Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ACTB PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11373276
ACTB WDR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ERBB4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16912174
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
PRKN2 1433Z â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32929329 25959826
VCAM1 1433Z â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SSH1 COF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25100728 12684437 16713569 21525957 11832213 32015554
PRKN2 COF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32929329 25959826
VCAM1 COF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
PCBP1 COF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 26344197
COF1 ERBB4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 24658140
ESR1 COF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25640309 19805454
ANLN COF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
MYC COF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
PRKN2 TPIS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32929329 25959826
PRKN2 PCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32929329 25959826
CAP1 ACTS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TPIS EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
ACTC ANLN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 30890647
EGFR ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
ANLN WDR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
MYC PCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
VCAM1 PCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ESR1 1433Z â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 19805454
EGFR COF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31980649 24658140 20029029
COF1 COF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25416956 21516116
MYC HS105 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17314511 26887051 29467282
ESR1 HS105 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27483141 31527615 19805454
1433Z TPIS â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15161933 31536960
1433Z PCBP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15161933 17361185
COF1 ATX1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32814053 16713569
COF1 TPIS â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12359716 16189514 16713569
MYC ACTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29467282 11839798
COF1 PLD1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17853892 33784016
LIMK2 COF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10613909 10436159 11418599 9655398 23082153 11340065
LIMK2 LIMK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9089416 8980133 33961781
ARRB2 COF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17500066 17620599
ARRB1 COF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17500066 17620599
SSH1 1433Z â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27432908 28514442 19371722 28675297
ESR1 ACTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20308691 19805454 21182205 21182203 31527615 20348541
MYC ANLN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282
EGFR ARRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
ACTC CAP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 30890647
LIMK1 1433Z â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12323073 12361576
1433Z ACTB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15161933 17361185 20618440
ACTB COF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32296183 25910212 21516116 25416956 16189514
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
CAP2 CAP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 8761950 16189514
COF1 CAP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
COF1 1433Z â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15161933 12323073 12361576
COF1 ACTS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21723825 10366597 16713569 16189514 11950878 11707283
WDR1 COF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26344197 10366597
ACTB COF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 25416956 16713569 29892012 16189514 32015554
SSH1 ACTB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 11832213
CAP1 ACTB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 8761950 34079125
EGFR ARRB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
ATX1 1433Z â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12757707 20037628 32814053 25959826 16713569
1433Z EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 15389569 15657067 24658140 31980649 23956138 15225635 25402006
LIMK1 COF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17500066 11925442 12963706 16456544 10436159 17853892 11418599 9655398 19424295 15220930 23082153 16278681 16713569 20133759 23093407 11340065 32015554
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
LIMK1 SSH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 15660133 7600543 8217581
LIMK1 SSH1 â—¼   COLOCALIZATION 3.0 0.9 intact 15660133 7600543 8217581
SSH1 LIMK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 15660133 7600543 8217581
ACTB ACTC â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 33961781 30890647 8913639 16189514 34079125
COF1 CAP1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 26186194 16713569 28514442 16189514 11950878
COF1 ACTC â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 30890647 12207032 16713569 16189514 30021884
HS105 COF1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 14733918 16713569 16189514
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489