PLEC
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ATR
|
PLK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12147700
|
ATR
|
HERC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20023648
|
ERAP1
|
USP20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
UBC
|
SNAI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7718905
20385133
|
HIF1A
|
SNAI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23979441
23496980
|
CTNNB1
|
SOX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17218525
17875931
|
SOX4
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17875931
24970928
|
MAP1LC3A
|
SQSTM1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
PSMD11
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PSMD6
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PSMD12
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PSMD7
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TRAF6
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0906941106
19955404
|
MEOX2
|
MDFI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
ZNF408
|
MDFI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
FATE1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
SPRY2
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
VHL
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218395
16511565
|
PRKCZ
|
VHL
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5219754
17350623
|
CTNNB1
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16983094
0606850103
|
ADRB2
|
ARRB2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
ADRB2
|
VAPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
ADRB2
|
USP33
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7291579
19424180
|
CCP110
|
NEURL4
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8392017
22441691
|
SAMD12
|
USP20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.8
|
0.8
|
HuRI
|
32296183
|
UBC
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
5216530
12857745
|
APBA2
|
HERC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
HERC2
|
ECI2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22261722
29426014
|
HERC2
|
EIF3E
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25476789
29426014
30279242
|
HERC2
|
EIF3C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25476789
29426014
30279242
|
ARRB2
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19955404
16378096
25425640
|
TRAF6
|
UBC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
14743216
17703191
19820695
18239685
|
ARRB2
|
USP33
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ASCL1
|
USP20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
ATR
|
RAD17
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
11687627
|
TRIM23
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
TRAF6
|
ULK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
33201521
23524951
|
TRAF6
|
PSMD6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17353931
14743216
|
ADRB2
|
VAPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24561123
28298427
|
BHLHB9
|
USP20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
FATE1
|
USP20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
PSMD11
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
PSMD12
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
PSMD7
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
TRAF6
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
8153045
21516116
|
USP20
|
ZNF408
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
MAP1LC3A
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
GPRASP2
|
USP20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
TRAF2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
MEOX2
|
USP20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
VAPA
|
VAPB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
HERC2
|
NEURL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
TRAF2
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
32296183
16189514
16260598
21782231
16713569
25416956
9500555
33961781
21516116
21903422
|
ATR
|
RAD17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20424596
10608806
11418864
14724280
|
AURKA
|
PLK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22939629
18615013
18773538
|
ADRB2
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
MDFI
|
USP20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
HIF1A
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
MAPK6
|
PLK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RAD17
|
RFC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
14624239
33961781
14605214
|
RAD17
|
RFC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
14624239
33961781
14605214
|
RIPK1
|
TRAF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25416956
24735611
23972990
16603398
8612133
32296183
16291755
11181075
19815541
24434549
30561431
21810480
11479302
31502302
27768232
20577214
25716317
21282461
25882049
8702708
9020361
16713569
29352166
23007157
|
EIF3C
|
MAPK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ADRB2
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23208550
24658140
17148612
24561123
27226565
|
VAPA
|
VAPB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
19515777
16227268
9920726
26496610
33961781
26186194
34079125
|
MAPK6
|
APBA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MDFI
|
ZNF408
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
PRKCZ
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
TRAF2
|
RIPK1
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
10795740
|
TRAF2
|
RIPK1
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
18621737
|
TRAF6
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
SQSTM1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
RIPK1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
SQSTM1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
MAP1LC3A
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
RFC2
|
RFC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
22939629
9488738
26344197
24981860
|
SQSTM1
|
MAP1LC3A
|
â—¼ COLOCALIZATION
|
✅
|
|
0.95
|
0.95
|
mint
|
19427866
7034152
|
EIF3C
|
EIF3E
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
18599441
17403899
10504338
22863883
33961781
24981860
23623729
22939629
26344197
|
RAD17
|
RFC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
RAD17
|
RFC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
RFC4
|
RAD17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
16189514
14624239
11907025
33961781
14605214
12400013
|
HIF1A
|
VHL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15082527
11865071
11226425
10944113
14556007
11986208
15527772
17973296
12538644
26735336
24899725
12606543
21358672
24015760
16611863
23401859
18062927
21332579
15805242
19940151
12086861
27281823
23413029
33060856
11292862
24316222
16155211
24857547
22932900
29121446
11292861
12101228
15060148
18047470
16278378
21602890
27320910
12464182
26611735
32589900
18402654
25500545
12050673
18694926
26215701
10878807
25361009
11641274
22351759
34007068
18305400
21316481
11024059
34195792
26037477
34174286
33039559
10823831
26743088
31810986
10353251
15833858
17558023
11566883
23580587
27563096
18985005
19123984
25438054
12682018
18323857
23387829
17442832
33550096
18222538
18426857
17047048
12004076
34230460
23318261
33961781
12808024
21335603
12586829
17353276
11358837
28514442
20724477
16140212
12205091
20049704
16862177
11331613
32535973
15721254
14691445
15385570
10973499
15611064
17981124
28775317
12925778
26496610
17339318
30237125
20458141
20639890
17986458
19147576
28425505
11504942
22369643
18264140
16511565
12351678
14600153
30988076
17132228
|
UBC
|
USP21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
RFC2
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
9228079
9751713
28514442
9488738
22939629
8692848
15655353
33961781
24981860
16582606
9092549
26344197
|
RFC3
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
32296183
9488738
22939629
8692848
33961781
9092549
26344197
|
RAD17
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMD6
|
PSMD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
EIF3C
|
EIF3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
RFC2
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
UBC
|
UCHL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RFC3
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ATR
|
RAD17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
38.0
|
1.0
|
ACSN
|
10884395
11877377
12086603
12766152
14726013
14988723
15136767
15175241
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17493829
17582221
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19847258
20051983
20478261
8943031
9524127
|
ATR
|
CLSPN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
61.0
|
1.0
|
ACSN
|
10884395
11756412
11877377
12086603
12466554
12766152
12875843
14614141
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15242590
15375219
15377654
15459660
15485915
15703371
15743907
15798197
16530042
16697054
16713580
16805667
16818604
16880517
16885023
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
17855402
18157158
18451105
18469862
18543256
18677104
18931676
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
19686080
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
CLSPN
|
â—¼ SHARES_COMPLEX
|
|
|
61.0
|
1.0
|
ACSN
|
10884395
11756412
11877377
12086603
12466554
12766152
12875843
14614141
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15242590
15375219
15377654
15459660
15485915
15703371
15743907
15798197
16530042
16697054
16713580
16805667
16818604
16880517
16885023
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
17855402
18157158
18451105
18469862
18543256
18677104
18931676
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
19686080
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
RAD17
|
â—¼ SHARES_COMPLEX
|
|
|
38.0
|
1.0
|
ACSN
|
10884395
11877377
12086603
12766152
14726013
14988723
15136767
15175241
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17493829
17582221
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19847258
20051983
20478261
8943031
9524127
|
ATR
|
RAD17
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
38.0
|
1.0
|
ACSN
|
10884395
11877377
12086603
12766152
14726013
14988723
15136767
15175241
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17493829
17582221
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19847258
20051983
20478261
8943031
9524127
|
ATR
|
CLSPN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
61.0
|
1.0
|
ACSN
|
10884395
11756412
11877377
12086603
12466554
12766152
12875843
14614141
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15242590
15375219
15377654
15459660
15485915
15703371
15743907
15798197
16530042
16697054
16713580
16805667
16818604
16880517
16885023
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
17855402
18157158
18451105
18469862
18543256
18677104
18931676
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
19686080
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
RAD17
|
â—¼ UP_REGULATES
|
✅
|
|
38.0
|
1.0
|
ACSN
|
10884395
11877377
12086603
12766152
14726013
14988723
15136767
15175241
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17493829
17582221
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19847258
20051983
20478261
8943031
9524127
|
ATR
|
CLSPN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18309293
24500207
19473886
12766152
18077418
|
ATR
|
RAD17
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
11418864
26854234
19230642
14500819
25893301
16872911
21680713
16885023
33820915
24971543
10608806
11687627
|
AURKA
|
PLK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
18566290
23618492
27721411
24338364
15713655
28126323
34260926
19364923
33805672
33771996
32284347
27504491
33898950
10980711
26206521
21474997
32060423
27662907
28994651
33963314
18615013
23695676
34197606
18669648
25925375
26114094
19228686
28591578
22281053
18691976
20603326
15611664
27068477
27908669
26919439
26012549
18477460
34140642
25660017
27899378
19369195
21454580
25871386
24349352
12207013
20869364
11854496
20633640
28351953
24667170
25042804
|
PLK1
|
CLSPN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
16885022
16934469
15163406
16885021
|
CLSPN
|
RAD17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
38.0
|
1.0
|
ACSN
|
10884395
11877377
12086603
12766152
14726013
14988723
15136767
15175241
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17493829
17582221
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19847258
20051983
20478261
8943031
9524127
|
CLSPN
|
RAD17
|
â—¼ SHARES_COMPLEX
|
|
|
38.0
|
1.0
|
ACSN
|
10884395
11877377
12086603
12766152
14726013
14988723
15136767
15175241
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17493829
17582221
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19847258
20051983
20478261
8943031
9524127
|
CLSPN
|
RAD17
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
38.0
|
1.0
|
ACSN
|
10884395
11877377
12086603
12766152
14726013
14988723
15136767
15175241
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17493829
17582221
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19847258
20051983
20478261
8943031
9524127
|
CLSPN
|
RAD17
|
â—¼ UP_REGULATES
|
✅
|
|
38.0
|
1.0
|
ACSN
|
10884395
11877377
12086603
12766152
14726013
14988723
15136767
15175241
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17102137
17116885
17296725
17303408
17384638
17493829
17582221
18469862
18677104
18995830
19282663
19342888
19622404
19793801
19847258
20051983
20478261
8943031
9524127
|
TRAF6
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11274345
12620219
14660645
15125833
15340068
15721744
16252010
17948050
18264787
18758450
18922473
19161412
20531300
21981924
25002027
26587781
28574505
|
TRAF6
|
SQSTM1
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11274345
12620219
14660645
15125833
15340068
15721744
16252010
17948050
18264787
18758450
18922473
19161412
20531300
21981924
25002027
26587781
28574505
|
SQSTM1
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
12702723
15340068
16252010
16498403
20531300
21981924
23069999
25002027
26587781
28574505
9184224
|
MAP1LC3A
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
20061800
23022382
23459205
35044719
22963397
36036324
31053714
21045561
25921531
19250911
17580304
21628531
20204693
28740232
23640897
25686248
24100292
26075355
20562859
22658522
25984893
21460636
16286508
19427866
32296183
23989536
19021777
26268733
22714671
24998849
18653543
31366950
33436498
16169070
23239879
26754771
|
SQSTM1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
15870274
27458013
10747026
27681126
16079148
16189514
18382763
16874300
11244088
17389358
|
SQSTM1
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26416459
10356400
19850933
|
TRAF2
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
92.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11668179
11875494
12048245
12215447
12556535
12646658
12655147
12702723
12724420
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17496911
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21614932
21826665
22427918
22955274
23010170
23069999
23070005
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
28765050
8910423
8974401
9379049
9488730
9582321
9759866
|
TRAF2
|
RIPK1
|
â—¼ SHARES_COMPLEX
|
|
|
92.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11668179
11875494
12048245
12215447
12556535
12646658
12655147
12702723
12724420
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17496911
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21614932
21826665
22427918
22955274
23010170
23069999
23070005
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
28765050
8910423
8974401
9379049
9488730
9582321
9759866
|
TRAF2
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
92.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11668179
11875494
12048245
12215447
12556535
12646658
12655147
12702723
12724420
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17496911
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21614932
21826665
22427918
22955274
23010170
23069999
23070005
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
28765050
8910423
8974401
9379049
9488730
9582321
9759866
|
TRAF2
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
8702708
8612133
25416956
16713569
18621737
25882049
16291755
18981220
21741934
21232017
20577214
11181075
10795740
23972990
21119000
15175328
20203691
21810480
21282461
9712898
32296183
23007157
25716317
20448643
12887920
24735611
15258597
24434549
19815541
16603398
11479302
9020361
|
HIF1A
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
VHL
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
HIF1A
|
FECH
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
HIF1A
|
VHL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12205091
15930297
21887475
22150821
22396654
15962286
23159849
17482131
17140440
16883594
|
HIF1A
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18562694
19828020
|
VHL
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
123.0
|
1.0
|
Omnipath
|
17145710
21332579
24857547
12682018
26496610
11292861
11024059
15060148
16278378
12586829
17353276
12004076
12205091
17339318
10823831
11226425
21602890
16862177
15611064
12351678
16140212
11865071
26037477
16611863
10973499
23401859
25361009
11331613
18305400
25438054
14691445
17047048
12538644
22932900
18985005
26735336
21358672
18323857
10878807
19147576
16511565
17973296
23413029
24316222
11986208
12808024
12464182
23318261
22369643
19940151
15721254
20724477
21335603
16391536
23387829
18694926
26743088
14556007
18264140
10353251
15082527
11358837
11292862
11566883
12050673
19123984
17558023
27281823
15805242
11641274
25500545
34174286
24899725
12606543
32535973
17132228
24015760
12086861
11504942
35589690
26215701
22351759
12925778
18222538
17986458
14600153
10944113
23580587
26611735
18426857
20049704
|
PRKACA
|
AURKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
23861900
16222244
16246726
33744274
29764989
26165940
11039908
17545617
27242098
26481147
28869606
26134678
33988677
26831064
33760847
16083426
17895985
|
PRKACA
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
33914026
16199882
22173096
21303971
33815677
22094462
17287208
26068882
26884171
33605402
21506126
24117889
12297048
21822311
16476742
|
PRKACA
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9461522
24003153
10753752
11146000
2987243
27481942
27646272
|
ARRB2
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
23208550
17148612
17666399
24658140
27226565
2163110
24561123
22364396
|