Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
PCNA REV3L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19806028
TP53 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
POLI DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
POLI CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FAM189A2 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CALCOCO2 DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CALCOCO2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBB DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
POLI DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DAZAP2 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ERCC6 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ERCC6 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
JDP2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11287607 25026555
KAT5 POLI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
REV3L MAD2L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22828282 8385420
MFHAS1 POLI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
TRIM39 POLI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
YWHAG POLI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCA POLI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POLI RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 POLI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10023689 10913176
SP1 POLI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22509890 21787586
REV1 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 REV3L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
UBA52 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBC RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 TBPL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS27A USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
USP7 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 26235645
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBE2V1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1551980 11057907
TRIM25 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
USF1 TRIM25 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9714786 9245730
UBA52 USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
USP7 UBA52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 26235645
UBC YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
TRIM23 UBA52 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ERCC6 POLI â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
TRIM25 UBB â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ERCC6 RPS27A â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ERCC6 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
RPS27A TRIM23 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
TRIM23 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
PCNA UBA52 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
RNF11 UBC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15231748 20676133
REV1 RPS27A â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
UBB UBE2L6 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
UBC UBE2L6 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
POLI UBA52 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
TRAF6 USP7 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
UBA52 UBE2L6 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
NEDD8 UBB â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
REV1 UBB â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RPS27A TRIM25 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TRIM25 UBC â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
POLI UBB â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
ERCC6 UBC â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
TRIM23 UBC â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
POLH UBC â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
PCNA UBC â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
POU2F1 SP1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
ISG15 UBA7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
POLI RPS27A â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
UBA7 ISG15 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17597759 32296183 14976209 16189514 18356159 16009940 16884686 22693631 25416956 20975683
UBC POLH â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17304240 16763556
UBB RNF11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 14755250 33961781
UBA52 USP7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CALCOCO2 UBC â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
SP1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10651903 34252870 16478997 11030335 11517158 15647279 17623675 17906698 28425985 32115405 31536933 12200149 24530506 23714681 10362258 22415975 16734381 19062177 10899165
TBP TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
REV1 UBC â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PCNA UBB â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
TRAF6 UBE2V1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RPS27A UBE2L6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
NEDD8 UBA52 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
POLI PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15342632 11724965 33166398 34165573 23248005 16763556 18931444 26903512
REV3L PCNA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
XRCC1 PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30260704 20227374 16713569 34111398 15107487
PCNA MAD2L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
UBA52 DAZAP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
JDP2 POLI â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10339547 11250901 16358415
RPA1 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 MAD2L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
RPA2 MAD2L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
REV1 MAD2L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
RPA3 MAD2L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
MAD2L2 POLI â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
REV3L POLI â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
REV3L REV1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
REV1 REV3L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15189446 18953031
TP53 REV3L â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
REV3L RPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
REV3L RPA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
REV3L RPA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
UBA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17597759 24816145 21209336
UBE2L6 UBE2N â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16112642 16428300 16122702
RPA2 RPA3 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
UBE2N UBA1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 27173435 14517261 29537486 18678647 30097011 27182664 25527291 33619271 31638574
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
UBA1 UBE2N â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
RPA3 RPA2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24126761
UBA1 UBB â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
POLI REV1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
RPS27A TRAF6 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
NEDD8 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
POLH REV3L â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
NEDD8 RPS27A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
PCNA RPS27A â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
UBB USP7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
RPS27A USP7 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TRIM25 UBE2N â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
UBA1 UBA52 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
UBB UBE2N â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBE2N â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
RPS27A UBE2N â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
POLI UBC â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
RPS27A UBA1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
POLH PCNA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 23761444 21855803 23388460 28831681 22989887 20129057 23042605 26988343 21791603 23345618 11585903 27770570 20159558 16763556 15149598 16189514 30963698 15342632 31796584 24474685 25766642 30563767
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
RPA1 TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RPA1 RPA3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPS27A TP53 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
MAD2L2 REV3L â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
UBA1 UBC â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
MAD2L2 REV1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
POLH REV1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PCNA RPA1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
TRAF6 UBE2N â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
REV1 REV3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPA1 RPA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UBC UBE2N â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF1 TBP â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RPA2 PCNA â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA POLI â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11756412 12466554 14624239 14726013 15189446 15703371 16697054 17035102 17652783 18196958 18931676 19258535 19622404 19686080 1974050 19847258 22021614 23065650 23414611
PCNA REV1 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15189466 15703371 16337601 16337602 16697054 17035102 17517887 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 20227374 22021614 22266823 22562137 23065650 23414611
PCNA POLH â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15703371 16337601 16337602 16697054 17035102 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 22021614 22266823 22562137 23065650 23414611
PCNA XRCC1 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 PCNA â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA POLI â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11756412 12466554 14624239 14726013 15189446 15703371 16697054 17035102 17652783 18196958 18931676 19258535 19622404 19686080 1974050 19847258 22021614 23065650 23414611
PCNA POLH â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15703371 16337601 16337602 16697054 17035102 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 22021614 22266823 22562137 23065650 23414611
PCNA XRCC1 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
UBE2N PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10880451 16224103 16518696 17652783 18157158 18196958 18525240 18647995 19217833 19258535 19851286 20675655
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
UBE2N PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 18772547 12820959 18525240 19459846 19258535 19440234 17652783 15147722 10880451 15169778 19851286 10722742 18647995 18006823 18157158 16224103 20675655 16518696 18196958 15340381 10721693
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
PCNA POLH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20129057 20159558 24474685 16357261 16189514 19208623 30963698 15342632 21855803 15149598 23042605 21791603 23761444 23345618 16763556 11585903 23388460 25766642 26988343 27770570
PCNA POLI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16763556 26903512 15342632 23248005 11724965 19208623 16357261 18931444
PRKCA DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12958364 11940581 21386996 11313945 15567848
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
ERCC6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16713569 10882116 19221478 18784753
UBE2L6 ISG15 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11157743 15485925 18583345 15131269
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
REV1 POLH â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10884424 11756412 12466554 14624239 14657033 14726013 15189446 15688063 15703371 16337601 16337602 16611994 16697054 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 1974050 19847258 20129063 20675655 22021614 22266823 22562137 23065650 23414611
REV1 POLH â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10884424 11756412 12466554 14624239 14657033 14726013 15189446 15688063 15703371 16337601 16337602 16611994 16697054 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 1974050 19847258 20129063 20675655 22021614 22266823 22562137 23065650 23414611
POLH REV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22828282 19170759 15189446 34725419 24409475 22691049 19157994 16824193 21690293 15380106
REV1 POLI â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11756412 12466554 14624239 14726013 15189446 15703371 16697054 17035102 17652783 18196958 18931676 19258535 19622404 19686080 1974050 19847258 22021614 23065650 23414611
REV1 POLI â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11756412 12466554 14624239 14726013 15189446 15703371 16697054 17035102 17652783 18196958 18931676 19258535 19622404 19686080 1974050 19847258 22021614 23065650 23414611
TBP POLI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9837969 8887672 23454483 9811537 8058785 19767748
UBTF POLI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21177859 1502143 9203586 10339547 21151873 16858408 16971462
PRKCA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18812399 9935181 15659650 9315650 19933256 16713569 9571186 1454855
RPA2 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 XRCC1 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 RPA3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 XRCC1 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
SP1 UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19733223 17409431 11872750
TBP TAF1 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 7597030 17375202 7680771 9153318 9660973 17884155 18391197 16713569 15870300 29111974 15564746 8858156 31753913 8995708 9858607 9674425 17967894 19240132 9603525 9311784
TAF1 TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16858867 11316804 9699517 15808844
TAF1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 28673515 15053879 20124405 16713569 29556568 24289924
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
TP53 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18172499 18695251 24667498 22056774 17290220 17592138 12421820 18413597 20173098 19556538 21857681 17470788 18359851 19805293 19196987 12640129
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
UBE2N TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18710948 1551980 17327397 11057907 15147900 18981220 21113135 17709375 31074699 19549727 18617513 24610907 27791197 29432170 19465916 23885119 15327770 27173435 21872579 25548215
UBE2L6 UBA7 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11157743 15485925 18583345 15131269
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368