Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FGF9 FGF10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 8663044
FGF19 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16844695 10652257
FGF19 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15863030 11353842
GATA6 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19501129 17463088
CANX SMURF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMURF2 TGFBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 15221015
ATF4 FGF21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22233381
CALM2 CALM3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CALM1 CALM3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PDGFRA CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730895 9546424
CRKL ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
CALM1 CALM2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PIK3R1 SOS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS2 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS2 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
EGFR ERBIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23220880 22908275
ZFYVE9 ERBIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
EGF ERBIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23220880 22908275
CALM1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
ERBB3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17308105
IGF1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19183465 12875741
OCRL APPL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8184127 21378754
SP1 ASCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20599619 17728141
SOX10 ASCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12691661
ATF4 PDGFRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20617572 19648113
PDGFRB BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
PDGFB BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
PTK2 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221628 9285683
PEAK1 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0914776107 20534451
PDGFRA BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
ITGB3 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16581250 8649368
PDGFA BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
BCAR1 PEAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0914776107 20534451
TNK2 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16247015 17038317
BCAR1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27447856 10799562
BCAR1 RAPGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9748234
SP1 CALM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9348238 10945244
CFTR CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12208510 5215704
HRAS CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621645 5220985
PLCG1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
STIM1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0905002106 19897728
PTEN CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12176037 6731969
RASA1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731661 15504032
CAV1 STIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0905002106 19897728
FOXO1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20082134 18444242
PTPN11 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
CAV1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
FOXO1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18444242
PPARG CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21690289 12813462
INS CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28601906 25748795
CAV1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15976327
PDGFRB CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731806 17620338
ITCH CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12226085 5215735
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
CBL PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBL PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBL PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBL ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
SRC CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17094785 7033811
GORASP2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NCK2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GRB2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CBLB â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CBLB PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLB PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
ITCH CBLC â—¼   COLOCALIZATION 2.0 0.8 intact 12226085 5215735
CBLC ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CRK CDH11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CEBPB HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9315634 9212164
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
CEBPG PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10862621 12524424
STAT1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19061877
CREB1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17464208 18471910
CREB1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20629536 10567368
CREB1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10909971 22554507
PDGFRB CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10733900 6731185
RAPGEF1 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621483 5220979
ERBB3 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
CRK SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15834155 5217666
GRB2 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
HRAS EGF â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
KRAS EGF â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
NRAS EGF â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGF PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 19531499
EGF SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499 17673906
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
STAT3 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731598 14966128
EGFR NRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR KRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
SP3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20435036 20407012
STAT1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10558875 22693070
PTPRG EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
EGFR PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 1845983
PTK2 EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19948216 10655584
EPHA2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 7982920
GRB2 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
RASA1 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
SRC ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB3 NCK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB3 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB3 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
ERBB3 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 17496910
ERBB3 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 17496910
ERBB3 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 17496910
ERBB3 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 17496910
ERBB3 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273093
FGF2 FGF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18552176 18757403
FGF2 FGF9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18552176 18757403
SP1 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15158147 19302822
PLCG1 FGF23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16844695 10652257
PIK3CA FGF23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15863030 11353842
GATA4 FGF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10358083 15082719
FGF6 FGF9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18552176 18757403
POU5F1 FGF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21083502 21621531
FOXO1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22968147 21335550
FOXO1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16670091 19289458
FOXO1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25510553 19049975
GATA4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19501129 17975667
YY1 GNAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18458536
GORASP2 GOLGB1 â—¼   COLOCALIZATION 2.0 0.8 intact 20608975 7897361
SP1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PAX3 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3CA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRMT5 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 MYO6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PRMT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MYO1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
SRC HGF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17574028 20802513
HGF RAPGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10753869 12006644
HGF PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10871282 10648629
HGF STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9094433 9440692
HGF PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10871282 10648629
HGF PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521801 16782899
STAM2 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS NEDD4 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 12230472 5215741
STIM1 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RASA1 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221569 9219684
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
HRAS STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PTPN11 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
HRAS PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9069260 21779497
ITGB3 PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731544 12791772
JAK1 STAM2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10993906 5213009
PTPRG KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
KIT PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 7520444
SP1 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887648 19994725
PTPN11 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
SP1 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PAX3 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PDGFRB NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730458 7692233
TNK2 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217936 16137687
NCK1 RAPGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCK1 PIK3CD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PDGFRB NCK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11027258 6731249
NCK2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 11557983
PTPN11 NRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
PAX1 PDGFRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9826722
SRC PAX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP1 PAX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20435036 18314536
PAX3 PDGFRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10411402 9632796
PDGFA RAPGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
PDGFA PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7691811 9739761
SP3 PDGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15297375 9321833
PDGFB RAPGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
PDGFB PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7691811 9739761
STAT3 PDGFB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7876144 8662928
PDGFB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15845350 12753909
SP1 PDGFC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15247255
SP1 PDGFD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189269 18258854
PDGFRA RAPGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
SP1 PDGFRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14593115 21289081
SOX10 PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18184726
PTPRG PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25624455
PTEN PDGFRB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16456542 5218301
SLC9A3R1 PDGFRB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16456542 5218301
PDGFRB RAPGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
PDGFRB PIK3R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730293 1330535
PDGFRB STAT3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 17145802 17496910
PTPRG PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
PDGFRB PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 11172806
PDGFRB PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 8702949
PDGFRB STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 9484840
STAT3 PGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23042533
PIK3CD PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
PIK3CA PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
PIK3CD PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
PIK3R2 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8596638 11733063
PLCG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
PIK3R1 RAPGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25814554 15021914
PIK3R2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499 9651378
VEGFA PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11387210 11600407
RASA1 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
SEC24B PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG1 PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
RASA1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9020117 9743338
PTEN SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12804776
VEGFA PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15026417 9182576
SRC PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
PTPRG PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
STAT1 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 10022928 18508557
PTPN11 SRC â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
PTPRG SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
PTPRG STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25624455
PTPRG STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25624455
SOS1 RAPGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
RAPGEF1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
VEGFA SHC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10749680 12214271
SOS1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP1 SPHK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17555548 16135093
SP1 YY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22553354
SP1 VEGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19147754
SP3 TFRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19437620 17125792
SP3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16781829 10625617
STAT3 VEGFB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16899623 21731766
TGFBR2 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBLB PIK3R1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
SOS2 HRAS â—¼   GTPASE_REACTION ✅ + 0.8 0.8 Signor 21779497
NCK1 NCK2 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CALM2 FGF12 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CALM1 FGF12 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
NEDD4 AKT1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 19953087 23195959 31390487
MDM2 AKT1 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
AKT1 MDM2 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
KIT CBL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25737303 16780420 15315962 8950973
PIK3R1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 16273093 5218056
PTPN12 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 28065597
PTEN WWP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21532586 33470109 25547115
SP3 SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12414801 11517158 10825178 16734381 9329821 23825960 12200149 15247906
PDGFRB PTEN â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
SEC23A SEC23B â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ITCH TRAF6 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
PDGFRA PIK3R1 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
PTEN PTK2 â—¼   DEPHOSPHORYLATION ✅ - 0.81 0.81 Signor 10400703
CRKL PEAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
CCDC8 FLOT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 24711643
FLOT1 CDCA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
NCK1 SOS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 17474147
ATF4 CEBPB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11018027 20102225
CFTR CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CAV3 CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CFTR CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
EGFR CKAP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25754235 15657067
CNBP MAK16 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
EGFR PTPRG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25970784 31980649
FGF9 FGF20 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FGF8 SRPK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FHL3 PKP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32296183
MAK16 MDM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PDGFB MDM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PIK3CG PIK3R5 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CALM3 FGF13 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
NCK1 SOS1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
GRB2 PDGFRB â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MAK16 WDR74 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
SHC3 GRB2 â—¼   RELOCALIZATION ✅ + 0.82 0.82 Signor 16829981
SOS1 KRAS â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 25624485
BCAR1 NCK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22974441 12135674
NCK2 CBL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24287595
CBL ITCH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12226085 19341794
KIT CBLB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12177062 15315962
CBLB PLCG2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 12093870
DTNA SNTB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 12206805 16713569 24981860
EGFR EPHA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15657067 24797263
GRB2 PEAK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 21706016
NCK2 PEAK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PGF VEGFA â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
VAPB SNX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VAPB SNX6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CALM3 EGFR â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
SP1 STAT3 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SRC TNK2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
CBLB NCK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25218436 16189514 16503409
CEBPB SP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12665574 12847250 16651265
SNX2 EGFR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24797263 9819414
RASA1 GRB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12441060 16189514 16713569
NCK2 SOS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10026169 16713569
STAT1 SRC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14978237 10358079 9344858 16189514
EGFR PLCG1 â—¼   PHOSPHORYLATION ✅ + 0.84 0.84 Signor 1689310
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
FLT4 NCK2 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
EGFR SHC4 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
MDM2 ATF4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27264869 21988832
CBLC ITCH â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12226085
CRK NCK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9837978 8879209
PLCG1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 9020117 6805619
SHC2 EGFR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8610109 16273093 22973453 24430869
SRC GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12624098 9016807 16713569 16189514 11964172
RASA1 KIT â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24728074 11071635
PLCG1 PDGFRB â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6730306 1396585
SRC PLCG1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8657103 7510703 7682059 1689310 16713569 8885868
PLCG1 RASA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9743338 9020117 8977179
STAT3 STAT1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6730629 8662591
VEGFB VEGFA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25241761 26186194 28514442 8702615
AKT1 PTEN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CBL EPHA2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
AKT1 FOXO1 â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 21798082
AKT1 FOXO1 â—¼   RELOCALIZATION ✅ - 0.85 0.85 Signor 18423396
NEDD4 SMURF2 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
PPARG CAV1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12813462 21690289
VAPA CKAP4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
PIK3R1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220480 7642581
TRAF6 SRC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22447928 10635328 16189514 29545793
STAM USP8 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
AKT1 APPL1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
BCAR1 GRB2 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
PIK3R2 TGFBR2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
AKT1 CDC37 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
PTK2 PTPN11 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
CRK SOS2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 19380743 17474147
CRK CBLB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25814554 19380743
CBLB NCK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26871637 26186194 21516116 16713569 25416956 16189514
CRK PEAK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 19380743 31980649 20534451
NEDD4 EGFR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR STAM2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10993906 11687594 15212941 17403676
EGFR STAT3 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 22693070
GNAI1 GNAI3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SRC KIT â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24728074 12444928 12878163
HRAS PIK3CA â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CALM1 EGFR â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CRK PDGFRA â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EGFR USP8 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PIK3R2 PIK3R3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 YY1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
VAPA VAPB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CRK SRC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PIK3R1 PTK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EGFR STAT1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PIK3R1 PIK3R2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CRKL PIK3R1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR TNK2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PTEN PTK2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PTEN SLC9A3R1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMURF1 SMURF2 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
PDGFRB PLCG1 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 7535778
CBLB CRKL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25814554 10022120
CRKL KIT â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11071635 9092574
CDC37 AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31980649 24869908 22504172 12176997
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CEBPB CEBPG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20102225 12177065
ERBB3 RNF41 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
JAK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8536716 11527382
SRC RASA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11389730 16189514 16713569 1717825
CRKL EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BCAR1 PTPN12 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
GRB2 PTK2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
KIT PLCG1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CBL NCK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CBL PLCG1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CRK PIK3R1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EGFR NCK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
STAT1 STAT3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EGFR NCK2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ERBB3 PIK3R2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PDGFRB RASA1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EGFR PIK3R2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
BCAR1 CRKL â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PDGFRB SRC â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CBL PIK3R2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GRB2 KIT â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
JAK1 STAT3 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RNF41 USP8 â—¼   UBIQUITINATION ✅ - 0.88 0.88 Signor 23750007
USP8 RNF41 â—¼   DEUBIQUITINATION ✅ + 0.88 0.88 Signor 23750007
AKT1 FOXO1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
KIT PIK3R1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
PDGFA PDGFRA â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
GRB7 KIT â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24728074 12444928 10377264
EGFR CRKL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18271526 24658140 31980649 16729043 23397142 25754235 25402006
SOS2 PLCG1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10940929 17474147
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
SRC CAV1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8632005 8910575 8621645 29720121
CBLC CRK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10362357 16713569 25814554 16189514 10571044
EGFR CDC37 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25036637 31980649 23956138 24189400 12471035
VAPA EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25754235 31980649 23956138 20029029
SHC3 EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9507002 22973453 9685397 8610109 16273093 8662772
STAM2 JAK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10993906 16713569 10899310
KIT STAT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25241761 9355737
NCK2 NCK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194 31980649
PIK3R1 SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PTPN11 SOS1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
EGFR PIK3R1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ITGB3 PTK2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
NCK1 PDGFRB â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
EGFR RASA1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
BCAR1 PTK2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
AKT1 MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
GRB2 TNK2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PDGFRB PTPN11 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
SEC24B SEC31A â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
ATF4 FGF19 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23205607
PDGFB GRB7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8940081 10508235 9739761
PDGFRA GRB7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8940081 10508235 9739761
PDGFA GRB7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8940081 10508235 9739761
GRB7 ERBB3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 24189400 9516479 16273093 16189514
TGFBR2 SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15496141 11163210 11278251
PPARG FGF21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18467542 19906798 17954559
CALM3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
PDGFRB CRKL â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 9546424 9739761
PDGFA CRKL â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 9546424 9739761
PDGFB CRKL â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 9546424 9739761
CALM2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
CAV1 FLOT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22936677 10212252 25204797 34079125
EGFR SOS2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SOS2 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 18271526 31959764 24797263 24658140 31980649 10675333 23956138 25402006
TNK2 AKT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10652228 11394904 18470881
POU5F1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284 20683952
CALM1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
TRAF6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34938598 19713527
ATF4 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16026328
EGFR BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17145710 17570479 15951569
EGFR CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19446582 15657067 24658140 31980649 22411794 34079125 16407214 12354760 25402006 10781609 9374534 12388423 16799092 15273741
CAV1 PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10066366 11168929 23331499
SRC CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22203672 29899407 17141222 18996392 12941616 15135048 18273061 10829062 31120930 19861161 7782294 16713569 8635998 11994282 17094785 16636290
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
NCK1 CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 7517397 10829062 10372803 10204582 11494134 24287595 10967110 16503409 9851874
CBL PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 17635922 10514377
CBLB PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11087752 17635922 10514377
CBLB NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16503409 16189514
CDC37 SRC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 32707033 31980649 11085988
HRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
NRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
KRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
CEBPG INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2404278 9668047 8817653
YY1 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9199306 7494244 12296377
PTEN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21385900
TNK2 CRK â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 604342200 7033822 17038317
EGFR CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10595738 9480911 9642287 24658140 31980649 11956190 16729043 22973453 8875975 25402006 9617486 16273093 12198159
ITGB3 CRK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
PDGFB CRK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 9546424 9739761
PDGFA CRK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 9546424 9739761
EGF PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8940074 1672440 10473558
EGF PTPN12 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 21376233 7542744 7541030
EGF PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17496910 1334406 19531499
EGF STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28542650 19168569 22162832
EGF PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23613900 17081983 16525023
ERBB3 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23436906 10527633 27756321 21278786 18803307 17148612 22439932 25315821 10572067 24189400 23866081
PLCG2 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 22973453 25241761 25402006 16273093
TGFA EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12297049 24658140 31980649 8663070 10775655 25402006 28988771
NCK1 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 9362449 16273093 25402006 1333047 10026169 8662998
NCK2 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 22973453 9843575 16713569 25402006 1333047 10026169 9737977
STAT3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18367518 21590492 23504318
YY1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22580610 18391986
EGFR PTPN12 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 21376233 7542744 7541030
EGFR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8524316 15284024
SOX10 ERBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11156606 11799060 21672228
ERBB3 PTPN12 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 21376233 7542744 7541030
RNF41 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17384230 12411582 27353365
GNB1 GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15782186 16189514 26186194
KIT GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17452978 10022833 17904548 12444928 7523381 10377264 24728074 16713569 8950973 7523859 8647802
PDGFRA GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
ITGB3 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12005431 9566877 7997267
PIK3CD GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PDGFB GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PDGFA GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PIK3CB GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
ULBP2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11239445 11491531 11777960
JAK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8536716 11527382
SHC3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16729043 12242309 16829981
RASA1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12441060 16713569
HGF PTPN11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17881575 10871282 11323411
SP3 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9223667
HGS ZFYVE9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 11094085
HRAS SPHK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12391145 10802064 12776187
PPARG IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18394717 20064783 20685873
ITGB3 VEGFA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12820653 19267251 17030947
PTPN12 KIT â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 12614164 0265574 8312067
KIT SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8950973 16129412 10377264
KIT PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17496910 7520444
KRAS SPHK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12391145 10802064 12776187
SP3 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19197985 19011236 19994725
SRC KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30644389 26854235 9096340
SOS1 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25624485 23331499 16293107
PDGFA NCK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 7692233 9739761
PDGFRA NCK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 7692233 9739761
PDGFB NCK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 7692233 9739761
NCK1 RASA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16189514 10508618 21664272 9233798
NCK2 PDGFB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 7692233 9739761
NCK2 PDGFA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 7692233 9739761
NCK2 PDGFRA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 7692233 9739761
NEDD4 PTEN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TGFBR2 NEDD4L â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15496141 11163210 11278251
NRAS SPHK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12391145 10802064 12776187
PAX3 SOX10 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10942418 11029584 12668617
PIK3R2 PDGFA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PDGFA PIK3R1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PDGFA SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PDGFA PIK3CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PDGFA PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PIK3R2 PDGFB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PDGFB SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PDGFB PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PDGFB RASA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1375321 1314164 9739761
PDGFB PIK3CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PDGFB PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1396585 8443409 9739761
PIK3R2 PDGFRA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PDGFRA SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PDGFRA PIK3CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PTPN11 PDGFRB â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8119896 6730513
PDGFRB PIK3CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PDGFRB PTPN12 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 12614164 0265574 8312067
PDGFRB SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PDGFRB PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PDGFRB PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17496910 16189514 11172806
PIK3CA SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
PTPN11 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10386953 7522233
PTK2 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11119718 10592173 7537275
PIK3CB SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
PIK3R2 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22402981 8596638 11733063
PIK3R1 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8596638 14665640 11733063
SP1 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16814105 19464346 17376651
PIK3R2 SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
SRC PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 22402981
PTK2 PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 22402981
PIK3R3 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 22402981
SRC PLCG1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
RASA1 SPHK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12391145 10802064 12776187
TGFBR2 SMURF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15496141 11163210 11278251
SP1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10625617 19112177
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
SRC VEGFA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
CFTR SLC9A3R1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
DNM2 GRB2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
SOS1 HRAS â—¼   GTPASE_REACTION ✅ + 0.9 0.9 Signor 23132018
EGFR SOS1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
EGFR PLCG2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
GRB2 SOS1 â—¼   RELOCALIZATION ✅ + 0.9 0.9 Signor 23452850
BCAR1 SRC â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
GRB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
ERBB3 PIK3R1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
PIK3R1 PTPN11 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
EGFR PLCG1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
EGFR SHC3 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
PIK3R1 ERBB3 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 16273093 5218056
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
BCAR1 CRK â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
PDGFRB PIK3R1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CALM3 FGF12 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ATF4 CEBPG â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
PTK2 SRC â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
SEC23B SEC24B â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
SEC23B SEC31A â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EGFR STAT3 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
FLT4 VEGFC â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
PIK3CB PIK3R3 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
SEC23B SEC24A â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
NAT10 UTP18 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
PIK3CB PIK3R2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PIK3R1 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5217342 15556646
SLC9A3R1 CFTR â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6548022 9671706
SOS1 HRAS â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 17084389 5219305
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PIK3CA PIK3R3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HRAS PIK3CG â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
PIK3CB PIK3R1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ERBB3 GRB2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
PIK3R1 PDGFRB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7536927 6730373
CBLC SRC â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CBLB EGFR â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CBLB GRB2 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
SOS1 EGFR â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19531499 18271526 31959764 24797263 7510700 20473329 19289468 10675333 23956138 25754235 8621459 16713569 26005835 9447973
PLCG1 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21706016 7629168 10940929 16038803 9020117 16713569 9281317 7516467
SOS1 PLCG1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10913276 10940929 9020117 16713569 17474147
SNX6 SNX2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 32296183 26344197 11279102 22939629 21988832 22863883
SEC23A SEC31A â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
SEC23A SEC24B â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SNX2 SNX6 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
SRC BCAR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10085298 21034468 10487518 11514617 10542110 15020686 16849545 12397603 12615911 17038317 10739664 12972425 17129785
PLCG1 CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9234717 12941616 25241761 16467851 12061819 9712732 16713569 16503409 17372230 12803489
SOS1 CRK â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8810325 33961781 8943292 31980649 25241761 32203420 19380743 17474147
EGFR EGF â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 25453753 30083275 21822280 12620237 19531499 25080504 12093292 22729867 23597562 18427122 26280537 18271526 10970856 15620700 11684674 21439278 8663535 28988771 2790960 10788520 10085134 16274239 25241761 17697999 9135143 12297050
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
PLCG1 KIT â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14647465 25241761 24728074 16713569 7537096 11071635 7536744
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
HGS STAM2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
GRB2 SOS2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
EGFR TGFA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
EGFR ERBB3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RNF41 USP8 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GNAS GNB1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HRAS RASA1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
PDGFRB PLCG1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
EGFR ERRFI1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
CBLC EGFR â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EGF EGFR â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
PIK3CD PIK3R1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
PIK3CA PIK3R2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
HRAS SOS1 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
SOS2 GRB2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 7629138 14679214 21706016 31980649 10940929 32062451 32203420 20936779 21988832 28514442 19380743 17474147
GNAI3 GNB1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SEC23A SEC24A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CBL CRKL â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL CRK â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
HGS STAM â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL PIK3R1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNAI1 GNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GRB2 SOS1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
VEGFD FLT4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12881528 11532940 9435229 8617204 8700872
VEGFD FLT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11279005 16336962 16633338 11532940 21148085 9435229
FGF19 PIK3R1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
FGF19 GRB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
FGF19 SOS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
ERBB3 GRB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 24189400 16273093 9516479 16189514
PTK2 GRB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10446223 12021278 16189514 25814554 17318180 19473962
KIT GRB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24728074 10377264
EGFR CALM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 19901323 20029029 16497976 15592455 25402006 17389395 18578522 16799092 20068231 7925415 3415247 8639568 18669648 12153558 24658140 17287340 2843348 14960328 18707149 17016520
CRK CRKL â—¼   PHYSICAL_INTERACTION 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
HGF CRKL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10871282 12138161 11146548 10753869 10618718
GRB2 CRKL â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
VEGFA CRKL â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
CRKL BCAR1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL CBL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL FLT4 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
CRKL RAPGEF1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL VEGFB â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
GRB2 CRKL â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRK CRKL â—¼   SHARES_COMPLEX 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
VEGFA CRKL â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
CRKL VEGFB â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
CRKL BCAR1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL RAPGEF1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL CBL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL FLT4 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
CRK CRKL â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRKL CBL â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL RAPGEF1 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL FLT4 â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
CRKL PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRKL BCAR1 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
BCAR1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8978305 9498705 18835194 10592173 8810278 10753828 12345678 8943292 23770091
EGFR CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 31980649 23397142 18271526 24658140 25402006 16729043
CRKL PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9092574 16135792 11418612 23397142 9461587 16982329
CRKL RAPGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 8943292 10753869 8978305 16443220 11466412 8621483 9129019 10907644 18835194 10592173 9374471 10926930 9311917 10339478 11167825 12671687 9344843 9820532
CRKL PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9092574 9461587 11553620
CRKL BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8978305 9498705 18835194 10592173 8810278 10753828 12345678 8943292 23770091
EGFR CALM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 19901323 20029029 16497976 15592455 25402006 17389395 18578522 16799092 20068231 7925415 3415247 8639568 18669648 12153558 24658140 17287340 2843348 14960328 15212693 18707149 17016520
GRB2 SOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 21988832 20936779 19531499 14764585 10940929 19380743 21706016 10359574 14679214 17474147 21779497 9199344 7629138
EGFR SOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23956138 19531499 18271526 24658140 10675333 25402006 24797263
SOS2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17496910 12628188 17673906 21779497
ERBB3 ERBIN â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 23220880 30854046 28274957 18039657 16843263 26545934 22046346 23843458 30314968 23948973
AKT1 MDM2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
AKT1 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
PTEN AKT1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218262 17409395 19440036 19847259 19945467 20609352 21084277 22179046 22465479 23732914 24030100 24254977 25364523 26597054 27328425 27572739
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
PIK3R1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10527852 16799564 19442713
TNK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22322295 11394904 25678401 20333297 10652228
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
INS AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 29432553 23912456 11679435 23866690 17335965 24646332 23798298
AKT1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18578522 10896934
AKT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 21440011 10358014 11756412 10358076 31308176 20452955 21798082 11410590 20398329 11311120 11544290 28279977 10217147 15132996 23331499 19216069 11237865 20214616 11463845 16076959 11030146 12228231 9829964 18951090 23180781 17570479 10102273 18593906 17646672 16680151 12456685 18423396 18985696 18988627 17962350 30728292 16670091 18786403 14664696 25241761 16341064 11980723 10358075 2984676 13679577 12560069 10377430 11251083 17680028 2987962 17254970 11864996 20041807
AKT1 APPL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 10490823 25814554 12621049
AKT1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19903340 15987703 10790335 20596030 10592173 20605778 10866658 12077256 11035045 16107342 12297295
AKT1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11175347 11756412 12356771 15733869 20452955 20398329 11160957 10217147 19216069 20214616 11463845 9829964 7958915 12235136 16680151 17646672 9687510 8887554 11698596 8688081 17680028 9528766 11018520 11969286 12519783 11909979 15725726
AKT1 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23041284 24497960
AKT1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 11756412 11923280 20856200 20452955 20398329 18332867 19664995 10217147 11154281 19216069 20214616 11463845 19166854 15527798 9829964 17570479 16680151 17646672 12145204 15169778 15140942 25241761 11715018 25209720 17680028 21930127 11504915 29311840 15574337 23397142
DNM2 AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1M1 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
ATF4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18829529 20824063 14747470 15788408 20221394 24347168 23908598 18172307 18617696 23649506 22915762 18451308
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
CRK BCAR1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 11146654 11353765 12094222 12432077 14697347 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 9808620
BCAR1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
BCAR1 RAPGEF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK BCAR1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 11146654 11353765 12094222 12432077 14697347 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 9808620
BCAR1 CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
BCAR1 RAPGEF1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
PTK2 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 8649427 7479864 12135674 15673687 8810278 9038154 8670206 9285683 11604500 11119718 12480533 24939893 8621540 11577104 9360968 9148935 10592173 12119061 12972425 9360983 10092764 21855630 10753828 11839772 18233957 10545505 12615911 8662921 11514617
PTPN12 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9920935 8887669 11432829 12714323 9748319 9285683
SRC BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 19901323 24962474 11514617 8670206 15316024 20927395 8070403 17389395 12480533 22710723 30422386 25976166 17570479 21963850 12972425 20103658 17129785 10487518 15817476 21301050 10739664 17038317 21765460 17016520 12397603 15212693 15020686 10542110 23457577 10085298 12615911 15272013 21034468 11604500
BCAR1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 9920935 11369773 11278916 15673687 8662907 9581808 8631823 8070403 10747099 12065577 10329689 16267043 10592173 10208419 17038317 18835194 20627867 16413489 10753828 8943292 9860979 11839772 14657239 12799422 19380743 15492270 10085298 12615911
KRAS CALM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 27410739 12727204 28666118 16043511
EGFR CALM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17145710 19901323 20029029 12359306 16497976 25402006 17389395 18578522 16799092 20068231 3415247 7925415 18669648 12153558 24658140 17287340 14960328 18707149 17016520
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
CAV1 TGFBR2 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
CAV1 PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 18988627 16189514 10066366
STAM2 CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
HGS CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
PIK3CD CBL â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9590251 7537740 8995358 9259313
EGF CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
CRK CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CBL RAPGEF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CBL STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
CBL CDC37 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
CRK CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CBL RAPGEF1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
CRK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 8683103 16289966 8626543 8621483 9617486 16713569 9416834 8524328 10962563 8626404 9367879 8662998 12393469 11792427 15581361 9013636 15581362 9178909 9988765 18835194 8943292 20697350 9129019 19380743 25814554 9461587
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 9234717 10347229 18988627 17635922 10514377
CBL PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 9092574 19190244 11406619 11133830 7629144 17635922 11526404 8662998 8995358 8080844 15107835 23109003 17722974 8621719 16107703 9414268 10514377 15790353 19531499 22315502 19380743 25814554 9461587
CBL PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7517397 9712732 12941616 25241761 12061819 23109003 9234717 16503409 11709089 16713569 17372230 16467851 12803489
CBL PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8641358 9119889 19380743 8621719 7629144 17635922 10514377
CBL KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9092574 17904548 25737303 8950973 15315962 17635922 10514377
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 98.0 1.0 Omnipath 9092574 19190244 16289966 11406619 7642581 11133830 10358153 8941725 9234717 8612729 11157475 10620516 16713569 21203488 11418612 24113870 17635922 18374639 14530346 11526404 8662998 8995358 11030146 9890970 9541596 11042121 15581361 9890943 8080844 7791764 9178909 15107835 8995243 8695807 9988765 23109003 11944898 15556646 17237826 10025673 17722974 8621719 16135792 16107703 16219545 9461587 9160881 9414268 16982329 19861161 10514377 9918857 11087752 9092538 11994282 9259313 15790353 19531499 9174058 8702998 25814554 22315502 19380743 10918571 8896416
CBLB KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15315962 12177062 17635922 10514377
CBLB CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 8626404 19380743 12697763 25814554
CBLB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 19531499 11375397 10086340 12577067 10542134 17635922 10514377
CBLB PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11087752 21780115 10488096 19531499 11526404 15032589 23109003 22880054 17635922 10514377
CBLB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 10022120 25416956 21706016 31467278 32814053 9614102 17635922 11375397 8626404 16189514 21900206 20936779 27107012 12577067 10514377 19531499 10086340 29997244
CBLB PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 11087752 21780115 10488096 19531499 11526404 10086340 15032589 23109003 22880054 9614102 17635922 10514377
SRC CBLC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9988270 20525694 24425877 14661060 22888118
CBLC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10362357 22888118 17635922 10514377
PLCG1 CDC37 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 17177598 16187797 15284455 16953218 17712310
STAT3 CEBPB â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
CEBPB INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9353292 21063109 19164449 10649437
CEBPB KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11500490 18444174 16107878 10318842
CEBPB PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22473998 23934183 7557387 12524424 16431920 22610404 15110775 18694725 17242167 16054042 15158467 9950217 10862621 20829347
CEBPB STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11134330 18266962
CEBPB FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18391971 11893744
SLC9A3R1 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 9671706 12471024 15553237 17110338 10852925 17244609 9677412 28360110 18754678 12403779 11158634 19446522 11304524 9613608
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
VEGFA CRK â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
HGF CRK â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10871282 12138161 11146548 10753869 10618718
CRK RAPGEF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK FLT4 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
CRK VEGFB â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
VEGFA CRK â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
CRK FLT4 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
CRK RAPGEF1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK VEGFB â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
CRK FLT4 â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
CRK PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
PDGFRA CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 19426560 25241761 10733900 16713569 9546424 27686861
PIK3R1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
PDGFRB CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 19426560 10733900 16713569 27686861
CRK PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 7561682 25814554 12370821 20068231 11602246 10085298 12615911 7509446 7529876 17016520 11314030
CRK PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25814554 35044719 19380743
CRK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
CRK RAPGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 8621483 9560161 9122199 17515907 10592173 11870224 9591773 18835194 8943292 7512734 19001122 7806500 20697350 7531694 12054111 19380743 17474147
CRK PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 35044719 19380743 25814554 11418612
DNM2 OCRL â—¼   PHYSICAL_INTERACTION 19.0 1.0 Reactome 15260957 10542231 19575674 24966051 10535736 17765681 19536138 21316588 14622578 17158794 21779028 9428629 11082044 22099461 21445324 21613550 14622579 25107275 24581490
TGFBR2 EGF â—¼   ENZYMATIC_REACTION ✅ 41.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16424049 16474430 16572188 17070508 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
EGF EGFR â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
EGF GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17081983 19531499 17673906 10973965
EGF SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23349873 19481075 15845350 22927910 27462789
EGF EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 131.0 1.0 Omnipath 17145710 17081983 21822280 20813200 23613900 9135143 25453753 21303971 10209155 26821125 12297050 27387652 25241761 30083275 12093292 30197274 21649524 19531499 18762250 16729043 26921391 17697999 17575160 21722395 12620237 19129184 10788520 23331499 3494473 15620700 14568001 15958209 24096486 18253097 16843263 18320059 21532939 10085134 22260327 15708576 26280537 23912460 21858221 11116185 10970856 27462018 18427122 25080504 20953304 19135477 11684674 8639530 27564112 18270696 2790960 17971399 23185569 19895983 28988771 29617357 23597562 19531623 23950932 21071413 8663535 6289330 16274239 17563729 21439278 20458382 22216880 18271526 12771140 21311755 24709886 25366117 12648462 21107857
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
PPARG EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15486348 18332871 18288266 23370527
TGFA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 21722395 28988771 25402006 23155381 3018723 23331499 16585207 10209155 24658140 10775655 31980649 12297049 8663070 12648464 27635238
USP8 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16520378 16120644 25853104 20736164
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
PTEN EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
EGFR PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 31980649 25241761 16273093 24658140 17570479 25402006
EGFR SHC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 24212772 9507002 16273093 11791173 8760305 8662772
EGFR PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17496910 31980649 25241761 16273093 24658140 25402006
EGFR SHC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 11350724 16273093 8760305
EGFR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23956138 12070153 20145033 14967450 20032199 21573184 25402006 10358079 23894143 14966128 24135280 25241761 14963038 24189400 15657067 24658140 15485908 15950906 18258752 31980649 9756944 22693070 12873986 15951569 15284024
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9544989 19531499 9447973 16713569 12577067
EGFR PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16713569 16919435 25402006 10806474 29435030 20473329 7657702 19339212 17496910 15657067 24658140 19625610 7529872 20802513 31980649 10545505 24043698 15951569
EGFR RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 8647858 16273093 7991458 1850098 17570479 1633149 1385407
EGFR NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 1333047 23331499 10026169 9737977 24658140 16713569 25402006 9843575 1333046
EGFR ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 23436906 7929151 21278786 24189400 23866081 17148612 12648464 27756321 18803307 10527633 10572067 22439932
EGFR PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17496910 31980649 23956138 19531499 16273093 24658140 11172806 1334406 25402006
EGFR TNK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 20359967 8647288 20432460 17182860 15951569 8497321
EGFR STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 23956138 12070153 11839738 10918587 11447289 11997436 14967450 25402006 12040186 24797263 15173823 7543024 15322115 10358079 6321473 11294897 7690989 10982844 19568798 12637327 14585353 15199124 17496910 11438544 10748192 24658140 7657660 12817007 31980649 22693070 9355737 19615955 11152457 15284024 15567848 7592750 16488589
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
EGFR PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 89.0 1.0 Omnipath 19901323 17081983 16273093 9207933 2472219 16497976 15592455 16126727 16713569 24797263 17389395 8578591 23331499 7991458 1689310 20068231 17570479 9176240 12803489 16153436 7993895 16038803 7805859 15864276 1708307 7682059 15144186 11983899 12601080 9756944 15212693 14568990 12061819 9020117 8885868 12648464 8657103 15951569 17016520 7693694
EGFR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17496910 26918608 7797556 25241761 19531499 16273093 8662998 14967450 16713569 21701776
EGFR ERRFI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23956138 24797263 19531499 29574142 18046415 24189400 18271526 23273428 18776048 11843178 19815557 20946980 26280531
EGFR NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1333047 23331499 31980649 10026169 16273093 9362449 8662998 24658140 25402006 15951569 9843575
SRC EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24457997 28957431 26788993
EPHA2 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17496910 23331499 7982920
NRAS ERBB3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
KRAS ERBB3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
HRAS ERBB3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
ERBB3 PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16273093 17496910 24189400
ERBB3 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17496910 16273093 24189400 16729043
ERBB3 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 17145710 18803287 16273093 23331499 21278786 21071413 11694521 18988627 10383151 9130710 17496910 11546794 20227043 20007781 24189400 10572067 22439932 9756944 21075308
ERBB3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9756944 24189400 11173924 24658140 14967450 16729043
FGF1 HGF â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 14517404 16272825 16682805 26183471 9242465
STAT3 FGF2 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
FGF2 HGF â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11874475 18232728 18633355 18776941 19508171 19631971 21098712 22652804 23123598 25374926 9242465
STAT1 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16494848 23086340 19556344
SOS1 FGF23 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
GRB2 FGF23 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
PIK3R1 FGF23 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
VEGFA FLT4 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
VEGFB FLT4 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
GRB2 FLT4 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
VEGFA FLT4 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
GRB2 FLT4 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
VEGFB FLT4 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
GRB2 FLT4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
FLT4 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SRC FLT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16076871 12881528 20431062 18083107
VEGFC FLT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16530705 24798152 12881528 16336962 8700872 16633338 11532940 9435229
FLT4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9927207 8662748 7675451 7970715
FOXO1 SMURF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21798082 15125842
FOXO1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16670091 12966085 17317207
GNAI1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 10753828 9722546
PIK3CA GOLGB1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 19345670 9918857 19438505 23168613 27795560 31066629 17764812 11027663
SOS1 GOLGB1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19345670 23168613 27795560 31066629 17764812
PIK3R1 GOLGB1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 19345670 9918857 19438505 23168613 27795560 31066629 17764812 11027663
HGS GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
SOS1 GRB2 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 8810325 33961781 8695800 7510700 8626525 34407391 16520382 10570290 16906159 16893902 7642581 8816480 9447984 12577067 11964172 8112292 8493579 7664271 16713569 7516467 19380743 9009162 10207103 17474147 10477741 32062451 7629138 21706016 20473329 19323566 9872323 32203420 7514169 21988832 28166272 28514442 9716598 11997436 9344843 15192046 10716926 8479541 14679214 8943292 31980649 7629168 7559490 9478994 7527391 8188688 11960376 10025673 11726515 7773779 10319320 9569023 9797459
STAM2 GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 VEGFB â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 VEGFA â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 PLCG1 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 VEGFB â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 PLCG1 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 VEGFA â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
NRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
GRB2 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 VEGFB â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 VEGFA â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 PLCG2 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10072481 10086337 10567412 10781611 10811803 10982827 11169415 11447289 11777939 12175651 12640133 14764585 15567848 15574420 16102570 16329184 16582911 16887996 17496910 17673906 19449109 19494291 19909365 23620508 25137453 26552706 7523143 7890616 8551221 8649391 8976179 9489702 9535722
PTEN GRB2 â—¼   REGULATES ✅ 15.0 1.0 ACSN 10648629 10753747 11747822 12040186 15584861 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523
KIT GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 24728074 8950973 7523381 10022833 7523859 8647802 16713569 17452978 17904548 10377264
PDGFRB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7935391 16713569 7486683
PTEN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
GRB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 145.0 1.0 Omnipath 9544989 9872323 7642581 15746962 11726515 8621483 23334917 16520382 11997436 21706016 10359574 8950973 7664271 16713569 16893902 16906159 21988832 19323566 9009162 10716926 11964172 7629168 9815779 10592173 9716598 8647802 28166272 7773778 7773779 18778683 8188688 10319320 8810325 9344843 23452850 11960376 8816480 10025673 7510700 8940013 12955078 9697839 12345678 10477741 8493579 8943292 12577067 7862167 9199344 8112292 7898932 10207103 8695800 19531499 10570290 7760801 20005866 19380743 9447984 8235613 8479540 7527391 14679214 8479541 17474147 7514169 7629138
GRB2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9281317 15953601 7629168 9020117 16713569 10940929
GRB2 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 10806474 12558988 8649427 8816475 11119718 16298995 7597091 7997267 9148935 12110680 12005431 10085298 16713569 10749687 10354709 21900206
HGS HGF â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM2 HGF â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HGF STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HGF SOS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038378 7513258 9070211 8703035 7708691
STAT3 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14647442 18835816 16407846 11278729 23954444 17967179 12168776
SP1 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9223667 17967179 12482909
PPARG HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22472882 24569592 16291834 11292834
PIK3R2 HRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
HRAS PIK3CB â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
HRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
SP1 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8106522 8208618 3012774 11559711 21931711 8027084 1776841
RASA1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 10769036 11389730 23331499 18829532 7628625 9219684 10592173 8663024 16713569 26721396 8360177 8537347 1904555 10394594 2833817
SOS1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12628188 10208427 16713569 10913276 23331499 18454158 15507210 10592173 17673906 17496910 26721396 20133692 19141281 23132018 11560935 9447984 9690470 17084389
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
HRAS PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9069260 9113989 9235916 21779497 11739523 10545207
HRAS PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9069260 9727023 17145710 10922060 11136978 21779497
HRAS PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9069260 25241761 10212255 11313862 9150145 16713569 15021914
HRAS PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 9069260 9113989 8052307 24412244 17540175 9931431 11313862 14724584 10592173 9150145 8665852 10783161
SP1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8940191 8184747 11026572 14593001 12217897 8910531 7896792
SP1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9348238 17446237 23626778 18664368 14744869 15001547 23027183 14998783 17449871 15330762 19485892
SRC ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10330414 17473008 8631894 18156175 25694433 18840695 18364349 18398066 10592173 16935858 21956114 17353363 18088087 12359711 15212693 14996908 15695822 15699036 11723131 20702409
ITGB3 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9169439 8649427 10545505 7657702 8636223 10022831 19339212 11927607 11940607 19161977 10592173 16919435 7529872 11553709 8755653 7512751
JAK1 STAT1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10426994 11907067 12244150 12811837 15536084 16081783 16713974 16785506 19833085 20856220 21840487 23124025 24751819 7512720 7521688
JAK1 STAT3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10426994 11907067 12244150 12811837 15536084 16081783 16713974 16785506 19833085 20856220 21840487 23124025 24751819 7512720 7521688
JAK1 PTK2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
JAK1 STAM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10899310 10993906 16713569
JAK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 121.0 1.0 Omnipath 18691551 20169197 19901323 12626585 12759422 15805299 10918587 9305919 15261459 21420464 8272872 10851062 12093291 17878297 12626508 12351624 12040185 16497976 15592455 20966397 8662928 18941194 17389395 23331499 11306517 8756628 12576423 11350938 12244150 18669613 7796300 11294897 24710148 11163236 11722592 11418623 8085155 12244095 21690253 14764663 9535918 21098725 9083098 8662591 22905257 14565860 27774606 8626374 19723038 29145629 26260587 9566874 24501689 25297818 9651359 11940572 11429593 11564763 12517932 14551213 8662795 19535621 23124025 18389480 15284024 11706020 11850821 17016520 9582023 17595657
JAK1 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 8790359 21071413 8995399 12270932 12403768 9794795 11036942
JAK1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 132.0 1.0 Omnipath 35317858 11839738 10918587 15261459 34950606 11306517 8756628 12244150 8156998 9535918 10748192 7657660 12817007 23257612 27774606 25297818 22306691 8631301 7510216 14963018 15284024 24243840 7592750 10851062 11823427 23331499 7532278 11418623 11722592 18988627 12637327 27387064 8662591 10022928 19088846 32953130 7796299 7504784 23124025 19787091 24058793 20169197 7543024 15322115 18941194 19534553 15978943 14978237 11294897 14764663 21429244 14565860 34228987 25386349 18989459 34521819 9020188 19535621 10982844 21576360 12759422 18508557 8232552 12093291 12040185 20006573 8662795 7690989 20087684 11438544 20035788 11972023 29145629 9355737 11152457 12517932 18389480
JAK1 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9774657 15021914
JAK1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9774657 15021914 7544789
KIT STAT3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
SP1 KIT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24008320 20833840 9834219
SRC KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12878163 7520444 10523831
KIT PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24728074 22806893 7523381 9528781
KIT PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9092574 17496910 1382595 11071635 25241761 24728074 7509796 7537096 12878163 10022833 16713569 7520444 17452978 9233773
KIT STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11839738 10918587 11447289 11997436 12040186 21135090 15173823 7543024 15322115 6321473 11294897 10358045 7690989 15567848 19568798 12637327 14585353 15199124 17496910 11438544 25241761 10748192 7657660 12817007 9355737 19615955 11152457 10982844 7592750 16488589
KIT PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9092574 17496910 11071635 24728074 10022833 7537096 7509796
PIK3R2 KRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
KRAS PIK3R1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
KRAS PIK3CB â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
KRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9727023 16189514 10542052 21779497
VEGFA NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFB NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFA NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFB NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
NCK1 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
NCK1 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
PDGFRB NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1333047 23331499 10026169 9362449 16189514 16636066
NCK1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 10026169 10206341 7862111 17474147 8810325
PDGFRB NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 10026169 9737977 11027258 16713569 16636066
NCK2 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10592173 11950595 16713569
NEDD4 PTEN â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 17218260 17218261 17996703 18562292 19652529 22679284
NEDD4 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17218261 23331499 21071413 18307411 17218260 18562292 18498243 19345329 19652529 30594392
PIK3R2 NRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
NRAS PIK3CB â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
NRAS PIK3R1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
NRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
SOS1 NRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 7923364 11560935 9690470 21779497 8493579
NRAS PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8052307 7820549 9150145 8665852 21779497
PDGFB PDGFA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9334164 10508235 1311092 8900172
PDGFA SRC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 7685273 9488729 10508235 9739761
SP1 PDGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15297375 9453298 9321833 9351401 22964636 7499234 10364563 11823426
PDGFA PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15207812 25737405 7679113
PDGFA PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 23331499 9739761 25241761 7679113 15767546 21071413 15207811 2544881 11297552 152078112544881 11803579 15207812 28267575
PDGFB SRC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 7685273 9488729 10508235 9739761
PDGFB PDGFRA â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFB PDGFRB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFB PDGFRB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFB PDGFRA â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
SP1 PDGFB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22415074 11222751 15175554 11967988 8662647
PDGFB PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9739761 15767546 152078112544881 23331499 21071413 16189514 18988627 15207812 28267575 7679113 15207811 2544881 11297552 9677323 10806482 11331882 11803579
PDGFB PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9739761 20577048 30150707 16189514 15207812 28267575 7679113 11297552 15207811 20534510 17981115 10806482 285049611903042 11903042 11331882 2850496
PDGFC PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 23331499 9739761 10806482 21071413 11342471 11297552 15207811 18988627 20534510 15207812 28267575
PDGFC PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 11297552 19795151 32196115
PDGFD PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 1520781114514730 23331499 15207811 21098708 14514732 15207812 28267575
PDGFRB PDGFRA â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
SRC PDGFRA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 7685273 9488729 10508235 9739761
PDGFRB PDGFRA â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFRB PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 21071413 2161888 2542288 7523122 1847074 16189514 11331882 10417313
PDGFRA PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24043698 20802513 29435030
PDGFRA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9988270 17081983 14661060 6273838 15489898 11278940 15845350 12753909 11804588 7578094
PDGFRA PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 12601080 17081983 16038803 25241761 1689310 1708307 7682059 15144186 8885868 16126727 15592455 7535778 8657103 16153436
PDGFRA STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17496910 11447289 19615955 9484840 16488589 6321473 11997436 12040186 19568798 15567848 15173823 14585353 15199124
PDGFRA PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17496910 25241761 8702949 17452978
PDGFRB PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 8622870 19690332 8041791 18083107 8538796 23331499 19534553 11684012 7530043 16189514 12721296 12522270 8959326 17287340 16094384 7688466 8226787 8119896 12531430 11266449 12681492 12614164 8183548 23397142 7691811
PDGFRB PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 10752619 8564419 1372092 7486683 7692233 7536927 16713569 11710529 8382612 8086421 11896612 8670861 8388538 9153411 1330535 17496910 1314164 16135792 7680644 19864249 10697503 15377662
PDGFRB PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17081983 7486683 2472219 16126727 15592455 7535778 16713569 23331499 1689310 11896612 15641795 16153436 16038803 23063561 1708307 7682059 15144186 12601080 1396585 8885868 8657103 8443409 23397142 15212693
PDGFRB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15489898 18315570 16189514 9010229 2173144
PDGFRB STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17496910 8549654 11447289 19615955 9484840 16488589 6321473 11997436 12040186 19568798 15567848 15173823 14585353 15199124
PDGFRB RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11896619 1375321 23331499 8382774 1314164 7486683 1850098 10697503 16713569
PDGFRB PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10806474 20802513 16713569
PGF VEGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12796773 25241761 12086892 8621715
SRC PIK3CA â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 12682286 15314172 20861220 18657504 11689445 12431978 25587652 11044445 22266855 11029403 11029009
PTEN PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
PIK3R3 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8596638 22402981 9415396 11733063 26496610 25814554
SRC PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12750372 10592173 17275257 10830300
PIK3R3 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8596638 22402981 11733063 25814554
PIK3R1 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8596638 25241761 20713702 27107012 11733063 21825134 32814053 26496610 8139559 14729945 10358930 14665640
PIK3R1 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9113989 8596638 21827948 12147247 11733063 22020336 24165795 31031754 14665640
PTEN PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
VEGFA PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFB PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
STAT3 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733515 24218138 23963458 15793565 16293640
PTPN11 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 11593409 18950707 15790353 23109003 16371368 17722974 22315502 16107703 9660791 9918857 8080844 9632795 10973965
TGFBR2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9435577 19114990
PTEN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
PTK2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10806474 8649427 7537275 10973983 12554777 16713569 9416004 19889638
PIK3R1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17474147 19531499 25241761
PIK3R1 PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17474147 25241761
SRC PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21780115 15032589 11526404 23109003 22880054 10488096
TGFBR2 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9435577
PTPN11 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18950707 23109003 16371368 17722974 22315502 16107703 9660791 8080844 9632795 15790353
PLCG1 SRC â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483
PLCG1 SRC â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483
VEGFB PLCG1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFA PLCG1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SRC PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 8388373 16497976 16126727 16713569 17389395 1689310 20068231 17570479 16153436 16038803 1708307 7682059 7510703 18594017 12601080 8885868 8657103 17016520
PTK2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8660853 26278977 10430888 23397142
PLCG1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15953601 12084069 7629168 9020117 16713569 10913276 17474147 10940929
PLCG2 SOS1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11390650 20484116 10811803 12471105
SRC PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 30819914 12181444 11606584 14656219 7682059 15144186 11507089
STAT3 POU5F1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19151334 20505821 15277698 18212089 17068183
PPARG PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18065496 16775433 16425225 23867870 20198337 11378386
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
SRC PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 30323259 10322133 26385316
SLC9A3R1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23118026 16456542 21990315 24012959
SRC PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24830552 22891331 12869565 21532586
PTEN PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9616126 15717329 10427092 23109003 10400703 10592173 9927060 23397142 11857088
PTEN SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
SRC PTK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11476890 12531888 16919435 17496910 17517963 20027185 25572304 26552706 27216177 8892616
SRC PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 216.0 1.0 Omnipath 27351421 23242524 16254240 12370821 21940449 26142360 17525734 10593973 14604860 17389395 19171305 22402981 19339212 22353809 9748249 8941336 17570479 12464388 25226367 15611085 15817476 25241761 26393679 27978555 26833789 11927607 17828307 25913180 26866924 15247219 10085298 12387730 19055942 9507031 21454698 10973994 32814053 21057587 27931517 27438371 18793427 19695571 15735019 18560762 10592173 25319025 24389213 21852560 26689988 14984767 7505391 19568240 20103658 20822514 25868388 23275294 28423510 23764511 19625610 15561106 17192257 19138410 19369195 17088251 12753909 28701735 29190494 17016520 15598735 18814847 11821402 11418135 15728464 16291744 25067788 11602246 16713569 22287273 9032297 7997267 12960434 11369622 20616959 26079101 19534553 10931187 22710722 20068231 25866790 21347260 9822703 28202937 16153436 11980671 21855630 19826415 18464795 7529876 20621036 9330873 21473875 9425168 28956212 12615911 15951569 25814554 12876384 17438336 15212693 16966330 20705914 20847951 23729178 20407018 12558988 25127991 25918719 12590707 16360410 8054685 18814027 11696015 22800863 17117420 12495636 11278488 9864370 21776383 18083107 22814579 22194915 20515733 11119718 9148935 10428489 15743500 20655298 23065768 28213315 26923073 24015220 17289681 12110680 22006118 24164353 23109003 18935208 10753828 18233957 8816475 25118939 19664994 25530216 16760434 9330875 21266176 21034468
PTPN12 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19595712 10400703 9497381 21876001 11432829 11314030
PTPN11 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23335101 7589239 10082579 21726809 14572662 15561106 8986614 16189514 10655584 19698715 16920701 15598735
PTK2 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20576130 25241761 11278462 16189514
PTPN11 STAT1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10358138 11447289 11572860 12138178 12270932 12707331 15240681 15699106 15713798 19833085 9751747
PTPN11 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10409724 23331499 18508557 12040451 16189514 11594781
PTPN11 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18757826 18482983 10698938 17974954 14687660 24632723 20308328
PTPN11 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12577067 9632781 9344843
PTPN11 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 18508557 12270932 18832710 18988627
PTPN12 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19595712 18482983
SRC RAPGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 14551197 10318861 15320955 17474147 15212693 12734187
SRC RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11389730 1717825 16713569
USP8 RNF41 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15314180 23750007 17035239
SMURF1 TGFBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11278251 15221015 22298955 15761148 21572392 27048878 22949611
SRC SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17474147 9856337
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 19671799 12509426 12560084 16638750 15342781 10910082 19147754 22992725 15217947 15737464 11904305 12429844 15688401 15544046 12615726 11678207 15188178 18021292 15883203 15477724 18454179 23652833 16239639 23369005 8910439 15026340 11007955 12644537 14597566 18575762 11232768 11731421 12482909 12570801 15582599 16540671 16790435 18632621 9264407 10581162 16788159 11040101 21115498 23765166 11060301 22326662 23506169 15613498 15970595 11191053 10816575 12975317 20435036 16949073 11980848 14647449 15302997 9271438 15039660 16982770 11559575
SP1 TGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15533438 1501890 7936640 10828826
SP1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18053089 11507078 22028617 15647279 11687969 10982796 12750289 15895377 10766860 9632722 15905358
SP3 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12644537 14597566 12509426 9264407 10816575 20435036 14744778 14662796 15477724 14647449
SRC STAT3 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 16472776 17192274 19930715 22131018 22677902 23589069 23691193 24030100 24403062 25687758 27036022 27452906 29556339
SRC STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 11839738 10918587 9344858 7543024 15322115 10358079 14978237 11294897 7690989 16189514 12637327 11438544 10748192 7657660 12817007 9355737 11152457 10982844 7592750
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
SRC WWOX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 32185845 26120275 31752354 25441426 19366691 16115915 16288044 18371080 27551439 27845895 25650666 31315632 12514174 15070730 15664696
USP8 STAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16520378 10982817 20736164
STAT1 STAT3 â—¼   DOWN_REGULATES ✅ - 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19122651 17558387 22693070
STAT3 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 25609649 8662591 12070153 31462771 25241761 11722592 8710878 9794795 23268184 15284024 16189514 9535918 11594781
STAT3 VEGFA â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 22076197 19880237 12824281 20232316 18320073 20482858 17557905 21354136 19020709 17937859 20880395 25101566 16007214 19284568 19336759 20236940 10744750 11960372 15688401 19082717 21344490 20939432 17533737 21733558 18021292 20720018 11744720 23104276 16540670 11960378 20043094 21278793 21418908 15665043 15735682 21172343 23756865 20052595 17169602 18184402 21731766 23911788 12545153 22313388 16899623 20709526 18408167
STAT3 VEGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17987801 16716598 13130303 7768934 11528470 9278421
TGFBR2 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFBR2 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 12717440 19050695 11133108 14557817 19920116 22710166 19114990 12767520 22703233 23331499 11013220 20060931 17934056 21614932 17673906 20644162 24132110 18922473 9865696 22943793 20519943 21900405 12154066 7594497 18758450 15548370 24336330 21278795 12724770 19010789 15265520 16474430 26192618 12809600 19109155
TGFBR2 ZFYVE9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9865696
VEGFA VEGFB â—¼   PHYSICAL_INTERACTION 58.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319