Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TRAF1 NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
BRME1 TRIM23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LMO2 BRME1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CYTH1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 EAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
MKRN3 ENKD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UBQLN1 FAM83A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRIM29 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GEM TRIM23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HSP90AA1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBE2I IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14651848 16906147
TBK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNFAIP3 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11389905 5214127
SLC25A6 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SQSTM1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16874300
IQUB TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
JOSD1 TRIM27 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UBE2I KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KAT5 SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 POLI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL42 UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 LGALS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TRIM29 MLH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 MLH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15781865
TP53 POLI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10023689 10913176
TRIM27 PPP1R18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PSMA1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RNF126 UBE2D4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RNF126 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SNW1 TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
SNW1 UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZBTB16 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24821728 24821727
ZBTB16 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TRAF1 ZBTB16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
ZNF581 TRIM23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRIM23 TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
ZNF417 TRIM27 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
ZBTB16 TRIM27 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRIM27 ZBTB16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TRIM29 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBQLN1 TRIM32 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ZNF20 TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
ZNF581 TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
UBE2N UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
FAM90A1 ZNF581 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
SNW1 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31076518 20467437
TRAF1 TBK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25996949 28514442 33961781
PIAS2 TP53 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
MKRN3 PSMB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
RAD18 BAG1 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
TP53 UBE2D1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
RAD18 TRIM27 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
ARF6 CYTH2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
KAT5 CBX8 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16169070 22094252
SIAH1 UBE2D1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CWF19L2 SNRPB2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
TRAF6 TRAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27107012 32296183 25416956 21988832 21516116 28514442
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
USP20 ZNF408 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CCDC13 CDR2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
GEM TRIM32 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
FAM110A MKRN3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
IKBKG TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MKRN3 RTP5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CYTH2 ARF6 â—¼   GTPASE_REACTION ✅ + 0.88 0.88 Signor 14565977
IKBKG TNFAIP3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
GPANK1 KRT75 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
FAM90A1 NUDT21 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
GEM MKRN3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
MRPL4 MRPL45 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
TRAIP TRAF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17544371 9104814 16713569
KRT75 KRT76 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CDR2 FAM90A1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
TNFAIP3 TRAF6 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
TNFAIP3 UBE2D1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CYTH1 ARF6 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10652308 11050434 1511013
SNAI1 RIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19837165 18089779 18160707
SIAH1 BAG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9582267 16189514 16713569 12421809
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18431400 15781865
UBE2N RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
TNFAIP3 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18353649 15661910
KRT75 NUDT21 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CDR2 GEM â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
TRAF1 TRAF6 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 8153045 21516116
CDR2 LENG1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CWF19L2 SNW1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
SQSTM1 TRAF6 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
IKBKG TRAF6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
SNRPB2 SNW1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
PRPF31 SNRPB2 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
PIAS2 UBE2I â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
TRAF6 UBE2N â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMA1 PSMB1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CYTH2 ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9417041 16189514 14565977
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TRAF6 IKBKG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18180283 18347055 21220427 16547522
TRAF1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
TRAF1 IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
TRAF6 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17562858 17728323 17947236 14695475 18180283 15620648 15125833 12867425 11057907
TNFAIP3 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 21988832 11389905 22099304 23032186 20932475 26802121 31585000 10755617
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
TP53 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20181957 20421190 14985507 11852084
TP53 SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12077306 12438652 14985507 15326481
SNAI1 SNAI2 â—¼   UP_REGULATES ✅ + 66.0 1.0 ACSN 10048576 11283614 11708773 12490555 12545156 12668723 14623871 14673164 15111329 15151915 15155580 15181457 15448698 15459715 16001073 16079281 16232121 16510505 16556862 16617148 16716598 16831886 17018611 17055429 17093497 17403902 17490644 17537911 17550342 17563753 17615296 17671186 18172008 18297062 18832382 19208835 19412634 19564415 19597490 19935649 20027199 20702634 20706219 20713526 20731704 21041997 21051859 21159887 21199805 21317430 21577210 21685935 21883379 2191300 22006115 22286765 22406545 22439866 22514743 22796940 22945800 23140366 23869868 8844971 9157999 9618481
TRAF6 SQSTM1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11274345 12620219 14660645 15125833 15340068 15721744 16252010 17948050 18264787 18758450 18922473 19161412 20531300 21981924 25002027 26587781 28574505
TRAF6 SQSTM1 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11274345 12620219 14660645 15125833 15340068 15721744 16252010 17948050 18264787 18758450 18922473 19161412 20531300 21981924 25002027 26587781 28574505
TBK1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 24818040 25040165 29147513 28655770 31810986 28871090 25505069 32966780 27846364 31444413 27404485 34996837 32835772 24886973 30223576 29930914 29973599 27005665 22921120 25723488 25972374 33084718
SQSTM1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15870274 27458013 10747026 27681126 16079148 16189514 18382763 16874300 11244088 17389358
TNFAIP3 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 17703191 18164316 20622874 15334086 23018911 9928991 23737552 23105109 31625129 11463333 21220427 18239685
UBE2D1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
UBE2N TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18710948 1551980 17327397 11057907 15147900 18981220 21113135 17709375 31074699 19549727 18617513 24610907 27791197 29432170 19465916 23885119 15327770 27173435 21872579 25548215
RAD18 UBE2N â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
RAD18 ZNF581 â—¼   KO_DOWN_REGULATES ✅ - -1.62 1.61 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368