ATP2A2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
BAG2
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7834747
8692945
|
BAG6
|
DNAJB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
VDAC1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0907555106
19706527
|
BCL2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FKBP8
|
BCL2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
2.0
|
0.8
|
ACSN
|
10409669
20139069
|
TCF7L2
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17404573
23671559
|
NOTCH1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9881968
16990763
|
KRAS
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16483930
29311131
|
PSEN2
|
BCL2L1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
10446169
5211736
|
CDKN2A
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19049976
|
CASP3
|
BID
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
CASP8
|
CASP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18669646
0712034105
|
CASP3
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CASP6
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
CASP3
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17899380
|
PSEN1
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
RAD23A
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
NOS3
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
CDC37
|
APOE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
CIB1
|
PSEN2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5211550
10366599
|
DNAJA1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ERLIN2
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15050920
10579907
|
SKP1
|
FBXW7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21620836
8177582
|
JUN
|
FBXW7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21460851
20638938
|
TP53
|
HMGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6547598
9472015
|
HMGB1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HMGB1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18218727
19158276
|
PSMC3
|
HTRA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MAPT
|
ZFHX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GSK3B
|
MAPT
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
17078951
5219283
|
MAPT
|
CDK5
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
17078951
5219283
|
MAPT
|
TUBA1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
1421571
16687396
|
RAB3A
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
UMPS
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
APBA1
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217828
16007100
|
ST13
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
RMDN3
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN2
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
ECSIT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
KANK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
APOE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
ACTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
EFHD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
EPB41L3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
ENSA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
GCDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
NOTCH1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
22330899
22363130
|
PSEN1
|
DLL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
22330899
22363130
|
UBQLN1
|
PSEN1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5213196
11076969
|
CTNND1
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10208590
11226248
|
APH1B
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12522139
12471034
|
PSEN1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19012753
18996842
|
PSEN1
|
DLL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12794186
|
PSEN1
|
CTNND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10208590
11226248
|
PSMB5
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PRKACA
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RAD23A
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PSMD2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
APP
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TP53
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17184779
5219502
|
TP53
|
HSPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TP53
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11350971
10984493
|
TP53
|
CASP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TP53
|
TCF7L2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14990988
|
TP53
|
PRKCG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10614633
9895308
|
TP53
|
DKK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15229249
10777218
|
TP53
|
GSK3B
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5216887
14744935
|
TP53
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
CASP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
DNMT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
DKK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
SCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
HSPA8
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
UBB
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PSMB2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA5
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PSMC3
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PSMC2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PSMA4
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
NGF
|
TRAF6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
16252010
16630834
|
APH1B
|
TRAF6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
16252010
16630834
|
NGFR
|
TRAF6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
16252010
16630834
|
APH1A
|
TRAF6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
16252010
16630834
|
PLD1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PLD1
|
CFL1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6173882
17853892
|
RHEB
|
PLD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18550814
|
ATF4
|
CASP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
EMC8
|
EMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
PSMC3
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
UBB
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
UBB
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
NOTCH1
|
MYOD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12050162
10066785
|
MYOD1
|
DLL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15300513
10202155
|
PLCG1
|
FLNB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
NOTCH1
|
DLL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
20351093
22363487
|
NOTCH1
|
DLL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
20351093
22363487
|
NOTCH1
|
NOTCH4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22330899
22363130
|
HRAS
|
HSD17B12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
ITGB3BP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
ADAM10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ADAM10
|
APP
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20676056
10097139
|
ADAM10
|
CDH1
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18434311
15958533
|
UBC
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7104155
19343052
|
JUN
|
UBQLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
JUN
|
MAPK9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
TCF7L2
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
JUN
|
CASP8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18196534
17922191
|
JUN
|
DKK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23752183
11867524
|
JUN
|
PRKCG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20444941
7841543
|
JUN
|
HSPB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12832543
20566634
|
JUN
|
PSEN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
MAPK9
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19527717
7148309
|
GCDH
|
ECSIT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN2
|
ECSIT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
RNF32
|
ECSIT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
ECSIT
|
CYP2C18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
ECSIT
|
PSEN2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
ECSIT
|
APOE
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
RHEB
|
UBQLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RHEB
|
CASP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NCSTN
|
APH1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18201567
6174903
|
APH1A
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APH1A
|
APH1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
16252010
16630834
|
APH1A
|
APH1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
16252010
16630834
|
APH1A
|
NGFR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
16252010
16630834
|
APH1A
|
NGF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
16252010
16630834
|
APP
|
NGF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NGF
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APH1B
|
NGF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
16252010
16630834
|
CASP8
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CASP8
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10409650
10911620
|
PRKACA
|
CDH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CDH1
|
PRAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CTNND1
|
CDH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8660921
14610055
|
TCF7L2
|
DKK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15592430
15592505
|
RNF32
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
GAPDH
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CDK5
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PIK3CG
|
PRKCZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8765021
16527821
|
PRKCZ
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18667433
17646398
|
ELK1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PDCD4
|
APOE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PDCD4
|
EIF4G1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12054647
|
PRKCA
|
GAP43
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
2562806
7891109
|
APH1B
|
NGFR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
16252010
16630834
|
APH1B
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TUBA1B
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
GAPDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRKACA
|
GAPDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CASP1
|
GAPDH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17959595
|
TMED10
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ERN1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6542966
18369366
|
BCAP31
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PSEN2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
STXBP1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ICAM5
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NOTCH4
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPA8
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PSENEN
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
KCNIP3
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPA5
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
UBQLN1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRKACA
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PIK3CG
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRAM1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
RNF32
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
APP
|
HSPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
CASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11967258
12191486
|
EIF4G1
|
HSPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10859165
5212678
|
DNMT1
|
ENSA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
RNF32
|
APOE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
ST13
|
APOE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
CYP2C8
|
APOE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
HSPA8
|
GFAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9038169
9151685
|
CLSTN1
|
APBA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17332754
5219717
|
ERBB4
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16729043
17496910
|
STAMBPL1
|
RNF32
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
HSPA5
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11943137
|
TBL3
|
ITSN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
PSEN2
|
FBXL12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
SSR4
|
SSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17380188
5219807
|
CASP1
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18667412
|
PSENEN
|
NCSTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18201567
6174903
|
NCSTN
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10993067
|
CASP6
|
CASP7
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
SSR4
|
SSR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
28218252
11964406
|
NOS3
|
KANK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
UBQLN1
|
PSEN2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5213196
11076969
|
KCNIP3
|
GFAP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19238593
18579744
|
NOS3
|
GCDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
NOS3
|
GCDH
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
RNF32
|
PRAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PGRMC1
|
DHCR24
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PTGER4
|
ST13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
APP
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
TRAF6
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
31594754
30711629
31754475
30806153
|
PSMA7
|
PSMA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
6175987
17948026
|
DNMT1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
815.0
|
0.81
|
STRING
|
36370105
|
CASP8
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
APBA2
|
CLSTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
CDC37
|
GFAP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
24189400
|
RHEB
|
UBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RHEB
|
SRPRB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
EMC1
|
FKBP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32877691
27342126
|
SOAT1
|
RPN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
29128334
|
CDH2
|
CTNNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
APOE
|
MAPT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
SSR3
|
SSR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
HMGB1
|
GFAP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
29382328
|
VDAC1
|
RPN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31536960
29128334
26344197
|
TRAF6
|
UBC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
14743216
17703191
19820695
18239685
|
EMC1
|
EMC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
32439656
22119785
26496610
27342126
33961781
26186194
|
FAF2
|
UBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
18775313
|
FAF2
|
ECSIT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PSMA4
|
PSMA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
6175987
17948026
|
VDAC1
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IFT57
|
ATP9A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
SKP1
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
PSEN1
|
TMBIM6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
834.0
|
0.83
|
STRING
|
36370105
|
PSEN1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CDC37
|
CDK5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21163940
23455922
33961781
9150368
|
NCSTN
|
PSEN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
UBB
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
LLGL2
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
KRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
HSPB1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
GSK3B
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
23455922
29568061
33961781
|
ECSIT
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
29929436
10465784
31281713
|
TRAF6
|
CASP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27810922
16436380
30979779
16920630
|
PSMA7
|
PSMA4
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
6175987
17948026
|
RPN2
|
MLEC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
22988243
33961781
31831667
|
CASP8
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16183855
11406564
|
TRAF6
|
PSMD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17353931
14743216
|
COX7C
|
NDUFA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
PSMB5
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
PSMB5
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
STAMBPL1
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
CDH2
|
CTNND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
GSK3B
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
PSMB1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
PSMB1
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
PSMA5
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
PSMA6
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
PSMA7
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
MAPK9
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
9405416
|
PSMA2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
PSMA5
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
PSMA7
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CASP8
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9727492
15659383
9727491
12097160
11832478
12196516
11085743
|
CASP3
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10364179
11399776
18723680
|
CASP8
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15254227
11832478
18669646
11437602
8962078
|
CASP6
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
8900201
25241761
18723680
|
HMGB1
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22939629
29721183
26344197
|
KAT2B
|
MYOD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20364308
9659901
27453350
17964260
10944526
10619020
12887892
17468105
|
BCL2
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
SKP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
APOE
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CDK5
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
BCL2
|
FKBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
HSPA8
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
NGFR
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
HRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
RAD23A
|
UBQLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
NOTCH1
|
FBXW7
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
23022380
|
MLEC
|
RPN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22988243
31831667
30021884
|
ID1
|
MYOD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
8380166
9528857
15029197
18674781
20195544
12145280
9242638
|
APBA2
|
APBA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
|
APP
|
BACE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
DNAJA2
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
ID1
|
MYOD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
BCL2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
FBXW7
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
DNAJA1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
HSPA8
|
MAPT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
PSMD2
|
RAD23A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
IRAK2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
CDH1
|
CTNNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
KAT2B
|
MYOD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
RPN1
|
RPN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32788342
33961781
34079125
22939629
26344197
|
RPN1
|
STT3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
34079125
32788342
30021884
|
IRAK2
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33799071
21988832
9374458
33961781
26250868
10383454
17878161
21903422
|
JUN
|
MYOD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8380166
1310896
16713569
|
DNAJB11
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
CDH2
|
JUP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
PSMC3
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
HRAS
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
CASP8
|
BID
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
9727492
|
APP
|
NCSTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
CDKN2A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
FKBP8
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15905180
15733859
17942410
12510191
17379601
33961781
15990872
|
JUN
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14623928
17262823
19335069
|
GAPDH
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
NRAS
|
CDC37
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16024644
15118125
15284455
|
KRAS
|
CDC37
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16024644
15118125
15284455
|
HRAS
|
CDC37
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16024644
15118125
15284455
|
JUN
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10700231
20566634
19959471
|
ID1
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23342268
19079342
20191379
|
ZNF274
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19340300
|
TP53
|
FBXW7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23518350
19366810
12824889
|
TP53
|
FBXW7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
31346036
12824889
|
CASP1
|
IL1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18329368
|
LRP1
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
2779654
11421580
20030366
15182176
|
ELK1
|
PSEN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12928043
12750007
|
PRKCB
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14576165
|
CASP6
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10069390
|
TMED10
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17145710
16641999
|
PRKCG
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14576165
|
CASP1
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10069390
|
SCAF11
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10069390
|
CASP8
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10069390
|
ELK1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10913190
19687146
11520792
|
TP53
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15383401
20332115
21478913
|
TP53
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15212714
20097177
18840615
|
TP53
|
TMEM33
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16980608
|
TP53
|
HSPA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
31027880
18431400
|
STXBP1
|
PLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
8024366
19323535
7215275
|
PLD1
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
8024366
19323535
7215275
|
ATF4
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
1827203
20936779
23661758
|
EMC2
|
EMC8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
16189514
25416956
32439656
22119785
31536960
26496610
27342126
33961781
26186194
30021884
|
PSMA2
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
ADAM10
|
NOTCH4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19601831
19726682
19704010
|
JUN
|
NOTCH4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23917222
21679465
17220278
|
GSK3B
|
CDK5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17607942
15676027
15652488
|
PRKCZ
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24379783
|
PRKCA
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19836308
|
RPN2
|
NGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
APH1B
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12297508
|
APH1B
|
NCSTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12857757
12297508
|
PSMA6
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
GSK3B
|
GAPDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
APP
|
GAPDH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21832049
16713569
8473906
|
CASP6
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10409650
10438520
|
PRKACA
|
CTNND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
22798526
|
DNMT1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
APBA1
|
STXBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9395480
15563604
|
APBA2
|
STXBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9395480
15563604
|
PRKCG
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24379783
|
BCL2
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
FBXL12
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
CDK5
|
MAPT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
PSMC2
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
PSEN2
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
KAT2B
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
TRAF6
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
CTNNA1
|
JUP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
PSMC3
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
MLEC
|
RPN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
BCL2L1
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
PSMB2
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
PSMB2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
APBA2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
PSMA4
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
PSMA4
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
PSMC2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
SSR1
|
SSR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
CDH1
|
CTNND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
CDKN1B
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
34591612
|
EMC1
|
EMC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
DNMT1
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
MLEC
|
RPN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
RAD23A
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
FBXW7
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
14739463
31843895
30044990
29225075
16023596
28036276
33086033
29346117
|
PSMD2
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
HRAS
|
PIK3CG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
FBXW7
|
NOTCH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
STAMBPL1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
HMGB1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
PSMC2
|
RAD23A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
ERN1
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
UBC
|
UBQLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
RPN2
|
STT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
BAG2
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
PSMD14
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
PSMD2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
DDOST
|
MLEC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
958.0
|
0.95
|
STRING
|
36370105
|
UBC
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17568776
5220017
|
RPN1
|
STT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
PSENEN
|
PSEN1
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.96
|
0.96
|
Signor
|
12522139
|
APBA1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
PSMD14
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
APP
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
CDH1
|
JUP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
MAPT
|
PRKACA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
PSEN1
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
JUN
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
APH1A
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
APH1A
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
APH1A
|
NCSTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
PSMB1
|
PSMC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
NCSTN
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
PSMA7
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
DDOST
|
STT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
BID
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
19074266
11583631
9727491
9463381
15520201
14681455
17289999
18835031
12624108
|
FBXW7
|
SKP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28522751
26540345
28007894
22388891
26087183
28614300
32350066
26474281
19412162
21620836
29346117
31210753
12628165
23791182
30728155
27247421
31285543
33658012
20596027
22632967
32086376
24811168
22524983
8051045
11585921
25720964
26976582
21205095
29408378
11565034
17434132
15070733
|
PSMA7
|
PSMC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
NCSTN
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
PSMB5
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
PSMA7
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMB5
|
PSMC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
RAD23A
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
FBXW7
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA5
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMB2
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA6
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA4
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMB5
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMB5
|
PSMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA7
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
EMC1
|
EMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA7
|
PSMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA6
|
PSMA7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA5
|
PSMA7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA7
|
PSMB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA7
|
PSMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GSK3B
|
MAPT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
RPN1
|
RPN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMA4
|
PSMC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMA4
|
PSMA7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMA7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
DDOST
|
RPN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA6
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA5
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA4
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA6
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
DDOST
|
RPN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMC2
|
PSMC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA5
|
PSMC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMB2
|
PSMC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA6
|
PSMC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA4
|
PSMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA6
|
PSMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA5
|
PSMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMB2
|
PSMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMC3
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMC2
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMA4
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMA5
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD14
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMC3
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMC2
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMB2
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMB2
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EMC2
|
EMC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA5
|
PSMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA4
|
PSMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA6
|
PSMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA4
|
PSMA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA4
|
PSMB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA4
|
PSMA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA2
|
PSMA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA5
|
PSMA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA6
|
PSMB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA5
|
PSMB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
HMGB1
|
BAG6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12646658
15802534
19931333
22842346
26618107
27048821
27192565
|
BCL2
|
TMBIM6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
9660918
|
BCL2
|
TMBIM6
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
9660918
|
PRKCA
|
BCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
10677502
10679481
10871288
11323415
16492141
20027184
9115213
9738012
|
TP53
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
17693666
8183578
10037739
16738310
18397889
19521340
18487508
21666495
16294215
21656028
22869582
19714248
10744634
8174112
17592775
11782367
19137013
20428827
18682598
11713302
11313951
20501806
9649502
24814047
15767042
24098340
11193470
10329733
21859835
22266868
10953306
19555669
23638218
14684736
19411072
20530667
24155778
8205530
20840522
9000137
15326476
|
CASP3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10409669
9395403
20139069
11948397
|
FKBP8
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
10409669
15990872
15733859
17942410
12510191
17379601
20139069
|
PRKCA
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
12039060
9115213
12213578
11323415
17610064
9738012
19117992
24212628
10677502
|
TP53
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12667443
19555669
8205530
19007744
11313951
|
BCL2L1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18835031
14980220
26186194
11583631
|
BCAP31
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9334338
17145710
|
BCL2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16183855
11406564
|
BCL2
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
18835031
17145710
9463381
16697956
17289999
19074266
12624108
11583631
9727491
15520201
8918887
|
TP53
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
22869582
9582400
9989972
11713584
18172861
23519249
12705879
9000137
11713302
|
FKBP8
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16189514
12510191
15733859
|
BCAP31
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9334338
17145710
12594175
|
BID
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
9727492
19074440
16697956
15694340
17289999
25241761
22464442
14963330
16189514
27159560
24814347
15574335
|
TP53
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
24814347
12667443
16151013
26556313
14963330
16713569
20837658
24474649
21900206
|
BCL2L1
|
VDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
12767928
17209561
16189514
10365962
10737788
|
BCL2L1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
24814347
12667443
16151013
26556313
14963330
16713569
20837658
24474649
21900206
|
TP53
|
BID
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12402042
16151013
18574470
|
CASP3
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
11085742
11085743
|
CASP8
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
12196516
18458084
9727491
11085742
11085743
12097160
9873064
|
TP53
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15240700
12402042
18431400
15024076
|
CASP1
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11085743
9727491
|
TP53
|
CASP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
22154326
22178888
23677569
15578696
17363498
24098340
18064040
23527225
10893263
21859835
|
CASP8
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
15755874
17179148
9501089
9950028
18669646
23308069
10988287
18458084
16964285
9885230
9765224
11437602
15014070
21295084
8962078
9208847
|
CASP3
|
MAPT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12888622
16606369
22535953
11162250
|
CASP3
|
EIF4G1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10611228
9819442
|
CASP3
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10069390
16189514
|
CASP3
|
CASP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
25241761
17899380
8900201
9922454
18723680
|
CASP3
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10069390
9219695
9990034
|
ERBB4
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
8617201
16978839
10878805
15643424
15568014
1973074
8665853
11071886
|
PLCG1
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
17177598
16187797
15284455
16953218
17712310
|
TP53
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15145945
15988033
19235838
10516009
21478095
14984207
19427386
|
TP53
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21340684
20066118
20457558
20182602
6396087
|
SKP1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15340381
15147722
12820959
16209941
11516665
15071497
15688063
|
HRAS
|
CDKN2A
|
â—¼ UP_REGULATES
|
✅
|
+
|
15.0
|
1.0
|
ACSN
|
10358164
12134164
12447393
14764585
16102570
17673906
20841469
24027568
24954210
7510700
7673236
8551221
9069260
9763606
9846483
|
TP53
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
16103197
22467867
18555006
8631601
11402335
19649205
22020338
21164364
17265068
16764954
15775976
22056554
18275833
21483786
10348346
19216023
12384561
12091906
19901969
11360201
15205322
11818069
21892281
10980602
11739748
11559812
24672805
10097151
17907153
19244234
15361884
10652576
9436028
21447739
20569441
21555589
21637567
10816133
9774662
19240179
|
ID1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
11507043
11234019
17639499
15064751
11427735
17565736
18240291
22714536
19567783
21933340
20484992
15138269
24177224
22025288
|
PSMC3
|
CDKN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18805416
17334400
14665636
16713569
|
CDKN2A
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15856024
15989956
9724636
19960022
12740913
17158541
12640129
19590512
|
HSPA8
|
DNAJA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20084477
20809635
24012426
7828728
20072699
|
ERLIN2
|
KRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
ERLIN2
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
ERLIN2
|
NRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
FBXW7
|
NOTCH4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15592418
11585921
|
FBXW7
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
14739463
28036276
18930588
16023596
|
FBXW7
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
11425854
11461910
20571051
23331499
20823234
17909182
25344755
32792479
11585921
16713569
17646408
27229929
15546612
|
IRAK2
|
HMGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
21606490
11544529
17890055
19679662
20485341
17878161
16024789
19224918
20400509
|
HMGB1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
18070982
15247281
21220427
12140561
12138165
8837778
19592497
18347055
|
TNF
|
HMGB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10925299
11112697
11438547
11875494
12646658
12811837
1431106
14607933
14625680
15099563
15699106
16713974
17916596
18633355
19411070
20038811
20184663
20435894
21133840
21411734
21826665
22595692
22955274
23170255
23430059
23508573
23510023
23567181
23769623
24092389
24378531
26201938
8910423
|
TP53
|
HMGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9472015
23063560
11748221
16713569
11106654
|
HMGB1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9472015
23063560
11748221
16713569
11106654
|
CDK5
|
HTRA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21701498
22675361
|
JUN
|
IL1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19299558
8688489
|
TP53
|
KAT2B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9266967
20094059
15153330
17611664
18945670
14614455
17293853
|
KAT2B
|
MYOD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
9659901
10944526
10619020
|
KAT2B
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10747963
22120716
14500836
16713569
23029358
|
KAT2B
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
17145710
19680552
11804596
12068014
16537920
9891054
10490106
14614455
20589832
19788416
12660246
12501250
16959611
19407812
9744860
15965232
16678111
17977830
17189186
|
PRKACA
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12069755
19651622
11158305
|
PRKCA
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15272003
|
PRKACA
|
MAPT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
77.0
|
1.0
|
Omnipath
|
9614189
9832145
19562805
12387894
9546672
19413330
1730702
7706316
9353289
20068231
16923168
21215781
8999860
9565682
11181841
10737616
7566346
12435421
17287340
9771888
19651622
9735171
11104762
12226093
16000144
8163474
26840030
6412713
9199504
10090741
11311121
2387894
|
CDK5
|
MAPT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
103.0
|
1.0
|
Omnipath
|
16697218
26944284
21945393
9614189
7592534
9832145
19562805
12387894
21848865
27641626
24268883
9546672
12071639
19413330
1330687
19415658
15302935
9353289
21671254
20508838
8282104
20068231
26998748
16568235
21215781
17045592
9565682
11181841
7566346
12435421
17287340
9771888
15843619
17078951
22761989
24367683
19651622
1181841
9735171
11104762
12226093
9199504
18510355
11311121
2387894
28785087
|
GSK3B
|
MAPT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
141.0
|
1.0
|
Omnipath
|
19616957
22278060
25641096
9832145
19562805
12387894
24268883
9546672
31640277
21865886
19413330
28386764
28379300
1330687
28734998
19415658
15302935
17047304
7706316
27349344
29408874
9716264
9353289
21671254
24165324
12714590
20068231
12387897
17570479
16452634
25815351
21215781
16568235
16519507
8999860
17045592
9565682
27857758
11181841
14690523
22690349
27073700
21443865
10601262
7566346
10737616
15522877
12435421
17287340
9771888
29725295
15073173
17078951
19651622
1181841
15542598
9735171
12226093
11104762
21985244
20049527
28835279
27965573
20679343
20308788
9199504
18510355
10090741
11311121
2387894
|
APOE
|
MAPT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9512010
8620924
7566652
9147408
|
NOTCH1
|
PSEN1
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10879540
10206645
12209127
9620803
19151708
|
PSENEN
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12522139
12198112
15322109
16189514
21115843
12639958
|
GSK3B
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
11104755
17389597
17360711
16814287
10997338
|
PRKCA
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14576165
|
PRKCZ
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14576165
|
NCSTN
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
12603837
23331499
21071413
14572442
12471034
10993067
18201567
18988627
12032140
|
CASP7
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10069390
16189514
|
MAPK9
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18667537
|
UBQLN1
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11076969
16815845
16713569
16813565
|
APH1A
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12522139
12471034
16189514
12297508
|
CDK5
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12056836
15917097
|
PSEN1
|
NOTCH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11518718
|
PSEN1
|
NOTCH4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11518718
|
PSEN1
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
10593990
10077672
16713569
10206645
12374741
|
PSEN1
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10635315
11226248
16126725
11953314
|
SSRP1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18218727
10722927
17725714
12437983
8774705
16489119
|
CDH2
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
5.0
|
1.0
|
ACSN
|
11884419
16424155
16461340
17307799
17617594
|
CDH1
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
5.0
|
1.0
|
ACSN
|
11884419
16424155
16461340
17307799
17617594
|
DNMT1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21765477
24875904
23335796
22742857
|
JUN
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
12759366
11087751
7935377
21059644
16881863
24548427
12509451
9826775
10318823
8998076
18408586
15546613
20164416
7896795
9211933
10952728
9566900
23583459
10748079
24009130
10954918
10754326
9813054
10837498
9988757
11739517
16365438
19285436
16199883
8816436
10551799
8552071
9160673
11490006
21098092
16483936
10688670
10913190
16888805
9030359
25567680
9760243
|
TP53
|
CDK5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10604467
17591690
12064478
18490454
10500146
|
JUN
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22859294
17321721
20697347
10348347
12963547
10072388
22353755
18604200
|
TP53
|
KRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11514734
18555006
10953306
14741382
19107228
20124454
8274455
16061648
10448271
|
TP53
|
HRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21552926
9662334
11127813
21552928
|
TP53
|
CASP6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19897582
16391794
18064040
16518869
12089322
24070868
|
TP53
|
CASP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16135520
12459463
15580302
21943362
11278253
|
MAPK9
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
12356735
14665630
26158765
18778462
12969974
12861053
15254178
17135248
18669630
12384533
17363488
17698850
11283254
10706102
21454683
18931691
11551930
11397945
14612532
15064747
15963507
11175334
11423984
27147566
29234486
24657168
10581258
14517211
17353187
10673500
22030623
14527925
22728651
17525747
15629715
9393873
11447225
15671037
22285752
17245430
15140942
28673515
23871434
11078726
20041275
11896587
16731759
17121812
33514736
11861384
25431954
12810724
17967874
12955074
21832239
16818520
12756247
23798621
11526498
20009884
16713569
10202145
11850826
11896572
10710310
10570149
12959929
15269203
11583595
21148320
|
GSK3B
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
23840442
12064478
11709713
9372954
11483158
16552184
17570479
14744935
16713569
21929745
12048243
21900206
|
HSPB1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
25241761
16169070
16713569
17184779
|
PRKCA
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
18812399
9935181
15659650
9315650
19933256
16713569
9571186
1454855
|
CDK5
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
9372954
21317932
11483158
11740489
19413330
19664995
21600237
11554766
11709713
16552184
10884347
16377624
17591690
15866171
17287340
17967874
92065884
11780126
12064478
10570149
26146988
15701641
17117479
17108107
14702041
|
TP53
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
18172499
18695251
24667498
22056774
17290220
17592138
12421820
18413597
20173098
19556538
21857681
17470788
18359851
19805293
19196987
12640129
|
TP53
|
CASP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18431400
12089322
|
TGFBR1
|
TRAF6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
11013220
11133108
12154066
12717440
12724770
12767520
12809600
14557817
15265520
15548370
16474430
17673906
17934056
18758450
18922473
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
22943793
24132110
24336330
7594497
9865696
|
TRAF6
|
ECSIT
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
14660645
15125833
16252010
17948050
18264787
18758450
18922473
19161412
|
TGFBR1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
18922473
22710166
23331499
19010789
16474430
22943793
17934056
20519943
12809600
21900405
11133108
18758450
14557817
15548370
19920116
|
IRAK2
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
21988832
10383454
21903422
9374458
12659850
17878161
26250868
24973222
33799071
|
TRAF6
|
ECSIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
25371197
21525932
10465784
|
PRKCA
|
PLD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
1559964
11459228
9989263
11042115
12429840
17570479
10441128
12839565
|
STXBP1
|
PLD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
14744865
|
JUN
|
MYOD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
2167198
19723510
1313772
8120060
8264634
1310896
|
PRKCA
|
MYOD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17570479
11025438
1335366
|
ID1
|
MYOD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
12145280
9242638
15029197
8380166
20195544
9528857
1922066
18674781
|
PRKCA
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
2820980
8885868
10592173
1370476
|
PRKACA
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
1370476
2479646
|
NOTCH1
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11585921
15546612
11461910
18094723
|
ADAM10
|
NOTCH1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
18676862
19601831
19704010
19726682
22006996
|
ADAM10
|
NOTCH1
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9244301
12354787
17401372
10882063
19726682
|
NOTCH1
|
PSEN2
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10879540
10206645
12209127
9620803
19151708
|
DLL1
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17537801
11006133
9819428
21685328
1006133
16140393
98194281
22353464
|
PSEN2
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11518718
|
ADAM10
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19726682
28624438
19704010
19601831
22399336
|
GSK3B
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
16944320
15465828
12123574
11967263
14663202
8524413
21828089
16713569
9832503
15020233
|
HRAS
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
10228164
15314172
11689445
28539435
11726503
19879889
8635462
|
HRAS
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9069260
9727023
17145710
10922060
11136978
21779497
|
ADAM10
|
DLL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
18676862
19601831
19704010
19726682
22006996
|
DLL1
|
ADAM10
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9244301
12354787
17401372
10882063
19726682
|
ADAM10
|
DLL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19601831
12794186
19726682
19704010
|
ADAM10
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
32814053
30538620
12535668
|
ADAM10
|
NOTCH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12651094
23331499
19726682
19704010
19601831
|
JUN
|
NOS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11382920
17933457
20371606
16453281
18556800
17919072
|
JUN
|
APP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8063812
11677255
8015372
|
JUN
|
NGF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11905996
11733514
8717334
2111020
|
GSK3B
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
23331499
1846781
25979842
25241761
20537194
21278055
21397588
17482134
1516134
8384355
17570479
16023596
17215518
30086763
92065884
24632621
|
MAPK9
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
17143273
17145710
17637567
12584171
20506250
11948398
15378002
16824735
9687508
8654373
20028971
12788955
9305638
15302935
26091349
33822843
18362184
17875713
16393692
9405416
17570479
1922387
18252863
25561726
7737130
10490605
17189706
11896587
34408980
11274345
20178741
8525045
16076903
7992057
19527717
7600582
17215518
8985011
11801649
19118012
11278395
8001819
8137421
19436832
16533805
8945519
12881422
9315636
10385525
12093796
14523011
19910486
15212693
8157646
12040039
11562357
|
SKP1
|
PDCD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
15703371
16697054
17053147
17884153
18931676
19270156
19622404
19686080
19797085
19809470
19847258
|
NDUFA4
|
NDUFA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFS7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFA8
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFS7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
ECSIT
|
NDUFA4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10465784
15526035
16200211
16218961
17344420
20025615
20816094
25371197
26989860
|
NDUFA8
|
NDUFS7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA8
|
NDUFS7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
ECSIT
|
NDUFA8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10465784
15526035
16200211
16218961
17344420
20025615
20816094
25371197
26989860
|
ECSIT
|
NDUFS7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10465784
15526035
16200211
16218961
17344420
20025615
20816094
25371197
26989860
|
RHEB
|
FKBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
12906785
17991864
18466115
19022819
19143635
23087689
|
RHEB
|
FKBP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
12906785
17991864
18466115
19022819
19143635
23087689
|
GAPDH
|
RHEB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19451232
|
RHEB
|
FKBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18676370
18658153
17991864
19222999
|
NCSTN
|
APH1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
15189355
21071413
14572442
12471034
12857757
18201567
12297508
|
APH1A
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12471034
16189514
12297508
|
APH1A
|
PSENEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12522139
15322109
12740439
16189514
|
NGF
|
NGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10764727
11546791
11756498
12376548
12387875
14673001
15099563
15548667
15721744
16252010
16630834
17488777
17764704
22465479
23314527
25071162
9841888
|
NGF
|
NGFR
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10764727
11546791
11756498
12376548
12387875
14673001
15099563
15548667
15721744
16252010
16630834
17488777
17764704
22465479
23314527
25071162
9841888
|
NGF
|
NGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
10764727
11729324
16893414
2172988
1372492
24224055
14985763
22227462
11114882
15258592
14699954
3037029
1714587
9775403
|
BCAP31
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
9334338
17145710
12668660
|
CASP8
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10069390
9219695
9990034
|
CASP8
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18073771
9545235
10872455
18329793
9727491
9463409
|
CASP8
|
CASP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18329793
12232792
9727491
|
CDH1
|
CDH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
ACSN
|
11884419
16424155
16461340
17307799
17617594
|
CDH1
|
CDH2
|
â—¼ SHARES_COMPLEX
|
|
|
5.0
|
1.0
|
ACSN
|
11884419
16424155
16461340
17307799
17617594
|
ID1
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
23555842
16007183
17639499
17202424
|
GSK3B
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
16944320
11348595
11967263
14663202
8524413
20080742
19797085
12040186
16611981
10671551
16039586
12615961
15465828
17928543
24063632
10671552
15020233
19575820
17444818
20537194
17052453
9832503
18455992
16371461
11274345
|
CTNND1
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
7542250
17261850
22752307
9535896
7651399
12707304
23180380
24424122
12640114
11226248
29207493
10225956
12427869
21670201
22850631
20371349
20940130
25468996
10409703
14610055
7876318
22715382
10629228
19711372
8660921
10931041
|
CDH1
|
CTNNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17145710
7542250
19016843
25468996
9326449
16212417
11960376
11801604
8227214
10381631
16219695
9700170
24336504
22750944
9233779
11226248
|
CDK5
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20213743
25177270
|
CDK5
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
18833287
15178331
15917097
11877420
17085446
16554819
21947912
8131745
11517218
17459339
14970211
10341243
16705182
24610780
22112898
8764598
14557249
16223726
19455415
19090995
10936190
11146006
15944381
|
CDK5
|
DNMT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
27206849
26815200
21565170
|
CDK5
|
STXBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12963086
15489225
16189514
9933594
|
KRAS
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
10228164
15314172
11689445
28539435
11726503
19879889
8635462
|
NRAS
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
10228164
15314172
11689445
28539435
11726503
19879889
8635462
|
PRKCZ
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18353303
14657655
11481324
|
ELK1
|
PRKCA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26010542
16297876
|
MAPK9
|
ELK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9130707
20506250
8846788
8654373
20028971
17875713
16393692
26538579
11145955
11309409
8887554
26370088
8548291
15782123
8262053
19436832
12665513
12947314
11274345
|
PRKCA
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
33539947
25814956
12384459
27191895
18622039
27106139
12574113
12869534
21797845
11729179
21757745
25020117
28833096
12644458
24612481
24379783
16527893
16527820
12952971
|
PRKCA
|
GFAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
9099667
7822264
12177195
2155236
2114109
12686604
|
PRKCA
|
KRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20802526
34333552
23331499
25713064
27791178
18458061
9922370
18182391
16483930
|
PRKCA
|
CFL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
22855535
|
PRKCA
|
STXBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
8631738
12519779
12950453
|
APOE
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9202294
10559559
10428074
10842709
17116874
|
BACE1
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
30538620
22801501
10677483
20418918
12901838
10531052
10931940
32814053
28923680
28869759
19251705
|
APP
|
APBA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
12196555
12972431
11517249
9890987
|
PRKACA
|
RYR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10830164
29760186
14532276
14715536
|
PRKACA
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
15319357
12522122
34204249
10376603
31923467
16839566
33429979
34026871
16946136
10908731
10671564
16270749
11729179
12171920
26132171
11978735
17572401
24379783
10376602
16873402
|
PRKACA
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
16543730
15845746
18691976
19836308
8524413
12054501
16039586
12147701
16522636
11035810
18669648
|
PRKACA
|
GFAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
9099667
7822264
19170683
11918673
12177195
2155236
31682229
2114109
12686604
|
GSK3B
|
VDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
16288047
23993956
29682501
18381814
25296756
21530686
22995655
26883165
19720099
|
KRAS
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9727023
16189514
10542052
21779497
|
PSEN2
|
NOTCH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11518718
|
DLL1
|
NOTCH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
21685328
11006133
12482954
22353464
|
HSPA5
|
ERN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18624755
26551274
31226023
12637535
|
CASP1
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10069390
9219695
9990034
|
DLL1
|
NOTCH4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
29910816
22353464
|
CASP7
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10069390
9219695
9990034
|
PRKCB
|
NOS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
24379783
24790142
|
PRKCB
|
STXBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
8631738
12519779
12950453
|
CASP6
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10069390
9219695
9990034
|
PSEN2
|
NOTCH4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11518718
|
PRKCG
|
STXBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
8631738
12519779
12950453
|