Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NGF SQSTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11244088 10747026
COX5B COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
COX5B COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
NFYC NFYB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215853 12401788
ATP6V1H ETHE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CSNK2A1 CSNK2B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
COX7C COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
COX7C COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
SP3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18065760 15554904
JUN MAPK10 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
JUN CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11278771 16729332
JUN HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 20566634
JUN MAPK10 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19527717 7148309
DLD BCKDHA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2188967 10745006
CAV1 PRKAR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900527106 19706440
SP1 NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8961265
SP1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9875228
SP1 CERS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22169644
SP1 CYP2B6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20371701 8751713
SP3 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12637574 12888570
NR4A1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19213954 16873729
YWHAZ GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
EIF4G1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
EIF4G1 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10859165 5212678
HSPA8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CKMT1B YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
NFYC NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12857858 22969033
SP3 ALOX15B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14711820 15247906
SP3 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10811658 24219545
NR4A1 CYP11B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14645496 20097716
YWHAZ FASN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ECHS1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CTH YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
GID8 RANBP10 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
SP3 SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15247906 11517158 10825178 16734381 9329821 12414801 12200149 23825960
ATP6V0B ATP6V1H â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
NFYA JUN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11903046 21565167
GDNF MAEA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
GDNF ARMC8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
WDR26 ARMC8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27173435 29911972
ARMC8 MAEA â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
AANAT YWHAZ â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
MAEA WDR26 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31285494 27173435 29911972
ARMC8 MAEA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27173435 33961781 17467196 29911972
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
ATP6V0A2 ATP6V1F â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
MAEA RANBP10 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
ARMC8 RANBP10 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
AKR1C1 AKR1C3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PRKAR2A PRKAR2B â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SP1 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25879517 10506225 16713569 33572115 16478997 17215518
RMND5A WDR26 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
GID8 WDR26 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
NR3C1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15956716 15289446 16557033
NFYB NFYA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 25416956 12857729 23332751 26496610 14681455 8051128 26344197 15243141 15831478 17098936 16959611
SP3 CA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11672442 12615703
JUN NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 7823959 8733011
SP1 NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22609358 16135093 21123453
SP1 CA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8621466 22564704 21130740
SP1 ALOX15B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14711820 15247906
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
SP1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10849443 19027835
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
NR3C1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18174358 24500711 27371733
GAPDH NFYC â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAP2K4 MAPK10 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16186825 9162092 17875933
NR3C1 NR4A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR3C1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21900206 23331499 15591535
NFYA SP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16024108
SP3 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11368006 10618488 12440974
GID8 RMND5A â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ATP6V0B ATP6V1F â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
ARMC8 RANBP9 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
RANBP9 RMND5A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
GID8 MAEA â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
RANBP10 RMND5A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
RANBP9 WDR26 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ATP6V1B2 ATP6V1H â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
SP1 NFYA â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 30392062 10393239 15647279 10446910
ARMC8 GID8 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
ATP6V0B ATP6V1A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
RANBP10 WDR26 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
ATP6V1A ATP6V1F â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
COX5B COX6B1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
COX6B1 COX7C â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
GID8 RANBP9 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
COX5B COX7C â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
JUN MAPK10 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
MAEA RMND5A â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
GCH1 GCHFR â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
NFYC NFYB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 21988832 26496610 35140242 33961781 20936779 9388234 12401788 26344197
NFYC NFYA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 12857729 14681455 35140242 33961781 20936779 26186194 15243141 26344197 23332751
MAEA RANBP9 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ATP6V1A ATP6V1H â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CSNK2B CSNK2A1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 36833176
ATP6V1B2 ATP6V1F â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ATP6V1F ATP6V1H â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATP6V1A ATP6V1B2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
NFYA NFYB â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
DAD1 DDOST â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFYA NFYC â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFYB NFYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MAP2K4 MAPK12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11062067 19413330
SP1 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9762895 12736330 17012241
IL6 TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
SP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 23733894 12759366 27030318 22534375 7649977 12509451 12378384 15175554 18357389 10829018 11390427 17897957 18218727 8258705 12560487 17047073 21320120 7918637 16847329 10559188 18930140 20068037 1618817 21784970 10688670 10913190 17307735 18467438 21411747 11500175 20221720 20701940
SP3 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14555463 12759366 19109523 11390427 11500175
JUN TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 12759366 11087751 7935377 21059644 16881863 24548427 12509451 9826775 10318823 8998076 18408586 15546613 20164416 7896795 9211933 10952728 9566900 23583459 10748079 24009130 10954918 10754326 9813054 10837498 9988757 11739517 16365438 19285436 16199883 8816436 10551799 8552071 9160673 11490006 21098092 16483936 10688670 10913190 16888805 9030359 25567680 9760243
COX7C COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C COX5B â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
SP1 NFYB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18654640 9748295 9604010 18559965
CSNK2A1 CSNK2B â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SP1 CA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11672442 11429308 16270297 15184875 12615703
SP1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24019072 17023546 12576336 8756632 18793716 9503023
JUN IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20006311 22123848 14734615 15187132 11943142 20304822 17556653 1314139 17105733 22413812 19265145 11801649 16713974 7759501 12836278 15522880 12626576 9558063 8756632 18641343 22351517
JUN IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 26513016 10542237 21069809 15389813 15158360 20225236 12667961 20371366 20511231 20862675 8453101 10202034 18502099 10037779 8830832 19687301 21098092 25567680 20351184 17341596 11120852 21312239 24676671
NR3C1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19436110 8175711 27371733 11459775 8290595 21474440 2233715 1871124
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
NR3C1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20499359 8639160 2169353 9731701
JUN IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11306276 18566416 7935377 10226077 14686613 16365456 11145674 17283046 20463008 23608488 8133045 8798756 18789903 16729332
JUN CYP11A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11325530 11057754 17210646 7629150
JUN NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11905996 11733514 8717334 2111020
JUN NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18163434 19751824 16264271 20847229 7969116 8413214 10772826 10567637
CSNK2A1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 25609649 1846781 11948398 15378002 12531896 19413330 8654373 15302935 11075956 12628923 11896587 1516134 8464713 11971971 1651323 8137421 9685505 91332050
MAPK10 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17143273 20506250 16824735 8654373 20028971 16007099 21988832 12167088 16393692 1922387 16076903 22327296 19527717 21757544 19436832 17670986 14523011 11274345 20395206 11562357
NR4A1 NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8473354 23874817 8939459 7969116 9395454
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
SP1 NFYA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18654640 9748295 9604010 18559965
SP1 NFYC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18654640 9748295 9604010 18559965
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 CYP11A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10459866 10383457 20371701 9013760 12217897 10446912
SP1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9328340 8923463
SP1 NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19564345 12153142 10748033 16442295 23160377 12502798 10542271 9516473 22154511 12697323
SP1 ALOX12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16478997 9164849 18590721 10973489 20508969 14518567 16118214
SP1 CTH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22360859 22244329 16230075 21659522
CSNK2A1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9153193
HSPB1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19656944
NFYA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10393239 12427542 10446910
MAP2K4 MAPK10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 17143273 11489946 10748139 18408005 18855897 17761173 18083107 8974401 12788955 10715136 23331499 23047924 11062067 21614932 15911620 12738796 11389443 18988627 12624093 11847100 11242034 26370088 16076903 12133933 19651622 12354380 14523011 11274345
AHSA1 GCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 16696853
NR3C1 CYP2B6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14683479 11093784 12695351 19702527
NR3C1 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11216640 10329476 9694812
MAPK10 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12351702 18337589 9482836 9199329
GCHFR GCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16696853 8702680 11361142 17145710
MAPK10 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15071501