PKG

Protein list:

HDAC5 SLC2A4 H4C6 SMAD4 GRK2 H3C14 SMAD3 H2AC20 CABIN1 H2BC21 PRKCA PRKACA AURKB TLK2 PRKAA1 PRKCD DYRK1B CAMK2G CAMK1 RUNX2 CAMK4 PRKD1 IKZF1 PCBP2 HIST1H3A DDX17 ACTN4 NOP2 AHRR SF3B1 HOXC11 SLC25A11 SFXN1 SLC16A11 SHMT2 SF3A1 LARS USP9X SF3B3 NUDC ETFA RUNX3 UBE2I YWHAQ ADAR CCT2 FXR1 EIF4A3 ALDH18A1 GLUD1 ELL DDB1 CBX5 MAFF DARS EEF1G LDHA YWHAH APLP2 DDX1 BRMS1 IMPDH2 CAMK2A DDX20 BAG2 CANX ECH1 NRIP1 ESR1 GCN1L1 PSMD11 CCT4 CUL7 DHX15 CCAR2 DNAJA1 CSNK2A1 EIF3L FASN ACAT1 DDOST CDK1 DHX9 ESRRA HADHA EIF3F HDAC4 CDC5L HDAC1 DDIT3 CTBP1 ACLY H3F3A ALDOA AHCY GNB2 GATA1 CCT8 CIITA CAD GATA2 GCM1 ATF3 YWHAG CSE1L DNAJB11 FLNA ANKRA2 GOT2 COPB1 EPRS HCFC1 BCORL1 CCT5 ATP1A1 RPL4 SIN3A RBBP7 SRSF1 RPL10A HSD17B10 PPP2R1A PHGDH XRCC5 C1QBP CCT6A ATP2A2 BCL6 CCT7 YWHAB MARK3 CKMT1B NUP214 CAND1 HNRNPH2 ILF2 EIF3B SMC1A PPIA MCM6 HNRNPA3 SF3B2 DDX47 REST OAT IKZF2 USP7 PSMD2 PARP1 TFEB SLC25A6 SLC25A1 VDAC2 HSP90AB1 JDP2 TFE3 PSMB5 DDX3X RPS3A SUV39H1 SIK3 SMC3 XPOT IKZF4 PRPF8 SMAD7 PKN1 PPP2R2A PRMT5 TFRC RL2 RUVBL1 IKZF3 RFXANK EIF4A1 GNB1 ZBTB16 PSMC5 HNRNPD RARS RPL5 CS IRS4 PCNA PKM SIK2 HSPD1 VDAC1 PRPF19 RAN HIST2H2AC TUFM HSPA9 MCM4 RPN2 XPO1 RAD50 MDH2 SFPQ TP53 TUBB4B ATP5B MAP1B HSP90AA1 NFKBIE TOP1 RPL9 ZBTB7B RBM25 YY1 RPL7A PRKD2 SLC2A4RG RBMX SNRNP200 MAX UPF1 EFTUD2 CLTC NFS1 GATA3 MYEF2 MCM3 RBM14 CCT3 DDX39B PA2G4 TKT RPS3 WDR5 HSPA4 HSPA1A HSP90B1 TRIM28 NUP93 NONO RBM39 NPM1 TUBA1A RPSA KLF4 PRKD3 TPI1 PRDX6 PSMC6

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1

Function:

Eg: Homologous recombination

Path:

Eg: SMC5 > DMC1 | PBRM1 > BRCA2

Relationship:

Full list of relationships

Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

PKG Score Threshold: 0.8

Layout:
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Filter Table:

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Source	Target	Relationship Type	Directed	Sign	DB Score	PKG Score	Database	References
ACTN4	ESR1	◼ PHYSICAL_INTERACTION			0.85	0.85	HIPPIE	25604459 19805454 21078666
ANKRA2	HDAC4	◼ PHYSICAL_INTERACTION			937.0	0.93	STRING	36370105
ATF3	TP53	◼ PHYSICAL_INTERACTION			835.0	0.83	STRING	36370105
ATF3	DDIT3	◼ PHYSICAL_INTERACTION			875.0	0.87	STRING	36370105
ATF3	SMAD3	◼ PHYSICAL_INTERACTION			0.89	0.89	HIPPIE	20930144 12718878 16189514
ATF3	DDIT3	◼ TRANSCRIPTIONAL_REGULATION	✅	+	5.0	1.0	Omnipath	9343434 14729979 22753726 10085237
AURKB	HDAC4	◼ POST_TRANSLATIONAL_REGULATION	✅	-	3.0	0.9	Omnipath	22865920
AURKB	YY1	◼ POST_TRANSLATIONAL_REGULATION	✅	+	4.0	1.0	Omnipath	23226345
AURKB	TP53	◼ POST_TRANSLATIONAL_REGULATION	✅	-	13.0	1.0	Omnipath	20959462 27933271 20847049 15469940 32873634 22611192 27496712
AURKB	HDAC5	◼ POST_TRANSLATIONAL_REGULATION	✅	-	4.0	1.0	Omnipath	22865920

Showing 1 to 10 of 786 entries