ATM
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1106300109
22451927
|
ATM
|
SMC1A
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
11877377
5215162
|
ATM
|
H2AX
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16858402
5218840
|
E2F4
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18319725
16135806
|
ATM
|
HERC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20023648
|
NBN
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
MRE11
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
BLM
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
BRCA1
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
RPA1
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
TOP3A
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
RPA3
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0706013104
17686975
|
ATR
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
TP53
|
ATR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
9925639
10435622
|
H2AX
|
ATR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
19146767
11673449
|
ATR
|
SYCP3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
19146767
11673449
|
ATR
|
BRCA1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
23422745
|
ATR
|
POLN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21242293
|
ATR
|
HERC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20023648
|
BLM
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
TOP3A
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
BRCA1
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
NBN
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
MRE11
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
WRN
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATRIP
|
FANCD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20670894
23723247
|
ATRIP
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
TP53
|
ATRIP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
9925639
10435622
|
ATRIP
|
TOPBP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8086392
20871591
|
XRCC5
|
ATRIP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18285803
|
BABAM1
|
BABAM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
NFKB1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11704864
11313951
|
E2F4
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11559537
18319725
|
BCL2
|
XRCC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18313378
|
RELA
|
BCL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11387332
|
XRCC3
|
BLM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
RAD51C
|
BLM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
ESR1
|
BLM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17268063
|
BRCC3
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19202061
0807485106
|
BRCA2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19369211
0811159106
|
SMC1A
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11877377
5215162
|
TP53BP1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15970701
21914189
|
FANCD2
|
BRCA1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
11239454
5213674
|
PIAS4
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21113239
|
BRCA1
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
12700228
|
TP53
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1003689107
20421506
|
SYCP3
|
BRCA2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
22116401
8303438
|
CEP126
|
BRD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
LRIF1
|
BRD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
BRD7
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12489984
6546635
|
BRD7
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
PALB2
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19369211
0811159106
|
E2F4
|
CBX5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12909625
|
AURKA
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
PIN1
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11774038
16713569
|
AURKA
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
RPA2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10882098
10757793
|
NBN
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25558984
22231403
|
CDK2
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25558984
22231403
|
CDK2
|
RPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10882098
10757793
|
CDK2
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10882098
10757793
|
CDK2
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25558984
22231403
|
CDK2
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25558984
22231403
|
RAD54L
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19017809
0807016105
|
XRCC3
|
EME1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
RAD51C
|
EME1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
MRE11
|
FANCD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7906544
19609304
|
H2AX
|
FANCD2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7906544
19609304
|
E2F4
|
FBXO5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18319725
16135806
|
PIN1
|
FBXO5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17875940
|
RNF8
|
HERC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20016603
20023648
|
LRIF1
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
CEP126
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
UBE2D2
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
KAT5
|
CSTF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
KAT5
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
KAT5
|
CEP126
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
KAT5
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10096020
|
CEP126
|
KAT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
LRIF1
|
KAT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
CEP70
|
KAT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
KAT7
|
CEP126
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
KAT7
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
KAT7
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18022353
|
E2F4
|
MKI67
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17531812
|
E2F4
|
MLH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17531812
|
TP53
|
MLH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15781865
|
E2F4
|
MLH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11799067
18319725
|
MSH6
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6548274
9774676
|
MSH3
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6548274
9774676
|
TP53
|
MSH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12209975
|
E2F4
|
MSH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11799067
18319725
|
XRCC3
|
MUS81
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
RAD51C
|
MUS81
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24076221
24831703
|
RAD50
|
NBN
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7114538
19197236
|
UBC
|
NPM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6541703
18259216
|
H2AX
|
PALB2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
22193777
8329239
|
H3C2
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20080577
0913709107
|
PARP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7986053
19779455
|
PARP1
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1429884
|
PARP1
|
AURKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16647857
|
PARP1
|
MRE11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18025084
|
XRCC6
|
PIAS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7986053
19779455
|
RELA
|
PIAS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0701877104
17606919
|
CHD3
|
PIAS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
LRIF1
|
PIAS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
XRCC5
|
PIAS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7986053
19779455
|
PIAS4
|
TCERG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
PIAS4
|
PTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
PIAS4
|
UBE2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
PIAS4
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
PIAS4
|
ZHX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
CEP126
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TP53
|
POLD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11375983
|
POLD1
|
POLD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
10852724
|
E2F4
|
POLD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15574595
18319725
|
WRN
|
POLD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10781066
|
RAD50
|
MRE11
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7114538
19197236
|
RAD52
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216387
12750383
|
CHD3
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
H2AX
|
RAD51
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8149296
21317870
|
E2F4
|
RAD51AP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12909625
|
RAD51B
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216790
14595808
|
RAD51B
|
H2BC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216790
14595808
|
TP53
|
RAD51B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9878257
|
RAD51C
|
TOP3A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
XRCC2
|
RAD51D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10749867
5212428
|
WRN
|
RAD52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216387
12750383
|
WRN
|
RAD52
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5216387
12750383
|
E2F4
|
RAD54L
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15782160
18319725
|
MRE11
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21052091
8081463
|
RBBP8
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
E2F4
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12909625
|
RPA2
|
CEP126
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SMC1A
|
CSTF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SSBP1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19066201
|
TOPBP1
|
TOP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17006541
5219150
|
E2F4
|
TOP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17531812
|
XRCC3
|
TOP3A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
24509834
23509288
|
TOP3A
|
TERF2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6743819
18418389
|
TOPBP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18923429
7296625
|
TOPBP1
|
TP53BP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8086392
20871591
|
TP53
|
E2F4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15574328
24096481
|
AURKA
|
TP53
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
14702041
19121998
|
TP53
|
H3C2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16980608
|
TP53
|
NFKBIA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10698490
12700242
|
TP53
|
HNRNPC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18296503
21317560
|
ING5
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
12750254
|
TP53
|
LGALS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10766163
16713569
|
TP53
|
BARD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14636569
15782130
|
TP53
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7915517
|
TP53BP1
|
UBE2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RELA
|
TP53BP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8910340
8524315
|
TERF2
|
TP53BP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21824286
8202878
|
UBE2U
|
GOLGA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
VCP
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
VCP
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
UBC
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6603858
18588880
|
H3C2
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20080577
0913709107
|
H3C2
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20080577
0913709107
|
XRCC6
|
TNKS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
E2F4
|
XRCC2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17531812
|
E2F4
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15510213
18319725
|
ING5
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
ZHX1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
LRIF1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
CHD3
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
ELP1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
GIT1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
PTN
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
GPRASP2
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
CEP126
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
TCERG1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
KBTBD7
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
BAP1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9528852
19117993
|
FEZ1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
BARD1
|
SETDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
E2F4
|
BARD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17531812
|
E2F4
|
BARD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11799067
18319725
|
UBE2D1
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22842904
21857666
|
LRIF1
|
GPRASP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
GPRASP2
|
CEP126
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
GPRASP2
|
PTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
PIN1
|
HNRNPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
UBB
|
TRAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CEP126
|
KBTBD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
E2F4
|
H3C2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11799066
|
E2F4
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12789259
18319725
|
E2F4
|
AURKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
15033491
|
E2F4
|
CSTF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15782160
18319725
|
E2F4
|
CSTF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18319725
16135806
|
ELP1
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
NFKBIA
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219675
17318178
|
TERF1
|
TNKS
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7987670
20696165
|
TRAF1
|
GOLGA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
CEP126
|
GIT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
LRIF1
|
GIT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
GIT1
|
CHD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
GIT1
|
TERF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
UBC
|
USP15
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
FEZ1
|
CSTF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
CEP126
|
CSTF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
ELP1
|
CSTF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
CHD3
|
CSTF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TCERG1
|
CHD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
PTN
|
CHD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
ZHX1
|
CHD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
LRIF1
|
CHD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
CHD3
|
PTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TCERG1
|
SETDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
ING5
|
CEP126
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
ZHX1
|
TERF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
CEP126
|
FEZ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
FEZ1
|
PTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
FEZ1
|
CEP126
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
FEZ1
|
LRIF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
CEP126
|
LRIF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
LRIF1
|
SETDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
BLM
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
ATM
|
RBBP8
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.8
|
0.8
|
Signor
|
10910365
|
RAD50
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
18854157
|
ATM
|
RAD50
|
â—¼ PHOSPHORYLATION
|
|
|
0.8
|
0.8
|
Signor
|
17570479
|
ATM
|
WRN
|
â—¼ PHOSPHORYLATION
|
|
|
0.8
|
0.8
|
Signor
|
10608806
|
RAD50
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
10426999
|
BABAM1
|
TNKS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
ATM
|
COM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
23468639
10608806
10910365
22544744
|
ESR1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
1204073
5215931
11244506
|
H2AX
|
BRCA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
18406329
20936109
|
H2AX
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
6805208
18583988
|
MRE11
|
H2AX
|
â—¼ COLOCALIZATION
|
✅
|
|
0.81
|
0.81
|
mint
|
22157895
8303386
|
ESR1
|
UBE3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
9891052
16772533
29388081
16314411
31329371
22865929
|
H31
|
FACD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
29760279
22828868
|
CBX1
|
CBX3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
810.0
|
0.81
|
STRING
|
36370105
|
BRD7
|
SMARCB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
CCNE1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
MDC1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
BLM
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
24239288
|
MDC1
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22990118
29656893
|
CBX1
|
H2A1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21888893
27248496
|
MDC1
|
CBX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
22990118
|
CBX5
|
BAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27107012
34591877
|
CBX5
|
AURKB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20231385
20562864
|
CDK2
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
21319273
|
CDK2
|
E2F4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25852190
|
HERC2
|
EME1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25476789
29426014
|
MDC1
|
BRE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22990118
29656893
|
XRCC6
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22863883
21075794
|
H31
|
MSH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
29568061
|
ESR1
|
MSH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16260778
31527615
|
MRE11
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
24981860
|
UIMC1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
25252691
|
PARP1
|
TOP2B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
16794079
|
H2AX
|
RAD50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16377563
19234442
31501894
15201865
10959836
18583988
|
H31
|
RAD50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26527279
29568061
|
RAD51
|
XRCC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20189471
15065660
15123651
19327148
|
H31
|
SMC1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26527279
29568061
|
FACD2
|
TOP3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25659033
31180492
|
CHD3
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28977666
30585729
|
XRCC6
|
BARD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
15782130
22990118
|
H31
|
BARD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25634209
25281560
|
NR1H3
|
BARD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24009820
19164445
|
BARD1
|
AURKB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19176389
22350409
|
BARD1
|
LEG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24755837
22990118
|
SKP2
|
UBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
UBB
|
UBE3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25416956
22645313
|
AURKB
|
H31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
18477699
34079125
10949293
11756469
21397507
|
FEZ1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ESR1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21761334
31527615
|
ESR1
|
PARN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23403292
31527615
|
ESR1
|
LEG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23403292
31527615
|
ESR1
|
H31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23403292
31527615
|
BLM
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
ATM
|
MDC1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
12607003
|
ATR
|
MRE11A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
825.0
|
0.82
|
STRING
|
36370105
|
MSH3
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HuRI
|
32296183
|
HIST1H3A
|
NPM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
RAD51B
|
RAD51D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
HIST1H3A
|
ING5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
827.0
|
0.82
|
STRING
|
36370105
|
ATR
|
WRN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10608806
22159421
17118963
|
BRCA1
|
TERF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34112789
19797051
29656893
|
BRCA1
|
TERF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34112789
25184681
19797051
29656893
|
BRCA1
|
CDK9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22990118
28278048
|
BRCA2
|
SEM1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
22293751
8384352
|
H3C2
|
CBX1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
16415788
5218238
|
CBX1
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
16415788
5218238
|
CCNE1
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9053846
9891079
1388288
|
BARD1
|
LARP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22990118
32726637
|
BARD1
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12611903
29656893
|
RAD50
|
COM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31636387
25558984
16391231
27940557
|
RPA2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11953755
31527615
|
H31
|
TOP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34079125
29568061
20504901
|
H2AX
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21679440
18406329
20085707
|
PCNA
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
FACD2
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19609304
17304220
31180492
|
BARD1
|
COM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
20351172
21335604
10764811
25252691
16391231
|
UBB
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
UBA1
|
UBE2E2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
BRCA1
|
RBBP8
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
16818604
|
RBBP8
|
BRCA1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
24832651
|
H2AFX
|
RNF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
ATM
|
NBN
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
10802669
|
BRCA1
|
FANCD2
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
12485996
|
HERC2
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ESR1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
PCNA
|
POLN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
HIST1H2AB
|
HIST1H2BB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
BRCA1
|
UBE2E3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
BRCA1
|
UBE2E2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
BRCA1
|
UBE2E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
BRCA1
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
RAD52
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
BRCA1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
PIN1
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16713569
11988841
11326318
|
BLM
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
MSH2
|
BLM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10783165
15064730
|
MSH6
|
BLM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10783165
15064730
|
BLM
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15364958
29523790
|
BLM
|
FACD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25135477
31180492
15257300
|
PARP1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
34079125
25252691
26831064
|
BRCA1
|
H2A1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
34321665
25131202
25355358
32092106
29367421
33589814
|
CBX3
|
LRIF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
24981860
|
CDK9
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
CDK9
|
SKP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11689688
12861003
|
KAT7
|
ING5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
17954561
27270040
16387653
33961781
24981860
|
MDC1
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28973861
16186822
|
NBN
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
17121922
10783165
|
XRCC5
|
TOP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28415827
21679440
|
PCNA
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12171929
11239001
24695737
|
H31
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
26527279
33029857
|
BARD1
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12485996
11927591
|
H2AX
|
H31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
23319141
31045206
20587414
20224553
29229926
16622419
26095369
|
BARD1
|
FANCJ
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
27399284
17664283
16391231
25252691
20451671
18628483
|
ESR1
|
MED17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21182203
11867769
|
CSTF1
|
CSTF3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11459828
10669729
26344197
|
RAD51
|
RAD51C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
TOP1
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
POLR2A
|
SMARCB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
BARD1
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
UBB
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
HIST1H2AB
|
HIST1H3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
HIST1H3A
|
HIST2H2BE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
CHD3
|
HIST1H3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
TP53BP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
BARD1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
RAD50
|
BLM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
29523790
25084169
10783165
|
BLM
|
TOP3A
|
â—¼ COLOCALIZATION
|
✅
|
|
0.85
|
0.85
|
mint
|
20711169
8048867
|
BRCA1
|
WRN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16714450
24709898
29656893
|
BARD1
|
CBX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
30874560
32347575
25634209
|
H3C2
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
20871592
8087215
|
CBX5
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
16415788
5218238
|
H3C2
|
CBX5
|
â—¼ PROXIMITY
|
✅
|
|
0.85
|
0.85
|
mint
|
25281560
|
UIMC1
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
19615732
23264621
|
CDK1
|
SKP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
26496610
33422522
33961781
26186194
32707033
|
RNF8
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18001825
23115235
26869104
|
NBN
|
COM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18171670
27561354
23468639
26387952
25558984
27940557
|
TP53
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
12397362
5215850
|
BARD1
|
UBA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12485996
12431996
11927591
12438698
11278247
12887909
15184379
|
XRCC5
|
WRN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
10783163
5212534
|
WRN
|
XRCC5
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
10783163
5212534
|
H2AX
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
23145133
15613478
33961781
18406329
20224553
|
PCNA
|
FACD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25893307
19704162
31180492
|
BARD1
|
H2A1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
34321663
33589814
|
BARD1
|
UB2D1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12485996
19916563
11927591
12890688
14636569
12438698
11278247
12887909
15184379
24507701
|
H31
|
CHD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16728976
11850410
34079125
29020631
29568061
25533843
|
FANCJ
|
FACD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25070891
26336824
31180492
|
TP53
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
RPA1
|
RPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
MDC1
|
TOPBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
855.0
|
0.85
|
STRING
|
36370105
|
UBE2D3
|
UBE3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
UBB
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
BRCA1
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
NBN
|
BLM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
29523790
10783165
|
BRCA1
|
ABRAXAS1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
34591612
|
AURKA
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22110403
14990569
26831064
|
CBX1
|
CHD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28977666
21888893
|
CBX3
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
21888893
|
CDK2
|
TP53
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
24173284
|
FANCD2
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
MLH1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15225546
32814904
28439008
|
H2AX
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
6805208
18583988
|
H2AX
|
NBN
|
â—¼ COLOCALIZATION
|
✅
|
|
0.86
|
0.86
|
mint
|
22565321
8391733
|
NBN
|
H2AX
|
â—¼ COLOCALIZATION
|
✅
|
|
0.86
|
0.86
|
mint
|
22157895
8303386
|
PCNA
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20129057
20302655
12930846
21690293
20303835
|
WRN
|
XRCC6
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.86
|
0.86
|
mint
|
10783163
5212534
|
CSTF2
|
CSTF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10669729
26344197
|
RNF8
|
UBE2D3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
BRCA1
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
PCNA
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
BLM
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
MRE11A
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
BAP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
TP53
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
ATR
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CDK1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
UBA1
|
UBE2W
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
ATM
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16858402
27918549
22184063
9488723
32518374
20081839
18344987
21676867
22451927
21704408
11571274
11893489
26095369
|
BRCA1
|
MSH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
14578343
11498787
|
BRCA2
|
XRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26496610
18212739
24141787
20450923
16621732
|
BRCC3
|
BARD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
14636569
17664283
17525341
|
BAP1
|
CBX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32509391
19615732
34591877
29686263
|
LRIF1
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
21900206
2001699
8089645
|
RNF8
|
HERC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26503038
20023648
25305019
22814251
22508508
|
MDC1
|
FACD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
29656893
31180492
12607005
|
BARD1
|
MSH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16391231
11498787
|
PALB2
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26833090
22193777
20332121
28319063
22331464
20871616
24141787
33961781
19584259
28240985
23585894
20871615
29499138
25016020
28398198
16793542
|
PARP1
|
PIAS4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19779455
20696768
|
PARP1
|
NFKB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16204234
11590148
25609649
16799643
|
FACD2
|
RAD50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19609304
31180492
|
H2AX
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31009828
30560944
21317870
28796254
29499138
28190324
10959836
|
FACD2
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25893307
27694619
30818369
12239151
|
RAD51
|
WRN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17118963
18562274
|
ESR1
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17311814
31527615
|
WRN
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20802463
15733840
|
TERF2
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21824286
21044950
22157895
|
BARD1
|
FACD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12887909
31180492
|
TRAF1
|
UBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
14743216
33961781
|
AURKA
|
NFKB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
27609421
33961781
25609649
26186194
|
ESR1
|
FOXK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31527615
25740706
|
COM1
|
FACD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24556218
31180492
24794430
24794434
|
UB2D1
|
UBE3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16189514
19240029
17426036
16713569
14517261
27903893
9450543
9575161
10066826
33961781
15001357
8576257
8090726
24743594
|
ATRIP
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BCL3
|
NFKB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MRE11A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CBX3
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
RAD52
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
KAT5
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
RAD50
|
TERF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
BRE
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
BARD1
|
CSTF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
MRE11A
|
TERF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ATR
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BABAM1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BLM
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
TUBG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
TOPBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
RAD51
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
HSPA4
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ATM
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BRIP1
|
TOPBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
AURKA
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BAP1
|
FOXK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ATR
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
NPM1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
PCNA
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
PIN1
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
TERF2
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
ATM
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10608806
10783165
15758953
|
BARD1
|
BCL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16713569
10362352
|
FANCJ
|
BLM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24895130
21240188
|
MRE11
|
BLM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
29523790
28506294
10783165
|
BRCA1
|
BLM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
25084169
10783165
26831064
29656893
|
BRCA1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
SMC1A
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11877377
25184681
16713569
26831064
|
BRCA1
|
MED17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12154023
11504724
15208681
|
BRCA1
|
CSTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11257228
10477523
|
BRCA1
|
UBE2N
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19712108
21965653
17873885
|
BRCA1
|
UBA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12485996
11927591
14638690
12438698
26831064
11278247
12887909
15184379
|
BRCA1
|
CBX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
23074186
25634209
25184681
|
BRCA1
|
UBE2K
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19712108
23246971
21965653
17873885
|
BRCA1
|
UBE2W
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
25436519
19712108
21965653
17873885
|
BRCA2
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
14636569
17664283
|
BRD7
|
H31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12489984
26527279
29568061
|
BRIP1
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
UBE3A
|
HERC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21493713
30257870
30279242
22645313
25476789
29426014
|
WRN
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
14734561
14596914
|
H31
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20080577
28190768
33961781
32937373
34079125
29568061
20504901
|
POLD2
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
31449058
|
RAD51
|
XRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15065660
17302439
11842113
28864920
9660962
|
BARD1
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19615732
17525341
|
UIMC1
|
BRE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21282113
19261749
19261746
19261748
17525341
20656689
19015238
19615732
|
H2AX
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16377563
19234442
31501894
22157895
15201865
12419185
18583988
|
COM1
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
27561354
33723063
25349192
21052091
26807646
22231403
26387952
31636387
25558984
|
MRE11
|
FACD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19609304
31180492
12447395
|
AURKA
|
TACC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15064709
14602875
14603251
|
ATM
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
UBC
|
USP15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
HIST1H2BB
|
HIST1H3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
HIST2H2AC
|
HIST2H2BE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
ATR
|
ATRIP
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.88
|
0.88
|
Signor
|
15451423
|
CDK9
|
LARP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
ESR1
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
MDC1
|
MRE11A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
NBN
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
PARP1
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
RAD51
|
RAD54L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
MRE11A
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
BRCA2
|
FANCD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
BARD1
|
UBE2D3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
NFKBIA
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
H2AFX
|
MRE11A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
BCL2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
RAD51C
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
ATM
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
POLD1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
RPA1
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
UBE2D2
|
UBE3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
HERC2
|
UBE3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
RAD51B
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
PCNA
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
BARD1
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
H2AFX
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
UBC
|
USP25
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
MDC1
|
ATM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29656893
14519663
28943310
12607005
26734725
18006705
|
ATM
|
FACD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14499622
12086603
|
ATM
|
SMC1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11877377
11877376
|
ATR
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17526493
10608806
15758953
23368512
|
BRCA1
|
ATRIP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17616665
24073851
29656893
|
NBN
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10426999
18171670
19244116
12124328
10783165
25659039
25184681
25939603
11504724
29656893
|
CSTF1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29180510
11257228
11278247
|
MDC1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21622030
19766185
15569676
12611903
17525332
12607005
29656893
|
BAP1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9528852
23850490
16713569
|
E2F4
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21102443
16713569
9244350
|
UIMC1
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18077395
19305427
21282113
19261749
19261746
23264621
19261748
19202061
17525341
20656689
19015238
19615732
|
MLH1
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
5220047
17581638
|
CBX1
|
LRIF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
27705803
24981860
23542155
16169070
|
CBX3
|
CHD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
34079125
28977666
21888893
|
CBX5
|
LRIF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21900206
32296183
23542155
27705803
24981860
20562864
|
UIMC1
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21622030
22990118
21857162
24240613
29656893
|
XRCC6
|
MSH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22863883
30585729
21075794
|
TERF2
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22939629
19287395
10888888
|
FACD2
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19609304
31180492
12447395
|
H2AX
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16377563
20000738
27728808
33961781
28796254
18406329
28242625
16522924
20085707
|
BARD1
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14636569
32347575
28976962
25252691
|
RAD52
|
WRN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17118963
12750383
|
UBE2N
|
RNF8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31048496
25909880
29523790
19549727
22589545
21706008
24732096
18678647
28244869
20023648
21911360
16215985
26285145
23255131
27909234
22814251
31792955
|
WRN
|
TERF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12181313
18212065
|
WRN
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12177300
11328876
26496610
14734561
12937274
21679440
10880505
10783163
|
H31
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20080577
34079125
26527279
29568061
20504901
|
H31
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20080577
29568061
21187428
33961781
34079125
26527279
25281560
20504901
|
MRE11
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
30585729
10508516
26344197
|
XRCC6
|
TERF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21044950
26496610
10984620
|
TERF2
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22939629
19287395
10888888
18212065
|
SKP2
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11237742
22959436
10790373
|
UBC
|
UBE2D3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
MRE11A
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
H2AFY
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
RAD51
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
UBA1
|
UBE2D3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
H2AFX
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
BLM
|
RAD52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
MDC1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
TERF1
|
TNKS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
UBE2D2
|
UBE2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
RPA1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
TERF1
|
ATM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18160036
11375976
15314656
|
ATM
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11114888
11278964
29656893
10783165
11016625
10866324
10550055
15713674
18344987
10608806
17478428
|
ATM
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24800743
10783165
25088203
11252893
30952868
10608806
17507690
22464731
25895060
10839545
15758953
10839544
|
ATM
|
BLM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29523790
10783165
12034743
|
TP53
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9843217
9733515
9733514
|
KAT5
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16141325
|
ATRIP
|
ATR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19097996
28514442
19889979
17384638
15758953
14724280
15451423
23144622
26854234
21285353
18344416
20847938
20616048
15743907
14657349
11721054
15538388
17686975
18162465
17526493
33961781
15210935
18283122
|
ATR
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11114888
11278964
23901102
29656893
16713569
11016625
10608806
17478428
|
ATR
|
UIMC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18519686
|
TOPBP1
|
ATRIP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20068082
18769153
|
BRCA1
|
BACH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17664283
15208681
16713569
19369211
17525340
15125843
15242590
16391231
25252691
11301010
11877378
|
KAT5
|
BCL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
15829968
10362352
|
TP53
|
BCL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12808109
24189068
|
BLM
|
TOP3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12724401
20360068
11406610
23509288
24239288
10734115
26496610
30279242
11470874
15775963
10825162
20711169
|
BLM
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12724401
10783165
11691925
11325959
21466675
11470874
19015241
|
BLM
|
TERF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12181313
19329795
15229185
|
BRIP1
|
BLM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21240188
|
BRCA1
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
H2AX
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12485996
34321665
19766185
18001824
31501894
11927591
18344987
20681793
26095369
18001825
29499138
19805520
26121674
10959836
12419185
|
PALB2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19369211
25184681
19584259
23038782
29656893
26649820
30337689
28319063
28089683
28398198
22193777
19268590
22331464
34408138
23585894
25016020
19553677
24085845
25652403
|
ESR1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
1244506
11782371
15674350
29367421
27977889
17392432
16860316
10334989
16260778
11244506
16061635
12400015
17505062
20060929
25499220
16713569
31527615
11493692
|
FACD2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
12887909
25652403
14499622
11239454
31180492
29656893
|
BRE
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14636569
22990118
25184681
29656893
|
RAD51
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31270457
31009828
11498787
16713569
19766185
25659039
19369211
25499220
9774970
28319063
17302439
9008167
14636569
28976962
24085845
34408138
29656893
|
MLH1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10783165
17148452
25184681
16786532
21240188
29656893
|
BRCA2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11477095
17664283
16713569
21135251
19369211
9774970
25184681
14636569
24085845
34408138
25652403
14499622
29656893
|
CDK2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31270457
16713569
10373534
9244350
8764100
|
FANCJ
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17664283
19369211
17525340
30257991
25184681
22792074
17525341
28911102
23530059
15125843
26831064
14576433
29656893
18717574
15133502
15208681
18285836
20159462
25252691
14578343
21240188
11877378
18628483
28398198
19452558
17596542
17581638
14576432
23157317
17525342
27399284
16713569
20173781
24573678
22032289
20681793
15242590
16391231
11301010
|
BRCA1
|
MSH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16260778
25184681
11498787
10783165
|
BRCA1
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10426999
10783165
17349954
25184681
23530059
16391231
11353843
24413181
11504724
29656893
|
BRCA1
|
UB2D1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12485996
19916563
16403807
27312108
11927591
12732733
14638690
12438698
14636569
12890688
19712108
11278247
12887909
15184379
24507701
|
BRCA1
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11498787
16713569
10783165
15886699
16260778
|
BRCA1
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19305427
17664283
19202061
22990118
25184681
14636569
25252691
29656893
|
BRCA1
|
COM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18171670
19369211
17525340
30257991
25184681
21908405
16818604
29656893
26446986
18285836
20351172
25659039
11689934
9738006
10910365
15485915
10764811
25252691
31636387
14578343
29513652
28398198
19452558
10196224
34408138
22231403
17525342
27454289
11739404
16843262
28132842
31932421
24085845
9811458
25310973
26387952
23416467
|
BRCA1
|
UIMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21622030
17525340
25184681
17525341
17643121
29656893
19305427
26446986
25252691
26027929
28569838
19766185
19261748
34408138
29499138
19615732
17525342
17621610
31932421
24085845
|
BRCA1
|
RAD50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10426999
18171670
12124328
16713569
10783165
25084169
25184681
16260778
16391231
11504724
29656893
|
BRCA1
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16713569
9774970
9008167
|
BRCA1
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17873885
11320250
14636569
|
PALB2
|
BRCA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20332121
19369211
24485656
17200672
24141787
19584259
28240985
23038782
16793542
26833090
26649820
28319063
24835992
30410870
17420451
28398198
22193777
19268590
21466675
22331464
19609323
26990772
23585894
25016020
19553677
28765325
33961781
20871615
22293751
|
BRCA2
|
BARD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14636569
17664283
16391231
19176389
|
BRCA2
|
FACD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19861535
28684355
18212739
20450923
15115758
15199141
18263878
31180492
|
NFKB1
|
BRCA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10961992
|
RELA
|
BRCA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10961992
|
BRE
|
BRCC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21282113
19261749
19261746
30755420
19261748
17353931
20656689
14636569
33961781
20032457
19615732
|
RPA3
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
CBX1
|
CBX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17314413
11336697
16713569
27705803
33961781
21888893
24981860
34079125
|
CBX5
|
CBX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17314413
11336697
16713569
20850016
27705803
20231385
33961781
21888893
24981860
15306854
34079125
20562864
19498464
|
CBX3
|
LRIF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
23542155
27705803
33961781
21888893
24981860
34079125
|
CDK1
|
FOXK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20810654
|
SKP2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16189514
9858587
9636170
25852190
23455922
10559858
19270695
26496610
23602568
16979657
10386600
19686743
15355997
20160477
18604603
22770219
33422522
33961781
26186194
7553852
|
PCNA
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10930425
|
CDK2
|
BARD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15855157
15665273
31270457
|
CDK9
|
LARP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
26659056
32707033
17643375
20562857
18281698
26725010
33961781
26186194
23602568
27684187
23455922
18483487
24367103
29845934
|
EME1
|
MUS81
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19596236
28514442
16189514
25224045
27354282
24733841
25319828
21962513
29738624
19017809
33961781
28575661
14617801
12686547
12721304
17289582
19363487
18413719
|
RPA2
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
ESR1
|
KAT5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31527615
17418098
16260778
22081016
11591700
|
KAT7
|
H3C2
|
â—¼ ACETYLATION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
18381289
18623064
19187765
|
RNF8
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25512560
28943310
24240613
18001825
26734725
18001824
18006705
|
MDC1
|
RAD50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
30179224
29656893
14519663
12607005
12607003
18583988
|
MDC1
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21622030
16377563
19234442
28242625
32518374
20159462
21676867
12475977
14519663
15201865
12607005
21293379
30598506
18001825
29499138
26734725
18001824
18583988
|
MDC1
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15377652
30179224
12607003
18678890
29656893
27590578
25064736
20460517
19804756
23115235
14519663
15201865
12607005
20224574
18001824
18583988
|
MDC1
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
30179224
29656893
20081839
14519663
12607005
12607003
18583988
|
MLH1
|
FANCJ
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23585563
20173781
24573678
24966277
22792074
17581638
20978114
25502805
22968820
33961781
16391231
17148452
|
TP53
|
MLH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18431400
15781865
|
TP53
|
MSH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11350971
8630028
|
NBN
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
NBN
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
NBN
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11110662
18583988
15733840
16377563
31501894
20081839
23145133
22157895
22941933
21676867
16932743
15201865
18001825
18001824
12419185
|
NBN
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
30179224
11238951
17612497
22941933
23530059
15758953
11062235
10426999
19244116
10783165
18458108
21884979
22464731
33558481
24413181
26455393
12447395
12679336
28369484
22078559
34038735
22231403
12419185
22939629
34348893
17526493
12861053
17500065
12750284
9705271
28363998
30440001
24981860
19270065
12607003
15734743
|
PARP1
|
PARG
|
â—¼ DE_ADP_RIBOSYLATION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17548475
21398629
15607977
|
TOP1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
34079125
15247263
15848144
|
PARP1
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24140708
16490787
16794079
14734561
33961781
30585729
34079125
10400681
17283121
|
PARP1
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24140708
16490787
21575865
16794079
14734561
21679440
34079125
10400681
17283121
20085707
|
PARP1
|
PIAS4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19779455
20932475
|
PIAS4
|
RPA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20016603
|
POLD2
|
POLD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16000169
10852724
16510448
|
RPA3
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
TERF2
|
RAD50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19287395
15100233
10888888
18212065
22939629
|
RPA1
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RBBP8
|
MRE11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17965729
21052091
|
RPA1
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22902628
23042605
23042607
|
RPA1
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22902628
23042605
23042607
|
TP53
|
POLD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19861536
|
TP53
|
WRN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9774636
11427532
|
TP53
|
KBTBD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16980608
|
UBA1
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17597759
24816145
21209336
|
UBE2N
|
HERC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16112642
16428300
16122702
|
UBE2N
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17709392
18077395
|
WRN
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
10871373
12750383
12633936
20600238
|
WRN
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
12177300
11328876
26496610
14734561
33961781
10880505
10783163
30585729
|
XRCC6
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15910003
19177010
28514442
28035050
14681455
10750018
17159921
25574025
17308091
10984620
11196700
32296183
7699019
33005030
15367688
12145306
19118032
10446239
26496610
19906305
26774286
10207052
21454661
18809223
9488450
26446488
15520013
30021884
22939629
17283121
10219089
10757784
21070772
11493912
21172662
15023334
22863883
22451927
21679440
24981860
10783163
33961781
30585729
26344197
|
E2F4
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17671431
|
BARD1
|
CSTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11257228
20379136
10477523
|
BARD1
|
CSTF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28634376
27591253
29180510
11257228
20379136
10477523
18842000
|
ESR1
|
BARD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17275994
|
TNKS
|
AXIN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
19125156
19759537
22440753
|
PIN1
|
LRIF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RELA
|
PIN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19458071
19668231
16950761
|
AURKA
|
PIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23970419
|
E2F4
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17531812
12789259
20946668
|
AURKA
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23993973
17308110
|
ESR1
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21761347
21761334
18497064
|
H3C2
|
ING5
|
â—¼ ACETYLATION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
18381289
18623064
19187765
|
BAP1
|
FOXK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25451922
20805357
27773593
27705803
34591877
33961781
25609649
19815555
19615732
24748658
|
H31
|
H2A1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20080577
27248496
31142837
33961781
20498094
21743476
23415232
|
BRCA1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
BRCA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
MRE11A
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
RNF8
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
PARP1
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
TOP1
|
TOP2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
UBE2D1
|
UBE3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
H2AFX
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
PALB2
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
ATR
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
ATR
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
UBB
|
UBE2D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
HIST1H3A
|
SETDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
PALB2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
8329239
22193777
|
PALB2
|
BRCA1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
28319063
|
BRCA1
|
PALB2
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
8329239
22193777
|
LARP7
|
CDK9
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
6613869
18483487
|
MSH2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
RAD51C
|
RAD51B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
34591612
|
UBE2N
|
UBA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
31638574
14517261
18678647
25527291
27173435
30097011
33619271
27182664
29537486
|
ATM
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
UBA1
|
UBE2E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
E2F4
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
CDK2
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
WRN
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
CSTF1
|
CSTF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
ATM
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
MSH3
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
ATM
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
BRCA1
|
UBE2D3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
POLD2
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
MDC1
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
MLH1
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
UBA1
|
UBE2L3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
H2AX
|
KAT5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
23777805
20224553
18406329
|
RPA3
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
24126761
|
TP53
|
UBE3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
UBA1
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
CCNE1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
CDK9
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
RPA1
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
RAD51C
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
RAD51D
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
UBA1
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
BLM
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
UBE2L3
|
UBE3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
POLD3
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
RAD51
|
RAD54B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
BLM
|
MRE11A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
BLM
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
H2AFX
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
UBC
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
NBN
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
RAD52
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
MRE11A
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
ING5
|
KAT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
RAD51C
|
RAD51D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
H2AFY
|
HIST1H3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
MSH6
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
12799449
30770470
10783165
10748159
|
MLH1
|
MSH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
29892012
25416956
17148452
|
PCNA
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
15225546
12171929
16189514
8858149
|
RPA1
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
TOP3A
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
BRCA1
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
BLM
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
FANCD2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
UBA1
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
WRN
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
UBA1
|
UBE2D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
ATR
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
MSH2
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
25241761
10783165
31843968
30770470
12799449
10748159
|
RAD51
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
RAD51B
|
RAD51C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
MDC1
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
MLH1
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
CSTF2
|
CSTF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
UBB
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
CSTF1
|
CSTF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
CBX5
|
HIST1H3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
PCNA
|
TOP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
UBA1
|
UBE2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
UBB
|
UBE2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
BLM
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
POLR2A
|
SMARCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
MRE11A
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
ATR
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
14657349
21285353
33005030
|
H31
|
CBX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
24576085
16415788
34133717
26527279
24981860
20011120
15136563
33097091
|
CBX5
|
H31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
16415788
26157143
16687578
26527279
33961781
24981860
19783980
34079125
20011120
16622419
25281560
19498464
|
PCNA
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12361598
28514442
26496610
29510343
9545286
33961781
26186194
7903056
21319273
10930425
|
CDK2
|
CCNE1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.96
|
0.96
|
Signor
|
19561641
|
RPA1
|
RPA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
24207024
22939629
26399832
26496610
24981860
16514417
19214185
26344197
|
UBC
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17568776
5220017
|
XRCC6
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5219440
17159921
|
XRCC5
|
XRCC6
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.96
|
0.96
|
mint
|
10783163
5212534
|
CSTF2
|
CSTF3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16189514
16713569
22939629
10669729
26344197
|
H2AFX
|
HIST1H3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
ATM
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
CBX3
|
HIST1H3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
CBX1
|
HIST1H3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
UBC
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
NFKB1
|
BCL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
20558726
10362352
17962807
20547759
8428580
10469655
14678988
20800578
15829968
30833792
|
BLM
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
19671661
29523790
12606585
17984114
11309417
11278509
19956565
18562274
15064730
|
BARD1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12431996
17525341
29367421
27977889
19916563
12732733
10477523
20060929
23680151
8944023
22110403
12951069
23086937
14638690
27239795
29355525
9788437
11925436
11257228
24289923
14647430
19176389
15184379
9738006
16403807
29180510
11278247
33589814
15265711
15159397
34408138
16713569
19117993
20681793
16391231
11301010
16489000
23416467
17664283
15569676
29858377
19369211
18493658
29656893
20351172
28398198
12485996
32347575
19766185
14636569
10026184
12700228
31270457
11573085
11526114
24085845
25823446
33961781
32092106
18936166
28514442
20215511
25184681
26490435
28948225
12890688
12438698
28262780
26831064
9342365
10635334
15855157
11504724
11773071
25252691
9798686
26350354
21901007
24695549
12887909
17873885
11498787
27454289
11927591
24981860
25652403
25634209
|
PALB2
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
19609323
7262167
|
BRCA2
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9405383
19875419
23935068
14580352
9774970
15937124
11239456
21076401
10551859
16513631
21601571
25585578
12815053
16793542
11477095
26833090
21670257
26145171
18264088
15713648
9811893
12941707
25282148
20729832
26387543
24835992
18429819
15800651
17515903
21399666
18317453
22116401
11313963
33476590
14636569
15897881
15800615
10373512
9523196
9126738
27941124
17541404
12442171
9560268
20729859
12619154
16914443
28765325
17515904
31113933
28757209
15065660
19303847
28168276
19628690
12606939
24013206
24981860
20871615
15671039
22293751
21789034
|
CBX1
|
CBX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
17314413
11336697
27705803
24981860
21888893
20562864
|
CBX1
|
H31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11882902
16415788
15960974
11242053
15100215
26527279
16622419
29568061
15136563
|
NBN
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
20224574
7891431
|
H2AX
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
6805208
18583988
|
MSH3
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16025128
8942985
10029069
8805365
14657349
33961781
9774676
22939629
22179786
19377479
|
MSH3
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12171929
25416956
32296183
11274057
11005803
|
MSH6
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12171929
16189514
15225546
24958773
21725088
26496610
11005803
11274057
22939629
22232658
26344197
|
RAD50
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
30179224
12607003
12124328
11238951
17612497
22941933
23530059
24651726
15758953
11062235
10426999
10783165
22464731
19197236
12447395
12679336
26215093
22939629
34348893
17526493
17500065
9705271
16391231
30440001
24981860
26344197
15734743
|
RAD52
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28551686
10448035
8550550
10212258
9837724
20190268
17118963
9826763
12750383
10666456
15766559
19338310
|
ATM
|
MRE11A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
UBXN1
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
NBN
|
TERF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
RPA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
BRCC3
|
BRE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
MSH6
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
UBC
|
UBE2D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
BABAM1
|
BRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
BRIP1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5220047
17581638
|
RAD51
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5219969
17541404
|
SMARCA2
|
SMARCB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
BLM
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
BRCA1
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
BRCA1
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
BRCA2
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
RAD52
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
RPA1
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
TP53
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
UBC
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
NFKB1
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
CDK2
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
28137908
16431923
29439025
9891079
18559665
33854235
11940657
15004009
17431037
17361108
33854239
14681455
17254967
8867812
23853094
10827081
10330164
8662825
25852190
15557281
9192873
23455922
21092281
14536078
21372285
21241890
19631451
16223725
26496610
1388288
9716181
9472014
15980415
14701826
23602568
8978686
11433299
11132966
24771265
12839982
20587660
19470470
10359664
15514162
17970072
9840943
25728284
9660939
8647086
24358021
7799941
12529437
8756624
33961781
15670215
26186194
20837141
12800980
|
MSH6
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
19377479
25241761
10783165
8942985
9428522
10029069
26496610
10856833
14657349
10748159
33961781
9774676
22939629
26344197
15064730
|
RAD50
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
30179224
12607003
30733337
10888888
23530059
24651726
11062235
17694070
10783165
31501894
33558481
19197236
24413181
26455393
10508516
16163361
28369484
26215093
34038735
8756642
22939629
34348893
17500065
12750284
9705271
16391231
27173435
28363998
24981860
19270065
11504724
26344197
15734743
|
UBA1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
BLM
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
POLR1A
|
POLR2H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
BABAM1
|
BRE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
BRCA1
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
MRE11A
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
UBC
|
UBE2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
POLD1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
TOPBP1
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
POLD2
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RPA1
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
BARD1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
UBC
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
XRCC5
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NFKBIA
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
POLR2A
|
POLR2H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
WRN
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12202749
12607003
15140942
15211575
15385537
15459660
15498778
15964794
16163361
16449207
17055429
17116323
17303408
17965729
18087292
18171986
18398454
18524993
18558713
18584027
18809224
19202191
19362533
19490890
19654615
19772495
19793801
19892829
20027199
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
9721205
|
XRCC6
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
H2AX
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11934988
15279782
12792649
11893489
10959836
|
BRCA1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BLM
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
XRCC5
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
CDK2
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9781043
16322221
16123081
11292842
10928988
|
MLH1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9781043
16322221
16123081
11292842
10928988
|
H2AFX
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATM
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
ATM
|
ABRAXAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
ATM
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
100.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12086603
12202749
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
WRN
|
ATM
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12202749
12607003
15140942
15211575
15385537
15459660
15498778
15964794
16163361
16449207
17055429
17116323
17303408
17965729
18087292
18171986
18398454
18524993
18558713
18584027
18809224
19202191
19362533
19490890
19654615
19772495
19793801
19892829
20027199
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
9721205
|
H2AFX
|
ATM
|
â—¼ SHARES_COMPLEX
|
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
MDC1
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATM
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
100.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12086603
12202749
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
H2AFX
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
RPA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
PARP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
MDC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATM
|
TERF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11331603
11877377
12607003
15140942
15459660
15964794
16163361
17303408
22266654
22634377
23847781
|
ATM
|
FANCD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
MSH2
|
ATM
|
â—¼ UP_REGULATES
|
✅
|
+
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
MLH1
|
ATM
|
â—¼ UP_REGULATES
|
✅
|
+
|
16.0
|
1.0
|
ACSN
|
12556884
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
17581638
18157157
18406444
18543256
19151707
19847258
20478261
|
MSH6
|
ATM
|
â—¼ UP_REGULATES
|
✅
|
+
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
H2AFX
|
ATM
|
â—¼ REGULATES
|
✅
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
MDC1
|
â—¼ REGULATES
|
✅
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATM
|
RAD50
|
â—¼ REGULATES
|
✅
|
|
100.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12086603
12202749
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
AURKB
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22099307
27493659
|
ATR
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15510216
10608806
17478428
17124492
|
ATM
|
RPA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
29875999
15964794
11877377
17303408
9725899
16163361
14872059
23847781
9139719
10713094
9295339
20860841
16731533
12607003
22977173
7171818
15459660
|
ATM
|
TERF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16223874
17525332
15314656
|
ATM
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
452.0
|
1.0
|
Omnipath
|
25301947
21720806
23549171
10713094
16501611
15077171
24886358
17570479
19375142
22028490
16916644
14712210
19303885
9407038
11927276
26700820
28356518
15226429
10723129
19788889
12064478
19705844
26673821
22179422
20931131
19062161
27030982
22891162
17157788
19056039
15758953
12049739
15361830
26620371
25865756
22615843
10196661
10656682
11313957
25088203
15140942
12519769
16319535
24469230
12776195
17234789
27511909
29238697
24608431
12927814
16783362
11875057
16436515
22778557
15181149
12702572
10500142
15178764
28842590
28145533
11591448
17855337
22726545
20206688
26824362
21317290
26104798
24704793
9765199
11314044
16906133
17174997
21593792
17967874
10771484
15585169
19625493
15178448
17596534
16288207
15048074
18353733
24057508
19535302
29344296
23708100
29872395
23705030
25043304
33761896
18431490
21404020
15024084
22559321
12151394
24078877
12080066
33982778
16893723
10958792
18289945
27183917
26337656
29170437
18765533
10744722
21748595
18056442
24820418
15489892
16390936
24086335
28140789
23091651
34523970
32001619
23418564
15279808
21317932
21188172
27559048
16818505
17616578
11551930
19010925
11709713
24711418
28654064
18339864
11173129
17486112
10570149
29774100
18381438
21994612
29558908
15258567
9372954
25860929
16858402
33692124
15775976
34107253
19923893
24958101
10436023
14752509
19962312
19071090
26438152
26093282
20123963
22444248
9843217
17525332
15456784
23533526
11780126
20353948
29290977
11096068
28102346
18855897
20372057
24395704
23890999
15725625
15806145
34103468
18345031
16997395
16293623
28477117
19828454
27630139
12071847
22002314
21315088
27177180
12645530
12890678
26113041
15794754
18560558
22099307
9885574
28903382
15665826
24877058
18332866
10611322
24380814
14871840
19934315
22975381
16489034
18406507
21440540
33687951
10608806
23892398
20730097
16914171
15782130
15177184
22055193
18490454
25867001
24349352
18045533
20663147
17535811
20506250
23982736
22375140
15700044
15279774
19266268
24358288
18697815
14729946
20637859
12242661
12771937
17371838
31940492
19409520
10528155
24037342
17257427
11121242
15310764
23148227
28915641
26928575
21423215
11865061
16949371
27810895
18449195
20711232
27389279
22213803
16713569
10446957
22797063
16478990
29048667
15489221
17241873
21187893
21441950
23907539
20005840
9733514
26244501
21614094
12082529
10467728
10714958
32061892
16636671
29147215
10673501
12091386
25202122
21465263
19544417
25823026
24078903
24038750
22198295
21480565
15177039
28182994
28208785
18674635
20183804
18818083
9925639
17712528
15254178
11483158
27940348
26675349
26261212
19717643
12606585
24559687
14871926
23150668
21329876
28153791
12518062
12767922
23824039
11711532
19251701
28118604
15078887
12393500
17456577
20976220
23380594
12519780
20810927
15533933
22420423
17108107
20145032
18032786
18785202
22037398
23184057
31968249
16729035
12588868
21614932
11546806
18614045
14757188
15029243
14968111
22649771
25512053
34496248
18604166
17609585
17976513
16223874
25433195
18985806
9363941
15159397
34282274
29301278
24505404
26056062
23577291
18272544
18715874
19536869
29334356
10801407
15155458
25201202
24376853
19907922
23525106
14643431
28340339
28051100
19085961
15212693
22201816
20026654
16322229
20080565
9733515
15632067
18672098
22577550
25691451
12637545
12548019
11672523
26984736
12324477
16552184
22084686
10864201
14744854
21532626
17118344
19482562
9561848
12511424
17668048
23358251
18511169
21460853
22022355
12939400
21415014
17292432
25651062
23168260
12111733
16648554
30361254
23678107
|
ATM
|
FANCD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
16280053
17303408
15057286
12427531
15607958
25891850
16163361
21466974
20068231
14499622
17570479
12086603
19774700
23847781
14599770
15964794
22057367
28825622
12607003
17525332
15459660
16943440
15979372
11877377
27094386
15279770
28552166
12612651
19101576
|
ATM
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
80.0
|
1.0
|
Omnipath
|
12433983
12861053
17485521
23146902
10839545
19413330
15302935
27602502
17429352
19523210
24360018
20068231
17507690
17570479
10608806
12598907
18669648
25088203
18003706
11252893
17431132
23097684
10766245
12814430
10802669
21664921
26512707
10839544
11927276
21130714
17525332
12447395
14707289
15733840
15279770
25119968
18644472
28822740
|
ATM
|
TP53BP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
11042216
17940005
26247731
18996087
19876065
16945145
12447390
22621922
18644834
19650866
24320053
18077418
17570479
17690115
17525332
12697768
|
ATM
|
TOPBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11756551
18077418
19279141
17525332
17446169
|
ATM
|
RPA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17525332
11359916
|
ATM
|
BLM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16199871
11146546
25766002
17984114
14643436
20719863
17363339
14729972
18054789
12034743
30496191
16880735
11375976
|
ATM
|
MRE11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19709933
26240375
17570479
31353207
10608806
|
ATM
|
SMC1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
17303408
14657349
19690332
29988990
26673124
15302935
16163361
20068231
18452278
18077418
17570479
18669648
23847781
15964794
16906133
12607003
9789013
17525332
15459660
11877376
11877377
|
ATM
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
23468639
23675572
17570479
24837676
10910365
16249056
11689934
10608806
17525332
22743550
|
ATM
|
TERF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
17717821
15314656
17570479
23732473
26586433
11375976
22266654
|
ATM
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
197.0
|
1.0
|
Omnipath
|
27410735
28544233
16426903
28797244
9488723
23847653
30197789
21930799
18158901
21693595
18848500
22819196
15603757
16760673
17570479
24688021
24793032
27458206
16531125
22028490
30154456
19230794
23202908
25852739
19059218
26073471
22247744
28259974
29584802
25691887
19049966
20368801
26700820
29386061
28124509
20613862
27550454
20847938
27388041
27752097
23269287
24480460
22237206
20461094
20971043
26941327
18285803
21690091
15279774
23891287
25847270
24490130
25349305
26906421
20637859
26314960
15286739
27780918
20454618
30013081
28671946
25218945
23742011
26391293
23972723
23382699
26416514
27442013
20703100
24726884
26512707
27332952
29641431
25287622
26295265
14643438
29163809
25264544
19895790
26504743
26113859
27431324
28790385
18413980
21283714
21787120
20205745
19781914
25093845
27135971
23227178
22224778
20923785
20860841
24244154
23386996
30065307
16858402
11879731
28009280
23343929
20192759
22761798
26855420
24378750
20068231
20580718
14504478
24893124
29048667
25661368
26860083
26019182
20488183
28764946
22205726
23977391
18471973
19591958
28239143
20542002
17525332
20495376
18755145
23050241
17782711
11571274
19473884
28431265
25742493
18248856
17690115
20684759
26317467
21727091
24651472
25827888
27164092
28587922
20976184
30723510
20471486
23772364
29794999
11893489
19014481
20165693
26671524
16997395
20936109
26114388
23845989
15138496
22761813
23355489
27455285
28943310
21348461
19647519
23678292
23166506
28099474
29434792
25249630
25269479
27310012
15177039
22559321
26045162
20865059
22972376
21148072
26760771
21188122
22962268
22768044
26711340
20460517
27845910
28855246
|
ATM
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
26927092
17303408
15159397
24746700
12024016
10866324
30197789
12919958
11114888
26745677
26383678
34301763
12427729
11313470
16163361
28035057
20068231
25939603
26320175
17570479
19683496
22743550
10608806
23802008
23847781
21203981
15964794
12183412
12607003
17525332
19996295
15459660
11278964
19651622
21706030
11877377
20952512
10373534
19622773
10550055
27170701
15212693
23704879
|
ATM
|
ABRAXAS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17525332
17525340
26778126
|
ATM
|
RAD50
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17570479
17081983
15302935
|
ATM
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
28193847
21705321
22234877
12607003
12607005
22234878
17525332
18006705
|
PCNA
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
47.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
1974050
19793801
19847258
20051983
22021614
23414611
|
RPA2
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
61.0
|
1.0
|
ACSN
|
10884395
11756412
11877377
12086603
12466554
12766152
12875843
14614141
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15242590
15375219
15377654
15459660
15485915
15703371
15743907
15798197
16530042
16697054
16713580
16805667
16818604
16880517
16885023
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
17855402
18157158
18451105
18469862
18543256
18677104
18931676
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
19686080
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
11850621
11877377
12086603
12607003
14988723
15136767
15175241
15459660
15798197
16713580
16805667
17102137
17116885
17296725
17384638
17582221
18087292
18469862
18584027
18677104
18809224
18931676
18995830
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
22751496
23444773
24050180
|
ATR
|
FANCD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
58.0
|
1.0
|
ACSN
|
11438669
11850621
11877377
12086603
12607003
14988723
15136767
15175241
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16805667
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18087292
18469862
18511906
18543256
18584027
18677104
18716619
18756267
18809224
18931676
18995830
19004803
19282663
19342888
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
20723763
21376743
22743550
22751496
23444773
24050180
9488723
9858600
|
ATR
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
TOPBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11877377
12766152
15459660
15485915
15798197
16530042
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17582221
18677104
19282663
19622404
19793801
|
PCNA
|
ATR
|
â—¼ SHARES_COMPLEX
|
|
|
47.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
ATRIP
|
â—¼ SHARES_COMPLEX
|
|
|
61.0
|
1.0
|
ACSN
|
10884395
11756412
11877377
12086603
12466554
12766152
12875843
14614141
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15242590
15375219
15377654
15459660
15485915
15703371
15743907
15798197
16530042
16697054
16713580
16805667
16818604
16880517
16885023
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
17855402
18157158
18451105
18469862
18543256
18677104
18931676
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
19686080
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
FANCD2
|
â—¼ SHARES_COMPLEX
|
|
|
58.0
|
1.0
|
ACSN
|
11438669
11850621
11877377
12086603
12607003
14988723
15136767
15175241
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16805667
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18087292
18469862
18511906
18543256
18584027
18677104
18716619
18756267
18809224
18931676
18995830
19004803
19282663
19342888
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
20723763
21376743
22743550
22751496
23444773
24050180
9488723
9858600
|
ATR
|
TOPBP1
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11877377
12766152
15459660
15485915
15798197
16530042
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17582221
18677104
19282663
19622404
19793801
|
ATR
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
11850621
11877377
12086603
12607003
14988723
15136767
15175241
15459660
15798197
16713580
16805667
17102137
17116885
17296725
17384638
17582221
18087292
18469862
18584027
18677104
18809224
18931676
18995830
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
22751496
23444773
24050180
|
MSH2
|
ATR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
MSH6
|
ATR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
MLH1
|
ATR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
12556884
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
17581638
18157157
18406444
18543256
19151707
19847258
20478261
|
ATR
|
FANCD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
58.0
|
1.0
|
ACSN
|
11438669
11850621
11877377
12086603
12607003
14988723
15136767
15175241
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16805667
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18087292
18469862
18511906
18543256
18584027
18677104
18716619
18756267
18809224
18931676
18995830
19004803
19282663
19342888
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
20723763
21376743
22743550
22751496
23444773
24050180
9488723
9858600
|
ATR
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
42.0
|
1.0
|
ACSN
|
11438669
11877377
14988723
15136767
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18511906
18543256
18677104
18716619
18756267
18931676
18995830
19004803
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
9488723
9858600
|
ATR
|
PARP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
42.0
|
1.0
|
ACSN
|
11438669
11877377
14988723
15136767
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18511906
18543256
18677104
18716619
18756267
18931676
18995830
19004803
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
9488723
9858600
|
ATR
|
H2AFX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
42.0
|
1.0
|
ACSN
|
11438669
11877377
14988723
15136767
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18511906
18543256
18677104
18716619
18756267
18931676
18995830
19004803
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
9488723
9858600
|
RPA2
|
ATR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RPA1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RPA3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
BLM
|
ATR
|
â—¼ UP_REGULATES
|
✅
|
+
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
RPA2
|
ATR
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RPA3
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RPA1
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
MSH2
|
ATR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19847258
16612326
14657349
16713580
20478261
15703371
18543256
12947387
19473888
19595721
19596235
18157157
16697054
19596236
18406444
21285353
|
TOPBP1
|
ATR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16530042
18769153
16285702
18066086
|
ATR
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
26927092
17478428
24746700
15159397
17531442
10866324
18677104
19622404
15798197
19793801
20860841
16713569
11114888
23422745
20936109
16322207
19282663
20068231
17116885
17582221
25879655
10608806
17384638
23346553
12773400
12183412
17525332
15459660
11278964
17296725
11877377
17102137
10550055
16522651
|
ATR
|
SMC1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
18442975
14657349
17526493
18677104
19622404
15798197
19793801
19282663
17116885
17582221
18077418
17384638
21908846
17525332
15459660
11877376
18832153
17296725
11877377
16087684
17102137
|
ATR
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
18677104
19622404
15798197
19793801
15485915
24842372
20051983
19282663
17116885
17582221
17384638
23273981
18511906
18716619
19490890
15459660
30135856
19357644
17296725
11877377
17102137
25956864
|
ATR
|
FANCD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
27713304
16943440
27094386
22057367
15616588
18077418
18082599
14988723
19101576
|
ATR
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
68.0
|
1.0
|
Omnipath
|
20461094
20976184
20471486
22224778
17303408
28797244
18677104
19622404
15798197
19793801
9488723
20860841
12919958
18158901
20165693
20936109
22002605
26114388
29114052
21283714
22819196
19282663
24893124
17116885
22531632
17582221
30013081
25438756
26019182
17384638
19647519
20205745
23166506
25852739
18471973
27442013
22247744
29584802
20542002
19875294
25249630
20368801
15459660
27332952
27715493
19772495
25247188
17296725
11877377
14643438
24813610
20613862
17102137
20847938
21148072
23443128
27431324
29163782
23754961
17690115
15975956
18663141
21787120
22545090
27077811
19781914
27164092
|
ATR
|
ATRIP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20616048
15451423
19889979
23144622
17686975
18344416
|
ATR
|
RPA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
28666352
23684611
19440044
20860841
18289945
24819595
25520194
19843584
10608806
26057167
17035231
24906880
27908669
22977173
25249630
25070753
26271993
23319600
26212458
29875999
24965470
26474068
|
ATR
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17715134
15758953
17526493
18077418
|
ATR
|
XRCC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23438602
26354865
|
ATR
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
106.0
|
1.0
|
Omnipath
|
17145710
22778941
24395704
28468838
12401524
15159397
24877058
15254178
9733515
11483158
15806145
19056039
11875057
15865930
11551930
11883897
19923893
12548019
18697815
29170437
16293623
19010925
11709713
10446957
9363941
21748595
17272272
22797063
12242661
10196661
22084686
10747897
10608806
10673501
12091386
17118344
23892398
9765199
15489221
24037342
15140942
10435622
17241873
10597277
10801407
11711532
17174997
21593792
25201202
9843217
10606744
15024084
15226429
15922368
21415014
21480565
15585169
24947324
9925639
23380594
9733514
11865061
19625493
16390936
10951572
10570149
23311997
12111733
26144601
|
RPA1
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA2
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA3
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
PCNA
|
ATRIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
47.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
1974050
19793801
19847258
20051983
22021614
23414611
|
ATRIP
|
TOPBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11877377
12766152
15459660
15485915
15798197
16530042
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17582221
18677104
19282663
19622404
19793801
|
PCNA
|
ATRIP
|
â—¼ SHARES_COMPLEX
|
|
|
47.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
1974050
19793801
19847258
20051983
22021614
23414611
|
ATRIP
|
TOPBP1
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11877377
12766152
15459660
15485915
15798197
16530042
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17582221
18677104
19282663
19622404
19793801
|
MSH6
|
ATRIP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
MSH2
|
ATRIP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
MLH1
|
ATRIP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
12556884
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
17581638
18157157
18406444
18543256
19151707
19847258
20478261
|
RPA1
|
ATRIP
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA2
|
ATRIP
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA3
|
ATRIP
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA3
|
ATRIP
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA2
|
ATRIP
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA1
|
ATRIP
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA1
|
ATRIP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15743907
12791985
16407120
17339343
|
CDK2
|
ATRIP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20195506
17638878
|
ATRIP
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24073851
17616665
|
BABAM1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19261748
19261749
|
NFKB1
|
BCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
11313951
11704864
21725609
23178297
23572150
|
NFKB1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
16254192
11567031
17673602
18031796
12835724
15120608
20332461
14978135
20446017
18566231
19259124
14739605
21503108
20103608
17098279
18158998
12032828
19233129
16022909
18761399
18987666
15934930
21224428
16453001
|
RELA
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17673602
18031796
12835724
15120608
20332461
14978135
20446017
18566231
19259124
14739605
21503108
20103608
17098279
18158998
19233129
16022909
18761399
18191642
21224428
16453001
|
ESR1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
19148464
19160418
9306964
11261829
21841772
10542244
20664923
18414489
|
TP53
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
17693666
8183578
10037739
16738310
18397889
19521340
18487508
21666495
16294215
21656028
22869582
19714248
10744634
8174112
17592775
11782367
19137013
20428827
18682598
11713302
11313951
20501806
9649502
24814047
15767042
24098340
11193470
10329733
21859835
22266868
10953306
19555669
23638218
14684736
19411072
20530667
24155778
8205530
20840522
9000137
15326476
|
TP53
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12667443
19555669
8205530
19007744
11313951
|
CDK1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
24097825
24677263
23638364
19917720
27231850
11774038
11326318
10766756
|
BCL3
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11387332
24459141
14573596
7896265
|
BCL3
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17962807
10453354
16108830
11931770
16513645
8428580
8330739
17561400
10362352
9218802
21912613
17183360
14678988
18668140
10469655
|
MRE11
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
NBN
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BRCA1
|
BLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BLM
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BLM
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BLM
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
12535671
12972610
15496928
15549137
15655342
16537486
16595695
16697054
18001825
18171670
18212739
18550849
18931676
19217833
19270065
19282663
19490890
19622404
19686080
19772495
19847258
19945966
20021983
20064462
20826342
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
BLM
|
TOP3A
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
12535671
12972610
15496928
15549137
15655342
16537486
16595695
16697054
18001825
18171670
18212739
18550849
18931676
19217833
19270065
19282663
19490890
19622404
19686080
19772495
19847258
19945966
20021983
20064462
20826342
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
BLM
|
WRN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
16697054
18931676
19622404
19686080
19772495
19847258
22266823
22657828
22973052
23253856
24089143
24095737
|
BLM
|
PCNA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
16697054
18931676
19622404
19686080
19772495
19847258
22266823
22657828
22973052
23253856
24089143
24095737
|
BLM
|
TERF2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
16697054
18931676
19622404
19686080
19772495
19847258
22266823
22657828
23253856
24089143
24095737
|
BLM
|
RAD50
|
â—¼ UP_REGULATES
|
✅
|
+
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
BLM
|
FANCD2
|
â—¼ UP_REGULATES
|
✅
|
+
|
35.0
|
1.0
|
ACSN
|
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
16337602
16697054
17035102
18157158
18448394
18469862
18472307
18550849
18931676
19217833
19225445
19258535
19282663
19622404
19686080
19772495
19847258
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
|
TERF2
|
BLM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
15229185
19329795
12181313
|
TERF1
|
BLM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17145710
15229185
|
BLM
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12080066
11399766
22653443
24239288
15806145
11781842
16713569
15364958
|
NBN
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
PCNA
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
BRCA1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
BRCA1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
BRCA1
|
BRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BRCA1
|
FANCD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
RAD52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
BRCA1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
PCNA
|
BRCA1
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
BRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCA1
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
BRCA2
|
â—¼ SHARES_COMPLEX
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
H2AFX
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
RAD52
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
FANCD2
|
â—¼ SHARES_COMPLEX
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
BRCA1
|
XRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
TP53BP1
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
BRCA1
|
AURKA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
MDC1
|
BRCA1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
17303408
17660363
18001824
18006705
18087291
18583988
18590585
18678890
7575488
9407949
|
E2F4
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
20133863
21701264
17531812
17001309
20818429
17106239
23108140
|
TP53
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
9582019
11295099
18625847
11003642
12802282
16357511
14710355
9619832
19882681
10884389
11384963
11782367
12024039
15735697
12170778
21245169
17993233
12549011
11431698
16229810
18208621
10597265
21742769
|
BAP1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16713569
9528852
|
E2F4
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9244350
18319725
16713569
12909625
|
UIMC1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17525341
17525342
17525340
17621610
|
BARD1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
99.0
|
1.0
|
Omnipath
|
16403807
16391231
28262780
15159397
25652403
26350354
26490435
14647430
11927591
25184681
16713569
11526114
35203293
9738006
12732733
24289923
11573085
18936166
23086937
24085845
12890688
15855157
24695549
19369211
9798686
11257228
11498787
12700228
11925436
10477523
19176389
23680151
25634209
23416467
34726323
29355525
18369654
14636569
11504724
12951069
19117993
20060929
17873885
14638690
18493658
11278247
15184379
22110403
11301010
11773071
12431996
10635334
20029420
9788437
17664283
21901007
25252691
12485996
10026184
12438698
17525341
16489000
8944023
15265711
12419249
20681793
9342365
27239795
20215511
25823446
19916563
|
ABRAXAS1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17643122
19261749
22357538
17525340
19261746
21282113
19261748
25184681
17643121
19305427
23416467
|
CDK2
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8764100
10373534
10550055
19683496
16713569
26719576
15212693
|
AURKA
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
22864622
22340593
18026198
24775809
14990569
|
UBE2D3
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
11927591
21531767
16713569
21756275
12732733
22863316
17349954
21113135
25355358
21532592
18369654
16818604
20351172
15905410
16628214
19712108
21965653
15886201
15367667
23246971
12438698
17283126
|
MDC1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
18087291
17525332
12607005
|
CDK1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9244350
21706030
10550055
17570479
19683496
16713569
26745677
32193285
26719576
|
BRIP1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
22032289
21240188
34591612
18285836
16713569
14576432
17596542
17525342
17525340
15242590
25184681
19369211
18369654
28911102
17581638
15125843
11301010
15133502
19452558
27399284
18717574
17525341
22792074
14576433
20173781
11877378
20681793
14578343
|
RAD50
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10783165
16260778
16391231
10426999
11504724
25084169
25184681
16713569
|
BRCA1
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
21908405
18285836
16713569
15485915
25310973
9738006
17525342
17525340
16843262
24085845
25184681
26387952
18369654
9811458
16818604
20351172
23416467
19442256
10196224
10910365
19452558
11739404
25252691
10764811
25659039
17965729
11689934
|
BRCA1
|
FANCD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12887909
12485996
11239454
25652403
14499622
16713569
|
BRCA1
|
PALB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
26649820
19268590
28089683
28319063
19369211
|
BRCA1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11244506
12400015
15674350
10334989
16713569
11493692
|
BRCA1
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18001824
18001825
17145710
12419185
|
PCNA
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
FANCD2
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
RAD52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA2
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA2
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
48.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15496928
15549137
15590677
15650050
15655342
16337602
16697054
17349954
18001825
18171670
18212739
18660752
18931676
19217833
19270065
19473888
19490890
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20021983
20029420
20064462
20081207
20376879
20723763
20813759
21060331
21337561
22266823
22505525
22751496
22771115
23444773
|
BRCA2
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
FANCD2
|
BRCA2
|
â—¼ SHARES_COMPLEX
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
BRCA2
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA2
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
H2AFX
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA2
|
RAD52
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA2
|
XRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
48.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15496928
15549137
15590677
15650050
15655342
16337602
16697054
17349954
18001825
18171670
18212739
18660752
18931676
19217833
19270065
19473888
19490890
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20021983
20029420
20064462
20081207
20376879
20723763
20813759
21060331
21337561
22266823
22505525
22751496
22771115
23444773
|
TP53
|
BRCA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9619832
11295099
18765668
12591928
|
PALB2
|
BRCA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
17420451
16793542
26990772
19268590
22293751
17488615
19369211
23585894
24485656
20332121
24141787
26649820
19553677
17200672
26833090
23038782
17200668
15115758
19609323
30410870
19584259
22193777
|
SEM1
|
BRCA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17145710
26833090
26145171
22293751
24013206
10373512
16205630
16239144
17563742
12228710
|
FANCD2
|
BRCA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
17145710
19861535
15115758
18212739
15199141
10749118
|
BRCA2
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
87.0
|
1.0
|
Omnipath
|
17145710
21601571
15937124
17541404
11313963
16914443
26145171
21670257
18264088
19303847
25585578
12815053
16793542
21789034
25282148
17515904
9126738
20729859
15703751
21076401
15065660
22293751
19875419
12606939
22116401
12619154
23935068
15800615
33476590
15800651
15671039
11477095
16513631
9811893
10551859
20729832
9523196
14636569
17515903
12442171
9405383
26833090
21399666
19628690
9560268
10373512
14580352
|
BARD1
|
BRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BARD1
|
BRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
BRCC3
|
TP53BP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
TOP3A
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
WRN
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
NBN
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RBBP8
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RAD50
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
KAT5
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
MRE11
|
BRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
TOPBP1
|
BRIP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20159562
25374583
|
RPA1
|
BRIP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17596542
19419957
|
CBX1
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
15136563
11882902
16622419
20871592
11242053
19111658
15960974
16415788
26527279
|
CBX3
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15136563
20871592
20011120
24576085
19111658
16415788
26527279
|
E2F4
|
CBX5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17531812
11799066
|
CBX5
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16687578
16622419
20871592
20011120
25281560
26527279
19111658
16415788
19498464
|
CDK1
|
RPA3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
14551205
15279786
17102137
17116885
17296725
17303408
17582221
17660363
18414028
18590585
19793801
7575488
|
CDK1
|
GOLGA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
Reactome
|
15678101
7737117
11238451
11306556
18167358
1902553
9150144
10679020
9753325
11285137
|
CDK1
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
14551205
15279786
17102137
17116885
17296725
17303408
17582221
17660363
18414028
18590585
19793801
7575488
|
CDK1
|
TP53BP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
14551205
15279786
17243194
17303408
17660363
18414028
18590585
7575488
|
CDK1
|
TERF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
14551205
15279786
17303408
17660363
18414028
18590585
18625707
22624377
7575488
|
CDK1
|
RPA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
14551205
15279786
17102137
17116885
17296725
17303408
17582221
17660363
18414028
18590585
19793801
7575488
|
TP53
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
10825186
11593387
12874009
19472317
10514438
11313928
16807237
8270002
17942917
9275177
20395210
11032828
19861536
12889596
19067706
|
E2F4
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15510213
17671431
11799067
11032828
17121828
17531812
|
E2F4
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15510213
16135806
|
CDK1
|
TP53BP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
7575488
18590585
17243194
17303408
21524151
17570479
25607646
29603287
20126263
17660363
30685087
15279786
|
CDK1
|
KAT5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
21658600
12468530
16103124
17570479
26829474
18669648
|
CDK1
|
KAT7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18250300
19690332
19413330
23955388
16964243
18669648
|
CDK1
|
RPA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
9139719
17303408
9295339
19793801
15279786
7575488
20068231
17116885
19671522
17582221
26237679
18590585
1318195
22977173
17660363
20932174
17296725
17102137
21664290
|
CDK1
|
NPM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
49.0
|
1.0
|
Omnipath
|
17081983
12058066
27253419
22285574
25908633
20333249
16912078
27553022
19933706
16083285
20068231
27619510
17570479
18669648
7213797
81161106
26536659
11278991
17287340
17924679
15190079
14670079
|
CDK1
|
UBA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
19651622
20068231
7724583
19413330
7673335
18669648
9099746
|
CDK1
|
FBXO5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17875940
17660363
15279786
15917306
|
CDK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
24173284
12767922
1584757
20661218
26029996
2141171
9467949
17570479
20808790
7862459
11327730
11078726
27726420
8357826
16713569
2156209
|
CDK1
|
GOLGA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
19007248
19691289
18691976
9753325
20068231
10769027
16964243
18669648
|
CCNE1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
CDK2
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9781043
16322221
16123081
11292842
10928988
|
CDK2
|
RPA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
RPA3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
E2F4
|
CDK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17531812
22447046
|
CDK2
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23623683
33097710
27308383
24236237
19202191
24982848
25956864
22743550
|
CDK2
|
NPM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
67.0
|
1.0
|
Omnipath
|
32076484
26123729
17081983
27998958
16565220
19007248
19367720
23840880
12058066
19690332
22285574
25922180
21272329
19413330
20333249
24282781
32092641
27553022
19933848
19933706
16083285
18318008
20068231
24998852
23627734
26993766
18165222
17535915
18669648
24290756
17942908
81161106
18691976
11278991
19561638
17287340
16376875
18243139
19651622
17924679
18220336
24282525
19369195
15190079
25531824
18212344
|
CDK2
|
SKP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
7553852
20160477
23602568
25271736
18239684
28446188
23226679
10386600
19270695
26496610
16189514
25852190
26186194
25788262
9858587
22770219
15355997
10559858
23807222
22311674
16979657
9636170
19686743
19270694
18604603
23455922
|
CDK2
|
FOXK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20810654
|
CDK2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10428798
22431515
23390529
17570479
23770852
|
CDK2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
24173284
9315650
19413330
19664995
16083285
1088347
16552184
10884347
17570479
10747897
25241761
7624134
11687964
17287340
92065884
12064478
19556892
14640983
10348343
14702041
|
CDK2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
50.0
|
1.0
|
Omnipath
|
17145710
16223725
21092281
15004009
10962581
9840943
8643455
24358021
8861947
21372285
17570479
11237742
10330164
22558078
10652300
19561641
10477583
18691976
23853094
12144826
10500095
1388288
10827081
17970072
28137908
19470470
8756624
10809788
14536078
15364936
|
CDK9
|
POLR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
22053051
20222012
25023704
14662762
10364292
20106982
18066052
30135578
24385927
18644870
18329373
14517250
20932174
12052871
20226668
19575011
8416977
11575923
16735508
|
CDK9
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
24173284
9372954
11483158
9315650
19413330
19664995
23603988
24202322
11709713
16083285
1088347
16552184
10884347
24286312
10747897
17942552
16741955
17287340
92065884
12064478
10348343
14702041
|
MSH2
|
EME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
EME1
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
EME1
|
MSH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MSH2
|
EME1
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
EME1
|
MSH3
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
EME1
|
MUS81
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
PCNA
|
FANCD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
FANCD2
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
FANCD2
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
FANCD2
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
FANCD2
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
63.0
|
1.0
|
ACSN
|
10882712
11850621
11877377
12086603
12556884
12607003
14988723
15136767
15175241
15211575
15459660
15498778
15798197
15964794
16163361
16332722
16337602
16531125
16581787
16713580
16805667
16858402
17036055
17102137
17116885
17296725
17303408
17384638
17582221
17713585
17965729
18087292
18171670
18469862
18584027
18677104
18809224
18931676
18995830
19151707
19282663
19342888
19362533
19622404
19654615
19686080
19772495
19793801
19793861
19793862
19805513
19841479
19892829
20051983
20064462
20723763
21376743
22743550
22751496
23444773
24050180
24089143
24095737
|
FANCD2
|
POLN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
16337601
16337602
16697054
17965729
18087292
18448394
18472307
18584027
18809224
18931676
19622404
19686080
19772495
19793861
19793862
19841479
19847258
19995904
20064462
20723763
22101340
22751496
23444773
|
FANCD2
|
RAD52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
FANCD2
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
FANCD2
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
PCNA
|
FANCD2
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
FANCD2
|
RAD52
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
FANCD2
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
63.0
|
1.0
|
ACSN
|
10882712
11850621
11877377
12086603
12556884
12607003
14988723
15136767
15175241
15211575
15459660
15498778
15798197
15964794
16163361
16332722
16337602
16531125
16581787
16713580
16805667
16858402
17036055
17102137
17116885
17296725
17303408
17384638
17582221
17713585
17965729
18087292
18171670
18469862
18584027
18677104
18809224
18931676
18995830
19151707
19282663
19342888
19362533
19622404
19654615
19686080
19772495
19793801
19793861
19793862
19805513
19841479
19892829
20051983
20064462
20723763
21376743
22743550
22751496
23444773
24050180
24089143
24095737
|
FANCD2
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
FANCD2
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
FANCD2
|
XRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
FANCD2
|
H2AFX
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
FANCD2
|
POLN
|
â—¼ SHARES_COMPLEX
|
|
|
23.0
|
1.0
|
ACSN
|
16337601
16337602
16697054
17965729
18087292
18448394
18472307
18584027
18809224
18931676
19622404
19686080
19772495
19793861
19793862
19841479
19847258
19995904
20064462
20723763
22101340
22751496
23444773
|
FANCD2
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
FANCD2
|
RAD50
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
63.0
|
1.0
|
ACSN
|
10882712
11850621
11877377
12086603
12556884
12607003
14988723
15136767
15175241
15211575
15459660
15498778
15798197
15964794
16163361
16332722
16337602
16531125
16581787
16713580
16805667
16858402
17036055
17102137
17116885
17296725
17303408
17384638
17582221
17713585
17965729
18087292
18171670
18469862
18584027
18677104
18809224
18931676
18995830
19151707
19282663
19342888
19362533
19622404
19654615
19686080
19772495
19793801
19793861
19793862
19805513
19841479
19892829
20051983
20064462
20723763
21376743
22743550
22751496
23444773
24050180
24089143
24095737
|
E2F4
|
FANCD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17531812
11799066
|
E2F4
|
FBXO5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17531812
18439978
|
HERC2
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
HERC2
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
HERC2
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
HERC2
|
ABRAXAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
HERC2
|
RNF8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20023648
22508508
25305019
22814251
|
XRCC6
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
ABRAXAS1
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
TOP3A
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
WRN
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
XRCC5
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
KAT5
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
KAT5
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
KAT5
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17188038
15310756
18280244
16601686
|
XRCC5
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
RAD50
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
59.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
H2AFX
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
81.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16049003
16163361
16332722
16377563
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17349954
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678709
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19490890
19622404
19686080
19772495
19793801
19793861
19793862
19841479
20021983
20051983
20064462
20101220
20118229
20723763
21376743
22743550
22771115
23847781
24050180
7575488
9407949
9488723
|
XRCC6
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
MDC1
|
RNF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
15496928
15549137
15655342
17303408
17660363
18001824
18001825
18006705
18087291
18171670
18212739
18583988
18590585
18678709
18678890
18809224
19217833
19270065
19490890
19772495
20021983
20064462
7575488
9407949
|
MDC1
|
ABRAXAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
H2AFX
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
81.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16049003
16163361
16332722
16377563
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17349954
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678709
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19490890
19622404
19686080
19772495
19793801
19793861
19793862
19841479
20021983
20051983
20064462
20101220
20118229
20723763
21376743
22743550
22771115
23847781
24050180
7575488
9407949
9488723
|
MDC1
|
RNF8
|
â—¼ PROTEIN_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
15496928
15549137
15655342
17303408
17660363
18001824
18001825
18006705
18087291
18171670
18212739
18583988
18590585
18678709
18678890
18809224
19217833
19270065
19490890
19772495
20021983
20064462
7575488
9407949
|
RAD50
|
MDC1
|
â—¼ SHARES_COMPLEX
|
|
|
59.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
H2AFX
|
MDC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
81.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16049003
16163361
16332722
16377563
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17349954
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678709
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19490890
19622404
19686080
19772495
19793801
19793861
19793862
19841479
20021983
20051983
20064462
20101220
20118229
20723763
21376743
22743550
22771115
23847781
24050180
7575488
9407949
9488723
|
MDC1
|
RNF8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
15496928
15549137
15655342
17303408
17660363
18001824
18001825
18006705
18087291
18171670
18212739
18583988
18590585
18678709
18678890
18809224
19217833
19270065
19490890
19772495
20021983
20064462
7575488
9407949
|
MDC1
|
TP53BP1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
17303408
17660363
18001824
18006705
18087291
18583988
18590585
18678890
7575488
9407949
|
H2AX
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
21676867
14519663
18001824
21293379
16427009
16377563
18583988
21622030
18001825
12607005
19234442
20159462
15201865
|
MDC1
|
TP53BP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16009723
17145710
18087291
17925396
12607005
|
MDC1
|
RNF8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
24240613
18001824
25512560
18001825
18678647
18082599
18006705
|
MDC1
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
17145710
15201865
20460517
23115235
14519663
18001824
18678890
19804756
18583988
19230643
12607003
12607005
20224574
|
TP53
|
MKI67
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21611785
11713584
10365096
15217513
16258956
14675138
|
PCNA
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
20154325
22118461
11274057
23840062
|
PCNA
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
20154325
22118461
11274057
23840062
|
MSH2
|
MSH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MSH2
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MSH2
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
11307145
11948476
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
16879101
17129768
17303408
17395641
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
23507534
|
MSH2
|
MSH6
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
11307145
11948476
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
16879101
17129768
17303408
17395641
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
23507534
|
MSH2
|
MSH3
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MSH2
|
MUS81
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MUS81
|
MSH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MUS81
|
MSH3
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
PCNA
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
20713735
20154325
22118461
11274057
11441019
11005803
18326858
17984070
11809883
16188885
16143102
|
RAD54L
|
MUS81
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19017809
|
NBN
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
NBN
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
NBN
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
NBN
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
NBN
|
ABRAXAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
NBN
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
MRE11
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
22464731
26455393
12861053
17500065
15734743
12419185
19270065
22078559
19244116
21884979
12679336
11238951
12607003
9705271
17713585
10783165
12447395
10426999
18458108
15758953
|
NPM1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
23443559
15144954
16740634
15310764
16376884
12080348
|
RAD51B
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
XRCC2
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
RAD51D
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
PALB2
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19423707
20871616
24141787
|
PARG
|
PARP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
196269035
22469522
22713970
23110147
24684389
|
PARG
|
PARP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
22469522
22713970
196269035
17276427
|
PCNA
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
12607003
14726013
15175241
15459660
15703371
16581787
16697054
17088286
17116881
17303408
17713585
19208614
19364882
19772495
19847258
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9488723
|
PARP1
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
71.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15211575
15385537
15385968
15498778
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19654615
19748837
19847258
19892829
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24089143
24095737
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
PARP1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PARP1
|
H2AFX
|
â—¼ PROTEIN_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
12607003
14726013
15175241
15459660
15703371
16581787
16697054
17088286
17116881
17303408
17713585
19208614
19364882
19772495
19847258
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9488723
|
PCNA
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
WRN
|
â—¼ SHARES_COMPLEX
|
|
|
71.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15211575
15385537
15385968
15498778
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19654615
19748837
19847258
19892829
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24089143
24095737
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PARP1
|
WRN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
71.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15211575
15385537
15385968
15498778
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19654615
19748837
19847258
19892829
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24089143
24095737
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
TOP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
20875401
15911331
15848144
14699148
15247263
|
PARP1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9312059
17891139
15044383
12898523
14627987
16713569
9565608
|
ABRAXAS1
|
PIAS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
PIAS4
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
POLD4
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD4
|
POLD1
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD1
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD1
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
E2F4
|
POLD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17531812
11799067
|
POLD1
|
POLD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
9286699
12403614
16510448
|
POLD1
|
POLD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
12403614
16510448
|
POLD4
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD3
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD3
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD2
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD3
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
PCNA
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD4
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD2
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
PCNA
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
PCNA
|
POLD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24022480
9038370
16510448
|
ABRAXAS1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
H2AFX
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
73.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20051983
20064462
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
TOP3A
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
XRCC5
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
XRCC6
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
WRN
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12202749
12607003
15140942
15211575
15385537
15459660
15498778
15964794
16163361
16449207
17055429
17116323
17303408
17965729
18087292
18171986
18398454
18524993
18558713
18584027
18809224
19202191
19362533
19490890
19654615
19772495
19793801
19892829
20027199
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
9721205
|
RAD50
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RAD50
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
H2AFX
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
73.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20051983
20064462
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
WRN
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12202749
12607003
15140942
15211575
15385537
15459660
15498778
15964794
16163361
16449207
17055429
17116323
17303408
17965729
18087292
18171986
18398454
18524993
18558713
18584027
18809224
19202191
19362533
19490890
19654615
19772495
19793801
19892829
20027199
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
9721205
|
H2AFX
|
RAD50
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
73.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20051983
20064462
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
RAD50
|
MRE11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19197236
16163361
10888888
8756642
17713585
|
PCNA
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
H2AFX
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
SEM1
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
24076221
22593209
14527420
23509288
24509834
18957201
|
RAD51
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD51
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD51
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD51
|
RAD52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
PCNA
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
H2AFX
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
RAD51
|
XRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD51
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD51
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD51
|
RAD52
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
TP53
|
RAD51
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17513613
16322760
20802511
16398215
18769160
|
E2F4
|
RAD51
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11799066
20133863
21701264
17531812
17001309
|
XRCC3
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9660962
23438602
28864920
11842113
|
TP53
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
8617246
11002423
16713569
16322760
16983346
9380510
|
RAD51AP1
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
21307306
21903585
16920159
9396801
20871616
17996711
|
RAD52
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
15766559
17145710
9826763
20190268
17118963
10666456
12750383
9837724
19338310
10448035
10212258
|
XRCC2
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
RAD51D
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
RAD51B
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
RAD51C
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
RPA2
|
RAD52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
11571269
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17582221
17884153
18677104
19473888
19772495
19793801
19809470
19847258
20081207
|
BARD1
|
RAD52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
XRCC3
|
RAD52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD52
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RPA2
|
RAD52
|
â—¼ PROTEIN_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
11571269
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17582221
17884153
18677104
19473888
19772495
19793801
19809470
19847258
20081207
|
XRCC3
|
RAD52
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BARD1
|
RAD52
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD52
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
WRN
|
RAD52
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17145710
12750383
12919958
17118963
|
WRN
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
TOP3A
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
RNF8
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
RNF8
|
ABRAXAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
RNF8
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
RNF8
|
TP53BP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
18001824
18006705
19203579
19772495
|
RNF8
|
H2AFX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
15496928
15549137
15655342
17303408
17660363
18001825
18006705
18171670
18212739
18583988
18590585
18678709
18678890
18809224
19217833
19270065
19490890
19772495
20021983
20064462
7575488
9407949
|
RNF8
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19772495
7575488
18590585
17303408
18001824
18678890
18583988
18001825
18678709
12607003
9407949
17660363
18006705
15279786
15459660
|
RNF8
|
UBE2N
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20023648
21911360
22589545
25909880
16215985
24732096
18678647
26285145
23255131
22814251
19549727
|
RPA3
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
TOPBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA2
|
RPA1
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
TOPBP1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA1
|
TOPBP1
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA1
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17145710
14499497
24126761
24332808
10373438
15735006
15965237
26474068
14734561
|
RPA2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
RPA2
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
TOPBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA2
|
PCNA
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
RPA2
|
RPA3
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
TOPBP1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA2
|
TOPBP1
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA3
|
TOPBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA3
|
TOPBP1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
RPA3
|
TOPBP1
|
â—¼ REGULATES
|
✅
|
|
43.0
|
1.0
|
ACSN
|
10884395
11877377
11900249
12086603
12648680
12766152
12875843
14624239
14726013
14988723
15136767
15175241
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17141802
17296725
17303408
17384638
17493829
17582221
17884153
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19809470
19847258
20051983
20478261
8943031
9524127
|
E2F4
|
RPA3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17531812
11799066
|
MRE11
|
TOP3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
TOP3A
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
E2F4
|
TOPBP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17531812
15195143
|
ESR1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20080630
16115928
22787161
12750288
20696891
17681750
17699779
|
RELA
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18269916
10348347
11032029
8051093
20061391
15155458
21332394
9890939
21887328
|
NFKB1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10348347
11032029
8051093
12145335
20097177
|
TP53
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10321841
7915517
15358233
12217864
10516009
1705714
8570655
16980608
9707425
15950182
19789303
11313928
1356162
12384701
9858527
12947108
23390122
8524244
9651310
1352831
7909518
11032828
10910968
12485898
10618724
|
UBE2D1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15169778
15340381
15147722
12820959
10722742
19459846
18006823
10721693
19440234
|
TP53BP1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
25579814
12110597
25837623
16713569
14978302
22653443
26022179
27546791
8016121
12351827
15611139
15364958
14985081
19433796
17805299
25651062
11877378
17634560
22084066
20307547
|
WRN
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12080066
11399766
15735006
16713569
11427532
|
AURKA
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
50.0
|
1.0
|
Omnipath
|
24173284
22864622
25217103
24089029
16713569
19413330
25848977
17999753
23565200
25333414
23201157
16552184
10884347
1956339
26186194
29455673
15469940
15749021
18974145
21502403
17287340
28043820
22396649
92065884
12198151
27933271
22852086
12064478
30266789
25398437
17259342
22350019
25634113
14702041
|
AURKB
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
20959462
27933271
20847049
15469940
32873634
22611192
27496712
|
PIN1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
12397362
12388558
17906639
12397361
21741598
16713569
24982848
21900206
|
UBE3A
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
23040663
7724550
9450543
16713569
16493710
15001357
17131388
9143503
19364824
31971989
11027293
9688277
9369221
1661671
7708685
12620801
8090726
8380895
26789255
|
TP53
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
18172499
18695251
24667498
22056774
17290220
17592138
12421820
18413597
20173098
19556538
21857681
17470788
18359851
19805293
19196987
12640129
|
TP53
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
12080066
11399766
15735006
16713569
11427532
|
XRCC5
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
XRCC6
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
TP53BP1
|
ABRAXAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
TP53BP1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
UBE2N
|
TP53BP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
17349954
17652783
18196958
19203579
19258535
19793861
19793862
19841479
19851286
22771115
|
TP53BP1
|
UIMC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
TP53BP1
|
BARD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
H2AX
|
TP53BP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17145710
20075863
18001824
21317870
12447390
17024177
18001825
21566653
12607005
12697768
21623170
|
AURKB
|
TP53BP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
28415769
|
UBE2D3
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10329681
|
UBE2D3
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10835356
|
XRCC6
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
XRCC5
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
UBE2N
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
UBE2N
|
ABRAXAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
UBE2N
|
PCNA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
10880451
16224103
16518696
17652783
18157158
18196958
18525240
18647995
19217833
19258535
19851286
20675655
|
UBE2N
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
18772547
12820959
18525240
19459846
19258535
19440234
17652783
15147722
10880451
15169778
19851286
10722742
18647995
18006823
18157158
16224103
20675655
16518696
18196958
15340381
10721693
|
MRE11
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
BARD1
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
H2AX
|
UIMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
BARD1
|
UIMC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11877377
15459660
16697054
19342239
19772495
19793801
19847258
20029420
21060331
21337561
|
MRE11
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
PCNA
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
10858306
11283614
11585362
11756412
11948190
12202749
12637553
14624239
14726013
15385537
15703371
15871698
16216273
16442856
16449207
16697054
17055429
17116323
17426133
17599061
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19748837
19847258
20027199
20056333
20064462
20691907
20713526
20955519
21376743
21727086
2191300
21922195
22021614
22455312
22657828
22743550
22973052
23082994
23110144
23161013
23253856
23414611
23485469
24036544
24050180
24709898
9407949
|
WRN
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
PCNA
|
WRN
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
10858306
11283614
11585362
11756412
11948190
12202749
12637553
14624239
14726013
15385537
15703371
15871698
16216273
16442856
16449207
16697054
17055429
17116323
17426133
17599061
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19748837
19847258
20027199
20056333
20064462
20691907
20713526
20955519
21376743
21727086
2191300
21922195
22021614
22455312
22657828
22743550
22973052
23082994
23110144
23161013
23253856
23414611
23485469
24036544
24050180
24709898
9407949
|
WRN
|
TERF2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
36.0
|
1.0
|
ACSN
|
11283614
12202749
12545156
15155580
15385537
16449207
17055429
17116323
17550342
17965729
18398454
18524993
18558713
18584027
18809224
19490890
20027199
20064462
20691907
20713526
20818389
21376743
21733352
2191300
21919891
22657828
22743550
23082994
23140366
23161013
23253856
23869868
24036544
24050180
24709898
9618481
|
TERF2
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17145710
15665826
18212065
12181313
|
BARD1
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
XRCC3
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BARD1
|
XRCC3
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
XRCC3
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
XRCC5
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
XRCC5
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
XRCC6
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
XRCC6
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
BARD1
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BARD1
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
PCNA
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
PCNA
|
H2AFX
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
PCNA
|
POLD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
H2AX
|
ABRAXAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
MRE11
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
MRE11
|
ABRAXAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
18077395
17525340
18001825
18001824
18006705
|
TNKS
|
AXIN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17825467
21799911
22154485
19759537
|
E2F4
|
AURKB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17531812
15033491
|
NFKB1
|
NFKBIA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
1829648
21725609
23178297
23572150
8096091
|
RELA
|
NFKBIA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
18204072
17876798
24083678
15499023
25759022
23422506
12859951
7775482
11744993
22723832
23450368
11060311
12885753
18981184
9250151
|
NFKB1
|
NFKBIA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17876798
15499023
17709515
7775482
11744993
10454561
11060311
12885753
9250151
|
NFKB1
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
61.0
|
1.0
|
Omnipath
|
17145710
25609649
7862124
1340770
16210649
16970925
21719482
9738011
9865693
10497169
8657102
9572494
9315679
21988832
8887676
10329681
1829648
14743216
17003112
11313474
20558726
26496610
7867065
7891711
10837071
7831327
15836773
26186194
11571291
15214841
17561400
16846590
9566883
8096091
15371334
7479976
11020244
9426183
16493424
15145317
8631829
20237821
20980497
16513645
9597130
7479848
7739549
7628694
10655476
|
UBE2E3
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9409737
10187858
10582246
16713569
9734360
|
RELA
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
134.0
|
1.0
|
Omnipath
|
17145710
15657065
11801607
25609694
15226358
17003112
9057089
26496610
19219072
23850221
7831327
12927781
16683270
17301240
17561400
9566883
10391945
8887633
16209943
21719482
10066434
8657102
10581242
29734393
21988832
12419806
14743216
16105840
15671248
9751059
9990853
25759022
10498867
8246997
7878004
11020244
9426183
15845455
26476452
23563313
16951195
25520503
9694722
11287411
10329681
15799966
17612295
24457201
10085161
10837071
10969074
11571291
9573251
15214841
16846590
20065107
7479976
24248593
8887627
15145317
16493424
9135156
24634218
7479848
15024091
14636585
26463447
7862124
1340770
22081069
8139561
27923823
16970925
9738011
9865693
9572494
11231305
14685242
20797629
11313474
16226509
14690596
22022389
21217772
26186194
30213788
15371334
8978697
20980497
7739549
7628694
|
UBE2D2
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
10329681
|
TNKS
|
TERF2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
17825467
21181822
21818122
22433952
22634377
9822378
|
AURKB
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
11278789
19007248
17938195
10464286
16457588
12234980
12082625
21282660
15249581
10949293
15108802
16185088
14583461
12588998
15681610
17924679
16222246
15684425
12560483
11856369
|
NFKB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RELA
|
TRAF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19343319
17673602
14991743
19383900
17018379
9733827
9733516
10823821
11297551
|
RELA
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16778171
20427719
23362108
16513645
1740105
20596645
16513841
19469019
8454856
21420936
16135789
9417120
|
NFKB1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16209943
25609649
8428580
12947093
16970925
17072323
2050119
15657065
21270162
11976329
16793322
21544861
22261743
8657102
9824778
11880271
9450761
17962807
21988832
25355951
9722548
18215660
14743216
15799966
10799898
16105840
15218526
8798655
14690596
22139845
22808155
11571291
17072327
16740634
10498867
8255759
8246997
15214841
16846590
15371334
16285893
17072322
17855547
18321863
16493424
7479976
15145317
17561400
20110362
9426183
23687337
12414801
11970949
20154269
20237821
24175631
24634218
34100597
14645533
17982102
21763497
16204234
9437432
20547752
15818410
7628694
|
SKP2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
19847258
19686080
19270156
17884153
19622404
15703371
11237742
12648680
11900249
16697054
18931676
19809470
15459660
|
NFKB1
|
TRAF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19343319
17673602
14991743
17018379
9733827
9733516
10823821
11297551
|
TNKS
|
TERF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
23583392
12080061
20811636
26186194
11854288
11739745
22153077
10988299
15133513
20696165
22645305
26496610
11802774
9822378
|
AURKA
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
14583461
15108802
17938195
15249581
12234980
12588998
12082625
|
AURKA
|
TACC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15630414
17145710
14602875
14603251
15064709
|
CSTF2
|
CSTF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
24149845
10357856
10669729
10371034
|
SETDB1
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21243721
11791185
11252719
11959841
|