Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAB3A PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PLD1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
APBA1 NRXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11036064
APBA1 PSEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217828 16007100
APBA2 NRXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11036064
APP APBA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STXBP1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DRD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SQSTM1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA4A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20573181 7894075
APP DLG4 â—¼   COLOCALIZATION 2.0 0.8 intact 20573181 7894075
ATP6V1H HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 CDK5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
MAPT CDK5 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17078951 5219283
CEP70 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DRD4 STXBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STXBP1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SH3GL1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NAP1L2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
TCF3 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22564737 17490644
STXBP1 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STX19 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STX11 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCB MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8903320 10327068
MTNR1A MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18930812
MTNR1A MTNR1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20859254 8087006
NCOR1 STXBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RIMS1 SYT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11438520 11438518
STX11 SNAP25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SQSTM1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SYT1 STX3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7559535 1321498
STX3 SYT1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10397765
STX4 SYT1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10397765
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
KALRN DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
STX19 VAMP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX4 STX5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25416956 32296183 34079125
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HTT SQSTM1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
TUBA4A TUBB2A â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
IMP3 RPS13 â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
HGS DLG4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16713569 12151521
STX1B STXBP1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
STX11 DISC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32296183
PARK2 SNCA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HSP90AB1 MAPT â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RIMS1 RAB3A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12578829 11343654
APBA2 APBA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
SYTL4 STX1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12590134 12101244
STX3 VAMP2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HSPA8 MAPT â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
STX11 VAMP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 10036234 16189514
APP NCSTN â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
STXBP1 PLD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8024366 19323535 7215275
APBA1 STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9395480 15563604
APBA2 STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9395480 15563604
PRKCB PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576165
PRKCG PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576165
SNCA VAMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31110017 20798282 29608598
SYT1 STX1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9010211 11438523
CDK5 MAPT â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
SNAP25 STX4 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
STX4 VAMP2 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
APBA2 APP â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
SYT1 SNAP25 â—¼   PHYSICAL_INTERACTION ✅ + 0.95 0.95 Signor 16679567
ID1 TCF3 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
SNAP25 STXBP1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
STX1A SYT1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
SYTL4 RAB3A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 12590134 11865063 11773082 26186194 28514442 16189514 12176990
APBA1 APP â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
APP PSEN1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NCSTN PSEN1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
STX1A STXBP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SNAP25 SYT1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SNAP25 VAMP2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
STX1A VAMP2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SNAP25 STX1A â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RIMS1 RAB3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12578829 31679900 9252191 11431472
PRKCA PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 1559964 11459228 9989263 11042115 12429840 17570479 10441128 12839565
STXBP1 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14744865
APP APBA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12196555 12972431 11517249 9890987
CDK5 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 18833287 15178331 15917097 11877420 17085446 16554819 21947912 8131745 11517218 17459339 14970211 10341243 16705182 24610780 22112898 8764598 14557249 16223726 19455415 19090995 10936190 11146006 15944381
CDK5 STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12963086 15489225 16189514 9933594
CDK5 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 103.0 1.0 Omnipath 16697218 26944284 21945393 9614189 7592534 9832145 19562805 12387894 21848865 27641626 24268883 9546672 12071639 19413330 1330687 19415658 15302935 9353289 21671254 20508838 8282104 20068231 26998748 16568235 21215781 17045592 9565682 11181841 7566346 12435421 17287340 9771888 15843619 17078951 22761989 24367683 19651622 1181841 9735171 11104762 12226093 9199504 18510355 11311121 2387894 28785087
CDK5 PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12056836 15917097
CDK5 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25799558 16782707 32668197 18691976 15911879 19413330 17611284
PRKCA FERMT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 32730588 25609252
TCF3 ID1 â—¼   UP_REGULATES ✅ + 7.0 1.0 ACSN 15169839 16831886 17018611 17299729 17490644 18832382 22564737
SNCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11279280 12121974
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK1 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 9614189 9832145 12387894 12766916 12765608 12414518 19413330 1330687 24116116 19415658 15302935 33961674 9716264 34493616 31178717 28066266 15324364 31065832 25573097 12801934 29298849 16165272 15883264 16115884 8166686 33952699 9565682 11181841 34536819 10737616 7566346 18315566 9771888 29760653 34480088 24301651 15542598 18055457 12226093 7488031 9199504 18510355 21731772
MAPK1 TCF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 14592976 12810726
NCSTN PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 12603837 23331499 21071413 14572442 12471034 10993067 18201567 18988627 12032140
PRKCA STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 8631738 12519779 12950453
PRKCA SNAP25 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12459461 18171919 22311984 15277518 17325194
PRKCA PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14576165
PRKCB STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 8631738 12519779 12950453
PRKCG STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 8631738 12519779 12950453
RIMS1 UNC13B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11797009 31679900 11343654 12163476
UNC13B RIMS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
VAMP2 SNAP25 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11524423 22890573 9030619 11832227 7961655
SYT1 SNAP25 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12062043 16679567 10692432
STX1A SNAP25 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10195194 9852078 20489724 11524423 7622514 10373452 7553862 10954418 9556632 7768895 11509230 10449403 16169070 8663154 17363971 11832227 7961655
STXBP1 STX1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9395480 15563604 10194441 12519779 12963086 9045631 10449403 17363971 10746715 8108429
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368