Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MAP3K21 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23319808
PRAG1 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
MAP3K20 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
GIT1 ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218539 16628223
VIRMA YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAB ALS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
ANKS1A YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HRAS ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 34591642
ARAF MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18039929
ARAF MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18039929
YWHAZ ARHGAP21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SFN ARHGAP21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN ARHGAP32 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
YWHAZ ARHGEF16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAG ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MAPK3 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK1 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
PTH1R ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 12220636
GRB2 BAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAP2K1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15994315 15121878
YWHAG BAIAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
BAIAP2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19933840 8009399
BECN1 PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TNFAIP3 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20501938
YWHAG C1QBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
C1QBP YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
C1QBP MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YES1 CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8981370 20489731
YWHAE CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
SFN CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
YWHAG CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
FGR CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12435267 7721825
PIN1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 9499405
YWHAB CDC25A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220486 7644510
YWHAZ CDC25A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CDC25A MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15672448
PPP2R1A CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
CDK1 SFN â—¼   COLOCALIZATION 2.0 0.8 intact 5211905 10524633
MAPK1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17205132
PIN1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11774038 16713569
CDK1 PKN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 31981797
YWHAZ CDK17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CDK17 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MPRIP CENPJ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CENPJ YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16516142 8007368
CENPJ PLK4 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 20531387 7994481
YWHAB CHEK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20639859 8010047
CHEK1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20639859 8010047
CHEK1 MDM4 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218401 16511572
CLK2 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CLK3 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CSNK1A1 YWHAZ â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 12062430 5215475
GRB2 CYTH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
YWHAB DACT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 21262972 9069260
DCAF7 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
DENND4A YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAB DENND4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG DENND4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
EIF4E2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAG EPB41L3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
EPB41L3 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
RASSF8 ERC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAG ERC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
FGR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10329689 23109003
NR3C1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16303956 3611064
PPP2R1A FOXO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20110348 8288835
YWHAZ FOXO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10102273 5211323
FOXO3 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10102273 14701673
NR3C1 FOXO3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22848740
FOXO3 PIK3C3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11278373 18388194
FOXO3 TSC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20371605
YWHAQ FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10102273
YWHAB FRMD6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
FRMD6 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PIK3CA GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31066629 23246379
GRB10 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
KLF15 GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15963234 15277472
PRICKLE3 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RIMS2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PPP2R1A GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
KLF15 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIK3CA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 PPP1R12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBA1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBB4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MPRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 SRSF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
YWHAE HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10737771 5212359
HRAS KLC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17138645
SOS1 IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
YWHAZ IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
IRS2 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
IRS2 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MAPK3 IRS2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
IRS2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11505033 15705774
YWHAG KIF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
KLC3 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
NR3C1 KLF15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20956975 23508109
PPP2R2A KSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15664191
KSR1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9115393 9858547
YWHAQ LARP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
LARP1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
LARP1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
LARP1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MOB1A LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
LBR YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
LBR YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SFN MAGI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
SFN MAP3K2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
MAP3K2 YWHAE â—¼   COLOCALIZATION 2.0 0.8 intact 9452471 5221876
WNK1 MAP3K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14681216
YWHAE MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAQ MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAG MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAH MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP1R12A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MPRIP MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAB MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2R1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
WNK1 MAP3K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14681216
PPP2CA MAP3K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20448038
MAPK1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK3 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK3 SOS1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
SFN MAPKAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
YWHAQ MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
YWHAB MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
YWHAH MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
YWHAE MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
SFN MPRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
YWHAZ MPRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MPRIP YWHAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MPRIP YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MPRIP YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
NF1 NRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 2116237 2121370
YWHAH NRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213764 11266503
NRIP1 YWHAH â—¼   COLOCALIZATION 2.0 0.8 intact 5213764 11266503
RASSF2 OPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ PANK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PRKCI PARD6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213720 11257119
PRKCZ PARD6A â—¼   COLOCALIZATION 2.0 0.8 intact 17057644 5219258
PRKCZ PARD6G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
SFN PDZD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SHC1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7537361
PIN1 PTOV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAZ PKP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216636 12941695
SFN PLK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PLK4 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PPP2R1A PPFIA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
SFN PPFIBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
YWHAZ PPP1R12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8008120 18094049
PPP2R2A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1328247 19114990
YWHAZ PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10620507
PTH1R YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12595070 5216147
PTH1R YWHAH â—¼   COLOCALIZATION 2.0 0.8 intact 12595070 5216147
SFN PTOV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
RABGEF1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
RABGEF1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
RASSF8 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SFN RHPN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
YWHAZ SAMD4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SIPA1L3 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
USP43 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN SHROOM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SOS1 SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9544989 6547749
SIPA1L3 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAG SRSF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SRSF10 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TBC1D1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG TSC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAZ TUBA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG TUBA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB TUBA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TUBA1B YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ WWC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
YWHAQ CBL â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8005785 11697890
YWHAB EPB41L3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
YWHAB MAP3K2 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
YWHAQ MPRIP â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
N4BP3 NEDD4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11717310
SFN SOS1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CBL YWHAB â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
ALS2 NEK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOS1 BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 8112292 7529874
C1QBP LBR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 28565870
CDK14 FGR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CLK2 NKTR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
YWHAG MAP3K2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5217174 15324660
PPP2CA PPFIA1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 27880917
SIK1 SIK3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BAIAP2 YWHAQ â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
TUBA1A VASH2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
TUBA1B VASH2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CDK1 CDC25A â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 12411508
CDC25A CDK1 â—¼   DEPHOSPHORYLATION ✅ + 0.82 0.82 Signor 10454565
KRAS MAPK1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SOS1 YWHAZ â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
SOS1 KRAS â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 25624485
CBL BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20675402 8621719 14725908 8641358 19380743
CBL FGR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 7721825 12435267
CDK1 CDK17 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDK14 CDK17 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CLK3 CLK2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8153045 21516116
YWHAG FRMD6 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217174 15324660
PTPN14 WWC1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ARAF YWHAZ â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
NHSL2 YWHAG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
MAPK3 RPS6KA2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
BAD SFN â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST1H3A YWHAZ â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
FOXO3 YWHAE â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CCNB1 CDK7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 26186194 11113184
CLK3 LBR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23602568 32707033
CLK3 LARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23602568 32707033
KIF1B MAGI1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29395067 12097473
FRMD6 RASSF8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
MDM4 YWHAQ â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
TUBA1B TUBB4B â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ARAF KRAS â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
ARHGEF6 GIT1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
BECN1 NEDD4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21936852 29251248 28128446
IRS4 GRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9553137 21706016
C1QBP PRKCZ â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
MAPK1 SHC1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CENPJ TUBA1B â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
GRB2 GIT1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21900206 21706016 31980649
NHSL2 ABI2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32296183
ARAF HRAS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SFN BAD â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 20005908 8009659
CSNK1A1 MDM4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PRKCZ PARD6A â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5219258 17057644
PARD6A PRKCZ â—¼   COLOCALIZATION ✅ 0.87 0.87 mint 5219258 17057644
HRAS PIK3CA â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
GRB2 PTK2B â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BAD YWHAQ â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HRAS NF1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TUBB3 TUBB4B â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CBL YWHAQ â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
YWHAE YWHAG â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
YWHAZ ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8009399 19933840
TAB3 BECN1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21976705 22081109
BECN1 TSC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 20562859
BCR GRB2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CLK2 CLK3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MDM4 YWHAG â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPP2CA PPP2R2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CBL SHC1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC5 YWHAE â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
YWHAZ BAD â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 1204662 8005727 11526496
HDAC5 YWHAQ â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CBL MST1R â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
GIT1 NEK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CHEK1 PABIR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 33108758
YWHAG ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
YWHAB BAD â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8929531 10597268 12566304
MAPK3 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19777442 10597268 12566304
MAPK1 BAIAP2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
MAPK3 BAIAP2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
CBL PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CBL PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
FN1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18624398 19738201
FOXO3 PIK3CA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19299143 18644865
MAPK3 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19282669
SHC1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18385518 15930121
PTK2B GRB2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10679059 12626562 9763606
IRS2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19109239 7890616 9535722
IRS4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9553137 15316024
IFIH1 TBK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
SOS1 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25624485 23331499 16293107
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAP3K2 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11343802 23331499
MAPK1 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP3K3 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
MAP3K3 MAPK1 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
PPP2CA MAP3K7 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 608155200 17079228 8204431
MAPK1 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
PPP2CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK1 TSC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15851026 17671177
MAPK3 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
PPP2CA MAPK3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15930121
TBK1 OPTN â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 18307994 6492190
SHC1 PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CA SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
PRKCZ PIN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
YWHAB PRKCZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PTK2B SHC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10679059 12626562 9763606
YWHAG SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
YWHAZ SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
SFN YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
SFN YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
TNFAIP3 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18353649 15661910
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
BAD YWHAZ â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
SOS1 HRAS â—¼   GTPASE_REACTION ✅ + 0.9 0.9 Signor 23132018
GRB2 SOS1 â—¼   RELOCALIZATION ✅ + 0.9 0.9 Signor 23452850
MAPK1 RPS6KA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PPP2R2A PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20711181 8288198
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
SHC1 SOS1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
PPP2R2A PPP2R2B â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
GRB2 BCR â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5214841 11726515
NEDD4 GRB10 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 12697834 10446181 15060076
ARHGEF7 GIT1 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
MAP2K2 MAPK3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
ARAF MAP2K2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ARAF MAP2K1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
FOXO3 YWHAZ â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PARD6G PRKCI â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
KSR2 MAP2K1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
SYNJ2 GRB2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 9388224 20936779 17474147
SOS1 HRAS â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 17084389 5219305
PARD6A PRKCZ â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PARD6B PRKCZ â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TUBA1A TUBA1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
LATS2 MOB1A â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
PARD6G PRKCZ â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
PPP2R1A PPP2R2B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
PPP2R2A PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17245430 5219546
SHC1 CBL â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 9234717 9541596 15677445 8621719 16713569 8950973 10025673 10570290 8662998 19380743 9461587 9434624
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
CDC25A CHEK1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
GRB10 NEDD4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CCNB1 FZR1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PARD6B PRKCI â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
PARD6A PRKCI â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
OPTN TBK1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
KSR1 MAP2K1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
MAP2K2 MAPK1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
HRAS SOS1 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12213123 8491186 8950973 9927207 9733714 8112292 10356320 11370743 32062451 8294403 16371368 22057045 9045692 9032244 8995379 7514169 9175774 9541596 8663178 7629070 9019162 7597091 7798267 9544989 9488479 8940013 10570290 15812354 11792427 8621719 24430869 7650032 11453982 16713569 7516467 10477741 8662733 11302736 26551075 9254595 7559490 12441060 8662998 8235613 12485888 28690151 16520382 8939605 11505033 9129019 11707405 15888547 8647288 7524086 25416956 24189400 11827484 12149229 8195171 21725358 9020193 10049786 9797459 9886492 33961781 9126968 8626525 7537740 12577067 11964172 12898421 8810340 22974441 19380743 9434624 10080542 9083103 21706016 15688026 7535773 31980649 8561895 7744881
PPFIA1 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPFIA1 PPP2R1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A PPP2R2A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GRB2 SOS1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PAK5 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 28007610 10880354 15226424 10521512 15972258 23162742 9381178 12897128 20567954 16403219 15037618 10837486
ARHGEF6 GIT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10428811 10896954 10592173 16373173 21900206
ARHGEF7 GIT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10428811 21295525 12473661 10896954 16628223 16787945 10592173 12695502
KRAS ARAF â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 24937142 16537381 16364920 19727074 11325826 16508002 23360980 15467451 23993095 15258589
YWHAG ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17353931 15324660
YWHAZ ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19933840 20936779 25852190 20052757
HRAS ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 12620389 24441586 21779497 10545207
YWHAE ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19608861 20936779 25852190 17979178
ARAF MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18039929 8131746 8394352 24114843 15175348 15466476 94178255 7936666 7731720 7873542 7624324 8157000 8039496 8621729
ARAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 21988832 18039929 24746704 16189514 32296183 25852190 21779497 11909642
CBL ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23175185 12935897 16407834 22588125 14505571
ARHGEF7 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 23175185 12935897 16407834 22588125 14505571
MAPK3 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
PPP2CA ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
MAPK1 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
CDK1 BAD â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12049737 14551205 15279786 17303408 17660363 18414028 18590585 21725609 7575488
RPS6KA2 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 55.0 1.0 Omnipath 11983683 10880354 20166139 9346240 11493700 9381178 15037618 15280015 10230394 10558990 8929531 19641507 18669648 10837486 10611223 15226424 12954615 10521512 10949026 15972258 18707149 12897128 19282669 16403219 17270021
YWHAQ BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 21988832 15694340 11697890 8929531 16713569 9369453 15280438
PRKCI BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21419810 15705582
YWHAH BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21988832 11697890 8929531 9369453 17979178
CDK1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 18071308 16166315 24677263 12965220 15907327 26287183 21858202 25618528 12049737 16009721 19124971 16403219 17498878
BCR PIK3CA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15050920 20226962 11689702 11739186 15448205
BCR YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17081983 18669648 18691976 20068231 9360956 16045749 98030561 19664995 19415658
BECN1 PIK3C3 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 PIK3C3 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 PIK3C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 18628207 36042481 19713971 19050071 16179260 25594178 21936852 18843052 24980959 28128446 25906440 26496610 26783301 23954414 19379691 23332761 20562859 23974797 24034250 16390869 24980960 19270696 25825496 19172397 20711182 23315026 25490155 24472739 17438366 23364696
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
PTK2B CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11149930 15128873 16713569
YES1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10092522 11994282 11997497 12522270 9525940 12604776 9890970 9102067 10829062 10799548 11239464 10934191
CBL PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8641358 9119889 19380743 8621719 7629144 17635922 10514377
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
CDK1 CDC25A â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 1075565 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17568790 17596790 17660363 18073536 18414028 18543256 18590585 18786381 18995830 19652693 19686080 7575488 9892021
CHEK1 CDC25A â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17568790 17582221 18677104 19793801 20126263
CDK1 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17303408 18073536 1075565 19413330 15279786 7575488 17172867 17570479 12411508 18167338 27580187 18927152 19652693 18590585 12124778 18786381 17660363 21379580 15917306 22263797 27038604 17568790
CSNK1A1 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 19734889 20348946 29725502 14681206 29793495 21252624
CHEK1 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 75.0 1.0 Omnipath 12676583 22040655 29435105 12759351 14681206 18677104 20860841 15798197 19793801 22655267 12963847 16682204 14752276 16647857 15736430 29725502 17116885 17582221 20126263 16697662 18167338 19075565 9278511 18480045 17384638 21148633 21252624 27493659 12110582 17030123 23335075 20068082 11298456 27908669 27213455 25936524 15459660 28150240 20798862 22263797 27038604 17296725 14559997 12399544 17102137 17568790 16488126
CDK7 CDK1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
CDK1 TSC1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 14551205 15279786 17303408 17660363 18414028 18590585 7575488
CDK7 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 85.0 1.0 Omnipath 16565220 18767875 11113184 33657372 27303922 19690332 19667075 15703371 10913154 14988404 1532335 29793495 20360007 7799941 19158392 19664995 33574676 19809470 8548828 7533895 17386261 34489572 26881937 17554681 20068231 18452278 21900495 18669648 12814430 16327805 18691976 15868411 8441405 21778139 25849598 27908669 12459251 1833185 19651622 22263797 19847258 19707596 17924679 20347419 29435156 18220336 34370741 19369195 22505032 21468563 17884153 12663041 22425727 7944411 12648680 11900249 8344251 16697054 31429764 24970150
CDK1 PIK3C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20513426 26432751 28409123 27680387 28858266 26108642
CDK1 TSC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 11444800 14551205 18414028 20006582
CDK1 LBR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 14718546 9045635 17570479 20576617 21795390
CDK1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15735705
CDK1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 20798862 19837665 18691976 21765472 21907702 29092815 18983824 16629900 22686412 24242917
CDK1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25971971 8114697 11684694 17570479 12609978
PLK4 CENPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20531387
PPP2CA CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11390642 17015476
CHEK1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 16163388 16511572 18356162 17110929
SIK1 CRTC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19244510 17525332 18669648 16817901
CSNK1A1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 28695147 17081983 18669648 18691976 20068231 19860830 9360956 16045749 98030561 19664995 19415658
CSNK1A1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20110348 19188143
CSNK1A1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 14613942 19651622 17081983 15119949 18691976 20068231 18452278 9360956 16045749 12062430 18077418 19415658
CSNK1A1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23028042 33667384 31462704 16511560 29793495 16024788 27114532
CSNK1D YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9360956 16045749 17081983 98030561
CSNK1G1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9360956 16045749 17081983 98030561
CSNK1G2 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9360956 16045749 17081983 98030561
CSNK1G3 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9360956 16045749 17081983 98030561
FGR PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23109003 12495636 7529876 10593973
FN1 SHC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19342448 21844907 10714768 8598224
PPP2CA FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19029949 15207915 20110348 17322870
MAPK1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18204439 29445193 22128155 10102273
FOXO3 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18644865 10783894 16288288 20673124 11094066 17646672 15509806 11994454 11154281
MAPK1 GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15952796 18220336 18669648 20068231
MAPK3 GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15952796 18669648 18220336
GRB10 NEDD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12697834 23331499 10446181
SOS1 GRB2 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 8810325 33961781 8695800 7510700 8626525 34407391 16520382 10570290 16906159 16893902 7642581 8816480 9447984 12577067 11964172 8112292 8493579 7664271 16713569 7516467 19380743 9009162 10207103 17474147 10477741 32062451 7629138 21706016 20473329 19323566 9872323 32203420 7514169 21988832 28166272 28514442 9716598 11997436 9344843 15192046 10716926 8479541 14679214 8943292 31980649 7629168 7559490 9478994 7527391 8188688 11960376 10025673 11726515 7773779 10319320 9569023 9797459
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 KSR1 â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
GRB2 KSR1 â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
NRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 KSR1 â—¼   ENZYMATIC_REACTION ✅ 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
PTK2B GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9560226 10329689 8695788 16713569 19380485 9091579 10749687 10354709
IRS2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7559579 11788580 10358772 11305324 9852124
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
GRB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 145.0 1.0 Omnipath 9544989 9872323 7642581 15746962 11726515 8621483 23334917 16520382 11997436 21706016 10359574 8950973 7664271 16713569 16893902 16906159 21988832 19323566 9009162 10716926 11964172 7629168 9815779 10592173 9716598 8647802 28166272 7773778 7773779 18778683 8188688 10319320 8810325 9344843 23452850 11960376 8816480 10025673 7510700 8940013 12955078 9697839 12345678 10477741 8493579 8943292 12577067 7862167 9199344 8112292 7898932 10207103 8695800 19531499 10570290 7760801 20005866 19380743 9447984 8235613 8479540 7527391 14679214 8479541 17474147 7514169 7629138
HRAS YWHAB â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
HRAS KSR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
HRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS YWHAB â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
HRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
SOS1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12628188 10208427 16713569 10913276 23331499 18454158 15507210 10592173 17673906 17496910 26721396 20133692 19141281 23132018 11560935 9447984 9690470 17084389
NF1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8628317 19777070 26635368 24431436 19718661
HRAS PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 9069260 9113989 8052307 24412244 17540175 9931431 11313862 14724584 10592173 9150145 8665852 10783161
IFIH1 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16177806 17020950 15210742 15210743 16306936 16127453 12702806 16858409
IRS2 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9113989 22810696 9374521
KRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
KRAS MAP2K1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
KRAS YWHAB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12068308 23352452 25907612 15035987
KRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
KRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
KRAS KSR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
KRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
MAPK3 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK1 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
NRAS KSR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MAP3K7 KSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11741534 12941695
PPP2CA KSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
KSR1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8503013 19541618 15090600 11741534 1330321 17613518 11940661 18332145 7992057 8248196 15520859
KSR1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 9858547 8248196
KSR1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 8248196
KSR1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 17145710 19541618 27086506 17613518 11909642
LATS2 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21118956 25086053
NRAS MAP2K1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
PPP2CA MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18039929 16680151 1716348 10995457 18042541 18588945 20626350
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
MAPK1 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
MAPK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
PPP2CA MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945 20626350
MAP2K2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 19901323 17081983 11704645 9694850 12750173 1411546 19690332 12932319 18799465 16497976 18083107 11134045 8626767 9006895 17389395 19219045 15342917 9447970 16887817 23331499 17569879 7867743 7559390 21071413 19534553 8226933 20068231 8223433 17272394 93330262 15851026 15811950 26987942 18988627 19494114 18669648 19541618 11242034 15466476 18691976 1381507 17906627 11986622 19933846 8376945 11971971 17192257 11136732 11948414 7898932 7687743 9731057 19651622 11730323 16464493 18983981 11251083 11118451 15580310 19369195 18707149 12920017 15951569 15466214 10746662 15212693
MAP2K2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 21675959 11704645 9694850 17081983 7565670 12750173 19690332 12932319 11823456 18799465 15592455 11337027 18083107 21365009 12788955 11134045 19219045 17389395 9447970 15342917 23331499 19534553 17569879 7559390 23047924 8226933 8223433 17272394 15851026 15811950 19494114 18988627 18669648 11549292 23519423 19541618 18691976 1381507 16293107 17906627 11986622 19933846 8376945 19053285 16094384 11971971 17192257 11136732 11948414 8388392 7898932 9731057 11730323 18039929 11118451 19369195 12920017 15951569 15466214 10746662
MAP3K2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8226933 15315965 17052767 11971971
MAP3K7 TAB3 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
MAP3K7 TAB3 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
PPP2CA MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18299321 17079228
TAB3 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 21903422 14633987 14743216 17158449 17384642 14670075 22081109
NRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
PRKCZ MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
PPP2CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 10592173 7780739 18588945 2154696 20626350
SHC1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10996427 23584453
MAPK1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12351702 18669648 9199329
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8939914 12832467 9915826 17906627 32296183 19282669
MAPK1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10197981 8816480 9922370 8626428
MAPK1 NRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10938135 17088940 16093479 16613989 11467847 7791761
NRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
PRKCZ MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
PPP2CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 18588945
MAPK3 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12351702 17440046 9199329 20047289
MAPK3 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 23602568 8939914 12832467 17906627
MAPK3 NRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10938135 17088940 16093479 16613989 11467847 7791761
MAPK3 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29145629 7478566 23331499 8816480 7739560 17570479 9922370
MST1R YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 12919677
MST1R YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 12919677 14505491
NRIP1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10659697 12773562 11266503 9920921 16189514 10364267
NRAS YWHAB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12068308 23352452 25907612 15035987
NRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
NRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
SOS1 NRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 7923364 11560935 9690470 21779497 8493579
NRAS PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8052307 7820549 9150145 8665852 21779497
NUAK1 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17739896 24171924 22516431 18088087 19367720 19690332 20354225 19413330 18669648 29106388
TBK1 OPTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 27247382 29246869 29594070 27035970 21617041 18307994 22364875 29755463 21903422 26376340 29867991 23794264 26101267 26365381 21862579 27538435 25026213 25923723 29282133 29626651 29971063 30294276 30223576 20174559 26266977 23414517 27086836 23178947 22518139 27906974 25803835
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PRKCZ YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16189514 10620507 21900206
PTK2B SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 7544443 10749687
SFN YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
SHC1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 9544989 8631299 8621483 8950973 10891441 10783152 9278309 17673906 9344843 8294403 8021500 10025673 7520523 12955078 12577067 9199344 19531499 7760801 10570290 19380743 8235613 10675333 8114695
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAB YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17085597 12657644 12426317 15071501
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAG YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178
YWHAE YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAG YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17085597 21827211 12426317 15324660 15071501 12657644
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501