Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BARD1 SETDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
TP53 BARD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14636569 15782130
NEDD4L ARHGDIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBE2K BFAR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BTF3 TTC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HTT CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP3 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216271 12657644
HTT CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16777606 10770929
HTT CCNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRIM39 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MCTS1 DENR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
HTT DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DYNLL1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2CA EIF4E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20927323 8288108
PPP2CA EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20927323
MYC HERC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
HTT HMBS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HYPK HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PFDN5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TPI1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF183 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PICK1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STRAP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10529175 9724739
MYC TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
MYC RAN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23468463 11085504
PAFAH1B3 PAFAH1B2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PAFAH1B2 TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
TUBB2A PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PAK3 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PCBP2 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PPP2CA PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
TIPRL PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17384681
PSMD9 TRIM39 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
WWP2 PSMF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PSMF1 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
RANBP1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12649209 5216249
TUBB REL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBE2K RING1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF126 UBE2D4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBE2K RNF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TAB1 RNF31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16260783 16953224
UBE2D2 RNF5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
SETDB1 TPI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TUBB TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18812399 8008642
TRIM27 UBE2K â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
UBE2K TRIM31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRIM39 UBE2D4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
ARPP19 PCNP â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CRK PFN1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DENR PSMD9 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
NEDD8-MDP1 UBE2NL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PCBP2 PCBP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
TUBB4B UBE2V1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
NAA10 NACA â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
DENR MCTS1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
UBE2NL UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HYPK NAA10 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
TUBB2A TUBB4B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
LRRK2 DFFA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
MYC PCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC NXF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
NXF1 STRAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22658674 16014633
PCBP3 PCBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34133714
STRAP TSN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TUBB2A TUBB4B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
LRRK2 YWHAE â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
RNF126 UBE2D2 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
GMFB PPM1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
UBE2K DDX58 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32513696 17719635
PPM1A PPM1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PAICS PPAT â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RLIM UBE2D2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
BRCA1 UBE2N â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
AMFR UBE2D2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
RAN NXF1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12384575 10228171
KIF5B TUBA1B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
TUBA1B TUBB4B â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
OTUB1 UBE2V2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
BARD1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
EIF5A PFN1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
NAA50 NAA10 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 16507339 19480662
HYPK NAA50 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
KIF5B TUBB2A â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
PARK2 UBE2G1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
PFDN6 VBP1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
VHL PDCD5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24469044 17353931
RANBP1 UBE2L3 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PFDN5 VBP1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
NAA10 NAA50 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MYC PFDN5 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
VBP1 VHL â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
AMFR UBE2G1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TUBB TUBB2A â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TUBB3 TUBB4B â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PAK2 PAK3 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ATG5 ATG3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 20562859 24186333 28514442 33024031
PCBP1 PCBP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23640898 27684187 16713569 26344197
TUBB TUBB2A â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
OTUB1 UBE2D2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
RNF31 UBE2L3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
RING1 RNF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PFDN2 VBP1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
PARK2 UBE2D2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
GART PAICS â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PARK2 UBE2N â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CCNB1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9244350 16713569 23246971 11278247
UBE2D2 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8379996 22124327
PFDN2 PFDN5 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
UBA6 UBE2D2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
UBA6 UBE2Z â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
HERC5 NME2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18535780
MYC DCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
ARHGDIA UBE2R2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CASP3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12149654
CASP3 DIABLO â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14960576 11257231 9230442
MYC CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10899308 17093053
EIF5A DOHH â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 17213197 16533814 14622290
ENO1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18490439 19219071 2191300
ENO1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
UBE2N HERC5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16112642 16428300 16122702
MYC HINT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC HMBS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PFDN6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC STMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PDCD5 NUDT3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RNF126 NUDT3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NUDT3 NUDT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TBCB TBCE â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
UBE2L3 UBE2V2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ITCH UBE2D2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
NEDD4L UBE2L3 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
HIST1H3A SETDB1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
PFDN2 PFDN6 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
TRIM50 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
TUBB TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TUBA1B TUBB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
HYPK NAA10 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
PFDN5 PFDN6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
TUBA1B TUBB2A â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
PAFAH1B2 PAFAH1B3 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
STMN1 STMN2 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
UBE2L3 WWP2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
RNF5 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
TUBB2A TUBB3 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
GART MTHFD1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BTF3L4 NACA â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
KIF5B KLC1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
UBE2N UBE2NL â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
RAN RANBP1 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
NACA BTF3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 24981860 26344197 21203952 30948508 33644029 10982809
TUBA1B TUBB2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
NAA10 NAA50 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
ITCH UBE2L3 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PPP2CA PPP2R4 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CCNB1 FZR1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ATG3 ATG5 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CACYBP SIAH1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RNF31 UBE2D2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
NEDD4L UBE2D2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PPP2CA TIPRL â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
OTUB1 UBE2N â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BTF3 NACA â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
PARK2 UBE2L3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NUTF2 RAN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DENR MCTS1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 VBP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
BARD1 BRCA1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 PFDN6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN6 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MYC NME2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15530864 14519204 11960382 19435876 18414489
BRCA1 BARD1 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 BARD1 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 99.0 1.0 Omnipath 16403807 16391231 28262780 15159397 25652403 26350354 26490435 14647430 11927591 25184681 16713569 11526114 35203293 9738006 12732733 24289923 11573085 18936166 23086937 24085845 12890688 15855157 24695549 19369211 9798686 11257228 11498787 12700228 11925436 10477523 19176389 23680151 25634209 23416467 34726323 29355525 18369654 14636569 11504724 12951069 19117993 20060929 17873885 14638690 18493658 11278247 15184379 22110403 11301010 11773071 12431996 10635334 20029420 9788437 17664283 21901007 25252691 12485996 10026184 12438698 17525341 16489000 8944023 15265711 12419249 20681793 9342365 27239795 20215511 25823446 19916563
ATG5 ATG3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
USP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
CASP3 DFFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11406587 25241761 12655299 18723680 9786842 9422513 9422506 16189514 9108473 11752060
CASP3 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9712143 9171063 11070003 9786869 16204230
TP53 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12874009 14627709 10051609 11313928 17942917 11892838 15710382 20395210 19470724 12379461 11071927 11522645 15737644 11162602
MYC CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 11522645 11983916 19470724
RNF125 DDX58 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17460044
DDX58 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16177806 17020950 15210742 15210743 23950712 16306936 16127453 17468758 12702806 17327220 16858409 16281057
MCTS1 DENR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17878526 16169070 32296183 21516116
MYC DFFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 18500556
PPP2CA EEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8386634 2555220 2176079
MYC EIF4E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18593934 15094771 8756633 12695333 24814906 14519204 22456335 16112647
MYC EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18593934 16915296
ENO1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10082554 10528225 17595061 10802057 19846662 11134351 23421821 10403782 18490439 14506152 20886042 7880838 2005901 9074493 18070418 21559732 9119380 20412594 10681589
HLA-B PTPN11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
HTT PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19240112
PCBP2 ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19881509
PPP2CA MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18039929 16680151 1716348 10995457 18042541 18588945 20626350
PPP2CA MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945 20626350
MYC MTHFD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 12808131 18414489
MYC TPI1 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 14762718 15199147 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
MYC SRM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11085504 12695333 14519204 11983916 20103729
MYC PAICS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333
MYC PPAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14519204 18628958 12695333
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
PAK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 25326649 16081735 14749374 22020439 29695509
PPP2CA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151 15048125
PAK2 NF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 28007610 17081983 20302846 15378014 18071304 11719502 11782491 14981079
OTUB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22367539 21130715 24145445 21763684 35500217
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
RANBP1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 11832950 12649209 9111043 10811801 7603572 9315840 20805321 7891706
UBE2K RNF138 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16714285 25416956 27173435 32814053 32296183 19549727
TP53 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20181957 20421190 14985507 11852084
TP53 SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12077306 12438652 14985507 15326481
VHL UBE2D2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215