SEC61B
|
XBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
ATF6
|
SEL1L
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17967421
|
BCL2L11
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
BCL2L11
|
BAX
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
P4HB
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TP53
|
BCL2L11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19427386
20124456
|
MYC
|
BCL2L11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16169462
21899728
|
MYC
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12209154
|
UBC
|
COPS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7229502
19214193
|
COPS5
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18926707
|
MAP3K5
|
DAB2IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12813029
5216473
|
ERN1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6542966
18369366
|
ERN1
|
XBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18471544
|
HSP90AA1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AA1
|
RIPK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TP53
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17184779
5219502
|
HSPA5
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA5
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA5
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TP53
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11350971
10984493
|
UBC
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7104155
19343052
|
JUN
|
MAPK8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
UBC
|
JUNB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7104155
19343052
|
PSEN1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19012753
18996842
|
SEC61A1
|
XBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
TRAF2
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TP53
|
STUB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21478269
17666403
|
SYVN1
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17170702
5219455
|
RNF13
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
HSP90AA1
|
MAP3K5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
ZNRF4
|
ERN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CSN5
|
UBP14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31950832
18624398
|
CSN5
|
GRP78
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
18850735
21145461
|
ERN1
|
UBP14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24951540
19135427
|
ERN1
|
SE1L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26551274
19135427
|
NTAQ1
|
ERN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
NTAQ1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
MYC
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
20232342
|
SEL1L
|
OS9
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
29496332
|
ERN1
|
CSN5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
15234121
17951406
|
PSEN1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
SEC61A1
|
SEC61B
|
â—¼ CORRELATES
|
|
+
|
0.83
|
0.83
|
CCLE
|
31978347
|
RIPK2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
18329614
9642260
21097508
16189514
|
SEC63
|
GRP78
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26085089
33957083
|
ERN1
|
M3K5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25241761
25797626
12050113
|
M3K5
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
17724081
31077413
10523862
10921914
9774977
32445435
|
SYVN1
|
DERL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16186510
29743537
16289116
24807418
23867461
19864457
26471130
|
MAPK8
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
7148309
19527717
|
OS9
|
SE1L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
24899641
23356641
19084021
19346256
18711132
28827405
26551274
29496332
18502753
23867461
23097496
21454652
22119785
18264092
|
MYC
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21150319
16996503
19131971
|
TRAF6
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
8153045
21516116
|
TRAF2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
SEC24C
|
SEC24D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
COPS5
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
MAP3K5
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ERN1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
MAPK8
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
SE1L1
|
SYVN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23356641
18711132
26424800
28827405
32614325
31477895
29496332
18502753
24807418
23867461
24366871
26471130
21454652
16186509
21903092
22119785
18264092
|
SYVN1
|
ERN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
26551274
18369366
19135427
26254280
|
RIPK2
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21903422
9705938
16713569
32707033
16189514
|
ERN1
|
SYVN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
SEC24A
|
SEC24D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
STUB1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
BAX
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
DERL1
|
SYVN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
SEC24A
|
SEC24C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
NMI
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9781816
11916966
8668343
10597290
|
CSN5
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20093369
10766246
25609649
10903862
16713569
8837781
|
ERN1
|
GRP78
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12637535
26551274
27238082
21118962
32149426
|
GRP78
|
PDIA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24189400
22939629
33957083
30021884
|
M3K5
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25098452
17015619
18776134
19805025
15310755
17724081
16636664
10523862
9774977
16713569
32445435
29644863
|
ATF6
|
SYVN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20160352
17967421
18664523
|
ATF6
|
XBP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24269637
20003459
12949534
|
HSPA5
|
ATF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18624755
31226023
|
ERN1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18471544
27009865
|
HSP90AA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
MYC
|
HSP90AA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
28914785
12644583
|
TP53
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15212714
20097177
18840615
|
TP53
|
SYVN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16980608
|
TAOK3
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
16713569
11278723
|
TRAF2
|
RIPK1
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
10795740
|
TRAF2
|
RIPK1
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
18621737
|
TRAF6
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
HSP90AA1
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
RIPK1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
BAX
|
BCL2L11
|
â—¼ PROXIMITY
|
✅
|
|
0.94
|
0.94
|
mint
|
7034061
19427863
|
JUN
|
JUNB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
25609649
28514442
33961781
|
SEC61B
|
SEC63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
ERN1
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
UBC
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17568776
5220017
|
OS9
|
SEL1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
OS9
|
SYVN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
SEC61A1
|
SEC63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
SEL1L
|
SYVN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
DAB2IP
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
UBC
|
USP14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
DAB2IP
|
MAP3K5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
SEC61A1
|
SEC61B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
JUN
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MYC
|
NMI
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
17145710
10597290
8668343
17093053
9781816
11916966
|
ATF6
|
SYVN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
17991856
18360008
23850759
26587781
|
ATF6
|
SEL1L
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
17991856
18360008
23850759
26587781
|
ATF6
|
DERL3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
17991856
18360008
23850759
26587781
|
ATF6
|
XBP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
17991856
18360008
23850759
26587781
|
ATF6
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
19667116
22189555
10856300
19622751
20165829
10866666
17117415
12076252
14973138
15899857
17241871
20801537
11256944
16452489
17522056
10564271
12713871
|
BAX
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
20709625
21641962
22039431
23064052
23377657
23430059
23850759
26587781
7644501
8358790
|
BCL2L11
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10198631
12419244
15486085
15724238
23430059
23850759
9430630
|
BAX
|
TRAF2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
20709625
21641962
22039431
23064052
23377657
23430059
23850759
26587781
7644501
8358790
|
TP53
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11278953
12203124
16931621
9582019
17693666
11118038
12433990
11395510
8183578
11429705
10400708
15242522
11423991
19067706
24336083
18381427
22732402
15988033
16341121
10935506
10094833
16215989
17280505
10744634
12851404
20673369
15851483
8845569
10559267
12168779
11850816
19505426
8564971
11756653
19054058
15566940
12173040
17690113
8635454
18034190
10510469
10101800
11335718
23100276
9400998
9445173
9582400
24098340
22532570
9122197
11420692
11104574
15679092
11748232
12560513
11928223
20400479
20546728
17145718
20567883
20840522
18172861
10566557
10777477
7834749
12806965
17521288
19242108
9000137
21859835
|
MYC
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8845569
11103792
12695333
|
MAPK8
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15525785
18471544
16709574
|
TP53
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14963330
16151013
7834749
|
BCL2L11
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22492984
26186194
17289999
12419244
11301022
12198137
17525735
21199865
18948948
23235460
11997495
15486085
12242151
23374347
19427863
15721256
|
JUN
|
BCL2L11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17702754
16153157
23285061
22869147
21439021
|
MAPK8
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
15486195
14555991
18691976
22071694
12591950
15470142
18174237
18498746
12818176
|
COPS5
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
25609649
20093369
18926707
10766246
16713569
8837781
|
TRAF2
|
DAB2IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
10734135
15310755
18292600
8974401
|
RIPK1
|
DAB2IP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
11274345
17389591
18641653
19498109
19524512
19524513
19632174
21133840
21232017
23010170
26587781
26653790
28574505
|
RIPK1
|
DAB2IP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
27858941
15310755
17389591
|
DAB2IP
|
MAP3K5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18292600
9774977
12813029
27858941
15310755
|
TRAF2
|
ERN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11274345
15592525
17462996
18641653
19392652
21133840
21232017
23850759
24378531
|
HSPA5
|
ERN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18624755
26551274
31226023
12637535
|
ERN1
|
TRAF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
25797626
25241761
18519638
11278723
12843613
25225294
16713569
10650002
|
TP53
|
HSP90AA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15358769
15284248
24451373
18996350
|
HSP90AA1
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10744744
17145710
12441346
14743216
|
HSP90AA1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
12427754
10557093
21460846
16713569
11507088
|
JUN
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
40.0
|
1.0
|
ACSN
|
11274345
11929833
11955436
11967263
12051714
15001769
15576399
15768032
15806138
16007074
16039586
16169192
16510874
17050667
17143292
17291450
17439715
17936032
18347071
18627596
19619488
19623618
20006983
20122174
20530697
20705860
20920541
21285352
21767405
22290435
22705350
22761862
23306204
23343194
24023259
25730849
26587781
7542250
8545107
8666229
|
JUN
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21835891
8276360
1774959
2498162
21607323
20410304
14523011
18037408
|
JUN
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22859294
17321721
20697347
10348347
12963547
10072388
22353755
18604200
|
JUN
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
9256279
11204570
11353786
23274526
11678207
17341624
20015448
8910439
16328781
11731421
15039660
19553068
20432243
7887961
12163680
10885623
11281649
14602779
18294451
15277220
|
MAPK8
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
202.0
|
1.0
|
Omnipath
|
17143273
17804415
10617656
8846788
15958389
11948398
10882101
20028971
12697749
15894542
20514406
14612408
17875713
9891069
17570479
18922473
11809792
8586671
11896587
12185592
12871843
7992057
7600582
11278395
8137421
8001819
10493750
14557262
16549498
18707149
9169478
11460167
15289320
8157646
16007099
20506250
22110360
15378002
9687508
12740383
20732415
9305638
19270716
23331499
10747973
16291755
16393692
12832416
18988627
10713700
18669648
12087092
14633987
8525045
15677475
16076903
16166642
18650425
15590691
1608942
19910486
18212344
11562357
12228228
16740711
14701799
19690332
10871633
12531896
16713569
8654373
16983342
19664995
15302935
10962563
15068801
8621542
8607977
18362184
10393177
20068231
9808624
14572659
8224842
10585392
9407028
17363973
19527717
19436832
14517282
12407442
9487126
9692890
14523011
15212693
10908726
11108663
13130464
10064600
18429822
15299005
9774977
11907583
12963725
16824735
19413330
10617104
17055484
21071413
18452278
16434970
16157600
7737130
23816567
10987838
17189706
9561845
9575168
1460037
7652575
18617513
24113186
11971971
11801649
25098452
20058876
16533805
9184210
18003900
9315636
10385525
18957422
12881422
11274345
12052834
15749833
|
JUN
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
15806138
16510874
22290435
18627596
19623618
11929833
23343194
15768032
22761862
17050667
16039586
20122174
17291450
20920541
17143292
20006983
17439715
15576399
21767405
23306204
8545107
22705350
18347071
16007074
16169192
21285352
20530697
19619488
11274345
|
MYC
|
JUNB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
2123531
7775604
12695333
18838534
18414489
|
MAPK8
|
JUNB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8917518
18669648
9889198
20068231
9405416
|
TRAF2
|
MAP3K5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
14730360
15592525
17462996
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
|
RIPK1
|
MAP3K5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
14730360
15592525
17462996
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
|
RIPK1
|
MAP3K5
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
14730360
15592525
17462996
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
|
TRAF2
|
MAP3K5
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
14730360
15592525
17462996
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
|
TRAF2
|
MAP3K5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
10688666
18292600
9774977
10523862
16636664
19805025
16713569
17700517
17015619
17724081
15310755
|
TRAF6
|
MAP3K5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18292600
9774977
10523862
10921914
17724081
15310755
|
MAP3K5
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
17634293
20348951
15247305
21785467
12194869
12221076
18818208
18029441
19667122
21726807
16760468
21212517
19749799
26147002
25310587
33573023
26375285
16648474
15944157
7839144
12456653
25915038
26853469
21856198
31575661
10521505
25702873
19029119
20156337
16928747
15020250
20452983
15242986
18570871
16845370
20871632
21040800
27203743
19783996
21931634
23608534
21697492
25619840
26964622
12758252
16632641
28881794
17210579
34048499
20921231
|
TP53
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22607268
23376463
18374905
15958553
10854211
22353755
|
RIPK2
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15692051
17947236
17965022
17186025
26538579
|
TRAF6
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10346818
17965022
15692051
17947236
|
MAPK8
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
11108663
12531896
16713569
11283254
10706102
19651615
27147566
9724739
15538975
9732264
10581258
10436023
17570479
9393873
11896587
12514174
15580310
18813780
11078726
|
MAPK8
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
19651622
10551811
17081983
18767875
20068231
91332050
1651323
1748630
16713569
11243879
18669648
15210690
|
MYC
|
VEGFA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10432118
11274345
11283614
11875494
16327802
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21093321
21372296
21406394
21765015
2191300
22067385
22461508
23124025
23390297
25002027
|
MYC
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19738061
19147754
17785433
22002305
18809243
19398483
12368264
23028984
|
MYC
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10962037
10656696
8494784
10348347
19882681
16557594
19086036
15780936
14519204
16112647
11781835
7969121
11789587
9839551
|
TRAF2
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
92.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11668179
11875494
12048245
12215447
12556535
12646658
12655147
12702723
12724420
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17496911
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21614932
21826665
22427918
22955274
23010170
23069999
23070005
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
28765050
8910423
8974401
9379049
9488730
9582321
9759866
|
TRAF2
|
RIPK1
|
â—¼ SHARES_COMPLEX
|
|
|
92.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11668179
11875494
12048245
12215447
12556535
12646658
12655147
12702723
12724420
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17496911
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21614932
21826665
22427918
22955274
23010170
23069999
23070005
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
28765050
8910423
8974401
9379049
9488730
9582321
9759866
|
TRAF2
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
92.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11668179
11875494
12048245
12215447
12556535
12646658
12655147
12702723
12724420
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17496911
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21614932
21826665
22427918
22955274
23010170
23069999
23070005
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
28765050
8910423
8974401
9379049
9488730
9582321
9759866
|
TRAF2
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
8702708
8612133
25416956
16713569
18621737
25882049
16291755
18981220
21741934
21232017
20577214
11181075
10795740
23972990
21119000
15175328
20203691
21810480
21282461
9712898
32296183
23007157
25716317
20448643
12887920
24735611
15258597
24434549
19815541
16603398
11479302
9020361
|
TRAF2
|
RIPK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16713569
9705938
21903422
|
SYVN1
|
SEL1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
ACSN
|
12847084
16186509
18199748
18360008
19509052
|
SYVN1
|
SEL1L
|
â—¼ SHARES_COMPLEX
|
|
|
5.0
|
1.0
|
ACSN
|
12847084
16186509
18199748
18360008
19509052
|
TP53
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
8108142
20639906
9377555
21325822
16684540
9833779
10910082
16835303
23449391
8521408
15860260
11971180
11559575
|
TP53
|
BAX
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.43
|
1.42
|
PKG
|
28854368
|