Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RBX1 DTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17588513 19481520
ELOC CUL2 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 5219492 17183367
CUL2 ELOC â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 19327355 7014028
HIF1A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15794924 19828020
JUN JUND â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8922393 2504580
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
SKP1 FBXL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SKP2 SKP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CUL3 BTBD2 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 34591642
UCHL1 NEDD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NEDD8 UCHL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
NCOA1 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14966289 15988012
CDK2 P53 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25241761 12064478 10747897 19556892 10348343 10884347
CUL4A UBC12 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32494016 28581483 21987584
CDN1B CUL1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18805092 34237211 11961546 22959436 10559916
UBC12 CUL3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21247897 28581483 26286618 28475037
CSN5 NCOA1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16713569 10722692 15604093
CSN5 CDK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 23926101
CDK2 UCHL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21319273 23543736
CUL4B UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 34026424
CUL4B TOIP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31973889
SKP2 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 21119685
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
CUL5 DCA11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31253590 21145461
CSN5 DDA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 19295130
DDA1 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19295130 26496610
CUL1 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22474075
CSN8 DTL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN8 FEM1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN5 FEM1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN7B FEM1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VHL MIF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 21942715
FBXL5 RBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24157836 19762597
CSN7A RBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19295130 26496610
RBX1 ELOC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33504946 12149480
RBX1 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30349055 12481031
RBX1 FBX22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12481031 33504946
CSN5 STRAP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CUL4A HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 12481031
CUL4A NFKB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 30945288
CUL4A SKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22474075
CUL2 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 33961781
CUL2 MYOV2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 33961781
CUL2 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 19295130
CUL2 UBC12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 28581483
DET1 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IKKB CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23636414 19656241
FXL14 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBXL5 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBX7 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NEDD8 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
KLH10 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN5 EIF3F â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 31950832
CSN5 NCBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
SKP2 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NEDD8 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
APBB3 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FXL14 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBXL5 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CRBN CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
DET1 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
JUN GBLP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25609649 21860413
JUN P53 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31182485 25609649
SKP2 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 6540196 18239684
CUL1 MYOV2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 23776465
CUL1 HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34333526 21145461
CUL1 CARM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 34480022
CSN6 SKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 19295130
P53 SKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22653443 23443559
KLH10 CUL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CUL3 MYOV2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 23776465
CUL3 TERA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22466964
SKP2 LRCH2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SKP2 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NEDD8 DCA11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18247557
NEDD8 GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 24654937
NEDD8 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
NEDD8 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
NEDD8 PYRG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 24654937
CSN5 HIF1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11707426 26352431 15082527
NFKB1 GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 25609649
NFKB1 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 25609649
NFKB1 HSP76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 25609649
CAND1 HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28611215 21145461
VHL HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23976881 21942715
VHL CSN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15082527 12032852
CSN5 AIMP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 CARM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
DENR CSN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR CSN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR BTBD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TP4AP NCOA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CRBN CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
CRBN CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
CSN5 GYS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN8 BTBD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN7A BTBD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
CSN5 DNM1L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
ERN1 UBP14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24951540 19135427
CSN7A DCAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
CSN8 DCAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCAF4 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCAF4 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCAF4 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBXL5 CSN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FA98A BTBD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN7B BTBD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN8 BTBD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BTBD1 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 CSN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN5 DNJC9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 FBX46 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CSN5 FXL14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 33961781
CSN5 HS71L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CSN5 PIMT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 ELOB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31253590 21145461
CSN5 FA98A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 YTDC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 CALD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 METK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 PLAK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 RLA0 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 HSP77 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CSN5 LRCH2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CSN5 RTCB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 DCD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 ELOC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 PABP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 GTPB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 TP4AP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CSN5 UBP14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18624398 31950832
CSN5 CTNA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 HSP76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CSN5 REQU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 28533407
CSN5 GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CSN5 HNRPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28611215 21145461
CSN5 PYRG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 RT27 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
CSN5 RHBT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31871319
CSN5 CENPW â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29863914 23926101
MARE1 CTNA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29162697 26496610
GRP78 HS71L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 22939629
TERA A4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 28315680
APBB3 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBX7 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LRC14 ELOC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 19295130
LLR1 ELOC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19295130 15601820
FXL14 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LLR1 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19295130 26496610
APBB3 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBX7 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBX7 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBX7 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCA11 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH13 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 33961781
FXL14 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 CSN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH13 CSN8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 33961781
MYOV2 CSN8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26456823
APBB3 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 RHBT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN7B PIMT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH22 ALR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDK2 FBRL â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17353931
CUL4B CSN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22038470 31973889 16861906 26496610 33961781 21145461 34026424
CUL4B MYOV2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 33961781 31973889
CUL5 CSN7B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31253590 21145461 33961781
TP4AP DDA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 20551172
DDA1 DDB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20562859 33961781 26496610
DDA1 DCA11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20562859 31155351 33961781 19295130
DDB1 NEDD8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16503656 18274552 16964240 21145461 18247557
DDB2 CSN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16260596 12732143 33961781 26186194 19295130
DDB2 CSN8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16260596 26496610 12732143 33961781 26186194
DDB2 CSN7B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DDB2 CSN3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16260596 26496610 12732143 33961781 19295130
DDB2 CSN7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16260596 26496610 12732143 33961781 26186194
DDB2 CSN4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16260596 26496610 12732143 33961781 26186194 19295130
CSN5 DTL â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31950832 23555860 16861906 21145461 19295130
ERCC8 CSN8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12732143 29531219 16751180
CSN3 FEM1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CSN2 FEM1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FEM1B ELOC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18187417 15601820 19855191
FEM1B RBX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 15601820 33504946
FEM1B ELOB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18187417 31253590 15601820
P53 RBX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22653443 30349055 23443559
LLR1 RBX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19295130 15601820 33504946
CSN5 RBX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19295130 30349055 18850735
RBX1 ELOB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12048197 33504946 31253590 12149480
JUN TOP2A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8387155 25609649
CUL4A TOIP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 31973889 16964240
CUL4A CSN4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17079684 31973889 18606781 16964240 21145461 19295130
CUL4A MYOV2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 33961781 31973889
LLR1 CSN3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
CSN3 BTBD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
CSN3 BTBD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
CSN3 CRBN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24292625 19295130 27029275
CSN3 DCA11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
CSN3 DCAF4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DCA11 CSN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
FBX17 CSN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
LLR1 CSN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
UBC12 CSN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN2 DCAF4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CSN2 BTBD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CSN2 BTBD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CSN2 FBX7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SMAD4 JUN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10220381 25609649
JUN JUND â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25609649
CUL3 CSN8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 33961781 26286618
VPRBP NEDD8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17609381 21145461 33355139
NEDD8 ELOC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16503656 21145461 18247557
NEDD8 ELOB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16503656 31253590 21145461 18247557
CSN4 CRBN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24292625 19295130 27029275
ERN1 CSN5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17951406 15234121
CSN5 ASB6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 33961781 31950832
CSN4 BTBD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 33961781
UBC12 BTBD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN7A BTBD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
FBRL CSN5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12082530 21145461
GBB5 CSN5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
UBC12 CSN5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN5 KLDC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 18850735 31950832
CSN5 TPD54 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CSN5 FNIP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
UCHL1 P53 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18666234 20395212 32814053 29126443
P53 GRP78 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17184779 31152661 32807901 23443559
GRP78 HSP71 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22863883 22939629 26496610
A4 UCHL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32814053 16049941 25466238
TP4AP IKKB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32889079 14585990
UBC12 CSN4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN4 DCA11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 33961781
CSN4 FBX17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
LLR1 ELOB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31253590 19295130 15601820
CSN6 ELOB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31253590 21145461 19295130
LRC14 ELOB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31253590 21145461 19295130
RHBT1 CSN7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31871319 33961781
UBC12 CSN7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN7A DCA11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26496610 33961781
VPRBP CSN7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18606781 19295130 26496610
FBX17 CSN7B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
UBC12 CSN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
LLR1 CSN8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 33961781
VPRBP CSN8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17609381 33355139 33961781 28514442
UBC12 KLH18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
UBC12 RHBT1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
UBC12 CSN7B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
UBC12 KLDC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN7B DCA11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 27173435
KLHL9 KLH22 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 19995937
PIMT KLH24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PIMT KLH18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PIMT KLDC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CSN8 CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 21145461 30587576 11337588
CSN4 CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 21145461 11337588
CSN1 CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 21145461 11337588
CSN3 CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 21145461 19295130 11337588
CSN5 CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 30587576 31950832 21145461 11337588
CSN7A CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 21145461 33961781 11337588
CRBN RBX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24292625 30042095 23983124 27029275 26990986 33961781 20223979
TOP2A CSN5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21254166 15126503
CUL4A CDN1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19056892 16467204 16537899 26613412
CSN1 CUL2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21145461 33961781 11337588
1433Z EIF3F â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15161933 17361185
CSN2 JUN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16045761 25609649 10903862
SMAD4 SKP2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16865698 15314162
CSN6 JUN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25609649 26237449 10903862
CUL3 BTBD1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 34591642
CUL3 METK2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21145461 27213918
REQU NFKB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20460684 22334708
NFKB1 HS71L â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14743216 25241761 25609649
BTBD1 BTBD2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 12878161 33961781
1433Z RLA0 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15161933 17361185
PP1G P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17274640
CSN4 P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22653443 11285227 24725084
P53 HS71L â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17184779 31152661 25241761 23443559
FBRL RENT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
PABP4 FBRL â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29568061 26344197
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
DET1 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 16949367 31973889
CUL4A DDA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31973889 17452440 16964240 21145461 19295130 16949367
DCA11 DDB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17079684 28514442 28446751 27203182 32235678 28453520 33783207 33961781 31155351 16964240 19295130 19109893 16949367
CSN3 DDB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16036220 22767593 10777491 33961781 16964240 19295130 16949367
DDB1 CSN6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22767593 16964240 21145461 19295130 16949367
VPRBP CUL4A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17079684 17630831 20870715 18606781 30590706 31973889 17609381 25532805 21145461 19295130 30166453 33355139 16949367
HIF1A JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25879517 19738058 11739718
CAND1 SKP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29499133 21145461 12504026
NCOA1 NFKB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9556555 10847592
GYS1 PP1G â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 26186194 28330616
CSN5 A4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23926111 21832049 31413325
CSN5 MYOV2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21145461 23776465 26456823 33961781
P53 IKKB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19883646 19196987
MYOV2 CSN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 26456823 32034103
NEDD8 VHL â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CUL4A DCAF4 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CUL4B DDA1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CDK2 UBC12 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 28581483
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
CUL4B GRP78 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
CSN2 CUL5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31253590 21145461 32047038 11337588
DDB1 CSN5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22767593 18850735 23357576 16964240 21145461 19295130 16949367
CUL2 PLAK â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 22863883
RENT1 NCBP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23665581 19417104
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
ELOC CUL3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 21988832
CSN5 JUND â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 16713569 8837781
CSN5 NFKB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 21988832
CSN5 CAND1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 16861300
P53 BTBD2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 16169070
GBLP CSN5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 18624398
1433Z CSN5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 20936779
CSN5 UCHL3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19615732 28583475
CSN5 FBX22 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 19615732
CSN5 TOIP2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 19615732
P53 FBX11 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32807901 17098746
CUL4A DDA1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CUL1 CDK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 9636170 26186194 21145461 23455922
CUL4B CSN7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31973889 26496610 33961781 21145461 19295130
CUL4B CSN7B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31973889 33961781 24981860 21145461
CUL4B CSN8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31973889 26496610 33961781 27173435 24981860 21145461
ASB6 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31253590 33961781 21145461 24337577 16325183
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
FEM1B CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 18187417 21145461 33961781
DET1 DDA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19295130 17452440 33961781
DDA1 VPRBP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20562859 17609381 19295130 33355139 26344197
DDB1 TP4AP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 16964240 19966799 33961781 26038816 20551172
CUL2 FEM1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32941802 18187417 15601820 33961781 21145461
FBX11 RBX1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17098746 33504946 22113614 33961781
CUL4A CSN7B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 28514442 31973889 18606781 33961781 16964240 21145461 19295130
CUL4A CSN8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 28514442 31973889 18606781 33961781 27173435 16964240 21145461 19295130
CUL4A TP4AP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31973889 16964240 33961781 20551172 21145461
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
CUL4A CSN7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 31973889 18606781 26496610 16964240 21145461 19295130
CUL4A CSN3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16036220 17079684 28514442 31973889 18606781 33961781 26186194 16964240 21145461 19295130
HIF1A CUL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23401859 27320910 19940151 18323857 17439941 17132228
TERA CUL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 22466964 18775313
CSN3 CUL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16036220 28514442 33961781 26186194 21145461 19295130
CUL2 LRC14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 19295130 33961781
CUL2 LLR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 19295130 15601820 33961781
CUL2 CSN7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 19295130 26496610
CUL2 CSN8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781 27173435
CSN3 CUL3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16036220 28514442 33961781 21145461 19295130
CUL1 CSN7B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 29103612 27833851
CUL1 FBX22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31217475 32249768 29103612 21145461 22268729 29945959
CUL1 FBXL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24157836 27383304 25249620 33961781 19762597 19762596 32126207 22268729 24778179
CUL3 KLH24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781 33130828
CUL3 KLH22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27561354 19995937 17543862 33961781 33130828 21145461 19295130
CUL3 CSN7B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 27833851 33961781
CUL3 KLH18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23213400 33292627 33961781 33130828 21145461 19295130
CUL3 CSN4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 19295130 33961781
CUL3 RHBT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26100637 18835386 23040068 33961781 30896450 31431478 21145461
CUL3 CSN7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27833851 33961781 21145461 19295130
CUL3 KLH15 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27561354 33961781 33130828 23135275 21145461
CUL3 BTBD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 19995937 17543862 21145461 19295130
CUL3 KLHL9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19995937 31515271 17543862 33130828 21145461 19295130
VHL NEDD8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16503656 17353931 15060148 18323857 11024059
P53 CARM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29653964 15186775
CSN5 CRBN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 24292625 31950832 27029275
CSN8 CRBN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24292625 27029275
CSN5 DCAF4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 19615732 33961781
CSN6 DCAF4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 21145461 19615732
CSN5 FBXL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781
ASB6 ELOB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31253590 21145461 24337577
CSN5 BTBD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 21145461 19295130
MARE1 CSN5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17350042 31950832
CSN5 FBX7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781
CSN5 DCA11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28446751 31950832 19295130 21145461 19615732
CSN5 TERA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 19826004
CSN5 K1737 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781 26186194
CSN5 PP1G â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21382349 21145461 23080069
A4 GRP78 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32814053 33961781 30664241 33957083
CSN7B CSN7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22863883 33961781
CSN6 DCA11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 28446751 33961781 26186194 19295130 21145461 19615732
CSN6 TOIP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 19615732 19295130
CSN6 RHBT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31871319 33961781 26186194 21145461
CSN6 FXL14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781
CSN6 UBC12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 28581483 33961781
CSN8 DCA11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27173435
BCL3 NFKB1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CUL1 FBXL5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
DDA1 VPRBP â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDK2 SKP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CUL4B DCAF4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DDB2 RBX1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DCA11 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 28446751 31973889 26496610 33961781 31155351 21145461 34026424 16949367
CRBN CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 24292625 31973889 33961781 21145461 27142104 27294876
DDA1 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31973889 26496610 21145461 19295130 16949367
ERCC8 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16949367 31973889 29531219 26496610 33961781 21145461 22902626
TP4AP CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 21145461 33961781 31973889
VPRBP CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22038470 31973889 28416635 26496610 21145461 33355139 16949367
DCAF4 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 28446751 31973889 26496610 33961781 21145461 30945288 16949367 32140073
CUL4B CSN2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 16861906 26496610 33961781 24981860 26186194 21145461
CUL4B DTL â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21628527 17041588 31973889 24962565 23555860 16861906 26496610 33961781 31155351 21145461 16949367
DDB1 DDA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20562859 17609381 17452440 16964240 26344197 19295130 16949367
DTL CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21628527 17041588 23478441 31973889 23555860 16861906 29424068 30623174 31155351 33961781 30649446 21145461 16949367
ERCC8 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16949367 31973889 29531219 12732143 29225035 21145461 16751180 26826127 22902626
DET1 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 17452440 16964240 14739464 16949367
CUL4A NEDD8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16503656 19617556 22474075 18274552 31973889 24654937 16620772 12481031 19295130 23201271 16964240 10597293 21145461 18247557
CUL4A DCA11 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17079684 28514442 27203182 31973889 28453520 32235678 31155351 33961781 16964240 21145461 19295130 30945288 16949367
CUL4A DCAF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 33961781 16964240 21145461 30945288 16949367 32140073
CSN2 CUL2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 26976604 22013077 11967155 26186194 33961781 31444342 21145461 32047038
CSN3 CSN7B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 20399188 27833851 33961781 26186194 24981860 22939629 19295130 32034103
CSN3 MYOV2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 26456823 33961781 26186194 32034103
CSN3 CUL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16036220 19141280 29103612 21145461 19295130
KLH13 CSN2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN2 CUL3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 26976604 33961781 21145461 19295130 16045761 32047038
CSN2 CSN7B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 22863883 27833851 27173435 26186194 33961781 31444342 22939629 26344197 32034103
CSN1 CUL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16036220 19141280 34237211 21169563 29103612 21145461 11337588
CSN7A CUL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19141280 12628923 27833851 29103612 21145461
CUL1 UBC12 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21247897 12565873 18805092 18826954 19245792 17914462 27591266 28581483 28475037 24949976 27348078 21946088
CUL1 CSN4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16036220 19141280 29103612 21145461 19295130
CSN5 SKP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 31950832
NEDD8 CSN1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 27029275
HIF1A GBLP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25959252 25204544 19251694 27320910 23722539 24648344 17244529 17875644
THIO NFKB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7788295 25609649
IKKB CSN5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23636414 19656241 31950832
CSN5 KLH24 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN5 FBX11 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN5 S10A7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 30203426 16713569 15994944 12702588
CSN5 KLH22 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN5 KLH13 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN5 KLH18 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN5 KLH15 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN5 KLHL9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CDN1B UCHL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12082530 16189514
1433Z TERA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23383273 15161933 21988832
KLH13 CSN4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN4 CSN7B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 22863883 27833851 27173435 33961781 22939629 19295130 26344197 32034103
CSN6 KLH13 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN6 KLDC5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN6 KLHL9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN6 FBX11 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN6 KLH24 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN6 KLH22 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CUL4A ERCC8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CRBN RBX1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CSN5 BCL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 10362352
JUN BCL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 10497212
CSN3 CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16036220 28514442 31973889 23238014 26496610 22863883 33961781 24981860 26186194 21145461 19295130
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
CSN5 CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34026424 31973889 23238014 18850735 23357576 26496610 33961781 26186194 19615732 21145461 19295130 30945288
CUL4B CSN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31973889 23238014 28225217 26496610 24292684 33961781 24981860 21145461 19295130
CSN6 CUL5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31253590 33961781 19295130 21145461 19615732 11337588
CSN6 DDA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 19295130 33961781
DET1 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33911083 33961781 31155351 17452440 16964240 14739464 16949367
ERCC8 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16949367 22232169 28416769 29531219 17392787 12732143 31970402 16751180 26826127 22902626
DDB1 DCAF4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19966799 33961781 16964240 30945288 16949367
DDB1 DTL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21628527 17041588 23478441 16861906 29424068 30623174 33961781 31155351 30649446 16964240 33536335 16949367
DDB1 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22118460 20870715 16473935 15448697 16678110 30349055 33504946 16751180
DDB1 CSN1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22767593 33961781 16949367 27029275
CSN6 DDB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16260596 26496610 12732143 33961781 19295130 26186194 21145461 19615732
DDB2 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16260596 28416769 16473935 25628365 26496610 12732143 33961781 30349055 20368362 16751180
CSN6 DTL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 16861906 19295130
CSN6 ERCC8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29531219 12732143 19295130 21145461 19615732
CSN6 FEM1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 21145461 19615732
CSN1 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27029275 30349055 11337588
RBX1 SKP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29499133 18826954 34237211 18667692 19112177 19398581 18239684 33961781 30349055 33504946 11245432 23770852
RBX1 NEDD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16503656 18247557 12481031
P53 TOP2A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32807901 10666337 16713569
CSN1 CUL4A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17079684 31973889 18606781 26976604 27029275 33961781 21145461 22414063
CSN5 CUL4A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17079684 28514442 22474075 18606781 18850735 23357576 22956996 12732143 27029275 26976604 33961781 26186194 19615732 16964240 25349427 21145461 19295130 32047038
CSN6 CUL4A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17079684 28514442 22474075 31973889 18606781 33179082 33961781 19295130 26186194 16964240 21145461 19615732 30945288
CUL4A CSN2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31973889 18606781 32493769 26976604 27029275 33961781 26186194 16964240 25349427 21145461 19295130 32047038
CUL4A CRBN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24292623 24292625 31973889 32235678 23983124 26231201 25860244 26990986 27029275 33961781 16964240 32132601 21145461 27142104 20223979 27294876
VHL CUL2 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6542648 18323857
CSN6 CUL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 19295130 21145461 19615732
CSN5 CUL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18850735 22956996 22013077 19615732 21145461 19295130
CUL1 CSN2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16036220 19141280 26976604 29103612 11967155 21145461 16045761 32047038
NCOA1 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10847592 10567404 16713569 9642216
FBX11 CUL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17098746 23319600 29103612 33961781 21145461 22113614
TERA CUL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26112410 22466964 28443643 18775313
FBX17 CUL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 18203720 29103612 33961781 26186194 21145461
CUL1 CSN8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19141280 29103612 22959436 18173839 21145461
CUL1 FXL14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21145461 29103612 33961781
CDN1B SKP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10559916 16209941 23910095
FBX22 SKP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 31130363 31257023 30596474 17463251 31217475 27705803 26496610 32249768 33961781 29945959 26087183
CSN6 CUL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 19295130 21145461 19615732
CSN1 CUL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27029275 33961781 21145461 11337588
CSN5 CUL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 18850735 22013077 33961781 19615732 29897280 21145461 19295130 32047038
CUL3 BTBD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 19995937 25011449 17543862 33961781 21145461 19295130
CUL3 KLDC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19256485 25011449 33961781 33130828 21145461 19295130 19261606
CUL3 KLH13 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19995937 30190310 33872809 31515271 17543862 33130828 21145461 19295130
CSN6 SKP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21145461 19615732 33961781
CSN5 SKP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34237211 21145461 19615732
CSN6 NEDD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16503656 24654937 25144743 21145461 19615732
CSN5 NEDD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16503656 24654937 25144743 21145461 19615732
NEDD8 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22836579 17098746 15242646 22653443 17369817 21887275 24654937 20101219 22895816 16620772 32807901 22370482 17546054
HIF1A P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15629713 16189514 11593383 9537326 16713569 12124396 31467278 12606552 10640274 27345397
CSN5 BTBD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 21145461 19615732
ELOC ASB6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21145461 19159283 33961781
CSN6 BTBD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 21145461 19615732
CDN1B CSN5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16951171 17951406 28919423 12082530 24671224 18202760 15688030 19139918 15480426 22350412 18285702
CSN5 UCHL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12082530 16189514 16713569
CSN5 LLR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 19295130
CSN5 LRC14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 31950832
CSN5 FBX17 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 21145461 19615732
CSN5 VPRBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18606781 18850735 33961781 19615732 21145461 19295130 33355139
1433Z PABP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 15161933 17361185
HS71L HSP71 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 33957083
HSP71 HSP76 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22863883 22939629 33957083
CSN7A CSN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17403899 19141280 11285227 9707402 10903862 26496610 22863883 26344197 27833851 22939629 19295130 23086934 14647295 11337588
CSN6 ELOC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 19295130
CSN6 FBX7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21145461 19615732 33961781
CSN6 FBX17 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 21145461 19615732
CSN6 LLR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 19295130 21145461 19615732
CSN6 KLH18 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 33961781
CSN6 LRC14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 19295130
CSN6 MYOV2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 26456823 33961781
CSN6 KLH15 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 33961781
CSN6 VPRBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18606781 33961781 19295130 21145461 19615732 33355139
CSN8 CSN7B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 9707402 27833851 27173435 33961781 26344197
KLH13 KLH22 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19995937 33961781 21145461 19615732
NEDD8 RBX1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
SKP2 CDK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 9858587 9636170 25852190 23455922 10559858 19270695 26496610 23602568 16979657 10386600 19686743 15355997 20160477 18604603 22770219 33422522 33961781 26186194 7553852
CDK2 SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7553852 26496610 25852190 33961781 9636170 23602568 16979657 23455922
CDK2 NCOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10660621 21550420 17570479
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
RBX1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33969670 24292684 12481031 25189618 12609982 26496610 30349055 27113764 29499938 19250909 22038470 34026424 28446751 31973889 23238014 33961781 33504946 30945288 32140073
CSN6 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31973889 26496610 22863883 33961781 26186194 19295130 21145461 19615732
CUL4B DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19651607 33969670 33357448 28225217 24292684 25189618 21145461 18593899 26496610 16678110 16964240 33536335 27113764 29499938 30898011 28886238 29738775 17392787 29846670 22939629 22038470 34026424 16949367 31911655 28446751 17041588 23238014 31973889 16861906 33961781 30945288 26344197 32140073
CUL4B DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17041588 31973889 18593899 26496610 30923324 33961781 26186194 21145461 30945288 16949367
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
CUL5 ELOB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24438103 25499913 15574593 21145461 30166453 24076655 23806657 31253590 11384984 16530799 20463065 14564014 17351129 22479405 24402281 24390335 23098073 21119685 24390320
CUL5 ELOC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24438103 21199876 15574593 21145461 30166453 24076655 23806657 31253590 11384984 16530799 20463065 14564014 17351129 22479405 24402281 24390335 23098073 32513959 33961781 24390320
CUL4A DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22952844 17079684 22118460 15448697 26613412 22910413 25349427 21145461 22474075 27462452 16473935 15811626 18606781 26231201 18593899 16678110 16964240 33536335 19295130 25982117 33759138 16260596 27113764 21113133 30898011 28886238 26976604 27203177 17392787 25795299 22939629 26344197 14739464 27294876 10585395 27573245 31911655 17041588 20870715 27203182 31973889 32235678 16861906 19966799 22342275 34251884 17626091 19287380 30945288 16949367 32140073
DDB1 CRBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23983124 29370161 28425720 24292625 26909574 26231201 25108355 25860244 16964240 27142104 24292623 26990986 30190590 27294876 26131937 32235678 29892083 27338790 32132601 20223979
DDB1 DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22118460 28035050 12050362 24249678 26410533 22822215 28416769 29262658 16473935 18593899 30923324 16678110 16964240 20368362 12812979 19295130 16751180 19109893 17360488 16260596 27203177 17392787 10777491 12151405 32985517 14751237 22039351 17041588 12732143 11564863 9418871 19966799 33961781 26186194 34251884 16949367
DDB1 VPRBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21957298 25499532 26613412 30166453 17314515 18606781 28416635 24558487 19295130 30590706 24412650 17609381 27571178 25532805 16949367 28202763 27354282 20870715 25557551 19287380 33355139 26344197
CSN5 DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 16260596 28514442 18850735 26496610 12732143 33961781 32985517 26186194 21145461 19615732
CUL4A DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 28514442 22118460 28035050 11564859 21145461 29262658 16473935 15811626 18593899 26496610 30923324 16964240 20368362 19295130 16751180 33759138 16260596 27203177 17609381 32985517 10585395 17041588 31973889 12732143 33961781 26186194 17626091 30945288 16949367
CSN5 ERCC8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29531219 12732143 21145461 19615732 16751180
CSN5 MIF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 11089976 15757663 26352431
CAND1 RBX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29499133 18826954 12504025 15537541 12504026 30349055 12609982
RBX1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19327355 17183367 12149480 15448697 10230407 12481031 29547696 32296183 11861641 15601820 30349055 22405651 25540389 10579999 19250909 21822215 21778237 29958295 22863883 33961781 33504946 28591624 17132228
RBX1 CUL4A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 16189514 15448697 10230407 12481031 17452440 22474075 11861641 18593899 30349055 19295130 22405651 33759138 30352932 27113764 26976604 27203177 26990986 19250909 27203182 31973889 32235678 29958295 22863883 33961781 33504946 19287380 30945288 32140073
RBX1 VHL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 23401859 33567268 12048197 17353931 15601820 26735018 24469044 30349055 33504946 33137104 12604794 16261165 16325183
CAND1 RBX1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL4A CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 21249194 22474075 12504025 15448697 18606781 31973889 12609982 27203177 12504026 19295130 16964240 21145461 22405651
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
CUL2 ELOB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19327355 24076655 31253590 12149480 15966899 12048197 15601820 25661653 11384984 24981860 18173839 21145461 9122164 30166453
CUL2 VHL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 22086907 28514442 9751722 10823831 15060148 11865071 21942715 27697924 20049704 26743088 11779168 17439941 12604794 9122164 21145461 15611064 19030229 21685897 12048197 10421634 28775317 15601820 10449727 24469044 11384984 10587522 18173839 22286099 17339318 16261165 16611863 23401859 15966899 22234250 9447969 17353931 26751167 18323857 25661653 33137104 11024059 18187417 18523483 10318914 26735018 24981860 33961781 31444342 26846855 17132228
CSN7A CSN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16036220 28514442 20399188 25043011 11285227 10903862 26496610 22863883 27833851 33961781 26186194 24421388 22939629 19295130 26344197 11337588
CSN7A CSN2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25043011 12628923 11285227 10903862 26496610 22863883 27833851 33961781 26186194 22939629 19295130 26344197 11337588
CSN5 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 11818334 24078030 17583730 14993265 27060206
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
CSN5 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 10766246 10903862 25609649 20093369 8837781
CSN6 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22474075 19141280 34237211 29103612 19295130 21145461 19615732 11337588
FBX7 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10531035 15145941 27503909 34060591 27497298 26496610 29103612 16278047 18495667 33961781 21145461
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CSN5 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21903097 21145461 22474075 22767593 26265931 22013077 16036220 21249194 19141280 31950832 24973710 22959436 27774986 29863914 25144743 19615732 34237211 18850735 22956996 29103612
CUL1 SKP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 17704768 12840033 18667692 15456869 18239684 12504026 9636170 12609982 17439941 21145461 10559858 9736735 17438373 23951410 19398581 28614300 22464731 22013077 29137415 30349055 19270694 16774918 18173839 23770852 24085301 21249194 29499133 23868976 22310285 11961546 9430629 32313199 10559916 25143387 20160477 10230406 9663463 22524983 34237211 21119685 33422522 27542266 29103612 16880511
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
FBXL5 SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24157836 16189514 10531037 25416956 27383304 32296183 31167929 24778179 33961781 19762596 21516116 32126207 19762597
FBX7 SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 10531037 10531035 15145941 25416956 27503909 34060591 27497298 26496610 27705803 20596027 16278047 33961781 22632967 24947323 21378169
FBX46 SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 19159283 23658844 27705803 20596027 33961781 22632967
FBX17 SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21640084 25416956 10531037 32296183 18203720 27705803 33961781 26186194
CAND1 SKP1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
SKP2 CDN1B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 23910095 33854235 20663873 12140288 19112177 18239684 23911321 15075339 15735731 27565346 29137415 16774918 12813041 11463388 12042314 24085301 18805092 22310285 19686743 22959436 12529174 22632967 15355997 10559916 20160477 21503567 15469821 22524983 20160482 26450989 32265224 11565034 16209941 21237244
CAND1 SKP2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
NEDD8 UCHL3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 9790970 14673145 16713569
HIF1A ELOB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23401859 31253590 12050673 12004076 19940151 18323857 17353276
HIF1A ELOC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21658608 17558023 12050673 17244529 12004076 19940151 18323857 17353276 17965024
NFKB1 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18498249 17898080
HIF1A GYS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020
IKKB NFKB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 16713569 11297557 11976329 10469655 11158290 22536447 12482991
ELOB VHL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 28514442 10205047 9751722 7660130 10823831 15060148 21942715 20049704 12604794 9122164 14636579 19030229 31253590 10635329 32328410 12048197 28775317 15601820 10449727 17922844 20871634 24469044 10587522 18173839 22286099 17339318 25500545 22234250 12050673 17353931 17986458 26751167 18323857 25661653 30890701 7660122 15935760 12697815 18187417 12004076 26735018 27517496 24981860 33961781
ELOC VHL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 28514442 9751722 10205047 7660130 10823831 15060148 21942715 12604794 9122164 14636579 15611064 19030229 21685897 17558023 10635329 32328410 10421634 28775317 15601820 10449727 17922844 20871634 24469044 10587522 25500545 8674032 22234250 20300531 17353931 17986458 11739384 17244529 26751167 29401731 18323857 25661653 30890701 33137104 7660122 15935760 12697815 18187417 30267325 12004076 26735018 27517496 24981860 33961781 18305400 29121446
CSN6 CRBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24292625 27029275 19295130 21145461 19615732
BTBD2 CSN6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26186194 16169070 21145461 19615732
ERN1 GRP78 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27238082 32149426 26551274 12637535 21118962
CSN7A CSN5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12628923 21145461 20399188 11285227 26496610 19295130 19656241 17403899 31950832 10903862 27833851 22939629 19615732 11337588 18850735 17429597 22863883 33961781 26186194 26344197
THIO CSN5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15480426 21145461 28270496
CSN5 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28539160 11285227 17879958 16936264 24725084 16624822
CSN5 ALR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14500725 16713569 11709497 15304329
CSN5 CSN7B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22939629 20399188 31950832 18850735 22863883 27833851 27173435 26186194 19615732 16624822 31444342 33961781 21145461 19295130 32034103
1433Z P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22653443 9620776 16376338 16713569
UBP7 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22084066 23388826 31492752 17268548 16474402 26238070 30067985 22056774 17525743 21845734 22653443 31666375 11923872 24462112 29748603 29795372 16402859 14506283 20713061 21170034 30651545 16713569 16845383 20816748 17380154 31647545 32587091 23382381 25283148 26460617 32807901 15916963
PLAK CTNA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7890674 9110993 16189514 25241761 9762469 20936779 14517306 34079125 22939629 7650039 26344197
CSN6 CSN7A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17403899 19141280 25043011 10903862 26496610 22863883 27833851 33961781 19295130 26186194 21145461 19615732 23086934 26344197
CSN7A CSN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20399188 25043011 11285227 10903862 26496610 14681455 27029275 22863883 27833851 33961781 22939629 26344197 11337588
CSN8 CSN7A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17403899 25043011 11285227 10903862 9707402 26496610 22863883 27833851 33961781 19295130 23213463 26344197 11337588
CSN1 CSN7B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 20399188 14681455 27833851 33961781 22939629 22414063 32034103
CSN6 CSN7B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22863883 27833851 27173435 26186194 19295130 33961781 21145461 19615732 26344197 32034103
KLH13 KLHL9 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19995937 33872809 31515271 17543862 33961781 21145461 19615732
CUL4A VPRBP â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CUL4A DET1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
NEDD8 SKP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CDK2 SKP2 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CRBN CUL4A â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
NEDD8 SKP1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 16503656 21145461 18247557 27705803
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
VHL ELOB â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 6542648 18323857
CSN5 RENT1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 21145461 26344197
CUL4B DTL â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CUL4A DTL â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
DDB1 DET1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CUL3 RBX1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 19818716 15448697 12481031 11861641 30349055 25270598 20027226 22405651 26100637 19256485 11311237 19250909 25278611 26286618 20865015 15601839 19617556 29958295 33504946 12684064 24145166
CSN4 CSN3 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16036220 28514442 20399188 25043011 11285227 9707402 32034103 22863883 26344197 33961781 26186194 24981860 22939629 19295130 14647295 11337588
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
SKP2 SKP1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6540196 18239684
ELOC ELOB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
DCAF4 DDB1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
FBX11 SKP1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 29892012 25416956 17098746 23478441 27705803 30254149 28614300 20596027 33961781 22632967 22113614
FXL14 SKP1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 32296183 33961781 27705803
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
CSN4 CSN5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 21145461 32034103 20399188 11285227 9707402 19295130 14647295 31950832 16624822 19615732 11337588 18850735 22863883 33961781 27173435 26186194 24725084 23086934 26344197
CSN8 CSN4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 25043011 11285227 9707402 22863883 26344197 27173435 33961781 24981860 22939629 19295130 23086934 14647295 11337588
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
NFKB1 BCL3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 20558726 10362352 17962807 20547759 8428580 10469655 14678988 20800578 15829968 30833792
CDK2 CDN1B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 12972555 25241761 31822694 11940657 33854239 17254967 17254966 17418410 25852190 19139918 15619620 15557281 9192873 23455922 17671428 11521189 19631451 8684460 21423803 26496610 9472014 9311993 18615582 9724724 8978686 23602568 15647383 10198259 27998760 15890360 16326706 27175940 18850315 10323868 17698606 9658399 24632684 15355997 17053782 10585280 10393546 16782892 12417722 9218599 9660939 26450989 24358021 33422522 12529437 9632134 21439954 33961781 26186194 12800980 9380407 18285702
CUL5 RBX1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31253590 18805092 10230407 11861641 14564014 25912140 19250909 30349055 15574593 22405651
DDB1 DTL â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
UBC12 RBX1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 29499133 12565873 18826954 19245792 19549727 28581483 25912140 29958295 19250909 20353940 28475037 21765416 24949976 16275327 11574546 17132228
RBX1 SKP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 12504025 12840033 12481031 26540345 11245432 29507117 10531037 16357137 30349055 15452136 12813041 23770852 29499133 12628165 11961546 29863914 33692209 27705803 33504946 12684064
CUL2 ELOC â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19327355 17183367 24076655 19339690 15966899 23563313 9447969 15601820 10449727 26735018 25661653 11384984 31444342 24981860 21145461 9122164 30166453 29991678
CSN8 CSN3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32034103 32296183 20399188 11285227 9707402 19295130 16036220 19141280 25043011 22939629 11337588 22863883 33961781 27173435 26186194 31444342 24981860 26344197
CSN6 CSN3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16036220 28514442 22939629 20399188 25043011 11285227 32034103 22863883 33961781 19295130 26186194 24421388 21145461 19615732 26344197 11337588
CSN3 CSN5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 21145461 32034103 20399188 11285227 19295130 24421388 16036220 23636414 25043011 31950832 16624822 19615732 11337588 18850735 22863883 33961781 26186194 26344197
CSN3 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16045761 32034103 20399188 11285227 24421388 19295130 16036220 26456823 25043011 10903862 22939629 11337588 22863883 33961781 11967155 26186194 31444342 24981860 26344197
CSN8 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25043011 11285227 9707402 10903862 22863883 33961781 11967155 26186194 27173435 24981860 22939629 16045761 26344197 11337588
CSN6 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 25043011 11285227 10903862 32034103 22863883 33961781 27173435 26186194 19615732 21145461 19295130 16045761 26344197 11337588
CSN4 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25043011 11285227 9707402 10903862 32034103 22863883 26344197 27173435 26186194 33961781 31444342 24981860 22939629 19295130 16045761 14647295 11337588
CSN5 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 23408908 21145461 16045761 32034103 20399188 11285227 19295130 25043011 31950832 26976604 10903862 16624822 22939629 19615732 11337588 18850735 22863883 33961781 27173435 26186194 26344197
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
SKP2 SKP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 18667692 15456869 30254149 18239684 20041211 16275325 12609982 10559858 23911321 26087183 18818696 23261596 31467278 9827542 10918611 19398581 28614300 22464731 29137415 16376880 15452136 19270694 26474281 12813041 34080260 23770852 24085301 29499133 30728155 17463251 23868976 22310285 11961546 9430629 11099048 22632967 10559916 20160477 15469821 22524983 10531035 34237211 29997244 27705803 33422522 33961781 32350066 16880511 27220724 15070733 15342634
UBC12 NEDD8 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 28514442 25416956 10207026 16735510 16620772 23201271 10828074 21145461 19245792 24654937 21765416 18274552 17353931 19713960 28581483 30804002 23936405 18652489 18264111 33961781 9694792 23267066
HIF1A VHL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15082527 11865071 11226425 10944113 14556007 11986208 15527772 17973296 12538644 26735336 24899725 12606543 21358672 24015760 16611863 23401859 18062927 21332579 15805242 19940151 12086861 27281823 23413029 33060856 11292862 24316222 16155211 24857547 22932900 29121446 11292861 12101228 15060148 18047470 16278378 21602890 27320910 12464182 26611735 32589900 18402654 25500545 12050673 18694926 26215701 10878807 25361009 11641274 22351759 34007068 18305400 21316481 11024059 34195792 26037477 34174286 33039559 10823831 26743088 31810986 10353251 15833858 17558023 11566883 23580587 27563096 18985005 19123984 25438054 12682018 18323857 23387829 17442832 33550096 18222538 18426857 17047048 12004076 34230460 23318261 33961781 12808024 21335603 12586829 17353276 11358837 28514442 20724477 16140212 12205091 20049704 16862177 11331613 32535973 15721254 14691445 15385570 10973499 15611064 17981124 28775317 12925778 26496610 17339318 30237125 20458141 20639890 17986458 19147576 28425505 11504942 22369643 18264140 16511565 12351678 14600153 30988076 17132228
CSN8 CSN5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 23636414 20399188 25043011 31950832 11285227 18850735 9707402 33961781 27173435 19295130 26186194 21145461 19615732 11337588
CSN1 CSN5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 27029275 14681455 21145461 32034103 20399188 11285227 23926101 24421388 22414063 25043011 31950832 19444310 16624822 19615732 11337588 18850735 33961781 26186194 26344197
CSN1 CSN4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11114242 25043011 20399188 27029275 14681455 22863883 33961781 22939629 19295130 22414063 26344197 32034103
ELOC ELOB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 10205047 25416956 12149480 20211142 23333304 21516116 30166453 23988114 32296183 31253590 19159283 10449727 17922844 10587522 12050673 9447969 17997974 11739384 29401731 24402281 7660129 22939629 21822215 10224134 12004076 22863883 24981860 31444342 16675548 26344197
CSN6 CSN1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19141280 25043011 20399188 11285227 27029275 14681455 32034103 33961781 26186194 24421388 21145461 19615732 22414063 11337588
CSN8 CSN1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19141280 25043011 20399188 11285227 9707402 27029275 14681455 32034103 22863883 33961781 27173435 12324474 24421388 22414063 26344197 11337588
CSN8 CSN6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 25043011 11285227 9707402 32034103 22863883 33961781 27173435 19295130 26186194 21145461 19615732 26344197 11337588
FBXL5 SKP1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CAND1 RBX1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CUL4B RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CUL5 RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
DDB1 ERCC8 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CRBN DDB1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
DDB1 VPRBP â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CUL4A RBX1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RBX1 CUL1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 12504025 20832730 15448697 10230407 19933270 12840033 12904573 18723677 12504026 12481031 17452440 12609982 26540345 27697867 22474075 11245432 22767593 28152074 22822056 19245792 12706828 11861641 20399188 10748083 11956208 11483504 27910872 16759355 30349055 10713156 11027288 21765416 20638939 22405651 23770852 19942853 10648623 12565873 18826954 18805092 32145688 21169563 27591266 22660580 11961546 32313199 15361859 19250909 29863914 24949976 10230406 32726803 30653357 32015321 33692209 16123592 34237211 29958295 29103612 33961781 33504946 12684064 26725323 26344197
CSN1 CSN3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 27029275 14681455 32034103 20399188 11285227 24421388 22414063 16036220 11114242 19141280 25043011 10903862 22939629 11337588 22863883 33961781 26186194 31444342 26344197
CSN1 CSN2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 27029275 14681455 16045761 32034103 32296183 20399188 11285227 24421388 22414063 11114242 19141280 25043011 10903862 22939629 11337588 22863883 33961781 26186194 31444342 26344197
CSN6 CSN5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 12220626 21625211 21145461 32034103 20399188 11285227 19295130 19141280 25043011 31950832 25144743 22939629 19615732 11337588 18850735 22863883 33961781 27173435 26186194 26344197
APBB3 A4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 16189514 12153398 14527950 20205790 32814053 9461550 10081969 33961781 31413325
CSN6 CSN4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 21145461 32034103 32296183 11285227 9707402 19295130 14647295 19141280 25043011 22939629 19615732 11337588 22863883 33961781 27173435 26186194 31444342 23086934 26344197
CUL3 RBX1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
DDA1 DDB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CUL2 RBX1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
BCL3 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11387332 24459141 14573596 7896265
BCL3 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17962807 10453354 16108830 11931770 16513645 8428580 8330739 17561400 10362352 9218802 21912613 17183360 14678988 18668140 10469655
SKP1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7553852 23602568 16979657 9636170 26496610 25852190
CDK2 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 7553852 20160477 23602568 25271736 18239684 28446188 23226679 10386600 19270695 26496610 16189514 25852190 26186194 25788262 9858587 22770219 15355997 10559858 23807222 22311674 16979657 9636170 19686743 19270694 18604603 23455922
RBX1 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
ERCC8 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC8 DDB1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 DDB2 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 CAND1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 21463634 12504026 12609982 23535662 21863050
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 DDB2 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB2 DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 54.0 1.0 Omnipath 9418871 17145710 16751180 27203177 22118460 17041588 20368362 18593899 16964240 12050362 19295130 22039351 11564863 16473935 16678110 17392787 24249678 19109893 12151405 26186194 12812979 16949367 18936169 22822215 14751237 10777491 26410533 16260596 19966799 17360488 12732143
RBX1 DDB2 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
RBX1 DDB2 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DTL CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21145461 19231300 16949367
RBX1 ERCC8 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
ERCC8 CUL4A â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
HIF1A MIF â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824
HIF1A MIF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19828020 20606117 17998063 20727156 16854377
CUL1 RBX1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
NFKB1 RBX1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
RBX1 SKP1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 SKP2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
RBX1 HIF1A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 11292861 9122164 10878807 12821933 12101228 11292862 10823831 11504942 11454738 10944113 11358837 11024059
RBX1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CAND1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 26632597 21463634 12504026 12609982 23535662 21863050
RBX1 CUL3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 CUL1 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 CUL2 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 CUL3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 CUL2 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 CUL1 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 SKP1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 SKP2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
RBX1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 154.0 1.0 Omnipath 17053147 12684064 20638939 11967263 19797085 19258535 26540345 18826954 15071497 15448697 21765416 25730849 10230406 23343194 21169563 22270359 19250909 23732914 11359933 12051714 20006983 15361859 10748083 19352404 22682247 18787170 12504025 18636226 16469695 15459660 20211143 10535940 15001769 26725323 19411070 11861641 26159692 16697054 1570337 19751508 22822056 11348595 7542250 7641885 19849719 16759355 12820959 17452440 19622404 15703371 10648623 19245792 23331499 9694792 19150432 23180781 19597341 16189514 22474075 18988627 22767593 17143292 24949976 10713156 23770852 22405651 19942853 18196958 20399188 16713974 26192618 11027288 17884153 19933270 22730322 21411632 11961546 17936032 19809470 15147722 19270156 19576224 11483504 20976471 12504026 24023259 12840033 15340381 12904573 20558317 11900249 14536078 19686080 12565873 18805092 15489953 19557001 26885856 17652783 12481031 20843316 11955436 21071413 16039586 11956208 20705860 8666229 17928543 10023660 19836308 16940750 12706828 19143635 15688063 10671552 16123592 19366350 19847258 12417738 11245432 20832730 12648680 12609982 19619488 10230407 18931676
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
CUL2 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
CUL2 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
CUL2 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
NFKB1 CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
CUL1 SKP2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 SKP1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 14685242 16189514 17290223 20832730 12504025 12904573 10230407 19933270 23324393 12504026 9636170 26540345 12609982 27697867 26753747 21145461 22474075 28007894 18818696 9736735 9990852 22767593 28152074 10023660 29070679 9827542 23951410 16357137 16759355 10713156 15452136 19270694 11027288 26474281 23770852 10648623 29499133 21249194 34499862 12628165 15966899 21169563 22660580 11961546 9430629 32313199 29863914 10230406 30653357 19945379 9663463 21778237 34237211 18094045 26976582 27705803 32249768 29103612 33961781 12684064 26725323
CUL1 SKP2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
NFKB1 SKP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
SKP1 SKP2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
SKP1 CAND1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 26632597 21463634 12504026 12609982 23535662 21863050
SKP1 SKP2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
ELOC HIF1A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 11292861 9122164 10878807 12821933 12101228 11292862 10823831 11504942 11454738 10944113 11358837 11024059
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
NFKB1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 17272744 18393939 21725609 23178297 23572150
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704