Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SP1 AKAP12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17626016 20568114
SP1 CLDN4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23868418 16714763
SP1 CXADR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22190856
EGFR RAB7A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18776048 0806158105
ESR1 EPHB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17685427 20484412
SP1 EPHB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9918860 10751319
TWIST1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22056872 22457607
SP1 SLC3A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17023546
SP1 SLC7A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17023546
EGFR JUP â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
LSR AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EGFR AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24189400 24797263
EGFR EPHA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15657067 24797263
DSG2 JUP â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
DSG2 DSC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11853539 21220045
SLC3A2 SLC7A5 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CTNND1 EGFR â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
OCLN TJP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
ESR1 CLDN4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
YES1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 22430206 11160627
ESR1 NOTCH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
SLC3A2 SLC7A5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
SP1 ITGB5 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10964912 11007770 11013220 15001984 17705132 18353785 21252118 23338822
EPHA2 CLDN4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16236711
EGFR CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 17145710 22558232 18950621 23481205 25402006 12040186 24797263 9535896 17389395 20068231 19568798 27316454 14585353 17496910 24189400 15657067 24658140 31980649 26067913 15951569 14996911 17016520
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
WNK1 SYT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15350218