Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SYNGR3 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1708774 7537266
FOXA1 AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14521963 10455192
PRKACA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAV1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GTF2B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTCF APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP F12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AR APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16987234
TFAP4 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8541835 1380960
KAT5 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10364196 5211544
AR YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19996220 8009645
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
MYB AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12096342 18945670
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
AR KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8423674 24172884
AR CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24218937 20610535
AR NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887629 20610535
PRDX1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17909037 19737972
HRAS CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621645 5220985
RASA1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731661 15504032
MYB CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10542314 15195136
CEBPB GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16418324 11012671
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
CEBPG PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9774647 8626491
CREB1 TAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7615553 7906413
CTCF NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21111075
SUMO1 CTCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19029252
GADD45A DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DYNC1H1 NF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8416976 23583712
TP53 DYNC1H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9781666 9627114
NF1 EFS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PRKACA ETS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22354960
ETS2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8649821 10510472
HNF4A F12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19786295 9794469
VCP FAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18711132 0805371105
VCP FAF2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FAF2 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
GTF2A1 FOXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17495528 14675539
FOXA1 NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8495744
SMARCA4 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
HRAS GTF2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GTF2F1 GTF2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218897 16878124
JUN GTF2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23176534 12665576
USH1G HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RASA1 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221569 9219684
TP53 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
IRF8 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16484229
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
PML JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671405 10620019
SPRED1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
LZTR1 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 31337872 30442762
MYB LCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7970721
SPI1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9292515 12027437
MYOD1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 17043109
NOLC1 NF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SDC2 NF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11356864 5214025
NF1 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
NF1 NRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 2116237 2121370
SUMO1 NKX2-5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18579533
NOLC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19541936
VCP NSFL1C â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
NSFL1C VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TP53 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
TP53 SCN3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
SPRED1 SDC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
SP3 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24219545 10446912
SPRED1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
TP53 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11420669 21187340
SUMO1 UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17698038
TP53 WRAP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19250907 21924287
TP53 TWIST1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18504427 20689556
VCP TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
1433F ATG9A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RASN RASA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24412244 34407391
CS075 NF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
F174A NF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79B ADCY3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79B NF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EPHA1 NF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SCN3B NF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
P4HA3 NF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VSIG1 NF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TN13B NF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
1433F NF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14741381 28514442 33961781
CAH14 NF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
5HT6R NF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27791021 23027611
FAF2 ATG9A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FAF2 CAV1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CEBPG JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23661758
AR FOXA1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
JUN PML â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
RASN LZTR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31337872 30442766 30194290 30639242 30442762
NF1 RASN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30194290 7499408
TAF1 JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11316804 16713569
SPI1 JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9681824 12091339
RPRD1B POLR2A â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
KRAS LZTR1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
MARK2 YWHAH â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
NOLC1 CEBPB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8972203 9553145
SUMO1 CEBPB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20194620 18820298
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
LCK NF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 34079125
TIRAP TRAF6 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
GTF2A1 TAF1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
IRF8 SPI1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
RASH LZTR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31337872 30481304 30442766 30194290 30639242 30442762
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AR STUB1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTF2A1 POLR2A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HRAS NF1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
SUMO1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
NF1 SPRE1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27313208 26635368
CEBPB CEBPG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20102225 12177065
MYB PML â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20802522 15194430
PML TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
NR3C1 SMARCA4 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CAV1 PTRF â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
GTF2A1 GTF2F1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PML JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10620019 16916642 9671405 15626733
JUN MYOD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 1310896 16713569 8380166
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
SP3 RRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19011236
MARK2 1433F â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 19615732 16959763 14676191 28514442 19553522 17979178 32707033
CEBPB AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1377818 7518671 7549116
HNF4A AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9792724 15144905
CTCF APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11706010 10582586 9407128
FOXA1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24875621 18178153
AR GTF2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12648523 9238003
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
AR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24119295 21796528 17932034
CDK10 ETS2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24218572 18242510 11313931
CEBPG NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2023930 1718972 11145742
CREB1 NOLC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21266110
CREB1 NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10435592 11175282
CREB1 SMARCA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16675956 20864035
CTCF SUZ12 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21536749 33196849 18662993
SPI1 CTSK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19288495 15304486
ETS2 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15637148 17326832 17975022
GADD45A TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR3C1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17978169 24399729
HRAS SDC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15752734 16997272 32196115
IRF8 NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17200120 15371411
JUN NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 7823959 8733011
SP3 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19197985 19011236 19994725
NR3C1 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16888650
MYB SP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16024108 18342022
TRAF6 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18093978
SPI1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16263717
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
SMARCA4 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 10688647 9590696
NR3C1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 8878484 9528750
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
SUMO1 NR5A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15192092 15192080 21467194
NR5A1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8825555 12697703 12697699
SUMO1 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15017387 15561718 28851805 16501610 19217413 22155184 22875967 24654937 31879127 21779164 20188669 9885291 9452416 17081986 21098080 22406621 18625722 21305000 17344210 17027752 11160742 19380586 23604351 23830076 17081985 9427741 11080164 16189514 23028697 21057547 19015637 20972456 8806687 20826694 24190887 25497731 17036045 11948183 9756909 18474224
TP53 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14992722 18056437 14715247
SP3 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9415398 11578973 11562358
SUMO1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18093978
TP53 TYMS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21351099 9260894
GTF2A1 GTF2E1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
YWHAH MARK2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 19553522 8009002 0803887
TP53 SDC2 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
CEBPB MYB â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
SUMO1 JUN â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 11867732 15469925 10788439
JUN JUNB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 25609649 28514442 33961781
GTF2A1 GTF2B â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
GTF2B GTF2E1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
RASH NF1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 8628317 30194290 30655611 30639242 26635368
VCP NSFL1C â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 20414249 7903886
GTF2F1 TAF1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
POLR2A SMARCA4 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
POLR2A RPRD1B â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
RASH RASA1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11389730 9219684 7628625 2833817 34407391 8663024 16713569 26721396
FAF2 VCP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
GTF2E1 POLR2A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HRAS RASA1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
GTF2E1 GTF2F1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PML SUMO1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DCTN1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
GTF2F1 POLR2A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GTF2B GTF2F1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
GTF2B POLR2A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NSFL1C VCP â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
TP53 AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11572852 14522900 11798803 11891535 18212064 15743813 16203738 18573881 15657445 9891062
JUN APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8063812 11677255 8015372
KAT5 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21832049 12032152 16223726 14699153 15331662 15044485
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
KAT5 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11591700 10364196 19150978 11994312 16713569
FOXA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23260764 22722839 16713569 12750453
AR JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11577103 11518798 9211894 8798722 16713569 9591784 17721441
AR NR5A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 11518799
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
KAT5 BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TP53 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10684646 20610713 17014845 11076533
LCK CD79B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9531288 8077654
CDK10 ETS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18242510 24218572 26871468 11313931
CEBPB KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11500490 18444174 16107878 10318842
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
NR3C1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25202013 9817600 9428795 11279134
CREB1 PRKACA â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 19244110 12150772 12082174 2573431 9733829 17908236 15879576
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
PRKACA CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11175347 12356771 15733869 11160957 21902831 2885756 2875459 7958915 9829964 12235136 12763014 9687510 8887554 15568017 11698596 8688081 9528766 11018520 11969286 11909979 8336722
NR3C1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20203101 16713569 8449898 7621901
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
TP53 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10749144 22801474 11221850 15031557 22262183 10321740 17700520 11420680 10094833 23114628 8892753 23948959 9405685 21394211 9931282 10435630 12007564 15721278 17440969 23576563 9566896 9233781 21836608 21245169 15186775 17063488 9154806 10327059 9191059 17344317 9519881 20797428 18350249 7624148 10566557 17084916 16714289 20840860 15735726 12806965 18225552 16581545
TP53 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16990795 15603758 14627995
TAF1 GTF2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17081983 11278496 18452278
TAF1 GTF2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 8625415 7590250 9660973 10428810
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
HNF4A SHBG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9852068 17992261 22210320 19786070
HRAS YWHAB â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
HRAS YWHAB â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
TP53 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21552926 9662334 11127813 21552928
RASA1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 10769036 11389730 23331499 18829532 7628625 9219684 10592173 8663024 16713569 26721396 8360177 8537347 1904555 10394594 2833817
NF1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8628317 19777070 26635368 24431436 19718661
SPI1 IRF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10570299 9593745 10734131 17386941 11483597 17200120
NR3C1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20499359 8639160 2169353 9731701
JUN MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2167198 19723510 1313772 8120060 8264634 1310896
JUN SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17283046 10411939 9178763 9988737
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
JUN SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12393465 10411939 12091339
KAT5 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
PML KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19150978
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
KRAS YWHAB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12068308 23352452 25907612 15035987
TP53 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11514734 18555006 10953306 14741382 19107228 20124454 8274455 16061648 10448271
LCK STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 25885255 34021045 12060651 9813040 12456798 21716071 12970160 10825200 11641791 9573010 31697835 11046040 18250158 22177802 22442148 29228564 11254359 19923221 12879454 14522994 20667852
LCK RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 11389730 1850098
TP53 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21611785 11713584 10365096 15217513 16258956 14675138
MYB NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16263717 15044598 22516378
NDUFB6 NDUFC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
PRKACA NOLC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 19651622 18669648 17322306 12167624 20068231 19664995 18212344
SUMO1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 12193561 12144530
NRAS YWHAB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12068308 23352452 25907612 15035987
SUMO1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22875967 9756909 25497731 17036045 21057547 18931695 19217413 8806687 16189514 17081985 11080164 11948183 9885291 19380586 17344210
SUMO1 SP3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15494207 12419227 25114211 18617891 18374648 12356736 15247228 16781829
TAF1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 28673515 15053879 20124405 16713569 29556568 24289924
TIRAP TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15247281 21873236 19592497 24084649
WRAP53 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19571673 19250907 19918835
TP53 HADHB â—¼   KO_UP_REGULATES ✅ + 1.23 1.23 PKG 28854368