Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ACTB HSPB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 26465331 0133994
ACTB WDR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ACTR1A CAPZA2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HSPB2 AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18266962
AKT3 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22505453
TP53 ANLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1301998
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
TP53 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16917513
CFTR CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12208510 5215704
CAPZA2 HSPB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 26465331 0133994
GRB2 CAPZB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
STAT1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19061877
TP53 CSNK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
DAPK1 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
TP53 DAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24217921 20943371
DAPK1 TLN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16476779
GRB2 DBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
HSPB2 DCTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 26465331 0133994
DCTN1 HSPB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 26465331 0133994
DCTN1 HDAC6 â—¼   COLOCALIZATION 2.0 0.8 intact 5215415 12024216
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
GRB2 SYNPO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP1CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MYO1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBA1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IQGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
WDR1 HSPB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 26465331 0133994
TP53 NDN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10713459 10347180
SYVN1 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SYVN1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 17170702 5219455
TP53 TNFRSF10D â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16230375
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
ANLN COF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
BIRC3 UBP7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30948266 23524849
WDR1 CH10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 26344197
PURA2 WDR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 27684187
ANLN FLNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN SYNPO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN WDR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN MYH9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN CAPZB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN MYO1C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
WDR1 ATRX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BMI1 CAPZB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CFTR DCTN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
WDR1 POTEE â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UBE2K WDR1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
UBP7 WDR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32601462 26496610
MYH9 ACTB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22366308 26496610 16186248
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
NDN TP53 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
DAPK1 CAPZB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 32707033
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CFTR LIMA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
CFTR MYH9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 22038833
GRB2 FLNA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21706016 17474147 12577067
LIMA1 ACTB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
FLNA MYH9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
ACTB ACTR1A â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
SOX2 FOXC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
TUBA1B TUBA1C â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ACTB CAPZB â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BMI1 UBP7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20601937 25605328 20800574
DCTN1 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8955163 16189514
GRB2 MYH9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20936779 24189400 12577067
WDR1 COF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26344197 10366597
ACTB COF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 25416956 16713569 29892012 16189514 32015554
CAP1 ACTB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 8761950 34079125
CANX VCP â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CAPZB DCTN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 27173435 26344197
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
SRPK1 U2AF2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CSNK2B WDR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GRB2 TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12005431 9566877 7997267
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
TP53 SYVN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 TNFRSF10D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16230375
ACTR1A DCTN1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
COF1 CAP1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 26186194 16713569 28514442 16189514 11950878
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
ACTR1A CAPZB â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
DCTN1 MAPRE1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
CAPZA2 CAPZB â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
SYVN1 VCP â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
AKT3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
CSNK2B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12432063
CSNK2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10606744 11709713 10214938 10951572 16713569 11551930 10747897 10673501 11883897
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
DAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 15355354 17297916 32266931 26626260 27753536 15254178 27681874 22112863 10734067 11883897 21386980 22815859 20851891 11244509 10733583 15542844 26742101 10673501 12091386 18246126 25584963 15489221 20959462 11258706 10801407 10606744 11707453 17339337 12111733 17977830 25229255 34168813
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
STAT1 FOS â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
STAT1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8874187 7510676 8830676 12600988 7507205 8770944 17558387
VCP KEAP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
MYH9 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
NDN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24722188 10347180 16713569 23785149
PPP1CB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16501611 15178317
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066