Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SP3 TAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15706661 15869407
GSK3B AXIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
STAT6 ARG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17312100
RORA G6PC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19887649 21818335
SP1 ABCC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22086197 10373428
PDX1 ABCC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7937976 20418895
ABL1 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 DAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
PPARG APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16542871
SMARCC1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603 18581278
AR POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18703637 15375188
AR SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20739403 20610535
AR CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24810056 20610535
AR PTHLH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 8462465
AR SMARCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603 20610535
AR NCOR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19351840 20610535
AR CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16492776 16344550
AR MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14619959 20610535
AR NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887629 20610535
AR RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12069693 20610535
AR TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21303954 20610535
AR SIN3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 16254079
AR RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24119295 20610535
HNRNPK AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18413735
ATF1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10075672
SMAD4 ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10480932 23331499
NR3C1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17016446
ATF2 TNFRSF11A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10327051 8382609
ATF2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11243868 19948881
ATF2 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20102225 23661758
ATF3 ATF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23850759 26587781
ATF3 ATF4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 23850759 26587781
KLF4 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21205742
CEBPB ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16989641
NFKB1 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24100018
ATF3 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20565867 21467165
DDIT3 ATF3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TTR ATF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ATF4 XIAP â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 23850759 26587781
ATF4 F7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22848420
ATF4 TNFRSF11A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24005670 20628199
DAPK1 ATF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ATF6 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21821716 18450959
ATF6 SRF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9271374
ATF6 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9837962
ATF6 S1PR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21355074 17307147
SP3 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10811658 24219545
STAT3 BATF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21296860 12444555
SP3 BPI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14623259
SPI1 BPI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14623259
CAMK2A SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEBPB CARM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20111005 7894901
CARM1 DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CARM1 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6803829 19101556
CARM1 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24434208
TP63 CASP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23703390 16103071
MAPK3 CASP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219611 17290218
CASP8 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11002417
CASP8 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17581882
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOXO1 CCL20 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25918228 22240809
FOXO1 CCNB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17609436
CDK2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9199329
RARA CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18829110 23062266
FOXO1 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17873901
CEBPA MYC â—¼   DOWN_REGULATES ✅ - 2.0 0.8 ACSN 11340171 20581311
SP1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10373535 12049196
CEBPA ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22568493
CEBPA VLDLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10064725
CEBPA MSR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9743233
CEBPA FABP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15110775 15158467
CEBPA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24429361
CEBPA ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
CEBPB KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23456364 17301242
CEBPB LBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9442384
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
CEBPD MSTN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20844262 24011072
CEBPG IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7692852 8817653
CEBPG PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10862621 12524424
CEBPG HAMP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21289291 12183449
CEBPG PRTN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10677505 11290610
CEBPG YWHAE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17303761 23266643
CEBPG PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9774647 8626491
RELA CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
TFAP2A CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10652362
NFKB1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
FOXA1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24440874
NR3C1 CPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9774647 10562461
CREB1 SFTPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12161428 11368910
CREB1 SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14742439 20739549
CREB1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10909971 22554507
CREB1 CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11874984
MAPK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
SMAD4 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9689110
MAPK11 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11532940 11335727
MAPK3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
CREB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16862174
CREB1 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
CREB1 SMARCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
CREB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
RORA CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24226095 14687547
SP3 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12200429 20096088
STAT6 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15145939 10373589
NCOR2 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12589049 10612426
MAPK1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8941362
SMAD4 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9679056 9679060
CREBBP FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10973497
CREBBP SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9679056 9679060
PPARG CYP1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18308446 15521013
KLF9 CYP1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1356762 12036432
NR3C1 CYP1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9512490 2916850
STAT3 DAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24217921 23438478
FOXO1 DAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12351634
SMAD3 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11740493
SMAD4 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11740493
DAXX NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17081986 12595526
FOSL2 DDIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DDIT3 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19029092 19164449
KLF4 DSPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23430263 23558921
MYC EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18365874 11509655
EGF MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17081983 16024629
STAT3 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731598 14966128
SP3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20435036 20407012
RARA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11788593
EGFR PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499
SPI1 ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9689920
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
ESR1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19797124 20819530
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
ESR1 SLC22A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22212555 18414489
ESR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16144913
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
MAT1A ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11146623
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16144913
PPARG FABP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20592862
MECOM FOSL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1119229109 22308434
TFAP2A FOXA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24835590 22577344
FOXA1 NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8495744
NR3C1 FOXO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19059383 20079455
FOXO1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21149440 23430617
FOXO1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22968147 21335550
FOXO1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16670091 19289458
FOXO1 RPS6KA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12351634
FOXO1 NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18391971
FOXO1 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18375530
FOXO1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25510553 19049975
SP3 GAST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10580833 9271241
TFAP2A GAST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2566164
NFKB1 GDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9729303
SMAD4 HAMP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17187402 16330325
SP1 HDAC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16280357
HNRNPK MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8349701
SMAD4 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19079362 12296825
SMARCC1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RELA IKBKB â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 12842894 5216511
IKBKB TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23589370 33548094
STAT3 IKBKE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22330135
SMAD3 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19265200 18951876
MYC INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799123 1917937
SMARCA5 KAT2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KAT2A SOCS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19339690
KAT2B RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10747963
KLF4 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19531492
STAT3 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129668
NR3C1 KLF9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27777311
TFAP2A KRT10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20500798 10588870
SMARCA2 LAMC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SP1 LAMC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12034813 9403717
WNT10B LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
MAFB MAFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24520122 18199433
MAFB PDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18522939 18199433
SP1 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17889508 16452190
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
MAPK1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
RPS6KA1 MAPK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SMN1 MAPK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
MAPK11 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9776729 11604491
MAPK3 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK3 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK3 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16888388 16691505
MCM3 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SP1 MMP11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22227581
PPARG MSR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9422508 11007963
MTOR RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15060135
PDX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11687580 17317781
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
YWHAE NCOR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8007916 17630505
PPARG NCOR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17011499 8970730
NFKB1 NCOR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17876798
RELA NCOR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17876798
NOLC1 NF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NFKB1 SERPINA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11027208
NFKB1 NOLC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21266110
NFKB1 PTHLH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17554373
RBPJ NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16763620 12700242
RELA NOLC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21266110
TRIM28 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9742105
SMARCC1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 9590696
NRF1 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12958173 18222924
SP1 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19049975 23958347
PPARG YWHAE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19221220 20127524
PPARG SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11861425 11426586
PPARG SLC2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15886523 16395520
PPARG PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18309368
PRKACA SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12809504 19778940
SPI1 PRTN3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8943304
TFAP2A PSMC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19089912 11007955
TFAP2A PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16423197
SMAD4 PTHLH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11590145
RELA PTHLH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17554373
SPI1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22105598 12032776
TTR RBP4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
RELA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
SP1 RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14742449
SP3 RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14742449
STAT5B SERPINA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20702579 8636096
SMAD3 SFTPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12161428 18003659
STAT3 SFTPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15044588 11788590
SMAD3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
STAT3 SLC2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19006119 15194489
TFAP2A SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9786898 7574486
TFAP2A SLC9A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12619893 18951995
SMAD3 SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20123992 21965288
SMAD3 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21294585 11042172
SMAD3 ZFP36 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12754205
SMAD4 ZFP36 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12754205
SMAD4 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21294585 11042172
SMN1 SMARCB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMARCC1 SMARCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1459453 19785031
SP1 SMARCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16288722 15187086
SP1 SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20644166
STAT3 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132009 18447642
SP1 XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17121920
SP1 SRF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10602487 10330138
SP3 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24219545 10446912
SPI1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24429361
STAT3 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11889125
CCNT1 MYC â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
CDK2 MCM3 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 21965652
ATF4 CREBBP â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
SP3 SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12414801 11517158 10825178 16734381 9329821 23825960 12200149 15247906
LRP6 AXIN1 â—¼   RELOCALIZATION ✅ - 0.81 0.81 Signor 18632848
CREBBP FOXO1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
EGFR APOB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24189400 28065597
CEBPB ATF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20110283 20102225
CEBPD ATF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29601799 20102225
ATF4 CEBPB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11018027 20102225
FOSL2 CARM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
DAXX CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24981860
ESR1 KLF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 KAT2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
YWHAE HDAC4 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 8005698 11504882
KAT2B KAT2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10373431 24981860
SMAD3 KAT2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15009097 22995475 11058129 15994459
SP1 KAT2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16050810 15647279
MCM3 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC NCOR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC TKT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
PPARG RARA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 32929351
EGFR STAT5B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 11751923
DDIT3 ATF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
ATF4 CEBPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
BATF CEBPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
BATF3 CEBPG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
CBX5 EHMT2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CEBPA CEBPG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
DDIT3 FOSL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27107012 32296183 20102225 25416956 16189514
SOCS1 FLT3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10022833 29991678
WDR5 KAT2A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 30274785 18838386 26186194 28514442
WDR5 KAT2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 18838386
LYPD3 MTOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SOX2 NCOR2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 28794006 21532573
WDR5 SOX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30089852 29383478 35140242
KAT2A WDR5 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
MAPK3 RPS6KA2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
CARM1 RELA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RELA STAT3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATF2 BATF3 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
MTOR STAT3 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
NR3C1 STAT3 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
AR FOXA1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
NR3C1 RELA â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SP1 STAT3 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ATF3 CEBPG â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20211142 16189514 23661758 20102225
ATF4 BATF â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
CEBPG BATF â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
MED23 CDK8 â—¼   PROXIMITY ✅ 0.84 0.84 mint 25281560
CEBPB SP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12665574 12847250 16651265
ESR1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21984853 31527615
ESR1 FOXA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23403292 25303530 28336670 27926873
ESR1 HDAC4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16051668 19893013
MED23 MED20 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 25281560
RARA RARB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 22022577
CDK8 MED26 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
POLR2A SMARCB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CDK2 MCM3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CREBBP NR3C1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
KAT2B SMAD3 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
SMARCA4 SP1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ATF2 MAPK11 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
IKBKB NFKB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 11158290
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
ATF2 ATF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25609649 26344197 31964530
BATF3 ATF3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12805554 20211142 23661758 20102225
SMAD3 CEBPB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12202226 12524424
NCOR2 NCOR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10944117 11013263 16033423
RPS6KA2 RPS6KA3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CARM1 CREBBP â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
BATF DDIT3 â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
ATF1 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 31527615
ESR1 CCNT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 15940264
MCM3 CDK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16189514 21965652 15232106
SPI1 CEBPA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16983342 12091339
NOLC1 CEBPB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8972203 9553145
SOCS1 EGFR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22973453 12070153 29991678
SOX2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
NCOR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9171229 20392877 12738788 14715875 23403292 9702189
ESR1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
ESR1 RARA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25604459 25303530 9717844
MAPK3 RPS6KA3 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CREBBP STAT6 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
NFKBIA RPS6KA1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CEBPB CEBPD â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 1840554 20102225
EGFR STAT3 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 22693070
FOXO1 PRKACA â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PPARG HDAC4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21605119 12943985
KLF9 SIN3A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 11438660
MED26 MED20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21729782 24981860 15175163
MED26 MED23 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21729782 15175163
MYC WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31767764 35140242 17353931 29467282 30415952 27320920
SOX2 NCOR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 28794006 23667531 21532573
CREBBP KLF4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK8 MED20 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RELA SP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATF3 DDIT3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMARCA2 SMARCA4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
KAT2B WDR5 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
GSK3B SMAD3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21310903 18172167
ATF3 ATF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20211142 23661758 20102225
CEBPG ATF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 12805554 23661758 20102225
DDIT3 ATF4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12805554 23661758 20102225 18330356 16189514
DDIT3 BATF â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27107012 23661758 20102225 18330356 16189514
DDIT3 BATF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32296183 20211142 23661758 20102225 25416956
MYC CDK9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17700062 12944920 30415952 26687678 19818711 11673469
CEBPB CEBPA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 1840554 15751966 20102225
CEBPB CEBPG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20102225 12177065
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
EGFR RGS4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11602604 31980649 25402006 24658140
SIN3A HDAC9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12590135 11959865
KAT2B RARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14581481 9445475 17475621
MAFA PDX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15664999 15665000
SP1 NFKB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33572115 7933095 16740634 18083845
IKBKB RELA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
NR3C1 SMARCA4 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CREBBP KAT2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
KAT2A MYC â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREBBP SMAD3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HDAC4 YWHAE â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MAPK1 STAT3 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MYC GSK3B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16247449 20713710 19131971 21150319 31638140 29467282 11877389 33541412 14563837 8247524
GSK3B LRP6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19107203 16890161 16365045
ABL1 ABL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27229929 12569093 15735735
CREB1 ATF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 20102225 1655749 8384217
FOSL2 ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 26186194 20102225 28514442
BATF3 ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 23661758 20102225
ATF3 SMAD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20930144 12718878 16189514
CEBPA DDIT3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27555288 33961781 23661758 20102225
SMAD4 CEBPB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12202226 12524424 16959612
DDIT3 CEBPG â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20211142 23661758 20102225 25416956 16189514 12618752
HIPK2 DAXX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23536002 19465479 14678985
FOXO1 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11435445 11353774 22266855
ESR1 SP3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10816575 31527615 16651265
ESR1 MED20 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
ESR1 MED23 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
KLF4 SP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12034813 22282354 16713569 9651398
RARA SP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10361124 19401466 16713569 18270252
SP1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10878024 11114293 22227581 12228247 11432852 16714330
SP1 SMAD4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10878024 18215124 11114293 21297662 22033265 16714330
NCOR2 RARA â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
AR NCOR2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CREBBP RELA â—¼   ACETYLATION ✅ + 0.89 0.89 Signor 16382138
RELA CCN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20018891 22253074
ESR1 CCN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11356703 18414489 11840342
RARA CCND3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16189514 12482873 16713569
TP63 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19861536
RBPJ GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MTOR GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
AR GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20127713 20610535 18687691
GSK3B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15361837 15178691 14985354
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
ABL1 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26546517 25944899
ABL1 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19783996
ABL2 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19563810
ATF2 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1387083 8382609 18385943
MYC ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18413597 10500217 18414489
CEBPA APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9921275 1545795 8344962
FOXA1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24875621 18178153
AR PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18386814 16317058
AR TKT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9719026 8807577
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
RELA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16713569 8798655
SP1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2145272 12760745
ATF4 ATF3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20102225 19164757 23661758 16189514
ATF4 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16026328
ATF4 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12057991 21244365
AXIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19131971 20399964
SP3 BTK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11779634 10362515
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CDK2 CEBPA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34002296 11684017 15107404
CDK2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11598016 19450264
MED26 CDK8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 20098423 21729782 23746844 15175163
SMAD4 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12429655 22710759 19419955
ID1 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11427735 11507043 10728702
CEBPD CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10373535 7910803 10623469
FOXA1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19074951
NR3C1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27777311 11279134
CEBPA CPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1511897 9774647 19272383
CEBPA SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14712233
MYC CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
CEBPA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
SRF CEBPB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9032301 11500490 10318842
CEBPB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21098707 20581311 16585579
SMAD3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12202226 12524424
MYC CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21143913 20426839 17471507
CEBPD PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12791769 1714459 11278589
CEBPD CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499410
CEBPG SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1681537 16754198 2404278
CEBPG SLC2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7487103 9806888 12526103
CEBPG INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2404278 9668047 8817653
CEBPG DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15781252 12082616 12069855
CEBPG ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9192779 8756629 12949251
CEBPG NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2023930 1718972 11145742
CREB1 GNRH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18599546
CREB1 NOLC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21266110
CREB1 RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath
CREB1 NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10435592 11175282
CREB1 SMARCA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16675956 20864035
TFAP2A CREBBP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12586840 11694877 11744733
NR5A1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10770490 23358192 9468515
TFAP2A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12586840 12169688 17905638
RARA CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23321499 16417649 21110951
CREBBP IRF9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8848048 17923090
CREBBP STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15649887 11773079
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
MYC CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10229837 11145693
SP1 EDNRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16921166 16623715
RELA EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15964798 21912613 23383347
TGFA EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12297049 24658140 31980649 8663070 10775655 25402006 28988771
ID1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14688027 16525633 15599381
RELA EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17881446 23379415
STAT3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18367518 21590492 23504318
ERCC6 EHMT2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16186106 18656484 12419226
NCOR1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16469706 17400812 12145334 16713569 12738788 21182203 24051437
FOXA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21572391 20501593 24290378
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
NCOR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17591692 23015261 15802375
STAT5B ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11731618 11682625
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
ESR1 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23167795 16423895 19366879
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
SP1 F7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9716591 8618898
FOXO1 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16670091 12414908 17317207
SP1 HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18632985 18850004
HDAC9 NCOR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12590135 16713569 11466315
MYC HSD11B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NFKB1 HSD11B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20427719 15659537
NR3C1 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23161582 9369450 18483179
SP3 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 8776721
RELA IGFBP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18226221
TNFAIP3 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18353649 15661910
IKBKE TRAF3IP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23066157 21822257
MAFB INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16780794 18199433 17360442
STAT5B INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10830280 10821852 10373481
ITGA5 SPP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10673366 8910476 10593924
SP3 ITGA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18775869
KAT2A KAT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23667505 23555303 21559432
MYC KAT2B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 12660246 15572685
STAT6 KLF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22378047 25934862
TP63 KLF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20972454
STAT3 LBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8668165
PRKACA LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21262972 18981475 21406690
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK1 RPS6KA3 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SPI1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22075620 10727414
MAPK1 SP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17685427
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RELA MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK14 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15649893
MAPK3 SP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17685427
MECOM SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23858473 9665135
SPI1 MSR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8007948 7777517
TFAP2A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9632747 8276360 7555706
RBPJ MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18490439 10644343 16847353
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC TKT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8788173 9212167 18414489
MYC PRTN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC S1PR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC STAT6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ZFP36 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC STMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12695333 11085504
MYC WNT10B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
NCOR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22395773 20462215
RARA NCOR2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11929748 16219912 19377461 9256429 7566127 17475621 9380707 15604093 20543827 16713569 10082574 9415406 25303530
NCOR2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22395773 21846906
SIRT1 NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22395773 15175761
NFKB1 STAT3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25241761 12057007 16713569
SP1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20427719 20538607 9151857
NFKB1 TNFAIP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11880364 19343319 10807933
RPS6KA2 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20385620
TTR NGFR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SMN1 NGFR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SP1 NGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11839795 19114034 21123453
SPI1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16263717
TP63 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
TFAP2A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9015328 7794935
NR3C1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12734399 9261164 9442377
SMARCA4 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 10688647 9590696
PPARG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NR3C1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NR5A1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8825555 12697703 12697699
SIRT1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15850715 21633182
PPARG RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12839938 18075297
PPARG PTGES â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15868626 15023995 17186945
SP3 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9415398 11578973 11562358
TFAP2A PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7958425 12169688 16790435
SPI1 PRTN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8943304 10677505
STAT6 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17237818
RARA SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21310893
RELA TNFAIP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11880364 19343319 10807933
STAT3 SERPINA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17461989 7619083 8636096
SP1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23843607 20160399 23704280
SP1 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21421563
SMARCC1 SMARCB1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24421395
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
SP3 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19481140 22827437 14744778
TP63 STAT6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
AR NCOR1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CCND3 CDK2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HDAC4 NCOR1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
MAPK1 RPS6KA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CBX5 TRIM28 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CDK8 KAT2A â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 29568061 18418385
AXIN1 LRP6 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CCNB2 CDK2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CDK8 MED23 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CDK9 POLR2A â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CEBPA TRIB1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ERCC6 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CREBBP RELA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
ATF4 CEBPG â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
CDK8 KAT2B â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 29568061 9710619
SMARCC1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
EGFR STAT3 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ATF2 MAPK14 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
HDAC4 NCOR2 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
NCOR1 SIN3A â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 17210713 16713569 11430826
SMARCB1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
RBP4 TTR â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
POLR2A SMARCA2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CDK8 POLR2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
IKBKB NFKB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
POLR2A SMARCA4 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
CDK9 CCNT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 14627702 23455922 19914168 30652970 24981860 14580347 21697490 20535204 11713532 22939629 26659056 22959624 11145967 16980611 15713661 23602568 12115727 11689688 17643375 10574912 9499409 12832472 20305087 30649429 26344197 10617616 27684187 18483487 9872325 19818711 16109377 12894230 15328539 12944466 15546612 32707033 15713662 20153263 19387490 18566585 22483617 21729782 20562857 24367103 28514442 15528190 10465067 11713533 10958691 9491887 17700062 23064645 26186194 11282025 12588988 15107825
EGFR EGF â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 25453753 30083275 21822280 12620237 19531499 25080504 12093292 22729867 23597562 18427122 26280537 18271526 10970856 15620700 11684674 21439278 8663535 28988771 2790960 10788520 10085134 16274239 25241761 17697999 9135143 12297050
NFKBIA IKBKB â—¼   PHOSPHORYLATION ✅ 0.97 0.97 mint 8209688 16126728 506093200
NCOR1 NR3C1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
EGFR TGFA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
SMARCA2 SMARCC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CREBBP PPARG â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NCOR1 PPARG â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
NCOR2 PPARG â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
SMARCA2 SMARCB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
MAPK1 RPS6KA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EGF EGFR â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NCOR1 RARA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CREB1 CREBBP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NFKB1 NFKBIA â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
SMARCA4 SMARCC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
IKBKB NFKBIA â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCA4 SMARCB1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCB1 SMARCC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
AXIN1 GSK3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFKBIA RELA â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNT1 CDK9 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCN1 ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9446626
SP1 TAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15706661 7621073 9566873 2657100
STAT3 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16084951 18310224 15184887
GSK3B CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 11152665 20537194 10385618 15252116 11124803 16331257 12969793 19757160 16732330 10486203 16039586 14536078 18167338 15326477 12459251 12615961 17092340 15212693
RPS6KA1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11584304 11583116 23331499 8250835 7980435 8524413 24931005 19346560 12054501 16039586 12147701 11035810 22615844 16543730
MAP2K1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17081983 21105670 16964243 14617795 30711629 18547980 8382613 17188038 17192257 15020233
MAPK3 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16039586 28646232
PRKACA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16543730 15845746 18691976 19836308 8524413 12054501 16039586 12147701 16522636 11035810 18669648
MAPK14 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26822034 17726008 21303975 18451303
MAPK1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16039586 28646232 18451303
GSK3B CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20194724 23181522 28775290 10567568 21038412
GSK3B NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 26999213 12871932 11425860 24618402 18669648 17693123
GSK3B CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22369944 22355693 16055922 17601773 15985551 22080951 23046544 17570479 15985552 19940121
GSK3B AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 102.0 1.0 Omnipath 20128690 16944320 11738041 20043192 12511557 11967263 16890161 22613765 14663202 23602568 8524413 24451375 19303846 12554650 8638126 22509369 18593713 16199882 21988832 23331499 19759537 10428961 9482734 22270359 19202075 17570479 16293724 15327768 10581160 17318191 11487578 22773187 26496610 16568235 17318175 19131971 15465828 26912724 25241761 24976009 21242974 22682247 10228155 23579495 12584189 23959799 15020233 10421629 10488109 11278246 9501208 18632848 10481074 10535959 10318824 9554852 17601533 9832503 21502811 9734785 23455922
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
GSK3B MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 17081983 18463697 21646472 30037819 26751215 25647305 2663470 20080742 19797085 30003124 16855632 12040186 18679417 11018017 23331499 29229669 16611981 21071413 24265759 20068231 10671551 16039586 17570479 16023596 29258530 12615961 18669648 21113395 22461507 19131971 8247524 16247449 20604938 19575820 15150404 22481935 23668310 19651622 17444818 23964270 20537194 22893788 27684546 24662831 25333250 20399964 11877389 14563837 18408012 17052453 18455992 15212693 16371461 11274345
GSK3B PDX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16407209 19833727
GSK3B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16568235 12162494
GSK3B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18201972 15465828 15280197 22761446 20537194 21194439 19345186 21660967 19997086 16407239 25629551 17183360
GSK3B NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 30250038 18838540
GSK3B HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21118993 18045992
GSK3B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 18172167 21071413 21310903 23077590 28756206 19114991 19002158
GSK3B LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 22357953 23331499 19107203 21606194 16890161 21709260 16340998 16365045 19366350 21406690 16341017 17318175
GSK3B MAFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18042454 11779503
COP1 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11051551 11536016 11432859 15383541
SMAD3 ARG1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 6357187 8515656 8871614 9389648
SMAD4 ARG1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 6357187 8515656 8871614 9389648
KLF4 ARG1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10432118 10925299 12193690 21093321 21670502 23390297 6357187
CEBPB ARG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9013624 15922518 19805133 8612622 23913966
SP1 HDC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16949047 16357063 17827213 14670968
CREB1 G6PC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20022930 12760745 17635106 15388792 11544200 26652733 19583954
NR3C1 G6PC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22457708 16037130 26652733
FOXO1 G6PC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16840535 11672436 11467835
FOXO1 G6PC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15047713 12130586 22296760 22384829 12373635 16308421 10960473 21081708 16492665 22521266 16804074 23995837 12556524 11467835 12507516 18805788 16037130 20577053
ABL1 BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 12445832 15212693 12573241 8629002 17932028 10051622 25704810 8630736 34162728 9188445 16497976 20841568 27602755 11598012 9326643
ABL1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8940193 16846476 20841568
ABL1 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8940193 20841568
ABL1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30323259 25368164 26385316
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
ABL1 ABL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12569093 15735735 20841568
ABL1 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21071413 23331499 10753870
ABL1 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8940193 20841568
ABL1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14757045 20841568 12167702
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 ERCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17626041 20841568 27827925
ABL1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19563810
SP1 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24315822 7829523 15576380 2677669 1846185
TFAP2A ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8610173 9571041 7559515
SMAD3 ACTA2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD4 ACTA2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD3 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21990365 15306544 17303001 16858008 12702545 24446247 19261809
SRF ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18337547 12505862 17303098 19269978 19608972 20093628 15576380 12530967 20016221 24446247 22461426 14970199 15269336
KLF4 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16858008 23646205 22241174 18511453
ALK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17145710 10918587 9305919 8272872 12626508 16084951 15592455 23331499 12576423 11350938 11294897 14968112 12244095 9083098 8626374 9566874 11940572 11429593 14551213 11850821 15212693 9582023
CEBPA AMELX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16595692 10859305 16674681 17704518 10766866 23398885
CEBPG APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8557677 1545795 2161847 2258060
NFKB1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14576180 15517885 20159994 12165860 16619263
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
RELA AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24466341 16619263 14576180 15517885 14715080
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
NCOR2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19223455 16373395 21720703 22508987
AR ATF6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18511414 8580999 7522959 15590903 14662770 18692155 17374439 18212060 20610535
AR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15305378 19318561 21613411 19258514 15650253 17242169 18692155 15288768 11556855 20610535
AR SMARCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535 17721441
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
AR CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9822653 15350180 16492776 16344550 11161315 18819102 18031230 20610535
AR KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18945670 20610535 11328859 23095762
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
CREBBP AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20541699 9822653 15691881 12810069 9482849 16713569
MAPK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18511414 9725910 10318905
MAPK14 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30644418 24424504 21820033 16282370
CASP1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9535906 16713569
CASP8 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17170703 9535906 16713569
KAT2B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504
SMAD3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 11248024 11280774 12226080 16713569 11707452
NCOR2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 23331499 11923464 15062576 14593076 17356171 22508987 12441355 12771131 20812024
FOXA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23260764 22722839 16713569 12750453
DAXX AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 27671201 17145710 15350595 15572661
AR NR5A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 11518799
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
AR NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15598662 11971970 16469706 14593076 15256534 23518348 16713569 12089345 16914745 20812024 20974212
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18358509 12534934 22260327 15288768 18951974
AR FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18391971 17202144 16713569 12482965
PRKACA ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8384217 8663317 20068231 11018520 11335727 11909979 9016641 12414794
ATF2 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10909971 17337306 21278380
ATF2 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12833146 8576171 20581861 10979959 18719024
ATF2 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11901151 17591797 11278336 12057991 16007171
MAPK14 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 17081983 18767875 21098032 20506250 26359454 19690332 11060298 19413330 12788955 10085140 22037767 11566021 17079470 19647037 10581204 10777545 7535770 23331499 7839144 19324872 21071413 21614932 20068231 16393692 15304344 17570479 17380123 18988627 7737130 18669648 15187187 9305639 7737129 15140942 602896 11896587 17548358 12110590 7824938 8663524 33893075 12024021 11078583 11971971 9707433 17258390 10821277 19651622 19436832 11259586 27726305 11781825 9430721 27142525 10909971 12118074 15569672 15212693 9753474 11274345 10903740 26987986
MAPK1 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10777545 17081983 21098032 9430721 12110590 20068231 19690332 15304344 19413330 10878576 15192015 7737129 18669648 19647037
MAPK3 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10777545 12110590 20068231 15304344 15192015 19647037
PRKACA ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1661585 15105425 92095966
MAPK11 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 17145710 17081983 20506250 19690332 19413330 17079470 11566021 10085140 17254968 10777545 7535770 7839144 21614932 16393692 15304344 17380123 7737130 15192015 18669648 15187187 15140942 9235954 12110590 17258390 19436832 9155018 9430721 9029150 14734562 11274345
SMAD4 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085140
ATF2 ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12833146 20211142 20102225 23661758
SMAD4 ATF3 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
SMAD4 ATF3 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
ATF3 ID1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16713975 16831886 17490644 18832382 21614932 23850759 9389648
SMAD4 ATF3 â—¼   UP_REGULATES ✅ + 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
ATF4 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10085237 16246168 21801305 17042743 22819556 23269699 25681212 16989641
ATF3 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9343434 14729979 22753726 10085237
MYC ATF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333 23612979
ATF4 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16006626 12082616 10085237 15775988 12083523 16246168 18940792 20020050 17276738 20732869 21044953 22802018 17726049 21966512 17455323 22691366 31226023 24939851
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
RPS6KA3 ATF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23975372 15109498 22052162 27321283
ATF4 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11564156 9295363 25241761
ATF4 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12805554 20102225 18330356 23661758 16189514
ATF6 HSP90B1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17991856 18360008 23850759 26587781
ATF6 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 31226023 17455323
NR3C1 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11216640 10329476 9694812
MYC AXIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC AXIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
LRP6 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20128690 23331499 8666229 12897152 10428961 24976009 16890161 18632848 22682247 23959799 16340998 18988627 19107203
AXIN1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11438668 23331499 18988627
BTK LY96 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
SPI1 BTK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8934542 8562928 10362515
SP1 BTK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11254710 11779634 7721790 10362515 8562928
BTK NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12909638 30887112 12167702
CAMK2A CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1314426
CAMK2A EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17389395 17081983 3138233 20166139 10347170 15901825 16799092 18691976 8226933 20068231 1309762 7805884 92065884 1956339 7505275 18669648 15302935
CAMK2A CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11175347 12356771 15733869 1646483 11160957 9668047 7958915 9829964 12235136 11970864 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11013247 11909979
CAMK2A NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22888005
CAMK2A STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 7925472 26317901 16554300 14645234 26087399 20110360 11015208 27130664 31546234 11058583 8245003 16982419 27041561 30786936 10913145 9271428 7775478 8125092 9686569 19359244 30320402 21768358
CAMK2A SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11859076 12171911 10753652 12684542 8413226 10318869
CAMP PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23109003 15539636 7935349 16460834
ESR1 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
FOXA1 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
CARM1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15731352 11701890 12374746 17043108
CARM1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18188184
CASP8 LY96 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 21737330 12752666 15814722 16115877 14739303 21737329
FOXO1 CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20200974 19050291 15632117 15565601
MYC CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15367674 12695333
MAPK3 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 24342355 17290218 26036637 29233910 24484936 20937773
MAPK1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24342355 17290218
MAPK14 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14970175
RELA CCL20 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12414801 11749970 21852561 22319003 21825016 11581170 19303953 19324905 22240809
MYC CDK2 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
MYC CDK2 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
CDK2 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10197981 11283614 12193595 14536078 15147722 15241418 15279786 16156666 17055429 17303408 17660363 18590585 18636226 20027199 20713526 2191300 28536364 7575488
CDK2 MCM3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
MAPK1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10962581 12359725
CDK2 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17601773 22369944 17570479 20818427
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CDK2 PTHLH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12504010 10373465
CDK2 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 21106439 19652536 7575488 18590585 17522590 17303408 27035875 19473886 24948874 15677884 15279786 23029264 19124971 17660363 17038621 20148668
CDK2 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7575488 18590585 17296725 17303408 21965652 30062004 17102137 17116885 19793801 17582221 15232106 16189514 17660363 15279786
CDK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8386367 27653698 17081983 19966300 18669648 29896817 17570479 20713526 17558397 15103331 22348395 20445224
CDK2 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21602882 18769144
CDK2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 10197981 15241418 19218245 25241761 15520018 20068231 17099224 16156666 16189514 19413330 14512875 12193595 15212693 19114991
CDK8 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
CDK9 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
CDK9 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 22053051 20222012 25023704 14662762 10364292 20106982 18066052 30135578 24385927 18644870 18329373 14517250 20932174 12052871 20226668 19575011 8416977 11575923 16735508
SP3 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10649433 7592908
SMAD3 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14647420 15326485 23032366 16819512
MYC CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12244100 22610535 11804592 12565816 19164764 12835716 11283613 14519204 24618291 19201832 23722468
SP1 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10649433 16298343 11804592 11013220 20121949 7592908 21872590
SP1 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 11013220 10454538 9670020 11283613 11074002 11283614
FOXO1 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10454538 11283614 9308237 17936558 19380174 10783894 11283613 17873901 20673124 11094066 15668399 17646672 21708191 15084260 21613825 17940099 11994454 11154281
MYC CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10454538 10373560 9308237 17936558 12738781 17873522 11283613 21406394 9312026 15095404 10504341 17558397 20551172 19901969 19815509 11283614
SMAD4 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 11013220 10454538 9670020 11283613 11074002 11283614
SMAD3 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 11013220 10454538 9670020 11283613 11074002 11283614
CEBPB CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9990015 19581927 10603305 15509789 16431920 19663997 15110775 7862113 10854425 17301242 24216764 20179325 15158467 17646392 18622014
DDIT3 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 7588595 21983012 11050169
TFAP2A CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19089912 11688971 11050170 10588870
MYC CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15681429 17082780 7556187 8076602 20097210 12695333 15867211 19259613
CEBPA SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17671233 24429361 14636649 20972335 12949251 14592841 12032776
CEBPA SFTPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11912209 11596110
CEBPA HAMP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18671304 16946298 18326822 12183449
CEBPA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22553076 20725087 15664998 15110775 18619497 19059241 9367890 15158467 23071089 10862621 15632071 16580992
CEBPA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20506344 12914528 10956548
CEBPA ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17360796 19620402 8756629 16247445 12949251
CEBPA SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18408001 23647459 20698834 16754198 12641495
MAPK3 CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 20101026 14701740 26515730
MAPK1 CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14701740
CEBPA SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10397723 12091339
STAT3 CEBPB â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
CEBPD CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7646815 18703634 7910803 11559710 18092000 1741402
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9353292 21063109 19164449 10649437
CEBPB PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7559624 11259631 18367585 11095928 14966110 12914528 15221958 18294142 11668179 17556653 10652293 21150337 20506344 18820298 18650268 16786175 10631313 10841183 22369775 19908286 16820889 11522796 15713664 16699180 16399783 10956548 11278846 10724331 16981245 18444174 14645533 16452236 12086405
CEBPB CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17067998 8654374 10818089 15722556 15388792 17599912 12857754
CEBPB DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8051100 16757577 10085237 8662954
CEBPB PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22473998 23934183 7557387 12524424 16431920 22610404 15110775 18694725 17242167 16054042 15158467 9950217 10862621 20829347
CEBPB SFTPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11912209 11596110
MAPK3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 19327116 19443782 15212693 15367685
MAPK1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 21980398 19443782 17570479 19413330 19723873 15367685
NR3C1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25202013 9817600 9428795 11279134
CEBPB STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11134330 18266962
CEBPB FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18391971 11893744
STAT3 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10867011 17471507 24011072 15389878 15486993 9163525 25787076 15930175 9528783 16293640
NR3C1 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10649448 1840554
SP1 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17965828 9528783 20506344 17471507
CEBPD PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7559624 10841183 19908286 16256955 20506344 10956548 18820298 16397300
CEBPG SFTPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11912209 11596110
CEBPG PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18362203 15221958 11673276 10692422 17524357 16256955 11522796 16399783 21104307 11133817
MAPK1 CEP55 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 19415658 17081983 29743530 19691289 18767875 18691976 19664994 20068231 18452278 19413330 16964243 18669648 16198290
PRKACA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 28003367 23060444 25867080 21455600 30600261 1716180 28242698 19328185 32102849 92316961 19095655 14602047 7530719 10581361 11053017 9385646 25330774 15657296 1377674
SRF CREB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 15733869 28286024 15542842 9770464 1833716 18088355 7823924 7551568 15449318 2040600
CREB1 RELA â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
CREB1 PTGS2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11579131 15187187 15749884 16007092 16713974 17404308 20547845
CREB1 PRKACA â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 19244110 12150772 12082174 2573431 9733829 17908236 15879576
CREB1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11160957 11698596 12842905 9770464
CREB1 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11160957 11698596 12842905 9770464
CREB1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11160957 11698596 12842905 9770464
CREB1 RELA â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
CREB1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 20954072 21668646 15213229 11092885 18515110 19925797 22919060 17559081 16007171 17505916 17186551 15221958 11668179 11526505 24378735 20032081 17524357 16256955 19797430 16319525 21268077 15289885 17632087 17962194 14645533
CREB1 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15319449 11081181 21586695 24078059
RPS6KA1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 11175347 12356771 15733869 11160957 11544482 15138267 11532940 9829964 7958915 10558990 12235136 11335727 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11909979
HIPK2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20573984 19690332
MAPK14 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11175347 12356771 15733869 11160957 11532940 7958915 9829964 12235136 16189514 11335727 9687510 8887554 11698596 23532963 8688081 9528766 11018520 11969286 11377386 11909979
PRKACA CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11175347 12356771 15733869 11160957 21902831 2885756 2875459 7958915 9829964 12235136 12763014 9687510 8887554 15568017 11698596 8688081 9528766 11018520 11969286 11909979 8336722
NR3C1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20203101 16713569 8449898 7621901
RPS6KA2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 9829964 11698596 11018520 11160957 11969286 12235136 7958915 9687510 11909979 8688081
RPS6KA3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 9770464 9829964 11018520 11160957 11698596 11969286 12235136 17570479 7958915 9687510 1545823 11909979 8688081
CREB1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 10866654 18599546 15585582 7870178 8028671 11313407 16007092 8413673 11564156 15691881 9829964 15073328 20403362 11259575 17476304 17707401 20541704 16799563 7870179 11123304 27789289 7913207 12933667 8663317 8004670 11483993 12198160 9413984
NCOR1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20462215 17400812 12392082 10612426
SP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23297421 20096088 9765204 21191649 21464950 12200429 20130956 12169688 15576380 15184875 15713621 18571793
KAT2B CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9687573 8684459 9687513 9445475 11864601 9267036 17496784
CREBBP RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10542243 14597638 18241676 17138826 15140884 9096323 16713569 12456660 10454579 16382138 19608861 9806899 25314079 11931769 12163591 12881425 9659924 15171256 9548485 16291753 17362989 25733689 17434128 15334063 15806143 10235267 17296604
CREBBP SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15849193 10497242 15467747 18003620 9679056 15990875 15750622 19589780 17074756 17283070 9679060
CREBBP STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11509556 15695802 11574547 10454341
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
STAT3 CXCR4 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
RELA CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20068066 12690099 16267013 20157762
ESR1 CYP1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16972788 16010691 17511620 15858227 15837795 20716622 22837390
MAPK1 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15616583
MAPK3 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 25241761 15616583 26769850
RPS6KA3 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16213824 18974095
RPS6KA1 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16213824 21785723 18974095
DAPK1 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18283219
HIPK2 DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 19465479 14678985
MYC DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15021909 18483244
MAPK11 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15187187 19436832 15140942 20506250 8650547 21614932 16393692 11274345
MAPK14 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15187187 19436832 11163539 23331499 15140942 20506250 8650547 21614932 16393692 17570479 11426938 16189514 11274345
EGF EGFR â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
ESR1 EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10894157 15075211 20889718 8770893 19423651
EGF EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 131.0 1.0 Omnipath 17145710 17081983 21822280 20813200 23613900 9135143 25453753 21303971 10209155 26821125 12297050 27387652 25241761 30083275 12093292 30197274 21649524 19531499 18762250 16729043 26921391 17697999 17575160 21722395 12620237 19129184 10788520 23331499 3494473 15620700 14568001 15958209 24096486 18253097 16843263 18320059 21532939 10085134 22260327 15708576 26280537 23912460 21858221 11116185 10970856 27462018 18427122 25080504 20953304 19135477 11684674 8639530 27564112 18270696 2790960 17971399 23185569 19895983 28988771 29617357 23597562 19531623 23950932 21071413 8663535 6289330 16274239 17563729 21439278 20458382 22216880 18271526 12771140 21311755 24709886 25366117 12648462 21107857
PTGS2 EGFR â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18633355 20138012 21847358 23010081 23390297 25987127
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
PPARG EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15486348 18332871 18288266 23370527
TFAP2A EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16449191 8621697 14522076
NFKB1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14678988 18367518 12469217 17881446
TGFA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 21722395 28988771 25402006 23155381 3018723 23331499 16585207 10209155 24658140 10775655 31980649 12297049 8663070 12648464 27635238
MAPK14 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15187187 18039929 19138820 7535770 12738796 17139251 16932740 23397142 16785992 11274345
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
MAPK3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 1651322 17081983 3138233 15901825 16785992 1939237 91332050 27531070 17570479 2543683 2115882 34086370 17192257 1651323 15302935
MAPK11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15187187 18039929 12738796 16932740 11274345
EGFR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23956138 12070153 20145033 14967450 20032199 21573184 25402006 10358079 23894143 14966128 24135280 25241761 14963038 24189400 15657067 24658140 15485908 15950906 18258752 31980649 9756944 22693070 12873986 15951569 15284024
EGFR MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12556561 15531749
EGFR STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10830280 10358079 12411494 10558875 16729043 17016520 11751923
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
SPI1 ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9689920 8756629 16247445 9192779 14732495
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
ESR1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18234909 11522780 9869301 10428965 12761896
ESR1 TGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11145955 8360257 11517191 10828826 22488924 18414489 9667651
ESR1 NRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18048642 21486948 23892277
ESR1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8300756 8912864 8732679 11038749 15831516 15870697 10076999 9626663 18414489
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 OXT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 6153132 9397958 19215399 8076833 10411324 12047722 2108152 15842231
ESR1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20616010 20068169 16950141 21029304 19433249
RPS6KA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10949034 15528270 19925796 15461668 25336146 11139588 12118371 30034315 15059947 16076840 7491495 12093745 11432835 10411321 11507039 9528769 7838153
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
NCOR2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12738788 14715875 9171229 9702189 20392877
NCOR1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16469706 12738788 12145334 17400812 16713569 21182203
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
RPS6KA3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11139588 23936765 17570479 19925796 11432835 11507039 19112174 9528769 7838153
ESR1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 17641689 15831516 9717844 9841885
ESR1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17145710 18391971 22266855 11435445 11353774
PPARG FABP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17322100 9831621 8943212 23805908 10935488 11574398 10425206 21047783 20656057 16854242 20160124
SPI1 FLT3 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10734131 11672593 11964313 12032143 12803886 12811837 16283355 16418395 20510871
FLT3 STAT3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10477595 14670306 15253381 16418395 25215878 8920882 9268501
LY96 FLT3 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
FOXA1 TTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8931989 9512550 8029022 11544200 7862129
FOXA1 SFTPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12161428 19096034 18003659 9006959 11053014
FOXO1 PDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12219087 21533167 12488434 17510498 21335550
FOXO1 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10385407 10358014 10358076 17609436 15200677 11733864 23603247 11570877 17426286 12493691 21401636 17923482 10702299 12163409 16690806 24174424 15987820 10973497 17341623
FOXO1 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19049975 23370526 16783365 28270795
SIRT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 24003218 22013015 14976264 18235501 15220471 14980222 22395773 15788402 15692560
SMAD3 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18391971 15084259
FOXO1 IGFBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18391971 10913147 10358076 9707622 18056423 10358075 10102273 18985696 12493691
FOXO1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16670091 12966085 17317207
SP1 GAST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7890769 14670968 9852054 8920679 10751319 8943318 9144414 2566164 15613302 10679190 10580833 21083750 7721790 17889508 10448078 10075714 22593272
STAT3 HAMP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21289291 23703590 16946298 16835372 18671304
MAPK3 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11259409 16564677 11231586
SMAD4 ID1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16713975 16831886 17490644 18832382 21614932 23850759 9389648
SP1 ID1 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
SMAD4 ID1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9389648 18832382 16831886 11074002 17490644
SP1 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9329821 8544848 2849945
TFAP2A IGFBP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15956342 7559606
IKBKB LY96 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15064760 15814722 16115877 16603398 16547522
IKBKB NFKBIA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
IKBKB RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
IKBKB NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
IKBKB RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 135.0 1.0 Omnipath 15280197 17785205 27329558 22110409 22753932 22205033 21765477 15611068 18519641 15858576 25241761 33579825 23536830 28122346 19393267 34556881 24442433 14560022 15192014 21242976 16840782 19609947 33789981 10521409 26826124 21492457 19110719 23303310 16105840 22212641 26587973 34219129 15210811 16046471 11359840 27626700 15128824 28416608 17178723 21674813 17362989 28737909 19377466 15980040 16407239 15849198 20507904 26082493 15557193 34082140 21798539 26267322 29363544 12767944 20224721 26307684 12842894 17108032 26170389 24336331 27315556 31980577 11259436 34380537 20872791 21674474 15465828 15994321 17548605 26603838 16148147 25136068 33914760 26569329 22234699 17012367 14636585 22039465 32123095 15212693 27466442 33883226 15611276 22081069 19197368 17070014 20051109 26693062 14963024 33971703 28381553 33459422 27244888 18544167 18922932 20188669 15485852 20696864 22689577 17982102 20410276 15489227
IKBKB NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 31598684 11976329 16713569 10469655 29485707 26999213 12842894 10835356 27187478 27402796 18782567 27554194 12482991 25241761 10022904 15199157 19519322 15489227 19250910 15212693 11158290 11297557
IKBKB NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 164.0 1.0 Omnipath 18593939 17145710 18375836 11087742 16793322 11527961 28086098 21232017 12429743 21423167 17693123 21399639 15836773 16177806 9721103 29139553 9271416 17561400 11923072 10889159 17706453 10723801 12791687 11858955 22037600 16365431 10421793 25133483 10398585 9346484 9346241 11158290 18539148 23328071 15574499 21765415 16818647 8657102 18202307 16737960 9315679 21490922 9252186 20001801 15919917 16495515 11368781 16291755 24386391 14743216 25759022 10329646 10882136 16153868 10195894 14751757 18981174 10807933 16007147 7796813 9632633 15856023 17965022 25753787 10783893 10602462 27682876 16965765 15084594 19196987 17322026 12138192 10723127 15210742 16319058 15217903 15218526 7878466 9914500 17367806 9520446 15214841 16846590 12514169 18657515 12403772 10527519 15145317 16888014 16493424 17047224 9135156 15024091 16023083 10593898 14636585 22579987 9214631 24911653 7862124 10320352 16970925 23707515 9346485 12949498 17363905 12486103 9891086 8601309 10880512 7739562 16286467 23109003 9689078 25595906 15371334 16285893 11356195 29145629 23970940 10085062 11815618 17468758 17615396 24586253 17072322
IKBKE LY96 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12692549 15210742 14530355 17526488 17047224 14703513 19656901 17823124 23453971
IKBKE NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 10783893 18794072 8657102 8601309 15939554 12138192 10329681 10882136 9721103 12403772 21171089 16888014 15879144 20717897 16007147 7796813 11815618 10421793 25133483 21872579 10398585 16199137
IKBKE RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 28317833 12842894 16046471 20188669 15128824 17561400 17003035 30223576 15485852 10521409 15489227 15849198 16407239 26025205 15212693 12767944
MAFA INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 51.0 1.0 Omnipath 15664999 9604866 19785038 21063109 17449132 17149590 19502415 24258027 15944145 15650027 21565207 22172402 19576197 15923615 14765989 18506085 15993959 14680841 17927952 17259388 12368292 23775071 17583797 16780794 19264802 22968147 23382704 23737644 15664997 15862113 16505238 23927931 19029092 22466807 17569705 17785922 15665000 16461554 21278380 22974359 12917329 14973194 18515495 8584024 21830322 8289826 17300753 17360442 9414097 24472553 19689288
PDX1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 134.0 1.0 Omnipath 10636926 10567373 19275670 15664999 10748090 10393088 10440129 15944145 17312465 9453241 23796517 15180990 12150938 16148004 12426319 12099699 9199333 17991720 22968147 23737644 11423476 23153982 7575438 17512083 15743769 10331405 16461554 22974359 17299038 18951876 24472553 16901969 9604866 10720084 20943817 18252719 15001545 7491105 12684063 22172402 8986763 20886630 22028710 15993959 11309388 11428722 10924326 16675598 15862113 12783165 10385428 11316746 9252422 16141209 16887799 10629047 15885879 8988180 20007976 10868963 10545531 22150363 9873045 20531294 16055439 18274620 11477691 9649577 12606496 11834725 10545530 12665509 15166251 8697303 23853095 12475772 20339896 7568086 21393239 17150967 16280646 17259388 19264802 10485916 15664997 8922372 23927931 22570331 21540283 22167125 10426567 21335550 21278380 11003654 17299998 23703573 8483904 15496408 18360684 21063109 17449132 7708065 22253604 10585868 16543365 10905482 1944296 11181516 7937976 21076579 18772243 8954967 17927952 7901001 23434589 23382704 14550306 15790780 9637677 10672004 11457885 12193567 17569705 12130581 17785922 20811152 17627512 17706592 8799146 17991758 11549279 19689288 9230347
SP1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9348238 17446237 23626778 18664368 14744869 15001547 23027183 14998783 17449871 15330762 19485892
ITGA5 PLA2G2A â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 18037882 19161977 19454690 19487819 22067905 22470492 24202395 9003039 9456329 9763606 9973479
SP1 ITGA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22227038 18775869 15825163 24130169
SPP1 ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7592829 16713569
KAT2A SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 11058129 15009097
KAT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11804596 19407812 15522869 12660246
SP1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20130956 20144149 17882273 15647279
KAT2B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11058129 15994459
STAT6 KLF4 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10485906 12223527 12244147 14610620 15634881 23124025 24204259
KLF4 PPARG â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10432118 10925299 12193690 21093321 21670502 23390297 6357187
KLF4 PTGS2 â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 10432118 10925299 12193690 21093321 21670502 23390297 6357187
MAPK3 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17496910 18039929 19541618 21965663 20974802 19565474 15547943 12063245 12738796 11226259
MAPK1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17496910 18039929 19541618 21965663 20974802 19565474 15547943 12063245 12738796 11226259
SFTPD LY96 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16834340 16754682 16213021 18990700
PDX1 MAFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21081123 15664999 9604866 17510498 17259388 16461554
MAPK1 MAFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18535013 29339498 23660596 11416124
MAPK14 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15187187 18039929 12738796 11274345 12697810
MAP2K1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9305919 7719937 7568001 10602027 12681450 7719938 7544001 7528668
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
MAPK1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
SP1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12220517 16797880 20506264 20121399 20882567 18372343 10727414 21170990 17889508
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
MAPK1 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12721286 15212693 14517250 14662762
MAPK1 RORA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17512500
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 25409419 11733495 16574647 9099735 9030579 15507114 26670611 17570479 17998334 18596912
MAPK1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12351702 18669648 9199329
MAPK1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15073167 16888388 16691505
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 ZFP36 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7768935 95286626 16262601
MAPK1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12801888
MAPK1 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20058876 15253667 25162926 27049728 18669648 17209041 18088087 20068231 11604491 23602949 18701649 23678047 28554535 19415658
MAPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8939914 12832467 9915826 17906627 32296183 19282669
MAPK1 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17081983 32814053 20385094 11532940 7601337 23331499 15342917 8939914 21071413 23047924 20068231 11335727 9687510 12618428 18988627 18669648 23519423 23109003 18691976 12594221 9915826 17906627 8202512 9430688 19651622 12832467 11500364 14966081 29997244 25730857 8387505 10411321 18212344
MAPK1 NR5A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10230405 14594453 26005698
MAPK1 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21988832 18156174 12016217 25241761 12832467 23602568 8939914 10480933 9915826 17906627 10980595 10856237 19282669
MAPK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 59.0 1.0 Omnipath 18448488 19413330 11335711 9343414 15465816 25584415 12576423 11350938 20068231 12681450 12763138 9872331 11780390 18491316 18669648 11404481 10521505 18691976 20058876 15979846 14551213 10446219
MAPK1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19218245 18032789 18729074 16156666 19914161 23331499 19914168 24080014 8226933 14512875 15520018 20736297 26497676 12193595 26297431 18988627 8388392 10197981 15241418 18775330 9604935 9380693
MAPK1 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 26881937 20630875 22028470
MAPK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19318349 20882567 16377629 18775330 8226933 14744793 16079281 11904305 9604935 15212693 14593115 8388392
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK14 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 25847991 12351702 28582465 31974640 20047289 22911818 19841061 12000743 15817653 20660302 17570479 22401993 17440046 17185395 24024586 19812390
MAPK14 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 10201984 18691976 17502367 17570479
MAPK14 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 10197981 15241418 14512875 16156666 15520018
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9776729 20068231 11604491 18701649 18669648
MAPK14 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12842894 15128824 15485852 10521409 15489227 15849198 15212693 12767944
MAPK14 ZFP36 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25815583 20599781 17570479
MAPK14 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14580335 16410802 8622692 8668171 9724653
MAPK3 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MAPK3 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12351702 17440046 9199329 20047289
MAPK3 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 10197981 15241418 24080014 18775330 8226933 16156666 9604935 12193595 8388392
MAPK3 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 15342917 18039929 12832467 23109003 8387505 14966081 9915826 21071413 17906627 9430688 11335727 18988627 11532940 10411321
MAPK3 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12721286 14517250 14662762
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
MAPK3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28115363 12801888
MAPK3 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 72.0 1.0 Omnipath 17081983 18767875 9731215 20230923 17693683 11135364 19413330 8314790 19664995 19415658 16083285 20068231 18452278 9712920 30628717 94064639 1737801 18491316 18669648 8144611 8245003 26505358 17287340 16094384 19033656 19651622 20058876 8376365 8325880 17924679 19162178 19664994 18707149 25692552 8125092 16964243 18212344
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
MAPK3 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18156174 25241761 12832467 8939914 9915826 17906627 10980595 10856237 19282669
MAPK3 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 23602568 8939914 12832467 17906627
MAPK3 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18596912 11733495
MAPK3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 18448488 19413330 11335711 9343414 23331499 15465816 25584415 12576423 11350938 20068231 12681450 10417333 12763138 9872331 18988627 11780390 18491316 18669648 11404481 10521505 18691976 19723038 20058876 14551213 10446219
MTOR NRF1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MTOR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 29228628 10660304 22408571 12796477 16740698 18691976 26573296 15522880 27384580 26775702 24423131 26241748 23055980
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
MYC STAT6 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
PPARG NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
NCOR1 SMAD3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
PPARG NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
SIRT1 NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22395773 15175761 16713569
NCOR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15175761 11877444 15604093 16127449 11903058 22078880 23703729 9121466 21775429 17468099
NCOR1 RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18391971 9694793
SMAD4 NCOR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
SMAD3 NCOR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
NFKB1 NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15811852 10777532 12150997 16846590 16382138 15494311
RELA NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10777532 14982881 12589049 16382138
RBPJ NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 11509665 23331499 18391971 9694793 10713164 21475249 11404076
NCOR2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 15175761 16219912 20364085 15604093 17704298 17312272 23703729 9121466 19147680
PRKACA NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
NFKB1 XIAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17435549 21725609 23178297 23572150
NFKB1 NFKBIA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 1829648 21725609 23178297 23572150 8096091
NFKB1 TNFAIP3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 1332946 21725609 23178297 23572150
NR3C1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8639160 17016446
RBPJ NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14570916 11591772
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15041463 18223231 14739605 16157589 18978816 18761050 15756023 18566231 16453001
NFKB1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9266823 20669087 12471036 17673602 10827178 16210649 12466023 15517885 12622742 18294142 19618291 12067569 15655349 17556653 9988750 18973191 14988266 12871860 20103608 15555528 11082190 15234907 22001128 16820889 19766095 15997464 12349897 15387324 15368354 18057724 15547942 16624933 17767925
NFKB1 NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17876798 15499023 17709515 7775482 11744993 10454561 11060311 12885753 9250151
NR3C1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 8290595 16380507 7823959
PRKACA NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19531803 12947093 17959673 15642694 15197457
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
NFKB1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 25609649 7862124 1340770 16210649 16970925 21719482 9738011 9865693 10497169 8657102 9572494 9315679 21988832 8887676 10329681 1829648 14743216 17003112 11313474 20558726 26496610 7867065 7891711 10837071 7831327 15836773 26186194 11571291 15214841 17561400 16846590 9566883 8096091 15371334 7479976 11020244 9426183 16493424 15145317 8631829 20237821 20980497 16513645 9597130 7479848 7739549 7628694 10655476
NR3C1 NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11694573 12361720 7569975 15879558
RELA NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18204072 17876798 24083678 15499023 25759022 23422506 12859951 7775482 11744993 22723832 23450368 11060311 12885753 18981184 9250151
SIRT1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19408108 15152190
RELA NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 134.0 1.0 Omnipath 17145710 15657065 11801607 25609694 15226358 17003112 9057089 26496610 19219072 23850221 7831327 12927781 16683270 17301240 17561400 9566883 10391945 8887633 16209943 21719482 10066434 8657102 10581242 29734393 21988832 12419806 14743216 16105840 15671248 9751059 9990853 25759022 10498867 8246997 7878004 11020244 9426183 15845455 26476452 23563313 16951195 25520503 9694722 11287411 10329681 15799966 17612295 24457201 10085161 10837071 10969074 11571291 9573251 15214841 16846590 20065107 7479976 24248593 8887627 15145317 16493424 9135156 24634218 7479848 15024091 14636585 26463447 7862124 1340770 22081069 8139561 27923823 16970925 9738011 9865693 9572494 11231305 14685242 20797629 11313474 16226509 14690596 22022389 21217772 26186194 30213788 15371334 8978697 20980497 7739549 7628694
NGFR XIAP â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
PRKACA NOLC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 19651622 18669648 17322306 12167624 20068231 19664995 18212344
NR3C1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24811171 27777311 10649448 8754811 11279134
NR3C1 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17043312 7894465 2626052 2998878 15591535 3326882 2167656 11174853 8994186 2586521 8386673
NR3C1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10631313 18945810 10827178 18657608 9918831 19797430 10701683 18650268 16198345
RELA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
NR3C1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 12902338 16189514 10518526
NR3C1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
NR5A1 OXT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8713954 8025562 9607816 8108428
PPARG PDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18718916 19237535 16489446 20332343
PDX1 SLC2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19651901 22403172 23153982 9637677 17149590 11309388 8923459 9453241
STAT3 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23370526 17023536 19049975 12239103 10196143 11104795 12697721 12639901
PPARG STAT6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
PPARG STAT6 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
SMAD3 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 12457461 12524424
SMAD4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 16580992 12524424
PPARG VLDLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19706614 23811271 19861583
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
PPARG SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16670091 12777391 20406953 12777397 16096283
PPARG PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11278336 16506021 19578162 20234816 10827178 14555539 11412039 19997048 20656057
PPARG SLC2A4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18391971 17317207
PRKACA RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
SP1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12759366 16574895 16790435 9458366 9415398 12169688 10949931 12694408 11562358
PRKACA RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16769902 7476969 20215566
PRKACA TFAP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10037142
PRKACA STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 7925472 17081983 18767875 17693683 19413330 19664995 19415658 17001604 20068231 18452278 94064639 18669648 8245003 17287340 10913145 19651622 11415983 8376365 8002936 17924679 19664994 8125092 16964243 18212344
PRKACA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11931769 15833743 9150141 17959673 9660950 16135789 12628924
PRKACA SLC2A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8626492
SP1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16840740 17616668 17012241 15767339 23635401 10825178
STAT3 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24127267 14688368 21172343 20145033
SP3 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16840740 17616668 10825178 17012241
RELA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16001969 9266823 19783677 12471036 17673602 10827178 16210649 20669087 12466023 15517885 15013753 12622742 20600530 14645117 18294142 19618291 12067569 15655349 17556653 18973191 14988266 12871860 20103608 19284764 15555528 21149600 11082190 15234907 9041934 22001128 16820889 18752821 19766095 15997464 8995303 9710122 12349897 15387324 15368354 18057724 15547942 16624933 17767925
SP1 PTHLH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9030555 8063775 15889157
SMAD3 PTHLH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24330518 12628005 11473361 11590145
SP1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740727 7585542 15831516 9626663
RARA RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10929206 16613989 7969156 8388240 2164682 1316240 8001825 1650576 16832676 16782888 10629053 2153268 9108446 1318502 10629091 11839811 11497266 9184230 14528273
RARA SFTPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15044588 11274148 10070102 10617585
SOCS1 RELA â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10485906 12193701 12811837 14690596
SP1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7636984 8450395 9151857 20538607 11964305
RELA SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20617556 15152190 24064732
RELA XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15041463 18223231 14739605 16157589 18978816 18761050 15756023 18566231 16453001
SIRT1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19408108 25217963 15152190 21081649
STAT3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19345327 12057007 23335796 16713569 18448488
RELA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12055073 7933095 10671503 20861353
RPS6KA1 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 27049728 23431433 10400637
RPS6KA1 SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8413226 10318869 10753652 12171911
RPS6KA3 SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12171911 10753652 8413226 17570479 10318869
SP1 SERPINA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 8557630 11967987 9545340 11481261 19758310
SP3 SFTPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9006959 19096034 10710519
SP1 SFTPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9006959 19096034 10710519 20418387
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SPP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SPP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SPP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
SMAD4 SPP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SPP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SPP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMARCB1 SMARCA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 18414052 23540691 20506188 8895581 31759698
SMARCA4 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 12917342 23540691 9891079 28420882
SOCS1 STAT6 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 10485906 12193701 12223527 12811837 21469115 23124025
STAT6 SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21828071 18342537 15199062 17093501
STAT3 SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18843197 14630083 16432158 20003295 20357037 10809230
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24240095 11126367 17689681
SP1 TGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15533438 1501890 7936640 10828826
SP1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12706891 22734486 10446912 7478579
STAT3 STAT5B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
STAT3 ZFP36 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19542371 21606497 22865915
TRIM28 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18381204 18037959
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
ERCC6 STMN1 â—¼   KO_DOWN_REGULATES ✅ - -1.63 1.62 PKG 28854368
ERCC6 SPP1 â—¼   KO_UP_REGULATES ✅ + 2.77 2.77 PKG 28854368