Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
GPR35 CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
RNF11 AUP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
ESR1 ITGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
SEL1L FAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18711132 0805371105
VCP FAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18711132 0805371105
VCP FAF2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FAF2 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FNTB KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12374986 24294527
ITGA1 ILK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19397781 26148229
TCTN2 OPRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
UBC RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 UBE2E3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AMFR DERL2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
SEL1L VCP â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CANX RPN2 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
CLN3 AUP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23464991 20562859
AUP1 RPN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21857022 34079125
AUP1 TERA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21857022 29540532
AUP1 TP4A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
FAF2 SE1L1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22119785 18711132
RPN2 APOB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CLN3 RPN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23464991 20562859
CLN3 PRKDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23464991 20562859
EDEM1 DERL2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17360537 32423001
SEL1L OS9 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 29496332
RNF11 UBC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15231748 20676133
AUP1 RN114 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AUP1 F175B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AUP1 FNTB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
APOB TERA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19164805 18550891 28183703
FNTB TP4A1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AUP1 SEL1L â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
AMFR ERLIN2 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
FAM8A1 SYVN1 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
UBE2G2 AMFR â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 23942235
DERL2 OS9 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EP300 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33742100 30110629 20808282
GPR35 AUP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 28298427
SE1L1 AUP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22119785 21857022 18711132 28827405
AUP1 SYVN1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31056421 21857022 22119785 28827405
OS9 SE1L1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24899641 23356641 19084021 19346256 18711132 28827405 26551274 29496332 18502753 23867461 23097496 21454652 22119785 18264092
AUP1 UBE2G2 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
AUP1 APOB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26186194 28183703
ILK PRKDC â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25852190 23455922 32707033
DERL2 FAF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HSP90B1 OS9 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
UBC UBE2G2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
OS9 VCP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ERLEC1 SYVN1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
UB2G2 AUP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32296183 23223569 17353931 21127063 21857022 22119785
SE1L1 SYVN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23356641 18711132 26424800 28827405 32614325 31477895 29496332 18502753 24807418 23867461 24366871 26471130 21454652 16186509 21903092 22119785 18264092
CANX VCP â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
AMFR FAF2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
VCP DERL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21357747 23867461 19002207
SYVN1 DERL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21357747 23867461 19002207
FAM8A1 SYVN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28827405 22119785
FNTB HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15451670 24294527 2217184
ITGA2 ILK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11112697 25100717 9456329
PRKDC VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16140914
VCP SEL1L â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21357747 23867461 19002207
ERLEC1 SEL1L â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AMFR VCP â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
UBC VCP â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
DERL2 SYVN1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
DERL2 SEL1L â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
DERL2 VCP â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
FAF2 TERA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 26389662 18835813 23665563 29599191 18711132 22466964 34739333 22350894 25078495 22119785 29997244 18775313
TERA SYVN1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 16186510 16289116 20414249 26424800 17872946 24100225 26471130 16822850
OS9 SEL1L â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
FAF2 VCP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
OS9 SYVN1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SEL1L SYVN1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
AMFR UBC â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RPN2 STT3B â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
AMFR UBE2G2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
SYVN1 VCP â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
AMFR VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20126661 22328510 16407162 16987818 17681147 26712280 16275660 21636303 17872946 18835813 19828134 22119785 23333620 23383273 26424800 21343306 21914798 16186510 15331598 17311810
OS9 DERL2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19002207 21357747 18502753 18711132 18264092 23867461
VCP ERLEC1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19002207 21357747 18502753 18711132 18264092 23867461
ERLIN2 HRAS â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
ERLIN2 KRAS â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
ERLIN2 NRAS â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
VCP OS9 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19002207 21357747 18502753 18711132 18264092 23867461
SYVN1 SEL1L â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12847084 16186509 18199748 18360008 19509052
SYVN1 SEL1L â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12847084 16186509 18199748 18360008 19509052
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368