Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PCNA CHAF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
PCNA POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9660172 2165567
PCNA CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
SETDB1 SLC38A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LRIF1 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
TCERG1 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
BARD1 SETDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
TP53 BARD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14636569 15782130
H3F3A H3F3B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
H3F3B H3F3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3C HIST2H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3A HIST2H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3D HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3G HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3H HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3I HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3G HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3H HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3G HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 BTBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 BTBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LUC7L2 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
LUC7L2 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LUC7L2 ATRX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LUC7L2 ULK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CBX8 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
TTR H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H3C2 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242053 5213683
H3C2 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
CREBBP H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
SETDB1 GUSBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GUSBP1 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 GUSBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 AIFM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
AKT1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
PPA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18948619
TP53 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TSC22D1 ASAH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 ASAH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SP1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
SGTA BAG6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
SETDB1 BAG6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BAG6 SMN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BAG6 CDK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MDM2 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17347673 5219751
TP53 BHLHE40 â—¼   COLOCALIZATION 2.0 0.8 intact 17347673 5219751
SETDB1 C11ORF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 CBX8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 CCDC106 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 CCDC106 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CCDC106 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 7680651 20159018
MCM2 CDK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
MCM7 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16289477 5218065
HNF4A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17885207
PML CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10356361 16007146
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
TRIM28 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942393
PPARG CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15041706
RNF10 CLSTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
ETS2 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12658630 18319327
SP3 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12200429 20096088
POLA2 CRELD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CRELD1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 CRELD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 DAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DAXX TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 14557665 5216762
SETDB1 DLEU1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 DLEU1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DNMT1 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 17584191
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
DNMT3B DNMT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20426865 15362956
DNMT3A POU5F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21608077 22867868
UBE2I DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18762900 11735126
DNMT3B SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16371653 17584191
DNMT3B EHMT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16371653 17584191
SETDB1 ECSIT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
JARID2 EHMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19010785
ETS2 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7731694
ERG VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8895512
TP53 ERH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 ERH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ESCO1 KDM1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20331966
SP1 ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20045441 12560478
ETS2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8649821 10510472
ETS2 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12750288
POLA2 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EZH2 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980680 17584191
FLYWCH1 SETDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 GIPC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 GPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HDAC1 GPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17895379 0706736104
SETDB1 GSTO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H3F3A H3F3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
PPARG HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21151932 16431920
UBE2I HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
HIST2H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SETDB1 HMOX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HNF4A TTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8931989 20735474
HNF4A TTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11544200
OLFML3 HSPB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 HSPB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RNF10 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A SMN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUMO2 KDM1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19394292
LRIF1 SETDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
MAD2L1BP SETDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 MAD2L1BP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 MAP1B â—¼   COLOCALIZATION 2.0 0.8 intact 18656471 6700545
UBE2I MBD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17066076 16757475
MCM2 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MCM6 MCM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
PPARG MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12677008 20300579
TP53 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15899946
UBE2I MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12393906 20972456
PML MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
MDM2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 5216620 12915590
PTPRS MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM MRPL44 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 NIPSNAP3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NUDCD3 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SETDB1 OLFML3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 ORAI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SP1 PAX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20435036 18314536
SETDB1 PCDHA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PCDHA4 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 PGAM5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 PHF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 PLEKHA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
SETDB1 POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
POLA2 ULK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 PPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 PPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 PPP1R8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 PRKRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM PSME1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 PTPRS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 PTPRS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 QTRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TARDBP RBBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SETDB1 RNF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RNF10 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SETDB1 S100A10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 SERPINB9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 SERPINB9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TCERG1 SETDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
SKIL SETDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SETDB1 ZNF24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 TTR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 TK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 ZFP64 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 ULK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 THAP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 TOLLIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 TRIB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 SNIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SETDB1 TRIM16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 TOB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 SULT1E1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 TXNDC9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 USP11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 TRDMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 TPI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
SIN3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 26181367 22028823
VIM SIRT6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBE2I SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
VIM SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I SNIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 SULT1E1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1004248107 20534433
SUV39H1 WIZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
TP53 THAP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 ZNF24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 TRAF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12788948 16969126
TP53 TRAF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12788948
VIM TRIM28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBE2I TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18082607
VIM TTR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HIST1H3J HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3H HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3D HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3E HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3I HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3F HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3G HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3B HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
EHMT1 WIZ â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MDM2 AKT1 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
AKT1 MDM2 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
HNF4A SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15651981 16713569 19115260
UBE2K MDM2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 23933584 21965653 30017913 15280377
SP3 SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12414801 11517158 10825178 16734381 9329821 23825960 12200149 15247906
MCM4 MCM5 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HIST1H3A HIST1H3F â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
DNMT3A DNMT3B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
ARAF AIFM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 29777862
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
CDK4 BAG6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16169070 17353931
DNMT1 CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12867029 17470536
DAXX CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24981860
CBX5 EHMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20562864 24981860
CBX5 WIZ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20562864 24981860
CBX5 SUZ12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 20562864
CTR9 DISC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29961565 31413325
EZH2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
REST EHMT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17468742 15200951
PML EZH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 17560333
GPS2 HNF4A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 17895379
HDAC1 WIZ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRAF4 KDM1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23455924 32296183
PML PPARG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20211142 32929351
SIN3B SIN3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
DAXX H3F3A â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CHAF1B RBBP4 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DNMT3A H3F3A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DNMT3A H3F3C â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
H3F3A MCM2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
HIST2H3A MCM2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
HIST2H3C MCM2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
HIST4H4 MCM2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
DNMT3A HIST1H3H â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3D â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3E â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3I â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3F â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3G â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3C â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3B â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST3H3 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
ATRX HIST1H3H â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST1H3D â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST1H3E â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST1H3I â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST1H3F â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST1H3G â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST1H3C â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST1H3B â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX H3F3C â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST2H3A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST2H3C â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST3H3 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX H3F3A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
H3F3B SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3H SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3D SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3PS2 SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3E SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3I SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3F SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3G SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3C SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3B SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
H3F3A SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
H3F3C SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3A SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3C SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
CREBBP HIST2H3D â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3J â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST1H3J â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST1H3H â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3H â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST1H3D â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3D â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST1H3E â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3E â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST1H3I â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3I â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3F â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST1H3F â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST1H3G â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3G â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3C â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST1H3C â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST1H3B â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3B â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST2H3C â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP H3F3C â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP H3F3A â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CREBBP HIST2H3A â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST3H3 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CBX5 EHMT2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
PAX3 DAXX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11244500 10393185
HDAC1 EHMT1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
KDM1A EZH2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31130994 23455924
EZH2 SIN3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27634302 24981860 27705803
RBBP4 SIN3B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 27705803
CBX5 HIST1H3H â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3D â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3E â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3I â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3F â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3G â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
AKT1 CDKN1A â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 31575057
CBX5 H3F3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 H3F3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST2H3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST2H3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
DNMT3B HIST2H3D â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3D â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3C â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3B HIST2H3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3B HIST2H3C â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
CHAF1A CHAF1B â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
ATF7IP SP1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CBX5 DNMT3B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MDM2 TP63 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
TRIB3 AKT2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12791994 30071535
CBX5 ATRX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10699177 20110566 15882967
DNMT3B EZH2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HDAC2 PML â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HNF4A SUMO2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 22505616
RBBP4 SP3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12091390 12943729
SIN3B REST â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10570134 15197246
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ATRX HIST1H3J â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CHAF1A RBBP4 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST2H3D HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3H HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3D HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3E HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3I HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3F HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3G HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3C HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3A HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3C HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3A HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3C HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
DAXX HDAC1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CDYL HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
DNMT1 HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
HIST1H3B HIST1H3J â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
BARD1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
DNMT1 EZH2 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
CBX5 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 16415788 5218238
H3C2 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 20871592 8087215
H3C2 CBX5 â—¼   PROXIMITY ✅ 0.85 0.85 mint 25281560
AIFM1 PGAM5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29568061 34079125 27218139
AKT2 AKT1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 11546794 11278835 12149249 14500673 9736715 12176337 28514442 11445557
SP3 HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11517158 17906119 16734381 12200149 17548428 12176973
RBBP4 SP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12091390 16713569 12943729
H3F3B HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
MDM2 UBE2K â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
H3F3B HIST1H3A â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
HIST1H3J SETDB1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
HIST3H3 SETDB1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
MCM3 MCM5 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CREBBP H3F3B â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
EHMT2 MIER1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21258344 18451879
EHMT2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21258344 26028330
HIST1H3B HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3PS2 HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
DAXX DNMT1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
EHMT1 EHMT2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ATF7IP SUMO2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CREBBP MDM2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
HIST2H3D SETDB1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CREBBP HIST4H4 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
DNMT3B HIST1H3A â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
LRIF1 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 21900206 2001699 8089645
DAXX HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10669754 12140263
HDAC1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16287849 26496610 23752268 28514442 26028330
EHMT2 KDM1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26751641 26028330
SUZ12 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26344197 22439931 24457600
HDAC1 REST â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10491605 18806873
MCM5 MCM4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 11248027 22939629 26344197
MDM2 PML â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SUMO2 PML â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25027693 21148299 23543742 17000644 20797634 22155184 21779164 19553342 9452416 17081986 16713569 24637324 21693764 19471022 21252943 15940266 16189514 22578841 20826694 24190887 28851805
DNMT3A HIST1H3J â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CBX5 HIST1H3B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
DAXX UBE2I â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PCNA UBE2I â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BAG6 SGTA â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ATRX HIST1H3A â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CHAF1A PCNA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HIST2H3D HIST3H3 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HIST1H3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CBX8 VIM â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
EHMT2 HIST2H3D â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HIST1H3J HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HDAC2 SIN3B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
H3F3B HIST4H4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HIST1H3J HIST4H4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HIST1H3B HIST4H4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MLF2 AIFM1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 17353931
WIZ EHMT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24981860 26496610 16702210 26344197
EHMT2 WIZ â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HIST3H3 HIST4H4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DAXX MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CHAF1A HIST1H3A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PML TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HDAC1 SP3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CBX5 CHAF1B â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CDK4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
EHMT1 EHMT2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
PCNA DNMT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10888872 23708667 9302295 20613874 26496610 22606318 30301766 12354094 24958773 20940144
CBX5 SUV39H1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CBX5 LRIF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32296183 24981860 23542155 21900206 20562864 27705803
MDM2 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6799761 18566590
SUMO2 DAXX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22578841 19471022 19394292 32786267 16475184 17081986 21252943 21693764 28851805 21383010
HDAC2 DNMT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17967891 23708667 21670149 10888872
EHMT2 EHMT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 21258344 28698370 21430779 27705803 34588438 26028330
WIZ EHMT2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 21258344 28698370 26496610 16702210 27705803 26028330
PML HDAC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18644863 18073335 25812002 11259576
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
DAXX SUMO2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
MCM4 MCM7 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
MCM5 MCM6 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CHAF1A HIST1H3J â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HDAC1 MIER1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HIST1H3A KDM1A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MCM2 MCM5 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CBX5 CHAF1A â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
DAXX TP53 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
JARID2 RBBP4 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CHAF1B PCNA â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AKT1 MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
RBBP4 SIN3A â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
HDAC1 PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14988403 11929879 16189514 16713569
PPARG PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17389773 14764597 19673929
SETDB1 GRB7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DNMT3A H3F3B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CDK4 LUC7L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LUC7L2 SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 AIFM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23506862 16729031
POU5F1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284 20683952
AKT2 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284
SETDB1 ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA7 RBBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA7 CDK4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA7 VIM â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA7 LRIF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA7 BAG6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DAXX ATRX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 23329831 29084956 24981860 26496610 14990586 29937341 31628488 27029610 23222847 23135716 20147399 28875424 15252119 27872097 25416818 28875283 12953102 24651726 31631027 22102817 34162889
EZH2 ATRX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25417162 27634302 9499421
BHLHE40 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15975549 22610404 11879638
BID SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CBX5 MBD1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19498464 16713569 12711603 12697822
CDK4 SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDK4 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HSP90AA1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
VIM CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HSP90AB1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
CDKN1A RBBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A WIZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A LRIF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LEO1 CTR9 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18469135 20305087 27173435 24981860 22532828 26344197 22939629 26496610 20178742 15632063 16024656
POU5F1 DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22795133 30140294
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
DNMT3B TSC22D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DNMT3B PCYT2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EZH2 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EZH2 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
SETDB1 FAM118B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
VIM FAM118B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HSP90AA1 FKBPL â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
HSP90AB1 FKBPL â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
SIN3A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12724404 24981860 14593184 26496610 11102443 17827154 10220385 14647463 9885572 15695521 12398767 26344197 21258344 9804427 16331260 12091390 9150133 11602581 10640275 12920132 9790534 17643391 12943729 19182791 25314079 12374985 28514442 26949739 10444591 11931768 11171972 17956988 12453419 15451426 23752268 11784859 18059533 20585571 9520398 11118440 17962807
MIER1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 18451879 21258344 26496610 23752268 12482978 28514442 16189514
HDAC1 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18381204 21669397
KDM1A HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21937684 34031383 21670149 19703393 24981860 16079794 26344197 21258344 20164337 9804427 32882276 12493763 11102443 12032298 23752268 28667074 26949739 34050636
HMOX2 RBBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HNF4A VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16568083 12750294 19671543
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TK1 LRIF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SMN1 LRIF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TSC22D1 LRIF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAP4K5 SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP63 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11714701 9405685 12374749
TRIM28 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16107876
MDM2 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20571051
MRPL44 SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MZT2B SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PCYT2 SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SP1 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24728382 21360626 16713569 9819401
PML UBE2I â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14992722 18056437 14715247
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
TK1 PSME1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SETDB1 PSME1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SMN1 PSME1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SIN3A RBBP4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9651585 11602581 24981860 21258344 12453419 15451426 9150133 12943729 27705803 9150135 11118440
RBBP4 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RBBP4 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
REST SIN3B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SUMO2 SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TSC22D1 SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SETDB1 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SMN1 WIZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
TP53 SUMO2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
WIZ TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TK1 TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 TRDMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
VIM TSC22D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TSC22D1 WIZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
H3F3B HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3D â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3D â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
MCM3 MCM7 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ARL14EP ATF7IP â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
HDAC2 SUZ12 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
MCM2 MCM3 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CBX5 HIST2H3D â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CDK4 HSP90AB1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
HIST1H3A SETDB1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CREBBP HIST3H3 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CHAF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PROXIMITY ✅ 0.91 0.91 mint 25281560
CBX5 TRIM28 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
H3F3B HIST2H3D â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
HIST1H3A RBBP4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CHAF1B HIST1H3A â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
MCM5 MCM7 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
HIST1H3J RBBP4 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CHAF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24981860
H3C2 CHAF1B â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 7219095 19498464
H3C2 CHAF1B â—¼   PROXIMITY ✅ 0.92 0.92 mint 25281560
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
DAXX PML â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CHAF1B HIST1H3J â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CTR9 CDC73 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
MCM3 MCM6 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
MCM2 MCM4 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CBX5 H3F3B â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
DAXX HIST4H4 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MCM4 MCM6 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
H3F3B MCM2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
MCM3 MCM4 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
MCM2 MCM7 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
EZH2 JARID2 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
HIST2H3D MCM2 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
DNMT3A HIST1H3A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
CDKN1A PCNA â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
MCM6 MCM7 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ATF7IP SETDB1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
EZH2 RBBP4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CHAF1A CHAF1B â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
SUV39H1 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
CBX5 HIST1H3A â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
TRIB3 AKT1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 31844113 12791994 30071535
HDAC1 SIN3B â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CBX5 HIST1H3J â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
ATRX HIST2H3D â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
MCM2 MCM6 â—¼   CORRELATES + 0.96 0.96 CCLE 31978347
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
UBE2I UBE2K â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
HDAC1 DNMT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22274925 10888886 15870198 21670149 17707923 10615135 26794444 17967891 20613874 12473678 17934516 23708667 27593931
RBBP4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 34518534 11302704 11102443 27705803 17827154 10734134 10220385 9885572 10471499 26344197 21258344 12091390 9150133 16713569 11602581 12920132 20127688 9790534 17643391 11470869 19686092 12943729 9150135 28514442 16189514 27068747 10444591 19703393 11171972 15451426 23752268 20585571 9520398 11118440 31435636
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
SIN3A HDAC2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12724404 16254079 12082111 24981860 17827154 22493095 9885572 12398767 26344197 21258344 9804427 12493763 14749338 12091390 12943729 25314079 26949739 12453419 15451426 23752268 9150134 18059533
SUZ12 RBBP4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 27634302 24981860 20075857 22939629 35016035 15225548 24457600 27705803 31281901 28514442
CREBBP PPARG â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DNMT1 PCNA â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ATRX H3F3B â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CREBBP HIST1H3A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CBX5 HIST3H3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDK4 PCNA â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ATRX DAXX â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CDK4 CDKN1A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
MCM5 MCM2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 14681455 23993743 25963833 26344197 11248027 22939629 12614612 15232106 22540012 24207054 16899510 16189514 17296731
MCM5 MCM3 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 23993743 27621311 33961781 25963833 26344197 11248027 22939629 12614612 15232106 25843623 22540012 26264872 28514442 22863883 30108253 16189514 12364596
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
JARID2 SUZ12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RBBP4 SUZ12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DAXX H3F3B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC73 LEO1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC73 CTR9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM2 MCM7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM5 MCM6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM6 MCM7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
TP53 OLFML3 â—¼   KO_UP_REGULATES ✅ + 0.99 0.99 PKG 28854368
MCM2 MCM3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM2 MCM4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM3 MCM4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM3 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM4 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM5 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CTR9 LEO1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
CDKN1A PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 67.0 1.0 Omnipath 23443559 25411249 20606006 8868473 15576034 16474839 25416956 20605778 16510448 18703516 23139781 11302688 11254741 26272819 16616141 21988832 11313979 7780738 17588519 12964161 25502805 10022118 8861913 16189514 26496610 16082198 8861969 17129767 18263614 26186194 22383522 22911014 7915843 7911228 27107012 23223023 17115032 32296183 19895794 18794347 19704162 10873631 9546435 8662825 31515488 21415862 9545252 11350925 12930846
PCNA CHAF1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648606 20112283
PCNA DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17991895 18384127 31235252 28073635 12354094 9302295
DNMT1 H3C2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
KDM1A H3C2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
H3C2 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C2 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
SUV39H1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16409643 19442252 11242053 10949293
SETDB1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21243721 11791185 11252719 11959841
EHMT2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19690169 17194708 22387026
EHMT1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20084102 19010785 20118233
CBX5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16687578 16622419 20871592 20011120 25281560 26527279 19111658 16415788 19498464
SIRT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18337721 16439206 19408108
KDM1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16223729 20210320 18343668 20228790 15620353
EZH2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18022353 15196462
AKT1 MDM2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
TRIB3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 30071535 12791994
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
AKT1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20856200
AKT1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26553800 24492612 27521372 26216216 25949795 21151116 21565170
AKT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11756412 11923280 16697215 20452955 27603133 20398329 18372248 15001356 15808505 10217147 19440234 20138985 12431783 10753973 17855660 19216069 28358423 20214616 11463845 9829964 17570479 17646672 16680151 11231573 15169778 12851486 31575057 25241761 23109003 21933447 10949026 16775416 23886938 26436589 16288292 11715018 16055744 18636226 15023346 9812896 12042314 17680028 24848107 16982699 11779850 10722653 20832730 18570873 20307683 34069970 17052453 15798220
AKT1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22391560 24526064 29864144 34230470 16224021 26517694
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23041284 24497960
AKT1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 11756412 11923280 20856200 20452955 20398329 18332867 19664995 10217147 11154281 19216069 20214616 11463845 19166854 15527798 9829964 17570479 16680151 17646672 12145204 15169778 15140942 25241761 11715018 25209720 17680028 21930127 11504915 29311840 15574337 23397142
AKT2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 11504915 17646672 10217147
AKT2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 21933447 16982699 20452955 9829964 20398329 17646672 10217147
TP53 BHLHE40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22723347 17347673
TP53 BID â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12402042 16151013 18574470
TP53 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15240700 12402042 18431400 15024076
CDKN1A CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 23443559 15169570 18850315 9658399 16962592 15232106 9632134 16189514 8622677 15695403 20102411 8242751 9464540 23007395 7626805 9106657 12383116 30193583 17556661 23543736 8756624
CDK4 SUV39H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10385618 9736735 12006580 10498883
DNMT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21229291 21572997 19056828 16276353 9588214 21868513 23658227
TP63 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15790310 10383130 21480565 12640112 20123734 17404570 16007146 16410722 15965232 12374749 17965458 21093383 23665236 9405685
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
SP3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 10649433 12434298 18850004 7499379 10625687 11064455 23401853 16103879 19584258 12151347 20301197 19197985 15790310 12773551 8995437 10485470 23676218 12379120 18628250 16810128 16533812 23066038 9819384 10321829
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
SP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 9580699 15978937 15557281 11064455 16103879 19584258 20301197 20935676 15961274 15361832 11274368 11842244 15489892 15302882 10212208 12796485 23184467 14529564 12806965 9819384 10321829 10649433 12434298 18270969 18850004 16081043 9183012 21858218 10809237 9618481 16298343 11574165 10362258 11384995 15659839 14744793 10030670 17090534 10733944 19318349 12665570 18202149 17516505 15033443 22001409 17885207 10485470 9553133 15345676 15694838 22427654 17556661 10506225 23066038 15979845 18636159 14527674 24821727 15899840 14755691 12151347 24589735 18210215 23877711 11953011 21311948 15528212 15790310 10878024 22132221 12782287 12773551 8995437 21184768 12379120 17026958 24451377 10601254 8557703 16810128 16533812 7499379 10625687 15389873 16706751 12727210 21325288 16818630 18419600 15041706 23235480 19244234 15694666 23329847 18509005
DNMT3A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20473858 15616584 16131836 24957603
PPARG CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19551868 19103521 19208833 16985067 18509005 15041706 15345676 16091736
EZH2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21572997 21546904 24074410 21629038 22956625
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
SP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17026958 9389648 9618481 17550342 12545156 11013220 15155580 11074002
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
SP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23297421 20096088 9765204 21191649 21464950 12200429 20130956 12169688 15576380 15184875 15713621 18571793
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
DAXX TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12954772 21482821 21134643 16845383 25241761 15364927 16713569 12482984 15339933 23038753
DAXX MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 21134643 16845383 15364927 18566590 23405218 18583933 20195357 23038753
SUZ12 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBBP4 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
EHMT2 DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19308066
RBBP4 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
SUZ12 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
EHMT2 DNMT3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19308066
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
SP1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19540905 15651981 23307400
NLK HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14960582 18855897 11274345 20194509
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
KDM1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17805299 26334721 19381457
MBD1 SETDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15691849 15327775 17066076
MBD1 SETDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15327775 17066076
MCM3 MCM2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM6 MCM2 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 33961781 20211142 22939629 12207017 26496610 30100344 22540012 22863883 25963833 17296731 14681455 26344197 12614612 12694531 25416956 16189514 27173435 26167883 16899510 10567526
MCM4 MCM2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM3 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM3 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM3 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM3 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM4 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM4 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM6 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM6 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
UBE2I MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15195100 12759344 14507915 16713569 12915590
PPARG SAT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14506281 14750214
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
UBE2I PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19692572 15507114 26192107
TRIM28 SETDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11959841
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
SP1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17663720 22227038 3419902 10777586 12771217
UBE2I SP3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15494207 12419227 25114211 18617891 18374648 12356736 15247228 16781829
SUMO2 SP3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 26073453 24782567 25114211 18617891 18374648 12356736 21098080
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
UBE2I TRIM28 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17942393 17079232 25114211 18488044 17298944 18082607
TP53 CLSTN1 â—¼   KO_UP_REGULATES ✅ + 1.23 1.23 PKG 28854368