Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

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Layout:
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Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
ASCC2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
BAK1 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 COPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 CSTA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ERCC6 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 EYA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAM2 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GGA3 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15611048 5217420
HGS UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HGS VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS GGA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15611048 5217420
HGS NEDD4 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 12230472 5215741
MYO6 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBC IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
PSMD13 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIPK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10880512 5212735
TBK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS15A IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNFAIP3 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11389905 5214127
UBB IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYO6 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKG RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 ING4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BECN1 ING4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22081109 8303868
RNF11 MNAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYO6 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBC NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
RNF11 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11689694 5214752
OTUB1 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 BRK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 RNF168 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21130715
PSMD2 PSMD4 â—¼   COLOCALIZATION 2.0 0.8 intact 16990800 5219132
RNF11 RBM14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RNF138 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OPTN SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TDG SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TDG RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D3 GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DZIP3 UBE2E2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
ANKRD13D UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RNF11 UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBQLN2 UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
YWHAQ UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
UBQLN4 STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
WWP2 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
UBA52 USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
RPS27A USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
USP7 UBA52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 26235645
USP7 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 26235645
H3C2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
RNF11 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAQ YAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12535517 5216053
RNF11 GPANK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OPTN GPANK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 LCE1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D1 GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22842904 21857666
RNF11 KRTAP8-1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VSX2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D4 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PLEKHG7 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ANXA8 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NGEF RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TCEAL8 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BECN1 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZFYVE16 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ZXDC RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALCOCO2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF14 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TMEM61 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNRNP70 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBA52 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
IQUB RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZNF57 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZFYVE9 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
FOSL1 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BAP18 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR1D2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LPIN1 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPATA8 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CLIP3 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
QARS1 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBQLN2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TAX1BP1 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TASOR2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATG10 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HK3 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
KLHL20 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
METTL27 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WDR83 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF15 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LNX1 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ASB13 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BSND RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LOXL4 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MPND RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LHX8 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 H3-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 GGA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 RNF216 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 CXorf38 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 AUP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 ZNF366 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 ZNF524 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 FAM117B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 HOXC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RABGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 SPSB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 GOLGA2P5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 GFOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 DPYSL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RNF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 WDR61 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 VDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 SPRY4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 TSC22D4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 PRKAA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 FAM98C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 ESRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 GGA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 EPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 SPSB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 IQCF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 TENT5B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 TIMM17B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 TOLLIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 SDC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RNF208 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RNF112 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 ASCL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 PSMB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 SYT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RPS15A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RNF183 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 PCMTD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 BRK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 KRT33B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 LHX6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 DCUN1D1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 SH3KBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RUSC1-AS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 G6PC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 C8orf48 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 CNPY3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 AQP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 ZNF497 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 PDCD6IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 WDR77 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 TBPL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 GPR141 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 PSMB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 ITCH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8012720 20676133
RNF11 ZNF670 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 C7orf31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 PLEKHG7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 GPSM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 SAMD7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 FABP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 TEX19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 SNAPC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 ATP6V1B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RYBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 UBAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 OPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 CYB5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 DMRTA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 UBE2E3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 ARFGAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 TRIM21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 KRTAP19-7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 FAM163A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 ZNF296 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 ZKSCAN8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 PRPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 ESM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 TNIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 TLE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 KCTD13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 TOM1L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19131965 23010170
RNF11 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19131965
GNB2 UBE2D4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CSNK2A1 CSNK2B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
OPTN RNF112 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OPTN ASCL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OPTN C8orf48 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OPTN TNIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TNFAIP3 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20501938
RYBP UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB STAMBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB USP5 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 7851534
USP5 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26235645 16007098
KCTD13 LNX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PSMD11 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNRNP70 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD4 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
SMAD4 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12099698 15242331
SDCBP RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
RIPK1 PDCD6IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
TNFAIP3 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19131965 20599425
TAX1BP1 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19131965 23010170
SMURF1 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 17317136
VAMP3 STX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
AP2S1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
UBC SMURF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
SNRNP70 SMURF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
AKT1 USP14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26523394
UBC TNFAIP3 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
PSMD8 PSMD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
PSMD4 PSMD12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
TLE1 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ATG10 GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D2 GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2O GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 UBE2O â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 UBE2G1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WWP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
WWP2 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
UBC TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
USP2 UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
STAMBP UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBC USP5 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBC USP5 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 7851534
RNF112 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZNF366 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WDR61 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MPND APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CSNK2A1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LNX1 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LNX1 TSC22D4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EPS15 EPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6179743 18200045
STAMBP STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
STAM2 VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
RYBP BRK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VDAC2 BRK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SDCBP PDCD6IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
TLE1 RNF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ESRP1 SDC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAQ WDR77 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
UBC UBQLN4 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
CBLB UBB â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
NEDD4 AKT1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19953087 23195959 31390487
UBE2D1 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8379996 22124327
NEDD4L UBE2D3 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
ITCH RPS27A â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
RPS27A WWP2 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
RPS27A TRIM21 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
TRIM21 UBB â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
ERCC6 RPS27A â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ERCC6 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
UBA52 USP5 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
RNF216 UBE2L3 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
OTUB1 UBE2D1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
OTUB1 UBE2D3 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
MYO6 EPS15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26950368 29467281
MYO6 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26950368 11967127
YAP1 STAT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 22863883
RNF11 UBC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20676133 15231748
OPTN EPS15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31723608 17626244
AP2S1 UBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MYO6 UBB â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
LNX1 UBA52 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
GPANK1 METTL27 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
LNX1 RPS27A â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
RPS27A STAMBP â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
LNX1 UBB â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
TNFAIP3 UBB â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
LNX1 UBC â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
UBAC1 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
WDR83 SNW1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
UBB UBE2D1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
RNF11 QARS1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217094 15231748
RNF11 EPS15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24377927 23222715 14755250
RNF11 GGA3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25195858 15231748
RNF11 SOAT1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 31985874
RNF11 WWP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 16713569 28292929 31985874 32814053 15231748
WDR83 UBB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
EPS15 STAM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 12551915
PSMD10 PSMD8 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
SH3KBP1 UBB â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
OPTN RIPK1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
TOLLIP UBC â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
UBC HGS â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 12750381 5216384
GGA2 GGA3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14638859 31076515
TRIM21 UBE2D2 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
GGA3 UBB â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
STAM2 UBB â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
UBB USP5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
OTUB1 UBE2V2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RNF168 UBB â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
OPTN MYO6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20161783 26971995 19805065 15837803 26451915
RNF11 STAM2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 24377927 32814053 23222715 15231748
UBC PSMD4 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5220924 8570649
RNF168 UBE2D3 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TRIM21 UBC â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ERCC6 UBC â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
UBC UBQLN2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
GGA1 GGA2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
NEDD4 SMURF2 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
BECN1 NEDD4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28128446 29251248 21936852
PSMD2 UBQLN4 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
SNW1 XRCC6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20467437 30585729
RNF11 UBE2N â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23751493 28292929 19690564 19549727 31985874 18615712 15231748 29537486
RNF11 WWP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 16713569 28292929 31985874 15231748 18724389
LNX1 UBE2D2 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
CALCOCO2 TBK1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
YAP1 YWHAQ â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
MYO6 RPS27A â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
GGA3 RPS27A â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
USP5 UBC â—¼   CLEAVAGE ✅ + 0.86 0.86 Signor 26235645
RPS27A USP2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
STX4 VAMP3 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
NEDD4 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD1 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMB4 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMB4 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
NEDD4L UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD11 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD7 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD12 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD8 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD11 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD12 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD7 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD8 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
EPS15 AP2M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24189400 33961781 26186194 19380743
HGS GGA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15611048 19019082
UBE2D3 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8379996 22124327
PSMD1 PSMD10 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
PSMD5 PSMD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19589775 19490896 33961781 22939629
PSMD5 PSMD3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26344197 19490896
UBB RNF11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 14755250
UBAC1 UBB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
EPS15 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 19380743
AP2A1 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 26344197
EPS15 AP2S1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 19380743
PSMD5 PSMD6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26344197 19490896
PSMD5 PSMD8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26344197 19490896
IKBKE TBK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
NEDD4 UBA52 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
LNX1 UBE2N â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
UBA52 USP7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PDCD6IP SH3KBP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RABGEF1 UBA52 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CALCOCO2 UBC â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PSMD1 UBA52 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PSMD3 UBA52 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
UBA52 UBE2V2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PSMB4 UBA52 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PSMD8 UBA52 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PSMD7 UBA52 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PSMD11 UBA52 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
UBA52 USP14 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MYO6 TAX1BP1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ITCH UBE2D3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
UBE2D3 WWP2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
NEDD4L UBE2D1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
UBA52 UBE2D1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PSMD12 UBA52 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
UBA52 UBE2D2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CBLB RPS27A â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
TAX1BP1 UBC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HGS NEDD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 12230472 23602387 25588945 20675381
OPTN UBB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31723608 22101367 23414517
BECN1 AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29669822 23112296 28628118 28205554
SMURF1 SMURF2 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
PSMD4 UBC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19796170 8570649 20059542 9488668 19798103
TNIP1 UBC â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
NEDD4 PSMD4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ATP6V1B1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
IKBKG TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
IKBKG TNFAIP3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
OTUB1 UBE2D2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
OPTN ZNF670 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
TNFAIP3 TNIP1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
EPS15 HGS â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
TENT5B UBQLN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
UBB USP2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AP2A1 AP2B1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AP2M1 AP2S1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 EPN1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
UBE2D2 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8379996 22124327
PSMD1 PSMD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22863883 22939629 26344197
PSMD2 PSMD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22863883 33961781 22939629 26344197
PSMD2 PSMD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25036637 33961781 28292943 22939629 26344197
ITCH RNF11 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28292929 19131965 31985874 20676133 22507528 14559117
RNF11 GGA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20676133 15231748 25195858
RIPK1 TNFAIP3 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
AP2S1 AP2B1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 12086608 16189514 33961781 34079125 26344197
TAX1BP1 TNFAIP3 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
EPS15 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10764745 19380743 10953014 8662627 9049247
GGA1 GGA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14638859 33961781 28514442
NEDD4 UBE2E1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
UBC UBE2D3 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PSMD10 PSMD6 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RNF168 RPS27A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
HGS RPS27A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
UBC WWP2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ITCH UBC â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
TNFAIP3 UBE2D1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AP2B1 AP2M1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12086608 16189514 16713569 24189400 33961781 19380743 26186194 30021884 34079125 26344197
EPS15 HGS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12551915 27008177 18362181 10809762 10514494 15772161
HGS UBC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12230472 12207904 11916981 12750381
HGS ZFYVE9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 11094085
TNFAIP3 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18353649 15661910
H3C2 ING4 â—¼   ACETYLATION ✅ 3.0 0.9 Reactome 18381289 18623064 19187765
OTUB1 UBE2N â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24071738 30718280 32049508 22367539 25872870 26752685 27173435 27909234 19615732 20725033 22679021
PSMD1 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PSMD2 PSMD5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 10625621 19490896 33961781 22939629 26344197
UBE2D3 UBA52 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSNK2B TLE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TBK1 OPTN â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 18307994 6492190
TNIP1 OPTN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 25416956 21988832 25910212 33545068 33961781 23414517 21516116 26871637 30561431
OPTN TBK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27086836 25923723 32556086 29395067 27035970 27538435 25803835 26365381 20174559 27620379 30327196 23414517 18307994 31723608 32707033 21903422
STAT1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19508864 9841227
AKT1 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 23397142
ACVR2A SMURF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
VAMP3 STX4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16189514 25416956 10820264 34079125 12130530 12828989
ACVR2A SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
BMPR2 SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
TNFAIP3 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18353649 15661910
CSNK2A1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14675149 25862939
TBK1 CALCOCO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19820708 21903422
ACVR2A ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
BMPR2 ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
NEDD4 UBE2D1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SMURF2 UBE2D3 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
AP2A1 EPS15 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PSMD3 UBC â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PSMD3 UBB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
UBE2L3 UBE2V2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PSMD14 UBA52 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
RPS27A STAM2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
ITCH UBE2D2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
RPS27A SMURF2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
UBB UBE2V2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
PSMD1 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PSMD3 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
RPS27A UBE2V2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
RPS27A UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
UBAC1 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
UBB UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PSMB4 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PSMD12 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PSMD7 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PSMD8 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PSMD11 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
UBB UBE2D2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EPS15 UBC â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
NEDD4L UBE2L3 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
TNIP1 TNFAIP3 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 5214127 11389905
RPS27A UBE2D1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PSMB10 PSMD5 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CBLB SH3KBP1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PSMB10 PSMD4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
SMURF1 UBE2D3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
SMURF1 UBE2L3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
SMURF2 UBE2L3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
PSMD14 PSMD7 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
SMURF2 UBC â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
PSMD10 PSMD11 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PSMB10 PSMD6 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EPN1 EPS15 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
UBA52 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
RNF208 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
GGA1 UBC â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
PSMD1 PSMD2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 22863883 33961781 28292943 22939629 26344197
PSMD1 PSMD3 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 22863883 33961781 28292943 22939629 26344197
PSMD10 PSMD12 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
PSMD2 UBA52 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
IKBKG RIPK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
NEDD4 UBE2D2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
NEDD4 UBE2D3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
NEDD4 UBE2L3 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PSMD14 RPS27A â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PSMD2 RPS27A â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PSMB4 USP14 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
RPS27A USP14 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
AP2B1 EPN1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 34079125 22863883
STAMBP UBC â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
TRIM21 UBE2E1 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
UBE2L3 WWP2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
RNF11 UBE2D1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
RPS27A SH3KBP1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
UBE2L3 WWP1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
IKBKG UBC â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
RPS27A TNFAIP3 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
TRIM21 UBE2N â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PSMD10 PSMD3 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
PSMD10 PSMD13 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
SH3KBP1 CBLB â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6170278 12177062
PSMD5 PSMD4 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22921402 33961781 19490896
PSMD10 PSMD7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
UBB USP7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
RABGEF1 RPS27A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RABGEF1 UBB â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PSMD2 UBB â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
OTUB1 UBC â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
PSMB4 PSMD5 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RPS27A USP5 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
PSMD4 UBQLN4 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
RPS27A USP7 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
PSMD11 PSMD5 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RNF11 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
CBLB UBE2D2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
PSMD3 PSMD8 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 18775730 22863883 33961781 28292943 22939629 26344197
PSMD10 PSMD14 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
PSMD14 PSMD5 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
UBB UBE2N â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
RPS27A UBE2D2 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
PSMD14 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBE2N â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBB USP14 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PSMD2 UBC â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
HGS STAM2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 15113837 16713569 12551915 20504764 13679051 22939629 26344197 16429130
RNF11 NEDD4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28292929 19953087 31985874 11042109 20676133 15231748
PSMD4 PSMD1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 19781552 16990800 22863883 33961781 30479383 22939629 26344197
PSMD6 PSMD1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17353931 22863883 22939629 26344197
PSMD6 PSMD2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17353931 22863883 33961781 28292943 22939629 26344197
TNIP1 OPTN â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8153045 21516116
AP2S1 AP2A1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31353312 16189514 7593184 33961781 26344197
PSMD10 PSMD2 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PSMD10 PSMD4 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
RPS27A UBE2N â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PSMD5 PSMD7 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PSMD4 PSMD5 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HGS UBC â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MYO6 UBC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PSMD4 UBA52 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ITCH UBE2L3 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
UBC UBE2D1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
PSMD14 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
PSMD4 PSMD3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16990800 22863883 33961781 30479383 22939629 26344197
PSMD4 UBB â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
EPS15 EPN1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15809337 9723620 10791968 18200045 18375383 21115825 16429130
HGS STAM2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PSMD2 PSMD5 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PSMD3 PSMD5 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PSMD5 PSMD8 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PSMD1 PSMD5 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RNF168 UBC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PSMD12 PSMD5 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PSMD13 PSMD5 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SH3KBP1 UBC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
STAM2 STAMBP â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CBLB UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
PSMD5 PSMD6 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
UBC UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
OPTN UBC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PSMB4 PSMD8 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PSMD6 USP14 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GGA3 UBC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NEDD4L UBE2D2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PSMD4 PSMD2 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 17646385 30479383 25036637 24256120 16990800 22863883 33961781 24121268 22939629 26344197
CSNK2B CSNK2A1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 36833176
PSMD4 PSMD8 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 20542005 16990800 22863883 22906049 33961781 30479383 22939629 26344197
PSMD6 PSMD8 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 17353931 22863883 22939629 26344197
STAM2 UBC â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
OTUB1 UBE2N â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
OPTN TBK1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TNFAIP3 UBC â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
UBC USP14 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
NEDD4 UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NEDD4 RPS27A â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NEDD4L UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PSMD4 UBQLN2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
PSMB4 PSMD6 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UBC USP5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
UBC UBE2V2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBC USP2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
PSMB4 PSMD3 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
PSMD6 PSMD3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 18775730 17353931 22863883 33961781 28292943 22939629 26344197
PSMD6 PSMD4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 17353931 16990800 33961781 30479383 22939629 26344197
RABGEF1 UBC â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PSMD1 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD1 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD13 PSMD2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD2 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD13 PSMD3 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPS15A UBA52 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMB4 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
AP2B1 AP2S1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD4 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD12 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD13 PSMD8 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD13 USP14 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD13 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD6 PSMD8 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD3 PSMD6 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRKAA2 PRKAB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMD11 PSMD13 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMD11 PSMD6 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMD12 PSMD13 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PSMD14 PSMD6 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PSMD13 PSMD4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PSMD6 PSMD7 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMD13 PSMD14 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB10 PSMB4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB4 PSMD11 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMD13 PSMD7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB4 PSMD7 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS15A RPS27A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMD4 RPS27A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMD4 UBC â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GTF2H4 MNAT1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB4 PSMD1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD1 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD1 USP14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB4 PSMD14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD14 USP14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD2 PSMD7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD2 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD2 USP14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD12 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD3 PSMD8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD3 PSMD4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD3 USP14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB4 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD4 USP14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD11 USP14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD11 PSMD8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD12 PSMD8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD12 USP14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD7 USP14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD8 USP14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD1 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD14 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD14 PSMD8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD14 PSMD4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD14 PSMD3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMB4 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD11 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD12 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
GTF2H1 MNAT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H1 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD11 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD14 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD12 PSMD14 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD11 PSMD14 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD2 PSMD8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD2 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD11 PSMD3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD3 PSMD7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UBC UBE2N â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMB4 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD11 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD12 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD4 PSMD7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD4 PSMD8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD11 PSMD12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD11 PSMD7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD12 PSMD7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD7 PSMD8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BAK1 VDAC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12881569 19706873 22039431 23430059 23850759
BAK1 VDAC2 â—¼   PROTEIN_INTERACTION 5.0 1.0 ACSN 12881569 19706873 22039431 23430059 23850759
VDAC2 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 22705850 17353931 12881569 16189514
TBK1 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 18353649 17327220 16858409
IKBKE STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24065129 17502367 24416652 29186193 24058806 22520844
IKBKE TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 17327220 24622840 16858409
RIPK1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
IKBKG STAT1 â—¼   DOWN_REGULATES ✅ - 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
AKT1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20837477 20098747 17660512
RIPK1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10880512 21383699 21458669 14653779 10980203 17702576 9927690 16603398 16547522 16965765 10755617
TNFAIP3 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 21988832 11389905 22099304 23032186 20932475 26802121 31585000 10755617
TNIP1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21988832 16684768 18212736 20010814
OTUB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22367539 21130715 24145445 21763684 35500217
XRCC6 RNF168 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 UBE2N â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
XRCC6 UBE2V2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
ITCH YAP1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157
AKT1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 27979972 25360797 26804165 28273460 25751140 24101154 25751139 34052254 25362852 28114269 28793266 26265440 31239271 25601544 28474680 33630828 26119935 27144834 27425596 25531778 34206989 34465890 21945154 25195862 31792377 18640976 28775168 32015438 32523092 22234184 33536280 33622361 30600590 24362629 34155345 24658687 21060948 33162394 20153295 26668327 21730131 26549256 21666719 25605730 26039999 34226698 20823509 34516278 27033705 32064037 32271880 32513743 33990468 24812269 32053631 32929029 34058200 25772246 26364602 27765911 26678338 27979971 33552953 28171658 34129887 21376238 28416665 25998128 25109332 12535517 31988076 26933062 26598551 25373897
AKT1 RNF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16123141
WWP1 RNF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 15231748 18724389
RNF11 ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14559117 19131965
CSNK2A1 CSNK2B â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TBK1 OPTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 27247382 29246869 29594070 27035970 21617041 18307994 22364875 29755463 21903422 26376340 29867991 23794264 26101267 26365381 21862579 27538435 25026213 25923723 29282133 29626651 29971063 30294276 30223576 20174559 26266977 23414517 27086836 23178947 22518139 27906974 25803835
STAT1 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
ITCH RIPK1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10940313 11318614 16469705 16861923 18552861 18628966 19131965 20068034 21107885 21383157
RNF216 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16968706 11854271 27995769
TNFAIP3 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20448643 17703191 18246070 15258597 19131965
CSNK2A1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 29732088 17374729 21506126 11689703 10671551 12149249 15818404 10747897 10837139 20976471 19662498 21285348 11035045 11707428 21735093 17444818 20558317 11972058 16707567
TBK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21329883 21464307 21106850
AKT1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
TAX1BP1 TNFAIP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18246070 34454289 20599425 23018911 32296183 10435631 18239685 11389905
USP5 UBC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 19285159 20622874 22878415 26235645 18482987 19373254 16007098 31663737 25970461 27848959 17550899 26876099 24681967 23314748 17980597 16564012 27066941 17692280 22428841 8841133 22216260 24424410 34648286
CSNK2A1 TLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22354967 15367661 20558317 20976471
EPS15 SH3KBP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
EPS15 EPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 16429130 18375383 35044719 9723620 10393179 18200045 15809337 21115825 10791968
STAM2 SH3KBP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251