Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PARP1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP1CB IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NR1H3 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11741944 16461908
E2F8 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10498616 20080631
TCF19 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
LZTR1 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 31337872 30442762
NF1 NRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 2116237 2121370
SREBF2 SND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29296233
UBE2O LZTR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KPRB LZTR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IF4A3 LZTR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KBTB4 LZTR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AIFM3 LZTR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NUAK2 LZTR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RIT1 RIT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NCK2 LZTR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NUD12 LZTR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RIT2 LZTR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PTN9 LZTR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27432908 33961781 27880917
MED7 MED16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
LZTR1 RIT2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CUL3 LZTR1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30442766 30872527 21145461 30442762 30481304
SHOC2 RASN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9674433 10783161
KRAS SHOC2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
POLR2E RUVBL1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
SHOC2 RAF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10783161 26519477 25022756
RIT1 LZTR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 30872527 33961781
RASN LZTR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31337872 30442766 30194290 30639242 30442762
NF1 RASN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30194290 7499408
KRAS LZTR1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
GABARAPL2 LZTR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
CUL3 KBTB4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 33130828 33417871 21145461
RASH LZTR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31337872 30639242 30442766 30194290 30442762 30481304
RASK LZTR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31337872 30442766 30872527 34079125 30194290 30442762
NRAS RAF1 â—¼   RELOCALIZATION ✅ + 0.87 0.87 Signor 21779497
HRAS NF1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
IKBKG TNF â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
STAT1 MED16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
MYBL2 MAP1LC3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SHOC2 RASK â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 9674433 10783161 34079125
NRAS RAF1 â—¼   PROXIMITY ✅ 0.93 0.93 mint 30194290
MED7 POLR2E â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
NRAS RAF1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
HRAS SHOC2 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
MED7 POLR2B â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
RASH NF1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 30655611 8628317 26635368 30194290 30639242
SHOC2 RASH â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10783161 30865892 9674433 16301319
POLR1B POLR2E â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
KRAS RAF1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HRAS RAF1 â—¼   PROXIMITY ✅ 0.98 0.98 mint 18273062 6540139
RAF1 HRAS â—¼   PROXIMITY ✅ 0.98 0.98 mint 18273062 6540139
RASN RAF1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 10882715 32296183 31980649 18641128 21478863 7766599 9488663 8876196 30194290 20080631 30639242
RASH RAF1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 18073111 19063885 8332187 15031288 14724584 16301319 9523700 25684575 22605333 20080631 9261098 10369681 8911690 10887184 10545207 7862125 9154803 16214894 28205554 16573649 12379659 8035810 16803888 8628317 7969158 10783161 26721396 20133694 22169110 19696784 15664191 14654780 16916524 8530446 30481304 30639242 8332195 10882715 9144171 28628118 10922060 7730360 15688026 8670882 19222999 9099670 24929361 20178605 9150145 12620389 18273062 30194290
RAF1 RASK â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 23153539 31980649 10958680 25852190 27684187 20080631 15192046 19029954 28205554 9564038 10783161 26721396 34526658 20802526 10882715 28628118 16041367 16093354 8307946 34079125 30194290 9446616
TNF IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
TNF IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
IKBKG STAT1 â—¼   DOWN_REGULATES ✅ - 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
STAT1 TNF â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
RAF1 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
HRAS RAF1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RAF1 HRAS â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 HRAS â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 HRAS â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
KRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 10958680 12750173 9516156 12932319 9665134 10783161 8805624 1386920 1639773 8340422 8601312 19595761 23331499 16041367 21071413 8332195 9446616 10882715 25852190 10531446 1996324 19029954 8503013 16093354 19541618 23153539 16293107 1708096 19933846 26721396 11136732 10205168 20802526 31980649 7760835 18775988 8307946 12917261 11134016 20080631 8180183 1990291
HRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 147.0 1.0 Omnipath 17145710 18273062 9523700 1639773 8601312 19595761 20133694 11032808 9154803 10882715 14654780 1996324 19222999 16301319 11948414 8530446 7969158 11313862 9150145 20080631 1990291 12750173 15031288 12932319 9665134 8805624 8340422 1386920 23331499 16916524 16041367 23180781 18988627 20178605 15688026 15664191 22169110 11733498 7862125 8180183 19063885 12391160 9144171 8035810 9020159 14724584 19696784 21779497 9261098 12173045 12620389 8628317 19914712 1708096 19933846 26721396 7730360 10205168 8332187 16803888 18775988 12917261 9099670 10545207 25684575 8670882 10783161 12379659 10887184 17569879 21071413 8332195 7523381 10531446 24929361 8503013 16093354 19541618 10369681 8911690 18073111 11136732 10922060 7760835 11134016
NRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 9867809 12750173 12932319 9001246 9665134 8805624 1386920 1639773 8340422 8601312 19595761 23331499 21071413 8332195 10531446 10882715 7811320 1996324 18988627 21779497 8636091 8503013 7766599 16093354 19541618 8180183 1708096 19933846 32296183 9525741 8876196 11136732 10205168 21478863 7760835 18775988 12917261 11134016 18641128 20080631 9488663 1990291
NF1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8628317 19777070 26635368 24431436 19718661
POLR2B POLR2E â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SHOC2 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17496910 23331499 19541618 19565474 21071413 11023813 9674433 18988627 10783161 19289794 11226259