Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ESR1 ARHGDIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21447808 11060289
ENSA ARIH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
NFKB1 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9294162 9733516
TP53 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16917513
BRCA1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 12700228
RNF7 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23136067 17217622
PIN1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 9499405
RNF7 CDC34 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10851089 16874460
TRIM39 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
DTX1 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
LNX2 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CTNNB1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983094 0606850103
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 STMN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17273793 16712787
MCTS1 DENR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
EIF1AD RPS17 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EIF1AD LRRC47 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NFKB1 ELF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12746898
ESR1 MAP3K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15556606 5217326
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
UBB HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPA8 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RNF11 ING4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 ING4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217105 15251430
ING4 TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
KLC1 LRSAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LRRC47 RPS17 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MAP3K1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23109003 15032589
UBB MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP3K1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10085121
RFWD3 MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0912094107 20173098
RFWD3 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20173098
PAFAH1B2 TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
PAK3 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
TP53 PARK7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23447676 23149933
PPM1A SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16751101 8277589
PSMD9 TRIM39 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
RANBP1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12649209 5216249
RNF10 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RBCK1 RNF31 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
RCHY1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 5220017 17568776
TP53 RFWD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0912094107 20173098
RNF11 RNF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF14 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBE2D4 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF126 UBE2D4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RNF8 RNF168 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20385750
SMAD2 TRIM62 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBE2Z SRA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STIP1 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2L3 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
TP53 TOPORS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219611 17290218
TRIM39 TRIM17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBTD1 TRIM39 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRIM39 UBE2D4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ARPP19 PCNP â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CRK PFN1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
STUB1 UBE2D4 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
DENR PSMD9 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RNF13 UBB â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
MCTS1 RPS17 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
NUBP1 NUBP2 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ARPP19 SZRD1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
TRIM25 UBB â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
RLIM UBB â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
DENR MCTS1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
AMFR UBB â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
MUL1 TP53 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
TUBB2A TUBB4B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
ARMC6 MUL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UBXN1 BIRC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25681446 18775313
FSD1 DENR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ESR1 NACA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
FSD1 LZIC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FSD1 MCTS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RNF26 NAA50 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PARK7 PPIA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31536960 29128334
TRIM25 UBE2D2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ESR1 STUB1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
UBB ZRANB1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
RNF31 UBB â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
TUBB2A TUBB4B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RNF126 UBE2D2 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
EIF4H SZRD1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
GSPT1 RPS17 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
GMFB PPM1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
FSD1 CHAC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VPS4B BIRC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BIRC2 RNF31 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24726327 27545878 30561431 23524849
BTF3 RPL38 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
FSD1 PAK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FSD1 UBFD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STUB1 HSPA8 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16293251 5218068
RLIM UBE2D2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CTNNB1 SIAH1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
AMFR UBE2D2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
PFDN1 PFDN5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
GSPT1 RPL38 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
TUBA1B TUBB4B â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
BIRC2 UBB â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
RNF168 UBB â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EIF5A PFN1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
UBE2L3 ARIH2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24076655
SMAD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11555647 20207742
TP53 PIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 12397362 5215850
HYPK NAA50 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
MDM2 UBB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PFDN1 PFDN6 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PFDN6 VBP1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
VHL PDCD5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24469044 17353931
NUBP1 NUBP2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RANBP1 UBE2L3 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CACYBP CTNNB1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
DENR RPS17 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
PFDN5 VBP1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
BIRC3 CASP3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17069460 9384571
RCHY1 UBE2D2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
UBB RNF11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 14755250 33961781
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
VBP1 VHL â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
AMFR UBE2G1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CASP3 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TUBB TUBB2A â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TUBB3 TUBB4B â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
RNF4 UBE2D2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PAK2 PAK3 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
ELF3 NFKB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11036073 23687337
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ING4 TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
PIN1 SMAD2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19920136 19122240
TOPORS TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
TUBB TUBB2A â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
RNF31 UBE2L3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PFDN2 VBP1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
RCHY1 TP53 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ARIH2 UBE2L3 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
CCNB1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9244350 16713569 23246971 11278247
MDM2 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897156 17545634 10766163 11178989 16713569 31012223
TP53 RCHY1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 17568776 5220017
TP53 RCHY1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 17568776 5220017
CDC34 UBB â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PFDN2 PFDN5 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
RNF13 UBE2D2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
ACP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16287083 12438242
ARHGDIA UBE2R2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NFKB1 BIRC2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 21725609 23178297 23572150
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CASP3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12149654
BRCA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17873885 11320250 14636569
CASP3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9348292
EIF5A DOHH â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 17213197 16533814 14622290
ESR1 F12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9794469 11459781
HSPA8 PARK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
RFWD3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20173098
TP53 TPT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14623968 24067374 22157679
UBE2L3 UBE2V2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
UBB UBE2V2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
UBB UBE2D2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PFDN2 PFDN6 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
NUBP2 NUBP1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 33961781 22863883
TUBB TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TUBA1B TUBB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
RNF115 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
SMURF1 UBE2L3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
PFDN5 PFDN6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
TUBA1B TUBB2A â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
STMN1 STMN2 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
RPS17 TPT1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
TUBB2A TUBB3 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
UBE2D4 UBTD1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
HSPA8 STUB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
PTEN SPOP â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
RPL38 TPT1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
TUBA1B TUBB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
RNF11 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
RAN RANBP1 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
NACA BTF3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 24981860 26344197 21203952 30948508 33644029 10982809
TUBA1B TUBB2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
STUB1 UBE2D2 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CACYBP SIAH1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BIRC2 UBE2D2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RNF25 UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RNF31 UBE2D2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
BIRC3 UBE2D2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RNF31 RBCK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219147 17006537
MDM2 UBE2D2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CNOT4 UBE2D2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
BTF3 NACA â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL38 RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
HSPA8 STIP1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
NUTF2 RAN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PFDN1 PFDN6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 VBP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 PFDN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 PFDN5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DENR MCTS1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 VBP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 PFDN6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN6 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFKB1 BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15050749 17673602 12687011 15756023 9733516 12010810 18566231 16453001 20103608
BIRC2 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 9990849 12042762 9384571 17069460 11382748 11106668 16189514 11084335
NFKB1 BIRC3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21725609 23178297 23572150 9294162 9733516
NFKB1 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15231833 15050749 19343319 17673602 17000776 11880364 10733571 9733516 18566231 12010810 15723831 10823821 11297551
BIRC3 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9990849 12042762 9384571 17069460
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
CASP3 DFFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11406587 25241761 12655299 18723680 9786842 9422513 9422506 16189514 9108473 11752060
CASP3 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9712143 9171063 11070003 9786869 16204230
CASP3 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 9278461 21726810 24842904 9840926
TP53 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12874009 14627709 10051609 11313928 17942917 11892838 15710382 20395210 19470724 12379461 11071927 11522645 15737644 11162602
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
SIAH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 28481365 11389840 32671611
PIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 11533658
MCTS1 DENR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17878526 16169070 32296183 21516116
DTX1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15684388
ESR1 EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10894157 15075211 20889718 8770893 19423651
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19805293 22056774 17290220
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
PEX5 UBE2D2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21554508 19208625 17726030 18359941 10562279
PIN1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12397362 12388558 17906639 12397361 21741598 16713569 24982848 21900206
PPM1A SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18988627 16751101 23331499
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
RANBP1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 11832950 12649209 9111043 10811801 7603572 9315840 20805321 7891706
RBCK1 RNF31 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
RBCK1 RNF31 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
RCHY1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 21988832 19483087 17568776 24367557 25116336 21084285 12654245 21791603 20452352 19043414 16713569 31630802 27519799 19918835
TP53 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20181957 20421190 14985507 11852084
TP53 SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12077306 12438652 14985507 15326481
SMURF1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10458166 23331499 15221015 20207742 15231748
TOPORS TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17803295 17290218 11842245 16713569 15247280 10415337 19473992 16122737
TP53 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18172499 18695251 24667498 22056774 17290220 17592138 12421820 18413597 20173098 19556538 21857681 17470788 18359851 19805293 19196987 12640129
VHL UBE2D2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499