Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F8 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18202719
E2F8 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16179649 18319725
E2F7 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14633988 18319725
E2F8 GSN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F7 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14633988 18319725
FHL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TTC33 DNALI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TTC33 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16179649 18319725
E2F8 GRIN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 DNALI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 ADRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16179649 18319725
E2F8 PEX26 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16179649 18319725
HTT DNALI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DNALI1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CASP6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
CASP6 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ADRB2 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
E2F8 TTC33 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
E2F8 MEOX2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
CCNA2 E2F1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
E2F1 CCNA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8458319 7969176 12501191 35140242 9724724
E2F1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20639906 16835303
E2F1 APAF1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11389439 11559530 11591730 15279786 17218262 17303408 17660363 18590585 7575488
E2F1 APAF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12766778 18524851 18951482 17600109 18093951 15972851 18056406 12149244 11389439
E2F1 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11559530 12149244 18319725 11591730 11389439
E2F1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7623816 11264255 9178900 20580656 14681231 10594784 24335704
E2F1 CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 21653699 19564413 20220142 23518498 8668155 7623816 1059478 14618416 20410059 12565705 17471231 23543735 10594784 24335704 22185819 21454377 11526499 10504464 8618861 8649818
CCNA2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15840440 16135794 9736735 15133492 15558010 15123636 9556498 12501191 16213134 11980909 16123593
CCNE1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7575488 18590585 18687693 9315635 17303408 17660363 12006580 11420722 15279786
E2F1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15510213 7575488 18590585 17303408 18319725 17660363 15279786
E2F7 E2F8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16179649 18202719 18319725