Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TLE1 POLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PCNA GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
PCNA MDH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
PCNA ALDOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
CREB1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721872 12658356
GAPDH PCNA â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
PCNA ALDOA â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
ATM DYRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19965871
HSPB1 MFAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
YWHAG MFAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SNW1 MFAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
MFAP1 PHF5A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ATF4 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16931790
JUN ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8382609 22243239
AHCY YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ ALDOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSPB1 ANXA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATF2 SERPINB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17189429 17700520
ATF2 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20086235 10037779
ATF2 DUSP10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17681939
ATF3 ATF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23850759 26587781
ATF3 ATF4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 23850759 26587781
CEBPB ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16989641
ATF3 SELE â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10964678
ATF4 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18729081 20101207
ATF4 HRK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23090478
MAPK8 ATF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25301550 26538579
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO1 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
ATM YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ETS1 ATP2A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12119294
BACH1 GAPDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31257027
YWHAZ BCAP31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
VDAC1 BCL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0907555106 19706527
ETS1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17590421 10698492
CEBPG BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16254192 12970736
BCL2 MAPK8 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15733859 5217553
BCL2L1 MAPK8 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15733859 5217553
SMAD6 BMP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
JUN BMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19009553 18495116
JUN BMP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11044605 21898398
SMAD1 BMP7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20375015 17127702
SMAD6 BMPR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
SMAD6 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10564272 23331499
NOG BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 12478285
BMPR1A SMAD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19620713 11792802
SMAD6 BMPR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
NOG BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 12478285
SMAD4 BTRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14988407
ISY1 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMD2 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALR YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CAMK2A GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IFNG CAMK2A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
CAMK2D CAMK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20668654 1000426
IFNG CAMK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNG CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
IFNG CAMK2G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
CANX CENPQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SELE CD44 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0906074106 19889975
CD44 SELE â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7509040 21659548
CEBPA CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11867521 11684017
CEBPB MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9743233 22139077
CEBPB NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21150337 9019155
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
MLLT6 CEBPG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CEBPG SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22113278 18195020
YWHAZ CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215799 12361576
CFL1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217411 15598710
SMAD4 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9689110
CREB1 IL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
CREB1 SMAD6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
CREB1 IL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
YWHAB CSNK2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PTPN1 CSNK2A1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6732073 9600099
YWHAG DDX39B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
JUN DUSP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20702711 19585511
MAPK14 DUSP1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 20347885 8288600
EGR1 DUSP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11165042
DUSP1 MAPK12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11062068 11359773
MAPK9 DUSP10 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8214383 16288922
DUSP10 MAPK10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11359773
EEF2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
EGR1 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7011772 19057511
EGR1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21283769
EGR1 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12384981
POU1F1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18653622 9702189
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
ESR1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 19039095
ESR1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 18511507
ESR1 ITGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 MAPK12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16885352 22399296
ESR1 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673088 7539106
SAFB ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10707955
ETS1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11768239 12896968
TLE1 FUBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAZ GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
KAT5 GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
RAB2A GAPDH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15485821
HBG2 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PGK1 HDAC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1002243 26356530
HES1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18976936 25733872
HES1 TLE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19250647 16608701
HES1 TLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24270405 8687460
HMGA1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15710911 7629508
HNRNPH1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
UBE2I HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HNRNPK PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HNRNPK YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
JUN HRK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19304750 17428807
HSPB1 VDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 20566634
TLE1 HSPE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAZ HSPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SOCS3 IFNG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10421843 10064597
IMMT SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ITGA2 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
JUN MAPK10 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
JUN MAPK9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
JUN MAPK8 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
JUN SELE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9103451 9317150
JUN NPPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16251994 11799083
JUN PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16729332 20143420
JUN SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18571793 17609438
MAPK9 JUN â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19527717 7148309
JUN MAPK10 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19527717 7148309
UBE2I KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KAT5 SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP3K7 RUVBL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
MAPK14 RB1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17380128 5219804
TGFB1 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10362813
YY1 NPPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19139378 11279028
SF3A2 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
PCBP1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PDIA4 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PPIB PDIA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PGAM1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ PGK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PPIF PPIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ PPIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YY1 PRDX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
PSMD2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
RUVBL2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SUMO1 SAFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21527249 25800734
UBE2I SAFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21527249 25800734
SF3B2 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SMAD9 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD9 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
YWHAG SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TCP1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
THRB TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16236718 9254907
YWHAZ TPI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
VDAC3 VDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VDAC3 VDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT2 CCT4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
HNRNPH1 SAFB â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CCNA2 PCNA â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CANX RPN1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EED SUZ12 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MAPK8 MAPK9 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
SF3A2 SNW1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ISY1 SF3B2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PHF5A SAFB â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ATM SFN â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
PHB2 VDAC2 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
PHB2 VDAC3 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
JUN ATF3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 10327051 6546308
HNRNPA3 SF3A2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PPHLN1 SF3B2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CCT2 PFDN4 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT4 PFDN4 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
PHF5A SF3A2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA3 HNRNPK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
TPM1 TPM4 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CCT2 TCP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
HNRNPK SAFB â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ARF1 RAB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
CALU CALR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
ATF2 CENPQ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32296183
CEBPB ATF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20110283 20102225
ATF4 CEBPB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11018027 20102225
CEBPG ATF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 20102225
BMP4 CALR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CALR PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
CUL3 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 21145461
SUMO1 EGR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19057511 21354147
ESR1 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
ESR1 VAPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 SUZ12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ESR1 VDAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 PRDX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
ESR1 NACA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 TPM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 SNW1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 19934264
IMMT PHB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31536960 34079125
IMMT VDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 29128334
VDAC1 PRDX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31536960 29128334
RPN1 RAB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
SMAD4 SMAD6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15817471 9256479
VDAC1 TPM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29128334 17353931
SF3A2 SF3B2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPA3 HNRNPDL â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ISY1 MFAP1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PHF5A SNW1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ANXA5 PDIA3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27173435 24981860 26344197
ATF4 CEBPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
BATF CEBPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
CCND1 RFC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21654808 10353443
CEBPA CEBPG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
CEBPG JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23661758
ESR1 IMMT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 31527615 19805454
NFYA JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11903046 21565167
SMAD4 JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649 10220381
SF3A2 PHF5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12234937 17332742 33961781 24981860
VDAC1 RPN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31536960 26344197 29128334
UBE2I SMAD4 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217094 15231748
VDAC1 VDAC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31536960 22939629 29128334
HNRNPA3 PHF5A â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
POLB TPM4 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
SF3B2 SNW1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPA3 SF3B2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CAP1 CFL1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HNRNPDL SAFB â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
MAPK14 RB1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
MFAP1 SAFB â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
ATF3 CEBPG â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20211142 16189514 23661758 20102225
ATF3 ATF7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30833792 20102225
ATF4 BATF â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
CEBPG BATF â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
ESR1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15961505 31527615
TGFB2 TGFB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11157754 33961781 27684187 11483955
PFDN4 TCP1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HES1 TLE1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
MFAP1 SF3B2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
DUSP10 MAPK14 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
ATM CREB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15073328 17209043 16293623
MAPK8 JUN â—¼   PHOSPHORYLATION ✅ 0.85 0.85 mint 7148309 19527717
ATF7 JUN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
SMAD4 SMAD5 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
SMAD1 SMAD6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
GAPDH TPI1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
SAFB SF3B2 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PCNA CALU â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22863883 26030842
PPIB CALR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24981860 30021884
SUMO1 CEBPB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20194620 18820298
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
HDAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16469706 26487511 14722073 31527615 20348541
ESR1 MYL6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 20308691 21182205
SNW1 HSPB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25277244 20467437
VAPA IMMT â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 26344197
VAPA PHB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 26344197
RAB2A VDAC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31536960 26496610
VAPA VDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 26344197
HNRNPA3 SAFB â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PHF5A SF3B2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
MAPK9 JUN â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 9405416
PGK1 PCNA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26030842 20849852
ATF4 BTRC â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BACH1 ATF7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 20102225
BCL2 BCL2L1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HMGA1 JUN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10357819 10428834
PDIA3 PDIA4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17170699 24981860 34079125
PHB2 UQCRC1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SMAD5 SMAD4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10531362 16189514 15231748 16516194
VAPA VDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22939629 26496610 26344197
VDAC2 VDAC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31536960 22939629 30021884
BCL2L1 HRK â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PCNA UBE2I â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 PHB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
TPM1 TPM3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BTRC SMAD4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CAMK2D CAMK2G â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ATF3 ATF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20211142 23661758 20102225
CEBPG ATF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 12805554 23661758 20102225
ATF2 BACH1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23661758 20102225
BMP4 BMPR2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BMPR2 BMP7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 7644468 7791754
CEBPB CEBPA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 1840554 15751966 20102225
CEBPB CEBPG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20102225 12177065
CEBPB EGR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22260630 12947119
JUN ETS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8557686 20195357
TPM3 JUN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
NACA JUN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25609649 9488446
JUN VRK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25609649 15378002
HDAC3 YY1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CCNA2 RB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
JUN ATF7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 26496610 20102225
HRK BCL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9130713 10075695 15694340
BMPR2 BMP4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7644468 12045205 28126904 8702914 7673243
HDAC3 CCND1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16461912 20484017 12048199 15558026 15713663
SMAD4 CEBPB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12202226 12524424 16959612
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
TPM1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 1631061
SMAD6 SMAD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9256479 12857866 9436979 11483516
VDAC1 VDAC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30021884 31536960 22939629 29128334
RUVBL2 YY1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
MAPK14 RPS6KA4 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ATF2 MAPK9 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PCNA CCND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21654808 8101826 33961781 7903056 7908906 15681588
CREB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17471497 24038085 22031759
ATF2 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1387083 8382609 18385943
ATF2 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18638549 15618023
ATF2 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23443926 19491401 15767263
ATF2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17258390 22542937 15546613
ATF2 IL23A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22904313 18802055 19592489
ATF2 DUSP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17681939 20702711 24126911
ATF2 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9511728 10777595 7843287
ATF4 ATF3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20102225 19164757 23661758 16189514
ATF3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16469745 11375399 16984628
ATF4 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16026328
KAT5 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16141325
EGR1 ATP2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10625299 8977381 18612190
JUN BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14623928 17262823 19335069
CEBPB BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12970736 19717648 17043638
PDIA4 BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TLE1 BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BCL2L1 PPHLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CEBPB BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19043455
CREB1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11450946 16205321 18830594
BMPR2 BMP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25938661 7791754 10712517 10880444
ETS1 BMP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19431154 15695386
NOG BMP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10657699 12700180 11706034
MAPK8 BMPR2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PDIA3 CALR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 26344197 12052826 10436013 11823531 16189514 30021884
CAMK4 PHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689744
CEBPB CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22242598 11162569 12810706
ETS1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19499154 15579511
THRB CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15601836 18037966 12951064
CEBPB GSTP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16431954 8537397 11481261
YY1 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9199306 7494244 12296377
ETS1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10849443 19027835
CTTN YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 093880 8009870 20363754
NFYA CYC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9894911 2676721 1310523
DUSP1 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8626452 11359773
SUZ12 EED â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
EGR1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19915002 8900159
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
ESR1 SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055089 18414489
JUN ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1945412 8247540
HES1 GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YWHAB HES1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HMGA1 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8284217 7559428 8986808
JUN IL17A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22983707 21600798 23125217
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
YY1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19402223 20430007
PDIA4 PPIB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34079125 24981860 22665516 30021884
SUMO1 RNF4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24844634 23086935 29180619 32296183 15707587 24151981 24907272
RNF4 SUMO1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
YWHAG SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
YWHAZ SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
SFN YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
SFN YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
DUSP1 MAPK14 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
KAT5 RUVBL2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CWC15 SF3B2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CWC15 PHF5A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
SF3B2 SNW1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
GAPDH PGK1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
ATF2 MAPK8 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
BMP4 BMPR1A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CCT4 TCP1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
ATF3 JUN â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
SF3A2 YY1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
PHF5A SNW1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
BMP7 NOG â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CWC15 ISY1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CALR CALU â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
ATF4 CEBPG â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
TLE1 HES1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 33961781 19321451 18611861 19956621 8687460 24270405
SUMO1 JUN â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 11867732 15469925 10788439
CDK4 RB1 â—¼   PHOSPHORYLATION ✅ - 0.93 0.93 Signor 9139732
ISY1 SNW1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
TPM3 TPM4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 22939629 32296183
SF3A2 SNW1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATF2 MAPK14 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CCND1 RB1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
PRKCE YWHAZ â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
SMAD4 SMAD9 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
CAMK2A CAMK2B â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAMK2B CAMK2D â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
JUN MAPK10 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
POLB S100A10 â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
CWC15 SNW1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CWC15 SF3A2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CAMK2A CAMK2D â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
BMPR1A BMP2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 19804412 7261592
MFAP1 SNW1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CDK4 PCNA â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
JUN MAPK9 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
PHF5A SF3B2 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
MFAP1 SF3A2 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MFAP1 SF3B2 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
BMP2 BMPR1A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CYC1 UQCRC1 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
PHF5A SF3A2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CDK4 RB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PCNA RFC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD2 USP14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SF3A2 SF3B2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EED SUZ12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
JUN MAPK8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BMP10 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16049014
BMP10 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15621726 16049014
PCNA POLB â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 16442856 16697054 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
POLB PCNA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
PCNA POLB â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 16442856 16697054 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
JUN PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22550165 19940138 1352831 15205327 23078099
PCNA RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8999859 12400013 15225546 19285992 10353443 12192049 9649448 26496610 12045192 12171929 24958773 8861969 9092549
BMP5 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11580864 16189514
DYRK2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20831597 22307329
JUN CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 18684922 16701870 24048734 14686613 24284797 15057743 12643600 17197543 11864912 10817569 12218154 22031759 17586662 10969814 19064995 12716652 27856305 25582859 17471497 22095787 16818736 23176534 14670967 18435575 16846747 19734226 16299055 14612204 18772138 19132242 12209633 15939312 16834785 11399048 11120852 25567680
CEBPG CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12177065 8530498 15223809 8413306 20388952 8207232 9271387 18824136 18199703 18850010 19734226 8999951 12561382
ESR1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15208657 16029657 19440537 14991571 18669446 17932106
CEBPA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22685373 25119735 8999951 18199703
CEBPB CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 23051921 10775602 17135982 8969274 17997161 18512730 21471847 24554449 14645117 15085176 17845418 12707271 12748173 19489038 22031759 8234276 19064995 8207232 16989899 27856305 11991987 19109189 17471497 19786303 16809637 16818736 21255844 19734226 24038085 18772138 19805069 20861254 18487355 11390611 15688424 10462040 16803583 8999951 11120852
SMAD4 ARG1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 6357187 8515656 8871614 9389648
CEBPB ARG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9013624 15922518 19805133 8612622 23913966
EGR1 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789819 7829523 9571041 7559515
ATF2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9990041 10915780 11850817 11410592 11739785 15691880 16405968 10464245 10500157 15314161 10066798
ATF2 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16452470 12196528 15663480 17896792
ATF2 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12833146 8576171 20581861 10979959 18719024
ATF2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18641343 12836278 20006311 20304822
ATF2 TGFB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8119953 1400310 26225425
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
ATF2 IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17496231 22065573 10848607 18272195 20048166 16641293 7972056
MAPK8 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 11279118 17081983 20506250 12958075 9162092 19255142 8654373 20028971 15105425 17626013 12788955 11566021 15550563 10777545 23331499 7535770 15068801 21071413 17875713 9317150 16393692 15304344 18988627 7737130 26538579 21444723 602896 11896587 12110590 7824938 11274345 12874243 11971971 9399639 19436832 16533805 9670022 9029150 11865055 9207092 12804775 7737129 15212693 9405416
MAPK9 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 17145710 17081983 18767875 20506250 25416956 19255142 19413330 20028971 8654373 12788955 11994493 11566021 10777545 7535770 8709204 17875713 20068231 16393692 15192015 7737130 18669648 10066798 602896 11896587 12110590 32296183 11971971 19651622 19436832 16533805 11865055 19822663 11823524 31515488 7737129 11274345
PLK3 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21098032 21296815 20068231
MAPK14 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 17081983 18767875 21098032 20506250 26359454 19690332 11060298 19413330 12788955 10085140 22037767 11566021 17079470 19647037 10581204 10777545 7535770 23331499 7839144 19324872 21071413 21614932 20068231 16393692 15304344 17570479 17380123 18988627 7737130 18669648 15187187 9305639 7737129 15140942 602896 11896587 17548358 12110590 7824938 8663524 33893075 12024021 11078583 11971971 9707433 17258390 10821277 19651622 19436832 11259586 27726305 11781825 9430721 27142525 10909971 12118074 15569672 15212693 9753474 11274345 10903740 26987986
MAPK10 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19436832 20506250 16393692 8654373 20028971 11274345
PRKCE ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24727247 22304920 24357804 25545367 26645581 25728676
VRK1 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20140229 1661585 26706601 15105425 92095966
ATM ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 24357804 25545367 15916964 28212892 25689427
SMAD4 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085140
RB1 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1641004 11566021
MAPK12 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 15140942 20506250 9029150 21614932 11238375 16393692 10085140 11274345
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
ATF2 ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12833146 20211142 20102225 23661758
SMAD4 ATF3 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
SMAD4 ATF3 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
SMAD4 ATF3 â—¼   UP_REGULATES ✅ + 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
EGR1 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17764926 21205742 16079301 16489044 18719024
ATF4 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10085237 16246168 21801305 17042743 22819556 23269699 25681212 16989641
JUN ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8576171 21304988 14667575 10979959 22870894
ATF3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20203264 24317040 17785797 24951825 20351107 22105779 16688168 18942706 17766920
JUN ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10327051 25609649 1827203 14667575 20102225 23661758 8622660 20304822 8649793
ATF3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10327051 25609649 1827203 14667575 20102225 23661758 8622660 20304822 8649793
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
ATM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 16293623 15073328 17525332 15212693 23642045 19115993
ATM HMGA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17570479 20123066 17525332 21339738 18783938
ATM SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22588298 23277204
CAMK2A ATP2A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7929371
BATF IL17A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19578362 22983707 24584090 23203924 21572431
BCAP31 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9334338 17145710 12594175
BCAP31 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9334338 17145710
BCL2 HRK â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532 9130713
CUL3 BCL2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
ESR1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19148464 19160418 9306964 11261829 21841772 10542244 20664923 18414489
CEBPA BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16254192 18987666 23814099 15713621 12970736
BCL2L1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18835031 14980220 26186194 11583631
MAPK14 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 29050237 16714293 19336399 11495898
HRK BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10075695 9130713
MAPK8 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 12421819 26609913 17097560 16738310 21726807 10567572 21993018 29950132 20919655 22848813 15225643 19029119 9738012 18570871 9115213 12039864 11323415 15733859 18471544 15703383 23329792 10677502
PLK3 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21336504 21840391
HRK BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 9130713 16697956 21731739 15694340 10075695 14596824 15031724
MAPK8 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 10617621 25241761 15733859 12633850 18471544
BCL2L1 VDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12767928 17209561 16189514 10365962 10737788
SMAD1 BMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14551209 11786386 21471203 19836350 11585340 22072987
NOG BMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10657699 12700180 19804412 15064755
BMP2 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10880440 23331499 11263668 23180781 18342887 16446785 10880444 10712517 7791754 17295905 25938661 24337809
BMP2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 51.0 1.0 Omnipath 17145710 17483092 10880444 10712517 26330344 21054789 16672363 10881198 11263668 20860622 15064755 18937504 25938661 15621726 12700180 10692589 19804412
BMP4 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 8702914 26330344 20860622 21054789 11241215 8006002 16189514 7644468
BMP4 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8702914 23331499 21071413 16446785 12045205 8006002 7673243 7644468
NOG BMP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17145710 12478285
BMP7 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16189514 7791754 12297674 8605097
BMP7 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18342887 16446785 7791754 7644468
BMPR2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18756288 7791754 10712517
BMPR1A SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11438941 24412244 19620713 9136927 16189514 11792802
BTRC SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15855639 15314162 16865698 26022109 25373906 16189514 14988407
CALR PDIA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
CAMK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8065343 15733869 7608156 1646483 9770464 9829964
MAP3K7 CAMK2A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12556497 10380924 10391246 10488343 12482967
CAMK2A CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1314426
CAMK2A CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11175347 12356771 15733869 1646483 11160957 9668047 7958915 9829964 12235136 11970864 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11013247 11909979
CAMK2A TH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 7901013 1347949 11359875 24055376 1680128 16626642 34031189 17570479 34238765 6150037 11502746 12421349
CAMK2A ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 25024220 12475968 25117710 20435626
CAMK2A CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19582779 9580567 1281449 12032545 16785995 22865879 11463356
CAMK2B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
CAMK2B ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12475968
CAMK2D CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11175347 12356771 15733869 22554507 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
CAMK2G TH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 1680128 7901013 11359875 6150037
CAMK2G CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
CAMK4 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 11175347 12356771 15733869 11160957 8195196 7958915 9829964 12235136 9687510 7864890 8887554 11698596 11970865 8688081 17389598 9528766 12835716 11018520 11969286 11909979
JUN CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9486962 23385061 15574764 17182846 15737994 21069729 9511728 20531301 21029732
CREB1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11160720 20857405 8641461 17325033 12869629 19343785
RB1 CCND1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
JUN CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16393119 21135252 8917510 17166846 19622016 11402335 20220142 22853846 17670745 10567390 17496887 19499154 9878062 21474819 17278098 15282324 15467760 15994313 14672732 15574422 22550166 10066798 17637753 20482821 15574764 11745411 11410592 18084253 20037604 12794082 10790372 16860316 24190040 17501623 17477349 19435822 10500157 11432833
EGR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23872169 20590664 16926376 19850937 11502738 16267018 16547599 9407106
CREB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23447091 16503642 18957421 9990041 12504100 10915780 15116100 22271686 14764597 16522741 18713830 24065533 10201372 22751440 18988190 12391146
JUN CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
CCND1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 10498883 9315635 17303408 16236519 11520855 15279786 9190208 7575488 10385618 9736735 8490963 26225123 19237565 7736585 19075565 18590585 27507850 26121043 20068082 9425340 18786381 17660363 10778858 9380698 27430527
EGR1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12670907 8628295 20357818 15155664 8666932 15923644 8773576
RB1 CDK4 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
CDK4 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 107.0 1.0 Omnipath 26203195 10498883 23336272 9315635 17303408 17363486 25803170 10359571 15081408 16236519 28249908 16936279 17478427 19690332 11520855 31615938 15279786 16326706 18981099 9190208 8626527 14627988 7575488 24417566 9003781 16360038 10385618 9736735 9139732 7736585 20068231 34158578 16189514 19075565 18669648 11773438 11641415 21880723 18590585 27708221 10962560 20068082 15489884 9425340 19225156 19551155 17045206 10210318 19262748 18786381 17660363 17621266 19651622 12657252 11746527 11254678 15809340 22263797 10202152 10778858 27811360 23981302 19664994 14676836 9380698 18583321 23429262 27430527
CEBPB CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9990015 19581927 10603305 15509789 16431920 19663997 15110775 7862113 10854425 17301242 24216764 20179325 15158467 17646392 18622014
CEBPA SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19332118 18212493 20351777
CEBPA GAPDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12842822 7864870
CEBPA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15158360 10748205 11975924
IL6 CEBPB â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 11306493 15099563 15356132 15573129 18209571 18555777 18555778 19581928 20138012 23034983 23567181 24011634 24346288 25002027 25582338 26201938 26268945 27557510 7590867 8837607 9845545
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10995751 15878863 16331681 17556653 19521987 11312260 11009091 8634139
CEBPB IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15048722 19915002 16585579 12516545 7594540 15922518 8709636 9442389 11009091 23913966
CEBPB PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23564453 19491401 18467525 24353183
CEBPB IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 8441418 10748205 21069809 1327803 7543095 11004486 9312180 23595969 15389813 12853840 7651415 7744000 9523851 19026986 17332680 8786324 8910763 11250916 23361365 11114305 7821611 21127061 9516466 10816606 1730090 8234276 15044620 9282937 16784777 20511231 1427600 24472318 7818522 10903137 23874122 8336793 22558159 14600152 19632992 9661072 14530280 1421375 11160296 9182853 22895549 25382637 9378980 9648065 24012417 11866474 8725624 12177065 8752656 11035101 18955501 2112087 15613028 9442386 9199508 7744784 15688424 8346247 22074460 17955490 12706815 11594800 11120852 10435001 8325885 19782405
CEBPB SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14576184 21292824 18195020 19423709
CEBPB DUSP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18682532 18761321
CEBPG IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 12177065 22389450 9655919 12219016 15389813 9621116 12200447 14754879 9950766 12626566 15158360 22558159 14600152 16798734 12215492 12115737 19782405
CEBPG NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10198420 14754879 19323834 11474579 12048217
CREB1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8725624 19342597 20100571 20160059 11701462 16424113 18617614 19162127 15467434 21209948 23874122 17495236
CREB1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20979795 11907114 20006311 12928400 16713974 22413812 7759501 12626576 9834094 15879136 20685939 18641343 9503023
CREB1 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16893419 10407170 15240392 20367754 11238722 16452470 9645965 11108136 9038229
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
CREB1 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15319449 11081181 21586695 24078059
CREB1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20359506 17451429 17018277 21156859 11557984 22980225 15653680 19583954
CREB1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11313407 12370343 17548609 12626549 15993752 12432566 8670878 8814256 11238674
RPS6KA4 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 11175347 12356771 15733869 11160957 23331499 9792677 9829964 7958915 12235136 9687510 17158541 15187187 18813292 17668895 8887554 11698596 8688081 9528766 11018520 11969286 11909979
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
MAPK14 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11175347 12356771 15733869 11160957 11532940 7958915 9829964 12235136 16189514 11335727 9687510 8887554 11698596 23532963 8688081 9528766 11018520 11969286 11377386 11909979
MAPK14 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15649893 14580335 16648474 15371334 17072322 10747897 17255949 11274345 12697810
CSNK2A1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22184066 23226345
CSNK2A1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17081983 15805470 26663086 27798112 18452278 26356530
CSNK2A1 TLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22354967 15367661 20558317 20976471
CSNK2A1 EGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8662759
CSNK2A1 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11062067
CSNK2A1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 25609649 1846781 11948398 15378002 12531896 19413330 8654373 15302935 11075956 12628923 11896587 1516134 8464713 11971971 1651323 8137421 9685505 91332050
CSNK2A1 HSPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10772927 12558502
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
PTPN1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 27824079 18515860 18387954
DUSP1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 9020184 18813292 8626452 9202001 11278799
DUSP1 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19741200 11278799 27880917 23331499 7535770 8626452 9202001 11359773 20626350 20936779 25241761 18813292 20347885 12356755 18723442 17158101 12758252 15659558
DUSP10 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 10597297 10391943 11790549 11283254 16166642 26538579
DUSP10 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16288922 10597297 32296183 11359773
DUSP10 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 20936779 10597297 10391943 11790549 11157753 11359773
DUSP8 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 26186194 8910287 10915787 21071413 9922370 21900206
DUSP8 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 8910287 10915787 23159405 9922370
ETS1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19074849 9207063
EGR1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18281687 24453276 23632636 15517885 23184950
EGR1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19915002 10656874 12560487 9756940 7673240 20680391 8773576 17142725
EGR1 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16515541 20965158 20124442 12670703 10842166 24227652
EGR1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17916653 20417179 8794351 8058069 8051207 26279418 10783396 16138117 8876223 20690147 16702209 11707452
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15833836 10960840 11174852 8923463
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
PHB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15140878 17932104 26052702 10938099 12943695
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
SMAD4 ETS1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
TGFB1 ETS1 â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 7594497 9157999 9335507
ETS1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7876544 9780181 24019486
ETS1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16127276 15247905 11556732 20645833 9185999 10211993 8683934 18772901
JUN ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8557686 20195357
HDAC3 NOS2 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11486036 9346952 17925399 16189514 18940814
HMGA1 IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8986808 8934574 1330326 8374955 7972056
HMGA1 SELE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7520524 7523851 9016563 10090829
HMGA1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10085153 18279675 11056164 14630716 18937643
HMGA1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8934574 8896456 10848593 10706706
MAPK10 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 53.0 1.0 Omnipath 17081983 20166139 18767875 17322306 20230923 19413330 11231586 19664995 19415658 15302935 16083285 20068231 18452278 18669648 18691976 11259409 17287340 19651622 15212693 17924679 19664994 16964243 10329716 18212344
MAPK8 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11259409 11231586
JUN IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9660935 18035482 22065573 10848607 20048166 22083261 17376932
YY1 IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12584314 16954376 18225953 22287632 22065573 16260628
IL4 IFNG â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
SMAD4 IFNG â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 6357187 8515656 8871614 9389648
JUN IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20006311 22123848 14734615 15187132 11943142 20304822 17556653 1314139 17105733 22413812 19265145 11801649 16713974 7759501 12836278 15522880 12626576 9558063 8756632 18641343 22351517
JUN IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 20557936 12370343 10700231 12884855 8436291 9541574 8397339 1737937 9605137 8683110 21832163 9590239 7989759 9774418 16116194 8473495 8114694 10878360 10320367 9233628 7642615 17097050 7565732 8468462 8660843 7739550 8051409 1740667 19181930
IL4 IL23A â—¼   DOWN_REGULATES ✅ - 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
JUN IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8996240 10772943 9889198 9133600 21989417 9310836 15546613 21454593 12594266
JUN IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 26513016 10542237 21069809 15389813 15158360 20225236 12667961 20371366 20511231 20862675 8453101 10202034 18502099 10037779 8830832 19687301 21098092 25567680 20351184 17341596 11120852 21312239 24676671
JUN NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17105733 17940019 16421203 18596035 11254551 14962367 14686613 16771680 9776360 12788789 12020969
JUN TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8058069 16327802 16730810 23437118 8183578 16365456 22429882 23936544 15546613 10843986 16978906 23762330 7521696 8631909 12794825
VRK1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8137421 29029460 11896587 11948398 15378002 26412148 12531896 8654373 11971971 15302935 21386980
MAPK14 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12475989 17689131 17570479 25483191
UBE2I JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11877416 16713569 16055711 10788439 8733011
MAPK8 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 202.0 1.0 Omnipath 17143273 17804415 10617656 8846788 15958389 11948398 10882101 20028971 12697749 15894542 20514406 14612408 17875713 9891069 17570479 18922473 11809792 8586671 11896587 12185592 12871843 7992057 7600582 11278395 8137421 8001819 10493750 14557262 16549498 18707149 9169478 11460167 15289320 8157646 16007099 20506250 22110360 15378002 9687508 12740383 20732415 9305638 19270716 23331499 10747973 16291755 16393692 12832416 18988627 10713700 18669648 12087092 14633987 8525045 15677475 16076903 16166642 18650425 15590691 1608942 19910486 18212344 11562357 12228228 16740711 14701799 19690332 10871633 12531896 16713569 8654373 16983342 19664995 15302935 10962563 15068801 8621542 8607977 18362184 10393177 20068231 9808624 14572659 8224842 10585392 9407028 17363973 19527717 19436832 14517282 12407442 9487126 9692890 14523011 15212693 10908726 11108663 13130464 10064600 18429822 15299005 9774977 11907583 12963725 16824735 19413330 10617104 17055484 21071413 18452278 16434970 16157600 7737130 23816567 10987838 17189706 9561845 9575168 1460037 7652575 18617513 24113186 11971971 11801649 25098452 20058876 16533805 9184210 18003900 9315636 10385525 18957422 12881422 11274345 12052834 15749833
PLK3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17804415 21296815 19690332 19413330 18650425 18669648 15302935
MAPK9 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 17143273 17145710 17637567 12584171 20506250 11948398 15378002 16824735 9687508 8654373 20028971 12788955 9305638 15302935 26091349 33822843 18362184 17875713 16393692 9405416 17570479 1922387 18252863 25561726 7737130 10490605 17189706 11896587 34408980 11274345 20178741 8525045 16076903 7992057 19527717 7600582 17215518 8985011 11801649 19118012 11278395 8001819 8137421 19436832 16533805 8945519 12881422 9315636 10385525 12093796 14523011 19910486 15212693 8157646 12040039 11562357
MAPK10 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17143273 20506250 16824735 8654373 20028971 16007099 21988832 12167088 16393692 1922387 16076903 22327296 19527717 21757544 19436832 17670986 14523011 11274345 20395206 11562357
RB1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10026157 9545246
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
SMAD6 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11737269 10748100
MAP3K7 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15692051 17947236 11865055 17965022 17186025
MAP3K7 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12589052 17965022 15692051 17947236
MAPK10 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15071501
MAPK10 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15071501
MAPK12 PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 10601328 9374491 17099248 19112161 21451146 11481440
MAPK12 RPS6KA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15187187 19436832 15140942 20506250 21614932 16393692 11274345
MAPK14 PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 10601328 9374491 17099248 19112161 21451146 11481440
MAPK14 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17570479 11741533
MAPK14 RPS6KA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 10806207 17145710 23602568 20506250 11035004 23331499 21614932 20068231 9792677 16393692 10922375 17570479 25852190 15187187 26186194 15140942 18691976 18813292 19651622 19436832 11157753 16964243 11274345
MAPK14 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11439341 17599043 9190208 15355984 17380128 22279936 27642049 33419772 1756735 17996702 17570479 22895174 20871633 20223825 33219128
MAPK8 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 7890696 15696159 15071501
MAPK8 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15071501
MAPK8 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 18985696 25862939 15696159 11956222 19788416 21081103 15071501 18559254 7890696
MAPK9 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15071501
MAPK9 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17570479 15071501
SMAD4 NOS2 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 6357187 8515656 8871614 9389648
PLK3 VRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20068231 17617371 19103756
PPARGC1A YY1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
PPARGC1A YY1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
PPARGC1A YY1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
RB1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12588874 11118439
SMAD1 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10692396 17215250 22219353 22072987
SMAD6 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9256479 9335505 9436979 21071413 18988627 11483516 12857866
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
SMAD4 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10964912 15647271 10843986 21968601
SMAD5 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20957627 23331499 14534577 16516194 16189514 10531362 15231748
SUMO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14514699 23331499 21071413 12813045 12740389
UBE2I SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 21988832 31515488 16189514 15637079 16713569 12621041 29892012 15231748
SMAD9 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20957627 25502805 10583507 31515488 16189514 15231748
SMAD5 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10692396 16436528 22219353
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
ATM S100A10 â—¼   KO_DOWN_REGULATES ✅ - -1.21 1.2 PKG 28854368
POLB HNRNPDL â—¼   KO_UP_REGULATES ✅ + 1.55 1.55 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368