 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 30865227 24255178 26578655 30266805 26898830
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
LATS2 STK4 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
PPP1R13B PPP1CA â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 21998301 270751 8217559
RAC1 CAV1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 24625804 27250250 22614015 20460433 31871319 15976327
LATS2 STK3 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
FTSJ3 NOP2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
RASSF1 STK4 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
RASSF1 STK3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MAST2 PTEN â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
SRRM1 SRRM2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
STK4 SAV1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
CPSF1 CPSF2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 24981860 29395067 22939629 33469008 26344197
LATS2 MOB1A â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
MOB1A STK4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
PTEN SPOP â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
SF3B4 SF3B6 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
STK3 SAV1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
LATS1 STK3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
LATS2 NF2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
NOP58 RSL1D1 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
CPSF2 FIP1L1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
MOB1A STK3 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
PRKACA PRKAR1A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
TRAF2 BIRC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25241761 10753917 21988832 19506082 9384571 8943045 19584093 16263936 21903422 32296183 11181075 19815541 20562859 8643514 15861135 16891304 16282325 30561431 8548810 30359437 11907583 20184394 21331077 25716317 25882049 23524849 27534557 25681446 21653699 16713569 20447407 23007157 20348096 33961781 24276241
SAV1 STK4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 30266805 20562859 20920251 25692647 17517604 16930133 23386615 24255178 26186194 27173435 33961781 24366813 24981860 23455922
SPTAN1 SPTBN1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PRPF31 SF3B1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CPSF1 FIP1L1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
SAV1 STK4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
LATS1 MOB1A â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
LATS1 MOB1B â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
SAV1 STK3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
FTSJ3 NOP58 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
TRAF1 TRAF2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
ADRM1 PSMC3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
SF3B1 SF3B4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ADRM1 PSMC4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 PPP2R1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
KIF23 RACGAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL3 SPOP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SF3B1 SF3B6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CPSF1 CPSF2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMC3 PSMC4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MAX MYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CSNK2A2 CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20068231 15082798 19413330 12930845
CDK1 GADD45A â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17660363 18414028 18543256 18590585 18995830 19004803 19652693 19686080 23485469 7575488
CDK1 GADD45A â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17660363 18414028 18543256 18590585 18995830 19004803 19652693 19686080 23485469 7575488
CDK1 RPA2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
CDK1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
GADD45A CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18942077 10362260 10973963 12124778 16189514
CDK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12202491 17145710 17274640 22367880 18088087 17202132 9122166 97225924 10880350
CDK1 KIF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26615533 19007248 16565220 19691289 19001501 28487562 19664994 20068231 16455663 25660025 19690332 8548803 21522128 19413330 9235942 20068230
CDK1 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17145710 12372621 25482410 18691976 25218637 23985307 15688006 9988268
CDK1 CDC26 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 15279786 15917306
CDK1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15735705
CDK1 RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 9139719 17303408 9295339 19793801 15279786 7575488 20068231 17116885 19671522 17582221 26237679 18590585 1318195 22977173 17660363 20932174 17296725 17102137 21664290
CDK1 EIF4EBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11691836 27402756 11553333 17570479 12588975 29610153
CDK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17764786 17660363 15279786 15917306
MYC CDK2 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
MYC CDK2 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
CDK2 RPA2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 SF3B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15212693 12105215 17081983 30115685
CDK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8386367 27653698 17081983 19966300 18669648 29896817 17570479 20713526 17558397 15103331 22348395 20445224
CDK2 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12202491 17145710 14715909 17274640 16550609 18088087 17570479 9122166 97225924 15212693 10880350
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CDK2 PRKAR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 15572359 19007248 17081983 20166139 18767875 19562805 19413330 19415658 20068231 18452278 16582606 25605337 18669648 18691976 17287340 19651622 20058876 19664994 18707149 18212344
CSNK2A2 EIF4EBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 11146653 12588975 18212344 9806882
CSNK2A2 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17444818 19662498 15987703 16107342 11035045 12077256 11707428 12297295
SRC EMD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 25008017 24609268 19789182 29684168 24365856 17637040
MYC GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15721278 9190899 10913183 15021909 14519204 9811446 21835778
HTRA2 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11604410 12865429 11606597 16713569 11583623
MYC MAX â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16596619 21988832 10229200 17471507 26267534 15572685 18003922 20382893 35140242 17418410 25609649 16352593 31767764 17072308 17289033 10918583 9528857 14749374 21807113 19623651 18620061 25522242 32296183 16140957 16705173 19578763 26496610 12584560 17157259 17643117 24951594 20946988 10465786 12706874 12821782 9184233 17353931 10611234 32140074 8266081 20691906 16410719 21150319 10593926 12660246 27859590 12553908 8224841 10319872 2006410 16287840 16606833 23816886 9708738 17314511 9886493 27705803 33298911 33961781 20936779 12824180 9680483 17700062 29467282 30415952 12391307
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
MYC MAX â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7739536 10931841 11673469 10657901 12177005 14519204 9111322 9811896 10567564 17706770 24771621 11983916
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC IGF2BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21779431 18414489 21252116
MYC MAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508165 15665468 8385351 8649388 8521822 22384171 1406956 17341548
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
MYCBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12223483 9797456 20562918
MAX MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 17145710 16287840 25609649 12821782 16606833 16596619 21807113 25522242 20691906 19578763 24951594 8224841 17643117 9528857 12391307 16705173 21150319 10229200 21988832 15572685 9680483 2006410 17314511 14749374 12553908 17289033 17418410 19623651 12824180 17157259 12584560 26496610 20946988 20936779 8425218 23816886 17353931 10319872 17471507 18003922 16140957 20382893 12660246 8266081 7565735 32296183 10465786 26267534 17072308 27705803 9184233 18620061 10918583 17700062 10593926 10611234 16352593 9708738
STK11 NUAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14976552 19369195 21317932 20354225 16488889 29566768
NUAK1 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17739896 24171924 22516431 18088087 19367720 19690332 20354225 19413330 18669648 29106388
NUAK1 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 19369195 18691976 19927127 19690332 19413330 18669648
PLK1 RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 28692064 17081983 16565220 27453045 19007248 19468300 25486482 19468302 19690332
PLK1 CDC26 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19686080 19270156 18931676 19622404
AURKB RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19887622 19276349
RASSF1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17379520 24366813 26186194 14729613 22195963 24255178 20920251 21808241 21199877 19962312 20086174 32296183 17598981 29063833 18347058 17889669 23455922
RASSF1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 20562859 17145710 24366813 26186194 14729613 26578655 24255178 20920251 22683405 15109305 23386615 17598981 21808241 23455922
RPA2 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PRKACA STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11853558 17482548 11297520 17482549 10642527
STK11 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 25763354 17875968 15987703 16107342 11035045 12077256 18321849 23379765 21779440 12297295 25336918
STK11 NUAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18083107 14976552 17242355
TAF12 TAF4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
PRKACA CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 19651622 17081983 1359877 18767875 17322306 18691976 4092695 19664994 20068231 18707149 23429703 11986331 17206380 14991569 19664995 18669648 33771897
SRC JUP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8081883 14517306 23911551
TRAF2 TRAF1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF1 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
TRAF2 TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 14743216
TRAF2 MAP4K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9712898 16713569
TRAF2 TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
TRAF2 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 21653699 25681446 8943045 8643514 11907583 16713569 20184394 18621737 18997794 21988832 25882049 9384571 21903422 16891304 10753917 20447407 18981220 16189514 15861135 11181075 20348096 20562859 25241761 19584093 32296183 21331077 23007157 16282325 19506082 25716317 23524849 24276241 16263936 12887920 8548810 19815541
SRC PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24830552 22891331 12869565 21532586
RAF1 PPP1CC â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
PRKACA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19007248 11971957 20166139 18767875 20230923 9001246 10576742 23331499 20068231 7935389 18669648 18691976 9922370 15664191 19651622 12801936 9091312 10862777 9710607 11997508
YWHAH RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12801936 11697890 8702721 17979178
YWHAQ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 14688280 7760835 17353931 16041367 11697890
SRC RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7692235 12551923 7517401 17097642 15258589 9689060 16189514 16630891 10998357 11376654 29063113 8876196 10205168 28846113 12952943 22592532 11134016 15710605 16170185
RAF1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24929361 15618521
RAF1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17353931 11697890 8702721 10433554 16189514 15664191
RAF1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 14688280 7760835 17353931 16041367 11697890
AURKB RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15630414 14744859 19007248 17178910 19555392 18201571 17287340 12689593 15108802 18669648
AURKB KIF23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15630414 30728176 16461284 25512391 19203582 15854913 20451386
SPOP CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21988832 23331499 19256485 28216678 21577200 25011449 34599168 22911784 15897469 22013077 16524876 19261606 25278611
DIABLO BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 18022362 11606597 10929712 12218061 12865429 10929711 19153467 27476169 14960576 25246529 12525502 20957035 18485876 16282325 19506082 25065467 18022363
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
ARHGEF7 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 24792722 16983070 18684957 16492808 9659915 10592173 14557270 11309380
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
SRC WWOX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 32185845 26120275 31752354 25441426 19366691 16115915 16288044 18371080 27551439 27845895 25650666 31315632 12514174 15070730 15664696
SRC HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17855507
SRC SPTAN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12446661 11971983
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
LATS1 WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23026745 22078877 20412773 22658639 33086783 24550007 21808241 29787761 34022224 20594350
LATS2 WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22658639 18227151 21808241
ESR1 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11773442 17535799 15033483 22031296 15496458
LATS2 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21118956 25086053
YWHAG YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17085597 21827211 12426317 15324660 15071501 12657644
SAV1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20562859 21988832 17379520 24366813 16930133 26186194 17145710 24255178 20920251 21084559 15688006 32296183 29063833 23455922
SAV1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 17145710 24366813 16930133 26186194 24255178 20920251 21084559 23386615 25692647 17517604 23455922
STK4 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 26898830 26578655 24255178 23431053 21808241
STK3 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26898830 21832154 15688006 23431053 21808241
STK4 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24255178 23386615 23431053 21808241 18328708
STK3 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23972470 18362890 23431053 21808241 32513747 30038061
STK3 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19878874 32296183 23431053 21808241 18328708 19919647
STK3 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22195963 29970086 19962312 15688006 30038061
NUAK2 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19369195 18691976 19927127 19690332 19413330 18669648
STK4 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15688006
LATS1 ZYX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10831611 16713569
PRKAR1A PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17145710 15655353 17353931 26687711 11834733 24855271 32296183 24700472 9405392 25477193
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
PRKACA NF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 15743831 33058421 22516197 18071304 17175165 16652148 16267393 18835652 11703924 15378014 17566081 27285107 14724586 14981079 11719502 25925953 17998937 11782491 26997273
PRKACA SPTBN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9798950 20166139 20068231 18669648 17088250
STK4 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18328708 22863277 23431053 21808241
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
NF2 AMOT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19615732 24366813 26045165 21481793 26549023 23414517
DCAF1 NF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24912773 21750658 20178741 26549023 18332868
DMPK PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 11931630 11384979 18669648 18767875 11287000 12220642 18077418 12563012 16713569 12919947 10601309 12600888 18212344
PPP1R12A MYH14 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626