Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZNF804A ANKRD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23434502
ZNF804A DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23434502
ERO1A PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
DDIT3 ERO1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19359519
GIT1 TRIB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ATF4 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16931790
MYC CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21925595 23722468
JUND CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11973337 14686613
JUN JUND â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8922393 2504580
JUND IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23398888 14686613
JUND MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12226747 21734453
TP53 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16227626 9806359
CEBPG PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16227626 15778982
PRL ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25193864 19524120
H3-3B DNMT3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19834512 7297014
H3-3B KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
KAT2B H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 34811519 15616580
CEBPB ADIPOQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15919796 15850785
ATF3 ADIPOQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16644691 19932681
DDIT3 ADIPOQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17395745 17395738
PPARA ADIPOQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12829629 17194889
TP53 ATF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
ATF2 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11413310 12388374
ATF2 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20086235 10037779
ATF2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11243868 19948881
ATF2 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17189429 17700520
ATF2 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17079470 17258390
ATF2 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17700520
ATF2 MMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17079470
ATF2 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20102225 23661758
TP53 ATF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ATF3 ATF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23850759 26587781
ATF3 ATF4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 23850759 26587781
NFE2L2 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24509533 19864258
CEBPB ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16989641
NFKB1 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24100018
ATF3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22046379 18644986
ATF3 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20565867 21467165
ATF3 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24951825 19097984
ATF3 PPP1R15A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22033410 14729979
ATF3 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24420912 26554515
DDIT3 ATF3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
ATF4 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20617572 19648113
ATF4 FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18471544
ATF6 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21821716 18450959
ATF6 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9837962
MAPK8 ATF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25301550 26538579
JPH3 BAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BBC3 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22492984 17289999
BATF JUNB â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
BATF3 JUNB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
JUN BATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12087103
FOS BATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12087103
DDIT3 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15836916 20398749
CEBPG BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16254192 12970736
BCL2 MAPK8 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15733859 5217553
NFKB1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704864 11313951
JUNB BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11163237
DDIT3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17652152
FUS BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18471544
FLI1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11847117
BCL2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15210690
TP53 BCL2L11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19427386 20124456
MYC BCL2L11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16169462 21899728
DDIT3 BCL2L11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22347430 22761832
MYC BCL2L11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12209154
FUS BCL2L11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18471544
TP53 BDKRB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15632413 10748162
TP53 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
HDAC3 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
CEBPD BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16720721 11668178
YY1 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8990171 10804019
ID1 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8045940 18287524
CEBPG BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15713650 11668178
KPNA2 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9497340 6547667
FOSL2 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23339184 17434164
YY1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21666725
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
BRCA1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 12700228
FOXO3 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20211690 19807657
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
CASP3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9500443
CEBPD CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12145301 15829559
ESR1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20404154 17932106
DDIT3 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18649942 15829559
FLI1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25108845 23108091
ESR1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12603855 26790618
RELA CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18504428
RB1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671466 14527674
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
SMARCA4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
PPARG CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15041706
CEBPA MYC â—¼   DOWN_REGULATES ✅ - 2.0 0.8 ACSN 11340171 20581311
HDAC1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16431920
CEBPA ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22568493
CEBPA FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1320003
CEBPA HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2247079
CEBPB KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23456364 17301242
CEBPB MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9743233 22139077
CEBPB FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7543095 11473033
CEBPB NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21150337 9019155
CEBPB RETN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19126543 20506172
CEBPB GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16418324 11012671
CEBPB HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23251594 22905241
MAX CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20426839 17471507
JDP2 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21197464 17464331
ZBTB17 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20426839 17471507
JUN CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17965828 20506344
CEBPD LCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22514649 20220144
CEBPE MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12947005
CEBPG FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11473033 8567694
CEBPG PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10862621 12524424
CEBPG GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15860545 12970402
CEBPG CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7491114 7629103
CEBPG FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15860545 10531366
CEBPG HAMP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21289291 12183449
CEBPG MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10506168 19939245
CREB3 RPS3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CREB3 SLC29A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CREB3L1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15572842 15665855
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
HSPA5 CRP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DDIT3 CRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17513780 15277326
MYC CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1508191 17512931
YY1 CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8264581 8114709
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
NFKB1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19027835
CSNK2A1 RELA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5212888 10938077
NFE2L2 CUL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21793854 20452971
JUN CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19299558 23250032
HLF DBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9571207
SPOP DDIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FOSL2 DDIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
MCMBP DDIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HSD17B14 DDIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
JPH3 DDIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GFAP DDIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DDIT3 HSD17B14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NFE2L2 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22691366 14978030
DDIT3 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10912181 10510472
DDIT3 LCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22800509 21741997
DDIT3 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18794136 19074988
DDIT3 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19029092 19164449
FOS DDIT3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PRKAA1 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 27650555
DDIT3 ITGAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19359519
TP53 EIF2AK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19416861 10082513
G3BP1 EIF2AK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25784705 25520508
EIF4E G3BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 6665011 18005740
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 RELA â—¼   ACETYLATION ✅ 2.0 0.8 intact 5214468 11533489
EP300 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11896584
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
HLF EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9113979 10202154
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
ESR1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18313050 19861308
ESR1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9259323 8625613
ESR1 SLC38A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056967 18414489
ESR1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 18511507
ESR1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19797124 20819530
ESR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16144913
ESR1 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11477071
ESR1 MAPK12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16885352 22399296
ESR1 LCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 21741997
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16144913
ESR1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24641954 20623181
RELA F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11463837 19351910
FOS FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10903433
PPARG FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20416398 15644454
TP53 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9841917
YY1 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18495079
FLI1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592502 20153576
PPARG FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12921977 17320065
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
RB1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1909121 7680889
PPARA FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17360982 18754816
FOS MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10348347 12173040
FOS INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9270011 12516092
FOS NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20188076
FOS HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11719466 10472808
FOS VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12163680 11353786
FOS RELA â—¼   PROXIMITY 2.0 0.8 intact 18172215 0705181105
MAPK14 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18253836
RELA FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10488148
FOXO3 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17132628 16100571
FOXO3 ID1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17132628
GABBR2 GABBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218685 16724110
SMARCA4 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
JPH3 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AB1 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9038169 9151685
GFAP LNX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23940366 9360971
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PPARG HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21151932 16431920
HDAC3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16847267 0510834103
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
HDAC6 HSP90B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19158084
MYC HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17881904 18544564
RELA HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18421578 15964798
HOXA5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19918835
HSP90AB1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
HSP90AB1 KEAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20864537 26517842
XBP1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17612505 15270080
PPARG HSPA1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19116451 15315910
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA5 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NFYA HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22530004
ID1 ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9779825 19896442
PPIB ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16557594
RPS3 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS3A IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC IKBKG â—¼   COLOCALIZATION 2.0 0.8 intact 20970423 8045055
NFKB1 IL15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21343618 10906187
NFE2L2 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27211851 16339837
NFE2L2 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21127061 27211851
MYC INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799123 1917937
JUNB INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9062890 18716665
TP53 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12392301 22242153
JDP2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11287607 25026555
JPH3 LNX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JPH3 PPARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
JUN MAPK8 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
RELA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17310108 10646503
JUN PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16729332 20143420
JUN PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17138645
JUN PPM1D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20093361
NFKB1 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17018379
NFE2L2 KEAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19560419 23850759
NFE2L2 KEAP1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19560419 23850759
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
PPM1D MAPK12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15870257
MAPK14 RB1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17380128 5219804
MAPK14 PPP1R15A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11163539
MAX TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7969121 10348347
RB1 MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218170 16374512
MDM2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 23839035
MLXIPL PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16936198 21282101
TP53 MMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
MYC NFYA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11282029
PPARG MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16838108 11477074
MYOD1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16527841 19553684
MYOD1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18094043
MYOD1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 17043109
RB1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21902831 8381715
NFE2L2 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17313370 16923960
NFE2L2 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22911891 16172382
TP53 PI3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15928193 20020498
TP53 PKD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20388565 16931520
PPARA PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17275789 22033933
PPARA TRIB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20461355 16949670
RELA PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10542237 16189514
PPARG PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18309368
TP53 PRKAA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RPS3 RELA â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24457201
RELA TRIB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12736262
RPS3A TXN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPS3A XBP1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 SLC38A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
TP53 TNFRSF10B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11498783
BACH1 MAFG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ATF2 JUND â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ATF4 CREBBP â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
FOXO3 TP53 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
JUN ATF3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 10327051 6546308
MDM2 ATF3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 34114479 31796886 20592017 15933712 29225035
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22013068 12960163 14662860 12471036 23811396 11739381 20065107
JUNB EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21937452 15308641 17510411
RELA RPS3 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
HSP90AB1 HSPA1A â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
BATF3 LDOCL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DDIT3 LDOCL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 20562859
JUNB CN080 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOSB ATF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32296183
EP300 ATF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24069158 10327051
CEBPB ATF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20110283 20102225
CEBPD ATF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29601799 20102225
ATF4 CEBPB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11018027 20102225
DDIT3 ATF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 20102225
CEBPG ATF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 20102225
BATF3 ATF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BATF3 BACH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BRCA1 FUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
PCM1 DDIT3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27107012
DDIT3 SPOP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16189514 24990631
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
FOS ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
ESR1 FAS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
HDAC6 G3BP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32082291 18079183 21532619
JUN HDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 17056544
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
NFYA KAT2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16959611 15647279
CREBBP FOXO3 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
PDIA3 ERO1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20802462 17170699
MAFF GIT1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDK9 CUL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11689688 12861003
JUN JUND â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649
BATF JUND â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 8570175 20102225
MAFF LDOCL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DDIT3 ATF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
ATF2 FOSL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23661758
FOSL1 ATF4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 1827203 23661758
ATF4 CEBPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
DDIT3 BACH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
BATF CEBPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
BATF3 HLF â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
BATF3 CEBPG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
NFYA BRCA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11777930 16713569
BRCA1 CDK9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22990118 28278048
CEBPA CEBPG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
CEBPG JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23661758
CEBPG FOS â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
DBP DDIT3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21988832 23661758
DDIT3 JUNB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
DDIT3 FOSL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27107012 32296183 20102225 25416956 16189514
ESR1 JUNB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 11477071
NFYA JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11903046 21565167
ATF3 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CSNK2A1 HDAC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATF2 BATF3 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ATF3 MDM2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ATF4 FOS â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
KAT2B MDM2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CDK9 TP53 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
MAPK14 RB1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ATF3 CEBPG â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20211142 16189514 23661758 20102225
ATF3 ATF7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30833792 20102225
JUNB ATF4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21988832 23661758
ATF4 BATF â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
HLF BATF â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
CEBPG BATF â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
DDIT3 CREB3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
CSN2 JUN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16045761 10903862 25609649
DDIT3 HLF â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
DDIT3 NFIL3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
FOXO3 EP300 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25609649 11896584 19592618
FOXO3 MDM2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
MDM2 PPIB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24583282 29876924
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
BATF3 JUN â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
BAK1 TP53 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CDK9 RB1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
FOSL1 JUNB â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CDKN1A EP300 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ATF2 MAPK11 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
BATF3 ATF3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12805554 20211142 23661758 20102225
MDM2 ATF4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27264869 21988832
CASP9 CASP3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 1067155 11242052 11230124 18723680 25241761 15941357 17437405 8900201 15507451
CEBPE CEBPG â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15588942 23661758
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
XBP1 FOS â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 1903538 16189514
MYC HDAC3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18483244 31155734 22002311 23079660
MAPK8 JUN â—¼   PHOSPHORYLATION ✅ 0.85 0.85 mint 7148309 19527717
ATF7 JUN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CEBPB EP300 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
RPS3 RPS3A â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
BATF DDIT3 â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
MDM2 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24804778 20708156
HLF DBP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23661758 21988832 10073576
ESR1 DNM1L â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 19805454
HDAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16469706 26487511 14722073 31527615 20348541
ID2 MYOD1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9242638 21209940
ATF2 JUNB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CREBBP MDM2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CDKN1A GADD45A â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ESR1 FOXO3 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
ATF4 NFE2L2 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
IKBKG RELA â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 15489227
JDP2 JUND â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9154808 18671972
BATF3 JUND â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 20102225
JUND ATF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 20102225
DDIT3 CN080 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 18330356 20562859
JUNB ATF7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 20102225
BACH1 ATF7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 20102225
FOSL2 ATF7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26496610 26186194 20102225 28514442
FOSL2 BACH2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 32296183
BATF2 JUNB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21988832 23661758
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MYC CDK6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22094256 28205554 28628118
CEBPB CEBPD â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 1840554 20102225
CEBPE DDIT3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15588942 20211142 23661758
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
JUN FOSL2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 25609649
G3BP2 G3BP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26777405 24981860 29395067 26186194 28514442
KEAP1 MCMBP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 25036637 32296183 27621311
OFD1 PCM1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24089205 26496610 26638075 34079125
BRCA1 CREBBP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDK6 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 16508017
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
G3BP1 G3BP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
FOSB JUND â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ATF7 FOSL2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BACH2 MAFG â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
BACH2 BATF3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BBC3 BCL2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSPA4 PARK2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ATF7 FOS â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PTGS2 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATF3 DDIT3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CASP3 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DDIT3 FOS â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HDAC3 RELA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RB1 SMARCA4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ATF2 JDP2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EP300 PPARG â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MAPK14 TP53 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
JUNB JUND â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
RS3A DDIT3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 10713066
ATF3 ATF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20211142 23661758 20102225
CEBPG ATF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 12805554 23661758 20102225
ATF2 BACH1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23661758 20102225
FOS ATF4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25241761 23661758 20102225 1827203 16189514
DDIT3 ATF4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12805554 23661758 20102225 18330356 16189514
DDIT3 BATF â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27107012 23661758 20102225 18330356 16189514
BATF2 JUN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19074269 23661758
DDIT3 BATF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32296183 20211142 23661758 20102225 25416956
MYC CDK9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17700062 12944920 30415952 26687678 19818711 11673469
CEBPB CEBPA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 1840554 15751966 20102225
CEBPB CEBPG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20102225 12177065
CSN2 CUL3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26976604 21145461 32047038 16045761 28514442 19295130
FUS EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33742100 30110629 18509338
EP300 PPARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18797151 9407140 10336495
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HDAC5 HDAC3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11931768 11804585 21081666 11466315 10869435 10220385
ESR1 HSPA4 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HDAC3 YY1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ID1 MYOD1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MDM2 RB1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 MYOD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MYC ZBTB17 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
BATF JUNB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
BCL2 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MAPK8 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CREBBP KAT2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREBBP JUN â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
KAT2B MYOD1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MAFG NFE2L2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
CUL1 CSN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26976604 19141280 29103612 21145461 32047038 11967155 16045761 16036220
FOSL1 JUND â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26258633 24029232
JUND BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12080089 16713569
PRL PPIB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10935542 16713569
FOSL2 ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 26186194 20102225 28514442
JUNB ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 16511568 20102225
BATF3 ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 23661758 20102225
JUN ATF7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 26496610 20102225
BATF3 BACH2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 32296183 23661758
HDAC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 21102443 16713569
CEBPA DDIT3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27555288 33961781 23661758 20102225
DDIT3 CEBPG â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20211142 23661758 20102225 25416956 16189514 12618752
JUN DDIT3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23661758 10523647
KAT2B EP300 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12888487 22384255 9267036 12419806 21413932 20870727 33051058 8684459
MDM2 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897156 17545634 10766163 11178989 16713569 31012223
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
JUN MYOD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 1310896 16713569 8380166
BAK1 BCL2L11 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ATF2 FOS â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CREBBP RELA â—¼   ACETYLATION ✅ + 0.89 0.89 Signor 16382138
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MAFF NFE2L2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
ATF4 TRIB3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FOS JUND â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
FOS JUNB â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CEBPG ADH1C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14667815 2050667 1654768
DDIT3 GIT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18940792
PPARA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16220077 15120605 10988245
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
MAPK14 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278789 10806218 12917630
CEBPG ADIPOQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10598019 15850785 15504955
CEBPB ASNS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15385533 18840095
FOS ATF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 1828107 32296183 25416956 16511568 23661758 25609649 20102225 26186194 20195357 1827203
ATF2 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18638549 15618023
ATF2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23800081 10506225
ATF2 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23443926 19491401 15767263
ATF2 IL23A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22904313 18802055 19592489
ATF4 ATF3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20102225 19164757 23661758 16189514
ATF3 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10760799
NFE2L2 ATF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21087962 23618921 20185790
ATF4 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16026328
ATF4 EIF2AK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23009153 21146245 17141186
ATF4 TNFRSF10B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21044953 24939851
ATF4 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12057991 21244365
ATF6 XBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24269637 20003459 12949534
HSPA5 ATF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18624755 31226023
TP53 ATF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
MYC ATF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
BRCA1 BACH1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15125843 17525340 17664283 19369211 16391231 11877378 25252691 11301010 15242590 16713569 15208681
BACH1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19897490 15734732
TP53 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 15077116
BCL2L11 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22492984 12242151
DDIT3 BBC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20430872 21159964 22761832
JUN BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14623928 17262823 19335069
CEBPB BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12970736 19717648 17043638
ZBTB17 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21167753 19549844 17082179
MAPK14 BCL2L11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15486195 17570479 16818494
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
JUNB BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 18259752 16713569 28514442 25184681 12080089
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
JUN BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25609649 12080089 16713569
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CASP3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12149654
BRCA1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15520196
CEBPB CALCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19261615 18650268 22905241
NFE2L2 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10510468
MYC CASP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PPARG CCL2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 10432118 17681149 23390297
TP53 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22804246 23666675 20406462
PPARG CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12909507 20663893 11932328
CDK6 CDKN1A â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HSP90AB1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
CDKN1A RAI1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CEBPG CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10982390 9442037 15041706
CEBPD CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10373535 7910803 10623469
CEBPA GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11914124 11579200 8702932
MYC CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
CEBPA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
EP300 CEBPB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9343424 14630807 12471036 28428115
CEBPB XBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19717648 19490910
CEBPB TRIB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21203563 19164449 16949670
CEBPB CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11726661 14976147 11158330
CEBPB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21098707 20581311 16585579
MYC CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21143913 20426839 17471507
CEBPE CEBPG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15588942 23661758
CEBPG INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2404278 9668047 8817653
CEBPG DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15781252 12082616 12069855
CEBPG CRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10880233 18684932 17335903
YY1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9238849 21852380
NFE2L2 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17313370 18241676 18199529
HDAC3 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16528103 18241676
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
SPOP CUL3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25278611 22632832 16524876 21577200 19256485 29160310 28216678 22013077 21988832 25011449 30244836 19261606 31559706 22911784
KEAP1 CUL3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15367669 28186440 15572695 20864537 25742418 33130828 20534351 20027226 30765703 32854194 23727018 25628777 26757824 17439941 16449638 16790436 21357422 19818716 32341456 20421418 22245129 26219975 22558124 32296183 24896564 15983046 30383469 18251510 24127568 22911784 33391509 15282312 20865015 24322982 21145461 20599909 17822677 22448038 18417180 30273379 15601839
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
FOS DDIT3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32814053 23661758 10523647 26264872 20102225 16189514 29997244 31467278
MAX DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15021909
XBP1 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16757577 17455323
FOXO3 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18226221
JUN DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19299913 22622069 12069855
DDIT3 SLC38A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18940792
DDIT3 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18940792
DDIT3 FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10523647 16189514
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 KPNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10801418 15342649
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
NFKB1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22223884 10649441 10867646
PPARG FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10678274 23657115 18059282
RELA FOSB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20018891
FOSL2 FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 13679379
MYC FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
FOSL1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20353950 19289495 18288638
FOSL1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19687301 20386569 11028561
FOSL2 JUN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
FOSL2 JUNB â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
FOXO3 PRKAA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24257750 22848740 17711846
GADD45A TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GADD45A RAI1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAX GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15021909
TP53 HAMP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17593032
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
HDAC3 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12150997 15811852 15494311
TP53 HSPA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
HSPA1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
ID1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17426247 17145808 23657791
IKBKG RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15489227
NFIL3 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8547328
JDP2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18671972 9154808
JUNB PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9620167
MYC KAT2B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 12660246 15572685
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RELA MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 MAPK14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11437382 15132979 14570892
PRKAA1 MLXIPL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11724780 21892142
NFKB1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19303700 20352621 17498959
RELA MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19303700 20352621 17498959
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
MYC NFIL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC PI3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
RELA PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20054868 10542237
PPARGC1A PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21775429 10669761
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
PRKAA1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19217427
RELA PTX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18226221
FOSL2 JUND â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
FOSL1 JUN â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CDK6 RB1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
KAT2B TP53 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
HDAC3 HDAC5 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ATF2 MAPK8 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
TP53 JUND â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
EP300 RELA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATF3 JUN â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CREBBP RELA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ATF4 CEBPG â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
JUNB FOS â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218398 16511568
PPARA PPARGC1A â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
JUNB FOSB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 28514442 32296183 12371906
JUN JUNB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 25609649 28514442 33961781
NFE2L2 MAFG â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 34591642
ATF2 MAPK14 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
JUN FOSB â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 25609649 29020630 33961781
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
ATF3 JUND â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 8152431 30833792 20102225
JDP2 ATF2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 20211142 11231009 18396163 18671972 18307971
TRIB3 ATF4 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 20211142 32296183 12743605 25910212 18276110 25416956
JUNB FOSL1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 32296183 23661758 24029232 16189514 12371906
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
JUNB BATF â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6785080 18692475
JUN FOSL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11912197 33961781 11431474 11708771 23661758 9160889 24029232 20511396 26258633
CREBBP PPARG â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
FLT1 VEGFA â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
COPS7A COPS8 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
JUND FOS â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 12193410 35140242 11431474 20195357 26496610 25609649 20102225 26186194 24029232 15867431 28514442
GABBR1 GABBR2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
PPARG PPARGC1A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS3A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
KEAP1 NFE2L2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS3 COPS7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS3 COPS8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL3 SPOP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
JUN MAPK8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MAX MYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ATF6 ERO1A â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17991856 18360008 23850759 26587781
RELA CXCL8 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15079071 15536066 17550372 19171876 23430059 8383323 9743347
RELA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 129.0 1.0 Omnipath 12820969 24337575 15289496 9405619 9698090 20038977 15057743 21665565 24260304 10817569 14631383 10969814 15005855 19668231 16325549 19732956 8207232 18281166 27856305 23894194 9388261 26340924 10975857 10745031 20194077 10928981 16553947 17565687 16764699 22848596 15531761 16105834 16803583 9510190 15355994 18221537 12643600 20053934 11716760 8617886 12218154 12707271 23637609 27076634 8878392 17917246 12163591 16829531 16818736 14670967 12038622 15958549 18362169 8413215 19734226 23386688 11297551 15950427 17362989 16455661 27371733 11953364 8413306 18074095 11973337 18786178 19376732 19837667 17276517 15517885 11342414 18669446 7876168 15350531 14645117 22891766 18034886 11564889 12748173 17586662 18996370 15223809 17041011 12485925 16004996 15079071 21343296 26618242 18435575 17636245 22340043 19173296 24634218 11120852 10477716 21343177 12058956 17045242 19786024 24048734 24770886 10202011 18309103 11864912 21131967 19064995 10530453 12716652 16418726 28283022 18723827 17040605 21255844 15615716 17932106 19966855 20696864 15387324 21451502 15722553 15879558 12855659 12883201 15688424 18045535 10506755
PPARG CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19395102 18485432 20107546 20554962 16303327 20889551 15331599 12695526 15720834
JUN CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 18684922 16701870 24048734 14686613 24284797 15057743 12643600 17197543 11864912 10817569 12218154 22031759 17586662 10969814 19064995 12716652 27856305 25582859 17471497 22095787 16818736 23176534 14670967 18435575 16846747 19734226 16299055 14612204 18772138 19132242 12209633 15939312 16834785 11399048 11120852 25567680
DDIT3 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18772138 22031759 17709599 15688424 21471847 18850010 17197543 15659384
NFKB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 9510190 12058956 11973337 18786178 17045242 15289496 16701870 19376732 19837667 9698090 17276517 11512674 19786024 20038977 10202011 15057743 15517885 12643600 11342414 7876168 15350531 18034886 11716760 11564889 11864912 12218154 12707271 10969814 12748173 14631383 16325549 17586662 18996370 19732956 17041011 10530453 18281166 12716652 16418726 12485925 16004996 9388261 8878392 17917246 10975857 10745031 10928981 16553947 16818736 14670967 18435575 12038622 15958549 17040605 8413215 21255844 22340043 1401924 9452482 16764699 11297551 15950427 15387324 15879558 16105834 11953364 15688424 18074095 8413306 11096450 16803583 10506755 11120852 10477716
CEBPG CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12177065 8530498 15223809 8413306 20388952 8207232 9271387 18824136 18199703 18850010 19734226 8999951 12561382
ESR1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15208657 16029657 19440537 14991571 18669446 17932106
FOS CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11973337 18317936 12218154 22095787 12748173 10969814 15005855 17586662 16818736 24048734 14686613 16846747 15057743 15615716 8999951 25567680 19173296
CEBPA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22685373 25119735 8999951 18199703
CEBPB CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 23051921 10775602 17135982 8969274 17997161 18512730 21471847 24554449 14645117 15085176 17845418 12707271 12748173 19489038 22031759 8234276 19064995 8207232 16989899 27856305 11991987 19109189 17471497 19786303 16809637 16818736 21255844 19734226 24038085 18772138 19805069 20861254 18487355 11390611 15688424 10462040 16803583 8999951 11120852
RELA CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
NFKB1 CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
ESR1 JUND â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 25542856 18219272 3677090 20219941 23145106 1630819 3045126 15514030 24854081 22265404 17013392 21835891 9671459 21940756
JUND FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23319049 13679379
JUND GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17084916 21734453
JUND CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10760799 19828633
JUND IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10037779 11337499 11886848 12727841 24676671
DDIT3 JUND â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10523647 11426938
MAPK8 JUND â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16007120 22327296 14676207 12052834 26538579
CEBPB PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10455153 15479564 10649437 24248464 16227626
ESR1 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 3481434 9259323 7649480 18022314 2082192 10830306
MAPK8 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
PPARG ADIPOQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 19843873 20668453 19324019 19833717 20473515 12829629 15764598 18804108 19954946 11533050 16803864 20622112 18296319 18373719 12927809 20484463 23381555
PPARG ADIPOQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12829629 20592862
ATF4 ASNS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18840095 18940792 17276738 23403946 16164412 15385533 11960987
DDIT3 ASNS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22955275 18940792 16164412
ATF3 ASNS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12881527 15385533 18840095
ATF2 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10909971 17337306 21278380
ATF2 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12833146 8576171 20581861 10979959 18719024
ATF2 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11901151 17591797 11278336 12057991 16007171
ATF2 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21479385 8335091 10471826 8703044 9151819
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
MAPK8 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 11279118 17081983 20506250 12958075 9162092 19255142 8654373 20028971 15105425 17626013 12788955 11566021 15550563 10777545 23331499 7535770 15068801 21071413 17875713 9317150 16393692 15304344 18988627 7737130 26538579 21444723 602896 11896587 12110590 7824938 11274345 12874243 11971971 9399639 19436832 16533805 9670022 9029150 11865055 9207092 12804775 7737129 15212693 9405416
MAPK14 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 17081983 18767875 21098032 20506250 26359454 19690332 11060298 19413330 12788955 10085140 22037767 11566021 17079470 19647037 10581204 10777545 7535770 23331499 7839144 19324872 21071413 21614932 20068231 16393692 15304344 17570479 17380123 18988627 7737130 18669648 15187187 9305639 7737129 15140942 602896 11896587 17548358 12110590 7824938 8663524 33893075 12024021 11078583 11971971 9707433 17258390 10821277 19651622 19436832 11259586 27726305 11781825 9430721 27142525 10909971 12118074 15569672 15212693 9753474 11274345 10903740 26987986
JDP2 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18396163 18307971 18671972 11231009
MAPK13 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 9207191 10581204 15140942 20506250 21614932 19135240 16393692 12244047 11274345
MAPK11 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 17145710 17081983 20506250 19690332 19413330 17079470 11566021 10085140 17254968 10777545 7535770 7839144 21614932 16393692 15304344 17380123 7737130 15192015 18669648 15187187 15140942 9235954 12110590 17258390 19436832 9155018 9430721 9029150 14734562 11274345
RB1 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1641004 11566021
MAPK12 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 15140942 20506250 9029150 21614932 11238375 16393692 10085140 11274345
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
ATF2 ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12833146 20211142 20102225 23661758
ATF3 ID1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16713975 16831886 17490644 18832382 21614932 23850759 9389648
TP53 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12386811 12372430 17108111 21927023 21394211
ATF4 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10085237 16246168 21801305 17042743 22819556 23269699 25681212 16989641
JUN ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8576171 21304988 14667575 10979959 22870894
ATF3 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9343434 14729979 22753726 10085237
ATF3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20203264 24317040 17785797 24951825 20351107 22105779 16688168 18942706 17766920
TP53 ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15933712 18431400 11792711 16169070 16713569
JUN ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10327051 25609649 1827203 14667575 20102225 23661758 8622660 20304822 8649793
ATF3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10327051 25609649 1827203 14667575 20102225 23661758 8622660 20304822 8649793
MYC ATF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333 23612979
ATF4 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16006626 12082616 10085237 15775988 12083523 16246168 18940792 20020050 17276738 20732869 21044953 22802018 17726049 21966512 17455323 22691366 31226023 24939851
ATF4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18829529 20824063 14747470 15788408 20221394 24347168 23908598 18172307 18617696 23649506 22915762 18451308
ATF4 TRIB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20592469 15775988 18940792 21068199 15781252 18408768 21220698
ATF4 PPP1R15A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19564919 23907468 12840028 31226023
ATF4 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11564156 9295363 25241761
ATF4 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12805554 20102225 18330356 23661758 16189514
ATF6 HSP90B1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17991856 18360008 23850759 26587781
ATF6 XBP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17991856 18360008 23850759 26587781
ATF6 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 31226023 17455323
ATF6 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19667116 22189555 10856300 19622751 20165829 10866666 17117415 12076252 14973138 15899857 17241871 20801537 11256944 16452489 17522056 10564271 12713871
BCL2 BAK1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
DDIT3 BAK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17166886 23339468 16597647 14612528
TP53 BAK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22983126 18519674 21233848 15033822 15489892 15105295 10741712
BCL2 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 9463381 14980220 11206074 17289999 26004684 11728179 20836993 19168699
BCL2 BBC3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11463391 11463392 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
TP53 BBC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 23916609 14665630 18397889 17390010 22763818 11463391 15988033 16462759 17280505 22948151 16151013 20190809 23678107 17989286 17360476 11756653 20331637 21835778 15790310 17440969 20478995 17047080 12384701 18657356 18755897 15489892 18579560 11463392 11572983 15007388 17610896
MYC BBC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12695333 12384701 19815507 20145032 21835778
TP53 BBC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12574499 11463391 11463392 14634023 14684737
BBC3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17145710 16697956 15694340 11463392
BCL2 BCL2L11 â—¼   PHYSICAL_INTERACTION 12.0 1.0 ACSN 10198631 11704864 15486085 15724238 17446862 22039431 23064052 23377657 23430059 23850759 8929532 9430630
NFKB1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11313951 11704864 21725609 23178297 23572150
KEAP1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
CUL3 BCL2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
MYC BCL2 â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
TP53 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17693666 8183578 10037739 16738310 18397889 19521340 18487508 21666495 16294215 21656028 22869582 19714248 10744634 8174112 17592775 11782367 19137013 20428827 18682598 11713302 11313951 20501806 9649502 24814047 15767042 24098340 11193470 10329733 21859835 22266868 10953306 19555669 23638218 14684736 19411072 20530667 24155778 8205530 20840522 9000137 15326476
NFKB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 16254192 11567031 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 12032828 19233129 16022909 18761399 18987666 15934930 21224428 16453001
PPARG BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15067355 14960510 15878253 19956851 15094967
MYC BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8036017 17404573 12695333 24167291 18809243 19201832 16316993 19649202
RELA BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 19233129 16022909 18761399 18191642 21224428 16453001
ESR1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19148464 19160418 9306964 11261829 21841772 10542244 20664923 18414489
CEBPA BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16254192 18987666 23814099 15713621 12970736
MAPK14 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 29050237 16714293 19336399 11495898
CREBBP BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9829964 10753867 17565603 15337521 10454566
MAPK8 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 12421819 26609913 17097560 16738310 21726807 10567572 21993018 29950132 20919655 22848813 15225643 19029119 9738012 18570871 9115213 12039864 11323415 15733859 18471544 15703383 23329792 10677502
BCL2L11 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 17145710 9463381 16697956 9430630 17074758 17097560 19805519 18498746 26004684 14517273 10198631 21199865 20836993 26186194 15694340 17289999 17692808 11301022 23845444 21671007 9731710
TP53 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12667443 19555669 8205530 19007744 11313951
CASP3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10409669 9395403 20139069 11948397
FOXO3 BCL2L11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22349704 12913110 19623194 20231287 22914323 17618288 15674333 21164521 15688014 17626006 21654193 14527951 16373335 14981546 23257900 19690465
JUN BCL2L11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17702754 16153157 23285061 22869147 21439021
DDIT3 BCL2L11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17604722 18471544
FOXO3 BCL2L11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17604722 11495903 11301023 18644865 19494111 10783894 14684737 16288288 15688014 11050388 11094066 18281283 20673124 17646672 15509806 11994454 11154281
MAPK8 BCL2L11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15486195 14555991 18691976 22071694 12591950 15470142 18174237 18498746 12818176
JUN BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9257196 2124710 15831452 17308994
FOS BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9610372 10804019 2124710 8828501 1749528
CEBPB BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15713650 16772287 16720721 18843047 11668178
BRCA1 RB1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
BRCA1 RB1 â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
BRCA1 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17428466 11777930 10962562 18025037 18350249 12647291
BRCA1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9926942 11394910 10196224 18025037 21245169 16735508 12647291
BRCA1 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 12771027 9346961 10779360 11877377 10367887 19004803 21060331 12496474 19793801 15650754 10962562 21337561 9892649 10528224 15459660 20029420
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
MAPK14 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 14970175 33176141 29414778
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
CASP3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25241761 9660939 10022118 9799125
CASP3 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10822366 11420704 9092486
CASP3 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 9278461 21726810 24842904 9840926
FOS CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18024959 18443042 14752027 8063765 12667961 17424890 7602115 9558097 16206198 19404962
NFKB1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10644332 22189654 20038977 11512674 8630731 12488502 12540607 11716760 8617886 12218154 14631383 16325549 10744656 10530453 11006087 16040075 10987310 16206198 9388261 10614622 16818736 10636866 10469356 17507908 12647268 16764699 25108845 20200316 15950427 20579762 11949945
PPARA CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19039651 10988245 19132243 15891579 16600694 11751881
PPARG CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16155367 17255125 20663893 15659119 15531761 20473515 18226310 18060855 12110006 20508203 11606585 10930382 16105976
CEBPB CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17180354 10748205 20019816 12145301 16784777 17390372 18649942 20730378 19026986 15710476
RELA CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 24337575 10644332 22189654 18226221 20038977 8630731 12488502 19738286 22189669 14976218 19371341 12540607 24260304 11716760 21138578 8617886 12218154 14631383 20952659 17452470 16325549 10744656 15223809 10530453 11006087 16040075 16730843 23583295 24063814 27076634 10987310 16206198 9388261 10614622 18353872 16166627 16829531 16818736 10636866 20195282 10469356 17507908 12647268 12682245 21106671 24550391 16764699 17932106 25108845 20200316 15950427 24634218 9174597 23198981 11949945 9916692 17537731 22723832
JUN CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19162185 18024959 18443042 14752027 22674286 23583295 19299558 12667961 10918580 19371341 26554515
CEBPB CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11937564 11413310 12388374 16239564
RELA CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 12820969 11478739 17510282 19786024 12050170 21138578 12122011 19828633 18367595 22030901 18502824 16707500 10926836 11413310 20663893 22388040 15144466 9120310 12603855 26096887 11259372 21189258 12388374 15972972 11389171 25523420 18525004
NFKB1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12820969 11413310 11478739 12122011 17065335 17510282 11700023 15144466 19786024 16707500 21189258 12388374 15972972 9120310 11389171 12050170 11259372
JUN CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11413310 10760799 19828633 10075858 20862675 26096887 7513046
CDKN1A CDK6 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14517297 17092340 9106657 18710949 24515438 20843055
RB1 CDK6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
MYC CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20682794 22395148 12835716
CDK6 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 25121590 20102411 15964852 22375140 15232106 16713569 16508017 19440234
CDK6 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 43.0 1.0 Omnipath 10498883 9315635 17303408 11416152 15081408 16236519 19690332 16936279 11520855 16107892 19413330 15279786 16360038 9190208 14627988 7575488 24417566 8822197 10385618 9736735 9139732 7736585 19075565 29372101 18590585 27507850 22682621 20068082 9425340 25549286 18786381 17660363 15809340 27811360 10778858 9380698
CDK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24173284 9372954 11483158 9315650 19413330 19664995 23603988 24202322 11709713 16083285 1088347 16552184 10884347 24286312 10747897 17942552 16741955 17287340 92065884 12064478 10348343 14702041
CDK9 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8870681 12037672 8170997 9258347
RB1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
ID2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17639499 16557594 21900881 16428453 11706002
RELA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18954936 22305266 23037503 18269916
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
CEBPB CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10982390 15466360 15041706
FOS CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12705898 12087103 14755691 16141357 10891399 11789587 21864583
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
ID1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20388787 17639499 10728702 20191379 23342268 20484992 19217708 9315646 22564737 18092003
FOXO3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18312651 18005957 16908841 20671123 21249150
PPARG CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19551868 19103521 19208833 16985067 18509005 15041706 15345676 16091736
JUN CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11136975 12717415 21278055 10506225 19628677 12054510 18094076 10072388 18210215 10733944
EP300 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10362258 15509808 21858218 22000024 21245169
CEBPA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15466360 9442037 12502863 8846917
MYOD1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10373569 25211658 18211587 18521215 16351709 17959144 14749395
HDAC3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9618481 17550342 12545156 15155580 22796940 22370643 16533812 17508028
FOXO3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15084259 19380174 21708191 15084260 21613825 17940099 11154281
ZBTB17 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9618481 12545156 17550342 17828269 10454538 15155580 11283613 11283614
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
MAPK14 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23745637 12058028
MAPK8 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12730199 15964852 17325029 19664994 12058028 11779850 17570479 20519948 16964243 18669648
CDKN1A RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10498883 9315635 17303408 10486249 16236519 11520855 15279786 9190208 7575488 10385618 9736735 7736585 19075565 18590585 20068082 9425340 18786381 17660363 10778858 17556661
CEBPB CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9990015 19581927 10603305 15509789 16431920 19663997 15110775 7862113 10854425 17301242 24216764 20179325 15158467 17646392 18622014
DDIT3 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 7588595 21983012 11050169
MYC CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15681429 17082780 7556187 8076602 20097210 12695333 15867211 19259613
CEBPA HAMP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18671304 16946298 18326822 12183449
CEBPA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22553076 20725087 15664998 15110775 18619497 19059241 9367890 15158467 23071089 10862621 15632071 16580992
CEBPA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20506344 12914528 10956548
CEBPA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15158360 10748205 11975924
IL6 CEBPB â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 11306493 15099563 15356132 15573129 18209571 18555777 18555778 19581928 20138012 23034983 23567181 24011634 24346288 25002027 25582338 26201938 26268945 27557510 7590867 8837607 9845545
CEBPD CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7646815 18703634 7910803 11559710 18092000 1741402
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9353292 21063109 19164449 10649437
CEBPB PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7559624 11259631 18367585 11095928 14966110 12914528 15221958 18294142 11668179 17556653 10652293 21150337 20506344 18820298 18650268 16786175 10631313 10841183 22369775 19908286 16820889 11522796 15713664 16699180 16399783 10956548 11278846 10724331 16981245 18444174 14645533 16452236 12086405
CEBPB CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17067998 8654374 10818089 15722556 15388792 17599912 12857754
CEBPB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15860545 18180320 21292824 12773552 10531366
CEBPB PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23564453 19491401 18467525 24353183
CEBPB IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 8441418 10748205 21069809 1327803 7543095 11004486 9312180 23595969 15389813 12853840 7651415 7744000 9523851 19026986 17332680 8786324 8910763 11250916 23361365 11114305 7821611 21127061 9516466 10816606 1730090 8234276 15044620 9282937 16784777 20511231 1427600 24472318 7818522 10903137 23874122 8336793 22558159 14600152 19632992 9661072 14530280 1421375 11160296 9182853 22895549 25382637 9378980 9648065 24012417 11866474 8725624 12177065 8752656 11035101 18955501 2112087 15613028 9442386 9199508 7744784 15688424 8346247 22074460 17955490 12706815 11594800 11120852 10435001 8325885 19782405
CEBPB DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8051100 16757577 10085237 8662954
CEBPB LCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22851691 21612443 20220144 17447895
CEBPB GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17129742 12213825 15860545 20228168 11414683 18180320 21292824 17110376 10531366
CEBPB PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22473998 23934183 7557387 12524424 16431920 22610404 15110775 18694725 17242167 16054042 15158467 9950217 10862621 20829347
CEBPB CRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17513780 17335903 11035101 12393563 11160296 14522018 12667216 18684932 22750226 23955082 16116232 10880233 23361365
CEBPB IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21917825 12072435 9372929 16867259 20702408 17283046 10464291 16569740 10801783 15812237 22260630 10841183 10838190 10383163 9376596 17386941 10956548 12759449 11278846 12468538 11035101 11801594 2112087 12355443 15383601 16439360 19806478 22074460 16399630
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
CEBPD IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7821611 10748205 7680115 15158360 14600152 9528783 15486993
CEBPD PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7559624 10841183 19908286 16256955 20506344 10956548 18820298 16397300
CEBPG IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9916895 10841183 18247123 19806478 11474579 8999951 18438857
CEBPG IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 12177065 22389450 9655919 12219016 15389813 9621116 12200447 14754879 9950766 12626566 15158360 22558159 14600152 16798734 12215492 12115737 19782405
CEBPG PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18362203 15221958 11673276 10692422 17524357 16256955 11522796 16399783 21104307 11133817
MAFG CREBBP â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 22965115 32649885 32303435 22789539 21775727 12234984 32582032 33859744
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
KAT2B CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9687573 8684459 9687513 9445475 11864601 9267036 17496784
CREBBP RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10542243 14597638 18241676 17138826 15140884 9096323 16713569 12456660 10454579 16382138 19608861 9806899 25314079 11931769 12163591 12881425 9659924 15171256 9548485 16291753 17362989 25733689 17434128 15334063 15806143 10235267 17296604
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
CREBBP MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10944526 16713569 11463815 9238849 2176177
CREBBP NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21196497 11683914 11154691
CREBBP JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8028671 10327051 2138276 9659924 9786917 16713569 17296604 8545107 18443043 16055710
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
NFKB1 CRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17513780 11035101 12393563 17704137 11160296 12667216 18684932 16116232
MAPK14 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15649893 14580335 16648474 15371334 17072322 10747897 17255949 11274345 12697810
CSNK2A1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 34049972 15016307 10938077 27630163
CSNK2A1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17287340 19413330 22113938 18669648
CSNK2A1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22184066 23226345
CSNK2A1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17081983 15805470 26663086 27798112 18452278 26356530
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
CSNK2A1 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 19651622 11535131 17081983 8247525 8018564 18691976 9115440 20068231 18452278 19413330 7735324
CSNK2A1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15822905 17081983 16565220 18088087 29854279 2492519 34359868 25995454 1956339 16094384 15581363 18591256 16964243 92065884 15302935
CSNK2A1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 25609649 1846781 11948398 15378002 12531896 19413330 8654373 15302935 11075956 12628923 11896587 1516134 8464713 11971971 1651323 8137421 9685505 91332050
CSNK2A1 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12876286 27650555
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
CSNK2A1 FOSB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16687504 17241283
CSNK2A1 G3BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 27022092 33065005 32302571 32302572 12642610 27083003 23163895 11604510 31171631 27920254
CUL3 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
CUL3 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
CUL3 NFE2L2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
SPOP CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21988832 23331499 19256485 28216678 21577200 25011449 34599168 22911784 15897469 22013077 16524876 19261606 25278611
KEAP1 CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20534351 30273379 15983046 24896564 15282312 17439941 32341456 26219975 32296183 26757824
PPARG CXCL10 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 CXCL10 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
IRF7 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23405030 20483755 16253303 24701034
RELA CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23932714 20164184 15226358 16253303 25199798 16982926 19342664 10756005 23740952 17449583 16818736 19929594 22030901 19479051 24257594 21249144 24701034 20833730
NFKB1 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20164184 16253303 17274000 20579762 16982926 19342664 10756005 16818736 19929594 19479051 21249144 24701034
MYC DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15021909 18483244
DDIT3 PPP1R15A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17652152 31226023 15601821
DDIT3 HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17493934 18794136 21044953 19074830 18281494 22065586 15994939 18974136 24276615 19037087 22004570 18852146
DDIT3 TRIB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15775988 18940792 21068199 16949670 19164449 19566842
DDIT3 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23667408 22905241 10218478 22802018 10472808 20801537
DDIT3 TNFRSF10B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18794136 20157774 15322075 21044953 21726997 20837473 22328338 22065586 15994939 18172319 21941003 17273769 18593935
MAPK11 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15187187 19436832 15140942 20506250 8650547 21614932 16393692 11274345
MAPK12 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15187187 19436832 15140942 20506250 21614932 16393692 11274345
MAPK13 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15187187 19436832 15140942 20506250 21614932 16393692 11274345
MAPK14 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15187187 19436832 11163539 23331499 15140942 20506250 8650547 21614932 16393692 17570479 11426938 16189514 11274345
EIF2AK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17451862 16083285 1088347 10082513 10348343 10884347 16552184 9315650 9737981 19413330 16713569 10747897
MYC EIF4E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18593934 15094771 8756633 12695333 24814906 14519204 22456335 16112647
MYC EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18593934 16915296
MAFG EP300 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 22965115 32649885 32303435 22789539 21775727 12234984 32582032 33859744
EP300 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12057991 17395887 17237818 12471036
PRKAA1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11020388 21940946 12379484 15006641 12590608
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
EP300 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944526 9001254
EP300 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19608861 25400040 11567019 12419806 17617622 11533489 20333651 12456660 15152190 16846590 9096323 20064247 16382138 16713569 15171256 16135789
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
ESR1 FOSB â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 25542856 18219272 3677090 20219941 23145106 1630819 3045126 15514030 24854081 22265404 17013392 21835891 9671459 21940756
FOXO3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24062311 16807346 16809346 17575143
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
ESR1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16267616 12400015 17272396 18252963 18497067 10866309 19420388 19398483 16249470 14647449 15774498 12208749 10995484
ESR1 FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22514284 20034404
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
ESR1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20616010 20068169 16950141 21029304 19433249
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
FOXO3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11435445 15367686 16807346 18312651
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 XBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12954762 12047351 14605097
JUN FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733515 12963547 10903433 19670268
TP53 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10101800 12788915 15580300 16317104 16322229 14719118 16557594 20797428 11103825 19615968 7539102 12447615 12944915 12963547 11313989 16951143 9841917
MLXIPL FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20416398 16800817 15496471
NFKB1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11473033 16317104 10022897 16784892 7528667 19628709 9733827 10871852
YY1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16784892 17530016 16143308 11418634
VEGFA FLT1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15501236 15520864 15573129 16002046 16076871 16572188 17086423 19414323 21372296 22064427 22461508 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
FLT1 ID1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15501236 15520864 15573129 16002046 16076871 16572188 17086423 19414323 21372296 22064427 22461508 23390297 24346288 26201938 8837607 9157999 9570538 9753319
TP53 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16432214 20080630 17242190 20422012
VEGFA FLT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 15637071 9393862 8356051 10543948 21939755 8621427 16633338 21441409 35874709 8631822 14704231 17051153 20660291 26285753 22348123
PPARG FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19466435 18278065 15908479 16321227 14693716 12055599
JUN FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24342046 21479385 11052809 9756884 23744703 10325245 11896591 10421838
RELA FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10649441 18064631 10867646 22223884 12372417
MYC FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14519204 11896591 8376401 10421838
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
JUNB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1380150 2116003 8934539 11698415 9813041
FOS IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7679081 20463008 7935377 14686613
FOS FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8446579 13679379 17371847 15514944
FOS IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10037779 10542237 9671466 2511437 25567680 20351184 24994901 11356008 11028561 12667961 18502099
FOS PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15772294 11278336 9620167 17556653 12057991 8906578 17440114
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
JUN FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18435914 15806162 13679379 17082637
JUN FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9160889 11708771 23661758 20511396 11431474 24029232 11912197
JUN FOSL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25609649 26186194 9160889 11708771 20102225 26496610 32296183
MDM2 FOXO3 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11715018 11779693 11923280 14761977 15024084 15084260 15169778 15876864 16307918 17110379 17158541 19321440 20679392 9450543
FOXO3 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16840535 22563476 19608644 12027802
FOXO3 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11964479 15721278 12048180 18845647 21835778
PRKAA1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17900900 17711846 22848740 29445193
MAPK14 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22128155 23857333
FOXO3 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14976264 18644865 10783894 16288288 20673124 11094066 17646672 15509806 11994454 11154281
MYC GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15721278 9190899 10913183 15021909 14519204 9811446 21835778
TP53 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10749144 22801474 11221850 15031557 22262183 10321740 17700520 11420680 10094833 23114628 8892753 23948959 9405685 21394211 9931282 10435630 12007564 15721278 17440969 23576563 9566896 9233781 21836608 21245169 15186775 17063488 9154806 10327059 9191059 17344317 9519881 20797428 18350249 7624148 10566557 17084916 16714289 20840860 15735726 12806965 18225552 16581545
TP53 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16990795 15603758 14627995
GADD45A MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23109003 12748288 20626350 15735649
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
HDAC3 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 PPARG â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 PPARG â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17015477 16189514 12479814
HDAC3 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11486036 9346952 17925399 16189514 18940814
HDAC3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11533489 16189514 12419806
PRKAA1 HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27010499 18184930 21892142
TP53 HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15289308 16230375 11382926 15964798
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
YY1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16452489 15899857 15760841 8972185
VEGFA ID1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15501236 15520864 15573129 16002046 16076871 16572188 17086423 19414323 21372296 22064427 22461508 23390297 24346288 26201938 8837607 9157999 9570538 9753319
ID1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 12145280 9242638 15029197 8380166 20195544 9528857 1922066 18674781
MYC ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12447693 12695333 12824180 18437010 18483244 12545167
ID2 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9242638 8380166 21209940 1922066
NFKB1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RELA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
IKBKG RELA â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
VEGFA IKBKG â—¼   DOWN_REGULATES ✅ - 33.0 1.0 ACSN 10022831 11166270 11280761 11460167 11960372 12629515 13678960 14660645 15099563 15111329 15501236 15520864 15573129 16002046 16572188 17086423 17301840 18264787 19414323 21133840 21232017 21372296 22064427 22461508 23390297 24346288 24699077 24958845 26201938 8837607 9157999 9570538 9753319
IKBKG IL6 â—¼   DOWN_REGULATES ✅ - 38.0 1.0 ACSN 10542212 10754326 10952726 11875494 12133805 12907458 14660645 15199157 15465827 15485931 15536066 15644117 15749903 16243976 16413922 16818229 16878026 16970925 17237376 17254973 17363905 17404308 17485448 17693255 18716620 20138012 20300203 21217011 21807870 22435554 23086447 23390297 23422957 23430059 2649237 28462531 7594497 9743347
NFKB1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
IKBKG NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
IL15 IL6 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10426994 10952726 11907067 14607946 15536084 16713974 17398124 17459805 19913445 20007590 21307131 25582338 7523571
NFKB1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8413223 17707233 11058167 12686724 16433741 18285351 8021507 9878621 14960579 10963848 9058643 15543947 20696864 8679226 11035101 15972680 20336759 18772363 10080875 17082635
RELA IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 26596471 27338466 11114294 8413223 20975042 17707233 23383347 11058167 12686724 16433741 23667107 15382119 19122653 24009751 27211851 18566416 15292915 20617571 23056550 12517972 18285351 19843519 22267743 15812237 25161822 22388040 8021507 9878621 14960579 10963848 23195252 11395507 27534992 9058643 15543947 19846753 20696864 8679226 24908318 28389361 27371733 15972680 20336759 10080875 17082635
JUN IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11306276 18566416 7935377 10226077 14686613 16365456 11145674 17283046 20463008 23608488 8133045 8798756 18789903 16729332
IL1B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25606026 26999213 22240205 23666959 19197368 25306394 24009751
NFKB1 IL23A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17982049 20228197 17707233 17569750 21097874 19624579 18375954 19592489 17182554
RELA IL23A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17982049 20228197 17707233 20876114 19122653 17569750 21097874 19624579 18375954 19185846 19592489 17182554
JUNB IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20221401 11337499 12070012 7836389 10497240 19918056 8537375
NFKB1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 71.0 1.0 Omnipath 17513725 18061164 12058956 24337575 19124729 15611045 11058167 9523851 15517885 12887736 15158360 7876168 17495236 25549935 17982049 15241416 18243142 9516466 2405250 18996370 8824277 18310089 24664372 15749903 10903137 16112536 14532843 11327783 18942706 11975924 20066113 16984731 10975857 11160296 19703987 22895549 10963848 10469356 22547075 17040605 11459775 17490702 19469019 8247545 11504280 15756023 10569191 10823821 20696864 12907458 19707556 16043358 11035101 12176740 11302724 8679226 8725624 22578249 8752656 17196927 17532054 12727841 18057724 7499267 10329846 9199307 9502421 19164127 11120852 24676671 11098847
JUN IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 26513016 10542237 21069809 15389813 15158360 20225236 12667961 20371366 20511231 20862675 8453101 10202034 18502099 10037779 8830832 19687301 21098092 25567680 20351184 17341596 11120852 21312239 24676671
RELA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 114.0 1.0 Omnipath 26596471 19124729 10373597 9523851 23595969 28270510 21537341 17982049 15226358 18243142 12200447 20371366 24664372 23874122 14532843 18942706 10975857 21278793 10469356 22547075 17490702 11459775 23335080 10569191 19707556 19687301 7499267 8290595 23857586 24676671 18061164 11058167 12887736 15013753 15158360 22661093 20935672 20511231 17350185 10903137 16112536 27413250 21810609 16984731 16166627 18469854 12881425 24012417 23386688 22105366 8752656 12176740 27371733 22578249 18057724 20351184 10329846 19164127 10542237 11564778 20221401 15517885 19122653 20534538 7876168 27211851 9516466 18996370 8824277 18310089 21104991 25888873 12359431 11327783 20066113 20100571 19703987 19469019 21106671 16960103 18502099 16043358 21996739 20650996 22021035 11120852 12672795 12058956 18483242 22189669 14976218 17495236 11007957 21131967 11975924 27337441 9182853 10963848 17040605 11504280 15756023 10823821 17932106 19966855 20696864 12177065 8679226 9199307 17196927 20457835 21098092 17532054
MAFA INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 51.0 1.0 Omnipath 15664999 9604866 19785038 21063109 17449132 17149590 19502415 24258027 15944145 15650027 21565207 22172402 19576197 15923615 14765989 18506085 15993959 14680841 17927952 17259388 12368292 23775071 17583797 16780794 19264802 22968147 23382704 23737644 15664997 15862113 16505238 23927931 19029092 22466807 17569705 17785922 15665000 16461554 21278380 22974359 12917329 14973194 18515495 8584024 21830322 8289826 17300753 17360442 9414097 24472553 19689288
JUN INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 1310538 9062890 9270011 7862133 20424231 22563476 14578290 8264634
NFKB1 IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15265881 16982926 11877397
RELA IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15265881 16982926 11877397
JDP2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20950777 12903123 12052888 9580095
MAPK8 JDP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18307971 11602244 12225289
JUN TNFRSF10B â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 17439715 23430059 23850759 26587781 8545107
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
PPARA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10542237 17360982 18754816 15838301
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
JUN MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19268464 15212943 14767528 19940138 11414701 15777790 20353950 17116726 16000878
JUN MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2167198 19723510 1313772 8120060 8264634 1310896
JUN PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11901151 16001969 19783677 15238218 23523690 10668496 16007171 12057991 22472290 18294142 16339564 17556653 9830045 9988750 19825968 15994313 15772294 9620167 9686761 15525691 11356200 16256955 11234900 18097055 11980644 9705326 19522015 11278336 18282182 12086396 10811116 20237399
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
JUN VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9256279 11204570 11353786 23274526 11678207 17341624 20015448 8910439 16328781 11731421 15039660 19553068 20432243 7887961 12163680 10885623 11281649 14602779 18294451 15277220
RELA JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18174238 9468519 16713569 10488148
MAPK14 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12475989 17689131 17570479 25483191
MAPK8 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 202.0 1.0 Omnipath 17143273 17804415 10617656 8846788 15958389 11948398 10882101 20028971 12697749 15894542 20514406 14612408 17875713 9891069 17570479 18922473 11809792 8586671 11896587 12185592 12871843 7992057 7600582 11278395 8137421 8001819 10493750 14557262 16549498 18707149 9169478 11460167 15289320 8157646 16007099 20506250 22110360 15378002 9687508 12740383 20732415 9305638 19270716 23331499 10747973 16291755 16393692 12832416 18988627 10713700 18669648 12087092 14633987 8525045 15677475 16076903 16166642 18650425 15590691 1608942 19910486 18212344 11562357 12228228 16740711 14701799 19690332 10871633 12531896 16713569 8654373 16983342 19664995 15302935 10962563 15068801 8621542 8607977 18362184 10393177 20068231 9808624 14572659 8224842 10585392 9407028 17363973 19527717 19436832 14517282 12407442 9487126 9692890 14523011 15212693 10908726 11108663 13130464 10064600 18429822 15299005 9774977 11907583 12963725 16824735 19413330 10617104 17055484 21071413 18452278 16434970 16157600 7737130 23816567 10987838 17189706 9561845 9575168 1460037 7652575 18617513 24113186 11971971 11801649 25098452 20058876 16533805 9184210 18003900 9315636 10385525 18957422 12881422 11274345 12052834 15749833
RB1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10026157 9545246
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
MYC JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 2123531 7775604 12695333 18838534 18414489
JUNB MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19944019 16699069 19289495
MAPK8 JUNB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8917518 18669648 9889198 20068231 9405416
MAPK14 JUNB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8917518 9889198 20068231 15308641 18669648
TP53 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9266967 20094059 15153330 17611664 18945670 14614455 17293853
KAT2B MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 9659901 10944526 10619020
KAT2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 19680552 11804596 12068014 16537920 9891054 10490106 14614455 20589832 19788416 12660246 12501250 16959611 19407812 9744860 15965232 16678111 17977830 17189186
KEAP1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 104.0 1.0 Omnipath 30122040 17020408 31257023 35380342 16449638 22245129 18417180 28939422 15475350 24130096 20421418 12145307 32057361 17462537 23727018 24704364 34894983 23857982 19920073 31262713 20599909 36038548 24997453 17015834 23722832 21988832 30778200 24322982 36333711 20486933 30465941 22448038 30576774 21262351 23645672 16888629 31169361 11909699 26078718 25582950 19706542 20463144 16006525 18694732 11439354 15985429 15572695 34815381 28186440 23066931 19560419 15601839 23986495 25628777 27212020 22302998 30793592 16790436 26536456 24512214 17822677 20027226 28533375 22215675 29423025 14517290 32911434 20484052 14585973 18387606 23382044 21383067 32159343 18757741 27091842 24011591 9887101 31941496 22558124 36165926
PRKAA1 KPNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15342649 17919121 27303922
TP53 LITAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10321740 21836606 17283168 15197774
MAPK11 PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 10601328 9374491 17099248 19112161 21451146 11481440
MAPK11 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15187187 17145710 19436832 15140942 10212189 20506250 21614932 16393692 17254968 11274345
MAPK12 PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 10601328 9374491 17099248 19112161 21451146 11481440
MAPK12 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15187187 19436832 15140942 20506250 21614932 16393692 24818748 11274345
MAPK12 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK13 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 15140942 10581258 20506250 21614932 16393692 24818748 11274345
MAPK13 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK14 PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 10601328 9374491 17099248 19112161 21451146 11481440
PPM1D MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12758252 15659558 11101524 19713933
MAPK14 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17570479 11741533
MAPK14 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11439341 17599043 9190208 15355984 17380128 22279936 27642049 33419772 1756735 17996702 17570479 22895174 20871633 20223825 33219128
MAPK14 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 21675959 26247731 20213747 17535811 20506250 15657900 9315650 15642743 19413330 11283254 22975381 10581258 16083285 1088347 21614932 16393692 10884347 21050851 16552184 10747897 15187187 17906639 25789565 15140942 11258706 24818748 19436832 10781582 10212189 17172861 10348343 11078726 11274345
MAPK14 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12842894 15128824 15485852 10521409 15489227 15849198 15212693 12767944
MAPK14 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15187187 19651622 23331499 11535131 18039929 7479834 18452278 12738796 11274345
TP53 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22607268 23376463 18374905 15958553 10854211 22353755
MAPK8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 11108663 12531896 16713569 11283254 10706102 19651615 27147566 9724739 15538975 9732264 10581258 10436023 17570479 9393873 11896587 12514174 15580310 18813780 11078726
MAPK8 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19651622 10551811 17081983 18767875 20068231 91332050 1651323 1748630 16713569 11243879 18669648 15210690
MAPK8 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9030579
MYC MAX â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508165 15665468 8385351 8649388 8521822 22384171 1406956 17341548
MAX MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 17145710 16287840 25609649 12821782 16606833 16596619 21807113 25522242 20691906 19578763 24951594 8224841 17643117 9528857 12391307 16705173 21150319 10229200 21988832 15572685 9680483 2006410 17314511 14749374 12553908 17289033 17418410 19623651 12824180 17157259 12584560 26496610 20946988 20936779 8425218 23816886 17353931 10319872 17471507 18003922 16140957 20382893 12660246 8266081 7565735 32296183 10465786 26267534 17072308 27705803 9184233 18620061 10918583 17700062 10593926 10611234 16352593 9708738
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
PPM1D MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18265945 17936559 17939684
MDM2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16374512 21990374 7791904 28615518 33185004 20871633 10078201
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
PPARG MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17908458 17625041 16609149 15838654 19345798 17425848
TP53 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18980971 22451655 23048035 10029407 9343394 19853299 11792711 19939245 17088079 17258390
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
MYC VEGFA â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
MYC VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19738061 19147754 17785433 22002305 18809243 19398483 12368264 23028984
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
MYC ZBTB17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 17145710 26766587 18923429 29137325 20426839 11283613 17418410 9312026 20697356 19786833 16352593
MYOD1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 7970718 10373569 10601020 10801445 16936743 12665587 20053773
NFKB1 YY1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17438126 21725609 23178297 23572150
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18184402 17673602 16684540 15517885 12160329 15856023 18056465 20538607 17407600 20103608
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
NFKB1 TNFRSF10B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18523266 18599488 19351839
NFKB1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9266823 20669087 12471036 17673602 10827178 16210649 12466023 15517885 12622742 18294142 19618291 12067569 15655349 17556653 9988750 18973191 14988266 12871860 20103608 15555528 11082190 15234907 22001128 16820889 19766095 15997464 12349897 15387324 15368354 18057724 15547942 16624933 17767925
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
TP53 NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9249061 12403781 21683812 12167641 18372207
TP53 NFYA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17145710 16959611 15831478
PPARA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11840453 12388637 11971025 18648741 11578780 11412039 11007963 20022932 21323895
PPARA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12941763 16226723 20706641 17261671 18769491
PPARG RETN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20360975 19564408 16876120 19126543 12504108
PPARG PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11278336 16506021 19578162 20234816 10827178 14555539 11412039 19997048 20656057
PPARG PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16513826 32991581 29182484
PPARGC1A YY1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
PPARGC1A YY1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
PPARGC1A YY1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
PRKAA1 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20640476 17609368
TP53 PPM1D â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18333294 19015127 11101524 22405851 20093361
PPM1D TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15870257 17936559 23666059 28903382
PRKAA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28797070 15866171
RELA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16001969 9266823 19783677 12471036 17673602 10827178 16210649 20669087 12466023 15517885 15013753 12622742 20600530 14645117 18294142 19618291 12067569 15655349 17556653 18973191 14988266 12871860 20103608 19284764 15555528 21149600 11082190 15234907 9041934 22001128 16820889 18752821 19766095 15997464 8995303 9710122 12349897 15387324 15368354 18057724 15547942 16624933 17767925
TP53 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21187340 16713569 11687965 21763744
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
RB1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12588874 11118439
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
RELA TNFRSF10B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18523266 18599488 19351839
RELA VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18184402 17673602 16684540 15517885 12160329 15856023 18056465 20538607 17407600 20103608
YY1 TNFRSF10B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17530016 34589486 17431117 18778787
TP53 TNFRSF10B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10777207 10101800 11756185 11139340 15964798 22046379 10810622 14585074 19351839 11313989 10597242 17278883
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
TP53 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 8108142 20639906 9377555 21325822 16684540 9833779 10910082 16835303 23449391 8521408 15860260 11971180 11559575
TP53 INS â—¼   KO_DOWN_REGULATES ✅ - -1.53 1.52 PKG 28854368
TP53 TNFRSF10B â—¼   KO_DOWN_REGULATES ✅ - -1.59 1.58 PKG 28854368
TP53 FN1 â—¼   KO_UP_REGULATES ✅ + 2.36 2.36 PKG 28854368