Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATM H2AX â—¼   COLOCALIZATION 2.0 0.8 intact 16858402 5218840
H2AX XRCC1 â—¼   COLOCALIZATION 2.0 0.8 intact 19851285 7542621
MYH9 CCDC124 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCDC124 PA2G4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CAD IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CRK SHANK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK3 ARPC5L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 DCTN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 DBNL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 PSMD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CRK ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL2 CRK â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15886098 5217726
ESR1 ARHGDIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21447808 11060289
ATM STRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18833288
BTF3 EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17312387
CSNK2A2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10938077
DCTN6 DYNLRB1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
DNAJA1 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DNAJA1 STIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
DNAJC7 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EIF2S3 RPS21 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EIF3I EIF3G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219314 17094969
ESR1 EPHB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17685427 20484412
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
TXN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19737086
HINT1 TRIM29 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8216426 7644499
TXN HMGB1 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 18996119 6795958
HNRNPK PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PARP1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SLC25A5 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS3A IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPN1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYH9 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TXLNA IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NFKB1 MADCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15483224
MYH9 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10639334 10047984
NAP1L1 PSMD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
RUNX1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19686049
PA2G4 RPSA â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PA2G4 RPS19 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PA2G4 RPS21 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PA2G4 RPS11 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PA2G4 RPS3A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PA2G4 RPS28 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PAK3 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PARP1 RAD23B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
PARP1 RNH1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086497 21276451
RRAS2 PAWR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SRSF3 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TOP2A PIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11940573 5215253
RAD23A PSMD4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
STIP1 PTGES3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21183720 16403413
RPS19 TRMT112 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RPSA RPS21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RPS28 TRMT112 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RPS3A TRMT112 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBE2Z SRA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XIAP TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CHMP4A CHMP5 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
MCTS1 RPS3A â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
ASNSD1 PDRG1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DNAJB1 HSPH1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
NUBP1 NUBP2 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
TUBB4B UBE2V1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MCTS1 RPSA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
EIF3G EIF3I â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MCTS1 RPS19 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
MCTS1 RPS21 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
RPS11 TRMT112 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
RWDD4 ZNF330 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
VHL ATM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16678111 17353931
CIAO1 GLRX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27519415 23891004
SKP1 ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 23770852
ESR1 VAPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
VHL MIF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21942715 17353931
PCBP1 SRSF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 16713569
SKP1 PSMF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27705803
VAPA RAI14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MCTS1 RPS11 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
XRCC5 YARS â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EIF2S3 RPS19 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
GSPT1 RPSA â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
RPS21 RPS28 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MCTS1 RPS28 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
GMFB PPM1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
H2AX XRCC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20085707 21679440 18406329
BTF3 TXLNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25416956 33644029
RUNX1 CBFB â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 17431401 5219852
EIF2S3 RPS3A â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
RPA2 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 11953755
TTC1 VAPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 26496610 26186194 28514442
SKP1 UBE2D2 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
RPS17L RPS19 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
ESR1 MTA1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
EEF1B2 RPL6 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
GSPT1 RPS3A â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
GSPT1 RPS21 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ESR1 PA2G4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
GSPT1 RPS11 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
GSPT1 RPS19 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CHMP4A VPS4A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
GSPT1 RPS28 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
PPP1R11 PPP1R2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATM ANXA2 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
DCTN2 DYNLRB1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ACTR2 ARPC3 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTN4 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21078666
VHL EGLN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22286099 17986458 26215701
ESR1 RTCB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31527615 19805454 20348541
ESR1 MYH9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21182205
HYPK NAA50 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
DDOST RPN1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CCDC124 RPSA â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
EIF2S3 RPSA â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
EIF3I ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 10706629
HMGB1 SRSF3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31694235 29721183
MYO1E MYH9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 26344197
PARP1 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20085707 34079125
VHL PDCD5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24469044 17353931
PIN1 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11940573 16713569
RAD23B PSMD4 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 20059542 7307429
XRCC5 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20085707 12393188
NUBP1 NUBP2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CCDC124 RPL6 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CCDC124 RPS19 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CCDC124 RPS11 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CCDC124 RPS21 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CCDC124 RPL22 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CCDC124 RPS28 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CCDC124 RPS3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
EIF3G RPSA â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
EIF3I RPSA â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H2BJ HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H2BJ HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
ESR1 PTGES3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
FAM21A WASH2P â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
EIF2S3 RPS11 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
IKBKG RELA â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 15489227
RPL6 RPS3A â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ATM H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18344987 26095369 21704408 22451927 11893489 20081839 16858402 9488723 22184063 11571274 21676867 32518374 27918549
PARP1 NFKB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25609649 16799643 16204234 11590148
EIF3G RPS28 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3G RPS3A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3G RPS19 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3G RPS21 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3I RPS28 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3I RPS11 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3I RPS19 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3I RPS21 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3I RPS3A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
LTV1 RPS28 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BCL10 IKBKG â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EIF3G RPS11 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
LTV1 RPS19 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TUBB3 TUBB4B â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
RPL6 RPS11 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
TAB1 XIAP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
VPS4A VPS4B â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
PAK2 PAK3 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
PARP1 HMGB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28190768 29721183 34079125
CACYBP SKP1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
UBE2D2 XIAP â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EEF1B2 RPS3A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
H2AX PARP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28796254 28242625 16377563 27728808 18406329 28514442 20000738 20085707 16522924
EEF1B2 RPL22 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PA2G4 RPL22 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PA2G4 RPL6 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
EEF1B2 RPS28 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EEF1B2 RPS11 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MTA1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18451880 16807247 12167865 11146623 12639951 31527615
UFM1 ARHGDIA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ARHGDIA UBE2R2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RPA2 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
BCL10 TAB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17158449 15327770 10882101
NFKB1 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20303354 12360479 16618413
TAB1 CFL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EIF2S3 EIF1AX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 641056 592399 429297
PIN1 EIF3G â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IKBKG RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15489227
NFKB1 TNIP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 19695220 35140242 14743216 25609649 21988832
XRCC1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24778456 18971944 12897160 15555565 30260704 34079125 14500814 16713569 9584196 20302655 34111398 15044383 20303835
PHAX RAD23A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RELA PIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19458071 19668231 16950761
EIF1AX EIF2S3 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
EIF2S3 RPS28 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
PTGES3 STIP1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
EIF2S3 EIF3I â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
RPS11 RPS3A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
NUBP2 NUBP1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 33961781 22863883
LTV1 RPS21 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
TUBA4A TUBB3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
LTV1 RPS11 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
LTV1 RPS3A â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
LTV1 RPSA â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
EIF1AX RPS21 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
EEF1B2 RPS21 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EEF1B2 RPS19 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
EIF1AX EIF3I â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
EIF1AX EIF3G â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
NFKB1 TXN â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
EIF2S3 EIF3G â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
ACTR2 DBNL â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
BOLA2 GLRX3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 27519415 32296183
VPS4B VPS4A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 11563910 26186194 12594041 28514442
EIF1AX RPSA â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
RAD23A PSMD4 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 12970176 5216668
EIF1AX RPS3A â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
EIF1AX RPS11 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
EIF1AX RPS28 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
EIF1AX RPS19 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RNF25 UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RPS11 RPSA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPS28 RPSA â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPS3A RPSA â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL6 RPSA â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CNOT4 UBE2D2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL22 RPS28 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPS28 RPS3A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL22 RPSA â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPL6 RPS28 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPS11 RPS28 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
DCTN2 DCTN6 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL6 RPS21 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTR2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CBFB RUNX1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CIAO1 FAM96B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMD4 RAD23B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPS19 RPSA â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPS21 RPSA â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL22 RPS21 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS19 RPS21 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC3 ARPC5L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
DDOST RPN1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3G EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD4 RAD23A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPS11 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPS3A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPS19 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS19 RPS28 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS21 RPS3A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS21 RPS28 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL22 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPS19 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPL6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS11 RPS21 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS11 RPS19 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS11 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS19 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
XRCC5 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H2AX ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATM H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 197.0 1.0 Omnipath 27410735 28544233 16426903 28797244 9488723 23847653 30197789 21930799 18158901 21693595 18848500 22819196 15603757 16760673 17570479 24688021 24793032 27458206 16531125 22028490 30154456 19230794 23202908 25852739 19059218 26073471 22247744 28259974 29584802 25691887 19049966 20368801 26700820 29386061 28124509 20613862 27550454 20847938 27388041 27752097 23269287 24480460 22237206 20461094 20971043 26941327 18285803 21690091 15279774 23891287 25847270 24490130 25349305 26906421 20637859 26314960 15286739 27780918 20454618 30013081 28671946 25218945 23742011 26391293 23972723 23382699 26416514 27442013 20703100 24726884 26512707 27332952 29641431 25287622 26295265 14643438 29163809 25264544 19895790 26504743 26113859 27431324 28790385 18413980 21283714 21787120 20205745 19781914 25093845 27135971 23227178 22224778 20923785 20860841 24244154 23386996 30065307 16858402 11879731 28009280 23343929 20192759 22761798 26855420 24378750 20068231 20580718 14504478 24893124 29048667 25661368 26860083 26019182 20488183 28764946 22205726 23977391 18471973 19591958 28239143 20542002 17525332 20495376 18755145 23050241 17782711 11571274 19473884 28431265 25742493 18248856 17690115 20684759 26317467 21727091 24651472 25827888 27164092 28587922 20976184 30723510 20471486 23772364 29794999 11893489 19014481 20165693 26671524 16997395 20936109 26114388 23845989 15138496 22761813 23355489 27455285 28943310 21348461 19647519 23678292 23166506 28099474 29434792 25249630 25269479 27310012 15177039 22559321 26045162 20865059 22972376 21148072 26760771 21188122 22962268 22768044 26711340 20460517 27845910 28855246
MTA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15226262 11146623 12527756 24413532
MTA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11146623 18451880 12167865 16807247
CRK CRKL â—¼   PHYSICAL_INTERACTION 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRK CRKL â—¼   SHARES_COMPLEX 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRK CRKL â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
ABL2 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 12198159 9642287 21602891 20068231 11956190 19380743 15886098 16713569 8194526 8875975 25814554 17474147 17016520 9480911
ACTR2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ACTR2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
MYH9 ARPC3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
XRCC5 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
ATM TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM RPA2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM PARP1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 29875999 15964794 11877377 17303408 9725899 16163361 14872059 23847781 9139719 10713094 9295339 20860841 16731533 12607003 22977173 7171818 15459660
ATM IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 27486774 21490922 20932476 20188669 18583959 22435563 28626800 24957606 16497931 21872579 20932475 19917246 16965765 23063077
ATM PPP1R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18250156
ATM EIF4EBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 9806882 17525332 10713094 21315178 17570479 26777338 10608806 11146653 12588975 18212344 29152614
IKBKG BCL10 â—¼   ENZYMATIC_REACTION ✅ 44.0 1.0 ACSN 11280761 11356195 11460167 12133805 12356734 14660645 15145317 15199157 15485931 15536066 16809782 16818229 16970925 17052756 17237376 17254973 17301840 17363905 17462996 17485448 17693255 17948050 18264101 18264787 18716620 19302050 20138012 20300203 20685844 21133840 21199863 21217011 21232017 21807870 21873235 22435554 23086447 23422957 23430059 24560716 24699077 24958845 2649237 28462531
BCL10 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 14695475 19897484 18287044 27070702 17363905
CBFB RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 25678665 11179217 14729951 24522927 23333304 20195544 17431401 14752096 11276260 2845103 15331439 10856244 11742995 26598521 22498736
CSNK2A2 HSPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10772927 12558502
CSNK2A2 EIF4EBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 11146653 12588975 18212344 9806882
CSNK2A2 PPP1R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18669648 18767875 18088087 20068231 8288648 17287340 18491316 18212344 15302935
CSNK2A2 UBE2R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12037680 18669648
CSNK2A2 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18971944 28416484 20507565 19118383 21576760 18583988 15066279 20471329 18452278 25477519 21592330 15367657 21118972 20533398
UBE2D2 EGLN1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
ESR1 PSMD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18457947 9253789 12648521 11696545 23580568
NFKB1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RELA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
IKBKG RELA â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
NFKB1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
TNIP1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21988832 16684768 18212736 20010814
IKBKG NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
NFKB1 SKP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
NFKB1 XIAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17435549 21725609 23178297 23572150
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15041463 18223231 14739605 16157589 18978816 18761050 15756023 18566231 16453001
TXN NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18786561 25609649 7788295
TNIP1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21988832 25609649 14743216 19695220
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
SKP1 RELA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
RELA XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15041463 18223231 14739605 16157589 18978816 18761050 15756023 18566231 16453001
RPA2 XRCC1 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 XRCC1 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
UBE2M SKP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 16647857 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 21863050
XIAP TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9878061 12048196 17560374 27107012 11865055 23818254
VHL UBE2D2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
XRCC5 UBE2V2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368