Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PRKN PUF60 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20418918
P4HB ERO1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20802462 8075064
ERO1A PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
ERO1A P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212958 10970843
P4HB COL10A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211722 10436013
FEZ1 P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FEZ1 PTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
P4HB CCDC26 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ANKEF1 P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APOB MTTP â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8626595 14732096
P4HB BBS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VWF BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16581250 8649368
ITGB3 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16581250 8649368
P4HB BCL2L11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
PAK2 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20936779
CALR YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PDIA2 CALR â—¼   COLOCALIZATION 2.0 0.8 intact 23167757 8401719
CAPN2 P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
P4HB CEP76 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEP76 PLK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
COMP ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20033473 32196115
PPIB CPSF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PER1 CSNK1E â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10790862 11165242
DDIT4L P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PDIA3 EFEMP1 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
HSPA5 ERN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18624755
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
ESR1 GNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19170076 18414489
ESR1 LCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 21741997
P4HB F3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0606411103 16959886
P4HB FASTKD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRN FASTKD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB1 P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
P4HB GPX7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23454490 21215271
P4HB GPX8 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23454490 21215271
INS GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12493740 14615605
IGF1R GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547677 9506989
LCE1B GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRN PER1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HIF1A HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19071119 6802010
HDAC6 HSP90B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19158084
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
HIF1A ITGB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 23640055
HM13 P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19942855 7718394
HSPA5 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 15146195
YWHAZ IGF1R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547842 9581554
VHL IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17486080 19509240
PER1 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL42 UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRT6A P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
P4HB LRRC18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NCK1 MYLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PAK2 MYLK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10748018 10092231
NCK1 PDIA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
OTUB1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
P4HA2 P4HA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TNXB P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SLC22A17 P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RBBP4 P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PTN P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
P4HB PGAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
P4HB PER1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
P4HB PRPF4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
P4HB SH3KBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
P4HB SHH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21357747 21257310
P4HB PPFIBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
P4HB PLK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
P4HB PDIA2 â—¼   COLOCALIZATION 2.0 0.8 intact 23167757 8401719
P4HB PRDX4 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
YWHAZ PAK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PRDX4 PDIA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
PRDX4 PDIA6 â—¼   COLOCALIZATION 2.0 0.8 intact 8090267 21057456
PRDX4 PDIA6 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
UBQLN1 PER1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ PPFIBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PRKCZ VHL â—¼   COLOCALIZATION 2.0 0.8 intact 5219754 17350623
YWHAZ PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10620507
RBBP4 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KRTAP4-11 TGFB1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
NCK1 PAK2 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CUL3 KLHL42 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
H2AX CALR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20000738 16522924
BACE1 PDIA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15606899 20354142
BCAR1 P4HA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28007913 33001583
BMI1 PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
TAP1 CALR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17055437 11823531
CFTR PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31324722 17110338
CFTR PDIA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
LRFN4 CISD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CPSF3 P4HA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
GPX7 RIPK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRFN4 TRIP6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOX2 RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23667531 21532573
LCE1B LCE2D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
ERO1B ERO1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PDIA3 ERO1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20802462 17170699
ARRB1 IGF1R â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33158816 21685939 15878855
BCAR1 NCK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22974441 12135674
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
ESR1 PDIA6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 31527615
SOX2 PAK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
IGF1R INS â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MAP3K7 RIPK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KRTAP4-11 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
ERO1L P4HB â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
APOA1 APOB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19164805 7592581 28183703
KRTAP9-8 LCE2D â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
APOA1 APOA2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10722751 3104518 24981860
CALR APOB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12397072 10513896 9694898
CASP9 CASP3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 1067155 11242052 11230124 18723680 25241761 15941357 17437405 8900201 15507451
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MTTP P4HB â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CSNK1E PER1 â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 15917222
P4HA2 NEK7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 27173435
PPIB CALR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24981860 30021884
CUL3 PDIA6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26949739 21145461
HIF1A CUL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23401859 27320910 18323857 17439941 17132228 19940151
PPIB APOB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12397072 16713569
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
LRFN4 NCK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22677168
GABARAPL2 ZBTB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CPSF3 SYMPK â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PDIA6 PRDX4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
BCAR1 TRIP6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14688263 16713569 11782456
CFTR GRN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26618866 29924966 17110338 31324722
KRTAP4-11 LCE4A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
PUF60 U2AF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
GRB10 INSR â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
INS IGF1R â—¼   PHYSICAL_INTERACTION ✅ + 0.88 0.88 Signor 1851182
P4HA2 P4HB â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
GRB10 IGF1R â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
VHL CUL2 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6542648 18323857
PAK2 NCK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 11160719 16374509
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
LCE1B LCE4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CALR P4HB â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
P4HB COL1A2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9545296 3173483 9560306
H2AX OTUB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
ATF2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17258390 22542937 15546613
CAPN2 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16998475
PDIA3 CALR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 26344197 12052826 10436013 11823531 16189514 30021884
SMARCB1 CALR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR1 CAPN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
ESR2 CAPN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
COL3A1 P4HB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9545296 3173483 9560306
ITGB3 COMP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16051604 20033473 15345499
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
ESR1 LGALS8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
F10 F3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 3527261 3275472 6980899
YWHAZ GABARAPL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRDX4 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
P4HB IL12B â—¼   ISOMERIZATION ✅ 3.0 0.9 Reactome 25259790 11054122 7527811
INS P4HB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25091901 31184304 21308844
VWF ITGB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
LCN2 SLC22A17 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16377569 15531878 12453412
LCN2 SLC22A17 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16377569 15531878 12453412
PAK4 YWHAZ â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
U2AF2 PUF60 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32296183 26344197 17353931 22365833 22939629 10866799 16169070 16713569 25416956 16189514
MAPT YWHAZ â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
YWHAZ BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217040 15161933
KRTAP12-3 KRTAP13-2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP4-11 LCE1B â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP4-11 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP9-8 LCE1B â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP9-8 LCE4A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
SOD1 SOD2 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
KRTAP5-9 LCE1B â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP12-3 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP5-9 LCE4A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP5-9 LCE2D â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP12-3 LCE2D â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP5-9 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
ERN1 HSPA5 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
KRTAP12-3 LCE1B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
BRAF MAP2K2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
KRTAP12-3 LCE4A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HuRI 32296183
CSNK1E PER1 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CPSF3 FIP1L1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
INS INSR â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
FIP1L1 SYMPK â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
BRAF YWHAZ â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CPSF3 SYMPK â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ESR1 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11013347 18005483 9535920 17532863 23293065
P4HA2 COL1A2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HB COL1A2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A2 P4HA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A2 P4HA1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A2 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1693626
P4HB ERO1B â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 6.0 1.0 Reactome 25091901 21091435 11707400 16407158 21145486 20308425
GPX8 ERO1A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 21215271 23164639 18358825 16401067
ERO1A GPX7 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 21215271 23164639 18358825 16401067
P4HA1 COL10A1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL10A1 P4HA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HB COL10A1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HA2 COL10A1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
CUL2 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
CUL2 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
CUL2 BCL2L11 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17884153 18420585 18931676 19622404 19622774 19686080 19809470 19847258
CUL2 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
CSNK2A2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877451
ATF2 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10909971 17337306 21278380
FGFR1 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11019781 12601080
CASP3 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11511102 11447317 10712510
BRAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 15342917 18039929 19541618 7706312 15466476 25600339 7731720 16135787 17563371 33226073 8668348 17667937 16255777
BRAF YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 17353931 8668348 15324660 15161933
CALR PDIA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
CASP3 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9712143 9171063 11070003 9786869 16204230
CASP3 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12888622 16606369 22535953 11162250
MAP2K2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12792650 18669648
PRKCZ CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16287866
P4HA2 COL1A1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A1 P4HA1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A1 P4HA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A1 P4HB â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HA2 COL3A1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL3A1 P4HA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL3A1 P4HB â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL3A1 P4HA1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
CSNK1E PER1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 11865049 23555304 15148313 10848614 15917222 26496610 16189514 16750171 23455922
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
HIF1A CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19830694 21887463 19212630 20869949 17075581 17083723 20102637 20007689 16840440
HIF1A ENO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 8955077 15459207
HSPA5 ERN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18624755 26551274 31226023 12637535
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
ESR1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20616010 20068169 16950141 21029304 19433249
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
IGF1R GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19165858 8776723 8764099 8621530 12697834 9506989
INSR GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9506989 15664450 10871840 8621530 9006901 19648926 7479769 12783867 12493740
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
HIF1A INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14612449 11457733 18752464 17878221
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
HIF1A TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16896927 17053163 15611046 19211927 21209004 21057546 21055290
HIF1A HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19828020 15620698
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704
INS IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 1851182 18988627
IGF1R YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 16931767 9581554 12175651
KLF11 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17479246 15774581 19122346 21592955 18593768 22801105 20060466 18199129
INS INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8393875 21743783 21317886 24296476 26374090 29069585 26245346 16956584 19902173 20332342 23363978 23331499 18988627 23302862 22832498 2550426 15870194 11278498 19752148 29512653 23304064 24633815 17227660 22521887 23223021 30197476
RIPK1 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
PAK2 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 2160950 18088087 10748018
NCK1 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16374509 11278553 32296183 11160719
P4HB P4HA1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HA2 P4HB â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
P4HB P4HA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
VCP SHH â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19002207 21357747 18502753 18711132 18264092 23867461
VWF YWHAZ â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8034572 9425086 10627461 8631758