Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UBB UBBP4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TPT1 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1106300109 22451927
UCHL3 ATXN7L3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
UBC COPS5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7229502 19214193
UBC OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11689694 5214752
SPRED1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UCHL3 RPS27A â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
UCHL3 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 26235645
UCHL3 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21453705 8149649
SPRED1 UCHL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
XRCC5 TPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1106300109 22451927
UCHL3 TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
UCHL3 UBA52 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
UCHL3 UBA52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 26235645
UBA6 UBC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBA6 UCHL3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
OTUB1 FOXM1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 27167337 31879190 26148240
NEDD8 OTUB1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24654937 18954305 33665565
UBQL1 UCHL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33277362 22939629
ENOA UCHL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30559450 26344197
UBP48 UCHL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33903120 22939629
UCHL3 THIM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30559450 26344197
RPS27A UBE2S â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
UBA6 UBP48 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33903120 22939629 26344197
UBP48 UBB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33903120
SOX2 XRCC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 21280222 23667531
UCHL3 ZMYM6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPT1 UBA52 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
UBQL1 UBC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20059542 19798103
UBBP4 UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
UBA52 UBE2S â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
NEDD8 UBB â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RPS27A UBQLN1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RPS27A UBA6 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
NEDD8 AHR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12215427
CSN5 UCHL3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19615732 28583475
UCHL3 CLPB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 28514442 26186194 33961781
CSN5 NEDD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 25144743 19615732 21145461 16503656
NEDD8 UBA52 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
RPS27A TPT1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
POGK UCHL3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NEDD8 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NEDD8 RPS27A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
UBB UBE2S â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
UBA52 UCHL3 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
OTUB1 UBC â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
UBB UCHL3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
UBC UBQLN1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
UBA52 UBBP4 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBBP4 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UCHL3 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
UBC UBE2S â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBC UCHL3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
XRCC5 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
AURKB ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22099307 27493659
ATM TDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26421495 29216365 24947324 29078113 19851285 34181949 24493735 29718323
ATM SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22588298 23277204
ATM PPP1R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18250156
FOXM1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15817462 15689977 17173139 16314512
ZEB1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 17997862 16424029 17615296 23890107 23160379 19435871 18411277 23667256 20139075 12508111 12714599 23518002 20207041 16862183 22249256 18321996 18805502 19706487 19839049 22147512 23743934 15674322 19921427 16804902 20332115 10949939 21771732 18487993 17655524 15311212 12161443 21593765
ZEB1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 15169839 9389648 17615296 22796940 19839049 20818389 21224848 20519943 21685935 12508111 11309385 11074002 225147423 19597490 12743038 14673164
ZEB1 SOX2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368