Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
PDIA6 GNMT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 SLF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MC4R PDIA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
PDIA6 GOLM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 RPL37AP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 ANKRD45 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PARK7 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP1LC3B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PDIA6 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90B1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP2K2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR2 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15040833 16675543
CASP8 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10409650 10911620
ATF6 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9837962
PDIA6 ATG2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FN1 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16581250 8649368
PDIA6 BEND3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
PDIA6 DMXL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 DNHD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 DNHD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 DPEP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
HSPA5 ERN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18624755
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
ESR2 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22016564 19366879
NR3C1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16303956 3611064
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN RIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GABARAP HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAP1LC3B GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
P2RY6 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC5 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23899560 22991226
HDAC6 HSP90B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19158084
PA2G4 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PDIA6 IGFBP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MTNR1A MTNR1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20859254 8087006
PDIA6 MTRF1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 MYCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYCBP2 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PDIA6 OR51F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
OTUB1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19996094
P4HB SH3KBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
P4HB PRDX4 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
PA2G4 PDIA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 PLEKHO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 PRKAG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 ZNF281 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 SUN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 USP47 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 RGS22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA6 SART3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRDX4 PDIA6 â—¼   COLOCALIZATION 2.0 0.8 intact 8090267 21057456
PRDX4 PDIA6 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
PARK7 PRKN2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15525661 24242043 17846173 19229105
OTUB1 TRAF6 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20622874 34591986 19996094
BCAR1 FYN â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CASP8 TRAF6 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
RIPK4 CUL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26972000 29435596
PTPRN GRP78 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27880917
DPEP3 GRP78 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PRDX4 GRP78 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32457219 33957083
GRP78 PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 33957083
PDIA6 DNJC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 33957083
AGR2 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
AGR2 PDIA6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
AGR2 PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
BMI1 PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CUL3 BTBD9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33130828 21145461
ESR1 CAND1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
CFTR PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31324722 17110338
CUL3 CUL5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22709582 21145461
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
EP300 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 33742100
ESR2 SART3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 29509190
PDIA6 ISCA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
PTPRN PDIA6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27880917 27432908
MTR1A GRP78 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17215244 26514267
PRKN2 PDIA6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32929329 25959826 24244333
PDIA6 TRXR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PDIA6 HNRLL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PDIA6 KLH24 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PDIA6 PLSI â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PDIA6 BTBD9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
CFTR UBE3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19233847 17110338
ESR2 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18765668 11500849
ESR1 SART3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 23403292 31527615
ESR1 PDIA6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 31527615
ESR2 UBE3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33456993 25408199 17962381
PDIA6 JMJD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PDIA6 VWA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PDIA6 ZHX3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CASP8 CUL3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PARK2 PARK7 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DNJC3 GRP78 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26085089 33957083
ESR1 PA2G4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 MED4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PPIB SGTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
CFTR GRP78 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 22038833 17110338
MTR1A PDIA6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17215244 26514267
TRAF6 CASP8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16436380 27810922 16920630 30979779
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
PRKN2 DNM1L â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21292769 30629163
CUL3 PDIA6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26949739 21145461
ESR1 DNM1L â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 19805454
CUL1 FBXO7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CUL3 KLH24 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 33130828 21145461
ESR2 MED20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11867769 29509190
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EIF2AK3 HSPA5 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PDIA6 PRDX4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PRKN2 CUL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12628165 24793136
CFTR GRN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26618866 29924966 17110338 31324722
MED20 MED4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 25281560 26344197
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AGR2 SGTB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
ESR1 MED20 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
H2AX OTUB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
ERN1 GRP78 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12637535 26551274 27238082 21118962 32149426
GRP78 PDIA6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24189400 22939629 33957083 30021884
HSPA5 ATF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18624755 31226023
CUL3 CAND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21145461 21249194 22013077 16449638 22405651 26286618 12609982
LRRK2 DNM1L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24282027 22228096 22639965 23813973 29541021
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
ESR1 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23167795 16423895 19366879
ESR1 LGALS8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
LGALS9 FYN â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 16286920 22505239 27192565
PRDX4 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
ERN1 HSPA5 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
PRKAB1 PRKAG2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GET3 APP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20676083 27193484 21743475 21636303 28104892 23129660 25179605
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
ATF6 HSP90B1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17991856 18360008 23850759 26587781
ATF6 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19667116 22189555 10856300 19622751 20165829 10866666 17117415 12076252 14973138 15899857 17241871 20801537 11256944 16452489 17522056 10564271 12713871
FYN BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17129785 9188452 9020138 10739664 31413325 16713569 11181827 9360983 17474147
COL1A1 P4HB â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
HSPA5 EIF2AK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17145710 28534368 18624755 11907036 31226023
HSPA5 ERN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18624755 26551274 31226023 12637535
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
FN1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
FYN SH3KBP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 17350651 23052211 23506116 16529723