Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EPN1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19054389
AP1B1 DNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10398591 11050117
AP1B1 CLTA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8909539 11050117
PACS1 AP1G1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16977309 5219086
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2A1 CD74 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2A2 CD74 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 CD74 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15749704 15911768
AP2S1 CD74 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15749704 15911768
CHEK2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
HLA-DRA CD74 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218024 16242130
CD74 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218024 16242130
FOXA1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24440874
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNX9 DNM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217519 15703209
SNX9 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217519 15703209
DNM2 SNX9 â—¼   COLOCALIZATION 2.0 0.8 intact 5217519 15703209
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
NUMB EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221644 9303539
HLA-DQA2 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
SH3GL2 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HLA-DRA HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
PACS1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
LRRK2 TBC1D22B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
PACS1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AP2S1 NECAP2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
ATM CHEK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 10973490
EPS15 NECP2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 19380743
SNX9 DNM2 â—¼   COLOCALIZATION ✅ 0.81 0.81 mint 5217519 15703209
AP1B1 AP2A2 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
AP2A1 AP2S1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RUN3A AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A EPS15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A NECP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A AP2S1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2M1 CLH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19380743 26496610
CLH1 EPS15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18524853 26496610
VAMP4 EPN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EPN4 AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP2S1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP2M1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PP6R2 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PP6R2 AP1S2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PP6R2 AP1G1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2M1 PP6R2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
GP156 AP2M1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GP156 ARRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GP156 AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GP156 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GP156 AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GPBL1 AP2M1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GPBL1 AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GPBL1 AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GPBL1 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GPBL1 AP2S1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AMPH AP2S1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AMPH AP2M1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2A2 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
LSR AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SNX9 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CFTR AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
AP2A1 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
NUMB AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 23211419
PNKD AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
EGFR AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24189400 24797263
AP1G2 AP1S1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 9733768 16713569
ARRB2 AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32962859 17620599
SNX9 AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SNX9 AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LSR AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SNX9 AP2M1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NUMB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16273093 25754235
LSR EPS15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DNM2 SH3GL2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
AP1G1 AP2M1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
ARFG1 ARF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26344197 19020038 9733781 16332543 16189514
AP2M1 KI13A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AP1S2 EPN4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
AP2M1 EPN4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19380743
NECP2 AP1G1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14665628 26186194 33961781
NECP2 AP1B1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NECP2 AP2S1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NECP2 AP2A2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NECP2 AP2A1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
K1984 AP1B1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AP2A1 AMPH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 12057195
AP1S2 AP1AR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
EPS15 AP1B1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 12538641 19380743
AP2M1 AP1G2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EGFR AP2S1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24189400 25754235 24797263
AP1B1 AP1G2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
AP1G1 CLTC â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AP1B1 AP2S1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ATR CHEK2 â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10973490
SNX9 CLH1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11799118 12952949
ESR1 FOXA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23403292 25303530 28336670 27926873
AP1M2 AP1S1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
AP1B1 CLH1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11451993 9280305
PRKDC PP6R2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 20065038
AP1B1 CRYBB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
AP1B1 MSGN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
AP1B1 ARRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11877451 10097102 12070169
EGFR AP2A2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31959764 24797263 23956138 8548289 24189400
CFTR PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
EP300 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33742100 30110629 20808282
AP1B1 TBC1D22B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
AP1M2 AP1S2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
AP2A1 NUMB â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
AP1G1 ARF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11926829 16189514
AP2A2 EPN1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
EP300 CLH1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 21988832
CLH1 ARRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9169477 10097102 32962859
ATM PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10464290 10608806
CUL3 PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26949739 21145461
AP1B1 GPANK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
AGR3 AP1B1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
AP1B1 PSORS1C2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
AP2A1 AP2M1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CD74 HLA-DRA â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
GPANK1 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
AP2M1 RUN3A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 16189514 16713569
EPN4 SMAP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 29395067
AP2M1 NECP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26186194 28514442 24189400 19380743
AMPH AP2A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EPS15 AP2M1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26186194 28514442 24189400 19380743
EPS15 AP2S1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 19380743
EGFR ARRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
EGFR NTRK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
EGFR SNX9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
AP1B1 AP2A1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AP1B1 FARS2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PARK2 SNCA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AP1G2 AP1S2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EGFR SH3GL2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR AP2A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31959764 24797263 23956138 25754235 20029029 24189400 7534311
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
EGFR EPS15 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
AP1B1 FNDC11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
AP1B1 MYG1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
AP1B1 LDLRAP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
AP2M1 AP2S1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
DNM1 SNX9 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AP1M2 AP1S3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
AP2M1 AP1S3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
AP2M1 EPN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
EPN4 CLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12429846 12538641 26496610
KI13A AP1B1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32296183 11106728
EPN4 AP2A1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 12429846 16189514 33961781
EPN4 AP1G1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12429846 12538641 16189514 15758025
AP1B1 AMPH â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 9280305
AP1M2 AP1G2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
AP2M1 AP1S1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
AP2M1 AP1S2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
EPS15 AP2A1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8662627 9049247 10764745 19380743 10953014
EGFR AP2M1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31959764 24797263 31980649 24067654 23956138 25754235 20029029 24189400
AP2M1 NUMB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 28514442 24189400 23211419
ATM CHEK2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
FARS2 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
AMPH DNM1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
DNM2 SNX9 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FNDC11 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CLH1 AP2A2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17052248 26496610 9280305
ARFG1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22423108 29513927 22363216
AP1B1 ATM â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9707615 10608806
VAMP4 AP1M1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11598115 14608369 16189514
NUMB AP2A1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17203073 23211419 12942088
AP2A1 EPS15 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
AP2A2 ARRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
ARRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
ARRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
HLA-DQA2 CD74 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
ESR1 CLDN4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
DNM2 DNM1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FOXA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21572391 20501593 24290378
HLA-DQA1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
AP1B1 AP1M2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
AP2A2 EPS15 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
AP1G1 CLH1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 11387476 11451993 17052248 21411634
EPN1 EPS15 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
DNM1 SH3GL2 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
EPN1 CLH1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 26496610 10692452
AP2M1 TGOLN2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AP1M1 AP1S1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
AP1M1 AP1S2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
AP1B1 AP1M1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
AMPH CLH1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10748223 9603201 9280305 9195986
AP1B1 AP1S2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
AP1B1 AP1S1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
EPN4 AP1B1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 28514442 12429846 12538641 33961781
AP1G1 AP1B1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 11409905 9733768 23415225 26344197 22939629 7593184 10535737 10747088
AP1M2 AP1G1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 10535737 26186194 28514442 16189514
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
AP1B1 AP1G1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
EPS15 EPN1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10791968 18375383 18200045 15809337 9723620 21115825 16429130
EPN1 AP2A2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12057195 9723620
AP1M2 AP1B1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 26344197 10535737 26186194 28514442
AP1B1 AP2M1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
AP1G1 AP1M2 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP1G1 AP1S1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
AP1G1 AP1M1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
AP1G1 AP1S2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ATR CHEK2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
AP2A2 AMPH â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 8552632 28514442 10748223 9280305 9195986
EPS15 AP2A2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 10809762 18362181 8662627 9049247 26822536 19380743
AP2A2 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2A2 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DNM2 AP1S3 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
CLTC AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
EPS15 EPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 16429130 18375383 35044719 9723620 10393179 18200045 15809337 21115825 10791968
CLTA AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1B1 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
AP1G1 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 DNM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 CD74 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 HLA-DRA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 DNM2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
CD74 AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1M1 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
CLTA AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1M2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
DNM2 AP1S1 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
HLA-DQA1 AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1S1 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1S2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1S2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
AP2A1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A1 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A1 HLA-DRA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A1 CD74 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A2 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A2 CD74 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A2 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A2 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A2 HLA-DRA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DPA1 AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DRA AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CD74 AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA2 AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA1 AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
HLA-DPA1 AP2S1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA2 AP2S1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA1 AP2S1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CD74 AP2S1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DRA AP2S1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
ATM CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 176.0 1.0 Omnipath 26683224 17303408 28852018 10713094 20080130 27545311 9488723 15342622 23941746 26485758 28937603 15279786 24882580 10744722 15125777 25746763 18583988 28051860 17570479 16531125 21329876 23892398 19607708 16940182 26643553 20396397 28259974 25361978 17660363 15459660 19375317 25247188 16311512 23118481 20498628 22030216 25613496 22420423 9407949 17918214 12493754 20859824 26158765 15700044 27558808 11901158 27602502 20637859 16163361 20599567 23638118 16481012 12242661 23847781 12024051 15140942 11728459 12454775 16936775 25450480 28950914 26295265 20160490 22319212 24349411 18006705 20723763 18678890 12805407 20860841 23386996 24050180 11668173 27271602 29304495 12447382 24798733 9889122 23347679 18794134 21147465 21421565 26516160 17715138 21376743 19440053 12773400 10973490 17174984 26442630 15694385 11877377 29022904 18809224 11850621 18787700 12718885 19481982 22743550 20372057 15212693 16085488 19101576 29555944 25954303 24473398 18087292 16794575 24492479 24244353 19793801 25404613 21102523 29156743 23253087 16997395 7575488 25808488 20647331 18584027 21851590 21315088 23705030 15629715 29741650 21772273 11025670 18590585 26610585 15964794 29434792 20068082 23006513 19881958 19230643 12607003 24769180 25249630 15024084 19772495 25714019 18603484 25173936 23666059 19473886 27568553 22808196
ATR CHEK2 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 21722802 20859824 26683224 18677104 19622404 15798197 19793801 27545311 23137030 19836377 20647331 20599567 19282663 19658174 17116885 16481012 17582221 11715017 17384638 29741650 12024051 18802408 10973490 9857181 26442630 15459660 17296725 11877377 17102137 12493754
ATR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12186630 22592045 22057367 24500207 18077418 16908529 15507430 29309644
CD74 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 SH3GL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CD74 DNM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 DNM2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
PRKDC CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 77.0 1.0 Omnipath 31959038 12607004 22669845 18948271 16794575 24492479 15829965 23684611 12805407 20406977 26929199 21482692 27818175 20660628 33870196 11668173 21731742 33879618 15618221 11901158 24421316 21099343 12386164 15096610 24415760 12447382 12855706 15213307 16150728 20599567 16024600 17570479 12447371 28750002 34244606 33901880 15367709 26505995 16940182 33747205 11025670 12024051 24844881 15668230 10973490 20713355 33961649 19151762 16936775 16798742 12607003 30001349 18644861 25361978 20305300 11390408 20501833 15361851 16982735 23380594 15674326 17237275 20160490 20498628 33851958 15282313 25550082 31609975 15975956 11085506 12493754
HLA-DQA1 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA DNM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA DNM2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
HLA-DRA CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 CLTC â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
SNX9 DNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18353773 16137687 15703209
HLA-DRA DNM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 DNM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 DNM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 DNM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 DNM2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
HLA-DRA DNM2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
HLA-DQA2 DNM2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
HLA-DPA1 DNM2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
SNX9 DNM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 27107012 15703209 15299020 18388313
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
SNX9 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 16316319 24658140 25402006
EGFR EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 17389395 10953014 24269888 19534553 25260758 19583965 19690332 15951569 9049247 17016520
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EGFR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23956138 23178489 18237807 18789131
EPS15 SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HLA-DPA1 SH3GL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA1 SH3GL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA2 SH3GL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DRA SH3GL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
LRRK2 SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 25501810 24778241 22998870
LRRK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20127702 22924508 22658533 24907399 19576176
PRKDC ATM â—¼   KO_DOWN_REGULATES ✅ - -1.5 1.49 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368