Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
GSK3B FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20154735
MEF2D ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17108111
MEF2D MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8798771 9858528
H3F3A H3F3B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
H3F3B H3F3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3C HIST2H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3A HIST2H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3D HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3G HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3H HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3I HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3G HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3H HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3G HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
E2F4 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799066
H4C6 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATF1 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7779811
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-3B DNMT3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19834512 7297014
ATF1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10391889
SMAD4 ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10480932 23331499
TP53 ATF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
NR3C1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17016446
ATF2 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20102225 23661758
TP53 ATF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ATF3 ATF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23850759 26587781
ATF3 ATF4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 23850759 26587781
NFKB1 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24100018
ATF3 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20565867 21467165
DDIT3 ATF3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SMAD4 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9689110
CREB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16862174
JUN CREM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21757709
FOSL2 DDIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
FOS DDIT3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
DMTF1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19816943
DMTF1 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19816943
DMTF1 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21421563
DNMT3B DNMT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20426865 15362956
DNMT3A DNMT3L â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18544626 17965599
TDG DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17175537
DNMT3A TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17175537
RSL24D1 DNMT3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DNMT3L PHPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HELLS DNMT3L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17967891
NR1I3 DR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17464991 16492670
E2F4 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
TP53 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20428827
TP53 E2F4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574328 24096481
E2F4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
SMAD4 E2F4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12150994
E2F4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12789259 18319725
SMAD4 E2F5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12150994
E2F5 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12789259 18319725
EGR2 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9915863 18203138
TP53 EGR1 â—¼   COLOCALIZATION 2.0 0.8 intact 5216887 14744935
EGR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2115122 1427072
NR1I3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15268900 21389059
WT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11477071
ESR1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
GTF2H2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10949034
ESR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10037443
NR3C1 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17016446
FOS ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8557686
NR1I3 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
FOS NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20188076
FOS SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11854297
FOS RELA â—¼   PROXIMITY 2.0 0.8 intact 18172215 0705181105
RELA FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10488148
SMAD3 GMEB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
GMEB1 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
H3F3A H3F3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SMAD1 HAND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
SMAD4 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
HIST2H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19918835
SMAD4 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19079362 12296825
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
RELA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17310108 10646503
NFKB1 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17018379
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
MAX TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7969121 10348347
YY1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12039077 10030686
NR3C1 RXRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10860926 12573484
RXRA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12573484 23331499
TDG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129768
NR3C1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12573484 23331499
WT1 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20842112
TP53 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21900401
TDG SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ASH2L HIST2H3D â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3J â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3H â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3D â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ASH2L HIST2H4A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3E â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3I â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3F â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3G â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3B â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ASH2L HIST2H3A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ASH2L HIST2H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L H3F3A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST2H3A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST2H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L H3F3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST3H3 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
HIST1H3J HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3H HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3D HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3E HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3I HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3F HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3G HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3B HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
GSK3B SMAD1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 18045539 25241761
JUN ATF3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 10327051 6546308
HIST1H3A HIST1H3F â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
DNMT3A DNMT3B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
FOSB ATF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32296183
FOS ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
JUN HDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 17056544
DNMT3A H3F3A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DNMT3A H3F3C â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DNMT3A HIST1H3H â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3D â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3E â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3I â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3F â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3G â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3C â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3B â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST3H3 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
EGR1 TP53 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
DNMT3B HIST1H3J â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3H â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3D â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3E â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3I â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3F â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3G â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3C â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3B â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST3H3 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DDIT3 ATF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
ATF2 FOSL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23661758
FOSL1 ATF4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 1827203 23661758
DDIT3 JUNB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
DDIT3 FOSL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27107012 32296183 20102225 25416956 16189514
MAX E2F6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 25609649 27705803 29028833
HDAC1 E2F6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
ESR1 JUNB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 11477071
SMAD4 JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649 10220381
DNMT3B HIST2H3D â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3D â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3C â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3B HIST2H3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3B HIST2H3C â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
ATF3 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATF4 FOS â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
NR3C1 RELA â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
JUNB ATF4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21988832 23661758
DDIT3 NFIL3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
ESR1 RXRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9121466 23403292 9717844
SMAD1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15761153 9111321 18729074
H3F3B HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3D HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3J HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3H HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3H HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3D HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3D HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3I HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3G HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3C HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3E HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3B HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2BE HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3F HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3A HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2AC HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3C HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3C HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3A HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H4A HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3E HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3I HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3F HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3G HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3C HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3B HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2AC HIST2H3A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2AC HIST2H3C â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2BE HIST2H3A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2BE HIST2H3C â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
FOSL1 JUNB â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
HIST1H3B HIST1H3J â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
DNMT3L HIST2H3D â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
ESR1 ASH2L â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16603732 21502505 31527615
ATF2 ATF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25609649 26344197 31964530
PAX6 CDX2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10506141
CREM CREB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25609649 22531917 7809053 16189514
SMAD4 MAX â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16189514 12551947
H3F3B HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HIST2H2BE HIST2H3D â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
HIST2H2AC HIST2H3D â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
H3F3B HIST1H3A â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
HDAC1 MECP2 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
NFIL3 ATF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 20102225
ATF1 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 31527615
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
HDAC1 NR3C1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
ATF2 JUNB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
HIST1H3B HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3PS2 HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
NR1I3 RXRA â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
TP53 WT1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
DNMT3B HIST1H3A â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
E2F4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9724731 23060449 9858615 21102443
JUN FOSL2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 25609649
LDB1 LHX2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 32296183 20211142
SMAD3 MAX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25241761 16189514 12551947
DNMT3A HIST1H3J â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ATF3 DDIT3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DDIT3 FOS â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HIST2H3D HIST3H3 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HIST1H3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HIST1H3J HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
GSK3B SMAD3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21310903 18172167
HIST1H3J HIST2H2BE â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ATF3 ATF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20211142 23661758 20102225
FOS ATF4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25241761 23661758 20102225 1827203 16189514
DDIT3 ATF4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12805554 23661758 20102225 18330356 16189514
JUN ETS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8557686 20195357
FOS SMAD3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9732876 21829441
HIST2H2AC HIST2H2BE â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
SMAD4 JUNB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10220381 16189514 15231748
DNMT3L H3F3B â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MEF2D MEF2A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 8798771 25609649 9858528 20590529
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
CREB1 ATF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 20102225 1655749 8384217
FOSL2 ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 26186194 20102225 28514442
JUNB ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 16511568 20102225
ATF3 SMAD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20930144 12718878 16189514
NFIL3 CREB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 28514442 20102225
JUN DDIT3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23661758 10523647
TDG ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12874288 16282588
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
MECP2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14593184 12473678 16331260 14647463
SMAD3 JUNB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220381 16189514 10903323
ATF2 FOS â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
FOS JUNB â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
RXRA GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B DNMT3L â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR2 MEF2D â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
DNMT3A H3F3B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
FOS ATF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 1828107 32296183 25416956 16511568 23661758 25609649 20102225 26186194 20195357 1827203
ATF4 ATF3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20102225 19164757 23661758 16189514
NFKB1 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20303354 12360479 16618413
JUN CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20351696 9926923 24953186
YY1 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9199306 7494244 12296377
FOS DDIT3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32814053 23661758 10523647 26264872 20102225 16189514 29997244 31467278
MAX DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15021909
JUN DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19299913 22622069 12069855
DDIT3 FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10523647 16189514
WT1 DNMT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23042785
DNMT3L NUDT21 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
E2F4 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17531812 12789259 20946668
EGR1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9053449 10671503
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
TDG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12874288 17129768
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR2 MED7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR2 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20155458 10037443
ESR2 TDG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
WT1 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20842112 18212735
JUN ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1945412 8247540
TP53 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15469934 14586398
RELA FOSB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20018891
FOSL2 FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 13679379
FOSL2 JUN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
FOSL2 JUNB â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
SMAD3 JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10903323 10220381 11306568 21829441 9732876
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
SMAD3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
JUN NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 7823959 8733011
NR3C1 NFIL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19805059 23425966
NFKB1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9572484 11243407
NR3C1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12734399 9261164 9442377
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
RELA WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9572484 11243407
FOSL1 JUN â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
H3F3B HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3D â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3D â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3D â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
NR1H2 RXRA â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
ATF3 JUN â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
JUNB FOS â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218398 16511568
DNMT3A HIST1H3A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
JUNB FOSB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 28514442 32296183 12371906
JUN JUNB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 25609649 28514442 33961781
JUN FOSB â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 25609649 29020630 33961781
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
DNMT3B DNMT3L â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
JUNB FOSL1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 32296183 23661758 24029232 16189514 12371906
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
JUN FOSL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11912197 33961781 11431474 11708771 23661758 9160889 24029232 20511396 26258633
NR1I2 RXRA â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
DNMT3A DNMT3L â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
GSK3B NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 26999213 12871932 11425860 24618402 18669648 17693123
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
GSK3B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16568235 12162494
GSK3B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18201972 15465828 15280197 22761446 20537194 21194439 19345186 21660967 19997086 16407239 25629551 17183360
GSK3B JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 23331499 1846781 25979842 25241761 20537194 21278055 21397588 17482134 1516134 8384355 17570479 16023596 17215518 30086763 92065884 24632621
GSK3B SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 18045539 25241761
GSK3B NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 30250038 18838540
GSK3B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 18172167 21071413 21310903 23077590 28756206 19114991 19002158
CREB1 MEF2D â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21057636 7923378 16484497 15880109 29559111 19116276 19193899 9390517
MEF2D JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9252389 7760790 12054430
H3C2 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C2 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
H3C2 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H4C6 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H4C6 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H4C6 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
E2F4 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 11799066
H3C14 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C14 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C14 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
H3-3B DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
ATF2 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12833146 8576171 20581861 10979959 18719024
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
SMAD4 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085140
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
ATF2 ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12833146 20211142 20102225 23661758
SMAD4 ATF3 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
SMAD4 ATF3 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
ATF3 ID1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16713975 16831886 17490644 18832382 21614932 23850759 9389648
SMAD4 ATF3 â—¼   UP_REGULATES ✅ + 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
TP53 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12386811 12372430 17108111 21927023 21394211
EGR1 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17764926 21205742 16079301 16489044 18719024
ATF4 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10085237 16246168 21801305 17042743 22819556 23269699 25681212 16989641
JUN ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8576171 21304988 14667575 10979959 22870894
ATF3 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9343434 14729979 22753726 10085237
TP53 ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15933712 18431400 11792711 16169070 16713569
JUN ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10327051 25609649 1827203 14667575 20102225 23661758 8622660 20304822 8649793
ATF3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10327051 25609649 1827203 14667575 20102225 23661758 8622660 20304822 8649793
ATF4 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16006626 12082616 10085237 15775988 12083523 16246168 18940792 20020050 17276738 20732869 21044953 22802018 17726049 21966512 17455323 22691366 31226023 24939851
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
ATF4 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12805554 20102225 18330356 23661758 16189514
CREB1 RELA â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
CREB1 RELA â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
CREM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22531917 16189514 7809053 1847666
NR3C1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20203101 16713569 8449898 7621901
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
CREM FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17056544 21757709 17185632 15322221
DNMT3L DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11934864 25383530 15105426 12777184 15861382 17687327
NFKB1 E2F3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 14627988 21725609 23178297 23572150
SMAD3 E2F4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12150994
SMAD3 E2F5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12150994
RELA EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19276347 20427719 15616591 21983014
ETS1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19074849 9207063
EGR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9242687 17822668 15958557 12755686 16990849
RELA EGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19915002 19837667 10671503
EGR1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15225550 14744935 11251186 16713569 12384981
ESR1 FOSB â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 25542856 18219272 3677090 20219941 23145106 1630819 3045126 15514030 24854081 22265404 17013392 21835891 9671459 21940756
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
ESR1 FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22514284 20034404
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
SMAD4 ETS1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD3 ETS1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
ETS1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9349499 8262053 1722028
ETS1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12145208 19022222 8649821 10510472
JUN ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8557686 20195357
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
GTF2I FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9584171 12082086 11934902 16611241 10082538 19097122 11313464
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
JUNB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1380150 2116003 8934539 11698415 9813041
NR3C1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16850320 9804760 1314076 8036015 8890955 8733011
FOS FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8446579 13679379 17371847 15514944
SMAD4 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9732876 10942775
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
JUN FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18435914 15806162 13679379 17082637
JUN FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9160889 11708771 23661758 20511396 11431474 24029232 11912197
JUN FOSL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25609649 26186194 9160889 11708771 20102225 26496610 32296183
GATA1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12513776 8683991 7890725 9259412 10360378 19212333
NR3C1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15826950 16762839 18762022 18028994
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
SMAD4 ID1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16713975 16831886 17490644 18832382 21614932 23850759 9389648
SMAD1 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18381431 15331632 20522807 12296825
SMAD4 ID1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9389648 18832382 16831886 11074002 17490644
MEF2A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12574153 10330170 20590529 9252389 8355696 12016267 19389706 7760790 1406636 10403485 12054430
NR3C1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20499359 8639160 2169353 9731701
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
SMAD3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9732876 10220381 11306568 21829441 10903323
RELA JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18174238 9468519 16713569 10488148
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
SMAD3 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 25241761 16189514 12551947
SMAD4 MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 16189514 11160896
NFKB1 YY1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17438126 21725609 23178297 23572150
NR3C1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8639160 17016446
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
NR3C1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 8290595 16380507 7823959
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
NR1H2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 15604093 21071413 24561505 9199332 7760852 16189514 18988627
NR1I3 NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10924340 15557560 14683479 22363234
NR1I2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 9727070 15604093 11706036 9489701 16189514 26855179 23160820 22976785
NR3C1 NR1I3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15382119 16608920 19630272 12511605
NR1I3 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8114692 23331499 12130689 12896978
RELA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
NR3C1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 12902338 16189514 10518526
NR3C1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
WT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16713569 10744705 8389468
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368