Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CAV1 CAVIN2 â—¼   COLOCALIZATION 2.0 0.8 intact 19262564 7234672
CAV1 CAVIN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001640 24013648
CAVIN2 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001640 24013648
CAVIN2 CAVIN3 â—¼   COLOCALIZATION 2.0 0.8 intact 19262564 7234672
CAVIN3 CAVIN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001640 24013648
CAVIN2 CAVIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001640 24013648
UBC PHB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7717349 20134482
CYCS PHB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PHB2 PHB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 PHB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7717349 20134482
CAV1 CAVIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001640 24013648
APP PLD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 PLD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731738 16407827
IGKC VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
NR3C1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18524938 17572486
ABCB1 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 15498565 5217256
TP53 ABCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10783169
FOXO3 ABCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18347152
TFRC ADCY5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VAPA ADCY6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALM1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
PRKACA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CUX1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14612449 22422878
FOXO3 AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10102273 5211323
PTPRF AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15896785
SMAD5 ANKRD13A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 ANXA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GRB2 ANXA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
PRKACA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2CA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAV1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPS1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SQSTM1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TARDBP APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CYCS APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CSNK2A1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TMSB4X APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAPN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12485888 5215996
APP TNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AR APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16987234
SMAD4 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12099698 15242331
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
NCOA2 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR CALM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16619263 20610535
AR KRT8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16046619
AR CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24218937 20610535
AR SORD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20372835
AR TMSB4X â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 17916567
AR NEDD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18703514
AR F2R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 15629896
AR MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14619959 20610535
AR NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887629 20610535
AR MCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 21525791
AR SMAD1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219486 17183365
AR FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18391971
AR F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15629896
TP53 ATF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TARDBP ATF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA ATF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATF3 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20565867 21467165
ATF3 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24420912 26554515
BAG2 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FAS BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15659383 25241761
BID CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9873064 9727491
BMI1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6948569 19233177
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
BMI1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 19903340 8291464
PTEN BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19903340
BMPR1A SMAD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19620713 11792802
BMX TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217965 16186805
BTK FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9880544 9751072
SP1 CALM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9348238 10945244
PDIA3 CAPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CAPN1 PTPN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 9407132 6732058
PRKACA CAPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11909964 29478550
CAPN1 F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10978167
CAPN2 PTPN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 9407132 6732058
PTPRF CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12176037 6731969
PTEN CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12176037 6731969
NOS3 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17502619 0611416104
TFDP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10684646
PTPN1 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
PTPN11 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
TXNRD1 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 7307565 19820694
CAV1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
CAV1 PTPN6 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
CAV1 TRAF2 â—¼   COLOCALIZATION 2.0 0.8 intact 5213300 11112773
PPARG CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21690289 12813462
CAV1 MMP14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15466865
CAV1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16890161
ESR1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20404154 17932106
CCL2 MMP14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15516694
MMP14 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11381077 21385940
MAPK1 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
CLTC TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CLTC TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PTEN CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12297295 11035045
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
PTPN1 CSNK2A1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6732073 9600099
CSNK2A1 RELA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5212888 10938077
TP53 CSNK2A2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CSNK2A2 PTEN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12297295 11035045
CSNK2A2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10938077
SUMO3 CTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20176810 20098713
SUMO2 CTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20176810 20098713
NCOA2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
SPRED1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14706452 18794899
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
PPP2CA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10644691 19061640
SQSTM1 CUL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15983046 22872865
KRT8 CUX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
E2F1 CUX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18347061
CUX1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10545217 12794834
CUX1 OCLN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20224295 19635798
GRK5 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24632620
FYN CYCS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CYCS PHB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CYCS SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10980706
VDAC2 CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9615439 16713569
GRB2 DBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15834155 5217666
VDAC2 DRD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GRB2 DYNLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
E2F2 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7958836
E2F1 HMGA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22389255
E2F1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18396012
E2F1 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20516113
E2F1 ETV4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687701
PTEN E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17218262
MAPK3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14967450 22802261
E2F1 MYCN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12438307 18319725
E2F1 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15867358 18319725
E2F1 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11857079 18319725
E2F1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15014447 18319725
E2F2 MYCN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12438307 18319725
TP53 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20428827
E2F3 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12110166 18319725
E2F3 MYCN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12438307 18319725
ESR1 NOS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17921256 0704315104
ESR1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19797124 20819530
ESR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16144913
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
ESR1 NQO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20623181
ESR1 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673088 7539106
ESR1 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673088 7539106
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14605097
ESR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16144913
ETV4 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7896795
ETV4 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14976186
SMAD4 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FASN EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EWSR1 HMGA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EWSR1 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
F2R MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
F2R MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
PPARG FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20416398 15644454
FYN FAS â—¼   COLOCALIZATION 2.0 0.8 intact 17159908 5219434
TP53 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9841917
MET FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28536399 15911745
HSP90AA1 FASN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
PPP2R1A FOXO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20110348 8288835
NR3C1 FOXO3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22848740
FOXO3 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17132628 16100571
FOXO3 ID1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17132628
FOXO3 SCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17522590
FOXO3 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16100571
SHC1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7516469 5220322
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
KDR FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
SP1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
WASL FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11340081 16525419
SNCA FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN VAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 11262396
HTR2C GJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
SP1 GJB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12850269 10760574
SP1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PPP2R1A GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
KDR GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
PTPN6 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10660620 6671678
GRB2 ITPR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SERPINH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 THRAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
HSP90AA1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18591668 21465483
MLC1 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPB1 PRPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 VDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18950704
SPRED1 ID1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD4 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19079362 12296825
IGF1R VAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11094073 17570479
IRAK1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218906 16884718
PDIA3 ITGA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
KRT8 ITPR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PHB2 ITPR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KCNA5 SUMO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0606702104 17261810
KCNA5 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0606702104 17261810
SP1 KCNN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12659870 20682843
PTPN11 KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9405464 19706677
VDAC2 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF11 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15531587 15024015
TP53 KRT8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8615594
TP53 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
MAPK1 LIMA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23188829
MAPK3 SQSTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7717053 20154642
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
MAPK3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16888388 16691505
PTPN11 MET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18579758 6731904
PTPN1 MET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18579758 6731904
SMAD4 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15339794
PTPN1 MET â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6764906 16537444
TP53 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
MLC1 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MLC1 PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RELA MMP14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19303700 21627988
MYCN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20145147
NCOA2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19805480 16483936
NCOA2 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11923473 23936147
SMAD5 NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBC NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
NR3C1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8569701 14630699
PPARG NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10848596
NOS3 SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD2 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17058229 12411395
NR3C2 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17376767 15199296
TP53 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
NR3C1 OCLN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18501346 18782596
NR3C1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16887915 19278840
NR3C2 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15044365 16960100
SP1 PDGFRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14593115 21289081
SERPINH1 PDIA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMAD2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21836474 21926264
TNF PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22078880 20651683
PPARG PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18309368
PPP2CA PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PPP2CA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24382322
PPP2CA SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20704570 23331499
TP53 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
PPP2R1A SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PPP2R1A PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
TARDBP PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPSAP1 PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PRPS1 VDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RELA PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14729949
PTEN SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12804776
TNFRSF1A PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11786908 6731384
PTPN11 VAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 12577067
PTPN6 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11786908 6731384
PTPN6 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8541543
SUMO3 RELA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25218447 22649547
SHC1 TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731794 17440088
SP1 SLC25A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18706393
SMAD9 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TGFBR1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511908 6798777
UBC SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
TGFBR2 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21358634 9679059
SMAD9 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TGFBR1 SMAD2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 10973958
SMAD9 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15231748
SMAD9 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD4 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
SMAD4 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12150994
SMAD9 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
TNFRSF1A SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12391233 20080539
TNF SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080539 0908486107
SQSTM1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TOLLIP SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2N SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO3 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11451954 17938407
SUMO2 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1004248107 20534433
TP53 TFDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574328 24096481
TP53 TMSB4X â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 TRAF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12788948 16969126
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
TP53 TRAF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12788948
UBC USP5 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBC USP5 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 7851534
VCP UBXN6 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
UBXN6 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PTEN USP7 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
FOXO3 TP53 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
GRB2 MET â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
PHB2 VDAC2 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
NEDD4 AKT1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 19953087 23195959 31390487
ESR1 TSC2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15039427 15851513
NEDD4 NTRK1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 16701206 27445338 21332718 19953087 25921289
UBC SQSTM1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5216530 12857745
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
BMI1 LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CAV1 VDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19595769 31980649
ESR1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 VAPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 FAS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
NEDD4 ISG15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18287095 18305167
SMAD1 NEDD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15231748 21308777
SMAD2 SMAD9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 15231748
CXCR4 ITCH â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
GJA1 NEDD4 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
TNFRSF1A TRAF2 â—¼   UP_REGULATES ✅ + 0.82 0.82 Signor 10795740
CAV1 BMX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11751885 16189514
MAPK3 HSPB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21575178 8774846 25241761
VDAC1 VDAC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31536960 22939629 29128334
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATF3 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CALM1 FAS â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CAV1 NOS3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HSP90AA1 KCNH2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NQO1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 NCOA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 0.83 0.83 Signor 11477071
CTNNB1 PPARG â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
TOLLIP UBC â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
NR3C1 RELA â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CD44 MET â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28205554 28628118 22897854
E2F1 E2F3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 24981860 20106982
GRB2 HSPB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31980649 12577067
E2F3 TFDP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
KDR PTPN6 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CAV1 TRPC1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
PLAA VCP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
HSPB1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CALM1 ESR1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
SMAD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11555647 20207742
MYCN SP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20697349 18003922 21123453
AKT1 PTEN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
SMAD4 SMAD5 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
AKT1 FAS â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25640309 31980649
AKT1 SMAD2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24412244 16362038
ARRB2 NEDD4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18544533 23208550
PPARG CAV1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12813462 21690289
FYN PTPRF â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12496362 31413325
LATS1 ITCH â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28416659 21212414 21383157 24107629 23564455 34079125
VAPA PHB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 26344197
VAPA VDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 26344197
AKT1 NOS3 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24379783
MAPK1 SHC1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
IVNS1ABP PRPSAP1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
USP5 UBC â—¼   CLEAVAGE ✅ + 0.86 0.86 Signor 26235645
ITCH LATS1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ESR1 FOXO3 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PPM1G USP7 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
PLD2 CAV1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 14675200 10675563
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DAG1 CAV1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11724572 34079125
PRPS1 PRPS2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PRPSAP1 PRPSAP2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SMAD5 SMAD4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10531362 16189514 15231748 16516194
VAPA VDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22939629 26496610 26344197
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
FYN CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 12640114
ESR1 PHB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CALM1 CSNK2A1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HDAC6 SQSTM1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PTGS2 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RELA SP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MAPK1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PTPN1 IGF1R â—¼   DEPHOSPHORYLATION ✅ - 0.87 0.87 Signor 11884589
AKT1 NOS3 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ARRB2 ITCH â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18544533 17947233
TRAF2 CAV1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11805080 32041822 16713569 11112773 16189514
KCNA3 CAV1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26931497 18218624 34196606
CAV1 PTPRF â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12176037 34079125
FYN CD44 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9573028 16189514 16713569
FOXO3 SMAD4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15084259 21532621
NEDD4 IGF1R â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18632619 12697834 18286479 19165858
SMAD2 SMAD1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 9111321 18729074
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
IGF1R SHC1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AKT1 TSC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12167664 15342917 12438239 12150915
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
CAV1 LRP6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16890161 28966723 34079125
CAV1 FLOT2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10212252 16189514 34079125
DAG1 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11724572 17474147
NTRK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10748052 11733534 25921289
HMGA1 SP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12665574 20335021
TRPC1 ITPR3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11290752 10980191 19052258
KCNA3 KCNA5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 18218624
SHC1 MET â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7731718 24728074 9660480
PPP2R1B PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8392071 8286818
SP1 SMAD4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10878024 18215124 11114293 21297662 22033265 16714330
TRAF2 UBE2N â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CALM1 SNCA â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ITCH UBC â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
NTRK1 SQSTM1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
IRAK1 TOLLIP â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
TNF TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
TP53 PHB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16918502 14500729 21829624
MYCN PHB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
AR PHB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22179832 16964284 18487222
PLD2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12824293 12890486 16049136
PLD2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12824293 12890486 16049136
IGKC PTPN6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23836650 7618087 9890995
CTNNB1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15592430 10987283 12154096
SP1 ABCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9865734 23765166
TP53 ABCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11483599 10792001 9865734
CALM1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
AR ALDH1A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 17526768
AR PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18386814 16317058
AR TSC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21036700 20610535
AR MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20610535 20946682 17283128
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
AR PTPN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22282656 20610535
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
RELA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16713569 8798655
CAPN1 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16998475
CAPN2 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16998475
E2F1 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15240700 12402042 15024076
E2F1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23796898 17360938 16582100
GNA11 BTK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9770463 11742120 9305846
CALM1 TRPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11983166 11290752 12601176
ESR1 CAPN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
TRPC1 CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19897728 19052258 10980191 12732636
CAV1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23634843 11563984 22230296 19595769
ETV4 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15138262 19483189 17390339
ESR1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12138116 18414489
CAV1 KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20462514 12529448 19923922
PPARG CCL2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 10432118 17681149 23390297
TP53 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22804246 23666675 20406462
PRKACA CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16785995
TGFBR1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12145287
SP1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10849443 19027835
MAPK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19941816
PTPN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12377785 17087658 9786960
CUX1 NTRK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23951412 16275928 10900073
CUX1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16144552 10229863 10868937
UTRN DAG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20625412 11430795 11430802
TPT1 DBN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
VCP DERL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 15215856
E2F1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24755270
E2F1 KCNA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12629508
SP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10547281 8657141 10850422
E2F3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15711575 12110166 18319725
E2F1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19276347 21625432
E2F2 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12438307
E2F3 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12438307
SP1 EDNRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16921166 16623715
SHC1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
ESR1 GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15028626 12810571 22962310
EWSR1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10749119 14534527 10508522
SP1 F2R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9494121 12975361
NR3C1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15802531 15590983 15289452
MAPK3 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19282669
SHC1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18385518 15930121
PRKACA FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20658524
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
PDGFRA GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
MET GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9660480 11439336 8662889 19433454 15546961 11063574 7511210 21222362
GRB2 TEK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11191051 7478529 10521483
GRK5 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19801552 2787365
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SQSTM1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12034707 10747026
ITCH OCLN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11782481 19478092
ITCH SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15350225 23331499
PRKACA LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21262972 18981475 21406690
PPP2CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK1 PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16231973 12459785 23109003
PPP2CA MAPK3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15930121
MAPK3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8197172
MAPK3 PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16231973 12459785 23109003
RELA MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19530226 20186924
SP1 MMP14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15592504 16716598 11013220
NEDD4 PTEN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SP1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7541039
RELA NQO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9058597
TP53 NQO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12149651 22154326 17077087
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
NR3C1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15956716 15289446 16557033
NR3C1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12734399 9261164 9442377
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
PPARG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NR3C1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
SP1 NTRK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19656944 19643914 21123453
PPARG TNF â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 10432118 17681149 23390297
SMAD1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23071089 12589053 16580992
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
PPP2CA TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17188031
PPP2CA SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21562258
PTEN SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10427092 21206972
TEK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14665640
SMAD2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18729074 9111321
SMAD2 TGFBR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SP1 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21421563
TP53 SUMO2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
TP53 SUMO3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
TP53 TPT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14623968 24067374 22157679
TP53 TSC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17409411 18431400
UBE2N TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18981220 14713952
VCP DERL1 â—¼   PHYSICAL_INTERACTION ✅ + 0.9 0.9 Signor 15215856
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
GRB2 WASL â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
DAG1 UTRN â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
DNM2 GRB2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
KDR SHC1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
E2F2 TFDP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HSP90AA1 NR3C1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
TNFRSF1A TRAF2 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
NEDD8 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
SQSTM1 UBC â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
GRB2 BTK â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 20936779 19380743
PRPS1 PRPSAP2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
PRPS2 PRPSAP2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
PSMD14 VCP â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
UBC VCP â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
PRPS1 PRPSAP1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
AKT1 FOXO3 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
VAV2 GRB2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 11606575 12577067
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PRPS2 PRPSAP1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
TFDP1 E2F1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
SMAD4 SMAD9 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
UBE2N ZNRF1 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
NCOA2 PPARG â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
UBXN6 VCP â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
IGF1R PTPN1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
DAG1 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10903901 17474147 7744812
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
CALM1 NOS2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PSMD14 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
NCOA2 ESR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12837248 17697320 11014206 12554772 18499756 15657427 11265755 9430642 11376110 9774463 16645043 9192892 11937504 26487511 12612084 19460354 20348541 11250900 12630920 12714702 14766010
WASL GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28514442 27107012 33961781 21706016 31980649 10781580 20936779 16713569 10087612 25416956 17474147
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
HDAC6 UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
NTRK1 SHC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
PLAA UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
AR NCOA2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
TGFBR1 TGFBR2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
BID MCL1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CALM1 NOS3 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
DERL1 VCP â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
NCOA2 NR3C1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
NEDD4 UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
UBC USP5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
E2F1 TFDP1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
ESR1 NCOA2 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12213123 8491186 8950973 9927207 9733714 8112292 10356320 11370743 32062451 8294403 16371368 22057045 9045692 9032244 8995379 7514169 9175774 9541596 8663178 7629070 9019162 7597091 7798267 9544989 9488479 8940013 10570290 15812354 11792427 8621719 24430869 7650032 11453982 16713569 7516467 10477741 8662733 11302736 26551075 9254595 7559490 12441060 8662998 8235613 12485888 28690151 16520382 8939605 11505033 9129019 11707405 15888547 8647288 7524086 25416956 24189400 11827484 12149229 8195171 21725358 9020193 10049786 9797459 9886492 33961781 9126968 8626525 7537740 12577067 11964172 12898421 8810340 22974441 19380743 9434624 10080542 9083103 21706016 15688026 7535773 31980649 8561895 7744881
PPP2R1A PPP2R1B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ATG12 ATG5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
UFD1L VCP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2CA PPP2R1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UBC UBE2N â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SMAD2 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TP53 PHB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24380853 16918502 20134482 14500729 16319068 16713569
PHB1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10523633 12065415 14637159
FYN PLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9837959 16713569 15282299 12697812
IGKC GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
IGKC FYN â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12453414 8306975 7524079 1702903 7927516 7592958 7688784
RELA ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18234965 21054339 19763573 12527911 22927901 10026303
TP53 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 1346476 18234965 8554604 8898977 10745175 19714248 9988237 10029407 11096091 11172607 11920581 17952118 8679460 9112432 11350951 8502478 11483599 7949467
SP1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18234965 7565762 10411657 23133566 10860921 9458366 17363581 7621073 8103518 10644769
CSNK2A1 ABCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22695718
FOXO3 AKT1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
AKT1 TSC2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10722653 10949026 11715018 11756412 11923280 15169778 15808505 16697215 17052453 17680028 18372248 18570873 18636226 20138985 20214616 20398329 20832730 9812896
AKT1 FOXO3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
PTEN AKT1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218262 17409395 19440036 19847259 19945467 20609352 21084277 22179046 22465479 23732914 24030100 24254977 25364523 26597054 27328425 27572739
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
RELA AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20186924 18031796 20649564
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
FOXO3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19424579 23517348 21752881 22539004 11278373
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
CSNK2A1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 29732088 17374729 21506126 11689703 10671551 12149249 15818404 10747897 10837139 20976471 19662498 21285348 11035045 11707428 21735093 17444818 20558317 11972058 16707567
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 19951971 11756412 11953455 11923280 20452955 21798082 20398329 21329882 10217147 11154281 11994454 23331499 10995739 19216069 20214616 11463845 21775285 20068231 9829964 17570479 10102273 18593906 17646672 16680151 18988627 21621563 15169778 17522590 25241761 23109003 11715018 19188143 15023346 17680028 26192618 11864996
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
AKT1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 23331499 17680028 20214616 17688959 20398329 16537363 17052453 19575820
AKT1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27997540 24291004
AKT1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19903340 15987703 10790335 20596030 10592173 20605778 10866658 12077256 11035045 16107342 12297295
AKT1 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17081983 18691976 11579209 16189514 10480872
AKT1 VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16551632 19335618 16027165
AKT1 PHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24522204 21689744 15173318
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320
AKT1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 12759249 20166139 11756412 10376603 11923280 12446767 16697215 11044445 20398329 18372248 11696579 16126727 16839566 15808505 20138985 20299462 10908731 20363286 11988487 11425855 20214616 23103584 11729179 16043647 17570479 12171920 25460366 27322328 11978735 15169778 11029403 25241761 19654415 10949026 18048761 11715018 12791703 24379783 18636226 9812896 23397142 17680028 10376602 12431978 10722653 20832730 18570873 25009123 17052453
AKT1 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12740362 11042204 19593530 22983196 17510053 23397142
AKT1 TSC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 75.0 1.0 Omnipath 16873412 12820960 17018601 11756412 32308763 11923280 16697215 19690332 21893193 20398329 18372248 21177249 12438239 18466115 15808505 29042482 20138985 15342917 17597835 20214616 12271141 16702951 20837138 17570479 26844273 15169778 17386266 10949026 16288292 24590173 11715018 15661536 18636226 18411301 20028854 9812896 16636147 20169078 17680028 12172553 19664994 18707149 10722653 12150915 18570873 20832730 12364343 17052453 18283331 21666717 27451907
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
RELA AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24466341 16619263 14576180 15517885 14715080
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
E2F1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21966451 17178887 22508987 21099110 21099103
FOXO3 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16061480 17522055 18687691
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR PRPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR NPEPPS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17409431 20610535 17721441
AR IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19318566 15033751 17202144 19250214 20610535
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
AR TNFRSF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR VAPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
HSPB1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19767773 17974989
NCOA2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9717843 12588987 15684378 14593076 24239470 15563469 18780293 12810069 16713569 10601285 14966121 10935543 10454556
MAPK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18511414 9725910 10318905
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
PTEN AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15205473 24480624
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
CSNK2A2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877451
CSNK2A1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11877451 32863206
PPP2CA ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
SMAD4 ATF3 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
SMAD4 ATF3 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
ATF3 ID1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16713975 16831886 17490644 18832382 21614932 23850759 9389648
SMAD4 ATF3 â—¼   UP_REGULATES ✅ + 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
TP53 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12386811 12372430 17108111 21927023 21394211
ATF3 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24317040 10964678 12161427 24951825 16688168
TP53 ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15933712 18431400 11792711 16169070 16713569
ATG5 ATG12 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
ATG5 ATG12 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
ATG12 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11825910 20562859 17145710 12890687 17353931 22342342 9759731 9852036 23202584 11265251 12207896 12482611
CAPN1 BID â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11404357 11940658 17264306 18469004 19931333
E2F1 BID â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12402042 15024076 15240700 15279786 17218262 17303408 17660363 18590585 7575488
CAPN2 BID â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11404357 11940658 17264306 18469004 21887410 23242420
TP53 BID â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12402042 16151013 18574470
CSNK2A1 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11583622 12598529 20356928
CAPN1 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18469004 12000759 20709625 17264306 21670566 11404357 21738214 16129881 17593948 16189514 21266584 11940658
TP53 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15240700 12402042 18431400 15024076
CAPN2 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18469004 12000759 20709625 17264306 21670566 11404357 21738214 16129881 17593948 21266584 11940658
CSNK2A2 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11583622
BMPR2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18756288 7791754 10712517
BMPR1A SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11438941 24412244 19620713 9136927 16189514 11792802
BTK BMX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12573241
IRAK1 BTK â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
SP1 BTK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11254710 11779634 7721790 10362515 8562928
BTK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20936779 19380743
CSNK2A1 CALM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 25108821 11827172 8206911 1520270 17173306 17329434 26675311 8639568
CALM1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10908731 19358819 10376602 10376603 20705923 22486744 12171920 16839566 24379783 11397791 11978735
PTPN1 CAPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9407132 12857726 19712109 8223493
CAPN1 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9407132 12857726 19712109 8223493
PRKACA CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11909964
MAPK1 CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11319218 14993287 10644690
MAPK3 CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11319218 26248159 14993287 10644690
CAPN2 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9470132 8223493 9407132
ESR1 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11773442 17535799 15033483 22031296 15496458
CAV1 TGFBR1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
CAV1 TGFBR2 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
TP53 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10684646 20610713 17014845 11076533
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
FYN CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9252391 29371975 11805080 12925753 21705803 12529448 11075810 15692085 14992595 8632005 10592173 16943184 12921535 16332692 12135605 20228056 15466865 33804982 24632723 33928090 18347068 34321069
PTPN1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 16388599 12176037 16189514
CAV1 PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 18988627 16189514 10066366
CAV1 TRPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14551243 10980191 16822931 19351713 18430726 19052258 12732636 19897728
TGFBR2 CCL2 â—¼   ENZYMATIC_REACTION ✅ 44.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
TGFBR1 CCL2 â—¼   ENZYMATIC_REACTION ✅ 44.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
SP1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10792620 10644332 17255531 8630731 10636866 16847329 10657660 23349788 12787135 12488502 12682245 25108845 8051410
PPARG CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16155367 17255125 20663893 15659119 15531761 20473515 18226310 18060855 12110006 20508203 11606585 10930382 16105976
RELA CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 24337575 10644332 22189654 18226221 20038977 8630731 12488502 19738286 22189669 14976218 19371341 12540607 24260304 11716760 21138578 8617886 12218154 14631383 20952659 17452470 16325549 10744656 15223809 10530453 11006087 16040075 16730843 23583295 24063814 27076634 10987310 16206198 9388261 10614622 18353872 16166627 16829531 16818736 10636866 20195282 10469356 17507908 12647268 12682245 21106671 24550391 16764699 17932106 25108845 20200316 15950427 24634218 9174597 23198981 11949945 9916692 17537731 22723832
CTNNB1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18483247 12782598 17724465 10027409
SP1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11316768 15111490 21193408 12972613 16943418 18372343 18596044 10976926 12091390 12943729
DNM2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 CLTC â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
CSNK2A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12700239 12432063
CSNK2A1 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10852916 11813001 10617630 14645218
CSNK2A1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 34049972 15016307 10938077 27630163
CSNK2A1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 16107342 33760042 18723495 25823029 21840932 10866658 24766807 16690621 21779440 24706748 19662498 28263967 15987703 11035045 12077256 24047694 11707428 22413754 17444818 26832662 12297295
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
CSNK2A1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9153193
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
CSNK2A2 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17444818 19662498 15987703 16107342 11035045 12077256 11707428 12297295
CSNK2A2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12700239 19141652 12432063
CSNK2A2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16083285 1088347 10348343 10884347 16552184 9315650 10747897
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
PPARG CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12021175 15190077 20303941 14764597 19075513
CTNNB1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11396184 15592796 12154096 17945188
PTPRF CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10187801 9245795 11245482 12095414
MET CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17496910 25163657 24511551 22558232 11929826 16909210 24342833 12040186 26654598 19568798 14585353 23083465
LRP6 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 25088803 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
FYN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 20026641 22264731 24511551 25241761 22340496 12640114 25803041 26509276
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
IGF1R CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17496910 22558232 12040186 19568798 14585353
CTNNB1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 15905404 21071413 17254970
CTNNB1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25721714 16847334 25168821 19495794
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
SQSTM1 CUL3 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 14744430 15340068 16252010 18545270 19427028 20531300 21981924 25002027 26587781 28574505
RELA CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20068066 12690099 16267013 20157762
ITCH CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28264927 19116316 24489825
E2F3 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14576826 7958836 12063292
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
TP53 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21715977 20805247 8557038 11795482 17210690 22952705
SP1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9054613 12697671 10446910 18440323
E2F1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15711575 12110166 20971808
E2F1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12438307 16931907 14645238
E2F1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22241525 8557038 15706352 21441950 12675512 23954287 12625370
E2F1 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 20211142 15133492 22327218 7892279 16360038 9199321 8405995 9704927 8816798 9780002 8657117 9464260 22629304 7739537 27705803 25368385 9501179 8816502 8832394
E2F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22480684 11739724 12625370
E2F2 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20211142 8657117 8755520 16189514 7739537 8832394
E2F3 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8755520 7739537 8657117 8832394
FOXO3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24062311 16807346 16809346 17575143
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
ESR1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22052999 11029009 10690351 14742696 19914929
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
ESR1 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16574784 18006642
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
ESR1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15833836 10960840 11174852 8923463
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
FOXO3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11435445 15367686 16807346 18312651
PHB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15140878 17932104 26052702 10938099 12943695
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
ESR1 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18499756 9192892 9430642 11014206 19460354 15657427 23331499 11477071 26487511 16645043 12612084 20348541 12630920 14766010 17697320 11937504 12714702 12554772 9774463
ETV4 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11901151 24983502 21150337 11274170
SP1 F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12483323 8576248 15636197 7615158 10707957 9081693 7876129 10551840 9198250
RELA F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15242552 11057875 12746898 9867853 18226221 19167713 7615158 7929355 9081693 11157486
SMAD4 FAP â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
TRAF2 FAS â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TRAF2 FAS â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
SQSTM1 FAS â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 12702723 15340068 16252010 16498403 20531300 21981924 23069999 25002027 26587781 28574505 9184224
TRAF2 FAS â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TP53 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10101800 12788915 15580300 16317104 16322229 14719118 16557594 20797428 11103825 19615968 7539102 12447615 12944915 12963547 11313989 16951143 9841917
MLXIPL FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20416398 16800817 15496471
SP1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10022897 9261184 22084312 9300785 10871852
MLXIPL FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17716660 21453770 22382520 20100709
TP53 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12734185 19861536
PPP2CA FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19029949 15207915 20110348 17322870
MAPK1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18204439 29445193 22128155 10102273
FYN PTPN11 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10591186 10648627 12218089 12731048 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
KDR FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SHC1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FYN PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10212213 11157475 16713569
FYN PTPRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12496362 18854310
FYN SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12893833 11162638 11744621 28671665 17570479 16713569 24860424 11078745 12096713
FYN SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 96.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 16713569 9446569 17389395 23331499 18578522 10921922 10482988 10764799 18452278 20068231 10592173 18669648 12522270 9685404 10896916 7516469 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
FYN ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16387660 17053785
SP1 GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11255234 19339281 10421804 18513187 16652385 19679555 22549838
MAPK3 GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 9535909 19664994 9535905 12637502 15605363 8631994 17570479
MAPK1 GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 22028470 9535909 19664994 9535905 12637502 15605363 8631994 17570479
IRAK1 GLIPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25544559 26678074
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 KDR â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 KDR â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
PTEN GRB2 â—¼   REGULATES ✅ 15.0 1.0 ACSN 10648629 10753747 11747822 12040186 15584861 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523
MET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9660480 15546961 22128289 12475979 11063574 7511210 11439336 8662889
KDR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9405464 16966330 10319320
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
PTEN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
GRB2 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10087612 20936779 27107012 10781580 25416956 21706016 16713569 17474147
GRB2 VAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 19531499 7809090 11606575 12577067
GRK5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 27326393 15053879 22223642 20124405 26029824 26226012
GRK5 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 25915624 10852916 11813001 10617630 26614013 16957079
MAPK3 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24089523
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
HMGA1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10085153 18279675 11056164 14630716 18937643
HSP90AA1 SHC1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 16187797 15284455 17646646 16969069 17372273 17712310
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 16131566 8089152 10903152 26804907 31467278 8645634 15916966 24949977 21511880 19875381 9334248 12093808 16189514 20195357 24462205 10066374 14987994 8898375 8621522 8139547
HSP90AA1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12124224 11988487 11425855 11744239 9580552 12676772
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
SP1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9328340 8923463
HSPB1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19656944
HSPB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25241761 16169070 16713569 17184779
SMAD4 ID1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16713975 16831886 17490644 18832382 21614932 23850759 9389648
SP1 ID1 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
SMAD1 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18381431 15331632 20522807 12296825
SMAD4 ID1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9389648 18832382 16831886 11074002 17490644
IGF1R SHC1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 16931767 17145802 19030972 21540285 24103846 24782617
SP1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10720440 21447702 7497000 15345673 17170218 7491107 17049831 17014845 10982795 17486080
TP53 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15131018 11001824 12089352 20633551 24205274 17097318 10023442 17600529 17014845 8710868 12444079 16181796 22033326
PTPN1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 11884589 15976035 8702689 16926280 8999839
NEDD4 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 18988627 12697834 19165858
PTPN11 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28065597 23331499 11779860 7642582 10082579 8895367
PTEN IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
IGF1R SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12767520 15629149 7541045 17145710 8776723 7559507 14764897 17570479 16113100 24051437 17673906
TOLLIP IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 26673132 11751856 19716405 21903422 14751757 16024789 17276401 10854325 16713569 17635639 15388348
PRKACA KCNH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10837251 19651622 18791070 10488078 11953308
SHC1 KDR â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SHC1 KDR â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SP1 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19888537 14684628 15111490 12560084 19469899 21980525 16678129 18006642 9079666 12067897 21430706 16574784
PTPN6 KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9405464 16453023 18377662 16337972 18840653
KDR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10749680 9405464 11950700
MAPK3 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17496910 18039929 19541618 21965663 20974802 19565474 15547943 12063245 12738796 11226259
MAPK1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17496910 18039929 19541618 21965663 20974802 19565474 15547943 12063245 12738796 11226259
MAPK1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
SP1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12220517 16797880 20506264 20121399 20882567 18372343 10727414 21170990 17889508
SNCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11279280 12121974
PPP2CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 10592173 7780739 18588945 2154696 20626350
SHC1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10996427 23584453
MAPK1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 25409419 11733495 16574647 9099735 9030579 15507114 26670611 17570479 17998334 18596912
MAPK1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12351702 18669648 9199329
MAPK1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15073167 16888388 16691505
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12801888
MAPK1 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12223490 18220336 15241487 25324174 16543145 18676833
MAPK1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17289590 19914168 9335504 19914161
MAPK1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 10197981 34504019 18775330 20659902 8226933 9620846 16156666 9604935 18988627 12193595 11027280 8388392 27153775 31995604
MAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 14965474 9765199 15116093 21675959 23443559 10781582 25241761 10446957 10958792 11409876 11709713 21147777 10673501 11551930 15867353 11875057 12091386
MAPK1 TNFRSF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10702263 11606045
MAPK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19318349 20882567 16377629 18775330 8226933 14744793 16079281 11904305 9604935 15212693 14593115 8388392
MAPK1 TSC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15342917 15851026 18794886
MAPK3 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
PPP2CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 18588945
MAPK3 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12351702 17440046 9199329 20047289
MAPK3 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17081983 16156666 19413330 11027280 9620846 33676893 23331499 8226933 20068231 18988627 12193595 18491316 18691976 8388392 19651622 10197981 18775330 19115199 9604935 15212693
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15241487 21507240 25324174 16543145 18676833
MAPK3 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17804409
MAPK3 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 10197981 9335504
MAPK3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28115363 12801888
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
MAPK3 TSC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15342917 16244323 15851026 18794886 19188143
MAPK3 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18596912 11733495
TRAF2 MCL1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
TRAF2 MCL1 â—¼   SHARES_COMPLEX 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
TRAF2 MCL1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
RELA MCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22496479 19303700 24529193 18761050 18223231
SP1 MCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22406829 18599869 17198743 22734486 18208354 23877711
TP53 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11160159 19808698 11832478 18208354
SP1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11910354 12473536 9223667 15067326 21831840 17283128
PTPN1 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18579758 16537444 22789536 18819921
MET SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9083103 11687594 9660480 14990987 24728074 8084588 8939605 8947042 7731718 11884620 15688026 14685170
SP1 MMP14 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
SP1 MMP14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15592504 18927121 23394613 17534446 14979875 12093818 10721699 18568943
SP1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14567977 22815527 21123453 14645238
MYCN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20811720 11107122 10050884 21862876 20145147 19885598
NCOA2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 11500849 9238002 17513608 21071413 15026545 18988627 18584035 10944516
NCOA2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11266503 29170386 12151000 9920895 9590696
NEDD4 PTEN â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 17218260 17218261 17996703 18562292 19652529 22679284
NEDD4 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17218261 23331499 21071413 18307411 17218260 18562292 18498243 19345329 19652529 30594392
RELA NOS2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14668329 15079071 15536066 17145890 17404308 17550372 19171876 20138012 23430059 8383323 8580069 9743347
SMAD2 NOS2 â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 21042762 21614932 22331441 23390297 6357187 8871614 9389648 9670020
SMAD4 NOS2 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 6357187 8515656 8871614 9389648
PPARG NOS2 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
TP53 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11131279 11092782 9194524 8637893
PPARG NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15950726 11595817 19997048 10848596
RELA NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 23085209 17720813 12057007 15350552 17068060 20600530 18596035 24360823 11036073 10085153 16318585 24014650 17035338 16169848 9754583 14978160 16283237 19766095 15170030 9712833 18057724 9685183 17081374 17041221
RELA NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18397880 14570928 17081374
SP1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12759366 19105596 15722551 18624763 12684688 9614091 10574932 10713142 15061658 12270858 15180995
PPARG NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15590897 19666848 19732722 16020752
PRKACA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15319357 12522122 34204249 10376603 31923467 16839566 33429979 34026871 16946136 10908731 10671564 16270749 11729179 12171920 26132171 11978735 17572401 24379783 10376602 16873402
NR3C1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24811171 27777311 10649448 8754811 11279134
NR3C1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10631313 18945810 10827178 18657608 9918831 19797430 10701683 18650268 16198345
RELA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
NR3C2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NR3C1 NR3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NR3C1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
PTPN6 NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14662744 15557341
SQSTM1 NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 18457658 12471037 10747026 11244088 18174161
NTRK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 8155326 9715270 8226808 15056278 10708759 8552402 9856458 23331499 10629055 10092678 12446789 8524391 25921289 7541035 8183561
PDGFRA SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15592455 9121430 9446569 12767520 10921922 10482988 10764799 17673906 17496910 12522270 9685404 10896916 9927207 8702728 12237775 8610109 9741627 9710204 10816433 11075717
SMAD4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 16580992 12524424
PPARG PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18065496 16775433 16425225 23867870 20198337 11378386
PPARG TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20376096 11009565 14646597 20473515 11124825 17532302 17464333 19031802 14656714
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
PPARG PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11278336 16506021 19578162 20234816 10827178 14555539 11412039 19997048 20656057
SP1 PPP2CA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19750005 19420015 12076969 21420382
PPP2R1B PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18715871 17540176 19114990
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11591705 12842894 17188031
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
PRKACA RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
SP1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12759366 16574895 16790435 9458366 9415398 12169688 10949931 12694408 11562358
PRKACA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11931769 15833743 9150141 17959673 9660950 16135789 12628924
PRKACA TFAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23201127
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
SP1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16840740 17616668 17012241 15767339 23635401 10825178
RELA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16001969 9266823 19783677 12471036 17673602 10827178 16210649 20669087 12466023 15517885 15013753 12622742 20600530 14645117 18294142 19618291 12067569 15655349 17556653 18973191 14988266 12871860 20103608 19284764 15555528 21149600 11082190 15234907 9041934 22001128 16820889 18752821 19766095 15997464 8995303 9710122 12349897 15387324 15368354 18057724 15547942 16624933 17767925
TP53 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21187340 16713569 11687965 21763744
PTPN11 PTPN6 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPN11 PTPN6 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPN11 TNF â—¼   DOWN_REGULATES ✅ - 26.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 17307799 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 27557510 9751747
SP1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7636984 8450395 9151857 20538607 11964305
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
RELA TRAF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15041463 19392652 21573233 15723831 9733516
RELA TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 136.0 1.0 Omnipath 26596471 17707233 20817730 12686724 27075886 21765477 21537341 19530226 17390058 18077329 15064230 20617556 8805669 17351769 23335080 21573233 17292554 16285952 9916895 11749970 7895918 17496784 12628924 23857586 12657243 15857826 12471036 11259437 16433741 9831247 20237317 15465827 26023919 22661093 10748079 15013838 17350185 10754326 15470505 11827962 20139176 26408955 22901690 18772140 21108432 22742857 23195252 18362169 24012417 11312646 17442180 9281604 10079106 11297551 15081318 22718766 24908318 8219230 26004152 11094063 11490006 9916692 16483936 18057724 16569682 22138107 18467438 20547752 22723832 19846753 17407192 20221401 19854828 20534538 7876168 16707469 12117498 20544543 23178569 15812247 21138578 12610112 25888873 16916598 16040075 28039105 14749357 20066113 19285436 25161822 22388040 14960579 20195282 16199883 15543947 23971673 10551799 11290773 22798670 22021035 20722069 20221720 27338466 19385047 12058956 26997758 25690886 7624137 20686703 26114754 14976218 10485496 17607667 8622636 11007957 18285351 10837498 11739517 18719026 17268554 17085785 17142966 10963848 9742085 23042817 27534992 10553096 26516703 20696864 10201927 16850160 8679226 21098092 20097764 9129150 17082635
TNF RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 15192014 27329558 22240205 15833743 19351843 28187781 15841081 28107185 28373828 26999213 24386331 24957606 26179215 21572963 18258304 28317833 29441018 10722927 19596989 28423685 12881425 25118327 24036851 28089769 21904602 24141032 10938077 30201812 20691659 24166907 19789307 19393267 22768286 26310932 19411070 23789107 28790310 29708974 20507904
RELA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12055073 7933095 10671503 20861353
TGFBR1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12767520 22710166 23331499 19010789 16474430 19920116 22943793 17934056 20519943 12809600 21900405 11133108 14557817 15548370 17673906
TGFBR2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12767520 22710166 19010789 16474430 19920116 22943793 17934056 20519943 12809600 21900405 11133108 14557817 15548370 17673906
TGFBR1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19651622 9748228 9335504 10085121 9136927 15212693
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
SMAD4 SMAD2 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD2 SP1 â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
SMAD2 SP1 â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
TGFBR2 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
TGFBR1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
SMAD2 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16052471 11376804 11456453 9812998
TGFBR2 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10678166 9463378 11792802 11133108 19920116 14557817 11278410 15178549 20060931 17934056 21614932 8980228 9311995 20519943 21900405 15548370 19010789 15104092 16474430 30093905 11274345 9865696
TGFBR1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 10678166 12220225 9892009 9463378 16024789 9136927 14625308 11792802 11133108 19920116 14557817 11278410 15134444 10085140 23331499 21071413 20060931 17934056 18511908 21614932 18988627 10973958 23221174 8980228 9311995 9346908 9235954 20519943 21900405 15350225 15548370 26057631 19010789 15104092 16474430 9346966 30093905 12957874 11744690 9525694 15212693 11274345 9865696
SMAD2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 15613484 17145710 25609649 15817471 20211142 21532621 24584437 18729074 23788427 12419246 16916642 9288972 9892009 21454478 17510063 10531362 15231748 11027280 12167862 21988832 9389648 23331499 12543979 18568018 21071413 19135894 18511908 15467747 12808092 11927552 25514493 15350224 18988627 12732634 10878024 9111321 9311995 9346908 10199400 11264182 12957874 11114293 15761153 11274206 12621041 17272273 24157709 26555259 12374795 22442258 10781087 15922743 11102446 17591701 18783722 16751102 19139564 19917253 9346966 21297662 17283070 12794086
SMAD2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19558215 10878024 12631740 11013220 11114293
SMAD4 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
TGFBR2 SMAD4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
TGFBR1 SMAD4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
SMAD4 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD5 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20957627 23331499 14534577 16516194 16189514 10531362 15231748
TGFBR1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8774881 20060931 11274345 21614932
TGFBR2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8774881 20060931 11274345 21614932
SMAD9 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20957627 25502805 10583507 31515488 16189514 15231748
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
SP1 UTRN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11237613 15172107 11997063 10871758
SP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 23733894 12759366 27030318 22534375 7649977 12509451 12378384 15175554 18357389 10829018 11390427 17897957 18218727 8258705 12560487 17047073 21320120 7918637 16847329 10559188 18930140 20068037 1618817 21784970 10688670 10913190 17307735 18467438 21411747 11500175 20221720 20701940
SP1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18053089 11507078 22028617 15647279 11687969 10982796 12750289 15895377 10766860 9632722 15905358
SP1 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9762895 12736330 17012241
SP1 UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19733223 17409431 11872750
TGFBR2 TGFBR1 â—¼   PHYSICAL_INTERACTION 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFBR2 TGFBR1 â—¼   SHARES_COMPLEX 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFBR2 TGFBR1 â—¼   ENZYMATIC_REACTION ✅ 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFBR2 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 7774578 9463378 19556242 8047140 23868260 18243111 7890683 10026191 23331499 8576253 21071413 7878020 21791611 10716993 18988627 11278251 19758997 25825445 22802914 16446785 11483955 8947046 11323414 11124802 15221015 11102446 11387212 12809600 7566156 26194464
TRAF2 TNF â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNF TNFRSF1A â—¼   PHYSICAL_INTERACTION 33.0 1.0 ACSN 11112697 11274345 11279185 12531547 12646658 1330325 1431106 14607933 14625680 15099563 15310755 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 21920725 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 26801188 28765050 8663014 8910423
TRAF2 TNF â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TNF â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNF TNFRSF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 98.0 1.0 Omnipath 17145710 19084540 8288897 11448951 23746843 22801493 14732063 2848815 9568681 2158863 8182064 9488135 23070005 20080539 11239407 26670046 14743216 21724995 21133840 24070898 25911380 7852363 2170974 17151142 26186194 27560715 25241761 23032187 24726327 20103630 8805640 11502070 19442713 3034874 23955153 18067990 22099304 15485837 22675546 12753742 1310388 12887920 19287455 10634209 2170559 1331108 24980434 22028622
TRAF2 TNFRSF1A â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TNFRSF1A TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 26212014 8565075 8943045 8612133 16713569 16611992 22179575 11821416 7544915 12721308 21741934 10795740 21119000 19150425 27321185 25241761 15115707 18776134 15743837 15485837 20448643 12887920 24735611 20333651 18022363 19815541
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
USP5 UBC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 19285159 20622874 22878415 26235645 18482987 19373254 16007098 31663737 25970461 27848959 17550899 26876099 24681967 23314748 17980597 16564012 27066941 17692280 22428841 8841133 22216260 24424410 34648286
TP53 KDR â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
TP53 ALDH1A3 â—¼   KO_DOWN_REGULATES ✅ - -1.28 1.27 PKG 28854368