Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
JUN JUND â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8922393 2504580
GRB2 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
EGFR H3C2 â—¼   COLOCALIZATION 2.0 0.8 intact 5216105 12577067
ACTA1 ACTC1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
GRB2 ACTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ACTN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
ACTN4 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
TPM3 C1ORF216 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
C1ORF216 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TPM1 CBS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TPM1 CCDC112 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STAT1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19061877
SYCE1 CNN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DAPK1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DAPK1 PRKAG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
GRB2 DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
RIPK3 DLD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29358703
TGFBR1 DLG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8426596 23624079
DLG5 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GRB2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
STAT1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10558875 22693070
EGFR PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 1845983
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
STAT5B ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11731618
ESR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10037443
PIK3CA FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TPM1 GALNT18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PIK3CA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 SPTBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TPM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
STAT1 IRF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19161415
KXD1 TPM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MAD1L1 TPM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MEF2A MYH6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15737621 9111345
MEF2A TNNT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18951515 16049055
MEF2A MYH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15728583
MEF2A MYH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15728583
TPM3 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SPTBN1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TPM1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNNC1 TNNI3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TPM1 TNNT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
GATA4 NKX2-5 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ATF2 JUND â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ACTA1 TNNT2 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ACTN1 ACTN2 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
TNNC1 TPM1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
TPM1 TPM4 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
KXD1 TPM1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
TPM3 JIP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TPM1 JIP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ANLN DREB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
DREB TPM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 26496610
ACTC ANLN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 30890647
COX41 VDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 29128334
COX41 TPM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 26344197
COX41 TPM4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 26344197
CCD96 TPM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32296183
ANLN ACTN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN ACTN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN TPM4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN TPM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN TPM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN TPM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
CFTR EXOC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
EGFR EXOC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25594178 23956138
FOS ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
ESR1 TPM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
FAM9C TPM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32296183
LRRK2 VDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 21370995
TPM2 TPM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22939629
TPM2 TPM4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22939629
VDAC1 TPM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29128334 17353931
ACTA1 TNNC1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
ACTN2 ACTN4 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EGFR STAT5B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 11751923
JUN JUND â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649
TSSC4 TPM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPM1 HOME1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DREB HOME1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
TPM1 NEMO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPM1 NUCG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPM1 KLH21 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPM3 KXDL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 32296183 25910212 25416956 16189514
TPM1 C102A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ESR1 ACTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23403292 31527615 19805454 21182205
ESR2 ACTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21182203 25604459 29509190
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
TPM1 CNTLN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPM1 CROCC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPM1 DLG5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPM1 EXOC4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SIX1 MYH4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPM1 RUFY2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPM1 SCLT1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TPM1 SYCE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25416956 25910212
TNNI3 TPM1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
GRB2 DREB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25814554 12577067
ACTA1 TNNI3 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ACTA1 TPM1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ACTN4 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21078666
TPM3 MAD1L1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 8153045 21516116
ACTC DREB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 30890647 30021884
ACTC TPM1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 30021884
ESR1 DNM1L â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 19805454
ESR1 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 16651450
ESR1 STAT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 25303530
TNNT2 TPM1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
JUND ATF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 20102225
TPM1 MD1L1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 32296183 25416956 25910212 26871637 26186194 28514442
TPM1 KXDL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 32296183 25416956 25910212 26186194 28514442 16189514
CNN1 TPM1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 2161834 2455687
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MYH6 TNNI1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TPM1 TPM3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EGFR STAT1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TPM1 TPM2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
TPM1 JUND â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28514442 26186194
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
TPM3 JUN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EGFR NEMO â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR ACTN4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 26320552 25402006 24658140
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
TPM1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 1631061
JUND MEN1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ATF2 FOS â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
TNNC1 TNNI1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
GEM ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FOS JUND â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
JUN ACTA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1460048
FOS ACTA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1460048
FOS ATF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 1828107 32296183 25416956 16511568 23661758 25609649 20102225 26186194 20195357 1827203
LRRK2 DNM1L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24282027 22228096 22639965 23813973 29541021
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
STAT5B ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11731618 11682625
ESR2 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20155458 10037443
FN1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18624398 19738201
STAT1 IRF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10092656 16918696 19074829
STAT1 ISG15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16009940 17312100
TNNI3 TNNC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15049709 33961781 12840750 18986304 11904166 12122471 12060657 29997244 7957210 12939162 15134451 16302972 9346285
TPM2 TPM1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 7568216 22939629 26186194 3857586 28514442 30021884
NHEJ1 TPM1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
TPM3 TPM4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 22939629 32296183
TNNI3 TNNT2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ACTN1 ACTN4 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
TNNC1 TNNT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
TNNC1 TNNI3 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
JUND FOS â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 12193410 35140242 11431474 20195357 26496610 25609649 20102225 26186194 24029232 15867431 28514442
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ESR1 JUND â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 25542856 18219272 3677090 20219941 23145106 1630819 3045126 15514030 24854081 22265404 17013392 21835891 9671459 21940756
MEN1 JUND â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 12509449 12226747 16651450 10500243 22327296 16997566 9989505
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
ATF2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
ATF2 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21479385 8335091 10471826 8703044 9151819
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
DAPK1 TPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23157718 25890206 17895359 33389411
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10830280 10358079 12411494 10558875 16729043 17016520 11751923
EGFR STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 23956138 12070153 11839738 10918587 11447289 11997436 14967450 25402006 12040186 24797263 15173823 7543024 15322115 10358079 6321473 11294897 7690989 10982844 19568798 12637327 14585353 15199124 17496910 11438544 10748192 24658140 7657660 12817007 31980649 22693070 9355737 19615955 11152457 15284024 15567848 7592750 16488589
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
STAT1 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16494848 23086340 19556344
JUN FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9456251 10913304 10559225 11281649 11551904 23485603 23331079
JUN FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24342046 21479385 11052809 9756884 23744703 10325245 11896591 10421838
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
STAT1 FOS â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
STAT1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8874187 7510676 8830676 12600988 7507205 8770944 17558387
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
NKX2-5 GATA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19479054 15653675 16137232
GATA4 MYH6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23284745 11994297 8007990 15902305
STAT5B GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
JUN GRB2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
JUN ULK1 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11001584 11274345 16054035 16396903 16406505 16880536 17000779 17439715 17638910 18754008 18813803 19081070 19190345 19219074 20107231 22354771 23031257 26587781 8545107
MEF2A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12574153 10330170 20590529 9252389 8355696 12016267 19389706 7760790 1406636 10403485 12054430
LRRK2 SNAPIN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23949442
PIK3CA TPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16094730
STAT5B SPTBN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 31066629 17764812 19345670 23168613
STAT1 STAT5B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
MUS81 TPM1 â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
NHEJ1 CNN1 â—¼   KO_UP_REGULATES ✅ + 1.5 1.5 PKG 28854368
NHEJ1 FGF2 â—¼   KO_UP_REGULATES ✅ + 1.54 1.54 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368