Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SNCA ELL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ELL2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ELL2 PSEN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 SCAMP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SCAMP1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF1 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TP53 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PRKAB2 TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
CDS2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CDS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SATB1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000296 20126258
CASP6 SATB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11463840
H3-5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 H3-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NUP54 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TENT5B HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TENT5B CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TIGAR CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 FGF21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATF4 FGF21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22233381
VIM CIAO2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CIAO2B CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 JMJD7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAL2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APOA4 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 LGALS9C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
XIAP NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TRAF1 NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NTAQ1 XIAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CASP6 MAOB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LHX5 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LHX5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LHX5 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RUSC1-AS1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RUSC1-AS1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LINC00518 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LINC00518 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PAAT CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CIART CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JPT1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AKR1C8 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYBPHL CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LPAL2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 C12ORF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 EEF1DP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ACTL7B CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AK8 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 ALOX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17018618
ANKEF1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRYAB ANXA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ANXA4 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APAF1 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 5214497 11550094
EIF4G2 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11943866
XIAP APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11230124 12181739
CASP6 APOBEC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NGF APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NUCB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDKN2C APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP BIRC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP SERPINA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP NGF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP8 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10409650 10911620
ASCL4 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VIM ASCL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ASCL4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATF4 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATF4 XIAP â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 23850759 26587781
ATF4 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19726676 22952236
ATG10 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATG10 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATG16L1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAAT CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BCHE CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF4G2 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14960583
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
BIRC2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17145710 12887920
TP53 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16917513
HTT BIRC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP9 BIRC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11024045 5213055
SNCA BIRC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19120021
C1D CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
C1D HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
C3ORF36 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 C4ORF33 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAPN2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 CASP10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14688482
TP53 CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14688482
TP53 CASP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21859926 16177095
CASP2 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11399776
HTT CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRYAB CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18669646 0712034105
FOXO1 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19050291 15565601
CASP6 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
CASP3 NUCB2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
HTT CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16777606 10770929
CASP3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9500443
CASP3 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18362891
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
CASP3 PTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12004072
PPP1R11 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JADE3 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RING1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POLA2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RELA CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HAUS8 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHMP7 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRY4 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SHCBP1L CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGM5 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PCYT2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2A CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LONRF2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LIPT1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PITPNA CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHD3 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPARA CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SF3B3 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKAG1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LOXL4 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WDR77 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53BP1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PITPNB CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPATS1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRCT1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LRRC56 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF3I CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLIN3 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGM1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SH3GLB2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WBP1L CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TCAP CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PTGDS CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ODF3L2 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KRT222 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DPYSL5 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRYBB3 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POLR2I CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBWD3 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DLX3 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGD5 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CITED1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CYBRD1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RBBP4 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS4X CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RHEB CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SDF4 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHF23 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZBTB14 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNW1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FAM9A CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZNF597 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL3 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WNT7A CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MRI1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPATA12 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YIF1A CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 TEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 CDC23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 PER1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 NUP43 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 GNB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 TUBB2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 EML1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 TRIM23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 POLR1D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 NAA60 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 RNF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 NUP37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 SNF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 SMG6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 SERPINA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 CCNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 EIF3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 COA7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 PTPN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 SPSB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 KCTD17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 DCAF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NUCB2 CASP6 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
PARP10 CASP6 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 8408758 23305266
LMNA CASP6 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 8663580 8655646
CASP6 NUCB1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
CASP6 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
XIAP CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9545235 15200957
TP73 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19788416
XIAP CASP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547707 9525868
CASP7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NUCB2 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
CASP9 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
RB1 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15735701 11420704
VIM CASP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHD3 CASP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PARP10 CASP8 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 8408758 23305266
CASP8 NUCB2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
CASP8 NUCB1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 6175494 18154733
CASP8 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18362891
XIAP CASP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242052 5213680
FOXO1 CASP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19050291 20200974
XIAP CASP9 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CBWD3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CCNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COPS6 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
HTT CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CHD3 CRCT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
COPS6 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
VIM CRCT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CTNNB1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22552774 12750294
DCAF7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HIPK2 DCAF7 â—¼   COLOCALIZATION 2.0 0.8 intact 20940704 8084776
SNCA DLX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT DLX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DPYSL5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F8 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF3A EIF4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 17353931
EIF3I HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC EIF4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18593934
MYC EIF4G1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18593934
EIF4G2 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11943866
FAM9A LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FAM9A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 HIPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217735 15896780
TAB1 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 10391247 15082531
LONRF2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNW1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPATA12 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LNX1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TEN1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPARA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KCTD17 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SH3GLB2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SF3B3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT YIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PTGDS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT KRT18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TFAP2A HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11483245
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
VIM IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC IKBKG â—¼   COLOCALIZATION 2.0 0.8 intact 20970423 8045055
RNF31 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24469399 21455180
LNX1 KCTD17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRT18 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ZNF597 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS4X LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ODF3L2 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LMNB2 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RB1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
LMNB1 LMNA â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TRAF1 LNX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
LNX1 TRIM23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LNX1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LNX1 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
NGFR STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TCAP PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PAK1 SPSB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POLA2 TEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
RELA PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10542237 16189514
SP1 PPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19583808
TP53 PRKAG1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
PSEN2 PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
SP1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10446206
RB1 TP53BP1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RB1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10850422 7732011
RELA TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910340 8524315
TAB1 RNF31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16260783 16953224
STUB1 SERPINA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF1 SH3GLB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
SNCA VIM â—¼   COLOCALIZATION 2.0 0.8 intact 16678164 5218597
SP1 XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17121920
SP1 TGM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10886517 21248772
VIM SPSB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
XIAP TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
VIM TCAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18980971 16636674
VIM TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF4G1 RPS4X â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EIF4A1 RPS4X â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
TRAF1 RNF31 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25996949 27893701 21903422
NUP37 NUP43 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
TP53 UBE2A â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CRYAB SNCA â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
BIRC3 DCAF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30948266 23524849
XIAP CASP3 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 9525868 6547707
DCAF7 RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27705803
MYC EIF3I â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC PTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
EIF3F EIF4A1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
EIF3F RPS4X â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
MAF ATF4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
BIRC2 RNF31 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24726327 27545878 30561431 23524849
CRYAB CDC23 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MYC LMNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
SNW1 MYC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30415952 29467282 19818711
BIRC5 XIAP â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CASP6 SATB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11463840 18408014
SNW1 LMNA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32814053 30419336 20467437
LMNA RBBP4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25948554 19734887
TOP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
RNF31 IKBKG â—¼   POLYUBIQUITINATION ✅ + 0.84 0.84 Signor 24469399
CASP9 CASP3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 1067155 11242052 11230124 18723680 25241761 15941357 17437405 8900201 15507451
TP53 PIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 12397362 5215850
RBBP4 SP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12091390 16713569 12943729
EIF4G2 EIF4G3 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
BIRC2 CASP8 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
EIF4G1 EIF4G3 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
EIF3A EIF4G1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
IKBKG RELA â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 15489227
BIRC2 NTAQ1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 33961781
CASP8 BIRC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27810922 15069192 12887920 22274400
BIRC3 CASP3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17069460 9384571
CASP8 CASP3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11832478 11437602 8962078 18669646 15254227
CASP6 CASP3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25241761 8900201 18723680
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EIF3F EIF3A â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 24396066
MYC TOP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 17314511 29467282 20195357
RB1 SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EIF3I RPS4X â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
LMNB1 LMNB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
APP CRYAB â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HIPK2 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RELA SP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BIRC2 IKBKG â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PTK2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BIRC2 XIAP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
TAB1 XIAP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CASP7 BIRC3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 30948266 16339151 9384571
CASP10 CASP8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BIRC2 TRAF1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CASP7 BIRC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 9384571 15580265 19258326 16339151 11084335 16189514
XIAP BIRC5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21536684 15218035 17613533 24083380
BIRC5 CASP3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11170436 16189514 9850056
CASP8 TRAF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12887920 11181075 11098060
CTNNB1 PSEN1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
EIF3F EIF4G1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
BIRC3 CASP9 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
LMNA LMNB1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
EIF4A1 EIF4G2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MAPT STUB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
TP53 TIGAR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16839880
PPARA APOA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19433068
TP53 ANXA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21348943
MYC APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
CASP6 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10409650 10438520
RELA BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18226221
BDNF NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19908279 25354496 9775403
CASP9 BIRC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15069192 9545235 16701639 25241761 21988832 16339151
FOXO1 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19470765 15632117 22468883
CASP10 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8755496 8962078
CASP3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9348292
MAPK6 CASP6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PIN1 CASP6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CASP6 TAB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CASP6 LMNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11901153 16189514 11331782
CASP6 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10069390
CASP7 DFFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10318789
CASP8 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10069390
MYC CASP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
TP53 CDKN2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16169070 16713569
MAPK6 COPS6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TFAP2A CRYAB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21556774
EIF4A1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC EIF4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
EIF4G2 EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10394359 16467844 10944120
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
IKBKG RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15489227
SP1 KRT18 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7537848 10094831
LMNB1 LMNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21346760 32814053 25948554 11792809 31467278 34079125 19727227 24623722 30419336 21988832 22412018 26524528 26264872 29568061 16189514 29997244 30021884
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MAF MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9566892
SNW1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SP1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7559553
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
TFAP2A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9632747 8276360 7555706
MYC PER1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PTBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20010808
MYC TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
SP1 NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22609358 16135093 21123453
SP1 NGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11839795 19114034 21123453
NUAK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21317932
RELA PIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19458071 19668231 16950761
PIN1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15175157 16713569
RELA PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20054868 10542237
SNCA SDF4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EIF4A1 EIF4E â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
BIRC2 CASP9 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
IKBKG RNF31 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
RB1 RBBP4 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
EIF3A RPS4X â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
EIF3I EIF4G1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
HIPK2 MYB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 15082531 16055500
XIAP CASP3 â—¼   UBIQUITINATION ✅ - 0.94 0.94 Signor 11447297
CHD3 RBBP4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EIF4A1 EIF4G3 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EIF3A EIF4A1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
EIF3I EIF4A1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CASP9 APAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5221774 9390557
EIF4G1 EIF4A1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219000 16932749
SF3B3 SNW1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
EIF4E EIF4G3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
NUP37 NUP43 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BIRC3 TRAF1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
APP PSEN1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
EIF4E EIF4G1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CASP3 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CASP9 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CASP7 XIAP â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
APAF1 CASP9 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
PRKAB2 PRKAG1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EIF4A1 EIF4G1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EIF3F EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3A EIF3F â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3A EIF3I â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TP53 TIGAR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20961644 22782351 20729871 27803158 23591450 24859470 20935145
PPARA FGF21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19401423 24885573 24424044 20236931
SP1 MAOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15279563 19401466 14697878 20980443 11956220 11259630 15024015 12855685
SP1 ALOX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16413224 2251250 9698605 17894944 23720274 20554538 19781662 9062372 16364163 10436859
TP53 APAF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12883670 11559530 15077176 18951482 11896574 17043642 15972851 11591730 11389439
TP53 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11591730 11559530 11423996 11389439
CASP3 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12874265 21827945 11550094
APAF1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 17145710 15829969 15024710 9390557 19494828 11113115 10617566 9539746 10364241 10722681 27476169 21060833 19118655 20829884 16977332 10329646 15210107 10393175 16352606 11242052 14555243 10376594 12773388 10206961 19337385 10428850 9488720 19788417 15262985 9922454 21827945 10749135 9651578 19698783 12792650 9837928 11227497
TFAP2A APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17651731 9048735
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372
MYC ATF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333 23612979
RELA BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15050749 17673602 12687011 12714587 15756023 12010810 18566231 16453001 20103608
BIRC2 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 9990849 12042762 9384571 17069460 11382748 11106668 16189514 11084335
BIRC2 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19223549 12867425 20301198
BIRC2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 16339151 9990849 15069192 25241761 19153467 9545235 25416956 31515488 16189514 32296183 16701639 11084335
BIRC2 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16339151 9384571 16189514 11084335
RELA BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15231833 15050749 19343319 17673602 18226221 23250755 17000776 11880364 21279667 21765477 10733571 18566231 12010810 15723831 10823821 11297551 16291753
BIRC3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 16339151 21988832 9990849 15069192 25241761 9545235 16701639
BIRC3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16339151 9384571
BIRC3 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9990849 12042762 9384571 17069460
CTNNB1 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19778454 17005722 19662654 11517919 16288908
TP53 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 19363521 19470765 19067706 17124180 11714700 16432013 18698017 21443519 12235242 20236666 22266808 16595680 15361831 23838170 17916908 15087401 15377848 19018856 19439469 22503977 17699779 11965534 15657147 18022393 18027854
RELA BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17553314 20126979 14739605
SP1 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17350596 17876054 21131823 18175117 20660371 22334592 22734486 21433308 22773958 21093004 19120021 17124180
MYC BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17170079 19287963 20508797 19602047
TP53 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19211844 11965534 11714700
BIRC5 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 9384571 11024045 9850056 10587640 16189514 16540654
BIRC5 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9384571 11024045 9850056 16189514 11170436
BIRC5 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 11069302 25241761 11024045 16189514 12773388 10329646 15210107
BIRC5 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17613533 15218035
XIAP CAPN2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11583623 12815069 12835328 21887410 23242420
CASP8 CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 22864571 17159907 17145710 12887920 11832478 11717445 21737330 15280356 12198154 3031469 15659383 170210 8962078 22421964
CASP10 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11717445 8755496 9765224
CASP3 CASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9261102 9922454
CASP2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15262979 16193064
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
CASP8 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15755874 17179148 9501089 9950028 18669646 23308069 10988287 18458084 16964285 9885230 9765224 11437602 15014070 21295084 8962078 9208847
XIAP CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 23074197 16543147 22072751 12624662 18521960 22815893 11157976 15650747 15200957 11927604 11230124 9384571 16869888 9545235 23979166 18723680 16189514 11359776 15507451 9230442 19273858 26186194 10508158 25241761 12529384 19559631 11257230 12874265 9525868 17291493 11583623 11257232 17069460 12181739 10548111 11447297 15014070 19698783
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
CASP3 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25241761 17899380 8900201 9922454 18723680
CASP3 KRT18 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9298992 11356849 16189514 12235123
CASP3 DFFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11406587 25241761 12655299 18723680 9786842 9422513 9422506 16189514 9108473 11752060
CASP3 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10822366 11420704 9092486
CASP3 EIF4G3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10611228 10672017
CASP3 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10069390 16189514
CASP3 EIF4G2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10672017 11175261 10371215 10611228
CASP3 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10224094 9463408
CASP3 EIF4G1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10611228 9819442
CASP3 PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10069390 9219695 9990034
CASP3 NUMA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9463409 17401638
CASP3 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11423904 10469173 11514563
CASP3 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12888622 16606369 22535953 11162250
TP53 CASP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19897582 16391794 18064040 16518869 12089322 24070868
CASP9 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14686614 9651578 16521476 12097334
NUAK1 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 22483120 24974292 22433863 25343534 15273717 27889207
CASP8 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18329793 12232792 9727491
TP53 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18431400 12089322
CASP6 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19788416 16601678
CASP6 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11423904 10469173 11514563
CASP6 LMNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 8710882 8900201 11058599 8663580 8978814 11953316
CASP6 NUMA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9463409 17401638
CASP6 PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10069390 9219695 9990034
CASP7 CASP9 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 16916640 9922454 11752425 11701129 12824163
CASP9 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17899380 9922454 16352606 9598997 9651578
XIAP CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 11447297 11257231 18521960 31467278 15200957 9384571 9545235 14512414 23979166 16189514 11359776 9230442 10508158 19559631 11257230 9525868 11583623 15580265 11257232 23074197 19698783
CASP8 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18073771 9545235 10872455 18329793 9727491 9463409
CASP7 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10069390 16189514
CASP7 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11423904 10469173 11514563
CASP7 PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10069390 9219695 9990034
FOXO1 CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20200974 19050291 15632117 15565601
MYC CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15367674 12695333
CASP8 TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17145710 12887920 11098060 11181075 12709429
CASP8 PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10069390 9219695 9990034
XIAP CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 62.0 1.0 Omnipath 15069192 15280366 25416956 18022362 11157976 31467278 15200957 11927604 11230124 12042762 16322207 9545235 11801603 25502805 14512414 16189514 15300255 15507451 10508158 25241761 27107012 14523016 17179183 16352606 11242052 32296183 16701639 17291493 12620238 15749826 12181739 11390657 29997244 31515488 23074197 19698783
CASP9 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19118655 11423904 10469173 11514563
SP1 CDKN2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18642058 15107822 22504641 12077144
TP53 CRYAB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19343786 24859470 19777343 21556774 19799611
MAF CRYAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11069887 10603348
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
PIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 11533658
PSEN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 17145710 11168528 16126725 11226248 2195779 11161700 12070348 9738936 10037471 18070361 9632714 10092585 9223106 12297048 16306047 10341227 9852041
PAK1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 28007610 28423670 23543898 25639486 26547035 22369945 23162742 25472536 21822311 25225063 27713506 27910850
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
CTNNB1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17254970 15905404
MYC DFFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 18500556
EIF3I EIF3A â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 14519125 33961781 24981860 26344197 17353931 22939629 8995409 18599441 26186194 28514442
MYC EIF4E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18593934 15094771 8756633 12695333 24814906 14519204 22456335 16112647
EIF4G1 EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 8521827 22509910 17689282 23665581 22586265 16648488 16467844 9372926 16541103 15361857 16720573 9418880 16281055 18955708 12071973 21191102 26186194 10753870 15153109 10600798 7651417 20212144
MYC EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18593934 16915296
PPARA FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16985262 18391971
PIN1 HIPK2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12851404 23000554 11780126 11511362 11740489 24145406
TP53 HIPK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16343438 19642869 18809579 18483253 19828042 21248071 18336191 11925430 11740489 11532197 17658469
HIPK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19828042 25210797 20508833 22545114 23814485 19731416 11740489 20171273 11875057 16212962 16729035 23700162 23945296 24101931 27308326 16713569 23536002 28107201 27901482 27019364 19714248 22011578 27308327 15896780 16601678 23316480 24145406 28122345 21192925 17906639 25313037 27689990 20849851 21258400 17203463 19128456 17349959 25364713 11925430 20418953 24829283 22935610 21855806 28893313 23717325 11780126 19946469 21057547 23293771 27787517 26942128 15865933 17210684 17332358 22110707 22889244 23091802 24211575
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
RELA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RNF31 IKBKG â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
TRAF1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
IKBKG RELA â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
TRAF1 IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
PAK1 MAPK6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21372320 21177870 18720373 21317288 18248330 17161475
PIN1 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10391244 16713569 11090625
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
MYC PIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC PIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
ZBTB14 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10936031 10080939 9092617 9618270 8367294
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
MYC PSEN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12695333 18414489
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
PIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26655473 15048125 30723410 23716601
NGF NGFR â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF XIAP â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10764727 11729324 16893414 2172988 1372492 24224055 14985763 22227462 11114882 15258592 14699954 3037029 1714587 9775403
NGFR XIAP â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
PAK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 14722118 11895474 17081983 16565220 26369929 28390425 27457922 11420699 15713670 15766329 7983050 12458200 12761892 26956613 16964243 28096473 15345747
PIN1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12397362 12388558 17906639 12397361 21741598 16713569 24982848 21900206
TP53 PTK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24809783 20515733 21355845 21071137 21269258 18493017 17999388 17725966
TP53 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18431400 25241761 15855171 18206965 19857493
SP1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18801742 12760745 8007947 1588949 17384411 21465530 15618023 7896792
TFAP2A RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11835395 9632747 21850486 9776742
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
SP1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7636984 8450395 9151857 20538607 11964305
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
RELA TRAF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19343319 17673602 14991743 19383900 17018379 9733827 9733516 10823821 11297551
RELA XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15041463 18223231 14739605 16157589 18978816 18761050 15756023 18566231 16453001
RELA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12055073 7933095 10671503 20861353
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
SP1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17663720 22227038 3419902 10777586 12771217
XIAP TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9878061 12048196 17560374 27107012 11865055 23818254
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368