Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAB3A PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
GSK3B CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
GSK3B MAPT â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17078951 5219283
PLD1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLD1 CFL1 â—¼   COLOCALIZATION 2.0 0.8 intact 6173882 17853892
RHEB PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18550814
PSEN1 ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
APP ADAM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ADAM10 APP â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 20676056 10097139
ADAM10 CDH1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 18434311 15958533
APBA1 PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217828 16007100
CLSTN1 APBA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17332754 5219717
NCSTN APH1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18201567 6174903
APH1A APP â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
APH1A APH1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 16252010 16630834
APH1A TRAF6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
APH1A NGFR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
APH1A NGF â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
APH1B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APH1B NGFR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
APH1B NGF â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
APH1B PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12522139 12471034
APH1B TRAF6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
RNF32 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PDCD4 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CDC37 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CYP2C8 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
ST13 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN1 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
ECSIT APOE â—¼   COLOCALIZATION 2.0 0.8 intact 21163940 114280
BCL2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STXBP1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF32 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
NGF APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BCAP31 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KCNIP3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
ELK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOTCH4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TMED10 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIK3CG APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRAM1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSMC3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSENEN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ICAM5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HMGB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP NGF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP TNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP CASP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11967258 12191486
CASP8 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10409650 10911620
ATF4 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATP2A2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7834747 8692945
BAG6 DNAJB11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VDAC1 BCL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0907555106 19706527
FKBP8 BCL2 â—¼   DOWN_REGULATES ✅ - 2.0 0.8 ACSN 10409669 20139069
TCF7L2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17404573 23671559
NOTCH1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9881968 16990763
KRAS BCL2L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16483930 29311131
PSEN2 BCL2L1 â—¼   COLOCALIZATION 2.0 0.8 intact 10446169 5211736
CDKN2A BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19049976
TP53 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
CASP1 GAPDH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17959595
CASP1 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18667412
CASP6 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
TP53 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RHEB CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
HSPA5 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11943137
JUN CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18196534 17922191
RAD23A CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
NOS3 CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN1 CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PRKACA CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
CDH1 PRAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNND1 CDH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8660921 14610055
GAPDH CDK5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RNF32 CDK5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN1 CDK5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
MAPT CDK5 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17078951 5219283
PSEN1 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CIB1 PSEN2 â—¼   COLOCALIZATION 2.0 0.8 intact 5211550 10366599
CREB1 CYP51A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12145339 16123160
CREB1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16497991 16651461
CREB1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11116137
CREB1 TNF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
CREB1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10775268
CTNNB1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
GFAP CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18948405 15031118
CTNNB1 PKP4 â—¼   COLOCALIZATION 2.0 0.8 intact 5215447 12047349
PSEN1 CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10208590 11226248
CTNND1 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10208590 11226248
ECSIT CYP2C18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PGRMC1 DHCR24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NOTCH1 DLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 20351093 22363487
PSEN1 DLL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 22330899 22363130
MYOD1 DLL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15300513 10202155
PSEN1 DLL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12794186
DNAJA1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DNMT1 ENSA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
PSEN2 ECSIT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN1 ECSIT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
GCDH ECSIT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
RNF32 ECSIT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
ECSIT PSEN2 â—¼   COLOCALIZATION 2.0 0.8 intact 21163940 114280
PSEN1 EFHD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
EIF4G1 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10859165 5212678
PDCD4 EIF4G1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12054647
EMC8 EMC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PSEN1 ENSA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN1 EPB41L3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
ERBB4 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 17496910
ERN1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6542966 18369366
ETV1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12928043 12750007
ETV5 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17489097 17126306
PSEN2 FBXL12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
SKP1 FBXW7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21620836 8177582
JUN FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21460851 20638938
PRKCA GAP43 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2562806 7891109
PRKACA GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 GCDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
NOS3 GCDH â—¼   COLOCALIZATION 2.0 0.8 intact 21163940 114280
NOS3 GCDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
ZNF436 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA8 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9038169 9151685
KCNIP3 GFAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19238593 18579744
TP53 HMGB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547598 9472015
HMGB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18218727 19158276
ZNF436 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS ITGB3BP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS HSD17B12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPA8 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
JUN HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 20566634
PSMC3 HTRA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TBL3 ITSN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
UBC JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
JUN UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN MAPK9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
TCF7L2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
JUN PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20444941 7841543
JUN PSEN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
MAPK9 JUN â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19527717 7148309
PSEN1 KANK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
NOS3 KANK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PRKCZ MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18667433 17646398
MAPT ZFHX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPT TUBA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1421571 16687396
NOTCH1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12050162 10066785
NPR1 NCSTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18942891 0060257
PSENEN NCSTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18201567 6174903
NCSTN PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10993067
NGF TRAF6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
NGFR TRAF6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
TP53 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
PSEN1 NOTCH1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 22330899 22363130
NOTCH1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22330899 22363130
NPR1 PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18942891 0060257
PIK3CG PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8765021 16527821
RNF32 PRAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PRKACA PSMD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10614633 9895308
ST13 PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
RMDN3 PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
UMPS PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN2 PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
ZNF436 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22607268 20036849
UBQLN1 PSEN1 â—¼   COLOCALIZATION 2.0 0.8 intact 5213196 11076969
PSEN1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19012753 18996842
UBQLN1 PSEN2 â—¼   COLOCALIZATION 2.0 0.8 intact 5213196 11076969
PSMA4 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSMB2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSMB5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSMC2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSMC3 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RAD23A PSMD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMD2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PTGER4 ST13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
RHEB UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAMBPL1 RNF32 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
RPL38 TMCO1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 SCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
SSR4 SSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17380188 5219807
SSR4 SSR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 28218252 11964406
TP53 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14990988
TDP2 UBC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TDP2 UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
APP PSENEN â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
PSMA4 PSMA7 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PSMA7 PSMB1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
TDP2 PDCD4 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
TRAF6 GSK3B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 30711629 30806153 31594754 31754475
PSMA7 PSMA2 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 6175987 17948026
PSMA4 PSMA6 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
DNMT1 UBC â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
APBA2 CLSTN1 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CASP8 TRAF6 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CDC37 GFAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24189400 32296183
EMC1 FKBP8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 27342126
RHEB SRPRB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHEB UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOAT1 RPN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 29128334
CDH2 CTNNA1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
APOE MAPT â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
SSR3 SSR4 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
PSMA2 PSMA4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CTNNB1 CTNND1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
VDAC1 APOE â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FAF2 ECSIT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EMC1 EMC2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
FAF2 UBB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 18775313
HMGB1 GFAP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 29382328
PSMA4 PSMA2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 6175987 17948026
VDAC1 RPN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31536960 26344197 29128334
SKP1 UBB â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
PSEN1 TMBIM6 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
PSEN1 TRAF6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DDOST STT3A â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CDC37 CDK5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9150368 23455922 33961781 21163940
NCSTN PSEN2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
GSK3B CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 16293724
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
HSPB1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
GSK3B CDC37 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29568061 23455922 33961781
TRAF6 CASP8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16436380 27810922 16920630 30979779
RPN2 MLEC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 31831667 22988243
PSMA7 PSMA4 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6175987 17948026
DDOST RPN1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CASP8 BCL2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16183855 11406564
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
PSMA2 PSMA6 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
TRAF6 PSMD2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
RPN1 RPN2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PSMB5 UBB â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
PSMB5 UBC â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
STAMBPL1 UBB â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CDH2 CTNND1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
RPN2 STT3A â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PSMA2 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMA5 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMA5 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMA6 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMA7 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMA7 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMB1 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMB1 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
MAPK9 JUN â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 9405416
BCL2 BCL2L1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CASP8 CASP3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11832478 11437602 8962078 18669646 15254227
CASP6 CASP3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25241761 8900201 18723680
SKP1 UBC â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
APOE APP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CTNNB1 SKP1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BCL2 FKBP8 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
NGFR TRAF6 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
RAD23A UBQLN1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
APBA2 APBA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
APP BACE1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
NOTCH1 FBXW7 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 23022380
DNAJA2 HSPA8 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ID1 MYOD1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 JUP â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
BCL2 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
FBXW7 JUN â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
DNAJA1 HSPA8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HSPA8 MAPT â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CDH1 CTNNA1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
IRAK2 TRAF6 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
PSMD2 RAD23A â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
DNAJB11 HSPA5 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
JUN MYOD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 1310896 16713569 8380166
CDH2 JUP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CTNNB1 PSEN1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PSMC3 UBB â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
APP NCSTN â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CDKN2A TP53 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PSMA2 UBB â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PSMA6 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
DNMT1 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B CDK5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
PRKCA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19836308
STXBP1 PLD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8024366 19323535 7215275
ADAM10 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19601831 19726682 19704010
APBA1 STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9395480 15563604
APBA2 STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9395480 15563604
APH1B PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12297508
APH1B NCSTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12857757 12297508
LRP1 APOE â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 2779654 11421580 15182176 20030366
CASP6 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10409650 10438520
APP GAPDH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21832049 16713569 8473906
FKBP8 BCL2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15905180 15990872 15733859 17942410 17379601 12510191
JUN BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14623928 17262823 19335069
CTNNB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17404573 16288908 12782598
CREB1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11450946 16205321 18830594
CASP1 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10069390
CASP3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9348292
CASP6 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10069390
CASP8 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10069390
HRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
NRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
KRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
TP53 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15383401 20332115 21478913
CREB1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
ETV1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
ZNF274 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19340300
CREB1 SLC2A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23493374 15054091 23321477
KCNIP3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12198160 16189514
PRKACA CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22798526
ELK1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12928043 12750007
ELK1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10913190 19687146 11520792
TP53 FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23518350 19366810 12824889
TP53 FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31346036 12824889
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
JUN NOTCH4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23917222 21679465 17220278
RPN2 NGFR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCZ NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24379783
PRKCG NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24379783
PRKCB PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576165
PRKCG PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576165
TMED10 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 16641999
SCAF11 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10069390
TP53 TMEM33 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
FBXL12 SKP1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CDK5 MAPT â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
PSMC2 UBB â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
PSEN2 PSENEN â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CDH2 CTNNB1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CTNNA1 JUP â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
DDOST RPN2 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
PSMC3 UBC â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CTNNB1 CDH2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 36950384
MLEC RPN1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
PSMB2 UBC â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
PSMB2 UBB â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
APBA2 APP â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
PSMA4 UBB â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
PSMA4 UBC â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
PSMC2 UBC â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
SSR1 SSR3 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CDH1 CTNND1 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
EMC1 EMC8 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
DNMT1 UBB â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MLEC RPN2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
RAD23A UBB â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
HRAS PIK3CG â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
PSMD2 UBB â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
FBXW7 NOTCH1 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
STAMBPL1 UBC â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
ERN1 HSPA5 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
HMGB1 TP53 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PSMC2 RAD23A â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RPN2 STT3A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
UBC UBQLN1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
BAG2 HSPA8 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
PSMD14 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PSMD2 UBC â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
DDOST MLEC â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
RPN1 STT3A â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
PSENEN PSEN1 â—¼   CLEAVAGE ✅ + 0.96 0.96 Signor 12522139
APBA1 APP â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CTNNB1 GSK3B â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PSMD14 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
TCF7L2 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 11713475 5214798
APP PSEN1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CDH1 JUP â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
BCL2L1 TP53 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MAPT PRKACA â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
JUN MAPK9 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PSEN1 PSENEN â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
APH1A PSEN1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
APH1A PSENEN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
APH1A NCSTN â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
NCSTN PSENEN â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
PSMB1 PSMC3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DDOST STT3A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
PSMA7 PSMD2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
PSMA7 PSMC3 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
PSMB1 PSMC2 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
NCSTN PSEN1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PSMB5 PSMD2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PSMA7 PSMB5 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMB5 PSMC3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RAD23A UBC â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTNNA1 CTNNB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EMC1 EMC2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
FBXW7 SKP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA2 PSMB5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA4 PSMB5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA5 PSMB5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA5 PSMA7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA6 PSMB5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA6 PSMA7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA7 PSMB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA7 PSMC2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA7 PSMB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA7 PSMD14 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB2 PSMB5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB5 PSMD14 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB5 PSMC2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GSK3B MAPT â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DDOST RPN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMA2 PSMA7 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMA4 PSMC3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMA4 PSMA7 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMB1 PSMB5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPN1 RPN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DDOST RPN1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA2 PSMD14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA2 PSMC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA2 PSMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA4 PSMD2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA4 PSMC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA5 PSMC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA5 PSMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA5 PSMD2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMD2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMD14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB1 PSMD14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB2 PSMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB2 PSMC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC2 PSMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CTNNB1 TCF7L2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA2 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA4 PSMD14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA5 PSMD14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMB1 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC2 PSMD14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC2 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC3 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC3 PSMD14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD14 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EMC2 EMC8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMA6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMA4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMA5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA4 PSMA6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA4 PSMB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA4 PSMB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA4 PSMA5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA5 PSMB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA5 PSMA6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA5 PSMB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA6 PSMB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA6 PSMB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMB1 PSMB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMB2 PSMD14 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMB2 PSMD2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PRKCZ GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18353303 14657655 11481324
PRKACA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16543730 15845746 18691976 19836308 8524413 12054501 16039586 12147701 16522636 11035810 18669648
GSK3B NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16944320 15465828 12123574 11967263 14663202 8524413 21828089 16713569 9832503 15020233
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
GSK3B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16568235 12162494
GSK3B PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 11104755 17389597 17360711 16814287 10997338
GSK3B JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 23331499 1846781 25979842 25241761 20537194 21278055 21397588 17482134 1516134 8384355 17570479 16023596 17215518 30086763 92065884 24632621
GSK3B MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 141.0 1.0 Omnipath 19616957 22278060 25641096 9832145 19562805 12387894 24268883 9546672 31640277 21865886 19413330 28386764 28379300 1330687 28734998 19415658 15302935 17047304 7706316 27349344 29408874 9716264 9353289 21671254 24165324 12714590 20068231 12387897 17570479 16452634 25815351 21215781 16568235 16519507 8999860 17045592 9565682 27857758 11181841 14690523 22690349 27073700 21443865 10601262 7566346 10737616 15522877 12435421 17287340 9771888 29725295 15073173 17078951 19651622 1181841 15542598 9735171 12226093 11104762 21985244 20049527 28835279 27965573 20679343 20308788 9199504 18510355 10090741 11311121 2387894
GSK3B VDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16288047 23993956 29682501 18381814 25296756 21530686 22995655 26883165 19720099
GSK3B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 183.0 1.0 Omnipath 22415718 11967263 27158593 29455668 19303846 19797085 8638126 19293931 23056571 22662165 25352148 16611981 27068260 28337019 10671551 21743491 20688898 16293724 23721711 23552738 18687691 28977889 19622173 12051714 25241761 27683053 28549350 22699938 19565571 23076981 21562161 19575820 20219694 20537194 10330181 21986938 29183346 27773936 11251183 19711366 21035499 19675674 7542250 23151663 24451375 14663202 23804296 8524413 25639486 23770025 18070361 26892600 30143633 9233789 19667122 27507058 19061640 19223551 29387014 23331499 16199882 11533658 18644116 24501426 24913829 11835406 17318191 26014148 25366337 28183999 22640743 26910375 12000790 12114015 18387957 19107203 9832503 16371461 29805709 27462866 20137080 27902311 12040186 19576224 25644994 12615961 19060929 25897075 12851486 15465828 17053159 18952601 10228155 15020233 17444818 20140245 26453498 17052453 16944320 24015932 23602568 24975844 24931005 28948000 20080742 23209942 30271168 28220106 16520547 28430641 11818547 25546293 27672271 11955436 11154277 26373837 16039586 23778311 28697793 20302655 25136145 26905812 22216350 8666229 12957350 23109003 10074433 28529629 20215423 21329734 11254732 9501208 27098453 27281614 30279527 19631635 25482131 18455992 24403311 11274345
GSK3B CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16944320 11348595 11967263 14663202 8524413 20080742 19797085 12040186 16611981 10671551 16039586 12615961 15465828 17928543 24063632 10671552 15020233 19575820 17444818 20537194 17052453 9832503 18455992 16371461 11274345
PRKCA PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 1559964 11459228 9989263 11042115 12429840 17570479 10441128 12839565
STXBP1 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14744865
ADAM10 DLL1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 18676862 19601831 19704010 19726682 22006996
ADAM10 NOTCH1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 18676862 19601831 19704010 19726682 22006996
DLL1 ADAM10 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 9244301 12354787 17401372 10882063 19726682
ADAM10 NOTCH1 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 9244301 12354787 17401372 10882063 19726682
ADAM10 DLL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19601831 12794186 19726682 19704010
ADAM10 NOTCH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12651094 23331499 19726682 19704010 19601831
ADAM10 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19726682 28624438 19704010 19601831 22399336
ADAM10 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 32814053 30538620 12535668
APP APBA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12196555 12972431 11517249 9890987
NCSTN APH1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 15189355 21071413 14572442 12471034 12857757 18201567 12297508
APH1A PSENEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12522139 15322109 12740439 16189514
APH1A PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12522139 12471034 16189514 12297508
APH1A PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12471034 16189514 12297508
APOE APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9202294 10559559 10428074 10842709 17116874
APOE MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9512010 8620924 7566652 9147408
JUN APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8063812 11677255 8015372
CDK5 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 18833287 15178331 15917097 11877420 17085446 16554819 21947912 8131745 11517218 17459339 14970211 10341243 16705182 24610780 22112898 8764598 14557249 16223726 19455415 19090995 10936190 11146006 15944381
BACE1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 30538620 22801501 10677483 20418918 12901838 10531052 10931940 32814053 28923680 28869759 19251705
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
HMGB1 BAG6 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12646658 15802534 19931333 22842346 26618107 27048821 27192565
BCAP31 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9334338 17145710 12594175
BCAP31 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9334338 17145710
BCAP31 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9334338 17145710 12668660
BCL2 TMBIM6 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532 9660918
PRKCA BCL2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10677502 10679481 10871288 11323415 16492141 20027184 9115213 9738012
TP53 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17693666 8183578 10037739 16738310 18397889 19521340 18487508 21666495 16294215 21656028 22869582 19714248 10744634 8174112 17592775 11782367 19137013 20428827 18682598 11713302 11313951 20501806 9649502 24814047 15767042 24098340 11193470 10329733 21859835 22266868 10953306 19555669 23638218 14684736 19411072 20530667 24155778 8205530 20840522 9000137 15326476
BCL2L1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18835031 14980220 26186194 11583631
FKBP8 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10409669 15990872 15733859 17942410 12510191 17379601 20139069
PRKCA BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 12039060 9115213 12213578 11323415 17610064 9738012 19117992 24212628 10677502
TP53 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12667443 19555669 8205530 19007744 11313951
CASP3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10409669 9395403 20139069 11948397
BCL2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16183855 11406564
TP53 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22869582 9582400 9989972 11713584 18172861 23519249 12705879 9000137 11713302
FKBP8 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16189514 12510191 15733859
TP53 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 24814347 12667443 16151013 26556313 14963330 16713569 20837658 24474649 21900206
BCL2L1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 24814347 12667443 16151013 26556313 14963330 16713569 20837658 24474649 21900206
BCL2L1 VDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12767928 17209561 16189514 10365962 10737788
TP53 CASP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16135520 12459463 15580302 21943362 11278253
CASP1 PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10069390 9219695 9990034
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
CASP8 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15755874 17179148 9501089 9950028 18669646 23308069 10988287 18458084 16964285 9885230 9765224 11437602 15014070 21295084 8962078 9208847
CASP3 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25241761 17899380 8900201 9922454 18723680
CASP3 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10069390 16189514
CASP3 EIF4G1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10611228 9819442
CASP3 PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10069390 9219695 9990034
CASP3 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12888622 16606369 22535953 11162250
TP53 CASP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19897582 16391794 18064040 16518869 12089322 24070868
CASP8 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18329793 12232792 9727491
TP53 CASP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18431400 12089322
CASP6 PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10069390 9219695 9990034
CASP8 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18073771 9545235 10872455 18329793 9727491 9463409
CASP7 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10069390 16189514
CASP7 PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10069390 9219695 9990034
CASP8 PSEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10069390 9219695 9990034
ERBB4 CDC37 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8617201 16978839 10878805 15643424 15568014 1973074 8665853 11071886
CDH1 CDH2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH1 CDH2 â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH1 TNF â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
ID1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 23555842 16007183 17639499 17202424
PSEN1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10635315 11226248 16126725 11953314
CTNND1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 7542250 17261850 22752307 9535896 7651399 12707304 23180380 24424122 12640114 11226248 29207493 10225956 12427869 21670201 22850631 20371349 20940130 25468996 10409703 14610055 7876318 22715382 10629228 19711372 8660921 10931041
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
CDH1 CTNNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 7542250 19016843 25468996 9326449 16212417 11960376 11801604 8227214 10381631 16219695 9700170 24336504 22750944 9233779 11226248
CDH2 TNF â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18948590 20398329 21506126 20028971 12040186 12604612 21303971 20214616 17098867 11882383 22094462 8120095 21357690 17679699 17680028 12151522 17057644 21255999 18218901
TP53 CDK5 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 10604467 17591690 12064478 18490454 10500146
CDK5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 9372954 21317932 11483158 11740489 19413330 19664995 21600237 11554766 11709713 16552184 10884347 16377624 17591690 15866171 17287340 17967874 92065884 11780126 12064478 10570149 26146988 15701641 17117479 17108107 14702041
CDK5 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20213743 25177270
CDK5 STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12963086 15489225 16189514 9933594
CDK5 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 103.0 1.0 Omnipath 16697218 26944284 21945393 9614189 7592534 9832145 19562805 12387894 21848865 27641626 24268883 9546672 12071639 19413330 1330687 19415658 15302935 9353289 21671254 20508838 8282104 20068231 26998748 16568235 21215781 17045592 9565682 11181841 7566346 12435421 17287340 9771888 15843619 17078951 22761989 24367683 19651622 1181841 9735171 11104762 12226093 9199504 18510355 11311121 2387894 28785087
CDK5 HTRA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21701498 22675361
CDK5 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12056836 15917097
CDK5 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 27206849 26815200 21565170
HRAS CDKN2A â—¼   UP_REGULATES ✅ + 15.0 1.0 ACSN 10358164 12134164 12447393 14764585 16102570 17673906 20841469 24027568 24954210 7510700 7673236 8551221 9069260 9763606 9846483
ID1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 11507043 11234019 17639499 15064751 11427735 17565736 18240291 22714536 19567783 21933340 20484992 15138269 24177224 22025288
TP53 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16103197 22467867 18555006 8631601 11402335 19649205 22020338 21164364 17265068 16764954 15775976 22056554 18275833 21483786 10348346 19216023 12384561 12091906 19901969 11360201 15205322 11818069 21892281 10980602 11739748 11559812 24672805 10097151 17907153 19244234 15361884 10652576 9436028 21447739 20569441 21555589 21637567 10816133 9774662 19240179
PSMC3 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18805416 17334400 14665636 16713569
CDKN2A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15856024 15989956 9724636 19960022 12740913 17158541 12640129 19590512
PRKCA CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22855535
CREB1 PRKACA â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 19244110 12150772 12082174 2573431 9733829 17908236 15879576
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
PRKACA CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11175347 12356771 15733869 11160957 21902831 2885756 2875459 7958915 9829964 12235136 12763014 9687510 8887554 15568017 11698596 8688081 9528766 11018520 11969286 11909979 8336722
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TCF7L2 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24214913 14706452 19347947 24317174
CTNNB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20300972 19671687 16007074 9990071
JUN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17146436 18347071 16007074
PSEN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 17145710 11168528 16126725 11226248 2195779 11161700 12070348 9738936 10037471 18070361 9632714 10092585 9223106 12297048 16306047 10341227 9852041
MAPK9 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 19623618 18423204 25639486 22074626 19667122 18604449
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
CTNNB1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17145710 9488439 11713475 12446687 17143293 27902311 16569639 22014570 16724116 11955446 16442529 26350900 19202075 17050667 20126258 22056988 16306047 17914096 19443654 18391971 21670201 22155184 10080941 17283121 16230076 22304967 16630820 15684397 11713476 12861022 19304756 20492721 19816403 18772112
DLL1 NOTCH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 21685328 11006133 12482954 22353464
DLL1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 29910816 22353464
DLL1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17537801 11006133 9819428 21685328 1006133 16140393 98194281 22353464
HSPA8 DNAJA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20084477 20809635 24012426 7828728 20072699
DNMT1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21765477 24875904 23335796 22742857
TRAF6 ECSIT â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
ECSIT NDUFS7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
TRAF6 ECSIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 25371197 21525932 10465784
ELK1 PRKCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26010542 16297876
MAPK9 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9130707 20506250 8846788 8654373 20028971 17875713 16393692 26538579 11145955 11309409 8887554 26370088 8548291 15782123 8262053 19436832 12665513 12947314 11274345
ERLIN2 HRAS â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
ERLIN2 KRAS â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
ERLIN2 NRAS â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HSPA5 ERN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18624755 26551274 31226023 12637535
PRKACA ETV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 12569367 23774214 12917345 11551945 12213813
PRKACA ETV5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11682477
FBXW7 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14739463 28036276 18930588 16023596
FBXW7 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15592418 11585921
FBXW7 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11425854 11461910 20571051 23331499 20823234 17909182 25344755 32792479 11585921 16713569 17646408 27229929 15546612
RHEB FKBP8 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 12906785 17991864 18466115 19022819 19143635 23087689
RHEB FKBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18676370 18658153 17991864 19222999
GAPDH RHEB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19451232
PRKCA GFAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 9099667 7822264 12177195 2155236 2114109 12686604
PRKACA GFAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9099667 7822264 19170683 11918673 12177195 2155236 31682229 2114109 12686604
IRAK2 HMGB1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
HMGB1 TRAF6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 18070982 15247281 21220427 12140561 12138165 8837778 19592497 18347055
TNF HMGB1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10925299 11112697 11438547 11875494 12646658 12811837 1431106 14607933 14625680 15099563 15699106 16713974 17916596 18633355 19411070 20038811 20184663 20435894 21133840 21411734 21826665 22595692 22955274 23170255 23430059 23508573 23510023 23567181 23769623 24092389 24378531 26201938 8910423
TP53 HMGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9472015 23063560 11748221 16713569 11106654
HMGB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9472015 23063560 11748221 16713569 11106654
HRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
TP53 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21552926 9662334 11127813 21552928
HRAS PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9069260 9727023 17145710 10922060 11136978 21779497
HSPB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25241761 16169070 16713569 17184779
ID1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 12145280 9242638 15029197 8380166 20195544 9528857 1922066 18674781
IRAK2 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 21988832 10383454 21903422 9374458 12659850 17878161 26250868 24973222 33799071
JUN MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2167198 19723510 1313772 8120060 8264634 1310896
JUN TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 12759366 11087751 7935377 21059644 16881863 24548427 12509451 9826775 10318823 8998076 18408586 15546613 20164416 7896795 9211933 10952728 9566900 23583459 10748079 24009130 10954918 10754326 9813054 10837498 9988757 11739517 16365438 19285436 16199883 8816436 10551799 8552071 9160673 11490006 21098092 16483936 10688670 10913190 16888805 9030359 25567680 9760243
JUN NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11382920 17933457 20371606 16453281 18556800 17919072
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
JUN NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11905996 11733514 8717334 2111020
MAPK9 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 17143273 17145710 17637567 12584171 20506250 11948398 15378002 16824735 9687508 8654373 20028971 12788955 9305638 15302935 26091349 33822843 18362184 17875713 16393692 9405416 17570479 1922387 18252863 25561726 7737130 10490605 17189706 11896587 34408980 11274345 20178741 8525045 16076903 7992057 19527717 7600582 17215518 8985011 11801649 19118012 11278395 8001819 8137421 19436832 16533805 8945519 12881422 9315636 10385525 12093796 14523011 19910486 15212693 8157646 12040039 11562357
KRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
TP53 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11514734 18555006 10953306 14741382 19107228 20124454 8274455 16061648 10448271
PRKCA KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20802526 34333552 23331499 25713064 27791178 18458061 9922370 18182391 16483930
KRAS PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9727023 16189514 10542052 21779497
PRKCA LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15272003
PRKACA LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12069755 19651622 11158305
MAPK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 12356735 14665630 26158765 18778462 12969974 12861053 15254178 17135248 18669630 12384533 17363488 17698850 11283254 10706102 21454683 18931691 11551930 11397945 14612532 15064747 15963507 11175334 11423984 27147566 29234486 24657168 10581258 14517211 17353187 10673500 22030623 14527925 22728651 17525747 15629715 9393873 11447225 15671037 22285752 17245430 15140942 28673515 23871434 11078726 20041275 11896587 16731759 17121812 33514736 11861384 25431954 12810724 17967874 12955074 21832239 16818520 12756247 23798621 11526498 20009884 16713569 10202145 11850826 11896572 10710310 10570149 12959929 15269203 11583595 21148320
MAPK9 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18667537
PRKACA MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 77.0 1.0 Omnipath 9614189 9832145 19562805 12387894 9546672 19413330 1730702 7706316 9353289 20068231 16923168 21215781 8999860 9565682 11181841 10737616 7566346 12435421 17287340 9771888 19651622 9735171 11104762 12226093 16000144 8163474 26840030 6412713 9199504 10090741 11311121 2387894
PRKCA MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17570479 11025438 1335366
NCSTN PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 12603837 23331499 21071413 14572442 12471034 10993067 18201567 18988627 12032140
NGF NGFR â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10764727 11729324 16893414 2172988 1372492 24224055 14985763 22227462 11114882 15258592 14699954 3037029 1714587 9775403
PRKCA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 33539947 25814956 12384459 27191895 18622039 27106139 12574113 12869534 21797845 11729179 21757745 25020117 28833096 12644458 24612481 24379783 16527893 16527820 12952971
PRKACA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15319357 12522122 34204249 10376603 31923467 16839566 33429979 34026871 16946136 10908731 10671564 16270749 11729179 12171920 26132171 11978735 17572401 24379783 10376602 16873402
PRKCB NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24379783 24790142
NOTCH1 SKP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11585921 15546612 11461910 18094723
NOTCH1 PSEN2 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 10879540 10206645 12209127 9620803 19151708
NOTCH1 PSEN1 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 10879540 10206645 12209127 9620803 19151708
PSEN1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10593990 10077672 16713569 10206645 12374741
PSEN2 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11518718
PSEN2 NOTCH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11518718
PSEN1 NOTCH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11518718
PSEN2 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11518718
PSEN1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11518718
NRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
SKP1 PDCD4 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17053147 17884153 18931676 19270156 19622404 19686080 19797085 19809470 19847258
PRKACA RYR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10830164 29760186 14532276 14715536
PRKCA STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 8631738 12519779 12950453
PRKCA PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14576165
PRKCA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18812399 9935181 15659650 9315650 19933256 16713569 9571186 1454855
PRKCB STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 8631738 12519779 12950453
PRKCG STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 8631738 12519779 12950453
PRKCZ PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14576165
UBQLN1 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11076969 16815845 16713569 16813565
PSENEN PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12522139 12198112 15322109 16189514 21115843 12639958
SSRP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18218727 10722927 17725714 12437983 8774705 16489119
TGFBR1 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFBR1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 18922473 22710166 23331499 19010789 16474430 22943793 17934056 20519943 12809600 21900405 11133108 18758450 14557817 15548370 19920116
TP53 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18172499 18695251 24667498 22056774 17290220 17592138 12421820 18413597 20173098 19556538 21857681 17470788 18359851 19805293 19196987 12640129
TP53 CLSTN1 â—¼   KO_UP_REGULATES ✅ + 1.23 1.23 PKG 28854368
TP53 NOTCH1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368
TDP2 TDP2 â—¼   KO_DOWN_REGULATES ✅ - -2.0 1.99 PKG 28854368