Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
APBB1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ARAF YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
ARAF MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18039929
MAP2K1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15994315 15121878
MAPK1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
NFATC4 YWHAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10611249 8005424
YWHAZ PFKP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SP1 SGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9415398 10614661
YWHAG YAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAQ YAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12535517 5216053
GSK3B GLIS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16537363
CUL3 GLIS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16740475
EMC8 EMC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
WNK1 OXSR1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16832045 0604607103
MYH9 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP3K2 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SRPK1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213315 11118213
SP1 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17889508 16452190
SP1 CLDN4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23868418 16714763
PPP1CA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8288823 20186153
ATXN1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA AKT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288823 20186153
YWHAZ PAK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
UBE2I ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ANKS1A YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CENPJ YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16516142 8007368
MAP3K2 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SRPK1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAE MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ATXN1 YWHAE â—¼   COLOCALIZATION 2.0 0.8 intact 5216393 12757707
MAP3K2 YWHAE â—¼   COLOCALIZATION 2.0 0.8 intact 9452471 5221876
YWHAZ EIF3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAQ HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA8 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PPP1CA MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ZYX ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
YWHAZ ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216393 12757707
WNK2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
WNK1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5216393 12757707
YWHAH MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAQ MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
WNK1 MAP3K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14681216
HMGN2 WNK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
WNK1 MAP3K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14681216
WNK1 ZYX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20936779
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
OXSR1 WNK1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
NEDD4 AKT1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19953087 23195959 31390487
KLHL3 CUL3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8427680 23665031
YWHAB MAP3K2 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
ARAF HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 29777862
YAP1 GSK3B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24976009 29789528
1433F WWTR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
YWHAG MAP3K2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5217174 15324660
1433B SRPK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 15324660
CLCB WNK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26496610
RPGF5 WNK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AASD1 WNK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STALP WNK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433F WNK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
WNK1 KAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 20936779
WNK1 CLH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20936779 26496610
WNK1 ZYX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20936779
1433B CGNL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433F CGNL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433F WNK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RPGF5 PLEC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RPGF5 KAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT1 BAD â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 9346240
AKT1 GSK3B â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 15829723
AKT1 GSK3B â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 23552696
WNK1 WNK2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
FHL3 WNK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 33961781
FHL3 ZYX â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AKT1 HSP7C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24462114 31980649 16027165
SRPK1 1433G â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17353931 15324660
AAMP WNK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
T22D4 WNK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
1433B WNK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24255178
METL6 WNK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
KLHL2 KLHL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 32296183 33961781
T22D4 STK39 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
T22D4 WNK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
T22D4 WNK3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ARAF YWHAZ â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
OXSR1 WNK4 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
YWHAB YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 8008024 17974916 1602907
YWHAZ YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5217040 15161933
ATXN1 YWHAZ â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 12757707 5216393
YWHAZ ATXN1 â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 12757707 5216393
STALP CLH1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 33961781 16716190 26496610
CLH1 HSP7C â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27684187 29568061
1433B ARAF â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31980649 29777862 24255178 25852190 32707033
YAP1 YWHAG â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5217174 15324660
CLCB AAK1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
WNK1 PLEC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 27173435 30021884
KLHL2 WNK4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23838290 24641320
YAP1 YWHAB â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
YAP1 YWHAQ â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
YAP1 1433B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17974916 27684187 20048001 25796446 31501420 19439659 30472188 33961781 24255178 24366813
CUL3 KLHL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 23838290 33961781 21145461
1433G WWTR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 20936779
YWHAG PAK4 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 29100370
PAK4 YWHAG â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5217174 15324660
CENPJ 1433F â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26496610 26638075
1433G CGNL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 20936779
BAD YWHAQ â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
YWHAZ ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8009399 19933840
BAD 1433G â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31980649 10880354 33961781 20936779
BAD 1433B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21900206 28514442 16189514 31980649 11697890 33961781 24255178 9369453
OXSR1 WNK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17721439 16832045
1433B PAK4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 17353931 33961781 29100370 24255178 32707033
1433F PAK4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32707033 17979178 33961781
YWHAE YWHAG â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CENPJ 1433G â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16516142 20936779 26638075
1433G WNK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 15324660 20936779
HSP7C WNK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 29568061
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
NEDD4L SGK1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AKT1 BAD â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
1433F ARAF â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 11969417 29777862 17979178 26496610 33961781 25852190 32707033
YWHAZ BAD â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 1204662 8005727 11526496
BAD 1433F â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 11697890 21988832 17979178 33961781 9369453
SGK1 NEDD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19953087 11696533 12729930 20730100
YAP1 1433F â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27684187 25751139 25796446 26933062 30472188 33961781 24255178 24366813
KLHL3 CUL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 23576762 23387299 25416956 23838290 26100637 23665031 23573258 25502805 25250572 30819806 33961781 26286618 23453970
ATXN1 YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 12757707 5216393
YWHAE ATXN1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 12757707 5216393
YWHAE ATXN1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 12757707 5216393
KLHL3 WNK4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25313067 23576762 23838290 23665031 23962426 26435498 26349538 26286618 23453970 24641320
1433G 1433F â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17979178 26496610 22863883 33961781 15324660 26344197
CLH1 CLCB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15533940 21411634 26496610 34079125 12426379
KLHL3 WNK4 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
COPS5 VHL â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
YWHAG ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
1433G ARAF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31980649 28628118 29777862 17353931 28205554 25852190 32707033 15324660
YWHAB BAD â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PAK4 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23642861 11950587 11278822
MAPK1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8929531 10597268 12566304
MAPK1 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAP3K3 MAPK1 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
SGK1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19447520
YAP1 1433G â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 28628118 27684187 17353931 25796446 33961781 24255178 28205554 24366813 15324660
SUFU GLIS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15367681 16316410
EMC2 EMC8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16189514 25416956 32439656 22119785 31536960 26496610 27342126 33961781 26186194 30021884
YWHAZ LCP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 17353368 8007777 20062066
AURKB HDAC9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22865920
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
AKT1 GSK3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19713527 8524413 23824745 16009706 29464284 20856200 19995607 16123141 20682768 27563096 14645548 15688030 22337773 11035810 17428466 18505846 15470047 14701753 16282323
PAK4 YWHAZ â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
PAK4 1433G â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17353931 33961781 29100370 32707033 15324660
VHL UBE2I â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20844582 24002598 20300531
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
MAP3K2 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11343802 23331499
PPP2R5D MAP3K3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
WNK3 SLC12A6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24043619 21613606
BAD YWHAZ â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
MAPK1 RPS6KA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
YAP1 YWHAZ â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ARAF MAP2K1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
AKT1 GSK3B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
AKT1 BAD â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15998799 10358075 25241761 11500364 9381178 11994280 23085457 15722337 19667065 15784622
1433F 1433B â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 17979178 26496610 33961781 24255178 26344197
1433G 1433B â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 17085597 33961781 24981860 24255178 15324660 26344197
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GSK3B YWHAZ â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CUL3 KLHL3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EMC2 EMC8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MAPK1 APBB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14697653
YWHAE ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19608861 20936779 25852190 17979178
YWHAZ ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19933840 20936779 25852190 20052757
YWHAG ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17353931 15324660
ARAF MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18039929 8131746 8394352 24114843 15175348 15466476 94178255 7936666 7731720 7873542 7624324 8157000 8039496 8621729
AKT1 BAD â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10722653 10949026 11715018 11756412 11923280 15169778 15808505 16697215 17052453 17680028 18372248 18570873 18636226 20138985 20214616 20398329 20832730 9812896
PPP1CA BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 10811615 17274640 22820751
YWHAH BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21988832 11697890 8929531 9369453 17979178
YWHAQ BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 21988832 15694340 11697890 8929531 16713569 9369453 15280438
AKT1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 137.0 1.0 Omnipath 10880354 19052636 21506126 20028971 21303971 20214616 11994280 8929531 17570479 12832477 17555943 25241761 11715018 18636226 21998731 9812896 17680028 11500364 18385666 18707149 10201527 18218901 11983683 10490655 19030972 19667065 11756412 11020382 16931767 18372248 15808505 20138985 18046313 18669648 19121340 19703413 11714830 10949026 15972258 16341064 10358075 23085457 18220336 10516287 12897128 9580112 9651683 11923280 9346240 16697215 19690332 11493700 15452053 12040186 10826997 12175651 15722337 14737178 11882383 15226424 10521512 15023346 15784622 17052453 16044149 16403219 12444011 20166139 20398329 9381178 11544290 15037618 12767520 15280015 10230394 10558990 15998799 10082559 11577096 10837486 15169778 10611223 23109003 12954615 22094462 11438654 11312610 11254732 21540285 10383455 19664994 10722653 20832730 18570873 10926925 17270021
RPS6KA2 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 55.0 1.0 Omnipath 11983683 10880354 20166139 9346240 11493700 9381178 15037618 15280015 10230394 10558990 8929531 19641507 18669648 10837486 10611223 15226424 12954615 10521512 10949026 15972258 18707149 12897128 19282669 16403219 17270021
SP1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12220517 16797880 20506264 20121399 20882567 18372343 10727414 21170990 17889508
MAP3K2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8226933 15315965 17052767 11971971
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
MAPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8939914 12832467 9915826 17906627 32296183 19282669
MAPK1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16039586 28646232 18451303
MAPK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19318349 20882567 16377629 18775330 8226933 14744793 16079281 11904305 9604935 15212693 14593115 8388392
MAPK1 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15657420
RPS6KA2 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15187187 21233202 16286006 15657420 15239952
PRKCD YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9705322 12861023
PRKCD KCNJ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8621594
PRKCD YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9705322 16024783 12619878
SGK1 WNK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27517916 23054253 28493961 17360471 23673010 19706464 29352074 21248166 26491696 25805816 24535442
SGK1 NEDD4L â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 47.0 1.0 Omnipath 20621254 20166139 18767875 23589291 20230923 12911626 11742982 19413330 19664995 15586017 20068231 17570479 16189514 27517916 15140763 18669648 12729930 20730100 18691976 19651622 15328345 22301619 15677482
SGK1 KCNJ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8621594 12878206 12684516 17570479 29352074
SGK1 MAP3K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 12761204 18220336 19369195 18691976 12761205 19690332 12392720
YAP1 WWTR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
YAP1 WWTR1 â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
AKT1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 27979972 25360797 26804165 28273460 25751140 24101154 25751139 34052254 25362852 28114269 28793266 26265440 31239271 25601544 28474680 33630828 26119935 27144834 27425596 25531778 34206989 34465890 21945154 25195862 31792377 18640976 28775168 32015438 32523092 22234184 33536280 33622361 30600590 24362629 34155345 24658687 21060948 33162394 20153295 26668327 21730131 26549256 21666719 25605730 26039999 34226698 20823509 34516278 27033705 32064037 32271880 32513743 33990468 24812269 32053631 32929029 34058200 25772246 26364602 27765911 26678338 27979971 33552953 28171658 34129887 21376238 28416665 25998128 25109332 12535517 31988076 26933062 26598551 25373897
WNK1 OXSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 25389294 17190791 29581290 35044719 18270262 24555568 27050278 16083423 16832045 23026752 17721439 24191005
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
MST1R YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 12919677
AKT1 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
YWHAB YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17085597 12657644 12426317 15071501
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
GSK3B SUFU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17444818 27234298 16611981 20537194 10671551 20080742 19797085 16039586 19575820 21317289 12040186 17052453 12615961 18455992 16371461 11274345
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
PPP2R5D AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18039929 19216069 10026142 10995457 18042541 20452955 18559511 18588945 16680151 16406523
PPP1CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
AKT1 WNK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21355052 16081417 14611643 22119528
AKT1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 99.0 1.0 Omnipath 17428466 15207235 17145710 12052830 10729337 8250835 11756412 11923280 16914735 17623045 16697215 8524413 12054501 20398329 18372248 21506126 20028971 12040186 15808505 16543730 20138985 23331499 21303971 16009706 10385618 20214616 23180781 9373175 16039586 15829723 18988627 16282323 11577096 11035810 18669648 18216173 15169778 12851486 16123141 11882383 23109003 9065430 18691976 22094462 10949026 22710759 11715018 12459251 18636226 17192257 11254732 11278246 20858269 9812896 9582355 15023346 17680028 19369195 7945242 12900420 23552696 18387957 10722653 20832730 18570873 12147701 18505846 17052453 17693255 18218901
AKT1 ZYX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17572661
AKT1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11756412 9705322 11923280 16697215 20398329 18372248 12865427 15071501 15808505 20138985 20214616 15883165 15169778 10949026 12861023 11715018 18636226 9812896 17680028 11956222 10722653 20832730 18570873 16376338 17052453
AKT1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 ATXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15757972 15824120 17540008 34302818 24903464 29212253 33709453 12741986 17570479 21722762 29758256 23719381 20037628 23213356 12757707 24858692 20477910
AKT1 MST1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 12919677 14505491
AKT1 YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
YWHAE YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAG YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAG YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17085597 21827211 12426317 15324660 15071501 12657644
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
MAP2K1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17081983 21105670 16964243 14617795 30711629 18547980 8382613 17188038 17192257 15020233
PPP2R5D GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
WNK3 WNK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18270262 22032326 34083438 25542968
WNK2 WNK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20936779 22032326
WNK1 STK39 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 18270262 18088087 16083423 16263722 17190791
WNK1 SLC12A6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 24393035 27485015 24043619 27782176 19665974
WNK1 SYT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15350218
WNK4 STK39 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15930150 27942049 24097229 16990453 16083423 20463172 19633012
MST1R YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 12919677 14505491
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501