GRB2
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
DVL2
|
DACT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11970895
16446366
|
DVL2
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
DVL2
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17199046
12958364
|
DVL2
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17199046
12958364
|
DVL2
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17199046
12958364
|
DVL2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
DVL2
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17199046
12958364
|
DVL2
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17199046
12958364
|
GRB2
|
SHANK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SHANK3
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
DLGAP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SHANK3
|
CLTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
SH3GL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
KIF4A
|
KIF4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10747093
10804209
|
FXR1
|
ACTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SH3GL2
|
ACTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
EFNB2
|
ACTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10219243
11747816
|
GRB2
|
ACTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
WASL
|
ACTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10219243
11747816
|
ACTG1
|
EFNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10219243
11747816
|
ACTG1
|
EFNB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10219243
11747816
|
ACTG1
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10219243
11747816
|
SH3GL2
|
ADAM9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10531379
5211924
|
AP1B1
|
DNM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10398591
11050117
|
AP1B1
|
CLTA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8909539
11050117
|
AP2S1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
GRB2
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
AP2A2
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A1
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
AP2A2
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A1
|
CD74
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A2
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
AP2M1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A2
|
CD74
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
MAPK1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
GRB2
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
AP2M1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2B1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2B1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
CD74
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
MAPK1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
GRB2
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
AP2S1
|
AP2M1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
CD74
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
MAPK1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
GRB2
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
AP2S1
|
CD74
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
HGS
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
MAPK1
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
ARRB1
|
CHRM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
CBL
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17255943
5219572
|
SH3KBP1
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
5219572
17255943
|
ASAP1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SH3KBP1
|
ASAP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17255943
5219572
|
ASAP1
|
SH3KBP1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.8
|
0.8
|
mint
|
5219572
17255943
|
ITCH
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12226085
5215735
|
FYN
|
CBL
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.8
|
0.8
|
mint
|
5217342
15556646
|
CBL
|
FYN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.8
|
0.8
|
mint
|
5217342
15556646
|
CBL
|
MET
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5215187
11894096
|
CBL
|
SH3GL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11894095
16713569
|
HLA-DRA
|
CD74
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218024
16242130
|
CD74
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218024
16242130
|
CLTA
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
MAPK1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
FYN
|
DAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
DAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DLGAP4
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DLGAP4
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SH3GL1
|
DNM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10542231
5211933
|
FXR1
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
GRB2
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15834155
5217666
|
ITSN1
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15834155
5217666
|
DNM2
|
SH3GL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10542231
5211933
|
DNM3
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SH3GL3
|
DPPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
DPPA4
|
EMD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SH3GL3
|
DPYSL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
EGF
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20178463
17081983
|
EGF
|
EPS15
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24269888
25728925
|
SH3GL3
|
EGFL6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HGS
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20308550
0911188107
|
SH3KBP1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11894095
|
SH3GL2
|
EMD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SH3GL3
|
EMD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
GRB2
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ITSN1
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5211195
10064583
|
EPS15
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SH3GL2
|
ERH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
FXR1
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
FXR1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
LCP2
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6546918
15929943
|
WASL
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11340081
16525419
|
FYN
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9694876
7737275
|
GRB2
|
GSTM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
MAPK1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8994038
|
HGF
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16397249
17667909
|
STAM2
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
MET
|
HGS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
8380735
|
HLA-DQA2
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
SH3GL2
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HLA-DRA
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
SH3GL2
|
IL6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
ITCH
|
SH3GL2
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5216835
14684745
|
SH3GL2
|
ITCH
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5216835
14684745
|
ITSN1
|
WASL
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5214632
11584276
|
MAPK1
|
L1CAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
MAPK1
|
L1CAM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17151951
21080252
|
LRRK2
|
TCEA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
LRRK2
|
SH3GL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22998870
|
MAPK1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
SH3GL2
|
TCEA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SH3GL3
|
TERF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
ERH
|
WTAP
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
DNM2
|
DNM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
GRB2
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
KIT
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
25737303
16780420
15315962
8950973
|
GRB2
|
RET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
AP1B1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.81
|
STRING
|
36370105
|
AP2A1
|
AP2S1
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
AMPH
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
AMPH
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
AP2S1
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
AP2A2
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26344197
|
AP2A1
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26344197
|
EGFR
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24189400
24797263
|
DAB2
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22323290
34079125
|
AP2B1
|
SYNJ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
34079125
|
AP2S1
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
ARRB1
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
18544533
17947233
|
ARRB1
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23208550
20505072
|
FYN
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17474147
16636290
|
ASAP1
|
CD2AP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31413325
15632162
|
NTRK1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21570973
25921289
|
ROCK2
|
ROCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
DNM2
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
AP2A1
|
AP2B1
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
AP1G1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.82
|
STRING
|
36370105
|
AP2A1
|
AMPH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
12057195
|
EPS15
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
12538641
19380743
|
AP2A2
|
DAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22323290
11247302
|
EGFR
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24189400
25754235
24797263
|
CBL
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12226085
19341794
|
GRB2
|
DNM1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
5217666
15834155
|
EFNB2
|
EFNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
EPS15
|
STAM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12551915
16713569
|
STAM2
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25416956
32296183
17235283
|
AP1G1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
AP1B1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
AP2B1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
CBL
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
AZU1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.83
|
STRING
|
36370105
|
ITSN1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28484035
32203420
|
EGFR
|
EMD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24797263
28065597
20937808
|
DNM1
|
DNM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
EGFR
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
31959764
24797263
23956138
8548289
24189400
|
EGFR
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
24189400
24797263
23956138
7534311
|
SYNJ1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
28514442
12057195
26186194
|
CD2AP
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
17474147
31413325
10339567
16713569
|
KHDRBS1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
8374603
22641034
|
AP2B1
|
AP2M1
|
â—¼ CORRELATES
|
|
+
|
0.85
|
0.85
|
CCLE
|
31978347
|
LRRK2
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31046837
19625296
|
FXR1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
29395067
21653829
|
MET
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
6538879
18273061
|
MET
|
CBL
|
â—¼ UBIQUITINATION
|
✅
|
|
0.86
|
0.86
|
mint
|
11894096
5215187
|
SH3GL1
|
DPPA4
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
21900206
2001699
8089645
|
EPS15L1
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
PDCD6IP
|
SH3GL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
AP2A1
|
AP2M1
|
â—¼ CORRELATES
|
|
+
|
0.86
|
0.86
|
CCLE
|
31978347
|
AP2B1
|
AP2S1
|
â—¼ CORRELATES
|
|
+
|
0.86
|
0.86
|
CCLE
|
31978347
|
CD74
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.86
|
STRING
|
36370105
|
AMPH
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ITSN1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
34079125
18654987
22558309
|
EPS15
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
19380743
34079125
|
EPS15
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
26186194
28514442
24189400
19380743
|
EPS15
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28514442
19380743
|
CLTC
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
WASL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31980649
25402006
24658140
|
EGFR
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
STAM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10993906
11687594
15212941
17403676
|
PDCD6IP
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
AP1B1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ARHGAP8
|
SH3GL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
SH3GL1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
SH3GL2
|
SH3GL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CALM1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
SH3GL1
|
SH3GL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
AP2B1
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ARHGAP8
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ARHGAP8
|
SH3GL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CD2AP
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
DVL2
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11742073
16189514
16713569
|
EGFR
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31959764
24797263
23956138
25754235
20029029
24189400
7534311
|
LCP2
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9716598
10204582
19635790
10477741
|
EPS15
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
17474147
7797522
19109251
|
CBL
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
GRB2
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
AP2M1
|
AP2S1
|
â—¼ CORRELATES
|
|
+
|
0.88
|
0.88
|
CCLE
|
31978347
|
CBL
|
CD2AP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
FYN
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
EPS15
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
SH3GL2
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
AP2A1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
GRB2
|
KIT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
GRB2
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
AP2M1
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
16713569
31340145
|
AP1B1
|
AMPH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
28514442
9280305
|
EPS15
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8662627
9049247
10764745
19380743
10953014
|
EGFR
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31959764
24797263
31980649
24067654
23956138
25754235
20029029
24189400
|
EGFR
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
25402006
24658140
|
EGFR
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
25402006
24658140
|
RET
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
7665556
10995764
15677445
9393871
8183561
32062451
16189514
|
NTRK1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10748052
11733534
25921289
|
AMPH
|
DNM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
ASAP1
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
DNM2
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
SH3GL2
|
SYNJ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
20332299
|
EGFR
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
16829981
|
IGHM
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SH3GL2
|
ZNF580
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
L1CAM
|
ACTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16904324
11222639
17223356
|
MAPK1
|
AMPH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15262992
|
AP2A1
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
AP2S1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12577067
|
STAM
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
0509166103
7102318
16636290
|
GRB2
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
21706016
31980649
20936779
21988832
28514442
19380743
17474147
|
ASAP1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
0509166103
7102318
16636290
|
EGFR
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23158001
24797263
25872741
31182136
10635327
26055326
14505571
15210722
32714745
23774213
19155296
11370743
19836242
8665853
19947936
18271526
25140053
15668240
22394513
17486068
33323455
32377695
22203672
17182860
12604776
14627991
15383614
23153581
15735736
28541302
16849543
17242169
20562913
32904620
9121472
15677445
7782294
16923119
17995934
19531499
15465819
31959764
32114396
23457600
29629558
18316398
23799367
24714105
31120930
12061819
16713569
7657591
33617900
10086340
19225046
33762435
23175185
16729043
28791635
16246327
28198003
15962011
22266821
15117950
27059931
10428778
12734385
8662998
25005938
27903975
16969069
26177020
8798643
10799548
9756944
15159412
19578043
15657067
18255265
23418353
25754235
22976291
17545148
12803489
18319245
19713535
7592693
30544639
15107835
11994282
17971399
16105874
15282549
20940296
23897813
9130710
18273061
18508924
17880946
20124286
12593795
16914641
20877636
10092522
25521828
11408594
22591401
9890970
20308550
22833562
21772844
33627783
11239464
|
HLA-DQA2
|
CD74
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
SH3GL2
|
CLEC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
DACT1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
DLGAP4
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
DNM2
|
DNM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TIAM2
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
DPPA4
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SH3GL1
|
DPYSL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SH3GL2
|
DPYSL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
EGFL6
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
EPHB2
|
ITSN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
12389031
|
SH3GL2
|
F13A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
FYN
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7499280
9344857
|
SH3GL2
|
GCH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
KIT
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17452978
10022833
17904548
12444928
7523381
10377264
24728074
16713569
8950973
7523859
8647802
|
MET
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9660480
11439336
8662889
19433454
15546961
11063574
7511210
21222362
|
GSTM3
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MET
|
HGF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18593464
20624990
19433454
22897854
8380735
15167892
16537482
17981115
28205554
17804794
28628118
1846706
18495663
1655405
|
HLA-DQA1
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DQA2
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DRA
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DRA
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DQA2
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DRA
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
ITSN1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SH3GL2
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAST2
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SH3GL2
|
PPP1R21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SH3GL2
|
PPP6R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
PRR14
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TIAM2
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SH3GL2
|
TYMS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SH3GL2
|
ZNF219
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ZNF219
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
AP2B1
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
DNM1
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
GRB2
|
WASL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
AP2A2
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
DNM2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
CBL
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.9
|
STRING
|
36370105
|
GRB2
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
11823423
|
AP1G1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
DNM1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHOSPHORYLATION
|
|
|
0.92
|
0.92
|
Signor
|
11726515
|
CBL
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
DNM1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
CBL
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
EPS15
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
SYNJ1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
33961781
21706016
7982917
9388224
28514442
11292345
|
PTPN23
|
STAM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
KIF4A
|
KIF4B
|
â—¼ CORRELATES
|
|
+
|
0.95
|
0.95
|
CCLE
|
31978347
|
SYNJ1
|
AMPH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
14704270
9341169
10542231
|
AP1G1
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
33961781
11409905
9733768
23415225
26344197
22939629
7593184
10535737
10747088
|
CBL
|
EGFR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16914641
7033849
028274
|
CD2AP
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
19380743
10339567
21988832
21706016
|
EPHB2
|
EFNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
33961781
28514442
26186194
11780069
|
EFNB2
|
EPHB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
AP1B1
|
AP1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
AP2A1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
AP1B1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
SH3KBP1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
6170483
15090612
|
CD2AP
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
22706086
15128873
25036637
17072306
25872741
12559036
11067845
33627783
12618476
12672817
17188587
17020880
|
FYN
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9677430
8621719
12244174
7782294
10629042
119942
7642581
15556646
12231245
9311917
9535867
8626543
10799548
16713569
16503409
10092522
8900205
8995358
25814554
9890970
15190072
15208330
12941616
10829062
11239464
8662998
17094785
|
EGFR
|
EGF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
25453753
30083275
21822280
12620237
19531499
25080504
12093292
22729867
23597562
18427122
26280537
18271526
10970856
15620700
11684674
21439278
8663535
28988771
2790960
10788520
10085134
16274239
25241761
17697999
9135143
12297050
|
LCP2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10224278
8695800
32296183
19380743
9565634
11314042
7706237
20936779
12176364
10204582
8995445
25416956
9716598
15929943
17235283
|
WASL
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
27107012
33961781
21706016
31980649
10781580
20936779
16713569
10087612
25416956
17474147
|
WASL
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11584276
18539136
|
AP2A1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
HGS
|
STAM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
NGF
|
NTRK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ARRB1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
GRB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16729043
5218694
|
AP2A2
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
EGF
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
CLTA
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
AP2A2
|
AMPH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
33961781
8552632
28514442
10748223
9280305
9195986
|
EPS15
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
10809762
18362181
8662627
9049247
26822536
19380743
|
AP2B1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
AP2A2
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
AP2B1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
AP2A2
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
AP2M1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
HGS
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CBL
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
IGHM
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
IGHM
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
IGHM
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
12453414
8306975
7524079
1702903
7927516
7592958
7688784
|
DACT1
|
DVL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21262972
16446366
25558878
|
ARRB1
|
DVL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
11742073
16713569
|
DVL2
|
LRRK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
20006983
19625296
|
DYRK1A
|
AMPH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
15262992
16733250
|
CLTA
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DQA1
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DRA
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CD74
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DPA1
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTC
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DQA2
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
DNM2
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
DNM2
|
AP1B1
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
AP1G1
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
AP1G1
|
CLTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
AP1G1
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
AP1G1
|
CD74
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
AP1G1
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
AP1G1
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
AP1G1
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
AP1G1
|
DNM2
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
AP2A1
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2A1
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2A1
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2A1
|
CD74
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2A1
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2A1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
12577067
|
AP2A2
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2A2
|
CD74
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2A2
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2A2
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2A2
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DQA1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DPA1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
CD74
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DQA2
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DRA
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DPA1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DRA
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
CD74
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DQA2
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DQA1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2M1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
23956138
31980649
24189400
19351721
20029029
24797263
|
HLA-DPA1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DQA2
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DQA1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
CD74
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DRA
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
MAPK1
|
ARRB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
19651622
19153083
18767875
17322306
15456867
10347142
20068231
19413330
9388255
|
EGFR
|
CALM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
17145710
19901323
20029029
12359306
16497976
25402006
17389395
18578522
16799092
20068231
3415247
7925415
18669648
12153558
24658140
17287340
14960328
18707149
17016520
|
STAM2
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
GRB2
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
25036637
25872741
8950973
917890
7642581
17944804
15210722
9108392
20936779
8695851
19836242
14725908
169092
28514442
9541596
9174058
11823423
12941616
10829062
10570290
7544353
11792427
8083187
15677445
8621719
9233773
9311917
23799367
16713569
10086340
9234717
8995358
25814554
9716598
11997436
7791764
8943292
8063801
8995445
8662998
11263968
16906159
8626404
9129019
98621719
17072306
9242692
10521482
9872323
8647120
7592693
9092538
10025673
17971399
17094785
9851874
11399323
33961781
9259313
18273061
7537740
8649804
9295052
11964172
9367879
20124286
10204582
19380743
9434624
21706016
8900205
9178909
12839496
9461587
31980649
11133830
33627783
8824292
8621483
|
HGS
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
EGF
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
17177598
16187797
15284455
16849543
16969069
16953218
17699773
17372273
17712310
|
CBL
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
GRB2
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10086337
10426994
10567412
10811803
10982827
11447289
11777939
11777960
11907067
12175651
12640133
15536084
15567848
15574420
16339513
16582911
16713974
16887996
17070508
17100878
17496910
17673906
18490724
19449109
26552706
8551221
|
SH3KBP1
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
20130058
20711168
12618476
11894095
16407834
16713569
11071869
19268472
25472714
17306257
22262777
15456872
11152963
10679202
15962011
25036637
15107835
22833562
11067845
11894096
12177062
17675467
21830225
12135478
24167568
16228008
12874286
17072306
15090612
14596919
|
FYN
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
97.0
|
1.0
|
Omnipath
|
9525940
7642581
8626543
7782294
15208330
16503409
16713569
10829062
10799548
10934191
8900205
8551236
8662998
8995358
19734451
12604776
9890970
10592173
17570479
10629042
17094785
10092522
11997497
12522270
15556646
12244174
8621719
9102067
22880054
9311917
11239464
19904769
11994282
12941616
9535867
25814554
12231245
15190072
|
CBL
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
188.0
|
1.0
|
Omnipath
|
34609770
16105874
18273061
22239438
24797263
20332299
17635922
23158001
17545148
8662998
12604776
9890970
23153581
17182860
25872741
12593795
23175185
10092522
15107835
22266821
22833562
24714105
17242169
25140053
20124286
19531499
9756944
10086340
22203672
19225046
16729043
15282549
20562913
22394513
20940296
23331499
7592693
19713535
10635327
19836242
15465819
15210722
25521828
23897813
10514377
12734385
18508924
11994282
20877636
33323455
22976291
23774213
23027125
15159412
18255265
16246327
28541302
16849543
23799367
16713569
10799548
8798643
19155296
9121472
17486068
21772844
16969069
15677445
15962011
23418353
12803489
32714745
14505571
27903975
19578043
26177020
11239464
18319245
11408594
10428778
12061819
17995934
17971399
27059931
26055326
15735736
23457600
7782294
22591401
29629558
11370743
7657591
21071413
28198003
18316398
19947936
9130710
18271526
15657067
31182136
16923119
17880946
32904620
15117950
14627991
15668240
15383614
|
CBL
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
16397241
15123609
23331499
25241761
21222362
11894096
18672314
21163258
19450681
18273061
35309168
17533376
19433454
17635922
10514377
|
CBL
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
9092574
17904548
25737303
8950973
15315962
17635922
10514377
|
CBL
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
158.0
|
1.0
|
Omnipath
|
11823423
8621483
9242692
18273061
17635922
16906159
8626404
8662998
9108392
9541596
98621719
9295052
25872741
17372273
8824292
8943292
12941616
20124286
19531499
10086340
8063801
9129019
9590251
11263968
9461587
7642581
10521482
10204582
8995445
8900205
7592693
9716598
8083187
14725908
17904548
7791764
9178909
25036637
8695851
19836242
7537740
15210722
9108316
169092
9311917
10514377
9092538
17072306
19380743
9872323
9234717
11997436
23799367
9434624
16713569
10829062
9367879
11964172
12839496
15677445
9851874
11792427
17094785
20936779
10570290
917890
17944804
25814554
17971399
11133830
8950973
21706016
8995358
9233773
10025673
8621719
11399323
9259313
9174058
8649804
|
CBL
|
RET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12727845
15677445
|
CD74
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CD74
|
CLTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CD74
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
CD74
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CD74
|
DNM2
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
HLA-DQA1
|
CLTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DQA2
|
CLTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DRA
|
CLTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTA
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTA
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTA
|
DNM2
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
HLA-DRA
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
DNM2
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DPA1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DQA2
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DQA1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
DNM2
|
CLTC
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
DYRK1A
|
DNM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17376771
15287745
|
GRB2
|
DNM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8402898
9009162
10206341
11877424
17244534
7505438
19380743
21706016
16713569
15834155
9452513
17474147
8119878
|
SYNJ1
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
Reactome
|
15260957
10542231
19575674
24966051
10535736
17765681
19536138
21316588
14622578
17158794
21779028
9428629
11082044
22099461
21445324
21613550
14622579
25107275
24581490
|
HLA-DRA
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DQA1
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DPA1
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
HLA-DQA2
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
DNM2
|
SH3GL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
16732277
16339507
25748042
17088212
29559111
17088211
9808461
|
HLA-DQA1
|
DNM2
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
HLA-DRA
|
DNM2
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
HLA-DQA2
|
DNM2
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
HLA-DPA1
|
DNM2
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
EFNB1
|
EPHB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
24003208
8878483
15114347
9576626
11114742
93308638878483
9330863
|
EFNB2
|
EPHB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
24003208
9267020
15114347
28719605
11114742
933086311780069
11780069
9330863
|
EGF
|
EGFR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
15003992
15175028
15466195
15958574
18423981
19631971
20430953
21098712
8101258
|
EGF
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17081983
19531499
17673906
10973965
|
EGF
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
131.0
|
1.0
|
Omnipath
|
17145710
17081983
21822280
20813200
23613900
9135143
25453753
21303971
10209155
26821125
12297050
27387652
25241761
30083275
12093292
30197274
21649524
19531499
18762250
16729043
26921391
17697999
17575160
21722395
12620237
19129184
10788520
23331499
3494473
15620700
14568001
15958209
24096486
18253097
16843263
18320059
21532939
10085134
22260327
15708576
26280537
23912460
21858221
11116185
10970856
27462018
18427122
25080504
20953304
19135477
11684674
8639530
27564112
18270696
2790960
17971399
23185569
19895983
28988771
29617357
23597562
19531623
23950932
21071413
8663535
6289330
16274239
17563729
21439278
20458382
22216880
18271526
12771140
21311755
24709886
25366117
12648462
21107857
|
EGFR
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
PDCD6IP
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
31980649
15456872
12771190
24658140
15557335
25402006
|
MAPK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
12556561
1651322
17081983
3138233
15901825
1939237
91332050
2543683
2115882
17192257
1651323
15302935
|
EGFR
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
109.0
|
1.0
|
Omnipath
|
9544989
10595738
23956138
27059931
10026169
16273093
11726515
24697349
21596750
19289468
7518560
21706016
23799367
9050991
16317285
16713569
25402006
11370743
24797263
8647858
8887653
9416834
21278786
16799092
8662998
10229072
11896612
7592693
19509291
8810325
24189400
19836242
11960376
7506413
18271526
15657067
10085134
24658140
17242169
7510700
8940013
7650032
8810340
11084343
12577067
7527043
31980649
11408594
19531499
20124286
23178716
9886492
23181695
9020117
8479540
14679214
12648464
1322798
17991782
16729043
17971399
|
EGFR
|
EPS15
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
17145710
17389395
10953014
24269888
19534553
25260758
19583965
19690332
15951569
9049247
17016520
|
EGFR
|
HGS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12953068
17016520
|
EPHB2
|
SYNJ1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15821731
23331499
|
HGF
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
MET
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
EPS15
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
EPS15
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
EPS15
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7797522
17474147
19109251
|
FYN
|
SH3KBP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
17350651
23052211
23506116
16529723
|
FYN
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
GRB2
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
FYN
|
LCP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10648627
9047237
|
FYN
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9038210
9799234
12374739
|
FYN
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16387660
17053785
|
HGS
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
STAM2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
GRB2
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
GRB2
|
LCP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10086337
10426994
10567412
10811803
10982827
11447289
11777939
11777960
11907067
12175651
12640133
15536084
15567848
15574420
16339513
16582911
16713974
16887996
17070508
17100878
17496910
17673906
18490724
19449109
26552706
8551221
|
MET
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9660480
15546961
22128289
12475979
11063574
7511210
11439336
8662889
|
KIT
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
24728074
8950973
7523381
10022833
7523859
8647802
16713569
17452978
17904548
10377264
|
NTRK1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11733534
10748052
|
RET
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9393871
16189514
15677445
|
LCP2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
7706237
20936779
10224278
8695800
17235283
15929943
25416956
19380743
9716598
32296183
10204582
11314042
8995445
|
GRB2
|
WASL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10087612
20936779
27107012
10781580
25416956
21706016
16713569
17474147
|
GRB2
|
KHDRBS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
10467411
20936779
21988832
7537265
9872323
8576157
11960376
11278465
9045636
21706016
16713569
12112020
7799925
|
HGS
|
HGF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
STAM2
|
HGF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
HGF
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
HGF
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11290563
12649206
15059978
16212809
17145802
18633355
19631971
20303741
22763439
23402812
23667593
26366398
26819959
27474009
28475121
9242465
|
HGF
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
57.0
|
1.0
|
Omnipath
|
17145710
22897854
15167892
1655405
20624990
19433454
23331499
17804794
1846706
28475121
22001117
16537482
15218027
27147579
24362531
17667909
16397249
20178463
17981115
28534512
8380735
18495663
14685170
|
HGS
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
HLA-DPA1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DQA1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DQA2
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DRA
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
ITCH
|
SH3GL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
14684745
17038327
26613292
|
MAPK1
|
KHDRBS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18691976
12478298
19664995
20068231
|
LRRK2
|
SH3GL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
25501810
24778241
22998870
|
RET
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
19901323
11522789
91184134
16156666
16497976
15592455
12571246
19415658
11826406
17389395
18578522
21109534
20068231
18452278
18669648
16153436
11522288
18691976
1378617
15972258
15935618
16094384
12388769
11971971
19651622
21842857
28450419
18707149
17016520
21455180
|
STAM2
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
MET
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
NGF
|
NTRK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
17145710
8155326
9083066
11729324
27908981
22666365
17404842
24224055
25611061
14985763
9290260
9857023
28090201
12067229
23772401
10490030
11114882
27229480
1706478
11738045
10713102
9547236
1849459
9775403
17409494
|
ROCK2
|
SH3GL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16164598
|
STAM
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
STAM2
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
STAM
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
STAM2
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|