Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATF2 IL13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19487697 22849952
ATF2 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11413310 12388374
ATF2 RHOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11160903 21565167
CDK1 PKN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 31981797
GLI1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20647328
PLCG2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31575057
EGR1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12690110
PLCG1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31575057
DOT1L CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
EPHA2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0808987105 18948590
IFNG PRKCD â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
PRKCD SPHK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12391145 14532121
ESR1 PRKCD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22430216 18414489
NCF1 PRKCD â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219276 17069809
PRKCD MARCKS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8422248
PSEN1 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN1 ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN1 GCDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
SP1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10446206
ARNT TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15627257 23359428
PLD1 CFL1 â—¼   COLOCALIZATION 2.0 0.8 intact 6173882 17853892
RHEB PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18550814
NME3 NME1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CFL1 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
IL7 HGF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11564764 12184921
SRC HGF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17574028 20802513
FCGR2A PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
PLCG1 EXTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG1 IL3RA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG1 FGF23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16844695 10652257
ESR1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12603855 26790618
SP1 CCL5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19124744
CTNNB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16132617 12200448
NDUFB1 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EGR1 GCLC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22174042 19798679
PRKCA NCF1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219276 17069809
SRC RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 23027962
GLI1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19329935 19930158
VHL GLI1 â—¼   COLOCALIZATION 2.0 0.8 intact 23395608 8412047
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
HIF1A EGLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
EGLN1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 0.8 0.8 mint 7987706 20840591
HIF1A AVP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16507742 12691740
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
HIF1A CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18461556 18381421
EGLN1 HIF1A â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
HIF1A EGLN1 â—¼   HYDROXYLATION ✅ 0.8 0.8 mint 5217229 15474027
EXTL3 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ACTN1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
SRC ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
SRC SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
SRC ADRB2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219452 17170700
RALA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10675331 12110590
SRC FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8756631 18083107
SP1 EGR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20121949 7384875
SP1 PRKCE â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24825907 18249093
SP1 PRKCB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12105191 20179320
SP1 SPHK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17555548 16135093
SP1 HTR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8626793
SP1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10373535 12049196
SP1 GCNT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17530395
CTNNB1 VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983094 0606850103
IL3RA PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCA PRKCE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
PRKCA SPHK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12391145 14532121
PRKCE PRKD1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0809661105 19011111
CEBPA CSF3R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
CTNNB1 GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
F2RL3 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17158345 31160049
PRKCE SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BIN1 AMPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21779028 11231140
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 GLCE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22805760 15853773
CTNNB1 GAD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592430 12782598
ADRB2 ATP6V0B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ARNT ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17991765
ESR1 HSD3B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20410197 18511507
ESR1 AVP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11089536
ESR1 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16262660 7479947
ESR1 CHAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10037443
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
ESR1 NQO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20623181
ESR1 NME1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ADRB2 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
DLST GNAO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSD3B1 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MMAB DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FUT2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FCGR2A PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
EWSR1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16206264 10975680
FLI1 EWSR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16206264 10975680
PRKCB SPHK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12391145 14532121
CDK2 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
RHOB EPHA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB PLD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
UBE2O PLD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOB EHD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
RHOB SRC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
NEU1 VHL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOB PAK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB EPN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB GRIN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB MTMR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
ESR1 ACTN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23403292 21182205 19805454 31527615
MTMR2 MTMR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28675297 27432908 25659891 27880917
CDC42 EPHA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31871319 28628118 28205554
EGR1 SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20121949 12569082
NDUFA2 NDUFB1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
SRC PLCG1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 1689310 7510703 16713569 7682059 8657103 8885868
RALA ARF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12509462 9688545
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
VHL EGLN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22286099 17986458 26215701
RHOB PKN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 31871319 34187934
NDUFB1 NDUFB2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
NDUFB1 NDUFB9 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
PLD1 RALA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9688545 9207251
PLD1 ARF6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 12379803
RALA ARF6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 12509462
SRC PAK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16374509 12215529
NCF1 PRKCB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CUL1 CDK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 9636170 26186194 21145461 23455922
PLD1 ARF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9688545 26344197
DDR2 SRC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16186108 11884411
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
PAK2 RAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12176041 31871319
GNAI1 GNAI3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PLD1 CDC42 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 10747870
PAK2 GIT2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 26496610
PKN1 ACTN1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9030526 16189514 16713569 11802708
HIF1A SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 17024177 17418410 15780936
SRC ADRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11013230 17170700
CTNNB1 PSEN1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
ACTG1 CFL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
AMPH DNM1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
SP1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2145272 12760745
ATF2 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1387083 8382609 18385943
ATF2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23800081 10506225
GADD45G CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10973963 16713569
CDK1 NME1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18234856
CDK2 CEBPA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11684017 34002296 15107404
CDK2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11598016 19450264
EXT2 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSAD CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EWSR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12560328 18757425 20153576
EFNA5 EPHA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20228801 20505120 9245480 33961781
NCF1 PRKCD â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
PRKCD CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 25639486
PRKCB PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576165
PRKCG PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576165
PLD1 PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8024366 19323535 7215275
PEA15 PLD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10926929 24710276 18541525
PLD1 RHOA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9565577 12593858 31871319 11311142
RALA PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10611224 9207251
PRKAA2 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20231899
ARF6 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30944160 12379803
ARF1 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16054594 9688545
HTR1A GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8218170 1589591 31160049
SRC PLCG1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
EGR1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19915002 8900159
CCR5 CCL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11449371 10477718 10488147 9334377 8663314 14637022 9207005 11116158 9289016
SP1 GCLC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15342415 23133636 18245173
PRKCB NCF1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
NCF1 PRKCA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
PKN1 RHOA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 8571127 31871319 10619026 12773565 9446575 9535835
PRKCA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11284700
HIF1A EGLN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24681946 20724477 31763849 15721254 20812988 25974097 16407130 27563096 26611735 29279301 17069766 22946054 15474027 20840591 17442832 33550096 23413029 18264140 25361009 18063574 16511565 34007068 16155211 19604478 17353276
HIF1A MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17335808 18588890 20102637
HIF1A SPHK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020 18055454
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
SP1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10625617 19112177
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
PAK2 CDC42 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 25416956 9535855 17353931 20696164 10320322 20936779 9822598 16204230 32707033 31871319 21311754
SP1 ASNS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19054556 11867623
SP1 ALDH7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11943774 15781457 11438531
SP1 PTH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15890770 12810570 15001549
SP1 GCNT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17530395
SP1 HSD3B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8584035
DNM2 DNM1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCE PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10092595 12407104
PRKD1 PIP4K2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16563698
SNCA GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR1 CYP11A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11500981 20410197 18511507
ESR1 NPY â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16675543 16198490 18562618
PRKCG GRIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15936117 10862698
NDUFA2 NDUFB2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
NDUFB2 NDUFB9 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PRKAA2 PRKAB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CDK1 CDKN1A â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
PKN1 RHOA â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EGLN1 HIF1A â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
GNAI1 GNAI3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 26186194
CDK2 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 15964852
NDUFB8 NDUFB9 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
BIN1 AMPH â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 9348539 9315708 33961781 31413325
CDC42 PAK2 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
HIF1A VHL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15082527 11865071 11226425 10944113 14556007 11986208 15527772 17973296 12538644 26735336 24899725 12606543 21358672 24015760 16611863 23401859 18062927 21332579 15805242 19940151 12086861 27281823 23413029 33060856 11292862 24316222 16155211 24857547 22932900 29121446 11292861 12101228 15060148 18047470 16278378 21602890 27320910 12464182 26611735 32589900 18402654 25500545 12050673 18694926 26215701 10878807 25361009 11641274 22351759 34007068 18305400 21316481 11024059 34195792 26037477 34174286 33039559 10823831 26743088 31810986 10353251 15833858 17558023 11566883 23580587 27563096 18985005 19123984 25438054 12682018 18323857 23387829 17442832 33550096 18222538 18426857 17047048 12004076 34230460 23318261 33961781 12808024 21335603 12586829 17353276 11358837 28514442 20724477 16140212 12205091 20049704 16862177 11331613 32535973 15721254 14691445 15385570 10973499 15611064 17981124 28775317 12925778 26496610 17339318 30237125 20458141 20639890 17986458 19147576 28425505 11504942 22369643 18264140 16511565 12351678 14600153 30988076 17132228
HIF1A ARNT â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 17916562 9159130 24434214 20049704 9704006 11606485 27684187 19168635 11829741 23458834 19845609 16861921 9079689 19251694 11593383 27320910 15850782 15833858 20562859 14764593 12391259 26496610 17197389 8663540 15479785 26160453 14668441 24056783 11025203 28205554 23796364 23363003 20458141 23086815 17213817 21620138 15615775 7836384 15319539 12393189 11782478 15347669 20932347 21512126 10085255 21435239 26350169 15031145 20603618 28628118 20699359 10671489 33961781 34592152 16520375 12810720 16954218 18024476
CCL5 CCR5 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EFNA5 EPHA2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CDKN1A CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16765349 5218735
NDUFA6 NDUFB1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
NDUFA6 NDUFB2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
NDUFA2 NDUFA4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDK2 CDKN1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NDUFA2 NDUFB9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NDUFA2 NDUFA6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NDUFA6 NDUFB9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATF2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18641343 12836278 20006311 20304822
ATF2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 20068037 15356147 11490006 10748079 12509451 10688670 10318823 10913190 10954918 16888805 15546613 20018859 9826775 8816436 8552071
PRKCA ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1661585 9436983 19176525 92095966
PRKCE ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24727247 22304920 24357804 25545367 26645581 25728676
CDKN1A CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9467962 26186194 21308745 15340381 23602568 23543736 24218572 17679094 15077146 26496610 12973835
CDK1 PIK3C2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12719431
CDK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25398907 28831131 20150555 22266860
CDK2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 94.0 1.0 Omnipath 23443559 23455922 10878006 20100570 23602568 15964852 20839231 25416956 23737759 9840943 18850315 11302688 20519948 24358021 19440234 15557281 9472014 9658399 16962592 9736735 12949733 8641969 10022118 15890360 12839982 16765349 17418410 15647383 10874474 15232106 17570479 17698606 12361598 26496610 9632134 24419005 12417722 16189514 26186194 20587660 25241761 8622677 9660939 25483090 12800980 20102411 10918595 12058028 12144826 8242751 9464540 9858587 29899857 23007395 11477082 9218599 12383116 25463440 12730199 8756624 9284049 9380407 9546435 24218572 16964243 15212693 13678583
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CEBPA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15466360 9442037 12502863 8846917
DNMT3A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20473858 15616584 16131836 24957603
HIF1A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15071503 15190211 10559391 20043814 21362093
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
EGR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18316600 20368687 19508870 24384380 17307334 11502738 12690110 21642427
SP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 9580699 15978937 15557281 11064455 16103879 19584258 20301197 20935676 15961274 15361832 11274368 11842244 15489892 15302882 10212208 12796485 23184467 14529564 12806965 9819384 10321829 10649433 12434298 18270969 18850004 16081043 9183012 21858218 10809237 9618481 16298343 11574165 10362258 11384995 15659839 14744793 10030670 17090534 10733944 19318349 12665570 18202149 17516505 15033443 22001409 17885207 10485470 9553133 15345676 15694838 22427654 17556661 10506225 23066038 15979845 18636159 14527674 24821727 15899840 14755691 12151347 24589735 18210215 23877711 11953011 21311948 15528212 15790310 10878024 22132221 12782287 12773551 8995437 21184768 12379120 17026958 24451377 10601254 8557703 16810128 16533812 7499379 10625687 15389873 16706751 12727210 21325288 16818630 18419600 15041706 23235480 19244234 15694666 23329847 18509005
MAP3K5 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17325029 12820963
SP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17026958 9389648 9618481 17550342 12545156 11013220 15155580 11074002
PRKCA CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17855660 10753973 11756412 15851482 16055744 15001356
PRKCA DGKZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9716136 12890670
PRKCA EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 32413552 12040186 19568798 15567848 14585353
SRC EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24457997 28957431 26788993
EFNA5 EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 20228801 9245480 24003208 15114347 22570727 11114742 9330863 20505120
NFATC2 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 11781715 15684054 11687571 22226971 23612709 19915002 9916709 7989759 12218118 9430230 15048722 8524816 10069428 11956291 10772943 10894164 12355451 12594266 17645498 8668213 25037220 21799768 18962896 9845517 9133600 8284217 9310836 18217957 15539155
NFATC2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8668213 12560487 10760264 11911478 26903200 18097033 10688670 10913190 22844476 23583303 18217957 8816436 10952728 8552071 8046352 7982959 16027109
NFATC2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23616576 18962896 15684054 12836278 22123848 11520798 12842891 18217957 22427656 22844476 10894164 21624129 16237086
NFATC2 IL13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23796028 15229217 20368097 22226971
PRKCA NKX3-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11980664
SRC PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15851033 14970215 17569658 19366211 26876198 27203386 15961393 24211614 16982614 17570831 23329791 23329794 15541367 18550549 22689788 28637715 14715667 29422059 17658731 10319993 19138410 11927579 29452094 19632318 15337529
PRKCD PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15212693 11741879 11948398 23109817 21726532 10867018 15024053 15383279
PRKCD GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15894802
PRKCD ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11809767 11146000 1848190 8083204
PRKCD CHAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15381704
PRKCD NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8626435 17069809 23109003 12734380 96198102 16297854 9857051 11145703 7657821 10336447 12056906 94375440 8089108
PRKCD FLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 26055516 22591006 19158279 25707716 22829238 21321929 24708674 24058639
PRKCA PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14576165
PSEN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 17145710 11168528 16126725 11226248 2195779 11161700 12070348 9738936 10037471 18070361 9632714 10092585 9223106 12297048 16306047 10341227 9852041
HIF1A TNF â—¼   ENZYMATIC_REACTION ✅ 28.0 1.0 ACSN 10754326 10804084 10952726 11875494 12907458 14660645 15465827 15644117 16110315 16127144 16878026 17404308 17485448 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 23390297 24006507 25043024 25103413 25732824 7594497
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
SP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 23733894 12759366 27030318 22534375 7649977 12509451 12378384 15175554 18357389 10829018 11390427 17897957 18218727 8258705 12560487 17047073 21320120 7918637 16847329 10559188 18930140 20068037 1618817 21784970 10688670 10913190 17307735 18467438 21411747 11500175 20221720 20701940
HIF1A TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21386799 17451682 15604270 17548584 17884817 15925386 22320863 23359428 23085511 19766100 16007254 12479793
EGR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 24337575 20653771 12509451 18675783 21841136 20332214 8773576 14767560 23872552 14722058 11856733 11739517 15640148 12560487 11997234 17537727 7918637 9407088 18157146 23632636 16317093 15659537 18651635 11520792 10913190 10419778 23184950
PRKCA PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 1559964 11459228 9989263 11042115 12429840 17570479 10441128 12839565
RHOA PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11102529 12593858 9565577 11311142
HGF CRKL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10871282 12138161 11146548 10753869 10618718
CCR5 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520 15251452
RHOA ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
CDC42 ACTG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
SP1 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9223667 17967179 12482909
PLCG1 SRC â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483
PLCG1 PAK2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
PLCG1 SRC â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483
IL13 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 12223527 12401408 14610620 14657224 15099563 18250477 18451175 20184663 21097505 26755705 7890616 9535722
PRKCA PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 2820980 8885868 10592173 1370476
SRC PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 8388373 16497976 16126727 16713569 17389395 1689310 20068231 17570479 16153436 16038803 1708307 7682059 7510703 18594017 12601080 8885868 8657103 17016520
RHOA PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12071848
PRKD1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19651622 8885868 20068231 1370476
IFNG HIF1A â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
IL4 IFNG â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
SP1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24019072 17023546 12576336 8756632 18793716 9503023
CCL5 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 16298345 10488147 28381538 10699158 22633458 9289016 12213786 8663314 11449371 10318947 12964882 25923671 9207005 23480650 11116158 10477718 14637022 9334377 9790730
DVL1 FRAT1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10428961 16288291 16940750 19751508 22270359 8666229
DVL1 FRAT1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 10428961 16288291 16940750 19751508 22270359 8666229
GNAO1 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19705439 19561403
DVL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 25241761 10806215 20006983 15735151
CEBPA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22685373 25119735 8999951 18199703
HIF1A CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17082639 19491109 17488804 21925595 23144021
ESR1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15208657 16029657 19440537 14991571 18669446 17932106
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
NDUFB9 NDUFA2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA6 NDUFA2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFA2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB2 NDUFA2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB1 NDUFA2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA2 NDUFB8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA6 NDUFA2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB1 NDUFA2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFA2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB2 NDUFA2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFA2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA2 NDUFB8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB2 NDUFA4 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 12601012 12667446 15186778 15526035 15807660 16200211 16218961 16246152 17344420 18485875 19131594 20025615 20816094 23850759
NDUFB9 NDUFA4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFA6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFB8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB2 NDUFA4 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 12601012 12667446 15186778 15526035 15807660 16200211 16218961 16246152 17344420 18485875 19131594 20025615 20816094 23850759
NDUFB9 NDUFA4 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFB8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFA6 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFB1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB1 NDUFA6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFA6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB2 NDUFA6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA6 NDUFB8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB1 NDUFA6 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFA6 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB2 NDUFA6 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA6 NDUFB8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB2 NDUFB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB1 NDUFB8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB2 NDUFB1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB1 NDUFB8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB2 NDUFB8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB2 NDUFB8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
GAPDH RHEB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19451232
NCF1 RAC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
PRKCB NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16375898 8626435 31811262 17069809 11120743 23109003 30093530 12734380 96198102 32531347 27809835 11145703 10336447 12056906 94375440 8089108
PRKCA NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17069809 9857051 11145703 23085266 24632950 17570479 23002436 17217339 23119229 8626435 12734380 96198102 94375440 8089108 24970888 15657040 7520867 31736979 10559253 22460559 12056906
IL4 IL13 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
IL4 HIF1A â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
SP1 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14603527 15739164 11133225 12905482
IL13 HIF1A â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 12223527 12401408 14610620 14657224 15099563 18250477 18451175 20184663 21097505 26755705 9535722
RHOA PKN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8571127 12773565 16189514 9446575 10619026 9535835
ARNT HIF1A â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
HIF1A EGLN1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
EGR1 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18506761 20448047
HIF1A EGLN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23487784 12839937 22075993 20574527 15563275 19628018 18072750 24558194 22451659 16157596
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
HIF1A GAPDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19828020 12193088 15967517 21338575 11955624 15132953
HIF1A HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19828020 15620698
HIF1A EGLN1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 16.0 1.0 Reactome 11292861 15652751 17182618 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907 15987702 22286099 18337469
EGLN1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19604478 20840591 16511565 23413029 12351678 15474027 22946054 15652751 16407130 25361009 31763849 32755251 16391536 15721254 20724477 24145445 17353276 18264140 26611735
ARNT HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17213817 8816435 17197389 14764593 12393189 12810720 15319539 23363003 9079689 11829741 15479785 26496610 12391259 17916562 24434214 11606485 20562859 9704006 21620138 11782478 20932347 15347669 8927054 21435239 19168635 9159130 14668441 20049704 20603618
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704
SRC CDC42 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
PRKCB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
ACTN1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 16291744
PRKCQ SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 17496910 11940581 21386996 10527887 2996780 11447289 19615955 16488589 6321473 8321321 12845332 11313945 2136766 17570479 12040186 19568798 15567848 14585353
PRKCE SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 11834516 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCG SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
GNAI1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 10753828 9722546
SRC CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14506284 26816343 9626657
SRC PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 30819914 12181444 11606584 14656219 7682059 15144186 11507089
SRC DNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 7505438 12011079 9880482 11956154 15834155 19380485 9539797
SRC DDR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 28270508 11884411 16186108 18083107
SRC PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12637538 28174535 28842658 17804414 12505989
SRC CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19802004
SRC PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16374509 12215529
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
SRC SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15212693 12893833 11162638 11744621 28671665 24860424 11078745 12096713
CDC42 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8107774 10559936 25416956 10320322 23331499 15020669 11340065 15003621 20936779 10934474 11413130 17353931 9535855 11950587 19628037 32296183 16204230 20696164 11248548 9822598 18719708 10613909 9823899 10461188
PRKCQ GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15894802
SP1 CYP11A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10459866 10383457 20371701 9013760 12217897 10446912
SP1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20427719 18044710 9282327 8349585 10826704 10082539 12637574
SP1 GRIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11571288 7706322 12425938 20381604 15950782 9748305
SP1 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24315822 7829523 15576380 2677669 1846185
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 PCYT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10216289 12794070 16484221 20096375 10744779 17384411 16157598 15247247
SP1 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19145069 11327698 12105191 11578973 12727210 17257588 15533438 18295514 11336542 9756852 17509747 20092859 12694408 19464346 11060301 15380450
SP1 NPY â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2376581 8123590 12760745
EGR1 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789819 7829523 9571041 7559515
PRKCA MARCKS â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1527003 7989336 9808756 11588141 8132675 17081983
PRKCA EWSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9341188 17570479 934118 11313922
PRKCA CHAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15381704 10861222 12486117
PRKCA ATP2B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9824678 11779484 1827443
PRKCA GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15894802 9242710
PRKCA GRIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8316301 14973229 93302854 10049997 15936117 9030583
PRKCA MARCKS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 17081983 20166139 18767875 17322306 1650359 11162562 1560845 19413330 19664995 8034575 6957862 21762971 18578522 91317794 20068231 11930178 18452278 17570479 16116087 18491316 18669648 17962038 8557118 17287340 15316066 8422248 19651622 20058876 15239673 17924679 2473066 19664994 18707149 18510355 15212693 18212344
PRKCA ACO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15263083 15636585 17570479 16424901 8262977 15212693
PRKCA PEA15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 19651622 20068231 9721757 17287340 15917297
PRKCA DNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 29044420 28049841 26627835 10766777 19605734 8063723
PRKCA PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15212693 18337243 11741879 11948398 17570479 34010649 10197446 10867018 15024053 15383279
PRKCA CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22855535
PRKD1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26895471 19141652 29108267
CEBPA CSF3R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17082780 10233885 10453008 11830484 11753385 11978795 8695841 20864248
CEBPA GAPDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12842822 7864870
PLCG2 PAK2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
RHOB PKN1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14514689 21351730 10619026 9988689 18006505 24128008
PKN1 MARCKS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 44.0 1.0 Omnipath 17081983 20166139 18767875 17322306 11162562 19413330 19664995 18578522 91317794 20068231 11930178 16116087 18669648 17114649 8557118 17287340 14963034 19651622 20058876 18707149 18212344 15708490
CCR5 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520 15251452
PRKCE GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15894802
PRKCE CHAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15381704
PRKCE GAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15147202
PRKCB MARCKS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17081983 20166139 18767875 17322306 11162562 19413330 19664995 18578522 91317794 20068231 11930178 16116087 18669648 8557118 17287340 8422248 19651622 20058876 18707149 7588787 18212344
PRKCB EWSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19076070 9341188
PRKCB GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15894802
PRKCB CHAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12486117 15381704
PRKCG GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15894802
PRKCG CHAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15381704